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| Meta Description | Considering melatonin supplements to help you sleep? We break down benefits, risks, side-effects, and how to choose the best product for you. |
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Key Takeaways
Melatonin is a hormone that regulates the sleep-wake cycle.
Supplementary melatonin can help you fall asleep or adjust to new time zones.
Experts recommend a dosage of 1 to 5 milligrams of melatonin about 30 minutes before bed.
Consult your doctor before taking melatonin or giving it to children.
Exogenous melatonin—a synthetic version of the body’s natural sleep hormone—has grown increasingly popular as a sleep aid over the last two decades. Nearly two thirds of American adults have taken melatonin supplements, and use among children and adolescents is also on the rise.
While scientific evidence suggests that
melatonin supplements
may help some people fall asleep more easily, this over-the-counter sleep aid is not a cure-all for sleep difficulties. Before using these supplements, it is important to understand how melatonin works, when it is most likely to be beneficial, and when to talk to your doctor.
Melatonin
is a naturally occurring hormone that helps regulate the body’s
circadian rhyt
h
ms
, which are biological patterns that operate on a 24-hour clock. Specifically, melatonin plays a vital role in the sleep-wake cycle.
For a healthy individual with a normal sleep-wake cycle, the body begins producing melatonin every evening around the time sun goes down. This causes a gradual increase in sleepiness. Melatonin production continues into the night, peaking about seven hours after sunset. This helps the person stay asleep through the night. In the morning, melatonin drops to undetectable levels, as
exposure to light
inhibits production of the sleep hormone. This helps a person feel alert upon waking.
For some people who have difficulty falling asleep, taking supplemental melatonin
about 30 minutes
before bedtime may help. Supplementing naturally produced melatonin can reinforce circadian rhythms and signal to the body that it’s time to sleep. For this reason, melatonin supplements may be a good choice for individuals who:
Have naturally low levels of melatonin
Temporarily struggle to fall asleep due to circumstances such as
stress
or
jet lag
Â
Take medications that interfere with sleep
Are night owls but
need to wake early
Â
How Melatonin Can Get You More Sleep
Melatonin for Sleep Disorders
Melatonin supplements are likely to benefit people with sleep disorders that affect their circadian rhythms. Supplemental melatonin may also benefit people with other types of sleep disorders, though results tend to be more variable and less impactful and prescription medications may be necessary.
Non-24-hour sleep-wake rhythm disorder (N24SWD):
People with
N24SWD
, most of whom are blind, have circadian rhythms that do not synchronize with the 24-hour cycle of day and night.
Taking melatonin an hour before bedtime
can help align a person’s circadian clock with their environment, even in the absence of light and darkness.
Delayed sleep-wake phase disorder (DSWPD):
People with
DSWPD
, which mainly affects adolescents and young adults, aren’t able to fall asleep until long after conventional or desired bedtimes. While melatonin supplements aren’t a first-line treatment for DSWPD, they may help people with the disorder
fall asleep earlier.
Insomnia:
Melatonin is not typically prescribed as the sole treatment for
insomnia
, but it may be used alongside other therapies to help reduce the amount of time it takes to fall asleep at bedtime.
Shift work disorder:
Small doses of melatonin may help
people who work rotating or night shifts
fall asleep more easily during the day. However, some experts warn against taking melatonin for this purpose, as it can be difficult for shift workers to effectively time its administration or to predict its effect
s
.
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Melatonin for Kids
Research on the safety and efficacy of sleep aids for children is limited, so caregivers should not administer melatonin supplements to children
unless a doctor has instructed them to do so.
Supplemental melatonin may be appropriate for children and adolescents with particular sleep, behavioral, and developmental disorders.
Melatonin supplements are rarely the right choice for children under the age of 5, whose sleep problems tend to be behavioral in nature and can often be resolved by establishing
healthy sleep habits
and adjusting sleep environments. Additionally, melatonin should not be used to enhance sleep in children who don’t have sleep problems or to force them to go to bed earlier.Â
Accidental overdoses of melatonin supplements by children have been on the rise. It is vital that caregivers administer melatonin
according to instructions provided by a doctor
and safely store melatonin supplements out of the reach of children.
While research suggests that short-term use of melatonin is safe for most adults, more studies are needed to confirm its long-term safety. Unlike some sleep aids, melatonin supplements are not believed to be habit-forming, and they have
relatively mild side effects.
Possible Interactions
Before you begin taking melatonin supplements, make sure to talk to your doctor about potential interactions that could compromise your health. Melatonin supplements have the potential to interact with medications and are generally not recommended for people who:
Are pregnant or breastfeeding
Have a bleeding disorder
Experience depression
Have seizures
Are recipients of an organ transplant
Some medications—including
birth control pills
, certain serotonin reuptake inhibitors (SSRIs), and caffeine—might intensify the effects of melatonin supplements. Additionally, combining melatonin supplements with certain medications can reduce their effectiveness of the medications or produce unwanted side effects.Â
Over-the-counter supplements may contain as little as .2 milligrams or as much as 20 milligrams of melatonin. They also come in an array of formulations, including slow- and fast-release pills,
gummies
, dissolvable tablets, liquids, gels, creams, and
patches
. Given the variety of available options, it’s important to talk to a doctor about the best choice for you.
The ideal
melatonin dosage
for you will depend on the sleep problem you’re treating, as well as your personal characteristics and health history. For adults and adolescents, doctors usually recommend dosages in the 1 to 5 milligram range.
Dosages for children
may range from .2 milligrams to three milligrams.Â
“More is not better when it comes to melatonin. Going above 2-3 mg likely won’t work any better than 1mg or less, but does increase one’s risk for side effects.”
Research indicates that melatonin dosages below 1 milligram may work just as well as higher doses. Unless directed otherwise by a doctor, it is best to start with the lowest possible dose and to increase as needed. Experts recommend taking no more than 10 milligrams per 24 hour period.
A complicating factor is the fact that
many melatonin supplements are mislabeled.
