🕷️ Crawler Inspector

URL Lookup

Direct Parameter Lookup

Raw Queries and Responses

1. Shard Calculation

Query:
Response:
Calculated Shard: 177 (from laksa008)

2. Crawled Status Check

Query:
Response:

3. Robots.txt Check

Query:
Response:

4. Spam/Ban Check

Query:
Response:

5. Seen Status Check

ℹ️ Skipped - page is already crawled

📄
INDEXABLE
CRAWLED
5 days ago
🤖
ROBOTS ALLOWED

Page Info Filters

FilterStatusConditionDetails
HTTP statusPASSdownload_http_code = 200HTTP 200
Age cutoffPASSdownload_stamp > now() - 6 MONTH0.2 months ago
History dropPASSisNull(history_drop_reason)No drop reason
Spam/banPASSfh_dont_index != 1 AND ml_spam_score = 0ml_spam_score=0
CanonicalPASSmeta_canonical IS NULL OR = '' OR = src_unparsedNot set

Page Details

PropertyValue
URLhttps://www.vocabulary.com/dictionary/antidepressant
Last Crawled2026-04-11 10:40:12 (5 days ago)
First Indexed2013-08-10 09:22:11 (12 years ago)
HTTP Status Code200
Meta TitleAntidepressant - Definition, Meaning & Synonyms | Vocabulary.com
Meta DescriptionAn antidepressant is a drug used to treat depression. Unfortunately, many antidepressants have unwanted side effects.
Meta Canonicalnull
Boilerpipe Text
SKIP TO CONTENT /æntaɪdɪˈprɛsənt/ /æntaɪdɪˈprɛsənt/ IPA guide Other forms: antidepressants An antidepressant is a drug used to treat depression. Unfortunately, many antidepressants have unwanted side effects. Depression is a form of extreme sadness, when you're so sad that it impairs your ability to function. Words starting with anti are the opposite or go against other things. Antidepressants, then, are drugs that fight depression. If you’re depressed, a doctor can prescribe an antidepressant such as Prozac or Zoloft. Antidepressants can improve your mood, but they often have side effects such as weight gain or headaches. Definitions of antidepressant noun any of a class of drugs used to treat depression; often have undesirable side effects see more see less types: MAOI , monoamine oxidase inhibitor any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate maleate a salt or ester of maleic acid; used as a nontricyclic antidepressant drug for psychomotor activation desipramine a tricyclic antidepressant drug that activates the psychomotor system Prozac , Sarafem , fluoxetine , fluoxetine hydrocholoride a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain iproclozide an antidepressant drug that acts as a monoamine oxidase inhibitor Marplan , isocarboxazid a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression Pamelor , nortriptyline a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs Paxil , paroxetime a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Paxil) Nardil , phenelzine monoamine oxidase inhibitor (trade name Nardil) used to treat clinical depression protriptyline tricyclic antidepressant used to treat clinical depression Zoloft , sertraline a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Zoloft) tranylcypromine an antidepressant drug that is a monoamine oxidase inhibitor; administered as a sulfate Surmontil , trimipramine tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia type of: Style: MLA MLA APA Chicago "Antidepressant." Vocabulary.com Dictionary, Vocabulary.com, https://www.vocabulary.com/dictionary/antidepressant. Accessed 11 Apr. 2026. Copy citation loading examples... DISCLAIMER: These example sentences appear in various news sources and books to reflect the usage of the word ‘antidepressant' . Views expressed in the examples do not represent the opinion of Vocabulary.com or its editors. Send us feedback Sign up now (it’s free!) Whether you’re a teacher or a learner, Vocabulary.com can put you or your class on the path to systematic vocabulary improvement. Get started
Markdown
