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Meta TitleWhat Is Sleep Myoclonus and Should You Be Concerned?
Meta DescriptionSleep myoclonus involves sudden, involuntary muscle movements during sleep. Learn its symptoms, causes, and when it may require treatment.
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Key Takeaways Sleep myoclonus is a normal, brief twitch or jerk that happens when you are falling asleep or sleeping.  Medical treatment is only necessary if myoclonus disrupts sleep or daily life. Sleep myoclonus describes brief, involuntary muscle twitching or jerking that typically happens as you're drifting off to sleep. It's more common in childhood but can linger through adulthood. Most of the time, sleep myoclonus is perfectly normal and nothing to worry about, but it may require medical attention if it disrupts your sleep or quality of life. Verywell / Emily Roberts How to Recognize Sleep Myoclonus Sleep myoclonus symptoms, which are easy to notice, include twitching, jerking, shaking, spasms, or muscle contractions. These may happen once or multiple times, either as a single event or throughout the night, with or without a pattern. Common characteristics of these symptoms are that they are: Brief Involuntary Localized to one part of the body or widespread Shock-like Sudden Variable in intensity and frequency Sleep myoclonus generally happens during the early stages of sleep, often as you're falling asleep. External stimuli like noise, movement, or light can sometimes trigger it. Why Does Sleep Myoclonus Happen?  Some known causes of sleep myoclonus are more likely to affect certain age groups. For instance, Parkinson's disease, which typically appears after age 60, can be a cause. The exact cause of sleep myoclonus remains unclear, but researchers propose a few theories. A main theory involves sleep atonia, a natural process where your muscles are paralyzed as you enter deeper sleep stages. During sleep atonia, movement signals from the brain relax. Occasionally, this transition is not smooth, leading to electrical signals that cause muscle spasms. Adults Some types of myoclonus, such as sleep myoclonus and hiccups, occur in all age groups. Other forms result from conditions that mainly affect adults, or from medications more commonly used by them. In adults, myoclonus may be triggered by: Medications: Some drugs, like opiates, antidepressants, antipsychotics, antiseizure medications (ASMs), and antibiotics, may cause myoclonus as a side effect. Stroke: After a stroke that damages a nerve pathway in the brain, myoclonus can develop. Neurological disease: Conditions such as multiple sclerosis , Parkinson's disease, dementia with Lewy bodies, Alzheimer's disease, celiac disease , and epilepsy can cause myoclonus. Trauma: Injuries to the brain, spinal cord, or nervous system that affect nerve pathways can trigger myoclonus. Metabolic disorders: Conditions like liver or kidney disease may lead to myoclonus. Infection: Nervous system infections, including herpes simplex virus and Lyme disease , can cause myoclonus. Cancer: Myoclonus is linked to cancers like leukemia, lymphoma, neuroblastoma, and lung, ovarian, or breast cancers. Unknown causes : This type is often called essential myoclonus. When doctors identify the underlying issue, they can better determine if treatment is needed. What Is Restless Leg Syndrome? Restless leg syndrome is a disorder that causes a person to experience a strong, uncontrolled urge to move their legs. This feeling can go away soon afterward or immediately upon experiencing the urge, but there are minor differences in how it feels between people. It has been observed to occur with sleep myoclonus. Children In infants, benign (non-threatening) sleep myoclonus appears as repetitive twitches in the arms, legs, or torso during sleep. Although research on infant myoclonus is limited, it is generally considered harmless. Occasionally, a healthcare provider may perform an electroencephalography (EEG) test to distinguish it from epilepsy. Other causes of myoclonus in children can include: Fever or infection: Abrupt episodes of myoclonus may occur after a child has a fever or infection, typically resolving on their own. Tumor: Neoblastoma is the most common type of malignant tumor in children seven years and younger. Approximately 2% to 3% of children with neoblastoma develop opsoclonus–myoclonus syndrome (OMS), which causes loss of coordination, tremors (often in the hands), and an inability to walk or sit. Trauma: A brain or spinal cord injury can also trigger myoclonus in children if it damages the nervous system. Brief episodes of myoclonus may begin immediately after the injury and often resolve abruptly on their own. What Are the Different Types of Myoclonus? There are two types of myoclonus: positive and negative myoclonus. Positive myoclonus happens when muscles abruptly contract. Negative myoclonus happens when muscles that are contracting suddenly stop. There are numerous forms of myoclonus, but some of them aren't sleep myoclonus: Action myoclonus is triggered by a movement you make or an intention to move, typically affecting the arms, legs, and face. It