Recent studies have shown that the majority of melatonin products
do not contain the advertised dosage of the sleep hormone.
Tests have revealed that some products have significantly less melatonin than stated on the label, while others have
more than four times
the advertised amount of melatonin.
In the United States, melatonin is considered a dietary supplement, so the Food and Drug Administration (FDA) does not subject it to the same rigorous standards as pharmaceutical drugs. For this reason, melatonin users should exercise caution when considering their melatonin options.
To give yourself the best chance of getting a
high quality product
with accurate dosage of melatonin, try looking for a U.S. Pharmacopeia certification on the label (which ensures that the product has been vetted by an outside organization), asking your doctor or a pharmacist to suggest a trusted brand, or picking a low-dose option.
Alternatives to Melatonin
Melatonin isn’t the right choice for everyone. You may get the results you are looking for by cultivating healthy sleep habits, changing your sleeping environment, or addressing the root causes of your sleep difficulties.
Practice healthy sleep hygiene:
Committing to
healthy sleep practices
can help you sleep better. Try going to bed and getting up at the same time every day. Develop a relaxing bedtime routine. Exercise regularly, and avoid caffeine and alcohol in the evening.
Avoid screens in the hours before bedtime:
Phones, tablets, TVs, and other electronic devices with screens emit
blue light
, which inhibits melatonin production.
Enhance your sleep environment:
Make sure that your bedroom is cool, dark, and quiet. Consider purchasing a more
comfortable mattress
or
high quality sheets
.Â
Address underlying health concerns:
Many health problems can interfere with sleep. Treating conditions like chronic pain,
sleep apnea
, and acid reflux may help you get better sleep.
Focus on your mental health:
Stress, anxiety, and depression can all make it hard to sleep. Consider seeing a counselor, engaging in
relaxation exercises
, or asking for support from family and friends.
Try cognitive behavioral therapy for insomnia (CBT-I):
If you have insomnia, you might try CBT-I, which is an
effective insomnia treatment
. CBT-I involves addressing thought patterns and behaviors that interfere with sleep with the help of a licensed mental health professional.
Medical Disclaimer: The content on this page should not be taken as medical advice or used as a recommendation for any specific treatment or medication. Always consult your doctor before taking a new medication or changing your current treatment.
Still have questions? Ask our community!
Join our
Sleep Care Community
— a trusted hub of sleep health professionals, product specialists, and people just like you. Whether you need expert sleep advice for your insomnia or you’re searching for the perfect mattress, we’ve got you covered. Get personalized guidance from the experts who know sleep best.
Written By
Lucy Bryan,
Contributing Writer
Lucy Bryan is a writer and editor with more than a decade of experience in higher education. She holds a B. A. in journalism from the University of North Carolina at Chapel Hill and an M.F.A. in creative writing from Penn State University.
Medically Reviewed by
Dustin Cotliar, MD, MPH,
Physician
Dustin Cotliar, MD, holds a medical degree from the State University of NY (SUNY) Downstate College of Medicine, and a master’s in public health from Columbia University, where he focused on healthcare policy and management. He is board-certified in Emergency Medicine, with over eight years of practice that includes emergency medicine, urgent care, and telemedicine.
Learn more about our Editorial Team
References
9 Sources
Shane-McWhorter, L. (2023, January). Melatonin. Merck Manual Professional Version.
https://www.merckmanuals.com/professional/special-subjects/dietary-supplements/melatonin
Neubauer, D. (2024 February). Pharmacotherapy for insomnia in adults. In R. Benca, J. Elmore, & A. Eichler (Ed.). UpToDate.
https://www.uptodate.com/contents/pharmacotherapy-for-insomnia-in-adults#H2582713949
A.D.A.M. Medical Encyclopedia. (2023, October 18). Melatonin. MedlinePlus.
https://medlineplus.gov/druginfo/natural/940.html
Abbott, S. (2024, February). Non-24-hour sleep-wake rhythm disorder. In C. Goldstein & A. Eichler (Ed.). UpToDate.
https://www.uptodate.com/contents/non-24-hour-sleep-wake-rhythm-disorder
Auger, R. (2024, February). Delayed sleep-wake phase disorder. In C. Goldstein, R. Chervin, & A. Eichler (Ed.). UpToDate.
https://www.uptodate.com/contents/delayed-sleep-wake-phase-disorder
J. Owens. (2024, February). Pharmacotherapy for insomnia in children and adolescents: A rational approach. In R. Chervin & A. Eichler (Ed.). UpToDate.
https://www.uptodate.com/contents/pharmacotherapy-for-insomnia-in-children-and-adolescents-a-rational-approach
Salahub, C., Wu, P. E., Burry, L. D., Soong, C., Sheehan, K. A., MacMillan, T. E., & Lapointe-Shaw, L. (2022). Melatonin for Insomnia in Medical Inpatients: A Narrative Review. Journal of clinical medicine, 12(1), 256.
https://pubmed.ncbi.nlm.nih.gov/36615056
Erland, L. A., & Saxena, P. K. (2017). Melatonin natural health products and supplements: Presence of serotonin and significant variability of melatonin content. Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine, 13(2), 275–281.
https://pubmed.ncbi.nlm.nih.gov/27855744/
Cohen, P. A., Avula, B., Wang, Y. H., Katragunta, K., & Khan, I. (2023). Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US. JAMA, 329(16), 1401–1402.
https://pubmed.ncbi.nlm.nih.gov/37097362/ |
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# Melatonin: Usage, Side Effects, and Safety
Updated July 10, 2025
Written by Lucy Bryan

Lucy Bryan
Contributing Writer
Lucy Bryan is a writer and editor with more than a decade of experience in higher education. She holds a B. A. in journalism from the University of North Carolina at Chapel Hill and an M.F.A. in creative writing from Penn State University.
[Read Full Bio](https://www.sleepfoundation.org/about-us/who-we-are#lucy_bryan)
Want to read more about all our experts in the field?
