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1. Shard Calculation

Query:

Response:

Calculated Shard: 50 (from laksa180)

2. Crawled Status Check

Query:

curl -X POST \
  'http://laksa050.int.ahrefs:8124/' \
  -H 'Content-Type: text/plain' \
  -H 'X-ClickHouse-Database: crawler3' \
  -H 'Authorization: Basic YXBpOg==' \
  -d 'SELECT getAhrefsURLFromUnparsed(src_unparsed) AS found_url, ifNull(toUnixTimestamp(download_stamp), 0) AS crawl_time, ifNull(toUnixTimestamp(props_url_first_seen), 0) AS first_indexed_time, download_http_code AS http_code, src_unparsed AS src_unparsed, src_root_hash AS src_root_hash, history_drop_reason AS history_drop_reason, meta_title AS meta_title, meta_descriptions AS meta_descriptions, attrs_boilerpipe_text AS attrs_boilerpipe_text, attrs_markdown AS attrs_markdown, attrs_readable_markdown AS attrs_readable_markdown, meta_canonical AS meta_canonical FROM crawler3.page_info_local FINAL PREWHERE (src_root_hash, src_unparsed) IN ((getAhrefsRootHashFromUnparsed(getAhrefsUnparsedNoserviceFromURL(\'https://www.verywellhealth.com/reasons-why-you-feel-sleepy-3014818\')), getAhrefsUnparsedNoserviceFromURL(\'https://www.verywellhealth.com/reasons-why-you-feel-sleepy-3014818\'))) FORMAT JSONEachRow'

Response:

{"found_url":"https:\/\/www.verywellhealth.com\/reasons-why-you-feel-sleepy-3014818","crawl_time":1776090813,"first_indexed_time":1525955647,"http_code":200,"src_unparsed":"com,verywellhealth!www,\/reasons-why-you-feel-sleepy-3014818 s443","src_root_hash":"5681562863987870850","history_drop_reason":null,"meta_title":"Why Am I Always Tired?","meta_descriptions":["Learn about lifestyle, health conditions, and sleep disorders that cause fatigue, and find out how to tackle constant tiredness."],"attrs_boilerpipe_text":"Key Takeaways\nFatigue can be caused by medical conditions like sleep apnea, diabetes, or thyroid disease. \nPoor sleep habits, such as not getting enough sleep or having an uncomfortable sleeping environment, can make you tired.\nLifestyle choices, such as unhealthy diet, dehydration, and lack of exercise, can decrease your energy levels.\nThe causes of constant tiredness and fatigue can stem from various factors that affect your energy levels throughout the day. These causes typically fall into four categories: lifestyle factors, medical conditions, sleep disorders, and mental health issues.\nVerywell \/ Cindy Chung \n1:39\nClick Play to Learn What You Can Do to Feel Less Tired\nEveryday Habits That Can Make You Tired \nYour daily habits can significantly affect how alert and energetic you feel throughout the day. Consider discussing the following factors with your healthcare provider:\nDiet:\nYour body gets energy from food. An unbalanced diet or skipping meals can make you feel tired. Diet-related causes of fatigue include deficiencies in zinc, vitamin B12, or vitamin D, blood sugar changes, excessive alcohol, and too much caffeine.\nDehydration\n:\nDehydration occurs when you lose more fluids than you take in. Since water makes up 50% to 60% of your body weight, sweating, urination, heat, or illness can quickly deplete your hydration levels.\nWhile drinking eight 8-ounce glasses of water daily is a common guideline, very pale yellow or clear urine generally indicates proper hydration.\nPoor sleep habits:\nDaytime fatigue may result from not getting enough quality sleep. Poor habits like sleeping in a noisy or uncomfortable environment, skipping a bedtime routine, exercising too close to bedtime, or napping late in the day can disrupt your rest. Additionally, not meeting the sleep needs for your age (eight to nine hours a night for adults ages 18 to 60) can leave you feeling tired.\nInactive lifestyle\n:\nSitting for long periods can lead to restless and poor-quality sleep. Engaging in regular physical activity can improve your sleep and mental well-being. One study found that participants who exercised for 150 minutes a week experienced less insomnia, depression, and anxiety compared to those who were less active..\nOverexertion:\nOverexerting yourself through excessive exercise or other activities can leave your body too depleted to recover. This can lead to fatigue, poor sleep, and low motivation. Symptoms of overexertion may include mood swings, sore limbs, frequent illness, and a decline in performance at work or home.\nStress\n:\nStress can disrupt your sleep, and poor sleep can increase stress and fatigue. A survey found 43% of adults lost sleep due to stress, and 37% reported feeling tired because of it.\nGetting quality sleep helps maintain a positive mood during stressful times and increases joy from good experiences.\nCould a Health Condition Be Draining Your Energy?\nFeeling fatigued, weak, or sleepy can be symptoms of various medical conditions that impact your energy. Daytime sleepiness may be linked to these underlying causes:\nAnemia\n:\nAnemia is a condition in which your body has fewer red blood cells or they don't function properly, reducing the blood's ability to deliver oxygen to your organs. This can cause symptoms like fatigue, headaches, difficulty concentrating, irritability, and numbness in the hands and feet.\nThe most common type is iron-deficiency anemia, but other causes include inherited disorders, chronic illnesses, and pregnancy.\nAutoimmune disease:\nAutoimmune diseases occur when your immune system mistakenly attacks your own body, causing tissue damage and chronic inflammation. Conditions like rheumatoid arthritis, lupus, multiple sclerosis, and\ninflammatory bowel disease\ncan lead to fatigue and disrupt your metabolism, nervous system, and sleep patterns. They may also cause imbalances in cytokines, proteins that regulate inflammation, mood, and sleep.\nCancer:\nMore than 80% of people with cancer experience\ncancer-related fatigue\n, which often doesn't improve with rest and can be an early sign of the disease. Fatigue can result from low blood counts, disturbed electrolytes, altered hormone or cytokine levels, and changes in cell function caused by cancer. Treatments like chemotherapy, immunotherapy, and radiation can also contribute to fatigue.\nChronic fatigue syndrome\n:\nChronic fatigue syndrome (ME\/CFS) causes extreme fatigue that worsens with minimal exertion, doesn't improve with rest, and often includes flu-like symptoms and cognitive issues like \"brain fog.\" The exact cause is unknown, but it may be linked to infections, chronic stress, autoimmune responses, or cytokine-related inflammation.\nChronic obstructive pulmonary disease\n(COPD):\nThis chronic disease causes wheezing, shortness of breath, and extra mucus, making it hard to breathe. Fatigue is common in COPD, but it may not always be directly linked to breathing difficulties. The disease progresses over time, and it is especially common in current or former smokers.\nDepression:\nThis mood disorder causes sadness, loss of interest, and physical symptoms like fatigue. Daytime sleepiness may result from insomnia or other sleep problems often linked to depression, and fatigue may serve as an early warning sign.\nBiochemical similarities between depression and ME\/CFS might explain fatigue as a shared symptom.\nDiabetes\n:\nDiabetes fatigue syndrome refers to persistent fatigue experienced by people with diabetes. Possible causes include low blood sugar, hormonal imbalances, treatment side effects, overlapping conditions, and lifestyle factors like diet.\nFibromyalgia\n:\nFibromyalgia\nis a chronic pain condition. It's caused by dysfunction in the central nervous system, which heightens sensitivity and turns harmless sensations into pain (allodynia).\nFatigue is also a key symptom of fibromyalgia. This fatigue may be due to biochemical changes, inflammation, sleep disorders, and sleep disruptions.\nHeart disease:\nIf you have fatigue that's new and constant, it may be an early warning sign of heart failure or, less often,\ncoronary artery disease\n. These conditions limit the amount of oxygen-rich blood that gets to your muscles or to the heart itself. Your heart and brain need oxygen. When you have heart disease, your body limits the blood sent to less important parts like the limbs, leading to reduced energy and fatigue.\nInfections:\nFatigue is common during and after infectious illnesses like COVID-19, influenza, mononucleosis, and\nLyme disease\n. While tiredness often resolves as the illness clears, some people experience lingering fatigue, known as post-viral fatigue or,\nin the case of COVID-19, long COVID\n.\nResearchers are exploring links between these persistent symptoms and conditions like ME\/CFS, especially for viruses like Epstein-Barr, which can reactivate and contribute to fatigue and autoimmune diseases.\nFood allergies and intolerances\n:\nFood allergies and intolerances can cause fatigue by triggering immune responses or gastrointestinal distress that depletes energy levels. Reactions to allergens, such as dairy, gluten, or nuts, may lead to inflammation, poor nutrient absorption, or disrupted sleep. Chronic exposure to problematic foods can worsen fatigue over time, especially if the underlying issue goes unaddressed.\nKidney disease\n:\nKidney disease can cause fatigue due to the buildup of toxins in the blood when the kidneys are not functioning properly. This can lead to anemia, as the kidneys produce less erythropoietin, a hormone essential for red blood cell production.\nElectrolyte imbalances and reduced nutrient absorption may also contribute to low energy levels.\nMenopause\n:\nThe transition to menopause, including perimenopause and the early post-menopausal stage, often brings fatigue along with symptoms like hot flashes, night sweats, and mood swings. Fatigue may stem from sleep disruptions, hormonal changes, aging, or stress.\nPregnancy\n:\nPregnancy places extra demands on the body, often causing fatigue, especially during the first and third trimesters. Factors contributing to this tiredness include the energy required to support the baby, hormonal changes, low blood sugar or pressure, and disrupted sleep. Stress and digestive changes can also play a role in pregnancy-related exhaustion.\nThyroid disease\n:\nThyroid hormone imbalances, whether high (hyperthyroidism) or low (hypothyroidism), can cause fatigue due to their effects on metabolism. Hyperthyroidism speeds up bodily processes, leading to symptoms like anxiety, sleep disruption, and eventual exhaustion as energy reserves deplete, while hypothyroidism slows everything down, causing fatigue alongside weight gain, depression, and memory problems.\nRecognizing a Heart Attack\nA heart attack requires immediate medical attention. Call 9-1-1 if you or someone else suddenly experiences:\nChest pain or pressure, which can also be in the upper abdomen\nPain that spreads to the jaw, neck, back, arms, or stomach\nShortness of breath\nDizziness or fainting\nNausea or vomiting\nExtreme fatigue\nHow Sleep Disorders Affect Your Energy Levels\nVarious circadian rhythm disorders can leave you\nfeeling too sleepy during the day\n. The circadian rhythm is your body's natural clock. It helps to coordinate your activities based on when it's light and dark in your environment. If your internal timing is misaligned, you may find yourself with excessive daytime sleepiness.\nSix common circadian rhythm disorders include:\nAdvanced sleep phase syndrome:\nThe distinguishing feature is falling asleep and waking up earlier than you want, usually by about three hours.\nDelayed sleep phase syndrome:\nThis causes difficulty falling asleep and makes it extremely hard to wake up.\nIrregular sleep-wake rhythm:\nThis occurs when the circadian rhythm becomes completely disconnected from the natural day-night cycle. Sleep is fragmented, with short spells scattered throughout the day.\nJet lag:\nA temporary rhythm disorder associated with travel across several time zones. To adjust, it may take one day for every time zone you cross.\nNon-entrained (non-24) disorder:\nThis usually occurs in visually impaired people. The sleep cycle is typically a little longer than average and thus becomes more out of sync every day.\nShift-work sleep disorder:\nPoor sleep is caused by working at night and sleeping during the day. This can lead to increased accidents and possibly a higher risk of some forms of cancer.\nOther sleep disorders that can result in constant tiredness or fatigue include:\nInsomnia\n:\nInsomnia, which makes it hard to fall or stay asleep, can be occasional or a chronic issue that causes constant fatigue. It may result from factors like genetics, irregular sleep schedules, stimulants, alcohol, drug use, or high stress levels. Environmental factors, sedentary lifestyles, and excessive light exposure, especially from screens before bed, can also contribute.\nKleine-Levin syndrome:\nKleine-Levin syndrome, a rare condition primarily affecting young men, causes recurrent episodes of excessive sleepiness that can last days to months and be severely debilitating. These episodes often disrupt daily life and school, with symptoms including hallucinations, hypersexual or compulsive behaviors, binge eating, and mood or cognitive disturbances.\nNarcolepsy\n:\nNarcolepsy disrupts the body's ability to regulate sleep, causing sudden sleep attacks during the day and wakefulness elements during sleep. Key symptoms include cataplexy, a sudden loss of muscle control triggered by emotions, and vivid hallucinations during sleep transitions. Sleep paralysis, frequent nighttime awakenings, and performing actions during sleep attacks without memory of them are also common.\nRestless leg syndrome\n(RLS):\nDisorders causing excessive movements during sleep, like RLS, can disrupt sleep and lead to daytime fatigue. RLS creates an uncomfortable sensation in the legs and an urge to move, typically worsening in the evening or when lying down. Movement temporarily relieves the discomfort but can interfere with restful sleep.\nPeriodic limb movement syndrome\n(PLMS):\nThis condition related to RLS involves sudden jerking movements that occur during sleep. These may be repetitive, disturbing your sleep and potentially that of your bed partner.\nSleep apnea\n:\nSleep apnea causes repeated pauses in breathing during sleep, often followed by loud snorts or gasps that disrupt sleep cycles. These interruptions shift you into lighter sleep stages, leaving you tired even if you don't recall waking. Symptoms include snoring, morning dry mouth or headaches, teeth grinding, sexual dysfunction, and frequent nighttime urination.\nWarning: Risk of Fatal Complications\nSleep apnea puts a strain on your heart. It can lead to high blood pressure, cardiomyopathy (enlarged muscle tissue in the heart), heart failure, heart attack, and stroke. This makes proper diagnosis and treatment of sleep apnea especially important.\nMedications That Cause Drowsiness\nDrowsiness and fatigue are common side effects of medications. If you have daytime tiredness, your healthcare provider will likely look into what medications you're taking. Drugs that can make you tired include:\nAnalgesics:\nPainkillers including opioids such as Vicodin (hydrocodone-acetaminophen), OxyContin (oxycodone)\nAntiseizure medications (ASMs):\nSeizure prevention drugs such as Neurontin (gabapentin) and Lyrica (pregabalin)\nAntidepressants:\nTricyclics and SSRIs\/SNRIs including amitriptyline, Prozac (fluoxetine), Cymbalta (duloxetine)\nAntiemetics:\nDrugs for nausea, vomiting, and motion sickness such as Dramamine (dimenhydrinate), Zyprexa (olanzapine), Reglan (metoclopramide)\nAntihistamines:\nAllergy medications including Zyrtec (cetirizine), Claritin (loratadine), Benadryl (diphenhydramine)\nAntipsychotics:\nDrugs for schizophrenia, psychosis in bipolar disorder, depression, and\nAlzheimer's diseas\ne including\nAbilify (aripiprazole)\n, Risperdal (risperidone), Seroquel (quetiapine)\nBenzodiazepines:\nTranquilizers and sedatives such as Librium (chlordiazepoxide), Valium (diazepam)\nBlood pressure drugs:\nDiuretics, ARBs, calcium channel blockers, beta-blockers including Lasix (furosemide), Avapro (irbesartan), verapamil HCL, Toprol-XL (metoprolol succinate)\nMuscle relaxants:\nIncluding Soma (carisoprodol), Lorzone (chlorzoxazone), Amrix (cyclobenzaprine)\nSedatives:\nNon-benzodiazepine sedative\/hypnotics such as Ambien (zolpidem), Sonata (zaleplon), Lunesta (eszopiclone)\nStatins:\nEspecially fat-soluble drugs including Lipitor (atorvastatin), lovastatin, Vytorin (ezetimibe\/simvastatin), Zocor (simvastatin)\nSteroids:\nUsed for inflammation, allergies, skin diseases, certain cancers, and after organ transplants. Some may cause insomnia, including prednisolone, methylprednisolone, and dexamethasone.\n33 Sources\nVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our\neditorial process\nto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.\nSejbuk M, Mirończuk-Chodakowska I, Witkowska AM.\nSleep quality: A narrative review on nutrition, stimulants, and physical activity as important factors\n.\nNutrients\n. 2022;14(9):1912. doi:10.3390\/nu14091912\nHarvard Health Publishing.\nFight fatigue with fluids\n.\nNational Institutes of Health, National Institute on Aging.\nFatigue in older adults\n.\nHartescu I, Morgan K, Stevinson CD.\nIncreased physical activity improves sleep and mood outcomes in inactive people with insomnia: A randomized controlled trial\n. \nJ Sleep Res\n. 2015;24(5):526-534. doi:10.1111\/jsr.12297\nNational Institutes of Health, U.S. National Library of Medicine: MedlinePlus.\nAre you getting too much exercise?\nAmerican Psychological Association.\nStress and sleep\n.\nSin NL, Wen JH, Klaiber P, Buxton OM, Almeida DM. \nSleep duration and affective reactivity to stressors and positive events in daily life\n. \nHealth Psychol\n. 2020; doi:10.1037\/hea0001033\nUniversity of Pennsylvania. Penn Medicine.