can be caused by brain damage due to a lack of oxygen, or happen as a symptom of another underlying neurological condition. Cortical myoclonus , which is one of the most common forms of myoclonus, typically affects the upper limbs and face. Cortical myoclonus may be positive, negative, or both at the same time. Epileptic myoclonus is common among people who live with epilepsy. It can happen as one component of a seizure, or on its own in the absence of a seizure. It typically happens in children with epilepsy. Essential myoclonus is myoclonus which may be the primary symptom of an underlying illness, the only symptom of an underlying illness, or idiopathic (unrelated to illness). It tends to be chronic. Myoclonus-renal failure syndrome is an extremely rare form of myoclonic epilepsy. Its symptoms may begin as early as age nine and progressively worsen, eventually leading to end-stage kidney failure. Palatal myoclonus is slow, rhythmic muscle contractions that can happen while asleep or awake, typically affecting the eyes, face, tongue, larynx (voice box), and the intercostal muscles between the ribs. Peripheral myoclonus rhythmic or sporadic jerking movements caused by a nerve injury or a lesion (i.e., a lipoma or other benign tumor) in a peripheral nerve, root nerves, or plexus nerves. Propriospinal myoclonus originates in the spine and may involve the neck, waist, knees, and hips, but not the face. It typically occurs in a lying down position, sometimes during the transition between wakefulness and sleep. It is more common in middle-aged men, and may be related to spinal, trauma, tumor, or infection. Startle syndrome is abrupt, rapid body jerking that happens when you are surprised by a sudden stimulus, such as a loud noise. It is normal and persists throughout life. Symptomatic myoclonus is spawned by a variety of underlying medical conditions, including Parkinson's, infection, kidney failure, hyperthyroidism, and even vitamin E deficiency. How It's Diagnosed To find the cause of myoclonus, your healthcare provider will first consider: Your age Medications you’re taking Recent falls, car accidents, or other injuries Family history Your provider will ask you about the tremors or spasms you experience. They may ask which body part seems to be affected, how frequently the myoclonus occurs, and how long the episodes seem to last. They may also ask if you are experiencing any other new or unusual symptoms. Depending on this information, your provider may recommend one or more of the following tests: Electroencephalogram (EEG) : Small discs (electrodes) are placed on your scalp to track your brainwaves for patterns that can reveal where the myoclonus starts. Electromyography (EMG) : Tiny needles through your skin and into your muscles to check the health of your muscles and the nerves that control them. Magnetic resonance imaging (MRI) : An MRI machine takes detailed images of your organs and tissues using magnetic fields and radio waves. MRIs do not involve radiation. Blood test: Your provider may order a blood test to check for signs of increased immune system activity, which can point to infection and other illnesses. What Are the Treatment Options? Sleep myoclonus is not considered serious or in need of treatment unless it interferes with sleep and/or someone's quality of life. If it does, the condition may be treated with Xenazine (tetrabenazine), a drug often used to treat movement disorders such as Huntington’s disease . In most cases, however, treatment is not necessary if sleep is relatively normal. Sleep myoclonus is widely referred to as a "benign" condition, meaning that it has no short- or long-term effects on the health or well-being of the affected individual. When to See a Healthcare Provider The occasional muscle jerk as you're drifting off to sleep is nothing to be concerned about. However, if the myoclonus is disrupting your sleep or happening while you are awake, see your healthcare provider for an evaluation. You should also see a healthcare provider if: The myoclonus happens persistently or frequently or is increasing in frequency The myoclonus interferes with eating, speaking, walking, or other activities You are experiencing a new type of myoclonus You have any other new or unusual symptoms, including signs of infection or signs of epilepsy Call 911 or go to the nearest urgent care if you if you experience any signs of epilepsy, including: Changes in consciousness Weakness Visual auras, such as flashes of light or tunnel vision Auditory (hearing) auras, such as ringing, buzzing, or distorted sounds Somatosensory auras, like tingling or a feeling of moving despite being still A metallic taste in your mouth A sudden sense of impending doom 14 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. National Institute of Neurological Disorders and Stroke. Myoclonus . National Institute on Aging. Parkinson's disease: Causes, symptoms, and treatments . SQ Online. Hypnic jerks: The mysterious sensation of falling and spazzing awake . Chanddarana M, Saraf U, Divya KP, Krishnan S, Kishore A. Myoclonus- a review . Ann Indian Acad Neurol . 