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\| Medically Reviewed by Dustin Cotliar, MD, MPH

Dustin Cotliar, MD, MPH
Physician
Dustin Cotliar, MD, holds a medical degree from the State University of NY (SUNY) Downstate College of Medicine, and a master’s in public health from Columbia University, where he focused on healthcare policy and management. He is board-certified in Emergency Medicine, with over eight years of practice that includes emergency medicine, urgent care, and telemedicine.
[Read Full Bio](https://www.sleepfoundation.org/about-us/who-we-are#dustin_cotliar,_md,_mph)
Want to read more about all our experts in the field?
[Learn About The Editorial Team](https://www.sleepfoundation.org/about-us)
- [What Is Melatonin?](https://www.sleepfoundation.org/melatonin#what-is-melatonin--1)
- [Benefits of Melatonin for Sleep](https://www.sleepfoundation.org/melatonin#benefits)
- [Side Effects of Melatonin](https://www.sleepfoundation.org/melatonin#side-effects)
- [How Much Melatonin Should I Take?](https://www.sleepfoundation.org/melatonin#how-much)
- [How to Choose Melatonin Supplements](https://www.sleepfoundation.org/melatonin#how_to_choose)
Key Takeaways
- Melatonin is a hormone that regulates the sleep-wake cycle.
- Supplementary melatonin can help you fall asleep or adjust to new time zones.
- Experts recommend a dosage of 1 to 5 milligrams of melatonin about 30 minutes before bed.
- Consult your doctor before taking melatonin or giving it to children.
Exogenous melatonin—a synthetic version of the body’s natural sleep hormone—has grown increasingly popular as a sleep aid over the last two decades. Nearly two thirds of American adults have taken melatonin supplements, and use among children and adolescents is also on the rise.
While scientific evidence suggests that [melatonin supplements](https://www.sleepfoundation.org/melatonin/best-melatonin-supplements) may help some people fall asleep more easily, this over-the-counter sleep aid is not a cure-all for sleep difficulties. Before using these supplements, it is important to understand how melatonin works, when it is most likely to be beneficial, and when to talk to your doctor.
[Our Top Melatonin Supplement We’ve tried a lot of melatonin supplements and we’ve even made our own. The ones from Momentous are our favorite. From Our Partners at SleepDoctor.com. Shop at Sleep Doctor](https://sleepdoctor.com/products/elite-sleep)
## What Is Melatonin?
Melatonin [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) Merck ManualFirst published in 1899 as a small reference book for physicians and pharmacists, the Manual grew in size and scope to become one of the most widely used comprehensive medical resources for professionals and consumers.[View Source](https://www.sleepfoundation.org/melatonin#references-181964) is a naturally occurring hormone that helps regulate the body’s [circadian rhyt](https://www.sleepfoundation.org/circadian-rhythm)[h](https://www.sleepfoundation.org/circadian-rhythm)[ms](https://www.sleepfoundation.org/circadian-rhythm), which are biological patterns that operate on a 24-hour clock. Specifically, melatonin plays a vital role in the sleep-wake cycle.
For a healthy individual with a normal sleep-wake cycle, the body begins producing melatonin every evening around the time sun goes down. This causes a gradual increase in sleepiness. Melatonin production continues into the night, peaking about seven hours after sunset. This helps the person stay asleep through the night. In the morning, melatonin drops to undetectable levels, as [exposure to light](https://www.sleepfoundation.org/bedroom-environment/light-and-sleep) inhibits production of the sleep hormone. This helps a person feel alert upon waking.

###
[Is It Safe to Take Melatonin Every Night?](https://www.sleepfoundation.org/melatonin/is-it-safe-to-take-melatonin-every-night)
[Is Melatonin Bad for You?](https://www.sleepfoundation.org/melatonin/is-melatonin-bad-for-you)
[How Long Does Melatonin Last?](https://www.sleepfoundation.org/melatonin/how-long-does-melatonin-last)
[How Long Does Melatonin Take to Work?](https://www.sleepfoundation.org/melatonin/how-long-does-melatonin-take-to-work)
[Does Melatonin Expire?](https://www.sleepfoundation.org/melatonin/does-melatonin-expire)
## Benefits of Melatonin for Sleep
For some people who have difficulty falling asleep, taking supplemental melatonin about 30 minutes [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) UpToDateMore than 2 million healthcare providers around the world choose UpToDate to help make appropriate care decisions and drive better health outcomes. UpToDate delivers evidence-based clinical decision support that is clear, actionable, and rich with real-world insights.[View Source](https://www.sleepfoundation.org/melatonin#references-253039) before bedtime may help. Supplementing naturally produced melatonin can reinforce circadian rhythms and signal to the body that it’s time to sleep. For this reason, melatonin supplements may be a good choice for individuals who:
- Have naturally low levels of melatonin [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) Medline PlusMedlinePlus is an online health information resource for patients and their families and friends.[View Source](https://www.sleepfoundation.org/melatonin#references-253041)
- Temporarily struggle to fall asleep due to circumstances such as [stress](https://www.sleepfoundation.org/insomnia/stress-and-insomnia) or [jet lag](https://www.sleepfoundation.org/travel-and-sleep/jet-lag)
- Take medications that interfere with sleep
- Are night owls but [need to wake early](https://www.sleepfoundation.org/sleep-faqs/how-to-become-a-morning-person)
###
- [How Melatonin Can Get You More Sleep](https://www.sleepfoundation.org/melatonin/melatonin-benefits)
### Melatonin for Sleep Disorders
Melatonin supplements are likely to benefit people with sleep disorders that affect their circadian rhythms. Supplemental melatonin may also benefit people with other types of sleep disorders, though results tend to be more variable and less impactful and prescription medications may be necessary.