\nWhat Is Anemia?\nZielinski MR, Systrom DM, Rose NR.\nFatigue, sleep, and autoimmune and related disorders\n. \nFront Immunol\n. 2019;10:1827. doi:10.3389\/fimmu.2019.01827\nAmerican Cancer Society.\nWhat is fatigue or weakness?\nSotzny F, Blanco J, Capelli E, et al.\nMyalgic encephalomyelitis\/chronic fatigue syndrome - Evidence for an autoimmune disease\n. \nAutoimmun Rev\n. 2018;17(6):601-609. doi:10.1016\/j.autrev.2018.01.009\nGoërtz YMJ, Spruit MA, Van 't Hul AJ, et al.\nFatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation\n. \nTher Adv Respir Dis\n. 2019;13:1753466619878128. doi:10.1177\/1753466619878128\nCorfield EC, Martin NG, Nyholt DR.\nCo-occurrence and symptomatology of fatigue and depression\n. \nCompr Psychiatry\n. 2016;71:1-10. doi:10.1016\/j.comppsych.2016.08.004\nAllen J, Romay-Tallon R, Brymer KJ, Caruncho HJ, Kalynchuk LE.\nMitochondria and mood: Mitochondrial dysfunction as a key player in the manifestation of depression\n. \nFront Neurosci\n. 2018;12:386. doi:10.3389\/fnins.2018.00386\nKalra S, Sahay R.\nDiabetes fatigue syndrome\n. \nDiabetes Ther\n. 2018;9(4):1421-1429. doi:10.1007\/s13300-018-0453-x\nLittlejohn G, Guymer E.\nKey milestones contributing to the understanding of the mechanisms underlying fibromyalgia\n. \nBiomedicines\n. 2020;8(7):223. doi:10.3390\/biomedicines8070223\nWostyn P.\nCOVID-19 and chronic fatigue syndrome: Is the worst yet to come?\n. \nMed Hypotheses\n. 2021;146:110469. doi:10.1016\/j.mehy.2020.110469\nKerr JR.\nEpstein-Barr virus (EBV) reactivation and therapeutic inhibitors\n. \nJ Clin Pathol\n. 2019;72(10):651-658. doi:10.1136\/jclinpath-2019-205822\nPasta A, Formisano E, Calabrese F, et al.\nFood intolerances, food allergies, and IBS: Lights and shadows\n.\nNutrients\n. 2024;16(2):265. doi:10.3390\/nu16020265\nNational Institute of Diabetes and Digestive and Kidney Diseases.\nAnemia in chronic kidney disease\n.\nTaylor-Swanson L, Wong AE, Pincus D, et al.\nThe dynamics of stress and fatigue across menopause: Attractors, coupling, and resilience\n. \nMenopause\n. 2018;25(4):380-390. doi:10.1097\/GME.0000000000001025\nBai G, Korfage IJ, Groen EH, Jaddoe VW, Mautner E, Raat H.\nAssociations between Nausea, Vomiting, Fatigue and Health-Related Quality of Life of Women in Early Pregnancy: The Generation R Study\n. PLoS One. 2016 Nov 4;11(11):e0166133. doi: 10.1371\/journal.pone.0166133\nHarvard Medical School, Harvard Health Publishing.\nThe lowdown on thyroid slowdown\n.\nAmerican Thyroid Association.\nHyperthyroidism\n.\nHarvard Medical School, Harvard Health Publishing.\n5 overlooked symptoms that may signal heart trouble\n.\nNational Institutes of Health, National Heart, Lung, and Blood Institute.\nCircadian rhythm disorders\n.\nNational Institutes of Health, National Heart, Lung, and Blood Institute.\nInsomnia\n.\nde Oliveira MM, Conti C, Prado GF.\nPharmacological treatment for Kleine-Levin syndrome\n. \nCochrane Database Syst Rev\n. 2016;2016(5):CD006685. doi:10.1002\/14651858.CD006685.pub4\nNational Organization for Rare Disorders.\nNarcolepsy\n.\nNational Institute of Neurological Disorders and Stroke.\nRestless legs syndrome\n.\nMount Sinai.\nRestless leg syndrome and related disorders\n.\nRaheem OA, Orosco RK, Davidson TM, Lakin C.\nClinical predictors of nocturia in the sleep apnea population\n.\nUrol Ann.\n2014;6(1):31-5. doi:10.4103\/0974-7796.127019\nHarvard Medical School, Harvard Health Publishing.\nWhat to do when medication makes you sleepy\n.\nBy\nBrandon Peters, MD\nDr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine.\nWas this page helpful?\nThanks for your feedback!\nWhat is your feedback?","attrs_markdown":"[Skip to content](https:\/\/www.verywellhealth.com\/reasons-why-you-feel-sleepy-3014818#skip-to-content)\n\nMenu\n\n- [Health A-Z](https:\/\/www.verywellhealth.com\/health-a-z-4014770)\n  - 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Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment.\n\nⒸ 2026 People Inc. — All rights reserved\n\n# Why Am I Always Tired?\nBy [Brandon Peters, MD](https:\/\/www.verywellhealth.com\/brandon-peters-md-3014640)\n\nUpdated on March 12, 2026\n\nMedically reviewed by  [Sanja Jelic, MD](https:\/\/www.verywellhealth.com\/sanja-jelic-md-4685032)\n\nTable of Contents\n\nView All\n\nTable of Contents\n\n- [Lifestyle Factors](https:\/\/www.verywellhealth.com\/reasons-why-you-feel-sleepy-3014818#toc-everyday-habits-that-can-make-you-tired)\n- [Medical Causes](https:\/\/www.verywellhealth.com\/reasons-why-you-feel-sleepy-3014818#toc-could-a-health-condition-be-draining-your-energy)\n- [Sleep Disorders](https:\/\/www.verywellhealth.com\/reasons-why-you-feel-sleepy-3014818#toc-how-sleep-disorders-affect-your-energy-levels)\n- [Medications](https:\/\/www.verywellhealth.com\/reasons-why-you-feel-sleepy-3014818#toc-medications-that-cause-drowsiness)\n\n### Key Takeaways\n- Fatigue can be caused by medical conditions like sleep apnea, diabetes, or thyroid disease.\n- Poor sleep habits, such as not getting enough sleep or having an uncomfortable sleeping environment, can make you tired.\n- Lifestyle choices, such as unhealthy diet, dehydration, and lack of exercise, can decrease your energy levels.\n\nThe causes of constant tiredness and fatigue can stem from various factors that affect your energy levels throughout the day. These causes typically fall into four categories: lifestyle factors, medical conditions, sleep disorders, and mental health issues.\n\nVerywell \/ Cindy Chung\n\n1:39\n\n### Click Play to Learn What You Can Do to Feel Less Tired\n\nThis video has been medically reviewed by [Chris Vincent, MD](https:\/\/www.verywellhealth.com\/chris-vincent-md-4774437).\n\n## Everyday Habits That Can Make You Tired\nYour daily habits can significantly affect how alert and energetic you feel throughout the day. Consider discussing the following factors with your healthcare provider:\n\n- **Diet:** Your body gets energy from food. An unbalanced diet or skipping meals can make you feel tired. Diet-related causes of fatigue include deficiencies in zinc, vitamin B12, or vitamin D, blood sugar changes, excessive alcohol, and too much caffeine.\n- [**Dehydration**](https:\/\/www.verywellhealth.com\/diseases-that-cause-dehydration-in-adults-8679450)**:** Dehydration occurs when you lose more fluids than you take in. Since water makes up 50% to 60% of your body weight, sweating, urination, heat, or illness can quickly deplete your hydration levels. While drinking eight 8-ounce glasses of water daily is a common guideline, very pale yellow or clear urine generally indicates proper hydration.\n- **Poor sleep habits:** Daytime fatigue may result from not getting enough quality sleep. Poor habits like sleeping in a noisy or uncomfortable environment, skipping a bedtime routine, exercising too close to bedtime, or napping late in the day can disrupt your rest. Additionally, not meeting the sleep needs for your age (eight to nine hours a night for adults ages 18 to 60) can leave you feeling tired.\n- [**Inactive lifestyle**](https:\/\/www.verywellhealth.com\/sitting-down-8629219)**:** Sitting for long periods can lead to restless and poor-quality sleep. Engaging in regular physical activity can improve your sleep and mental well-being. One study found that participants who exercised for 150 minutes a week experienced less insomnia, depression, and anxiety compared to those who were less active..\n- **Overexertion:** Overexerting yourself through excessive exercise or other activities can leave your body too depleted to recover. This can lead to fatigue, poor sleep, and low motivation. Symptoms of overexertion may include mood swings, sore limbs, frequent illness, and a decline in performance at work or home.\n- [**Stress**](https:\/\/www.verywellhealth.com\/psychological-stress-5205714)**:** Stress can disrupt your sleep, and poor sleep can increase stress and fatigue. A survey found 43% of adults lost sleep due to stress, and 37% reported feeling tired because of it. Getting quality sleep helps maintain a positive mood during stressful times and increases joy from good experiences.\n## Could a Health Condition Be Draining Your Energy?\nFeeling fatigued, weak, or sleepy can be symptoms of various medical conditions that impact your energy. Daytime sleepiness may be linked to these underlying causes:\n\n- [**Anemia**](https:\/\/www.verywellhealth.com\/anemia-symptoms-4628300)**:** Anemia is a condition in which your body has fewer red blood cells or they don't function properly, reducing the blood's ability to deliver oxygen to your organs. This can cause symptoms like fatigue, headaches, difficulty concentrating, irritability, and numbness in the hands and feet. The most common type is iron-deficiency anemia, but other causes include inherited disorders, chronic illnesses, and pregnancy.\n- **Autoimmune disease:** Autoimmune diseases occur when your immune system mistakenly attacks your own body, causing tissue damage and chronic inflammation. Conditions like rheumatoid arthritis, lupus, multiple sclerosis, and [inflammatory bowel disease](https:\/\/www.verywellhealth.com\/ibd-crohns-colitis-overview-4581950) can lead to fatigue and disrupt your metabolism, nervous system, and sleep patterns. They may also cause imbalances in cytokines, proteins that regulate inflammation, mood, and sleep.\n- **Cancer:** More than 80% of people with cancer experience [cancer-related fatigue](https:\/\/www.verywellhealth.com\/is-fatigue-a-symptom-of-cancer-514435), which often doesn't improve with rest and can be an early sign of the disease. Fatigue can result from low blood counts, disturbed electrolytes, altered hormone or cytokine levels, and changes in cell function caused by cancer. Treatments like chemotherapy, immunotherapy, and radiation can also contribute to fatigue.\n- [**Chronic fatigue syndrome**](https:\/\/www.verywellhealth.com\/understanding-chronic-fatigue-syndrome-4158459)**:** Chronic fatigue syndrome (ME\/CFS) causes extreme fatigue that worsens with minimal exertion, doesn't improve with rest, and often includes flu-like symptoms and cognitive issues like \"brain fog.\" The exact cause is unknown, but it may be linked to infections, chronic stress, autoimmune responses, or cytokine-related inflammation.\n- [**Chronic obstructive pulmonary disease**](https:\/\/www.verywellhealth.com\/copd-4014741) **(COPD):** This chronic disease causes wheezing, shortness of breath, and extra mucus, making it hard to breathe. Fatigue is common in COPD, but it may not always be directly linked to breathing difficulties. The disease progresses over time, and it is especially common in current or former smokers.\n- **Depression:** This mood disorder causes sadness, loss of interest, and physical symptoms like fatigue. Daytime sleepiness may result from insomnia or other sleep problems often linked to depression, and fatigue may serve as an early warning sign. Biochemical similarities between depression and ME\/CFS might explain fatigue as a shared symptom.\n- [**Diabetes**](https:\/\/www.verywellhealth.com\/undiagnosed-diabetes-5179188)**:** Diabetes fatigue syndrome refers to persistent fatigue experienced by people with diabetes. Possible causes include low blood sugar, hormonal imbalances, treatment side effects, overlapping conditions, and lifestyle factors like diet.\n- [**Fibromyalgia**](https:\/\/www.verywellhealth.com\/fibromyalgia-7369351)**:** Fibromyalgia is a chronic pain condition. It's caused by dysfunction in the central nervous system, which heightens sensitivity and turns harmless sensations into pain (allodynia). Fatigue is also a key symptom of fibromyalgia. This fatigue may be due to biochemical changes, inflammation, sleep disorders, and sleep disruptions.\n- **Heart disease:** If you have fatigue that's new and constant, it may be an early warning sign of heart failure or, less often, [coronary artery disease](https:\/\/www.verywellhealth.com\/heart-disease-7481236). These conditions limit the amount of oxygen-rich blood that gets to your muscles or to the heart itself. Your heart and brain need oxygen. When you have heart disease, your body limits the blood sent to less important parts like the limbs, leading to reduced energy and fatigue.\n- **Infections:** Fatigue is common during and after infectious illnesses like COVID-19, influenza, mononucleosis, and [Lyme disease](https:\/\/www.verywellhealth.com\/lyme-disease-7151644). While tiredness often resolves as the illness clears, some people experience lingering fatigue, known as post-viral fatigue or, [in the case of COVID-19, long COVID](https:\/\/www.verywellhealth.com\/nicotine-patches-long-covid-treatment-8705089). Researchers are exploring links between these persistent symptoms and conditions like ME\/CFS, especially for viruses like Epstein-Barr, which can reactivate and contribute to fatigue and autoimmune diseases.\n- [**Food allergies and intolerances**](https:\/\/www.verywellhealth.com\/most-common-food-sensitivities-1944845)**:** Food allergies and intolerances can cause fatigue by triggering immune responses or gastrointestinal distress that depletes energy levels. Reactions to allergens, such as dairy, gluten, or nuts, may lead to inflammation, poor nutrient absorption, or disrupted sleep. Chronic exposure to problematic foods can worsen fatigue over time, especially if the underlying issue goes unaddressed.\n- [**Kidney disease**](https:\/\/www.verywellhealth.com\/acute-vs-chronic-kidney-disease-5221287)**:** Kidney disease can cause fatigue due to the buildup of toxins in the blood when the kidneys are not functioning properly. This can lead to anemia, as the kidneys produce less erythropoietin, a hormone essential for red blood cell production. Electrolyte imbalances and reduced nutrient absorption may also contribute to low energy levels.\n- [**Menopause**](https:\/\/www.verywellhealth.com\/side-effects-of-menopause-5217701)**:** The transition to menopause, including perimenopause and the early post-menopausal stage, often brings fatigue along with symptoms like hot flashes, night sweats, and mood swings. Fatigue may stem from sleep disruptions, hormonal changes, aging, or stress.\n- [**Pregnancy**](https:\/\/www.verywellhealth.com\/pregnancy-facts-and-statistics-5324188)**:** Pregnancy places extra demands on the body, often causing fatigue, especially during the first and third trimesters. Factors contributing to this tiredness include the energy required to support the baby, hormonal changes, low blood sugar or pressure, and disrupted sleep. Stress and digestive changes can also play a role in pregnancy-related exhaustion.\n- [**Thyroid disease**](https:\/\/www.verywellhealth.com\/hypothyroidism-hyperthyroidism-5180646)**:** Thyroid hormone imbalances, whether high (hyperthyroidism) or low (hypothyroidism), can cause fatigue due to their effects on metabolism. Hyperthyroidism speeds up bodily processes, leading to symptoms like anxiety, sleep disruption, and eventual exhaustion as energy reserves deplete, while hypothyroidism slows everything down, causing fatigue alongside weight gain, depression, and memory problems.\n\n### Recognizing a Heart Attack\nA heart attack requires immediate medical attention. Call 9-1-1 if you or someone else suddenly experiences:\n\n- Chest pain or pressure, which can also be in the upper abdomen\n- Pain that spreads to the jaw, neck, back, arms, or stomach\n- Shortness of breath\n- Dizziness or fainting\n- Nausea or vomiting\n- Extreme fatigue\n## How Sleep Disorders Affect Your Energy Levels\nVarious circadian rhythm disorders can leave you [feeling too sleepy during the day](https:\/\/www.verywellhealth.com\/why-am-i-sleepy-after-eating-lunch-3014827). The circadian rhythm is your body's natural clock. It helps to coordinate your activities based on when it's light and dark in your environment. If your internal timing is misaligned, you may find yourself with excessive daytime sleepiness.\n\nSix common circadian rhythm disorders include:\n\n- **Advanced sleep phase syndrome:** The distinguishing feature is falling asleep and waking up earlier than you want, usually by about three hours.\n- **Delayed sleep phase syndrome:** This causes difficulty falling asleep and makes it extremely hard to wake up.\n- **Irregular sleep-wake rhythm:** This occurs when the circadian rhythm becomes completely disconnected from the natural day-night cycle. Sleep is fragmented, with short spells scattered throughout the day.\n- **Jet lag:** A temporary rhythm disorder associated with travel across several time zones. To adjust, it may take one day for every time zone you cross.\n- **Non-entrained (non-24) disorder:** This usually occurs in visually impaired people. The sleep cycle is typically a little longer than average and thus becomes more out of sync every day.\n- **Shift-work sleep disorder:** Poor sleep is caused by working at night and sleeping during the day. This can lead to increased accidents and possibly a higher risk of some forms of cancer.\n\nOther sleep disorders that can result in constant tiredness or fatigue include:\n\n- [**Insomnia**](https:\/\/www.verywellhealth.com\/what-is-insomnia-the-features-symptoms-and-causes-3014805)**:** Insomnia, which makes it hard to fall or stay asleep, can be occasional or a chronic issue that causes constant fatigue. It may result from factors like genetics, irregular sleep schedules, stimulants, alcohol, drug use, or high stress levels. Environmental factors, sedentary lifestyles, and excessive light exposure, especially from screens before bed, can also contribute.\n- **Kleine-Levin syndrome:** Kleine-Levin syndrome, a rare condition primarily affecting young men, causes recurrent episodes of excessive sleepiness that can last days to months and be severely debilitating. These episodes often disrupt daily life and school, with symptoms including hallucinations, hypersexual or compulsive behaviors, binge eating, and mood or cognitive disturbances.