2021 May;24(3):327-338. doi:10.4103/aian.AIAN_1180_20 Janssen S, Bloem B, van de Warrenburg B. The clinical heterogeneity of of drug-induced myoclonus: an illustrated review . J Neurol . 2017;264(8):1559-1566. doi:10.1007/s00415-016-8357-z Baylor Medicine. Myoclonus . Nichols J, Lee B, Chung K. A case of paraneoplastic myoclonus attributed to non-small cell lung cancer . Tremor Other Hyperkinet Mov (NY) . 2020 Jun;10(1):7. doi:10.5334/tohm.42 Mount Sinai. Restless legs syndrome and related disorders . Sleep Foundation. Benign neonatal sleep myoclonus . Delucchi V, Pavlidis E, Piccolo B, Pisani F. Febrile and postinfectious myoclonus: Case reports and review of the literature . Neuropediatrics . 2015 Geb;46(1):26-32. doi:10.1055/s-0034-1395347 Xie S, Bai C, Li K, Dong K, Yao W. Comparison of mediastinal and non-mediastinal neuroblastoma and ganglioneuroblastoma associated with opsoclonus-myoclonus syndrome: a systematic review and meta analysis . Transl Cancer Res . 2022 Oct;11(10):3741-3753. doi:10.21037/tcr-22-1120 Facini C, Barsacchi M, Piccolo B, Turco E, Pisani F. Early onset of propriospinal-like myoclonus in a child following a vertebral fracture . Neurology . 2016 Aug;87(9):1-2. doi:10.1212/WNL.0000000000003053 Bhowmick S, Lang A. Movement disorders and renal diseases . Move Dis . 2020 Oct;7(7):763-779. doi:10.1002/mdc3.13005 Johns Hopkins Medicine. Magnetic resonance imaging (MRI) . By Brandon Peters, MD Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine. Was this page helpful? Thanks for your feedback! What is your feedback?
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Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Ⓒ 2026 People Inc. — All rights reserved # What Is Sleep Myoclonus and Should You Be Concerned? By [Brandon Peters, MD](https://www.verywellhealth.com/brandon-peters-md-3014640) Updated on March 15, 2026 Medically reviewed by [Jonathan B. Jassey, DO](https://www.verywellhealth.com/jonathan-b-jassey-do-4775576) Table of Contents View All Table of Contents - [Symptoms](https://www.verywellhealth.com/what-is-sleep-myoclonus-3014807#toc-how-to-recognize-sleep-myoclonus) - [Causes](https://www.verywellhealth.com/what-is-sleep-myoclonus-3014807#toc-why-does-sleep-myoclonus-happen) - [Types](https://www.verywellhealth.com/what-is-sleep-myoclonus-3014807#toc-what-are-the-different-types-of-myoclonus) - [Diagnosis](https://www.verywellhealth.com/what-is-sleep-myoclonus-3014807#toc-how-its-diagnosed) - [Treatment](https://www.verywellhealth.com/what-is-sleep-myoclonus-3014807#toc-what-are-the-treatment-options) - [When to See a Healthcare Provider](https://www.verywellhealth.com/what-is-sleep-myoclonus-3014807#toc-when-to-see-a-healthcare-provider) ### Key Takeaways - Sleep myoclonus is a normal, brief twitch or jerk that happens when you are falling asleep or sleeping. - Medical treatment is only necessary if myoclonus disrupts sleep or daily life. Sleep myoclonus describes brief, involuntary muscle twitching or jerking that typically happens as you're drifting off to sleep. It's more common in childhood but can linger through adulthood. Most of the time, sleep myoclonus is perfectly normal and nothing to worry about, but it may require medical attention if it disrupts your sleep or quality of life. ![Causes of Sleep Myoclonus]() ![Causes of Sleep Myoclonus](https://www.verywellhealth.com/thmb/_Vv-S6tFx4kjXs85U0Gl_8SrHZ8=/1500x0/filters:no_upscale\(\):max_bytes\(150000\):strip_icc\(\)/what-is-sleep-myoclonus-3014807_final-7ed9480f6cd84571bd9019a52c2b0951.png) Verywell / Emily Roberts ## How to Recognize Sleep Myoclonus Sleep myoclonus symptoms, which are easy to notice, include twitching, jerking, shaking, spasms, or muscle contractions. These may happen once or multiple times, either as a single event or throughout the night, with or without a pattern. Common characteristics of these symptoms are that they are: - Brief - Involuntary - Localized to one part of the body or widespread - Shock-like - Sudden - Variable in intensity and frequency Sleep myoclonus generally happens during the early stages of sleep, often as you're falling asleep. External stimuli like noise, movement, or light can sometimes trigger it. ## Why Does Sleep Myoclonus Happen? Some known causes of sleep myoclonus are more likely to affect certain age groups. For instance, [Parkinson's](https://www.verywellhealth.com/parkinsons-disease-facts-5324573) disease, which typically appears after age 60, can be a cause. The exact cause of sleep myoclonus remains unclear, but researchers propose a few theories. A main theory involves sleep atonia, a natural process where your muscles are paralyzed as you enter deeper sleep stages. During sleep atonia, movement signals from the brain relax. Occasionally, this transition is not smooth, leading to electrical signals that cause muscle spasms. ### Adults Some types of myoclonus, such as sleep myoclonus and hiccups, occur in all age groups. Other forms result from conditions that mainly affect adults, or from medications more commonly used by them. In adults, myoclonus may be triggered by: - **Medications:** Some drugs, like opiates, antidepressants, antipsychotics, antiseizure medications (ASMs), and antibiotics, may cause