- **Non-24-hour sleep-wake rhythm disorder (N24SWD):** People with [N24SWD](https://www.sleepfoundation.org/non-24-sleep-wake-disorder/symptoms-diagnosis), most of whom are blind, have circadian rhythms that do not synchronize with the 24-hour cycle of day and night. Taking melatonin an hour before bedtime [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) UpToDateMore than 2 million healthcare providers around the world choose UpToDate to help make appropriate care decisions and drive better health outcomes. UpToDate delivers evidence-based clinical decision support that is clear, actionable, and rich with real-world insights.[View Source](https://www.sleepfoundation.org/melatonin#references-252209) can help align a person’s circadian clock with their environment, even in the absence of light and darkness.
- **Delayed sleep-wake phase disorder (DSWPD):** People with [DSWPD](https://www.sleepfoundation.org/delayed-sleep-wake-phase-syndrome), which mainly affects adolescents and young adults, aren’t able to fall asleep until long after conventional or desired bedtimes. While melatonin supplements aren’t a first-line treatment for DSWPD, they may help people with the disorder fall asleep earlier. [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) UpToDateMore than 2 million healthcare providers around the world choose UpToDate to help make appropriate care decisions and drive better health outcomes. UpToDate delivers evidence-based clinical decision support that is clear, actionable, and rich with real-world insights.[View Source](https://www.sleepfoundation.org/melatonin#references-253043)
- **Insomnia:** Melatonin is not typically prescribed as the sole treatment for [insomnia](https://www.sleepfoundation.org/insomnia), but it may be used alongside other therapies to help reduce the amount of time it takes to fall asleep at bedtime.
- **Shift work disorder:** Small doses of melatonin may help [people who work rotating or night shifts](https://www.sleepfoundation.org/shift-work-disorder) fall asleep more easily during the day. However, some experts warn against taking melatonin for this purpose, as it can be difficult for shift workers to effectively time its administration or to predict its effect**s**.
## Say Goodbye to Insomnia
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### Melatonin for Kids
Research on the safety and efficacy of sleep aids for children is limited, so caregivers should not administer melatonin supplements to children unless a doctor has instructed them to do so. [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) UpToDateMore than 2 million healthcare providers around the world choose UpToDate to help make appropriate care decisions and drive better health outcomes. UpToDate delivers evidence-based clinical decision support that is clear, actionable, and rich with real-world insights.[View Source](https://www.sleepfoundation.org/melatonin#references-253045)
Supplemental melatonin may be appropriate for children and adolescents with particular sleep, behavioral, and developmental disorders.
Melatonin supplements are rarely the right choice for children under the age of 5, whose sleep problems tend to be behavioral in nature and can often be resolved by establishing [healthy sleep habits](https://www.sleepfoundation.org/children-and-sleep/sleep-strategies-kids) and adjusting sleep environments. Additionally, melatonin should not be used to enhance sleep in children who don’t have sleep problems or to force them to go to bed earlier.
###
- [Melatonin for Kids](https://www.sleepfoundation.org/melatonin/melatonin-for-children)
- [Melatonin Dosage for Kids](https://www.sleepfoundation.org/melatonin/melatonin-dosage-for-kids)
Accidental overdoses of melatonin supplements by children have been on the rise. It is vital that caregivers administer melatonin **according to instructions provided by a doctor** and safely store melatonin supplements out of the reach of children.
## Side Effects of Melatonin
While research suggests that short-term use of melatonin is safe for most adults, more studies are needed to confirm its long-term safety. Unlike some sleep aids, melatonin supplements are not believed to be habit-forming, and they have relatively mild side effects. [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) National Library of Medicine, Biotech InformationThe National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information.[View Source](https://www.sleepfoundation.org/melatonin#references-253051)
###
- [Melatonin Side Effects](https://www.sleepfoundation.org/melatonin/melatonin-side-effects)
- [Can Melatonin Cause Nightmares?](https://www.sleepfoundation.org/melatonin/can-melatonin-cause-nightmares)
### Possible Interactions
Before you begin taking melatonin supplements, make sure to talk to your doctor about potential interactions that could compromise your health. Melatonin supplements have the potential to interact with medications and are generally not recommended for people who:
- Are pregnant or breastfeeding
- Have a bleeding disorder
- Experience depression
- Have seizures
- Are recipients of an organ transplant
Some medications—including [birth control pills](https://www.sleepfoundation.org/melatonin/effects-on-birth-control), certain serotonin reuptake inhibitors (SSRIs), and caffeine—might intensify the effects of melatonin supplements. Additionally, combining melatonin supplements with certain medications can reduce their effectiveness of the medications or produce unwanted side effects.
###
- [Does Melatonin Affect Birth Control?](https://www.sleepfoundation.org/melatonin/effects-on-birth-control)
- [What Happens if You Take Melatonin With Alcohol?](https://www.sleepfoundation.org/melatonin/melatonin-and-alcohol)
- [Can You Take Melatonin While Pregnant?](https://www.sleepfoundation.org/melatonin/pregnancy)
## How Much Melatonin Should I Take?
Over-the-counter supplements may contain as little as .2 milligrams or as much as 20 milligrams of melatonin. They also come in an array of formulations, including slow- and fast-release pills, [gummies](https://www.sleepfoundation.org/melatonin/best-melatonin-gummies), dissolvable tablets, liquids, gels, creams, and [patches](https://www.sleepfoundation.org/melatonin/melatonin-sleep-patch). Given the variety of available options, it’s important to talk to a doctor about the best choice for you.
The ideal [melatonin dosage](https://www.sleepfoundation.org/melatonin/melatonin-dosage-how-much-should-you-take) for you will depend on the sleep problem you’re treating, as well as your personal characteristics and health history. For adults and adolescents, doctors usually recommend dosages in the 1 to 5 milligram range. [Dosages for children](https://www.sleepfoundation.org/melatonin/melatonin-dosage-for-kids) may range from .2 milligrams to three milligrams.
“More is not better when it comes to melatonin. Going above 2-3 mg likely won’t work any better than 1mg or less, but does increase one’s risk for side effects.”

Dustin Cotliar, MD, MPH
Physician
Research indicates that melatonin dosages below 1 milligram may work just as well as higher doses. Unless directed otherwise by a doctor, it is best to start with the lowest possible dose and to increase as needed. Experts recommend taking no more than 10 milligrams per 24 hour period.