[SKIP TO CONTENT](https://www.vocabulary.com/dictionary/antidepressant#hdr-word-area) [![Vocabulary.com](https://cdn.vocabulary.com/images/header/logo-1wobq9i.png)![](https://cdn.vocabulary.com/images/logo-sar2cf.svg)](https://www.vocabulary.com/ "Vocabulary.com") - [Dictionary](https://www.vocabulary.com/dictionary/) - [Vocabulary Lists](https://www.vocabulary.com/lists/) - [VocabTrainer™](https://www.vocabulary.com/vocabtrainer/) Word Finder All Dictionary Vocabulary Lists [Random Word](https://www.vocabulary.com/randomword) Featured Dictionary Vocabulary Lists [More results](https://www.vocabulary.com/search-results) [Random Word](https://www.vocabulary.com/randomword) # antidepressant [Add to list]("Add to Vocabulary List") Share Copy link /æntaɪdɪˈprɛsənt/ /æntaɪdɪˈprɛsənt/ [IPA guide](https://www.vocabulary.com/resources/ipa-pronunciation/) Other forms: **antidepressants** An *antidepressant* is a drug used to treat depression. Unfortunately, many *antidepressants* have unwanted side effects. Depression is a form of extreme sadness, when you're so sad that it impairs your ability to function. Words starting with *anti* are the opposite or go against other things. Antidepressants, then, are drugs that fight depression. If you’re depressed, a doctor can prescribe an antidepressant such as Prozac or Zoloft. Antidepressants can improve your mood, but they often have side effects such as weight gain or headaches. Definitions of antidepressant 1. noun any of a class of drugs used to treat depression; often have undesirable side effects synonyms: [antidepressant drug](https://www.vocabulary.com/dictionary/antidepressant%20drug) [see moresee less](https://www.vocabulary.com/dictionary/antidepressant#0) types: [show 23 types...]() [hide 23 types...]() [MAOI](https://www.vocabulary.com/dictionary/MAOI), [monoamine oxidase inhibitor](https://www.vocabulary.com/dictionary/monoamine%20oxidase%20inhibitor) any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate [Serzone](https://www.vocabulary.com/dictionary/Serzone), [nefazodone](https://www.vocabulary.com/dictionary/nefazodone) an antidepressant drug (trade name Serzone) [nontricyclic](https://www.vocabulary.com/dictionary/nontricyclic), [nontricyclic antidepressant](https://www.vocabulary.com/dictionary/nontricyclic%20antidepressant), [nontricyclic antidepressant drug](https://www.vocabulary.com/dictionary/nontricyclic%20antidepressant%20drug), [nontricyclic drug](https://www.vocabulary.com/dictionary/nontricyclic%20drug) a class of antidepressant drugs that are not tricyclic drugs and do not act by inhibiting MAO [Edronax](https://www.vocabulary.com/dictionary/Edronax), [reboxetine](https://www.vocabulary.com/dictionary/reboxetine) an antidepressant drug that blocks the reuptake of norepinephrine [SSRI](https://www.vocabulary.com/dictionary/SSRI), [selective-serotonin reuptake inhibitor](https://www.vocabulary.com/dictionary/selective-serotonin%20reuptake%20inhibitor) an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain [tricyclic](https://www.vocabulary.com/dictionary/tricyclic), [tricyclic antidepressant](https://www.vocabulary.com/dictionary/tricyclic%20antidepressant), [tricyclic antidepressant drug](https://www.vocabulary.com/dictionary/tricyclic%20antidepressant%20drug) an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain [maleate](https://www.vocabulary.com/dictionary/maleate) a salt or ester of maleic acid; used as a nontricyclic antidepressant drug for psychomotor activation [Elavil](https://www.vocabulary.com/dictionary/Elavil), [amitriptyline](https://www.vocabulary.com/dictionary/amitriptyline), [amitriptyline hydrochloride](https://www.vocabulary.com/dictionary/amitriptyline%20hydrochloride) a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications [clomipramine](https://www.vocabulary.com/dictionary/clomipramine) a tricyclic antidepressant drug [desipramine](https://www.vocabulary.com/dictionary/desipramine) a tricyclic antidepressant drug that activates the psychomotor system [Adapin](https://www.vocabulary.com/dictionary/Adapin), [Sinequan](https://www.vocabulary.com/dictionary/Sinequan), [doxepin](https://www.vocabulary.com/dictionary/doxepin), [doxepin