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[View Full Guide](https://www.webmd.com/sleep-disorders/default.htm) # Medical Reasons You Could Have Insomnia   Written by [Paul Frysh](https://www.webmd.com/bio/paul-frysh) Medically Reviewed by [Zilpah Sheikh, MD](https://www.webmd.com/bio/zilpah-sheikh) on June 19, 2025  **1**/17 ## What It Isn't Maybe you regularly stay out late because you love a good party, and now (surprise!) you're tired. Or you're at the office until the wee hours to get ahead at work. Those aren't examples of insomnia. Insomnia is when you *can't* fall asleep, even though you want to, or you can't stay asleep long enough.  **2**/17 ## Stress Events like a job loss or the death of a loved one often cause some sleepless nights. Your doctor might call it acute insomnia as long as it goes away on its own within a few nights. Long-term worry, as well as anxiety disorder, panic attacks, and [PTSD](https://www.webmd.com/mental-health/what-are-symptoms-ptsd), can lead to chronic insomnia, which is more serious.  **3**/17 ## Irregular Sleep Times A confused body clock can keep you up when it's time for bed. Perhaps that's the result of an inconsistent bedtime, a long flight from another time zone, working overnight, or changing shifts for your job. Some people simply have a different circadian rhythm that puts them out of sync with typical activities, so it's hard for them to sleep at "normal" times.  **4**/17 ## Mental Illness A troubled mental state plays a role more than half of the time. People with [depression](https://www.webmd.com/depression/what-is-depression) are far more likely to have sleep problems, including insomnia. So are those with anxiety, bipolar, and obsessive-compulsive disorders. The way your sleep is affected can offer clues to the type of illness. It's not uncommon to be diagnosed with a mental disorder after you seek help for insomnia.  **5**/17 ## Breathing Problems Heavy snoring could be sleep apnea, which cuts off your breathing and could wake you hundreds of times in a single night. You may not remember it, but you might feel groggy the next day. Sometimes it's related to your weight, but not always. Nasal allergies and [asthma](https://www.webmd.com/asthma/what-is-asthma) also could interfere with your breathing. A doctor can test you for these conditions, and help you manage and treat them. ### Featured  **6**/17 ## Dementia Along with loss of memory, Alzheimer's and other forms of [dementia](https://www.webmd.com/alzheimers/types-dementia) can unsettle some people when you'd normally expect them to sleep, and they get restless. It's known as "sundown syndrome" or "sundowning." The person may be confused, anxious, restless, or aggressive around bedtime, and start to pace, rock, or even wander off. Sometimes this behavior fades, but sometimes it keeps them awake all night.  **7**/17 ## Pain Whether from [arthritis](https://www.webmd.com/arthritis/understanding-arthritis-treatment), chronic back issues, [fibromyalgia](https://www.webmd.com/fibromyalgia/what-is-fibromyalgia), [cancer](https://www.webmd.com/cancer/understanding-cancer-basics), or another condition, pain can prevent you from peacefully drifting off or interrupt your rest. And to complicate the issue, sleeplessness can make pain hurt more as well, creating a cycle. You may need to deal with the symptoms separate from the illness that’s behind them.  **8**/17 ## Itching Conditions like [psoriasis](https://www.webmd.com/skin-problems-and-treatments/psoriasis/understanding-psoriasis-basics) and [eczema](https://www.webmd.com/skin-problems-and-treatments/eczema/atopic-dermatitis-eczema) can make your skin burn and itch so badly that it's all you can think about. No amount of counting sheep will distract you. And if you do fall asleep, you might scratch so hard it wakes you up again! Fortunately, there are things you can do to soothe your skin. If you don't know what's causing the itch, it's best to see your doctor.  **9**/17 ## Parkinson's Disease People with this disease tend to sleep less and wake up more often than others of a similar age. It interferes with brain and nerve signaling, and you're more likely to have sleep apnea and to get up to pee. The condition also seems to disrupt the important REM sleep stage. Related anxiety and depression can lead to sleep problems, too. But medications that help you sleep may cause added confusion for some with Parkinson's.  **10**/17 ## Menopause Usually in middle age, a woman's body slowly stops making [progesterone](https://www.webmd.com/vitamins/ai/ingredientmono-760/progesterone) and estrogen. The shifting balance of hormones, as well as other changes that typically happen in life at this time, can make you more sensitive to things like stress that affect sleep. Severe hot flashes -- surges of adrenaline that raise your body temperature -- could be so uncomfortable that you wake up drenched in sweat, sometimes several times a night.  **11**/17 ## PMS Women with premenstrual syndrome (PMS) and the more serious premenstrual dysphoric disorder ([PMDD](https://www.webmd.com/women/pms/premenstrual-dysphoric-disorder)) often have trouble sleeping. This usually happens shortly before or during your period. Hormone changes can affect your body's temperature and its production of melatonin, a hormone important for sleep. Also, mood changes due to PMS or PMDD may make it harder to get a good night's sleep.  **12**/17 ## Digestive Problems Gastrointestinal (GI) disorders like inflammatory bowel syndrome (IBS) and gastroesophageal reflex disease (GERD) are also linked to sleep problems. Some 55% of people with GI problems say they have insomnia. That's compared to 20% of those without GI issues. We don't know whether this is because digestive symptoms keep you up, because sleep loss makes GI problems worse, or both.  **13**/17 ## Pregnancy Most women -- 78% -- have trouble sleeping at some point during their pregnancies. There are lots of reasons for that, including: - Hormonal changes - Need to pee more often - Heartburn or [nausea](https://www.webmd.com/digestive-disorders/digestive-diseases-nausea-vomiting) - Trouble getting comfortable - Back pain or leg cramps - Anxiety - Vivid dreams Getting enough sleep is especially important when you're pregnant. Tell your doctor if you're having sleep problems.  **14**/17 ## Medications Drugs for allergies, heart disease, hypertension, thyroid problems, and depression -- especially SSRIs like [fluoxetine](https://www.webmd.com/drugs/2/drug-6997/prozac-oral/details) (Prozac) -- might cause insomnia. Meds for [ADHD](https://www.webmd.com/add-adhd/attention-deficit-hyperactivity-disorder-adhd) and Parkinson's disease can also keep you up, along with the [pseudoephedrine](https://www.webmd.com/drugs/2/drug-4908-821/pseudoephedrine-oral/pseudoephedrine-sustained-release-oral/details) found in many over-the-counter decongestants. Check with your doctor about adjusting or changing your medication if you think it affects your sleep.  **15**/17 ## Primary Insomnia This means there doesn't seem to be anything about your environment, physical health, or mental well-being that would cause sleep problems. Doctors think some people's brains simply stay more alert -- too alert -- when they should be sleeping. It's not yet clear, but this could be the result of some physical difference, possibly genetic, in the brain. Scientists continue to study the possible causes.  **16**/17 ## What Insomnia Does to You Lack of sleep can make you moody, cranky, anxious, and depressed. It could also be harder to think straight or remember things. And you're more likely to have an accident in your car or elsewhere that could injure you or someone else. Insomnia is linked to conditions like obesity, high blood pressure, diabetes, and heart disease, too. ### Featured  **17**/17 ## What May Help To help get your sleep cycle on track, start with your bedroom. It should be dark, quiet, safe, comfortable, and cool. Avoid caffeine; even in normal doses, it can cause insomnia. Consider a hot bath, reading, or light stretching before bed. Avoid loud activities and difficult discussions, as well as heavy, fatty foods. Exercise earlier in the day, and get some sunlight in the morning. Sources Update History Share Print Save IMAGES PROVIDED BY: 1\) Thinkstock 2\) Thinkstock 3\) Thinkstock 4\) Thinkstock 5\) Photolibrary 6\) Carson 7\) Thinkstock 8\) Thinkstock 9\) Thinkstock 10\) Thinkstock 11\) Getty Images / monkeybusinessimages 12\) Getty Images / nycshooter 13\) Getty Images / becon 14\) Thinkstock 15\) Thinkstock 16\) Thinkstock 17\) Thinkstock SOURCES: Sleep Education: "Insomnia," "Insomnia -- Symptoms & Causes," "Jet Lag -- Overview." Healthy Sleep: "An Overview of Sleep Disorders," "Jet Lag and Shift Work," "You and Your Biological Clock," "Individual Variation and the Genetics of Sleep," "External Factors that Influence Sleep," "Sleep, Performance, and Public Safety," "Sleep and Disease Risk," "Twelve Simple Tips to Improve Your Sleep." National Jewish Health: "Insomnia Causes," "Medical Conditions That Cause Insomnia," "Medicines That Can Cause Insomnia." National Sleep Foundation: "What Causes Insomnia?" "Parkinson's Disease and Sleep," "Menopause and Insomnia," "Sleep Hygiene," "Caffeine and Sleep." Mayo Clinic: "Insomnia." National Alliance on Mental Illness: "Sleep Disorders: The Connection Between Sleep And Mental Health." AARP: "10 Ways to Manage Sundown Syndrome." Cleveland Clinic: "How to Beat Insomnia When You Have Chronic Pain." *International Journal of Molecular Sciences*: "Nocturnal Pruritus: The Battle for a Peaceful Night's Sleep." American Parkinson Disease Association: "Sleep Problems." UpToDate: "Treatment of menopausal symptoms with hormone therapy," "Patient education: Insomnia (Beyond the Basics)." *Encyclopedia of Sleep*: "Psychophysiological Insomnia." *Sleep*: "Chronic Psychophysiological Insomnia: Hyperarousal and/or Inhibition Deficits? An ERPs Investigation." Sleep Foundation: "PMS and Insomnia," "Pregnancy and Sleep." GI Society: "Sleep." 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