myoclonus as a side effect. - **Stroke:** After a stroke that damages a nerve pathway in the brain, myoclonus can develop. - **Neurological disease:** Conditions such as [multiple sclerosis](https://www.verywellhealth.com/multiple-sclerosis-overview-4581925), Parkinson's disease, dementia with Lewy bodies, Alzheimer's disease, [celiac disease](https://www.verywellhealth.com/celiac-disease-symptoms-4014337), and epilepsy can cause myoclonus. - **Trauma:** Injuries to the brain, spinal cord, or nervous system that affect nerve pathways can trigger myoclonus. - **Metabolic disorders:** Conditions like liver or kidney disease may lead to myoclonus. - **Infection:** Nervous system infections, including herpes simplex virus and [Lyme disease](https://www.verywellhealth.com/lyme-disease-7151644), can cause myoclonus. - **Cancer:** Myoclonus is linked to cancers like leukemia, lymphoma, neuroblastoma, and lung, ovarian, or breast cancers. - **Unknown causes**: This type is often called essential myoclonus. When doctors identify the underlying issue, they can better determine if treatment is needed. ### What Is Restless Leg Syndrome? Restless leg syndrome is a disorder that causes a person to experience a strong, uncontrolled urge to move their legs. This feeling can go away soon afterward or immediately upon experiencing the urge, but there are minor differences in how it feels between people. It has been observed to occur with sleep myoclonus. ### Children In infants, benign (non-threatening) sleep myoclonus appears as repetitive twitches in the arms, legs, or torso during sleep. Although research on infant myoclonus is limited, it is generally considered harmless. Occasionally, a healthcare provider may perform an electroencephalography (EEG) test to distinguish it from epilepsy. Other causes of myoclonus in children can include: - **Fever or infection:** Abrupt episodes of myoclonus may occur after a child has a fever or infection, typically resolving on their own. - **Tumor:** Neoblastoma is the most common type of malignant tumor in children seven years and younger. Approximately 2% to 3% of children with neoblastoma develop opsoclonus–myoclonus syndrome (OMS), which causes loss of coordination, tremors (often in the hands), and an inability to walk or sit. - **Trauma:** A brain or spinal cord injury can also trigger myoclonus in children if it damages the nervous system. Brief episodes of myoclonus may begin immediately after the injury and often resolve abruptly on their own. ## What Are the Different Types of Myoclonus? There are two types of myoclonus: positive and negative myoclonus. Positive myoclonus happens when muscles abruptly contract. Negative myoclonus happens when muscles that are contracting suddenly stop. There are numerous forms of myoclonus, but some of them aren't sleep myoclonus: - **Action myoclonus** is triggered by a movement you make or an intention to move, typically affecting the arms, legs, and face. It can be caused by brain damage due to a lack of oxygen, or happen as a symptom of another underlying neurological condition. - **Cortical myoclonus**, whichis one of the most common forms of myoclonus, typically affects the upper limbs and face. Cortical myoclonus may be positive, negative, or both at the same time. - **Epileptic myoclonus** is common among people who live with epilepsy. It can happen as one component of a seizure, or on its own in the absence of a seizure. It typically happens in children with epilepsy. - **Essential myoclonus** is myoclonus which may be the primary symptom of an underlying illness, the only symptom of an underlying illness, or idiopathic (unrelated to illness). It tends to be chronic. - **Myoclonus-renal failure syndrome** is an extremely rare form of myoclonic epilepsy. Its symptoms may begin as early as age nine and progressively worsen, eventually leading to end-stage kidney failure. - **Palatal myoclonus** is slow, rhythmic muscle contractions that can happen while asleep or awake, typically affecting the eyes, face, tongue, larynx (voice box), and the intercostal muscles between the ribs. - **Peripheral myoclonus** rhythmic or sporadic jerking movements caused by a nerve injury or a lesion (i.e., a lipoma or other benign tumor) in a peripheral nerve, root nerves, or plexus nerves. - **Propriospinal myoclonus** originates in the spine and may involve the neck, waist, knees, and hips, but not the face. It typically occurs in a lying down position, sometimes during the transition between wakefulness and sleep. It is more common in middle-aged men, and may be related to spinal, trauma, tumor, or infection. - **Startle syndrome** is abrupt, rapid body jerking that happens when you are surprised by a sudden stimulus, such as a loud noise. It is normal and persists throughout life. - **Symptomatic myoclonus** is spawned by a variety of underlying medical conditions, including Parkinson's, infection, kidney failure, hyperthyroidism, and even vitamin E deficiency. ## How It's Diagnosed To find the cause of myoclonus, your healthcare provider will first consider: - Your age - Medications you’re taking - Recent falls, car accidents, or other injuries - Family history Your provider will ask you about the tremors or spasms you experience. They may ask which body part seems to be affected, how frequently the myoclonus occurs, and how long the episodes seem to last. They may also ask if you are experiencing any other new or unusual symptoms. Depending on this information, your provider may recommend one or more of the following tests: - [**Electroencephalogram (EEG)**](https://www.verywellhealth.com/what-is-an-eeg-test-and-what-is-it-used-for-3014879)**:** Small discs (electrodes) are placed on your scalp to track your brainwaves for patterns that can reveal where the myoclonus starts. - [**Electromyography (EMG)**](https://www.verywellhealth.com/electromyography-7152418)**:** Tiny needles through your skin and into your muscles to check the health of your muscles and the nerves that control them. - [**Magnetic resonance imaging (MRI)**](https://www.verywellhealth.com/what-is-an-mri-and-what-does-it-do-3157069)**:** An MRI machine takes detailed images of your organs and tissues using magnetic fields and radio waves. MRIs do not involve radiation. - **Blood test:** Your provider may order a blood test to check for signs of increased immune system activity, which can point to infection and other illnesses. ## What Are the Treatment Options? Sleep myoclonus is not considered serious or in need of treatment unless it interferes with sleep and/or someone's quality of life. If it does, the condition may be treated with Xenazine (tetrabenazine), a drug often used to treat movement disorders such as [Huntington’s disease](https://www.verywellhealth.com/huntingtons-disease-11697734). In most cases, however, treatment is not necessary if sleep is relatively normal. Sleep myoclonus is widely referred to as a "benign" condition, meaning that it has no short- or long-term effects on the health or well-being of the affected individual. ## When to See a Healthcare Provider The occasional muscle jerk as you're drifting off to sleep is nothing to be concerned about. However, if the myoclonus is disrupting your sleep or happening while you are awake, see your healthcare provider for an evaluation. You should also see a healthcare provider if: - The myoclonus happens persistently or frequently or is increasing in frequency - The myoclonus interferes with eating, speaking, walking, or other activities - You are experiencing a new type of myoclonus - You have any other new or unusual symptoms, including [signs of infection](https://www.verywellhealth.com/infection-symptoms-5185799) or [signs of epilepsy](https://www.verywellhealth.com/risks-and-complications-of-seizures-4685790) Call 911 or go to the nearest urgent care if you if you experience any signs of epilepsy, including: - Changes in consciousness - Weakness - Visual auras, such as flashes of light or tunnel vision - Auditory (hearing) auras, such as ringing, buzzing, or distorted sounds - Somatosensory auras, like tingling or a feeling of moving despite being still - A metallic taste in your mouth - A sudden sense of impending doom Read more: - [Health A-Z](https://www.verywellhealth.com/health-a-z-4014770) - [Sleep Disorders](https://www.verywellhealth.com/sleep-disorders-4014648) - [Insomnia & More Disorders](https://www.verywellhealth.com/insomnia-and-more-sleep-disorders-4013520) 14 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our [editorial process](https://www.verywellhealth.com/verywell-editorial-process-4777042) to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. 1. National Institute of Neurological Disorders and Stroke. [Myoclonus](https://www.ninds.nih.gov/health-information/disorders/myoclonus). 2. National Institute on Aging. [Parkinson's disease: Causes, symptoms, and treatments](https://www.nia.nih.gov/health/parkinsons-disease). 3. SQ Online. [Hypnic jerks: The mysterious sensation of falling and spazzing awake](https://sqonline.ucsd.edu/2021/05/hypnic-jerks-the-mysterious-sensation-of-falling-and-spazzing-awake/). 4. Chanddarana M, Saraf U, Divya KP, Krishnan S, Kishore A. [Myoclonus- a review](https://doi.org/10.4103%2Faian.AIAN_1180_20). *Ann Indian Acad Neurol*. 2021 May;24(3):327-338. doi:10.4103/aian.AIAN\_1180\_20 5. Janssen S, Bloem B, van de Warrenburg B. [The clinical heterogeneity of of drug-induced myoclonus: an illustrated review](https://doi.org/10.1007%2Fs00415-016-8357-z). *J Neurol*. 2017;264(8):1559-1566. doi:10.1007/s00415-016-8357-z 6. Baylor Medicine. [Myoclonus](https://www.bcm.edu/healthcare/specialties/neurology/parkinsons-disease-and-movement-disorders/myoclonus). 7. Nichols J, Lee B, Chung K. [A case of paraneoplastic myoclonus attributed to non-small cell lung cancer](https://doi.org/10.5334%2Ftohm.42). *Tremor Other Hyperkinet Mov (NY)*. 2020 Jun;10(1):7. doi:10.5334/tohm.42 8. Mount Sinai. [Restless legs syndrome and related disorders](https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders). 9. Sleep Foundation. [Benign neonatal sleep myoclonus](https://www.sleepfoundation.org/baby-sleep/benign-neonatal-sleep-myoclonus). 10. Delucchi V, Pavlidis E, Piccolo B, Pisani F. [Febrile and postinfectious myoclonus: Case reports and review of the literature](https://doi.org/10.1055/s-0034-1395347). *Neuropediatrics*. 