\n- [**Narcolepsy**](https:\/\/www.verywellhealth.com\/restless-sleep-symptoms-causes-and-treatment-5649715)**:** Narcolepsy disrupts the body's ability to regulate sleep, causing sudden sleep attacks during the day and wakefulness elements during sleep. Key symptoms include cataplexy, a sudden loss of muscle control triggered by emotions, and vivid hallucinations during sleep transitions. Sleep paralysis, frequent nighttime awakenings, and performing actions during sleep attacks without memory of them are also common.\n- [**Restless leg syndrome**](https:\/\/www.verywellhealth.com\/restless-leg-syndrome-1746081) **(RLS):** Disorders causing excessive movements during sleep, like RLS, can disrupt sleep and lead to daytime fatigue. RLS creates an uncomfortable sensation in the legs and an urge to move, typically worsening in the evening or when lying down. Movement temporarily relieves the discomfort but can interfere with restful sleep.\n- [**Periodic limb movement syndrome**](https:\/\/www.verywellhealth.com\/types-of-sleep-disorders-8778367) **(PLMS):** This condition related to RLS involves sudden jerking movements that occur during sleep. These may be repetitive, disturbing your sleep and potentially that of your bed partner.\n- [**Sleep apnea**](https:\/\/www.verywellhealth.com\/effects-of-sleep-apnea-5215939)**:** Sleep apnea causes repeated pauses in breathing during sleep, often followed by loud snorts or gasps that disrupt sleep cycles. These interruptions shift you into lighter sleep stages, leaving you tired even if you don't recall waking. Symptoms include snoring, morning dry mouth or headaches, teeth grinding, sexual dysfunction, and frequent nighttime urination.\n\n### Warning: Risk of Fatal Complications\nSleep apnea puts a strain on your heart. It can lead to high blood pressure, cardiomyopathy (enlarged muscle tissue in the heart), heart failure, heart attack, and stroke. This makes proper diagnosis and treatment of sleep apnea especially important.\n## Medications That Cause Drowsiness\nDrowsiness and fatigue are common side effects of medications. If you have daytime tiredness, your healthcare provider will likely look into what medications you're taking. Drugs that can make you tired include:\n\n- **Analgesics:** Painkillers including opioids such as Vicodin (hydrocodone-acetaminophen), OxyContin (oxycodone)\n- **Antiseizure medications (ASMs):** Seizure prevention drugs such as Neurontin (gabapentin) and Lyrica (pregabalin)\n- **Antidepressants:** Tricyclics and SSRIs\/SNRIs including amitriptyline, Prozac (fluoxetine), Cymbalta (duloxetine)\n- **Antiemetics:** Drugs for nausea, vomiting, and motion sickness such as Dramamine (dimenhydrinate), Zyprexa (olanzapine), Reglan (metoclopramide)\n- **Antihistamines:** Allergy medications including Zyrtec (cetirizine), Claritin (loratadine), Benadryl (diphenhydramine)\n- **Antipsychotics:** Drugs for schizophrenia, psychosis in bipolar disorder, depression, and [Alzheimer's diseas](https:\/\/www.verywellhealth.com\/alzheimers-disease-7111202)e including [Abilify (aripiprazole)](https:\/\/www.verywellhealth.com\/how-long-does-it-take-for-abilify-to-work-8553110), Risperdal (risperidone), Seroquel (quetiapine)\n- **Benzodiazepines:** Tranquilizers and sedatives such as Librium (chlordiazepoxide), Valium (diazepam)\n- **Blood pressure drugs:** Diuretics, ARBs, calcium channel blockers, beta-blockers including Lasix (furosemide), Avapro (irbesartan), verapamil HCL, Toprol-XL (metoprolol succinate)\n- **Muscle relaxants:** Including Soma (carisoprodol), Lorzone (chlorzoxazone), Amrix (cyclobenzaprine)\n- **Sedatives:** Non-benzodiazepine sedative\/hypnotics such as Ambien (zolpidem), Sonata (zaleplon), Lunesta (eszopiclone)\n- **Statins:** Especially fat-soluble drugs including Lipitor (atorvastatin), lovastatin, Vytorin (ezetimibe\/simvastatin), Zocor (simvastatin)\n- **Steroids:** Used for inflammation, allergies, skin diseases, certain cancers, and after organ transplants. Some may cause insomnia, including prednisolone, methylprednisolone, and dexamethasone.\n\nRead more:\n\n- [Health A-Z](https:\/\/www.verywellhealth.com\/health-a-z-4014770)\n- [Sleep Disorders](https:\/\/www.verywellhealth.com\/sleep-disorders-4014648)\n- [Insomnia & More Disorders](https:\/\/www.verywellhealth.com\/insomnia-and-more-sleep-disorders-4013520)\n\n33 Sources\n\nVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our [editorial process](https:\/\/www.verywellhealth.com\/verywell-editorial-process-4777042) to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.\n\n1. Sejbuk M, Mirończuk-Chodakowska I, Witkowska AM. [Sleep quality: A narrative review on nutrition, stimulants, and physical activity as important factors](https:\/\/doi.org\/10.3390%2Fnu14091912). *Nutrients*. 2022;14(9):1912. doi:10.3390\/nu14091912\n2. Harvard Health Publishing. 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[Sleep duration and affective reactivity to stressors and positive events in daily life](https:\/\/doi.org\/10.1037\/hea0001033). *Health Psychol*. 2020; doi:10.1037\/hea0001033\n8. University of Pennsylvania. Penn Medicine. [What Is Anemia?](https:\/\/www.pennmedicine.org\/for-patients-and-visitors\/patient-information\/conditions-treated-a-to-z\/anemia)\n9. Zielinski MR, Systrom DM, Rose NR. [Fatigue, sleep, and autoimmune and related disorders](https:\/\/doi.org\/10.3389\/fimmu.2019.01827). *Front Immunol*. 2019;10:1827. doi:10.3389\/fimmu.2019.01827\n10. American Cancer Society. [What is fatigue or weakness?](https:\/\/www.cancer.org\/cancer\/managing-cancer\/side-effects\/fatigue\/what-is-cancer-related-fatigue.html)\n11. Sotzny F, Blanco J, Capelli E, et al. [Myalgic encephalomyelitis\/chronic fatigue syndrome - Evidence for an autoimmune disease](https:\/\/doi.org\/10.1016\/j.autrev.2018.01.009). *Autoimmun Rev*. 2018;17(6):601-609. doi:10.1016\/j.autrev.2018.01.009\n12. 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[Anemia in chronic kidney disease](https:\/\/www.niddk.nih.gov\/health-information\/kidney-disease\/anemia).\n21. Taylor-Swanson L, Wong AE, Pincus D, et al. [The dynamics of stress and fatigue across menopause: Attractors, coupling, and resilience](https:\/\/doi.org\/10.1097\/gme.0000000000001025). *Menopause*. 2018;25(4):380-390. doi:10.1097\/GME.0000000000001025\n22. Bai G, Korfage IJ, Groen EH, Jaddoe VW, Mautner E, Raat H. [Associations between Nausea, Vomiting, Fatigue and Health-Related Quality of Life of Women in Early Pregnancy: The Generation R Study](https:\/\/doi.org\/10.1371%2Fjournal.pone.0166133). PLoS One. 2016 Nov 4;11(11):e0166133. doi: 10.1371\/journal.pone.0166133\n23. Harvard Medical School, Harvard Health Publishing. [The lowdown on thyroid slowdown](https:\/\/www.health.harvard.edu\/newsletter_article\/the-lowdown-on-thyroid-slowdown).\n24. American Thyroid Association. [Hyperthyroidism](https:\/\/www.thyroid.org\/hyperthyroidism\/).\n25. Harvard Medical School, Harvard Health Publishing. [5 overlooked symptoms that may signal heart trouble](https:\/\/www.health.harvard.edu\/heart-health\/5-overlooked-symptoms-that-may-signal-heart-trouble).\n26. National Institutes of Health, National Heart, Lung, and Blood Institute. [Circadian rhythm disorders](https:\/\/www.nhlbi.nih.gov\/health\/circadian-rhythm-disorders).\n27. National Institutes of Health, National Heart, Lung, and Blood Institute. [Insomnia](https:\/\/www.nhlbi.nih.gov\/health\/insomnia).\n28. de Oliveira MM, Conti C, Prado GF. [Pharmacological treatment for Kleine-Levin syndrome](https:\/\/doi.org\/10.1002\/14651858.cd006685.pub4). *Cochrane Database Syst Rev*. 2016;2016(5):CD006685. doi:10.1002\/14651858.CD006685.pub4\n29. National Organization for Rare Disorders. [Narcolepsy](https:\/\/rarediseases.org\/rare-diseases\/narcolepsy\/).\n30. National Institute of Neurological Disorders and Stroke. [Restless legs syndrome](https:\/\/www.ninds.nih.gov\/health-information\/disorders\/restless-legs-syndrome).\n31. Mount Sinai. [Restless leg syndrome and related disorders](https:\/\/www.mountsinai.org\/health-library\/report\/restless-legs-syndrome-and-related-disorders).\n32. Raheem OA, Orosco RK, Davidson TM, Lakin C. [Clinical predictors of nocturia in the sleep apnea population](https:\/\/doi.org\/10.4103\/0974-7796.127019). *Urol Ann.* 2014;6(1):31-5. doi:10.4103\/0974-7796.127019\n33. Harvard Medical School, Harvard Health Publishing. [What to do when medication makes you sleepy](https:\/\/www.health.harvard.edu\/medications\/what-to-do-when-medication-makes-you-sleepy#:~:text=Common%20culprits%20that%20cause%20sleepiness,to%20treat%20high%20blood%20pressure%2C).\n\n![Brandon Peters, M.D.]()\n\n![Brandon Peters, M.D.](https:\/\/www.verywellhealth.com\/thmb\/BbtKTL7wVNFD-4Y2KIj4azA0HpE=\/144x144\/filters:no_upscale\\(\\):max_bytes\\(150000\\):strip_icc\\(\\)\/BrandonPetersMD_1000-5143e542c3084368b1220c4b86ede01c.png)\n\nBy [Brandon Peters, MD](https:\/\/www.verywellhealth.com\/brandon-peters-md-3014640)   \n Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine.\n\n[See Our Editorial Process](https:\/\/www.verywellhealth.com\/verywell-editorial-process-4777042)\n\n[Meet Our Medical Expert Board](https:\/\/www.verywellhealth.com\/meet-our-medical-expert-board-11762003)\n\nShare Feedback\n\nWas this page helpful?\n\nThanks for your 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Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment.\n\nⒸ 2026 People Inc. — All rights reserved\n\nVerywell Health is part of the [People Inc.](https:\/\/www.people.inc\/) publishing family.","attrs_readable_markdown":"### Key Takeaways\n- Fatigue can be caused by medical conditions like sleep apnea, diabetes, or thyroid disease.\n- Poor sleep habits, such as not getting enough sleep or having an uncomfortable sleeping environment, can make you tired.\n- Lifestyle choices, such as unhealthy diet, dehydration, and lack of exercise, can decrease your energy levels.\n\nThe causes of constant tiredness and fatigue can stem from various factors that affect your energy levels throughout the day. These causes typically fall into four categories: lifestyle factors, medical conditions, sleep disorders, and mental health issues.\n\nVerywell \/ Cindy Chung\n\n1:39\n\n### Click Play to Learn What You Can Do to Feel Less Tired\n## Everyday Habits That Can Make You Tired\nYour daily habits can significantly affect how alert and energetic you feel throughout the day. Consider discussing the following factors with your healthcare provider:\n\n- **Diet:** Your body gets energy from food. An unbalanced diet or skipping meals can make you feel tired. Diet-related causes of fatigue include deficiencies in zinc, vitamin B12, or vitamin D, blood sugar changes, excessive alcohol, and too much caffeine.\n- [**Dehydration**](https:\/\/www.verywellhealth.com\/diseases-that-cause-dehydration-in-adults-8679450)**:** Dehydration occurs when you lose more fluids than you take in. Since water makes up 50% to 60% of your body weight, sweating, urination, heat, or illness can quickly deplete your hydration levels. While drinking eight 8-ounce glasses of water daily is a common guideline, very pale yellow or clear urine generally indicates proper hydration.\n- **Poor sleep habits:** Daytime fatigue may result from not getting enough quality sleep. Poor habits like sleeping in a noisy or uncomfortable environment, skipping a bedtime routine, exercising too close to bedtime, or napping late in the day can disrupt your rest. Additionally, not meeting the sleep needs for your age (eight to nine hours a night for adults ages 18 to 60) can leave you feeling tired.\n- [**Inactive lifestyle**](https:\/\/www.verywellhealth.com\/sitting-down-8629219)**:** Sitting for long periods can lead to restless and poor-quality sleep. Engaging in regular physical activity can improve your sleep and mental well-being. One study found that participants who exercised for 150 minutes a week experienced less insomnia, depression, and anxiety compared to those who were less active..\n- **Overexertion:** Overexerting yourself through excessive exercise or other activities can leave your body too depleted to recover. This can lead to fatigue, poor sleep, and low motivation. Symptoms of overexertion may include mood swings, sore limbs, frequent illness, and a decline in performance at work or home.\n- [**Stress**](https:\/\/www.verywellhealth.com\/psychological-stress-5205714)**:** Stress can disrupt your sleep, and poor sleep can increase stress and fatigue. A survey found 43% of adults lost sleep due to stress, and 37% reported feeling tired because of it. Getting quality sleep helps maintain a positive mood during stressful times and increases joy from good experiences.\n## Could a Health Condition Be Draining Your Energy?\nFeeling fatigued, weak, or sleepy can be symptoms of various medical conditions that impact your energy. Daytime sleepiness may be linked to these underlying causes:\n\n- [**Anemia**](https:\/\/www.verywellhealth.com\/anemia-symptoms-4628300)**:** Anemia is a condition in which your body has fewer red blood cells or they don't function properly, reducing the blood's ability to deliver oxygen to your organs. This can cause symptoms like fatigue, headaches, difficulty concentrating, irritability, and numbness in the hands and feet. The most common type is iron-deficiency anemia, but other causes include inherited disorders, chronic illnesses, and pregnancy.\n- **Autoimmune disease:** Autoimmune diseases occur when your immune system mistakenly attacks your own body, causing tissue damage and chronic inflammation. Conditions like rheumatoid arthritis, lupus, multiple sclerosis, and [inflammatory bowel disease](https:\/\/www.verywellhealth.com\/ibd-crohns-colitis-overview-4581950) can lead to fatigue and disrupt your metabolism, nervous system, and sleep patterns. They may also cause imbalances in cytokines, proteins that regulate inflammation, mood, and sleep.\n- **Cancer:** More than 80% of people with cancer experience [cancer-related fatigue](https:\/\/www.verywellhealth.com\/is-fatigue-a-symptom-of-cancer-514435), which often doesn't improve with rest and can be an early sign of the disease. Fatigue can result from low blood counts, disturbed electrolytes, altered hormone or cytokine levels, and changes in cell function caused by cancer. Treatments like chemotherapy, immunotherapy, and radiation can also contribute to fatigue.\n- [**Chronic fatigue syndrome**](https:\/\/www.verywellhealth.com\/understanding-chronic-fatigue-syndrome-4158459)**:** Chronic fatigue syndrome (ME\/CFS) causes extreme fatigue that worsens with minimal exertion, doesn't improve with rest, and often includes flu-like symptoms and cognitive issues like \"brain fog.\" The exact cause is unknown, but it may be linked to infections, chronic stress, autoimmune responses, or cytokine-related inflammation.\n- [**Chronic obstructive pulmonary disease**](https:\/\/www.verywellhealth.com\/copd-4014741) **(COPD):** This chronic disease causes wheezing, shortness of breath, and extra mucus, making it hard to breathe. Fatigue is common in COPD, but it may not always be directly linked to breathing difficulties. The disease progresses over time, and it is especially common in current or former smokers.\n- **Depression:** This mood disorder causes sadness, loss of interest, and physical symptoms like fatigue. Daytime sleepiness may result from insomnia or other sleep problems often linked to depression, and fatigue may serve as an early warning sign. Biochemical similarities between depression and ME\/CFS might explain fatigue as a shared symptom.\n- [**Diabetes**](https:\/\/www.verywellhealth.com\/undiagnosed-diabetes-5179188)**:** Diabetes fatigue syndrome refers to persistent fatigue experienced by people with diabetes. Possible causes include low blood sugar, hormonal imbalances, treatment side effects, overlapping conditions, and lifestyle factors like diet.\n- [**Fibromyalgia**](https:\/\/www.verywellhealth.com\/fibromyalgia-7369351)**:** Fibromyalgia is a chronic pain condition. It's caused by dysfunction in the central nervous system, which heightens sensitivity and turns harmless sensations into pain (allodynia). Fatigue is also a key symptom of fibromyalgia. This fatigue may be due to biochemical changes, inflammation, sleep disorders, and sleep disruptions.\n- **Heart disease:** If you have fatigue that's new and constant, it may be an early warning sign of heart failure or, less often, [coronary artery disease](https:\/\/www.verywellhealth.com\/heart-disease-7481236). These conditions limit the amount of oxygen-rich blood that gets to your muscles or to the heart itself. Your heart and brain need oxygen. When you have heart disease, your body limits the blood sent to less important parts like the limbs, leading to reduced energy and fatigue.\n- **Infections:** Fatigue is common during and after infectious illnesses like COVID-19, influenza, mononucleosis, and [Lyme disease](https:\/\/www.verywellhealth.com\/lyme-disease-7151644). While tiredness often resolves as the illness clears, some people experience lingering fatigue, known as post-viral fatigue or, [in the case of COVID-19, long COVID](https:\/\/www.verywellhealth.com\/nicotine-patches-long-covid-treatment-8705089). Researchers are exploring links between these persistent symptoms and conditions like ME\/CFS, especially for viruses like Epstein-Barr, which can reactivate and contribute to fatigue and autoimmune diseases.