A complicating factor is the fact that many melatonin supplements are mislabeled. [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) National Library of Medicine, Biotech InformationThe National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information.[View Source](https://www.sleepfoundation.org/melatonin#references-79623) Recent studies have shown that the majority of melatonin products do not contain the advertised dosage of the sleep hormone. [Trusted Source](https://www.sleepfoundation.org/about-us/editorial-policy) JAMAJAMA, published continuously since 1883, is an international peer-reviewed general medical journal.[View Source](https://www.sleepfoundation.org/melatonin#references-253053) Tests have revealed that some products have significantly less melatonin than stated on the label, while others have [more than four times](https://www.sleepfoundation.org/melatonin/melatonin-overdose) the advertised amount of melatonin.
###
- [How Much Melatonin Should You Take](https://www.sleepfoundation.org/melatonin/melatonin-dosage-how-much-should-you-take)
- [Can You Overdose on Melatonin?](https://www.sleepfoundation.org/melatonin/melatonin-overdose)
## How to Choose Melatonin Supplements
In the United States, melatonin is considered a dietary supplement, so the Food and Drug Administration (FDA) does not subject it to the same rigorous standards as pharmaceutical drugs. For this reason, melatonin users should exercise caution when considering their melatonin options.
To give yourself the best chance of getting a [high quality product](https://www.sleepfoundation.org/sleep-aids/how-to-evaluate-sleep-supplements) with accurate dosage of melatonin, try looking for a U.S. Pharmacopeia certification on the label (which ensures that the product has been vetted by an outside organization), asking your doctor or a pharmacist to suggest a trusted brand, or picking a low-dose option.
###
- [Best Melatonin Supplements of 2026](https://www.sleepfoundation.org/melatonin/best-melatonin-supplements)
- [Best Melatonin Gummies of 2026](https://www.sleepfoundation.org/melatonin/best-melatonin-gummies)
- [Do Melatonin Sleep Patches Help You Fall Asleep?](https://www.sleepfoundation.org/melatonin/melatonin-sleep-patch)
- [Do Melatonin Gummies Work?](https://www.sleepfoundation.org/melatonin/do-melatonin-gummies-work)
### Alternatives to Melatonin
Melatonin isn’t the right choice for everyone. You may get the results you are looking for by cultivating healthy sleep habits, changing your sleeping environment, or addressing the root causes of your sleep difficulties.
- **Practice healthy sleep hygiene:** Committing to [healthy sleep practices](https://www.sleepfoundation.org/sleep-hygiene) can help you sleep better. Try going to bed and getting up at the same time every day. Develop a relaxing bedtime routine. Exercise regularly, and avoid caffeine and alcohol in the evening.
- **Avoid screens in the hours before bedtime:** Phones, tablets, TVs, and other electronic devices with screens emit [blue light](https://www.sleepfoundation.org/bedroom-environment/blue-light), which inhibits melatonin production.
- **Enhance your sleep environment:** Make sure that your bedroom is cool, dark, and quiet. Consider purchasing a more [comfortable mattress](https://www.sleepfoundation.org/best-mattress) or [high quality sheets](https://www.sleepfoundation.org/best-sheets).
- **Address underlying health concerns:** Many health problems can interfere with sleep. Treating conditions like chronic pain, [sleep apnea](https://www.sleepfoundation.org/sleep-apnea), and acid reflux may help you get better sleep.
- **Focus on your mental health:** Stress, anxiety, and depression can all make it hard to sleep. Consider seeing a counselor, engaging in [relaxation exercises](https://www.sleepfoundation.org/sleep-hygiene/relaxation-exercises-to-help-fall-asleep), or asking for support from family and friends.
- **Try cognitive behavioral therapy for insomnia (CBT-I):** If you have insomnia, you might try CBT-I, which is an [effective insomnia treatment](https://www.sleepfoundation.org/insomnia/treatment/cognitive-behavioral-therapy-insomnia). CBT-I involves addressing thought patterns and behaviors that interfere with sleep with the help of a licensed mental health professional.
Medical Disclaimer: The content on this page should not be taken as medical advice or used as a recommendation for any specific treatment or medication. Always consult your doctor before taking a new medication or changing your current treatment.

### Still have questions? Ask our community\!
Join our [Sleep Care Community](https://community.sleepfoundation.org/) — a trusted hub of sleep health professionals, product specialists, and people just like you. Whether you need expert sleep advice for your insomnia or you’re searching for the perfect mattress, we’ve got you covered. Get personalized guidance from the experts who know sleep best.
[About Our Editorial Team](https://www.sleepfoundation.org/about-us)

Written By
### Lucy Bryan, Contributing Writer
Lucy Bryan is a writer and editor with more than a decade of experience in higher education. She holds a B. A. in journalism from the University of North Carolina at Chapel Hill and an M.F.A. in creative writing from Penn State University.

Medically Reviewed by
### Dustin Cotliar, MD, MPH, Physician
Dustin Cotliar, MD, holds a medical degree from the State University of NY (SUNY) Downstate College of Medicine, and a master’s in public health from Columbia University, where he focused on healthcare policy and management. He is board-certified in Emergency Medicine, with over eight years of practice that includes emergency medicine, urgent care, and telemedicine.
[Learn more about our Editorial Team](https://www.sleepfoundation.org/about-us/who-we-are#team)
## References 9 Sources
1. Shane-McWhorter, L. (2023, January). Melatonin. Merck Manual Professional Version.
<https://www.merckmanuals.com/professional/special-subjects/dietary-supplements/melatonin>
2. Neubauer, D. (2024 February). Pharmacotherapy for insomnia in adults. In R. Benca, J. Elmore, & A. Eichler (Ed.). UpToDate.