2015 Geb;46(1):26-32. doi:10.1055/s-0034-1395347 11. Xie S, Bai C, Li K, Dong K, Yao W. [Comparison of mediastinal and non-mediastinal neuroblastoma and ganglioneuroblastoma associated with opsoclonus-myoclonus syndrome: a systematic review and meta analysis](https://doi.org/10.21037%2Ftcr-22-1120). *Transl Cancer Res*. 2022 Oct;11(10):3741-3753. doi:10.21037/tcr-22-1120 12. Facini C, Barsacchi M, Piccolo B, Turco E, Pisani F. [Early onset of propriospinal-like myoclonus in a child following a vertebral fracture](https://doi.org/10.1212/WNL.0000000000003053). *Neurology*. 2016 Aug;87(9):1-2. doi:10.1212/WNL.0000000000003053 13. Bhowmick S, Lang A. [Movement disorders and renal diseases](https://doi.org/10.1002/mdc3.13005). *Move Dis*. 2020 Oct;7(7):763-779. doi:10.1002/mdc3.13005 14. Johns Hopkins Medicine. [Magnetic resonance imaging (MRI)](https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/magnetic-resonance-imaging-mri). ![Brandon Peters, M.D.]() ![Brandon Peters, M.D.](https://www.verywellhealth.com/thmb/BbtKTL7wVNFD-4Y2KIj4azA0HpE=/144x144/filters:no_upscale\(\):max_bytes\(150000\):strip_icc\(\)/BrandonPetersMD_1000-5143e542c3084368b1220c4b86ede01c.png) By [Brandon Peters, MD](https://www.verywellhealth.com/brandon-peters-md-3014640) Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine. [See Our Editorial Process](https://www.verywellhealth.com/verywell-editorial-process-4777042) [Meet Our Medical Expert Board](https://www.verywellhealth.com/meet-our-medical-expert-board-11762003) Share Feedback Was this page helpful? Thanks for your feedback\! What is your feedback? 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### Key Takeaways - Sleep myoclonus is a normal, brief twitch or jerk that happens when you are falling asleep or sleeping. - Medical treatment is only necessary if myoclonus disrupts sleep or daily life. Sleep myoclonus describes brief, involuntary muscle twitching or jerking that typically happens as you're drifting off to sleep. It's more common in childhood but can linger through adulthood. Most of the time, sleep myoclonus is perfectly normal and nothing to worry about, but it may require medical attention if it disrupts your sleep or quality of life. Verywell / Emily Roberts ## How to Recognize Sleep Myoclonus Sleep myoclonus symptoms, which are easy to notice, include twitching, jerking, shaking, spasms, or muscle contractions. These may happen once or multiple times, either as a single event or throughout the night, with or without a pattern. Common characteristics of these symptoms are that they are: - Brief - Involuntary - Localized to one part of the body or widespread - Shock-like - Sudden - Variable in intensity and frequency Sleep myoclonus generally happens during the early stages of sleep, often as you're falling asleep. External stimuli like noise, movement, or light can sometimes trigger it. ## Why Does Sleep Myoclonus Happen? Some known causes of sleep myoclonus are more likely to affect certain age groups. For instance, [Parkinson's](https://www.verywellhealth.com/parkinsons-disease-facts-5324573) disease, which typically appears after age 60, can be a cause. The exact cause of sleep myoclonus remains unclear, but researchers propose a few theories. A main theory involves sleep atonia, a natural process where your muscles are paralyzed as you enter deeper sleep stages. During sleep atonia, movement signals from the brain relax. Occasionally, this transition is not smooth, leading to electrical signals that cause muscle spasms. ### Adults Some types of myoclonus, such as sleep myoclonus and hiccups, occur in all age groups. Other forms result from conditions that mainly affect adults, or from medications more commonly used by them. In adults, myoclonus may be triggered by: - **Medications:** Some drugs, like opiates, antidepressants, antipsychotics, antiseizure medications (ASMs), and antibiotics, may cause myoclonus as a side effect. - **Stroke:** After a stroke that damages a nerve pathway in the brain, myoclonus can develop. - **Neurological disease:** Conditions such as [multiple sclerosis](https://www.verywellhealth.com/multiple-sclerosis-overview-4581925), Parkinson's disease, dementia with Lewy bodies, Alzheimer's disease, [celiac disease](https://www.verywellhealth.com/celiac-disease-symptoms-4014337), and epilepsy can cause myoclonus. - **Trauma:** Injuries to the brain, spinal cord, or nervous system that affect nerve pathways can trigger myoclonus. - **Metabolic disorders:** Conditions like liver or kidney disease may lead to myoclonus. - **Infection:** Nervous system infections, including herpes simplex virus and [Lyme disease](https://www.verywellhealth.com/lyme-disease-7151644), can cause myoclonus. - **Cancer:** Myoclonus is linked to cancers like leukemia, lymphoma, neuroblastoma, and lung, ovarian, or breast cancers. - **Unknown causes**: This type is often called essential myoclonus. When doctors identify the underlying issue, they can better determine if treatment is needed. ### What Is Restless Leg Syndrome? Restless leg syndrome is a disorder that causes a person to experience a