\n- [**Food allergies and intolerances**](https:\/\/www.verywellhealth.com\/most-common-food-sensitivities-1944845)**:** Food allergies and intolerances can cause fatigue by triggering immune responses or gastrointestinal distress that depletes energy levels. Reactions to allergens, such as dairy, gluten, or nuts, may lead to inflammation, poor nutrient absorption, or disrupted sleep. Chronic exposure to problematic foods can worsen fatigue over time, especially if the underlying issue goes unaddressed.\n- [**Kidney disease**](https:\/\/www.verywellhealth.com\/acute-vs-chronic-kidney-disease-5221287)**:** Kidney disease can cause fatigue due to the buildup of toxins in the blood when the kidneys are not functioning properly. This can lead to anemia, as the kidneys produce less erythropoietin, a hormone essential for red blood cell production. Electrolyte imbalances and reduced nutrient absorption may also contribute to low energy levels.\n- [**Menopause**](https:\/\/www.verywellhealth.com\/side-effects-of-menopause-5217701)**:** The transition to menopause, including perimenopause and the early post-menopausal stage, often brings fatigue along with symptoms like hot flashes, night sweats, and mood swings. Fatigue may stem from sleep disruptions, hormonal changes, aging, or stress.\n- [**Pregnancy**](https:\/\/www.verywellhealth.com\/pregnancy-facts-and-statistics-5324188)**:** Pregnancy places extra demands on the body, often causing fatigue, especially during the first and third trimesters. Factors contributing to this tiredness include the energy required to support the baby, hormonal changes, low blood sugar or pressure, and disrupted sleep. Stress and digestive changes can also play a role in pregnancy-related exhaustion.\n- [**Thyroid disease**](https:\/\/www.verywellhealth.com\/hypothyroidism-hyperthyroidism-5180646)**:** Thyroid hormone imbalances, whether high (hyperthyroidism) or low (hypothyroidism), can cause fatigue due to their effects on metabolism. Hyperthyroidism speeds up bodily processes, leading to symptoms like anxiety, sleep disruption, and eventual exhaustion as energy reserves deplete, while hypothyroidism slows everything down, causing fatigue alongside weight gain, depression, and memory problems.\n\n### Recognizing a Heart Attack\nA heart attack requires immediate medical attention. Call 9-1-1 if you or someone else suddenly experiences:\n\n- Chest pain or pressure, which can also be in the upper abdomen\n- Pain that spreads to the jaw, neck, back, arms, or stomach\n- Shortness of breath\n- Dizziness or fainting\n- Nausea or vomiting\n- Extreme fatigue\n## How Sleep Disorders Affect Your Energy Levels\nVarious circadian rhythm disorders can leave you [feeling too sleepy during the day](https:\/\/www.verywellhealth.com\/why-am-i-sleepy-after-eating-lunch-3014827). The circadian rhythm is your body's natural clock. It helps to coordinate your activities based on when it's light and dark in your environment. If your internal timing is misaligned, you may find yourself with excessive daytime sleepiness.\n\nSix common circadian rhythm disorders include:\n\n- **Advanced sleep phase syndrome:** The distinguishing feature is falling asleep and waking up earlier than you want, usually by about three hours.\n- **Delayed sleep phase syndrome:** This causes difficulty falling asleep and makes it extremely hard to wake up.\n- **Irregular sleep-wake rhythm:** This occurs when the circadian rhythm becomes completely disconnected from the natural day-night cycle. Sleep is fragmented, with short spells scattered throughout the day.\n- **Jet lag:** A temporary rhythm disorder associated with travel across several time zones. To adjust, it may take one day for every time zone you cross.\n- **Non-entrained (non-24) disorder:** This usually occurs in visually impaired people. The sleep cycle is typically a little longer than average and thus becomes more out of sync every day.\n- **Shift-work sleep disorder:** Poor sleep is caused by working at night and sleeping during the day. This can lead to increased accidents and possibly a higher risk of some forms of cancer.\n\nOther sleep disorders that can result in constant tiredness or fatigue include:\n\n- [**Insomnia**](https:\/\/www.verywellhealth.com\/what-is-insomnia-the-features-symptoms-and-causes-3014805)**:** Insomnia, which makes it hard to fall or stay asleep, can be occasional or a chronic issue that causes constant fatigue. It may result from factors like genetics, irregular sleep schedules, stimulants, alcohol, drug use, or high stress levels. Environmental factors, sedentary lifestyles, and excessive light exposure, especially from screens before bed, can also contribute.\n- **Kleine-Levin syndrome:** Kleine-Levin syndrome, a rare condition primarily affecting young men, causes recurrent episodes of excessive sleepiness that can last days to months and be severely debilitating. These episodes often disrupt daily life and school, with symptoms including hallucinations, hypersexual or compulsive behaviors, binge eating, and mood or cognitive disturbances.\n- [**Narcolepsy**](https:\/\/www.verywellhealth.com\/restless-sleep-symptoms-causes-and-treatment-5649715)**:** Narcolepsy disrupts the body's ability to regulate sleep, causing sudden sleep attacks during the day and wakefulness elements during sleep. Key symptoms include cataplexy, a sudden loss of muscle control triggered by emotions, and vivid hallucinations during sleep transitions. Sleep paralysis, frequent nighttime awakenings, and performing actions during sleep attacks without memory of them are also common.\n- [**Restless leg syndrome**](https:\/\/www.verywellhealth.com\/restless-leg-syndrome-1746081) **(RLS):** Disorders causing excessive movements during sleep, like RLS, can disrupt sleep and lead to daytime fatigue. RLS creates an uncomfortable sensation in the legs and an urge to move, typically worsening in the evening or when lying down. Movement temporarily relieves the discomfort but can interfere with restful sleep.\n- [**Periodic limb movement syndrome**](https:\/\/www.verywellhealth.com\/types-of-sleep-disorders-8778367) **(PLMS):** This condition related to RLS involves sudden jerking movements that occur during sleep. These may be repetitive, disturbing your sleep and potentially that of your bed partner.\n- [**Sleep apnea**](https:\/\/www.verywellhealth.com\/effects-of-sleep-apnea-5215939)**:** Sleep apnea causes repeated pauses in breathing during sleep, often followed by loud snorts or gasps that disrupt sleep cycles. These interruptions shift you into lighter sleep stages, leaving you tired even if you don't recall waking. Symptoms include snoring, morning dry mouth or headaches, teeth grinding, sexual dysfunction, and frequent nighttime urination.\n\n### Warning: Risk of Fatal Complications\nSleep apnea puts a strain on your heart. It can lead to high blood pressure, cardiomyopathy (enlarged muscle tissue in the heart), heart failure, heart attack, and stroke. This makes proper diagnosis and treatment of sleep apnea especially important.\n## Medications That Cause Drowsiness\nDrowsiness and fatigue are common side effects of medications. If you have daytime tiredness, your healthcare provider will likely look into what medications you're taking. Drugs that can make you tired include:\n\n- **Analgesics:** Painkillers including opioids such as Vicodin (hydrocodone-acetaminophen), OxyContin (oxycodone)\n- **Antiseizure medications (ASMs):** Seizure prevention drugs such as Neurontin (gabapentin) and Lyrica (pregabalin)\n- **Antidepressants:** Tricyclics and SSRIs\/SNRIs including amitriptyline, Prozac (fluoxetine), Cymbalta (duloxetine)\n- **Antiemetics:** Drugs for nausea, vomiting, and motion sickness such as Dramamine (dimenhydrinate), Zyprexa (olanzapine), Reglan (metoclopramide)\n- **Antihistamines:** Allergy medications including Zyrtec (cetirizine), Claritin (loratadine), Benadryl (diphenhydramine)\n- **Antipsychotics:** Drugs for schizophrenia, psychosis in bipolar disorder, depression, and [Alzheimer's diseas](https:\/\/www.verywellhealth.com\/alzheimers-disease-7111202)e including [Abilify (aripiprazole)](https:\/\/www.verywellhealth.com\/how-long-does-it-take-for-abilify-to-work-8553110), Risperdal (risperidone), Seroquel (quetiapine)\n- **Benzodiazepines:** Tranquilizers and sedatives such as Librium (chlordiazepoxide), Valium (diazepam)\n- **Blood pressure drugs:** Diuretics, ARBs, calcium channel blockers, beta-blockers including Lasix (furosemide), Avapro (irbesartan), verapamil HCL, Toprol-XL (metoprolol succinate)\n- **Muscle relaxants:** Including Soma (carisoprodol), Lorzone (chlorzoxazone), Amrix (cyclobenzaprine)\n- **Sedatives:** Non-benzodiazepine sedative\/hypnotics such as Ambien (zolpidem), Sonata (zaleplon), Lunesta (eszopiclone)\n- **Statins:** Especially fat-soluble drugs including Lipitor (atorvastatin), lovastatin, Vytorin (ezetimibe\/simvastatin), Zocor (simvastatin)\n- **Steroids:** Used for inflammation, allergies, skin diseases, certain cancers, and after organ transplants. Some may cause insomnia, including prednisolone, methylprednisolone, and dexamethasone.\n\n33 Sources\n\nVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our [editorial process](https:\/\/www.verywellhealth.com\/verywell-editorial-process-4777042) to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.\n\n1. Sejbuk M, Mirończuk-Chodakowska I, Witkowska AM. [Sleep quality: A narrative review on nutrition, stimulants, and physical activity as important factors](https:\/\/doi.org\/10.3390%2Fnu14091912). *Nutrients*. 2022;14(9):1912. doi:10.3390\/nu14091912\n2. Harvard Health Publishing. [Fight fatigue with fluids](https:\/\/www.health.harvard.edu\/healthbeat\/fight-fatigue-with-fluids).\n3. National Institutes of Health, National Institute on Aging. [Fatigue in older adults](https:\/\/www.nia.nih.gov\/health\/fatigue\/fatigue-older-adults).\n4. Hartescu I, Morgan K, Stevinson CD. [Increased physical activity improves sleep and mood outcomes in inactive people with insomnia: A randomized controlled trial](https:\/\/doi.org\/10.1111\/jsr.12297). *J Sleep Res*. 2015;24(5):526-534. doi:10.1111\/jsr.12297\n5. National Institutes of Health, U.S. National Library of Medicine: MedlinePlus. [Are you getting too much exercise?](https:\/\/medlineplus.gov\/ency\/patientinstructions\/000807.htm)\n6. American Psychological Association. [Stress and sleep](https:\/\/www.apa.org\/news\/press\/releases\/stress\/2013\/sleep).\n7. Sin NL, Wen JH, Klaiber P, Buxton OM, Almeida DM. [Sleep duration and affective reactivity to stressors and positive events in daily life](https:\/\/doi.org\/10.1037\/hea0001033). *Health Psychol*. 2020; doi:10.1037\/hea0001033\n8. University of Pennsylvania. Penn Medicine. [What Is Anemia?](https:\/\/www.pennmedicine.org\/for-patients-and-visitors\/patient-information\/conditions-treated-a-to-z\/anemia)\n9. Zielinski MR, Systrom DM, Rose NR. [Fatigue, sleep, and autoimmune and related disorders](https:\/\/doi.org\/10.3389\/fimmu.2019.01827). *Front Immunol*. 2019;10:1827. doi:10.3389\/fimmu.2019.01827\n10. American Cancer Society. [What is fatigue or weakness?](https:\/\/www.cancer.org\/cancer\/managing-cancer\/side-effects\/fatigue\/what-is-cancer-related-fatigue.html)\n11. Sotzny F, Blanco J, Capelli E, et al. [Myalgic encephalomyelitis\/chronic fatigue syndrome - Evidence for an autoimmune disease](https:\/\/doi.org\/10.1016\/j.autrev.2018.01.009). *Autoimmun Rev*. 2018;17(6):601-609. doi:10.1016\/j.autrev.2018.01.009\n12. Goërtz YMJ, Spruit MA, Van 't Hul AJ, et al. [Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation](https:\/\/doi.org\/10.1177\/1753466619878128). *Ther Adv Respir Dis*. 2019;13:1753466619878128. doi:10.1177\/1753466619878128\n13. Corfield EC, Martin NG, Nyholt DR. [Co-occurrence and symptomatology of fatigue and depression](https:\/\/doi.org\/10.1016\/j.comppsych.2016.08.004). *Compr Psychiatry*. 2016;71:1-10. doi:10.1016\/j.comppsych.2016.08.004\n14. Allen J, Romay-Tallon R, Brymer KJ, Caruncho HJ, Kalynchuk LE. [Mitochondria and mood: Mitochondrial dysfunction as a key player in the manifestation of depression](https:\/\/doi.org\/10.3389\/fnins.2018.00386). *Front Neurosci*. 2018;12:386. doi:10.3389\/fnins.2018.00386\n15. Kalra S, Sahay R. [Diabetes fatigue syndrome](https:\/\/doi.org\/10.1007\/s13300-018-0453-x). *Diabetes Ther*. 2018;9(4):1421-1429. doi:10.1007\/s13300-018-0453-x\n16. Littlejohn G, Guymer E. [Key milestones contributing to the understanding of the mechanisms underlying fibromyalgia](https:\/\/doi.org\/10.3390\/biomedicines8070223). *Biomedicines*. 2020;8(7):223. doi:10.3390\/biomedicines8070223\n17. Wostyn P. [COVID-19 and chronic fatigue syndrome: Is the worst yet to come?](https:\/\/doi.org\/10.1016\/j.mehy.2020.110469). *Med Hypotheses*. 2021;146:110469. doi:10.1016\/j.mehy.2020.110469\n18. Kerr JR. [Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors](https:\/\/doi.org\/10.1136\/jclinpath-2019-205822). *J Clin Pathol*. 2019;72(10):651-658. doi:10.1136\/jclinpath-2019-205822\n19. Pasta A, Formisano E, Calabrese F, et al. [Food intolerances, food allergies, and IBS: Lights and shadows](https:\/\/doi.org\/10.3390\/nu16020265). *Nutrients*. 2024;16(2):265. doi:10.3390\/nu16020265\n20. National Institute of Diabetes and Digestive and Kidney Diseases. [Anemia in chronic kidney disease](https:\/\/www.niddk.nih.gov\/health-information\/kidney-disease\/anemia).\n21. Taylor-Swanson L, Wong AE, Pincus D, et al. [The dynamics of stress and fatigue across menopause: Attractors, coupling, and resilience](https:\/\/doi.org\/10.1097\/gme.0000000000001025). *Menopause*. 2018;25(4):380-390. doi:10.1097\/GME.0000000000001025\n22. Bai G, Korfage IJ, Groen EH, Jaddoe VW, Mautner E, Raat H. [Associations between Nausea, Vomiting, Fatigue and Health-Related Quality of Life of Women in Early Pregnancy: The Generation R Study](https:\/\/doi.org\/10.1371%2Fjournal.pone.0166133). PLoS One. 2016 Nov 4;11(11):e0166133. doi: 10.1371\/journal.pone.0166133\n23. Harvard Medical School, Harvard Health Publishing. [The lowdown on thyroid slowdown](https:\/\/www.health.harvard.edu\/newsletter_article\/the-lowdown-on-thyroid-slowdown).\n24. American Thyroid Association. [Hyperthyroidism](https:\/\/www.thyroid.org\/hyperthyroidism\/).\n25. Harvard Medical School, Harvard Health Publishing. [5 overlooked symptoms that may signal heart trouble](https:\/\/www.health.harvard.edu\/heart-health\/5-overlooked-symptoms-that-may-signal-heart-trouble).\n26. National Institutes of Health, National Heart, Lung, and Blood Institute. [Circadian rhythm disorders](https:\/\/www.nhlbi.nih.gov\/health\/circadian-rhythm-disorders).\n27. National Institutes of Health, National Heart, Lung, and Blood Institute. [Insomnia](https:\/\/www.nhlbi.nih.gov\/health\/insomnia).\n28. de Oliveira MM, Conti C, Prado GF. [Pharmacological treatment for Kleine-Levin syndrome](https:\/\/doi.org\/10.1002\/14651858.cd006685.pub4). *Cochrane Database Syst Rev*. 2016;2016(5):CD006685. doi:10.1002\/14651858.CD006685.pub4\n29. National Organization for Rare Disorders. [Narcolepsy](https:\/\/rarediseases.org\/rare-diseases\/narcolepsy\/).\n30. National Institute of Neurological Disorders and Stroke. [Restless legs syndrome](https:\/\/www.ninds.nih.gov\/health-information\/disorders\/restless-legs-syndrome).\n31. Mount Sinai. [Restless leg syndrome and related disorders](https:\/\/www.mountsinai.org\/health-library\/report\/restless-legs-syndrome-and-related-disorders).\n32. Raheem OA, Orosco RK, Davidson TM, Lakin C. [Clinical predictors of nocturia in the sleep apnea population](https:\/\/doi.org\/10.4103\/0974-7796.127019). *Urol Ann.* 2014;6(1):31-5. doi:10.4103\/0974-7796.127019\n33. Harvard Medical School, Harvard Health Publishing. [What to do when medication makes you sleepy](https:\/\/www.health.harvard.edu\/medications\/what-to-do-when-medication-makes-you-sleepy#:~:text=Common%20culprits%20that%20cause%20sleepiness,to%20treat%20high%20blood%20pressure%2C).\n\n![Brandon Peters, M.D.](https:\/\/www.verywellhealth.com\/thmb\/BbtKTL7wVNFD-4Y2KIj4azA0HpE=\/144x144\/filters:no_upscale\\(\\):max_bytes\\(150000\\):strip_icc\\(\\)\/BrandonPetersMD_1000-5143e542c3084368b1220c4b86ede01c.png)\n\nBy [Brandon Peters, MD](https:\/\/www.verywellhealth.com\/brandon-peters-md-3014640)   \n Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine.\n\nWas this page helpful?\n\nThanks for your feedback\\!\n\nWhat is your feedback?","meta_canonical":null}