<https://www.uptodate.com/contents/pharmacotherapy-for-insomnia-in-adults#H2582713949>
3. A.D.A.M. Medical Encyclopedia. (2023, October 18). Melatonin. MedlinePlus.
<https://medlineplus.gov/druginfo/natural/940.html>
4. Abbott, S. (2024, February). Non-24-hour sleep-wake rhythm disorder. In C. Goldstein & A. Eichler (Ed.). UpToDate.
<https://www.uptodate.com/contents/non-24-hour-sleep-wake-rhythm-disorder>
5. Auger, R. (2024, February). Delayed sleep-wake phase disorder. In C. Goldstein, R. Chervin, & A. Eichler (Ed.). UpToDate.
<https://www.uptodate.com/contents/delayed-sleep-wake-phase-disorder>
6. J. Owens. (2024, February). Pharmacotherapy for insomnia in children and adolescents: A rational approach. In R. Chervin & A. Eichler (Ed.). UpToDate.
<https://www.uptodate.com/contents/pharmacotherapy-for-insomnia-in-children-and-adolescents-a-rational-approach>
7. Salahub, C., Wu, P. E., Burry, L. D., Soong, C., Sheehan, K. A., MacMillan, T. E., & Lapointe-Shaw, L. (2022). Melatonin for Insomnia in Medical Inpatients: A Narrative Review. Journal of clinical medicine, 12(1), 256.
<https://pubmed.ncbi.nlm.nih.gov/36615056>
8. Erland, L. A., & Saxena, P. K. (2017). Melatonin natural health products and supplements: Presence of serotonin and significant variability of melatonin content. Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine, 13(2), 275–281.
<https://pubmed.ncbi.nlm.nih.gov/27855744/>
9. Cohen, P. A., Avula, B., Wang, Y. H., Katragunta, K., & Khan, I. (2023). Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US. JAMA, 329(16), 1401–1402.
<https://pubmed.ncbi.nlm.nih.gov/37097362/>
## Other Articles of Interest
### Sleep Medications
[Sleep Medications](https://www.sleepfoundation.org/sleep-aids/sleeping-pills) [How to Use Medications Safely](https://www.sleepfoundation.org/sleep-aids/how-to-use-sleep-medications-safely) [How Medications May Affect Sleep](https://www.sleepfoundation.org/sleep-aids/side-effects-of-sleeping-pills) [Over-the-Counter Sleep Aids](https://www.sleepfoundation.org/sleep-aids/over-the-counter-sleep-aids) [Compare Different Sleep Aids](https://www.sleepfoundation.org/sleep-aids/compare-sleep-medications)
### Sleep Deprivation
[Sleep Deprivation](https://www.sleepfoundation.org/sleep-deprivation) [Interrupted Sleep](https://www.sleepfoundation.org/sleep-deprivation/interrupted-sleep) [How Lack of Sleep Impacts Cognitive Performance](https://www.sleepfoundation.org/sleep-deprivation/lack-of-sleep-and-cognitive-impairment) [Lack of Sleep May Increase Calorie Consumption](https://www.sleepfoundation.org/sleep-deprivation/lack-sleep-may-increase-calorie-consumption) [REM Sleep Deprivation and Migraines](https://www.sleepfoundation.org/sleep-deprivation/sleep-deprivation-and-migraines)
### Bedroom Environment
[How to Create The Ideal Bedroom Environment](https://www.sleepfoundation.org/bedroom-environment) [Light and Sleep](https://www.sleepfoundation.org/bedroom-environment/light-and-sleep) [What Is White Noise?](https://www.sleepfoundation.org/noise-and-sleep/white-noise) [Technology In The Bedroom](https://www.sleepfoundation.org/bedroom-environment/technology-in-the-bedroom) [How Does Music Affect Sleep?](https://www.sleepfoundation.org/noise-and-sleep/music)
### Mattresses
[Best Mattresses](https://www.sleepfoundation.org/best-mattress) [Best Mattresses for Side Sleepers](https://www.sleepfoundation.org/best-mattress/best-mattress-for-side-sleepers) [Best Mattresses for Back Pain](https://www.sleepfoundation.org/best-mattress/best-mattress-for-back-pain) [Cooling Mattresses](https://www.sleepfoundation.org/best-mattress/best-cooling-mattress) [Hybrid Mattresses](https://www.sleepfoundation.org/best-mattress/best-hybrid-mattress)
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| Readable Markdown | [Skip to content](https://www.sleepfoundation.org/melatonin#post_content)
Key Takeaways
- Melatonin is a hormone that regulates the sleep-wake cycle.
- Supplementary melatonin can help you fall asleep or adjust to new time zones.
- Experts recommend a dosage of 1 to 5 milligrams of melatonin about 30 minutes before bed.
- Consult your doctor before taking melatonin or giving it to children.
Exogenous melatonin—a synthetic version of the body’s natural sleep hormone—has grown increasingly popular as a sleep aid over the last two decades. Nearly two thirds of American adults have taken melatonin supplements, and use among children and adolescents is also on the rise.
While scientific evidence suggests that [melatonin supplements](https://www.sleepfoundation.org/melatonin/best-melatonin-supplements) may help some people fall asleep more easily, this over-the-counter sleep aid is not a cure-all for sleep difficulties. Before using these supplements, it is important to understand how melatonin works, when it is most likely to be beneficial, and when to talk to your doctor.
Melatonin is a naturally occurring hormone that helps regulate the body’s [circadian rhyt](https://www.sleepfoundation.org/circadian-rhythm)[h](https://www.sleepfoundation.org/circadian-rhythm)[ms](https://www.sleepfoundation.org/circadian-rhythm), which are biological patterns that operate on a 24-hour clock. Specifically, melatonin plays a vital role in the sleep-wake cycle.
For a healthy individual with a normal sleep-wake cycle, the body begins producing melatonin every evening around the time sun goes down. This causes a gradual increase in sleepiness. Melatonin production continues into the night, peaking about seven hours after sunset. This helps the person stay asleep through the night. In the morning, melatonin drops to undetectable levels, as [exposure to light](https://www.sleepfoundation.org/bedroom-environment/light-and-sleep) inhibits production of the sleep hormone. This helps a person feel alert upon waking.