hydrochloride](https://www.vocabulary.com/dictionary/doxepin%20hydrochloride) a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances) [Prozac](https://www.vocabulary.com/dictionary/Prozac), [Sarafem](https://www.vocabulary.com/dictionary/Sarafem), [fluoxetine](https://www.vocabulary.com/dictionary/fluoxetine), [fluoxetine hydrocholoride](https://www.vocabulary.com/dictionary/fluoxetine%20hydrocholoride) a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain [Imavate](https://www.vocabulary.com/dictionary/Imavate), [Tofranil](https://www.vocabulary.com/dictionary/Tofranil), [imipramine](https://www.vocabulary.com/dictionary/imipramine), [impramine hydrochloride](https://www.vocabulary.com/dictionary/impramine%20hydrochloride) a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression [iproclozide](https://www.vocabulary.com/dictionary/iproclozide) an antidepressant drug that acts as a monoamine oxidase inhibitor [Marplan](https://www.vocabulary.com/dictionary/Marplan), [isocarboxazid](https://www.vocabulary.com/dictionary/isocarboxazid) a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression [Pamelor](https://www.vocabulary.com/dictionary/Pamelor), [nortriptyline](https://www.vocabulary.com/dictionary/nortriptyline) a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs [Paxil](https://www.vocabulary.com/dictionary/Paxil), [paroxetime](https://www.vocabulary.com/dictionary/paroxetime) a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Paxil) [Nardil](https://www.vocabulary.com/dictionary/Nardil), [phenelzine](https://www.vocabulary.com/dictionary/phenelzine) monoamine oxidase inhibitor (trade name Nardil) used to treat clinical depression [protriptyline](https://www.vocabulary.com/dictionary/protriptyline) tricyclic antidepressant used to treat clinical depression [Zoloft](https://www.vocabulary.com/dictionary/Zoloft), [sertraline](https://www.vocabulary.com/dictionary/sertraline) a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Zoloft) [tranylcypromine](https://www.vocabulary.com/dictionary/tranylcypromine) an antidepressant drug that is a monoamine oxidase inhibitor; administered as a sulfate [Desyrel](https://www.vocabulary.com/dictionary/Desyrel), [trazodone](https://www.vocabulary.com/dictionary/trazodone), [trazodone hydrochloride](https://www.vocabulary.com/dictionary/trazodone%20hydrochloride) oral antidepressant (trade name Desyrel) that is a nontricyclic drug used as a sedative [Surmontil](https://www.vocabulary.com/dictionary/Surmontil), [trimipramine](https://www.vocabulary.com/dictionary/trimipramine) tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia type of: [medicament](https://www.vocabulary.com/dictionary/medicament), [medication](https://www.vocabulary.com/dictionary/medication), [medicinal drug](https://www.vocabulary.com/dictionary/medicinal%20drug), [medicine](https://www.vocabulary.com/dictionary/medicine) (medicine) something that treats or prevents or alleviates the symptoms of disease Cite this entry Style: MLA - MLA - APA - Chicago "Antidepressant." *Vocabulary.com Dictionary,* Vocabulary.com, https://www.vocabulary.com/dictionary/antidepressant. Accessed 11 Apr. 2026. Copy citation Examples from books and articles All sources - All sources - Literature - Arts / culture - News - Business - Sports - Science / Med - Technology loading examples... [\< prev]("prev") \| [next \>]("next") DISCLAIMER: These example sentences appear in various news sources and books to reflect the usage of the word **‘antidepressant'**. Views expressed in the examples do not represent the opinion of [Vocabulary.com](https://www.vocabulary.com/) or its editors. [Send us feedback](https://www.ixl.com/feedback/vocabularydotcom) Word Family - [antidepressant](https://www.vocabulary.com/dictionary/antidepressant)[antidepressants](https://www.vocabulary.com/dictionary/antidepressants) - [depressant](https://www.vocabulary.com/dictionary/depressant)[depressants](https://www.vocabulary.com/dictionary/depressants)[antidepressant](https://www.vocabulary.com/dictionary/antidepressant) - [depress](https://www.vocabulary.com/dictionary/depress)[depressed](https://www.vocabulary.com/dictionary/depressed)[depressing](https://www.vocabulary.com/dictionary/depressing)[depresses](https://www.vocabulary.com/dictionary/depresses)[depression](https://www.vocabulary.com/dictionary/depression)[depressive](https://www.vocabulary.com/dictionary/depressive)[depressant](https://www.vocabulary.com/dictionary/depressant)[depressor](https://www.vocabulary.com/dictionary/depressor) - [the "depress" family](https://www.vocabulary.com/dictionary/depress) ### Vocabulary lists containing **antidepressant** [Prefixes: anti-](https://www.vocabulary.com/lists/190360) The prefix "anti-" means "against," "in opposition to," or "opposite of." [MORE VOCABULARY LISTS](https://www.vocabulary.com/lists/) 2 million people are mastering new words. [Master a word](https://www.vocabulary.com/vocabtrainer/) ## Sign up now (it’s free!) ### Whether you’re a teacher or a learner, Vocabulary.com can put you or your class on the path to systematic vocabulary improvement. [Get started](https://www.vocabulary.com/signup/) Learn with us - [Learner subscriptions](https://www.vocabulary.com/learner-subscription/) - [Vocabulary lists](https://www.vocabulary.com/lists/) - [Dictionary](https://www.vocabulary.com/dictionary/) - [Test Prep](https://www.vocabulary.com/test-prep/) - [Join a Vocabulary Jam](https://www.vocabulary.com/jam/) - [Commonly confused words](https://www.vocabulary.com/articles/commonly-confused-words/) - [Word of the day](https://www.vocabulary.com/word-of-the-day/) [Teach with us](https://www.vocabulary.com/for-educators/) - [For educators](https://www.vocabulary.com/for-educators/) - [For schools and districts](https://www.vocabulary.com/for-administrators/) - [How it works](https://www.vocabulary.com/how-it-works/) - [Success stories](https://www.vocabulary.com/membership/success-stories/) - [Research](https://www.vocabulary.com/membership/research/) - [Professional development](https://www.vocabulary.com/professional-development/) - [Contact sales](https://www.vocabulary.com/membership/quote/) [Resources](https://www.vocabulary.com/help/) - [Help articles/FAQ](https://www.vocabulary.com/help/) - [Teaching resources](https://www.vocabulary.com/teaching-resources/) - [Learner resources](https://www.vocabulary.com/learner-resource-center/) - [ESL/ELL resources](https://www.vocabulary.com/english-language-learning-resources/) - [Grade level resources](https://www.vocabulary.com/lists/lists-by-grade/) - [IPA Pronunciation](https://www.vocabulary.com/resources/ipa-pronunciation/) - [Contact support](https://www.vocabulary.com/help/contactus) [Leaderboards](https://www.vocabulary.com/leaderboards/thisweek/) - [Vocabulary Bowl](https://www.vocabulary.com/bowl/) - [Today's leaders](https://www.vocabulary.com/leaderboards/today/) - [Weekly leaders](https://www.vocabulary.com/leaderboards/thisweek/) - [Monthly leaders](https://www.vocabulary.com/leaderboards/thismonth/) [About](https://www.vocabulary.com/about/) - [Our Mission](https://www.vocabulary.com/about/) - [Blog](https://www.vocabulary.com/blog/) - [Tell us what you think](https://www.ixl.com/feedback/vocabularydotcom) - [Privacy Policy](https://www.vocabulary.com/privacy/) - [Terms of Use](https://www.vocabulary.com/terms/) [![IXL Learning](https://cdn.vocabulary.com/images/footer/logo-ixl-for-ftr-190h5m.svg) Comprehensive K-12 personalized learning](https://www.ixl.com/) [![Rosetta Stone](https://cdn.vocabulary.com/images/footer/logo-rosetta-stone-for-ftr-cnz0xb.svg) Immersive learning for 25 languages](https://www.rosettastone.com/) [![Wyzant](https://cdn.vocabulary.com/images/footer/logo-wyzant-for-ftr-92dn93.svg) Trusted tutors ready to help in 300+ subjects](https://www.wyzant.com/) [![Education.com](https://cdn.vocabulary.com/images/footer/logo-education-com-for-ftr-a3xg4c.svg) 35,000 worksheets, games, and lesson plans](https://www.education.com/) [![TPT](https://cdn.vocabulary.com/images/footer/logo-tpt-for-ftr-pa6bkm.svg) Marketplace for millions of educator-created