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Boilerpipe Text	Key Takeaways Fatigue can be caused by medical conditions like sleep apnea, diabetes, or thyroid disease. Poor sleep habits, such as not getting enough sleep or having an uncomfortable sleeping environment, can make you tired. Lifestyle choices, such as unhealthy diet, dehydration, and lack of exercise, can decrease your energy levels. The causes of constant tiredness and fatigue can stem from various factors that affect your energy levels throughout the day. These causes typically fall into four categories: lifestyle factors, medical conditions, sleep disorders, and mental health issues. Verywell / Cindy Chung 1:39 Click Play to Learn What You Can Do to Feel Less Tired Everyday Habits That Can Make You Tired Your daily habits can significantly affect how alert and energetic you feel throughout the day. Consider discussing the following factors with your healthcare provider: Diet: Your body gets energy from food. An unbalanced diet or skipping meals can make you feel tired. Diet-related causes of fatigue include deficiencies in zinc, vitamin B12, or vitamin D, blood sugar changes, excessive alcohol, and too much caffeine. Dehydration : Dehydration occurs when you lose more fluids than you take in. Since water makes up 50% to 60% of your body weight, sweating, urination, heat, or illness can quickly deplete your hydration levels. While drinking eight 8-ounce glasses of water daily is a common guideline, very pale yellow or clear urine generally indicates proper hydration. Poor sleep habits: Daytime fatigue may result from not getting enough quality sleep. Poor habits like sleeping in a noisy or uncomfortable environment, skipping a bedtime routine, exercising too close to bedtime, or napping late in the day can disrupt your rest. Additionally, not meeting the sleep needs for your age (eight to nine hours a night for adults ages 18 to 60) can leave you feeling tired. Inactive lifestyle : Sitting for long periods can lead to restless and poor-quality sleep. Engaging in regular physical activity can improve your sleep and mental well-being. One study found that participants who exercised for 150 minutes a week experienced less insomnia, depression, and anxiety compared to those who were less active.. Overexertion: Overexerting yourself through excessive exercise or other activities can leave your body too depleted to recover. This can lead to fatigue, poor sleep, and low motivation. Symptoms of overexertion may include mood swings, sore limbs, frequent illness, and a decline in performance at work or home. Stress : Stress can disrupt your sleep, and poor sleep can increase stress and fatigue. A survey found 43% of adults lost sleep due to stress, and 37% reported feeling tired because of it. Getting quality sleep helps maintain a positive mood during stressful times and increases joy from good experiences. Could a Health Condition Be Draining Your Energy? Feeling fatigued, weak, or sleepy can be symptoms of various medical conditions that impact your energy. Daytime sleepiness may be linked to these underlying causes: Anemia : Anemia is a condition in which your body has fewer red blood cells or they don't function properly, reducing the blood's ability to deliver oxygen to your organs. This can cause symptoms like fatigue, headaches, difficulty concentrating, irritability, and numbness in the hands and feet. The most common type is iron-deficiency anemia, but other causes include inherited disorders, chronic illnesses, and pregnancy. Autoimmune disease: Autoimmune diseases occur when your immune system mistakenly attacks your own body, causing tissue damage and chronic inflammation. Conditions like rheumatoid arthritis, lupus, multiple sclerosis, and inflammatory bowel disease can lead to fatigue and disrupt your metabolism, nervous system, and sleep patterns. They may also cause imbalances in cytokines, proteins that regulate inflammation, mood, and sleep. Cancer: More than 80% of people with cancer experience cancer-related fatigue , which often doesn't improve with rest and can be an early sign of the disease. Fatigue can result from low blood counts, disturbed electrolytes, altered hormone or cytokine levels, and changes in cell function caused by cancer. Treatments like chemotherapy, immunotherapy, and radiation can also contribute to fatigue. Chronic fatigue syndrome : Chronic fatigue syndrome (ME/CFS) causes extreme fatigue that worsens with minimal exertion, doesn't improve with rest, and often includes flu-like symptoms and cognitive issues like "brain fog." The exact cause is unknown, but it may be linked to infections, chronic stress, autoimmune responses, or cytokine-related inflammation. Chronic obstructive pulmonary disease (COPD): This chronic disease causes wheezing, shortness of breath, and extra mucus, making it hard to breathe. Fatigue is common in COPD, but it may not always be directly linked to breathing difficulties. The disease progresses over time, and it is especially common in current or former smokers. Depression: This mood disorder causes sadness, loss of interest, and physical symptoms like fatigue. Daytime sleepiness may result from insomnia or other sleep problems often linked to depression, and fatigue may serve as an early warning sign. Biochemical similarities between depression and ME/CFS might explain fatigue as a shared symptom. Diabetes : Diabetes fatigue syndrome refers to persistent fatigue experienced by people with diabetes. Possible causes include low blood sugar, hormonal imbalances, treatment side effects, overlapping conditions, and lifestyle factors like diet. Fibromyalgia : Fibromyalgia is a chronic pain condition. It's caused by dysfunction in the central nervous system, which heightens sensitivity and turns harmless sensations into pain (allodynia). Fatigue is also a key symptom of fibromyalgia. This fatigue may be due to biochemical changes, inflammation, sleep disorders, and sleep disruptions. Heart disease: If you have fatigue that's new and constant, it may be an early warning sign of heart failure or, less often, coronary artery disease . These conditions limit the amount of oxygen-rich blood that gets to your muscles or to the heart itself. Your heart and brain need oxygen. When you have heart disease, your body limits the blood sent to less important parts like the limbs, leading to reduced energy and fatigue. Infections: Fatigue is common during and after infectious illnesses like COVID-19, influenza, mononucleosis, and Lyme disease . While tiredness often resolves as the illness clears, some people experience lingering fatigue, known as post-viral fatigue or, in the case of COVID-19, long COVID . Researchers are exploring links between these persistent symptoms and conditions like ME/CFS, especially for viruses like Epstein-Barr, which can reactivate and contribute to fatigue and autoimmune diseases. Food allergies and intolerances : Food allergies and intolerances can cause fatigue by triggering immune responses or gastrointestinal distress that depletes energy levels. Reactions to allergens, such as dairy, gluten, or nuts, may lead to inflammation, poor nutrient absorption, or disrupted sleep. Chronic exposure to problematic foods can worsen fatigue over time, especially if the underlying issue goes unaddressed. Kidney disease : Kidney disease can cause fatigue due to the buildup of toxins in the blood when the kidneys are not functioning properly. This can lead to anemia, as the kidneys produce less erythropoietin, a hormone essential for red blood cell production. Electrolyte imbalances and reduced nutrient absorption may also contribute to low energy levels. Menopause : The transition to menopause, including perimenopause and the early post-menopausal stage, often brings fatigue along with symptoms like hot flashes, night sweats, and mood swings. Fatigue may stem from sleep disruptions, hormonal changes, aging, or stress. Pregnancy : Pregnancy places extra demands on the body, often causing fatigue, especially during the first and third trimesters. Factors contributing to this tiredness include the energy required to support the baby, hormonal changes, low blood sugar or pressure, and disrupted sleep. Stress and digestive changes can also play a role in pregnancy-related exhaustion. Thyroid disease : Thyroid hormone imbalances, whether high (hyperthyroidism) or low (hypothyroidism), can cause fatigue due to their effects on metabolism. Hyperthyroidism speeds up bodily processes, leading to symptoms like anxiety, sleep disruption, and eventual exhaustion as energy reserves deplete, while hypothyroidism slows everything down, causing fatigue alongside weight gain, depression, and memory problems. Recognizing a Heart Attack A heart attack requires immediate medical attention. Call 9-1-1 if you or someone else suddenly experiences: Chest pain or pressure, which can also be in the upper abdomen Pain that spreads to the jaw, neck, back, arms, or stomach Shortness of breath Dizziness or fainting Nausea or vomiting Extreme fatigue How Sleep Disorders Affect Your Energy Levels Various circadian rhythm disorders can leave you feeling too sleepy during the day . The circadian rhythm is your body's natural clock. It helps to coordinate your activities based on when it's light and dark in your environment. If your internal timing is misaligned, you may find yourself with excessive daytime sleepiness. Six common circadian rhythm disorders include: Advanced sleep phase syndrome: The distinguishing feature is falling asleep and waking up earlier than you want, usually by about three hours. Delayed sleep phase syndrome: This causes difficulty falling asleep and makes it extremely hard to wake up. Irregular sleep-wake rhythm: This occurs when the circadian rhythm becomes completely disconnected from the natural day-night cycle. Sleep is fragmented, with short spells scattered throughout the day. Jet lag: A temporary rhythm disorder associated with travel across several time zones. To adjust, it may take one day for every time zone you cross. Non-entrained (non-24) disorder: This usually occurs in visually impaired people. The sleep cycle is typically a little longer than average and thus becomes more out of sync every day. Shift-work sleep disorder: Poor sleep is caused by working at night and sleeping during the day. This can lead to increased accidents and possibly a higher risk of some forms of cancer. Other sleep disorders that can result in constant tiredness or fatigue include: Insomnia : Insomnia, which makes it hard to fall or stay asleep, can be occasional or a chronic issue that causes constant fatigue. It may result from factors like genetics, irregular sleep schedules, stimulants, alcohol, drug use, or high stress levels. Environmental factors, sedentary lifestyles, and excessive light exposure, especially from screens before bed, can also contribute. Kleine-Levin syndrome: Kleine-Levin syndrome, a rare condition primarily affecting young men, causes recurrent episodes of excessive sleepiness that can last days to months and be severely debilitating. These episodes often disrupt daily life and school, with symptoms including hallucinations, hypersexual or compulsive behaviors, binge eating, and mood or cognitive disturbances. Narcolepsy : Narcolepsy disrupts the body's ability to regulate sleep, causing sudden sleep attacks during the day and wakefulness elements during sleep. Key symptoms include cataplexy, a sudden loss of muscle control triggered by emotions, and vivid hallucinations during sleep transitions. Sleep paralysis, frequent nighttime awakenings, and performing actions during sleep attacks without memory of them are also common. Restless leg syndrome (RLS): Disorders causing excessive movements during sleep, like RLS, can disrupt sleep and lead to daytime fatigue. RLS creates an uncomfortable sensation in the legs and an urge to move, typically worsening in the evening or when lying down. Movement temporarily relieves the discomfort but can interfere with restful sleep. Periodic limb movement syndrome (PLMS): This condition related to RLS involves sudden jerking movements that occur during sleep. These may be repetitive, disturbing your sleep and potentially that of your bed partner. Sleep apnea : Sleep apnea causes repeated pauses in breathing during sleep, often followed by loud snorts or gasps that disrupt sleep cycles. These interruptions shift you into lighter sleep stages, leaving you tired even if you don't recall waking. Symptoms include snoring, morning dry mouth or headaches, teeth grinding, sexual dysfunction, and frequent nighttime urination. Warning: Risk of Fatal Complications Sleep apnea puts a strain on your heart. It can lead to high blood pressure, cardiomyopathy (enlarged muscle tissue in the heart), heart failure, heart attack, and stroke. This makes proper diagnosis and treatment of sleep apnea especially important. Medications That Cause Drowsiness Drowsiness and fatigue are common side effects of medications. If you have daytime tiredness, your healthcare provider will likely look into what medications you're taking. Drugs that can make you tired include: Analgesics: Painkillers including opioids such as Vicodin (hydrocodone-acetaminophen), OxyContin (oxycodone) Antiseizure medications (ASMs): Seizure prevention drugs such as Neurontin (gabapentin) and Lyrica (pregabalin) Antidepressants: Tricyclics and SSRIs/SNRIs including amitriptyline, Prozac (fluoxetine), Cymbalta (duloxetine) Antiemetics: Drugs for nausea, vomiting, and motion sickness such as Dramamine (dimenhydrinate), Zyprexa (olanzapine), Reglan (metoclopramide) Antihistamines: Allergy medications including Zyrtec (cetirizine), Claritin (loratadine), Benadryl (diphenhydramine) Antipsychotics: Drugs for schizophrenia, psychosis in bipolar disorder, depression, and Alzheimer's diseas e including Abilify (aripiprazole) , Risperdal (risperidone), Seroquel (quetiapine) Benzodiazepines: Tranquilizers and sedatives such as Librium (chlordiazepoxide), Valium (diazepam) Blood pressure drugs: Diuretics, ARBs, calcium channel blockers, beta-blockers including Lasix (furosemide), Avapro (irbesartan), verapamil HCL, Toprol-XL (metoprolol succinate) Muscle relaxants: Including Soma (carisoprodol), Lorzone (chlorzoxazone), Amrix (cyclobenzaprine) Sedatives: Non-benzodiazepine sedative/hypnotics such as Ambien (zolpidem), Sonata (zaleplon), Lunesta (eszopiclone) Statins: Especially fat-soluble drugs including Lipitor (atorvastatin), lovastatin, Vytorin (ezetimibe/simvastatin), Zocor (simvastatin) Steroids: Used for inflammation, allergies, skin diseases, certain cancers, and after organ transplants. Some may cause insomnia, including prednisolone, methylprednisolone, and dexamethasone. 33 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Sejbuk M, Mirończuk-Chodakowska I, Witkowska AM. Sleep quality: A narrative review on nutrition, stimulants, and physical activity as important factors . Nutrients . 2022;14(9):1912. doi:10.3390/nu14091912 Harvard Health Publishing. Fight fatigue with fluids . National Institutes of Health, National Institute on Aging. Fatigue in older adults . Hartescu I, Morgan K, Stevinson CD. Increased physical activity improves sleep and mood outcomes in inactive people with insomnia: A randomized controlled trial . J Sleep Res . 2015;24(5):526-534. doi:10.1111/jsr.12297 National Institutes of Health, U.S. National Library of Medicine: MedlinePlus. Are you getting too much exercise? American Psychological Association. Stress and sleep . Sin NL, Wen JH, Klaiber P, Buxton OM, Almeida DM. Sleep duration and affective reactivity to stressors and positive events in daily life . Health Psychol . 2020; doi:10.1037/hea0001033 University of Pennsylvania. Penn Medicine. What Is Anemia? Zielinski MR, Systrom DM, Rose NR. Fatigue, sleep, and autoimmune and related disorders . Front Immunol . 2019;10:1827. doi:10.3389/fimmu.2019.01827 American Cancer Society. What is fatigue or weakness? Sotzny F, Blanco J, Capelli E, et al. Myalgic encephalomyelitis/chronic fatigue syndrome - Evidence for an autoimmune disease . Autoimmun Rev . 2018;17(6):601-609. doi:10.1016/j.autrev.2018.01.009 Goërtz YMJ, Spruit MA, Van 't Hul AJ, et al. Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation . Ther Adv Respir Dis . 2019;13:1753466619878128. doi:10.1177/1753466619878128 Corfield EC, Martin NG, Nyholt DR. Co-occurrence and symptomatology of fatigue and depression . Compr Psychiatry . 2016;71:1-10. doi:10.1016/j.comppsych.2016.08.004 Allen J, Romay-Tallon R, Brymer KJ, Caruncho HJ, Kalynchuk LE. Mitochondria and mood: Mitochondrial dysfunction as a key player in the manifestation of depression . Front Neurosci . 2018;12:386. doi:10.3389/fnins.2018.00386 Kalra S, Sahay R. Diabetes fatigue syndrome . Diabetes Ther . 2018;9(4):1421-1429. doi:10.1007/s13300-018-0453-x Littlejohn G, Guymer E. Key milestones contributing to the understanding of the mechanisms underlying fibromyalgia . Biomedicines . 2020;8(7):223. doi:10.3390/biomedicines8070223 Wostyn P. COVID-19 and chronic fatigue syndrome: Is the worst yet to come? . Med Hypotheses . 2021;146:110469. doi:10.1016/j.mehy.2020.110469 Kerr JR. Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors . J Clin Pathol . 2019;72(10):651-658. doi:10.1136/jclinpath-2019-205822 Pasta A, Formisano E, Calabrese F, et al. Food intolerances, food allergies, and IBS: Lights and shadows . Nutrients . 2024;16(2):265. doi:10.3390/nu16020265 National Institute of Diabetes and Digestive and Kidney Diseases. Anemia in chronic kidney disease . Taylor-Swanson L, Wong AE, Pincus D, et al. The dynamics of stress and fatigue across menopause: Attractors, coupling, and resilience . Menopause . 2018;25(4):380-390. doi:10.1097/GME.0000000000001025 Bai G, Korfage IJ, Groen EH, Jaddoe VW, Mautner E, Raat H. Associations between Nausea, Vomiting, Fatigue and Health-Related Quality of Life of Women in Early Pregnancy: The Generation R Study . PLoS One. 2016 Nov 4;11(11):e0166133. doi: 10.1371/journal.pone.0166133 Harvard Medical School, Harvard Health Publishing. The lowdown on thyroid slowdown . American Thyroid Association. Hyperthyroidism . Harvard Medical School, Harvard Health Publishing. 5 overlooked symptoms that may signal heart trouble . National Institutes of Health, National Heart, Lung, and Blood Institute. Circadian rhythm disorders . National Institutes of Health, National Heart, Lung, and Blood Institute. Insomnia . de Oliveira MM, Conti C, Prado GF. Pharmacological treatment for Kleine-Levin syndrome . Cochrane Database Syst Rev . 2016;2016(5):CD006685. doi:10.1002/14651858.CD006685.pub4 National Organization for Rare Disorders. Narcolepsy . National Institute of Neurological Disorders and Stroke. Restless legs syndrome . Mount Sinai. Restless leg syndrome and related disorders . Raheem OA, Orosco RK, Davidson TM, Lakin C. Clinical predictors of nocturia in the sleep apnea population . Urol Ann. 2014;6(1):31-5. doi:10.4103/0974-7796.127019 Harvard Medical School, Harvard Health Publishing. What to do when medication makes you sleepy . By Brandon Peters, MD Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine. Was this page helpful? Thanks for your feedback! What is your feedback?