For some people who have difficulty falling asleep, taking supplemental melatonin about 30 minutes before bedtime may help. Supplementing naturally produced melatonin can reinforce circadian rhythms and signal to the body that it’s time to sleep. For this reason, melatonin supplements may be a good choice for individuals who:
- Have naturally low levels of melatonin
- Temporarily struggle to fall asleep due to circumstances such as [stress](https://www.sleepfoundation.org/insomnia/stress-and-insomnia) or [jet lag](https://www.sleepfoundation.org/travel-and-sleep/jet-lag)
- Take medications that interfere with sleep
- Are night owls but [need to wake early](https://www.sleepfoundation.org/sleep-faqs/how-to-become-a-morning-person)
- [How Melatonin Can Get You More Sleep](https://www.sleepfoundation.org/melatonin/melatonin-benefits)
### Melatonin for Sleep Disorders
Melatonin supplements are likely to benefit people with sleep disorders that affect their circadian rhythms. Supplemental melatonin may also benefit people with other types of sleep disorders, though results tend to be more variable and less impactful and prescription medications may be necessary.
- **Non-24-hour sleep-wake rhythm disorder (N24SWD):** People with [N24SWD](https://www.sleepfoundation.org/non-24-sleep-wake-disorder/symptoms-diagnosis), most of whom are blind, have circadian rhythms that do not synchronize with the 24-hour cycle of day and night. Taking melatonin an hour before bedtime can help align a person’s circadian clock with their environment, even in the absence of light and darkness.
- **Delayed sleep-wake phase disorder (DSWPD):** People with [DSWPD](https://www.sleepfoundation.org/delayed-sleep-wake-phase-syndrome), which mainly affects adolescents and young adults, aren’t able to fall asleep until long after conventional or desired bedtimes. While melatonin supplements aren’t a first-line treatment for DSWPD, they may help people with the disorder fall asleep earlier.
- **Insomnia:** Melatonin is not typically prescribed as the sole treatment for [insomnia](https://www.sleepfoundation.org/insomnia), but it may be used alongside other therapies to help reduce the amount of time it takes to fall asleep at bedtime.
- **Shift work disorder:** Small doses of melatonin may help [people who work rotating or night shifts](https://www.sleepfoundation.org/shift-work-disorder) fall asleep more easily during the day. However, some experts warn against taking melatonin for this purpose, as it can be difficult for shift workers to effectively time its administration or to predict its effect**s**.
## Say Goodbye to Insomnia
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### Melatonin for Kids
Research on the safety and efficacy of sleep aids for children is limited, so caregivers should not administer melatonin supplements to children unless a doctor has instructed them to do so.
Supplemental melatonin may be appropriate for children and adolescents with particular sleep, behavioral, and developmental disorders.
Melatonin supplements are rarely the right choice for children under the age of 5, whose sleep problems tend to be behavioral in nature and can often be resolved by establishing [healthy sleep habits](https://www.sleepfoundation.org/children-and-sleep/sleep-strategies-kids) and adjusting sleep environments. Additionally, melatonin should not be used to enhance sleep in children who don’t have sleep problems or to force them to go to bed earlier.
Accidental overdoses of melatonin supplements by children have been on the rise. It is vital that caregivers administer melatonin **according to instructions provided by a doctor** and safely store melatonin supplements out of the reach of children.
While research suggests that short-term use of melatonin is safe for most adults, more studies are needed to confirm its long-term safety. Unlike some sleep aids, melatonin supplements are not believed to be habit-forming, and they have relatively mild side effects.
### Possible Interactions
Before you begin taking melatonin supplements, make sure to talk to your doctor about potential interactions that could compromise your health. Melatonin supplements have the potential to interact with medications and are generally not recommended for people who:
- Are pregnant or breastfeeding
- Have a bleeding disorder
- Experience depression
- Have seizures
- Are recipients of an organ transplant
Some medications—including [birth control pills](https://www.sleepfoundation.org/melatonin/effects-on-birth-control), certain serotonin reuptake inhibitors (SSRIs), and caffeine—might intensify the effects of melatonin supplements. Additionally, combining melatonin supplements with certain medications can reduce their effectiveness of the medications or produce unwanted side effects.
Over-the-counter supplements may contain as little as .2 milligrams or as much as 20 milligrams of melatonin. They also come in an array of formulations, including slow- and fast-release pills, [gummies](https://www.sleepfoundation.org/melatonin/best-melatonin-gummies), dissolvable tablets, liquids, gels, creams, and [patches](https://www.sleepfoundation.org/melatonin/melatonin-sleep-patch). Given the variety of available options, it’s important to talk to a doctor about the best choice for you.
The ideal [melatonin dosage](https://www.sleepfoundation.org/melatonin/melatonin-dosage-how-much-should-you-take) for you will depend on the sleep problem you’re treating, as well as your personal characteristics and health history. For adults and adolescents, doctors usually recommend dosages in the 1 to 5 milligram range. [Dosages for children](https://www.sleepfoundation.org/melatonin/melatonin-dosage-for-kids) may range from .2 milligrams to three milligrams.
“More is not better when it comes to melatonin. Going above 2-3 mg likely won’t work any better than 1mg or less, but does increase one’s risk for side effects.”
Research indicates that melatonin dosages below 1 milligram may work just as well as higher doses. Unless directed otherwise by a doctor, it is best to start with the lowest possible dose and to increase as needed. Experts recommend taking no more than 10 milligrams per 24 hour period.
A complicating factor is the fact that many melatonin supplements are mislabeled. Recent studies have shown that the majority of melatonin products do not contain the advertised dosage of the sleep hormone. Tests have revealed that some products have significantly less melatonin than stated on the label, while others have [more than four times](https://www.sleepfoundation.org/melatonin/melatonin-overdose) the advertised amount of melatonin.
In the United States, melatonin is considered a dietary supplement, so the Food and Drug Administration (FDA) does not subject it to the same rigorous standards as pharmaceutical drugs. For this reason, melatonin users should exercise caution when considering their melatonin options.