resources](https://www.teacherspayteachers.com/) [![ABCya](https://cdn.vocabulary.com/images/footer/logo-abcya-for-ftr-1or2r2i.svg) Fun educational games for kids](https://www.abcya.com/) [![SpanishDictionary.com](https://cdn.vocabulary.com/images/footer/logo-spanish-dictionary-for-ftr-hev0u7.svg) Spanish-English dictionary, translator, and learning](https://www.spanishdict.com/) [![Inglés.com](https://cdn.vocabulary.com/images/footer/logo-ingles-for-ftr-w00ql8.svg) Diccionario inglés-español, traductor y sitio de aprendizaje](https://www.ingles.com/) [![Emmersion](https://cdn.vocabulary.com/images/footer/logo-emmersion-for-ftr-1m00b4j.svg) Fast and accurate language certification](https://emmersion.ai/) [![FrenchDictionary.com](https://cdn.vocabulary.com/images/footer/logo-french-dictionary-for-ftr-nrqi20.svg) French-English dictionary, translator, and learning](https://www.frenchdictionary.com/) ![vocabulary.com logo](https://cdn.vocabulary.com/images/footer/logo-vocab-green-check-for-ftr-4lic3k.svg) Copyright © 2026 Vocabulary.com, Inc. A division of IXL Learning • All Rights Reserved. ![IXL logo](https://cdn.vocabulary.com/images/footer/logo-ixl-learning-ab1nek.svg) [![Facebook logo](https://cdn.vocabulary.com/images/footer/facebook-fff-on-000-1djwcsu.svg)](https://www.facebook.com/vocabularycom/ "Facebook") [![X.com logo](https://cdn.vocabulary.com/images/footer/x-fff-on-000-r417h3.svg)](https://x.com/VocabularyCom/ "x.com") [![Instagram logo](https://cdn.vocabulary.com/images/footer/instagram-fff-on-000-1nomn10.svg)](https://www.instagram.com/vocabcom/ "Instagram") [![LinkedIn logo](https://cdn.vocabulary.com/images/footer/linkedin-fff-on-000-rszenv.svg)](https://www.linkedin.com/company/vocabulary-com/ "LinkedIn") Learn with us - [Learner subscriptions](https://www.vocabulary.com/learner-subscription/) - [Vocabulary lists](https://www.vocabulary.com/lists/) - [Dictionary](https://www.vocabulary.com/dictionary/) - [Test Prep](https://www.vocabulary.com/test-prep/) - [Join a Vocabulary Jam](https://www.vocabulary.com/jam/) - [Commonly confused words](https://www.vocabulary.com/articles/commonly-confused-words/) - [Word of the day](https://www.vocabulary.com/word-of-the-day/) [Teach with us](https://www.vocabulary.com/for-educators/) - [For educators](https://www.vocabulary.com/for-educators/) - [For schools and districts](https://www.vocabulary.com/for-administrators/) - [How it works](https://www.vocabulary.com/how-it-works/) - [Success stories](https://www.vocabulary.com/membership/success-stories/) - [Research](https://www.vocabulary.com/membership/research/) - [Professional development](https://www.vocabulary.com/professional-development/) - [Contact sales](https://www.vocabulary.com/membership/quote/) [Resources](https://www.vocabulary.com/help/) - [Help articles/FAQ](https://www.vocabulary.com/help/) - [Teaching resources](https://www.vocabulary.com/teaching-resources/) - [Learner resources](https://www.vocabulary.com/learner-resource-center/) - [ESL/ELL resources](https://www.vocabulary.com/english-language-learning-resources/) - [Grade level resources](https://www.vocabulary.com/lists/lists-by-grade/) - [IPA Pronunciation](https://www.vocabulary.com/resources/ipa-pronunciation/) - [Contact support](https://www.vocabulary.com/help/contactus) [Leaderboards](https://www.vocabulary.com/leaderboards/thisweek/) - [Vocabulary Bowl](https://www.vocabulary.com/bowl/) - [Today's leaders](https://www.vocabulary.com/leaderboards/today/) - [Weekly leaders](https://www.vocabulary.com/leaderboards/thisweek/) - [Monthly leaders](https://www.vocabulary.com/leaderboards/thismonth/) [About](https://www.vocabulary.com/about/) - [Our Mission](https://www.vocabulary.com/about/) - [Blog](https://www.vocabulary.com/blog/) - [Tell us what you think](https://www.ixl.com/feedback/vocabularydotcom) - [Privacy Policy](https://www.vocabulary.com/privacy/) - [Terms of Use](https://www.vocabulary.com/terms/) [My Account](https://www.vocabulary.com/account/) [Log in](https://www.vocabulary.com/login/) [Sign