strong, uncontrolled urge to move their legs. This feeling can go away soon afterward or immediately upon experiencing the urge, but there are minor differences in how it feels between people. It has been observed to occur with sleep myoclonus. ### Children In infants, benign (non-threatening) sleep myoclonus appears as repetitive twitches in the arms, legs, or torso during sleep. Although research on infant myoclonus is limited, it is generally considered harmless. Occasionally, a healthcare provider may perform an electroencephalography (EEG) test to distinguish it from epilepsy. Other causes of myoclonus in children can include: - **Fever or infection:** Abrupt episodes of myoclonus may occur after a child has a fever or infection, typically resolving on their own. - **Tumor:** Neoblastoma is the most common type of malignant tumor in children seven years and younger. Approximately 2% to 3% of children with neoblastoma develop opsoclonus–myoclonus syndrome (OMS), which causes loss of coordination, tremors (often in the hands), and an inability to walk or sit. - **Trauma:** A brain or spinal cord injury can also trigger myoclonus in children if it damages the nervous system. Brief episodes of myoclonus may begin immediately after the injury and often resolve abruptly on their own. ## What Are the Different Types of Myoclonus? There are two types of myoclonus: positive and negative myoclonus. Positive myoclonus happens when muscles abruptly contract. Negative myoclonus happens when muscles that are contracting suddenly stop. There are numerous forms of myoclonus, but some of them aren't sleep myoclonus: - **Action myoclonus** is triggered by a movement you make or an intention to move, typically affecting the arms, legs, and face. It can be caused by brain damage due to a lack of oxygen, or happen as a symptom of another underlying neurological condition. - **Cortical myoclonus**, whichis one of the most common forms of myoclonus, typically affects the upper limbs and face. Cortical myoclonus may be positive, negative, or both at the same time. - **Epileptic myoclonus** is common among people who live with epilepsy. It can happen as one component of a seizure, or on its own in the absence of a seizure. It typically happens in children with epilepsy. - **Essential myoclonus** is myoclonus which may be the primary symptom of an underlying illness, the only symptom of an underlying illness, or idiopathic (unrelated to illness). It tends to be chronic. - **Myoclonus-renal failure syndrome** is an extremely rare form of myoclonic epilepsy. Its symptoms may begin as early as age nine and progressively worsen, eventually leading to end-stage kidney failure. - **Palatal myoclonus** is slow, rhythmic muscle contractions that can happen while asleep or awake, typically affecting the eyes, face, tongue, larynx (voice box), and the intercostal muscles between the ribs. - **Peripheral myoclonus** rhythmic or sporadic jerking movements caused by a nerve injury or a lesion (i.e., a lipoma or other benign tumor) in a peripheral nerve, root nerves, or plexus nerves. - **Propriospinal myoclonus** originates in the spine and may involve the neck, waist, knees, and hips, but not the face. It typically occurs in a lying down position, sometimes during the transition between wakefulness and sleep. It is more common in middle-aged men, and may be related to spinal, trauma, tumor, or infection. - **Startle syndrome** is abrupt, rapid body jerking that happens when you are surprised by a sudden stimulus, such as a loud noise. It is normal and persists throughout life. - **Symptomatic myoclonus** is spawned by a variety of underlying medical conditions, including Parkinson's, infection, kidney failure, hyperthyroidism, and even vitamin E deficiency. ## How It's Diagnosed To find the cause of myoclonus, your healthcare provider will first consider: - Your age - Medications you’re taking - Recent falls, car accidents, or other injuries - Family history Your provider will ask you about the tremors or spasms you experience. They may ask which body part seems to be affected, how frequently the myoclonus occurs, and how long the episodes seem to last. They may also ask if you are experiencing any other new or unusual symptoms. Depending on this information, your provider may recommend one or more of the following tests: - [**Electroencephalogram (EEG)**](https://www.verywellhealth.com/what-is-an-eeg-test-and-what-is-it-used-for-3014879)**:** Small discs (electrodes) are placed on your scalp to track your brainwaves for patterns that can reveal where the myoclonus starts. - [**Electromyography (EMG)**](https://www.verywellhealth.com/electromyography-7152418)**:** Tiny needles through your skin and into your muscles to check the health of your muscles and the nerves that control them. - [**Magnetic resonance imaging (MRI)**](https://www.verywellhealth.com/what-is-an-mri-and-what-does-it-do-3157069)**:** An MRI machine takes detailed images of your organs and tissues using magnetic fields and radio waves. MRIs do not involve radiation. - **Blood test:** Your provider may order a blood test to check for signs of increased immune system activity, which