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Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Ⓒ 2026 People Inc. — All rights reserved # Why Am I Always Tired? By [Brandon Peters, MD](https://www.verywellhealth.com/brandon-peters-md-3014640) Updated on March 12, 2026 Medically reviewed by [Sanja Jelic, MD](https://www.verywellhealth.com/sanja-jelic-md-4685032) Table of Contents View All Table of Contents - [Lifestyle Factors](https://www.verywellhealth.com/reasons-why-you-feel-sleepy-3014818#toc-everyday-habits-that-can-make-you-tired) - [Medical Causes](https://www.verywellhealth.com/reasons-why-you-feel-sleepy-3014818#toc-could-a-health-condition-be-draining-your-energy) - [Sleep Disorders](https://www.verywellhealth.com/reasons-why-you-feel-sleepy-3014818#toc-how-sleep-disorders-affect-your-energy-levels) - [Medications](https://www.verywellhealth.com/reasons-why-you-feel-sleepy-3014818#toc-medications-that-cause-drowsiness) ### Key Takeaways - Fatigue can be caused by medical conditions like sleep apnea, diabetes, or thyroid disease. - Poor sleep habits, such as not getting enough sleep or having an uncomfortable sleeping environment, can make you tired. - Lifestyle choices, such as unhealthy diet, dehydration, and lack of exercise, can decrease your energy levels. The causes of constant tiredness and fatigue can stem from various factors that affect your energy levels throughout the day. These causes typically fall into four categories: lifestyle factors, medical conditions, sleep disorders, and mental health issues. Verywell / Cindy Chung 1:39 ### Click Play to Learn What You Can Do to Feel Less Tired This video has been medically reviewed by [Chris Vincent, MD](https://www.verywellhealth.com/chris-vincent-md-4774437). ## Everyday Habits That Can Make You Tired Your daily habits can significantly affect how alert and energetic you feel throughout the day. Consider discussing the following factors with your healthcare provider: - Diet: Your body gets energy from food. An unbalanced diet or skipping meals can make you feel tired. Diet-related causes of fatigue include deficiencies in zinc, vitamin B12, or vitamin D, blood sugar changes, excessive alcohol, and too much caffeine. - [Dehydration](https://www.verywellhealth.com/diseases-that-cause-dehydration-in-adults-8679450): Dehydration occurs when you lose more fluids than you take in. Since water makes up 50% to 60% of your body weight, sweating, urination, heat, or illness can quickly deplete your hydration levels. While drinking eight 8-ounce glasses of water daily is a common guideline, very pale yellow or clear urine generally indicates proper hydration. - Poor sleep habits: Daytime fatigue may result from not getting enough quality sleep. Poor habits like sleeping in a noisy or uncomfortable environment, skipping a bedtime routine, exercising too close to bedtime, or napping late in the day can disrupt your rest. Additionally, not meeting the sleep needs for your age (eight to nine hours a night for adults ages 18 to 60) can leave you feeling tired. - [Inactive lifestyle](https://www.verywellhealth.com/sitting-down-8629219): Sitting for long periods can lead to restless and poor-quality sleep. Engaging in regular physical activity can improve your sleep and mental well-being. One study found that participants who exercised for 150 minutes a week experienced less insomnia, depression, and anxiety compared to those who were less active.. - Overexertion: Overexerting yourself through excessive exercise or other activities can leave your body too depleted to recover. This can lead to fatigue, poor sleep, and low motivation. Symptoms of overexertion may include mood swings, sore limbs, frequent illness, and a decline in performance at work or home. - [Stress](https://www.verywellhealth.com/psychological-stress-5205714): Stress can disrupt your sleep, and poor sleep can increase stress and fatigue. A survey found 43% of adults lost sleep due to stress, and 37% reported feeling tired because of it. Getting quality sleep helps maintain a positive mood during stressful times and increases joy from good experiences. ## Could a Health Condition Be Draining Your Energy? Feeling fatigued, weak, or sleepy can be symptoms of various medical conditions that impact your energy. Daytime sleepiness may be linked to these underlying causes: - [Anemia](https://www.verywellhealth.com/anemia-symptoms-4628300): Anemia is a condition in which your body has fewer red blood cells or they don't function properly, reducing the blood's ability to deliver oxygen to your organs. This can cause symptoms like fatigue, headaches, difficulty concentrating, irritability, and numbness in the hands and feet. The most common type is iron-deficiency anemia, but other causes include inherited disorders, chronic illnesses, and pregnancy. - Autoimmune disease: Autoimmune diseases occur when your immune system mistakenly attacks your own body, causing tissue damage and chronic inflammation. Conditions like rheumatoid arthritis, lupus, multiple sclerosis, and [inflammatory bowel disease](https://www.verywellhealth.com/ibd-crohns-colitis-overview-4581950) can lead to fatigue and disrupt your metabolism, nervous system, and sleep patterns. They may also cause imbalances in cytokines, proteins that regulate inflammation, mood, and sleep. - Cancer: More than 80% of people with cancer experience [cancer-related fatigue](https://www.verywellhealth.com/is-fatigue-a-symptom-of-cancer-514435), which often doesn't improve with rest and can be an early sign of the disease. Fatigue can result from low blood counts, disturbed electrolytes, altered hormone or cytokine levels, and changes in cell function caused by cancer. Treatments like chemotherapy, immunotherapy, and radiation can also contribute to fatigue. - [Chronic fatigue syndrome](https://www.verywellhealth.com/understanding-chronic-fatigue-syndrome-4158459): Chronic fatigue syndrome (ME/CFS) causes extreme fatigue that worsens with minimal exertion, doesn't improve with rest, and often includes flu-like symptoms and cognitive issues like "brain fog." The exact cause is unknown, but it may be linked to infections, chronic stress, autoimmune responses, or cytokine-related inflammation. - [Chronic obstructive pulmonary disease](https://www.verywellhealth.com/copd-4014741) (COPD): This chronic disease causes wheezing, shortness of breath, and extra mucus, making it hard to breathe. Fatigue is common in COPD, but it may not always be directly linked to breathing difficulties. The disease progresses over time, and it is especially common in current or former smokers. - Depression: This mood disorder causes sadness, loss of interest, and physical symptoms like fatigue. Daytime sleepiness may result from insomnia or other sleep problems often linked to depression, and fatigue may serve as an early warning sign. Biochemical similarities between depression and ME/CFS might explain fatigue as a shared symptom. - [Diabetes](https://www.verywellhealth.com/undiagnosed-diabetes-5179188): Diabetes fatigue syndrome refers to persistent fatigue experienced by people with diabetes. Possible causes include low blood sugar, hormonal imbalances, treatment side effects, overlapping conditions, and lifestyle factors like diet. - [Fibromyalgia](https://www.verywellhealth.com/fibromyalgia-7369351): Fibromyalgia is a chronic pain condition. It's caused by dysfunction in the central nervous system, which heightens sensitivity and turns harmless sensations into pain (allodynia). Fatigue is also a key symptom of fibromyalgia. This fatigue may be due to biochemical changes, inflammation, sleep disorders, and sleep disruptions. - Heart disease: If you have fatigue that's new and constant, it may be an early warning sign of heart failure or, less often, [coronary artery disease](https://www.verywellhealth.com/heart-disease-7481236). These conditions limit the amount of oxygen-rich blood that gets to your muscles or to the heart itself. Your heart and brain need oxygen. When you have heart disease, your body limits the blood sent to less important parts like the limbs, leading to reduced energy and fatigue. - Infections: Fatigue is common during and after infectious illnesses like COVID-19, influenza, mononucleosis, and [Lyme disease](https://www.verywellhealth.com/lyme-disease-7151644). While tiredness often resolves as the illness clears, some people experience lingering fatigue, known as post-viral fatigue or, [in the case of COVID-19, long COVID](https://www.verywellhealth.com/nicotine-patches-long-covid-treatment-8705089). Researchers are exploring links between these persistent symptoms and conditions like ME/CFS, especially for viruses like Epstein-Barr, which can reactivate and contribute to fatigue and autoimmune diseases. - [Food allergies and intolerances](https://www.verywellhealth.com/most-common-food-sensitivities-1944845): Food allergies and intolerances can cause fatigue by triggering immune responses or gastrointestinal distress that depletes energy levels. Reactions to allergens, such as dairy, gluten, or nuts, may lead to inflammation, poor nutrient absorption, or disrupted sleep. Chronic exposure to problematic foods can worsen fatigue over time, especially if the underlying issue goes unaddressed. - [Kidney disease](https://www.verywellhealth.com/acute-vs-chronic-kidney-disease-5221287): Kidney disease can cause fatigue due to the buildup of toxins in the blood when the kidneys are not functioning properly. This can lead to anemia, as the kidneys produce less erythropoietin, a hormone essential for red blood cell production. Electrolyte imbalances and reduced nutrient absorption may also contribute to low energy levels. - [Menopause](https://www.verywellhealth.com/side-effects-of-menopause-5217701): The transition to menopause, including perimenopause and the early post-menopausal stage, often brings fatigue along with symptoms like hot flashes, night sweats, and mood swings. Fatigue may stem from sleep disruptions, hormonal changes, aging, or stress. - [Pregnancy](https://www.verywellhealth.com/pregnancy-facts-and-statistics-5324188): Pregnancy places extra demands on the body, often causing fatigue, especially during the first and third trimesters. Factors contributing to this tiredness include the energy required to support the baby, hormonal changes, low blood sugar or pressure, and disrupted sleep. Stress and digestive changes can also play a role in pregnancy-related exhaustion. - [Thyroid disease](https://www.verywellhealth.com/hypothyroidism-hyperthyroidism-5180646): Thyroid hormone imbalances, whether high (hyperthyroidism) or low (hypothyroidism), can cause fatigue due to their effects on metabolism. Hyperthyroidism speeds up bodily processes, leading to symptoms like anxiety, sleep disruption, and eventual exhaustion as energy reserves deplete, while hypothyroidism slows everything down, causing fatigue alongside weight gain, depression, and memory problems. ### Recognizing a Heart Attack A heart attack requires immediate medical attention. Call 9-1-1 if you or someone else suddenly experiences: - Chest pain or pressure, which can also be in the upper abdomen - Pain that spreads to the jaw, neck, back, arms, or stomach - Shortness of breath - Dizziness or fainting - Nausea or vomiting - Extreme fatigue ## How Sleep Disorders Affect Your Energy Levels Various circadian rhythm disorders can leave you [feeling too sleepy during the day](https://www.verywellhealth.com/why-am-i-sleepy-after-eating-lunch-3014827). The circadian rhythm is your body's natural clock. It helps to coordinate your activities based on when it's light and dark in your environment. If your internal timing is misaligned, you may find yourself with excessive daytime sleepiness. Six common circadian rhythm disorders include: - Advanced sleep phase syndrome: The distinguishing feature is falling asleep and waking up earlier than you want, usually by about three hours. - Delayed sleep phase syndrome: This causes difficulty falling asleep and makes it extremely hard to wake up. - Irregular sleep-wake rhythm: This occurs when the circadian rhythm becomes completely disconnected from the natural day-night cycle. Sleep is fragmented, with short spells scattered throughout the day. - Jet lag: A temporary rhythm disorder associated with travel across several time zones. To adjust, it may take one day for every time zone you cross. - Non-entrained (non-24) disorder: This usually occurs in visually impaired people. The sleep cycle is typically a little longer than average and thus becomes more out of sync every day. - Shift-work sleep disorder: Poor sleep is caused by working at night and sleeping during the day. This can lead to increased accidents and possibly a higher risk of some forms of cancer. Other sleep disorders that can result in constant tiredness or fatigue include: - [Insomnia](https://www.verywellhealth.com/what-is-insomnia-the-features-symptoms-and-causes-3014805): Insomnia, which makes it hard to fall or stay asleep, can be occasional or a chronic issue that causes constant fatigue. It may result from factors like genetics, irregular sleep schedules, stimulants, alcohol, drug use, or high stress levels. Environmental factors, sedentary lifestyles, and excessive light exposure, especially from screens before bed, can also contribute. - Kleine-Levin syndrome: Kleine-Levin syndrome, a rare condition primarily affecting young men, causes recurrent episodes of excessive sleepiness that can last days to months and be severely debilitating. These episodes often disrupt daily life and school, with symptoms including hallucinations, hypersexual or compulsive behaviors, binge eating, and mood or cognitive disturbances. - [Narcolepsy](https://www.verywellhealth.com/restless-sleep-symptoms-causes-and-treatment-5649715): Narcolepsy disrupts the body's ability to regulate sleep, causing sudden sleep attacks during the day and wakefulness elements during sleep. Key symptoms include cataplexy, a sudden loss of muscle control triggered by emotions, and vivid hallucinations during sleep transitions. Sleep paralysis, frequent nighttime awakenings, and performing actions during sleep attacks without memory of them are also common. - [Restless leg syndrome](https://www.verywellhealth.com/restless-leg-syndrome-1746081) (RLS): Disorders causing excessive movements during sleep, like RLS, can disrupt sleep and lead to daytime fatigue. RLS creates an uncomfortable sensation in the legs and an urge to move, typically worsening in the evening or when lying down. Movement temporarily relieves the discomfort but can interfere with restful sleep. - [Periodic limb movement syndrome](https://www.verywellhealth.com/types-of-sleep-disorders-8778367) (PLMS): This condition related to RLS involves sudden jerking movements that occur during sleep. These may be repetitive, disturbing your sleep and potentially that of your bed partner. - [Sleep apnea](https://www.verywellhealth.com/effects-of-sleep-apnea-5215939): Sleep apnea causes repeated pauses in breathing during sleep, often followed by loud snorts or gasps that disrupt sleep cycles. These interruptions shift you into lighter sleep stages, leaving you tired even if you don't recall waking. Symptoms include snoring, morning dry mouth or headaches, teeth grinding, sexual dysfunction, and frequent nighttime urination. ### Warning: Risk of Fatal Complications Sleep apnea puts a strain on your heart. It can lead to high blood pressure, cardiomyopathy (enlarged muscle tissue in the heart), heart failure, heart attack, and stroke. This makes proper diagnosis and treatment of sleep apnea especially important. ## Medications That Cause Drowsiness Drowsiness and fatigue are common side effects of medications. If you have daytime tiredness, your healthcare provider will likely look into what medications you're taking. Drugs that can make you tired include: - Analgesics: Painkillers including opioids such as Vicodin (hydrocodone-acetaminophen), OxyContin (oxycodone) - Antiseizure medications (ASMs): Seizure prevention drugs such as Neurontin (gabapentin) and Lyrica (pregabalin) - Antidepressants: Tricyclics and SSRIs/SNRIs including amitriptyline, Prozac (fluoxetine), Cymbalta (duloxetine) - Antiemetics: Drugs for nausea, vomiting, and motion sickness such as Dramamine (dimenhydrinate), Zyprexa (olanzapine), Reglan (metoclopramide) - Antihistamines: Allergy medications including Zyrtec (cetirizine), Claritin (loratadine), Benadryl (diphenhydramine) - Antipsychotics: Drugs for schizophrenia, psychosis in bipolar disorder, depression, and [Alzheimer's diseas](https://www.verywellhealth.com/alzheimers-disease-7111202)e including [Abilify (aripiprazole)](https://www.verywellhealth.com/how-long-does-it-take-for-abilify-to-work-8553110), Risperdal (risperidone), Seroquel (quetiapine) - Benzodiazepines: Tranquilizers and sedatives such as Librium (chlordiazepoxide), Valium (diazepam) - Blood pressure drugs: Diuretics, ARBs, calcium channel blockers, beta-blockers including Lasix (furosemide), Avapro (irbesartan), verapamil HCL, Toprol-XL (metoprolol succinate) - Muscle relaxants: Including Soma (carisoprodol), Lorzone (chlorzoxazone), Amrix (cyclobenzaprine) - Sedatives: Non-benzodiazepine sedative/hypnotics such as Ambien (zolpidem), Sonata (zaleplon), Lunesta (eszopiclone) - Statins: Especially fat-soluble drugs including Lipitor (atorvastatin), lovastatin, Vytorin (ezetimibe/simvastatin), Zocor (simvastatin) - Steroids: Used for inflammation, allergies, skin diseases, certain cancers, and after organ transplants. Some may cause insomnia, including prednisolone, methylprednisolone, and dexamethasone. Read more: - [Health A-Z](https://www.verywellhealth.com/health-a-z-4014770) - [Sleep Disorders](https://www.verywellhealth.com/sleep-disorders-4014648) - [Insomnia & More Disorders](https://www.verywellhealth.com/insomnia-and-more-sleep-disorders-4013520) 33 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our [editorial process](https://www.verywellhealth.com/verywell-editorial-process-4777042) to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. 