up](https://www.vocabulary.com/signup/) - [Log Out](https://www.vocabulary.com/auth/logout) - [My Learning](https://www.vocabulary.com/learner/) - [My Proficiency Report](https://www.vocabulary.com/learner-subscription/) - [My Profile](https://www.vocabulary.com/profiles/my) - [Schools & Teachers](https://www.vocabulary.com/account/schools) - [My Classes](https://www.vocabulary.com/account/classes) - [Assignments & Activities](https://www.vocabulary.com/account/activities/) - [My Lists](https://www.vocabulary.com/account/lists/) - [Find a List to Learn...](https://www.vocabulary.com/lists/) - [Create a New List...](https://www.vocabulary.com/lists/new) - [My Progress](https://www.vocabulary.com/progress/) - [Words I'm Learning](https://www.vocabulary.com/account/progress/words/learning) - [My Trouble Words](https://www.vocabulary.com/account/progress/words/trouble) - [Words I've Mastered](https://www.vocabulary.com/account/progress/words/mastered) - [My Achievements](https://www.vocabulary.com/account/progress/achievements) - [User Administration](https://www.vocabulary.com/account/users) - [User Authentication](https://www.vocabulary.com/account/authentication) - [My Account](https://www.vocabulary.com/account/) [![IXL Learning](https://cdn.vocabulary.com/images/footer/logo-ixl-for-ftr-190h5m.svg) Comprehensive K-12 personalized learning](https://www.ixl.com/) [![Rosetta Stone](https://cdn.vocabulary.com/images/footer/logo-rosetta-stone-for-ftr-cnz0xb.svg) Immersive learning for 25 languages](https://www.rosettastone.com/) [![Wyzant](https://cdn.vocabulary.com/images/footer/logo-wyzant-for-ftr-92dn93.svg) Trusted tutors ready to help in 300+ subjects](https://www.wyzant.com/) [![Education.com](https://cdn.vocabulary.com/images/footer/logo-education-com-for-ftr-a3xg4c.svg) 35,000 worksheets, games, and lesson plans](https://www.education.com/) [![TPT](https://cdn.vocabulary.com/images/footer/logo-tpt-for-ftr-pa6bkm.svg) Marketplace for millions of educator-created resources](https://www.teacherspayteachers.com/) [![ABCya](https://cdn.vocabulary.com/images/footer/logo-abcya-for-ftr-1or2r2i.svg) Fun educational games for kids](https://www.abcya.com/) [![SpanishDictionary.com](https://cdn.vocabulary.com/images/footer/logo-spanish-dictionary-for-ftr-hev0u7.svg) Spanish-English dictionary, translator, and learning](https://www.spanishdict.com/) [![Inglés.com](https://cdn.vocabulary.com/images/footer/logo-ingles-for-ftr-w00ql8.svg) Diccionario inglés-español, traductor y sitio de aprendizaje](https://www.ingles.com/) [![Emmersion](https://cdn.vocabulary.com/images/footer/logo-emmersion-for-ftr-1m00b4j.svg) Fast and accurate language certification](https://emmersion.ai/) [![FrenchDictionary.com](https://cdn.vocabulary.com/images/footer/logo-french-dictionary-for-ftr-nrqi20.svg) French-English dictionary, translator, and learning](https://www.frenchdictionary.com/) ![vocabulary.com logo](https://cdn.vocabulary.com/images/footer/logo-vocab-green-check-for-ftr-4lic3k.svg) Copyright © 2026 Vocabulary.com, Inc. A division of IXL Learning • All Rights Reserved. ![IXL logo](https://cdn.vocabulary.com/images/footer/logo-ixl-learning-ab1nek.svg) [![Facebook logo](https://cdn.vocabulary.com/images/footer/facebook-fff-on-000-1djwcsu.svg)](https://www.facebook.com/vocabularycom/ "Facebook") [![X.com logo](https://cdn.vocabulary.com/images/footer/x-fff-on-000-r417h3.svg)](https://x.com/VocabularyCom/ "x.com") [![Instagram logo](https://cdn.vocabulary.com/images/footer/instagram-fff-on-000-1nomn10.svg)](https://www.instagram.com/vocabcom/ "Instagram") [![LinkedIn logo](https://cdn.vocabulary.com/images/footer/linkedin-fff-on-000-rszenv.svg)](https://www.linkedin.com/company/vocabulary-com/ "LinkedIn") [![](https://cdn.vocabulary.com/images/clear-16y9b5d.gif)](https://www.vocabulary.com/auth/admin)
Readable Markdown