can point to infection and other illnesses. ## What Are the Treatment Options? Sleep myoclonus is not considered serious or in need of treatment unless it interferes with sleep and/or someone's quality of life. If it does, the condition may be treated with Xenazine (tetrabenazine), a drug often used to treat movement disorders such as [Huntington’s disease](https://www.verywellhealth.com/huntingtons-disease-11697734). In most cases, however, treatment is not necessary if sleep is relatively normal. Sleep myoclonus is widely referred to as a "benign" condition, meaning that it has no short- or long-term effects on the health or well-being of the affected individual. ## When to See a Healthcare Provider The occasional muscle jerk as you're drifting off to sleep is nothing to be concerned about. However, if the myoclonus is disrupting your sleep or happening while you are awake, see your healthcare provider for an evaluation. You should also see a healthcare provider if: - The myoclonus happens persistently or frequently or is increasing in frequency - The myoclonus interferes with eating, speaking, walking, or other activities - You are experiencing a new type of myoclonus - You have any other new or unusual symptoms, including [signs of infection](https://www.verywellhealth.com/infection-symptoms-5185799) or [signs of epilepsy](https://www.verywellhealth.com/risks-and-complications-of-seizures-4685790) Call 911 or go to the nearest urgent care if you if you experience any signs of epilepsy, including: - Changes in consciousness - Weakness - Visual auras, such as flashes of light or tunnel vision - Auditory (hearing) auras, such as ringing, buzzing, or distorted sounds - Somatosensory auras, like tingling or a feeling of moving despite being still - A metallic taste in your mouth - A sudden sense of impending doom 14 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our [editorial process](https://www.verywellhealth.com/verywell-editorial-process-4777042) to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. 1. National Institute of Neurological Disorders and Stroke. [Myoclonus](https://www.ninds.nih.gov/health-information/disorders/myoclonus). 2. National Institute on Aging. [Parkinson's disease: Causes, symptoms, and treatments](https://www.nia.nih.gov/health/parkinsons-disease). 3. SQ Online. [Hypnic jerks: The mysterious sensation of falling and spazzing awake](https://sqonline.ucsd.edu/2021/05/hypnic-jerks-the-mysterious-sensation-of-falling-and-spazzing-awake/). 4. Chanddarana M, Saraf U, Divya KP, Krishnan S, Kishore A. [Myoclonus- a review](https://doi.org/10.4103%2Faian.AIAN_1180_20). *Ann Indian Acad Neurol*. 2021 May;24(3):327-338. doi:10.4103/aian.AIAN\_1180\_20 5. Janssen S, Bloem B, van de Warrenburg B. [The clinical heterogeneity of of drug-induced myoclonus: an illustrated review](https://doi.org/10.1007%2Fs00415-016-8357-z). *J Neurol*. 2017;264(8):1559-1566. doi:10.1007/s00415-016-8357-z 6. Baylor Medicine. [Myoclonus](https://www.bcm.edu/healthcare/specialties/neurology/parkinsons-disease-and-movement-disorders/myoclonus). 7. Nichols J, Lee B, Chung K. [A case of paraneoplastic myoclonus attributed to non-small cell lung cancer](https://doi.org/10.5334%2Ftohm.42). *Tremor Other Hyperkinet Mov (NY)*. 2020 Jun;10(1):7. doi:10.5334/tohm.42 8. Mount Sinai. [Restless legs syndrome and related disorders](https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders). 9. Sleep Foundation. [Benign neonatal sleep myoclonus](https://www.sleepfoundation.org/baby-sleep/benign-neonatal-sleep-myoclonus). 10. Delucchi V, Pavlidis E, Piccolo B, Pisani F. [Febrile and postinfectious myoclonus: Case reports and review of the literature](https://doi.org/10.1055/s-0034-1395347). *Neuropediatrics*. 2015 Geb;46(1):26-32. doi:10.1055/s-0034-1395347 11. Xie S, Bai C, Li K, Dong K, Yao W. [Comparison of mediastinal and non-mediastinal neuroblastoma and ganglioneuroblastoma associated with opsoclonus-myoclonus syndrome: a systematic review and meta analysis](https://doi.org/10.21037%2Ftcr-22-1120). *Transl Cancer Res*. 2022 Oct;11(10):3741-3753. doi:10.21037/tcr-22-1120 12. Facini C, Barsacchi M, Piccolo B, Turco E, Pisani F. [Early onset of propriospinal-like myoclonus in a child following a vertebral fracture](https://doi.org/10.1212/WNL.0000000000003053). *Neurology*. 2016 Aug;87(9):1-2. doi:10.1212/WNL.0000000000003053 13. Bhowmick S, Lang A. [Movement disorders and renal diseases](https://doi.org/10.1002/mdc3.13005). *Move Dis*. 2020 Oct;7(7):763-779. doi:10.1002/mdc3.13005 14. Johns Hopkins Medicine. [Magnetic resonance imaging (MRI)](https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/magnetic-resonance-imaging-mri). ![Brandon Peters, M.D.](https://www.verywellhealth.com/thmb/BbtKTL7wVNFD-4Y2KIj4azA0HpE=/144x144/filters:no_upscale\(\):max_bytes\(150000\):strip_icc\(\)/BrandonPetersMD_1000-5143e542c3084368b1220c4b86ede01c.png) By [Brandon Peters, MD](https://www.verywellhealth.com/brandon-peters-md-3014640) Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine. Was this page helpful? Thanks for your feedback\! What is your feedback?
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