1. Sejbuk M, Mirończuk-Chodakowska I, Witkowska AM. [Sleep quality: A narrative review on nutrition, stimulants, and physical activity as important factors](https://doi.org/10.3390%2Fnu14091912). Nutrients. 2022;14(9):1912. doi:10.3390/nu14091912 2. Harvard Health Publishing. [Fight fatigue with fluids](https://www.health.harvard.edu/healthbeat/fight-fatigue-with-fluids). 3. National Institutes of Health, National Institute on Aging. [Fatigue in older adults](https://www.nia.nih.gov/health/fatigue/fatigue-older-adults). 4. Hartescu I, Morgan K, Stevinson CD. [Increased physical activity improves sleep and mood outcomes in inactive people with insomnia: A randomized controlled trial](https://doi.org/10.1111/jsr.12297). J Sleep Res. 2015;24(5):526-534. doi:10.1111/jsr.12297 5. National Institutes of Health, U.S. National Library of Medicine: MedlinePlus. [Are you getting too much exercise?](https://medlineplus.gov/ency/patientinstructions/000807.htm) 6. American Psychological Association. [Stress and sleep](https://www.apa.org/news/press/releases/stress/2013/sleep). 7. Sin NL, Wen JH, Klaiber P, Buxton OM, Almeida DM. [Sleep duration and affective reactivity to stressors and positive events in daily life](https://doi.org/10.1037/hea0001033). Health Psychol. 2020; doi:10.1037/hea0001033 8. University of Pennsylvania. Penn Medicine. [What Is Anemia?](https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/anemia) 9. Zielinski MR, Systrom DM, Rose NR. [Fatigue, sleep, and autoimmune and related disorders](https://doi.org/10.3389/fimmu.2019.01827). Front Immunol. 2019;10:1827. doi:10.3389/fimmu.2019.01827 10. American Cancer Society. [What is fatigue or weakness?](https://www.cancer.org/cancer/managing-cancer/side-effects/fatigue/what-is-cancer-related-fatigue.html) 11. Sotzny F, Blanco J, Capelli E, et al. [Myalgic encephalomyelitis/chronic fatigue syndrome - Evidence for an autoimmune disease](https://doi.org/10.1016/j.autrev.2018.01.009). Autoimmun Rev. 2018;17(6):601-609. doi:10.1016/j.autrev.2018.01.009 12. Goërtz YMJ, Spruit MA, Van 't Hul AJ, et al. [Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation](https://doi.org/10.1177/1753466619878128). Ther Adv Respir Dis. 2019;13:1753466619878128. doi:10.1177/1753466619878128 13. Corfield EC, Martin NG, Nyholt DR. [Co-occurrence and symptomatology of fatigue and depression](https://doi.org/10.1016/j.comppsych.2016.08.004). Compr Psychiatry. 2016;71:1-10. doi:10.1016/j.comppsych.2016.08.004 14. Allen J, Romay-Tallon R, Brymer KJ, Caruncho HJ, Kalynchuk LE. [Mitochondria and mood: Mitochondrial dysfunction as a key player in the manifestation of depression](https://doi.org/10.3389/fnins.2018.00386). Front Neurosci. 2018;12:386. doi:10.3389/fnins.2018.00386 15. Kalra S, Sahay R. [Diabetes fatigue syndrome](https://doi.org/10.1007/s13300-018-0453-x). Diabetes Ther. 2018;9(4):1421-1429. doi:10.1007/s13300-018-0453-x 16. Littlejohn G, Guymer E. [Key milestones contributing to the understanding of the mechanisms underlying fibromyalgia](https://doi.org/10.3390/biomedicines8070223). Biomedicines. 2020;8(7):223. doi:10.3390/biomedicines8070223 17. Wostyn P. [COVID-19 and chronic fatigue syndrome: Is the worst yet to come?](https://doi.org/10.1016/j.mehy.2020.110469). Med Hypotheses. 2021;146:110469. doi:10.1016/j.mehy.2020.110469 18. Kerr JR. [Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors](https://doi.org/10.1136/jclinpath-2019-205822). J Clin Pathol. 2019;72(10):651-658. doi:10.1136/jclinpath-2019-205822 19. Pasta A, Formisano E, Calabrese F, et al. [Food intolerances, food allergies, and IBS: Lights and shadows](https://doi.org/10.3390/nu16020265). Nutrients. 2024;16(2):265. doi:10.3390/nu16020265 20. National Institute of Diabetes and Digestive and Kidney Diseases. [Anemia in chronic kidney disease](https://www.niddk.nih.gov/health-information/kidney-disease/anemia). 21. Taylor-Swanson L, Wong AE, Pincus D, et al. [The dynamics of stress and fatigue across menopause: Attractors, coupling, and resilience](https://doi.org/10.1097/gme.0000000000001025). Menopause. 2018;25(4):380-390. doi:10.1097/GME.0000000000001025 22. Bai G, Korfage IJ, Groen EH, Jaddoe VW, Mautner E, Raat H. [Associations between Nausea, Vomiting, Fatigue and Health-Related Quality of Life of Women in Early Pregnancy: The Generation R Study](https://doi.org/10.1371%2Fjournal.pone.0166133). PLoS One. 2016 Nov 4;11(11):e0166133. doi: 10.1371/journal.pone.0166133 23. Harvard Medical School, Harvard Health Publishing. [The lowdown on thyroid slowdown](https://www.health.harvard.edu/newsletter_article/the-lowdown-on-thyroid-slowdown). 24. American Thyroid Association. [Hyperthyroidism](https://www.thyroid.org/hyperthyroidism/). 25. Harvard Medical School, Harvard Health Publishing. [5 overlooked symptoms that may signal heart trouble](https://www.health.harvard.edu/heart-health/5-overlooked-symptoms-that-may-signal-heart-trouble). 26. National Institutes of Health, National Heart, Lung, and Blood Institute. [Circadian rhythm disorders](https://www.nhlbi.nih.gov/health/circadian-rhythm-disorders). 27. National Institutes of Health, National Heart, Lung, and Blood Institute. [Insomnia](https://www.nhlbi.nih.gov/health/insomnia). 28. de Oliveira MM, Conti C, Prado GF. [Pharmacological treatment for Kleine-Levin syndrome](https://doi.org/10.1002/14651858.cd006685.pub4). Cochrane Database Syst Rev. 2016;2016(5):CD006685. doi:10.1002/14651858.CD006685.pub4 29. National Organization for Rare Disorders. [Narcolepsy](https://rarediseases.org/rare-diseases/narcolepsy/). 30. National Institute of Neurological Disorders and Stroke. [Restless legs syndrome](https://www.ninds.nih.gov/health-information/disorders/restless-legs-syndrome). 31. Mount Sinai. [Restless leg syndrome and related disorders](https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders). 32. Raheem OA, Orosco RK, Davidson TM, Lakin C. [Clinical predictors of nocturia in the sleep apnea population](https://doi.org/10.4103/0974-7796.127019). Urol Ann. 2014;6(1):31-5. doi:10.4103/0974-7796.127019 33. Harvard Medical School, Harvard Health Publishing. [What to do when medication makes you sleepy](https://www.health.harvard.edu/medications/what-to-do-when-medication-makes-you-sleepy#:~:text=Common%20culprits%20that%20cause%20sleepiness,to%20treat%20high%20blood%20pressure%2C). ![Brandon Peters, M.D.]() ![Brandon Peters, M.D.](https://www.verywellhealth.com/thmb/BbtKTL7wVNFD-4Y2KIj4azA0HpE=/144x144/filters:no_upscale\(\):max_bytes\(150000\):strip_icc\(\)/BrandonPetersMD_1000-5143e542c3084368b1220c4b86ede01c.png) By [Brandon Peters, MD](https://www.verywellhealth.com/brandon-peters-md-3014640) Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine. [See Our Editorial Process](https://www.verywellhealth.com/verywell-editorial-process-4777042) [Meet Our Medical Expert Board](https://www.verywellhealth.com/meet-our-medical-expert-board-11762003) Share Feedback Was this page helpful? Thanks for your feedback\! What is your feedback? 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Readable Markdown	### Key Takeaways - Fatigue can be caused by medical conditions like sleep apnea, diabetes, or thyroid disease. - Poor sleep habits, such as not getting enough sleep or having an uncomfortable sleeping environment, can make you tired. - Lifestyle choices, such as unhealthy diet, dehydration, and lack of exercise, can decrease your energy levels. The causes of constant tiredness and fatigue can stem from various factors that affect your energy levels throughout the day. These causes typically fall into four categories: lifestyle factors, medical conditions, sleep disorders, and mental health issues. Verywell / Cindy Chung 1:39 ### Click Play to Learn What You Can Do to Feel Less Tired ## Everyday Habits That Can Make You Tired Your daily habits can significantly affect how alert and energetic you feel throughout the day. Consider discussing the following factors with your healthcare provider: - Diet: Your body gets energy from food. An unbalanced diet or skipping meals can make you feel tired. Diet-related causes of fatigue include deficiencies in zinc, vitamin B12, or vitamin D, blood sugar changes, excessive alcohol, and too much caffeine. - [Dehydration](https://www.verywellhealth.com/diseases-that-cause-dehydration-in-adults-8679450): Dehydration occurs when you lose more fluids than you take in. Since water makes up 50% to 60% of your body weight, sweating, urination, heat, or illness can quickly deplete your hydration levels. While drinking eight 8-ounce glasses of water daily is a common guideline, very pale yellow or clear urine generally indicates proper hydration. - Poor sleep habits: Daytime fatigue may result from not getting enough quality sleep. Poor habits like sleeping in a noisy or uncomfortable environment, skipping a bedtime routine, exercising too close to bedtime, or napping late in the day can disrupt your rest. Additionally, not meeting the sleep needs for your age (eight to nine hours a night for adults ages 18 to 60) can leave you feeling tired. - [Inactive lifestyle](https://www.verywellhealth.com/sitting-down-8629219): Sitting for long periods can lead to restless and poor-quality sleep. Engaging in regular physical activity can improve your sleep and mental well-being. One study found that participants who exercised for 150 minutes a week experienced less insomnia, depression, and anxiety compared to those who were less active.. - Overexertion: Overexerting yourself through excessive exercise or other activities can leave your body too depleted to recover. This can lead to fatigue, poor sleep, and low motivation. Symptoms of overexertion may include mood swings, sore limbs, frequent illness, and a decline in performance at work or home. - [Stress](https://www.verywellhealth.com/psychological-stress-5205714): Stress can disrupt your sleep, and poor sleep can increase stress and fatigue. A survey found 43% of adults lost sleep due to stress, and 37% reported feeling tired because of it. Getting quality sleep helps maintain a positive mood during stressful times and increases joy from good experiences. ## Could a Health Condition Be Draining Your Energy? Feeling fatigued, weak, or sleepy can be symptoms of various medical conditions that impact your energy. Daytime sleepiness may be linked to these underlying causes: - [Anemia](https://www.verywellhealth.com/anemia-symptoms-4628300): Anemia is a condition in which your body has fewer red blood cells or they don't function properly, reducing the blood's ability to deliver oxygen to your organs. This can cause symptoms like fatigue, headaches, difficulty concentrating, irritability, and numbness in the hands and feet. The most common type is iron-deficiency anemia, but other causes include inherited disorders, chronic illnesses, and pregnancy. - Autoimmune disease: Autoimmune diseases occur when your immune system mistakenly attacks your own body, causing tissue damage and chronic inflammation. Conditions like rheumatoid arthritis, lupus, multiple sclerosis, and [inflammatory bowel disease](https://www.verywellhealth.com/ibd-crohns-colitis-overview-4581950) can lead to fatigue and disrupt your metabolism, nervous system, and sleep patterns. They may also cause imbalances in cytokines, proteins that regulate inflammation, mood, and sleep. - Cancer: More than 80% of people with cancer experience [cancer-related fatigue](https://www.verywellhealth.com/is-fatigue-a-symptom-of-cancer-514435), which often doesn't improve with rest and can be an early sign of the disease. Fatigue can result from low blood counts, disturbed electrolytes, altered hormone or cytokine levels, and changes in cell function caused by cancer. Treatments like chemotherapy, immunotherapy, and radiation can also contribute to fatigue. - [Chronic fatigue syndrome](https://www.verywellhealth.com/understanding-chronic-fatigue-syndrome-4158459): Chronic fatigue syndrome (ME/CFS) causes extreme fatigue that worsens with minimal exertion, doesn't improve with rest, and often includes flu-like symptoms and cognitive issues like "brain fog." The exact cause is unknown, but it may be linked to infections, chronic stress, autoimmune responses, or cytokine-related inflammation. - [Chronic obstructive pulmonary disease](https://www.verywellhealth.com/copd-4014741) (COPD): This chronic disease causes wheezing, shortness of breath, and extra mucus, making it hard to breathe. Fatigue is common in COPD, but it may not always be directly linked to breathing difficulties. The disease progresses over time, and it is especially common in current or former smokers. - Depression: This mood disorder causes sadness, loss of interest, and physical symptoms like fatigue. Daytime sleepiness may result from insomnia or other sleep problems often linked to depression, and fatigue may serve as an early warning sign. Biochemical similarities between depression and ME/CFS might explain fatigue as a shared symptom. - [Diabetes](https://www.verywellhealth.com/undiagnosed-diabetes-5179188): Diabetes fatigue syndrome refers to persistent fatigue experienced by people with diabetes. Possible causes include low blood sugar, hormonal imbalances, treatment side effects, overlapping conditions, and lifestyle factors like diet. - [Fibromyalgia](https://www.verywellhealth.com/fibromyalgia-7369351): Fibromyalgia is a chronic pain condition. It's caused by dysfunction in the central nervous system, which heightens sensitivity and turns harmless sensations into pain (allodynia). Fatigue is also a key symptom of fibromyalgia. This fatigue may be due to biochemical changes, inflammation, sleep disorders, and sleep disruptions. - Heart disease: If you have fatigue that's new and constant, it may be an early warning sign of heart failure or, less often, [coronary artery disease](https://www.verywellhealth.com/heart-disease-7481236). These conditions limit the amount of oxygen-rich blood that gets to your muscles or to the heart itself. Your heart and brain need oxygen. When you have heart disease, your body limits the blood sent to less important parts like the limbs, leading to reduced energy and fatigue. - Infections: Fatigue is common during and after infectious illnesses like COVID-19, influenza, mononucleosis, and [Lyme disease](https://www.verywellhealth.com/lyme-disease-7151644). While tiredness often resolves as the illness clears, some people experience