[SKIP TO CONTENT](https://www.vocabulary.com/dictionary/antidepressant#hdr-word-area) /æntaɪdɪˈprɛsənt/ /æntaɪdɪˈprɛsənt/ [IPA guide](https://www.vocabulary.com/resources/ipa-pronunciation/) Other forms: **antidepressants** An *antidepressant* is a drug used to treat depression. Unfortunately, many *antidepressants* have unwanted side effects. Depression is a form of extreme sadness, when you're so sad that it impairs your ability to function. Words starting with *anti* are the opposite or go against other things. Antidepressants, then, are drugs that fight depression. If you’re depressed, a doctor can prescribe an antidepressant such as Prozac or Zoloft. Antidepressants can improve your mood, but they often have side effects such as weight gain or headaches. Definitions of antidepressant 1. noun any of a class of drugs used to treat depression; often have undesirable side effects [see moresee less](https://www.vocabulary.com/dictionary/antidepressant#0) types: [MAOI](https://www.vocabulary.com/dictionary/MAOI), [monoamine oxidase inhibitor](https://www.vocabulary.com/dictionary/monoamine%20oxidase%20inhibitor) any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate [maleate](https://www.vocabulary.com/dictionary/maleate) a salt or ester of maleic acid; used as a nontricyclic antidepressant drug for psychomotor activation [desipramine](https://www.vocabulary.com/dictionary/desipramine) a tricyclic antidepressant drug that activates the psychomotor system [Prozac](https://www.vocabulary.com/dictionary/Prozac), [Sarafem](https://www.vocabulary.com/dictionary/Sarafem), [fluoxetine](https://www.vocabulary.com/dictionary/fluoxetine), [fluoxetine hydrocholoride](https://www.vocabulary.com/dictionary/fluoxetine%20hydrocholoride) a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain [iproclozide](https://www.vocabulary.com/dictionary/iproclozide) an antidepressant drug that acts as a monoamine oxidase inhibitor [Marplan](https://www.vocabulary.com/dictionary/Marplan), [isocarboxazid](https://www.vocabulary.com/dictionary/isocarboxazid) a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression [Pamelor](https://www.vocabulary.com/dictionary/Pamelor), [nortriptyline](https://www.vocabulary.com/dictionary/nortriptyline) a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs [Paxil](https://www.vocabulary.com/dictionary/Paxil), [paroxetime](https://www.vocabulary.com/dictionary/paroxetime) a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Paxil) [Nardil](https://www.vocabulary.com/dictionary/Nardil), [phenelzine](https://www.vocabulary.com/dictionary/phenelzine) monoamine oxidase inhibitor (trade name Nardil) used to treat clinical depression [protriptyline](https://www.vocabulary.com/dictionary/protriptyline) tricyclic antidepressant used to treat clinical depression [Zoloft](https://www.vocabulary.com/dictionary/Zoloft), [sertraline](https://www.vocabulary.com/dictionary/sertraline) a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Zoloft) [tranylcypromine](https://www.vocabulary.com/dictionary/tranylcypromine) an antidepressant drug that is a monoamine oxidase inhibitor; administered as a sulfate [Surmontil](https://www.vocabulary.com/dictionary/Surmontil), [trimipramine](https://www.vocabulary.com/dictionary/trimipramine) tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia type of: Style: MLA - MLA - APA - Chicago "Antidepressant." *Vocabulary.com Dictionary,* Vocabulary.com, https://www.vocabulary.com/dictionary/antidepressant. Accessed 11 Apr. 2026. Copy citation loading examples... DISCLAIMER: These example sentences appear in various news sources and books to reflect the usage of the word **‘antidepressant'**. Views expressed in the examples do not represent the opinion of [Vocabulary.com](https://www.vocabulary.com/) or its editors. [Send us feedback](https://www.ixl.com/feedback/vocabularydotcom) ## Sign up now (it’s free!) ### Whether you’re a teacher or a learner, Vocabulary.com can put you or your class on the path to systematic vocabulary improvement. [Get started](https://www.vocabulary.com/signup/)
Shard177 (laksa)
Root Hash5066149262321948577
Unparsed URLcom,vocabulary!www,/dictionary/antidepressant s443