To give yourself the best chance of getting a [high quality product](https://www.sleepfoundation.org/sleep-aids/how-to-evaluate-sleep-supplements) with accurate dosage of melatonin, try looking for a U.S. Pharmacopeia certification on the label (which ensures that the product has been vetted by an outside organization), asking your doctor or a pharmacist to suggest a trusted brand, or picking a low-dose option.
### Alternatives to Melatonin
Melatonin isn’t the right choice for everyone. You may get the results you are looking for by cultivating healthy sleep habits, changing your sleeping environment, or addressing the root causes of your sleep difficulties.
- **Practice healthy sleep hygiene:** Committing to [healthy sleep practices](https://www.sleepfoundation.org/sleep-hygiene) can help you sleep better. Try going to bed and getting up at the same time every day. Develop a relaxing bedtime routine. Exercise regularly, and avoid caffeine and alcohol in the evening.
- **Avoid screens in the hours before bedtime:** Phones, tablets, TVs, and other electronic devices with screens emit [blue light](https://www.sleepfoundation.org/bedroom-environment/blue-light), which inhibits melatonin production.
- **Enhance your sleep environment:** Make sure that your bedroom is cool, dark, and quiet. Consider purchasing a more [comfortable mattress](https://www.sleepfoundation.org/best-mattress) or [high quality sheets](https://www.sleepfoundation.org/best-sheets).
- **Address underlying health concerns:** Many health problems can interfere with sleep. Treating conditions like chronic pain, [sleep apnea](https://www.sleepfoundation.org/sleep-apnea), and acid reflux may help you get better sleep.
- **Focus on your mental health:** Stress, anxiety, and depression can all make it hard to sleep. Consider seeing a counselor, engaging in [relaxation exercises](https://www.sleepfoundation.org/sleep-hygiene/relaxation-exercises-to-help-fall-asleep), or asking for support from family and friends.
- **Try cognitive behavioral therapy for insomnia (CBT-I):** If you have insomnia, you might try CBT-I, which is an [effective insomnia treatment](https://www.sleepfoundation.org/insomnia/treatment/cognitive-behavioral-therapy-insomnia). CBT-I involves addressing thought patterns and behaviors that interfere with sleep with the help of a licensed mental health professional.
Medical Disclaimer: The content on this page should not be taken as medical advice or used as a recommendation for any specific treatment or medication. Always consult your doctor before taking a new medication or changing your current treatment.

### Still have questions? Ask our community\!
Join our [Sleep Care Community](https://community.sleepfoundation.org/) — a trusted hub of sleep health professionals, product specialists, and people just like you. Whether you need expert sleep advice for your insomnia or you’re searching for the perfect mattress, we’ve got you covered. Get personalized guidance from the experts who know sleep best.

Written By
### Lucy Bryan, Contributing Writer
Lucy Bryan is a writer and editor with more than a decade of experience in higher education. She holds a B. A. in journalism from the University of North Carolina at Chapel Hill and an M.F.A. in creative writing from Penn State University.

Medically Reviewed by
### Dustin Cotliar, MD, MPH, Physician
Dustin Cotliar, MD, holds a medical degree from the State University of NY (SUNY) Downstate College of Medicine, and a master’s in public health from Columbia University, where he focused on healthcare policy and management. He is board-certified in Emergency Medicine, with over eight years of practice that includes emergency medicine, urgent care, and telemedicine.
[Learn more about our Editorial Team](https://www.sleepfoundation.org/about-us/who-we-are#team)
## References 9 Sources
1. Shane-McWhorter, L. (2023, January). Melatonin. Merck Manual Professional Version.
<https://www.merckmanuals.com/professional/special-subjects/dietary-supplements/melatonin>
2. Neubauer, D. (2024 February). Pharmacotherapy for insomnia in adults. In R. Benca, J. Elmore, & A. Eichler (Ed.). UpToDate.
<https://www.uptodate.com/contents/pharmacotherapy-for-insomnia-in-adults#H2582713949>
3. A.D.A.M. Medical Encyclopedia. (2023, October 18). Melatonin. MedlinePlus.
<https://medlineplus.gov/druginfo/natural/940.html>
4. Abbott, S. (2024, February). Non-24-hour sleep-wake rhythm disorder. In C. Goldstein & A. Eichler (Ed.). UpToDate.
<https://www.uptodate.com/contents/non-24-hour-sleep-wake-rhythm-disorder>
5. Auger, R. (2024, February). Delayed sleep-wake phase disorder. In C. Goldstein, R. Chervin, & A. Eichler (Ed.). UpToDate.
<https://www.uptodate.com/contents/delayed-sleep-wake-phase-disorder>
6. J. Owens. (2024, February). Pharmacotherapy for insomnia in children and adolescents: A rational approach. In R. Chervin & A. Eichler (Ed.). UpToDate.
<https://www.uptodate.com/contents/pharmacotherapy-for-insomnia-in-children-and-adolescents-a-rational-approach>
7. Salahub, C., Wu, P. E., Burry, L. D., Soong, C., Sheehan, K. A., MacMillan, T. E., & Lapointe-Shaw, L. (2022). Melatonin for Insomnia in Medical Inpatients: A Narrative Review. Journal of clinical medicine, 12(1), 256.
<https://pubmed.ncbi.nlm.nih.gov/36615056>
8. Erland, L. A., & Saxena, P. K. (2017). Melatonin natural health products and supplements: Presence of serotonin and significant variability of melatonin content. Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine, 13(2), 275–281.
<https://pubmed.ncbi.nlm.nih.gov/27855744/>
9. Cohen, P. A., Avula, B., Wang, Y. H., Katragunta, K., & Khan, I. (2023). Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US. JAMA, 329(16), 1401–1402.
<https://pubmed.ncbi.nlm.nih.gov/37097362/> |
| Shard | 95 (laksa) |
| Root Hash | 1916647574837971495 |
| Unparsed URL | org,sleepfoundation!www,/melatonin s443 |