lingering fatigue, known as post-viral fatigue or, [in the case of COVID-19, long COVID](https://www.verywellhealth.com/nicotine-patches-long-covid-treatment-8705089). Researchers are exploring links between these persistent symptoms and conditions like ME/CFS, especially for viruses like Epstein-Barr, which can reactivate and contribute to fatigue and autoimmune diseases. - [Food allergies and intolerances](https://www.verywellhealth.com/most-common-food-sensitivities-1944845): Food allergies and intolerances can cause fatigue by triggering immune responses or gastrointestinal distress that depletes energy levels. Reactions to allergens, such as dairy, gluten, or nuts, may lead to inflammation, poor nutrient absorption, or disrupted sleep. Chronic exposure to problematic foods can worsen fatigue over time, especially if the underlying issue goes unaddressed. - [Kidney disease](https://www.verywellhealth.com/acute-vs-chronic-kidney-disease-5221287): Kidney disease can cause fatigue due to the buildup of toxins in the blood when the kidneys are not functioning properly. This can lead to anemia, as the kidneys produce less erythropoietin, a hormone essential for red blood cell production. Electrolyte imbalances and reduced nutrient absorption may also contribute to low energy levels. - [Menopause](https://www.verywellhealth.com/side-effects-of-menopause-5217701): The transition to menopause, including perimenopause and the early post-menopausal stage, often brings fatigue along with symptoms like hot flashes, night sweats, and mood swings. Fatigue may stem from sleep disruptions, hormonal changes, aging, or stress. - [Pregnancy](https://www.verywellhealth.com/pregnancy-facts-and-statistics-5324188): Pregnancy places extra demands on the body, often causing fatigue, especially during the first and third trimesters. Factors contributing to this tiredness include the energy required to support the baby, hormonal changes, low blood sugar or pressure, and disrupted sleep. Stress and digestive changes can also play a role in pregnancy-related exhaustion. - [Thyroid disease](https://www.verywellhealth.com/hypothyroidism-hyperthyroidism-5180646): Thyroid hormone imbalances, whether high (hyperthyroidism) or low (hypothyroidism), can cause fatigue due to their effects on metabolism. Hyperthyroidism speeds up bodily processes, leading to symptoms like anxiety, sleep disruption, and eventual exhaustion as energy reserves deplete, while hypothyroidism slows everything down, causing fatigue alongside weight gain, depression, and memory problems. ### Recognizing a Heart Attack A heart attack requires immediate medical attention. Call 9-1-1 if you or someone else suddenly experiences: - Chest pain or pressure, which can also be in the upper abdomen - Pain that spreads to the jaw, neck, back, arms, or stomach - Shortness of breath - Dizziness or fainting - Nausea or vomiting - Extreme fatigue ## How Sleep Disorders Affect Your Energy Levels Various circadian rhythm disorders can leave you [feeling too sleepy during the day](https://www.verywellhealth.com/why-am-i-sleepy-after-eating-lunch-3014827). The circadian rhythm is your body's natural clock. It helps to coordinate your activities based on when it's light and dark in your environment. If your internal timing is misaligned, you may find yourself with excessive daytime sleepiness. Six common circadian rhythm disorders include: - Advanced sleep phase syndrome: The distinguishing feature is falling asleep and waking up earlier than you want, usually by about three hours. - Delayed sleep phase syndrome: This causes difficulty falling asleep and makes it extremely hard to wake up. - Irregular sleep-wake rhythm: This occurs when the circadian rhythm becomes completely disconnected from the natural day-night cycle. Sleep is fragmented, with short spells scattered throughout the day. - Jet lag: A temporary rhythm disorder associated with travel across several time zones. To adjust, it may take one day for every time zone you cross. - Non-entrained (non-24) disorder: This usually occurs in visually impaired people. The sleep cycle is typically a little longer than average and thus becomes more out of sync every day. - Shift-work sleep disorder: Poor sleep is caused by working at night and sleeping during the day. This can lead to increased accidents and possibly a higher risk of some forms of cancer. Other sleep disorders that can result in constant tiredness or fatigue include: - [Insomnia](https://www.verywellhealth.com/what-is-insomnia-the-features-symptoms-and-causes-3014805): Insomnia, which makes it hard to fall or stay asleep, can be occasional or a chronic issue that causes constant fatigue. It may result from factors like genetics, irregular sleep schedules, stimulants, alcohol, drug use, or high stress levels. Environmental factors, sedentary lifestyles, and excessive light exposure, especially from screens before bed, can also contribute. - Kleine-Levin syndrome: Kleine-Levin syndrome, a rare condition primarily affecting young men, causes recurrent episodes of excessive sleepiness that can last days to months and be severely debilitating. These episodes often disrupt daily life and school, with symptoms including hallucinations, hypersexual or compulsive behaviors, binge eating, and mood or cognitive disturbances. - [Narcolepsy](https://www.verywellhealth.com/restless-sleep-symptoms-causes-and-treatment-5649715): Narcolepsy disrupts the body's ability to regulate sleep, causing sudden sleep attacks during the day and wakefulness elements during sleep. Key symptoms include cataplexy, a sudden loss of muscle control triggered by emotions, and vivid hallucinations during sleep transitions. Sleep paralysis, frequent nighttime awakenings, and performing actions during sleep attacks without memory of them are also common. - [Restless leg syndrome](https://www.verywellhealth.com/restless-leg-syndrome-1746081) (RLS): Disorders causing excessive movements during sleep, like RLS, can disrupt sleep and lead to daytime fatigue. RLS creates an uncomfortable sensation in the legs and an urge to move, typically worsening in the evening or when lying down. Movement temporarily relieves the discomfort but can interfere with restful sleep. - [Periodic limb movement syndrome](https://www.verywellhealth.com/types-of-sleep-disorders-8778367) (PLMS): This condition related to RLS involves sudden jerking movements that occur during sleep. These may be repetitive, disturbing your sleep and potentially that of your bed partner. - [Sleep apnea](https://www.verywellhealth.com/effects-of-sleep-apnea-5215939): Sleep apnea causes repeated pauses in breathing during sleep, often followed by loud snorts or gasps that disrupt sleep cycles. These interruptions shift you into lighter sleep stages, leaving you tired even if you don't recall waking. Symptoms include snoring, morning dry mouth or headaches, teeth grinding, sexual dysfunction, and frequent nighttime urination. ### Warning: Risk of Fatal Complications Sleep apnea puts a strain on your heart. It can lead to high blood pressure, cardiomyopathy (enlarged muscle tissue in the heart), heart failure, heart attack, and stroke. This makes proper diagnosis and treatment of sleep apnea especially important. ## Medications That Cause Drowsiness Drowsiness and fatigue are common side effects of medications. If you have daytime tiredness, your healthcare provider will likely look into what medications you're taking. Drugs that can make you tired include: - Analgesics: Painkillers including opioids such as Vicodin (hydrocodone-acetaminophen), OxyContin (oxycodone) - Antiseizure medications (ASMs): Seizure prevention drugs such as Neurontin (gabapentin) and Lyrica (pregabalin) - Antidepressants: Tricyclics and SSRIs/SNRIs including amitriptyline, Prozac (fluoxetine), Cymbalta (duloxetine) - Antiemetics: Drugs for nausea, vomiting, and motion sickness such as Dramamine (dimenhydrinate), Zyprexa (olanzapine), Reglan (metoclopramide) - Antihistamines: Allergy medications including Zyrtec (cetirizine), Claritin (loratadine), Benadryl (diphenhydramine) - Antipsychotics: Drugs for schizophrenia, psychosis in bipolar disorder, depression, and [Alzheimer's diseas](https://www.verywellhealth.com/alzheimers-disease-7111202)e including [Abilify (aripiprazole)](https://www.verywellhealth.com/how-long-does-it-take-for-abilify-to-work-8553110), Risperdal (risperidone), Seroquel (quetiapine) - Benzodiazepines: Tranquilizers and sedatives such as Librium (chlordiazepoxide), Valium (diazepam) - Blood pressure drugs: Diuretics, ARBs, calcium channel blockers, beta-blockers including Lasix (furosemide), Avapro (irbesartan), verapamil HCL, Toprol-XL (metoprolol succinate) - Muscle relaxants: Including Soma (carisoprodol), Lorzone (chlorzoxazone), Amrix (cyclobenzaprine) - Sedatives: Non-benzodiazepine sedative/hypnotics such as Ambien (zolpidem), Sonata (zaleplon), Lunesta (eszopiclone) - Statins: Especially fat-soluble drugs including Lipitor (atorvastatin), lovastatin, Vytorin (ezetimibe/simvastatin), Zocor (simvastatin) - Steroids: Used for inflammation, allergies, skin diseases, certain cancers, and after organ transplants. Some may cause insomnia, including prednisolone, methylprednisolone, and dexamethasone. 33 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our [editorial process](https://www.verywellhealth.com/verywell-editorial-process-4777042) to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. 1. Sejbuk M, Mirończuk-Chodakowska I, Witkowska AM. [Sleep quality: A narrative review on nutrition, stimulants, and physical activity as important factors](https://doi.org/10.3390%2Fnu14091912). Nutrients. 2022;14(9):1912. doi:10.3390/nu14091912 2. Harvard Health Publishing. [Fight fatigue with fluids](https://www.health.harvard.edu/healthbeat/fight-fatigue-with-fluids). 3. National Institutes of Health, National Institute on Aging. [Fatigue in older adults](https://www.nia.nih.gov/health/fatigue/fatigue-older-adults). 4. Hartescu I, Morgan K, Stevinson CD. [Increased physical activity improves sleep and mood outcomes in inactive people with insomnia: A randomized controlled trial](https://doi.org/10.1111/jsr.12297). J Sleep Res. 2015;24(5):526-534. doi:10.1111/jsr.12297 5. National Institutes of Health, U.S. National Library of Medicine: MedlinePlus. [Are you getting too much exercise?](https://medlineplus.gov/ency/patientinstructions/000807.htm) 6. American Psychological Association. [Stress and sleep](https://www.apa.org/news/press/releases/stress/2013/sleep). 7. Sin NL, Wen JH, Klaiber P, Buxton OM, Almeida DM. [Sleep duration and affective reactivity to stressors and positive events in daily life](https://doi.org/10.1037/hea0001033). Health Psychol. 2020; doi:10.1037/hea0001033 8. University of Pennsylvania. Penn Medicine. [What Is Anemia?](https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/anemia) 9. Zielinski MR, Systrom DM, Rose NR. [Fatigue, sleep, and autoimmune and related disorders](https://doi.org/10.3389/fimmu.2019.01827). Front Immunol. 2019;10:1827. doi:10.3389/fimmu.2019.01827 10. American Cancer Society. [What is fatigue or weakness?](https://www.cancer.org/cancer/managing-cancer/side-effects/fatigue/what-is-cancer-related-fatigue.html) 11. Sotzny F, Blanco J, Capelli E, et al. [Myalgic encephalomyelitis/chronic fatigue syndrome - Evidence for an autoimmune disease](https://doi.org/10.1016/j.autrev.2018.01.009). Autoimmun Rev. 2018;17(6):601-609. doi:10.1016/j.autrev.2018.01.009 12. Goërtz YMJ, Spruit MA, Van 't Hul AJ, et al. [Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation](https://doi.org/10.1177/1753466619878128). Ther Adv Respir Dis. 2019;13:1753466619878128. doi:10.1177/1753466619878128 13. Corfield EC, Martin NG, Nyholt DR. [Co-occurrence and symptomatology of fatigue and depression](https://doi.org/10.1016/j.comppsych.2016.08.004). Compr Psychiatry. 2016;71:1-10. doi:10.1016/j.comppsych.2016.08.004 14. Allen J, Romay-Tallon R, Brymer KJ, Caruncho HJ, Kalynchuk LE. [Mitochondria and mood: Mitochondrial dysfunction as a key player in the manifestation of depression](https://doi.org/10.3389/fnins.2018.00386). Front Neurosci. 2018;12:386. doi:10.3389/fnins.2018.00386 15. Kalra S, Sahay R. [Diabetes fatigue syndrome](https://doi.org/10.1007/s13300-018-0453-x). Diabetes Ther. 2018;9(4):1421-1429. doi:10.1007/s13300-018-0453-x 16. Littlejohn G, Guymer E. [Key milestones contributing to the understanding of the mechanisms underlying fibromyalgia](https://doi.org/10.3390/biomedicines8070223). Biomedicines. 2020;8(7):223. doi:10.3390/biomedicines8070223 17. Wostyn P. [COVID-19 and chronic fatigue syndrome: Is the worst yet to come?](https://doi.org/10.1016/j.mehy.2020.110469). Med Hypotheses. 2021;146:110469. doi:10.1016/j.mehy.2020.110469 18. Kerr JR. [Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors](https://doi.org/10.1136/jclinpath-2019-205822). J Clin Pathol. 2019;72(10):651-658. doi:10.1136/jclinpath-2019-205822 19. Pasta A, Formisano E, Calabrese F, et al. [Food intolerances, food allergies, and IBS: Lights and shadows](https://doi.org/10.3390/nu16020265). Nutrients. 2024;16(2):265. doi:10.3390/nu16020265 20. National Institute of Diabetes and Digestive and Kidney Diseases. [Anemia in chronic kidney disease](https://www.niddk.nih.gov/health-information/kidney-disease/anemia). 21. Taylor-Swanson L, Wong AE, Pincus D, et al. [The dynamics of stress and fatigue across menopause: Attractors, coupling, and resilience](https://doi.org/10.1097/gme.0000000000001025). Menopause. 2018;25(4):380-390. doi:10.1097/GME.0000000000001025 22. Bai G, Korfage IJ, Groen EH, Jaddoe VW, Mautner E, Raat H. [Associations between Nausea, Vomiting, Fatigue and Health-Related Quality of Life of Women in Early Pregnancy: The Generation R Study](https://doi.org/10.1371%2Fjournal.pone.0166133). PLoS One. 2016 Nov 4;11(11):e0166133. doi: 10.1371/journal.pone.0166133 23. Harvard Medical School, Harvard Health Publishing. [The lowdown on thyroid slowdown](https://www.health.harvard.edu/newsletter_article/the-lowdown-on-thyroid-slowdown). 24. American Thyroid Association. [Hyperthyroidism](https://www.thyroid.org/hyperthyroidism/). 25. Harvard Medical School, Harvard Health Publishing. [5 overlooked symptoms that may signal heart trouble](https://www.health.harvard.edu/heart-health/5-overlooked-symptoms-that-may-signal-heart-trouble). 26. National Institutes of Health, National Heart, Lung, and Blood Institute. [Circadian rhythm disorders](https://www.nhlbi.nih.gov/health/circadian-rhythm-disorders). 27. National Institutes of Health, National Heart, Lung, and Blood Institute. [Insomnia](https://www.nhlbi.nih.gov/health/insomnia). 28. de Oliveira MM, Conti C, Prado GF. [Pharmacological treatment for Kleine-Levin syndrome](https://doi.org/10.1002/14651858.cd006685.pub4). Cochrane Database Syst Rev. 2016;2016(5):CD006685. doi:10.1002/14651858.CD006685.pub4 29. National Organization for Rare Disorders. [Narcolepsy](https://rarediseases.org/rare-diseases/narcolepsy/). 30. National Institute of Neurological Disorders and Stroke. [Restless legs syndrome](https://www.ninds.nih.gov/health-information/disorders/restless-legs-syndrome). 31. Mount Sinai. [Restless leg syndrome and related disorders](https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders). 32. Raheem OA, Orosco RK, Davidson TM, Lakin C. [Clinical predictors of nocturia in the sleep apnea population](https://doi.org/10.4103/0974-7796.127019). Urol Ann. 2014;6(1):31-5. doi:10.4103/0974-7796.127019 33. Harvard Medical School, Harvard Health Publishing. [What to do when medication makes you sleepy](https://www.health.harvard.edu/medications/what-to-do-when-medication-makes-you-sleepy#:~:text=Common%20culprits%20that%20cause%20sleepiness,to%20treat%20high%20blood%20pressure%2C). ![Brandon Peters, M.D.](https://www.verywellhealth.com/thmb/BbtKTL7wVNFD-4Y2KIj4azA0HpE=/144x144/filters:no_upscale\(\):max_bytes\(150000\):strip_icc\(\)/BrandonPetersMD_1000-5143e542c3084368b1220c4b86ede01c.png) By [Brandon Peters, MD](https://www.verywellhealth.com/brandon-peters-md-3014640) Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine. Was this page helpful? Thanks for your feedback\! What is your feedback?
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