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Age cutoffPASSdownload_stamp > now() - 6 MONTH0.3 months ago
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URLhttps://www.nhs.uk/medicines/duloxetine/about-duloxetine/
Last Crawled2026-04-10 21:27:48 (9 days ago)
First Indexed2022-03-01 13:21:12 (4 years ago)
HTTP Status Code200
Meta TitleAbout duloxetine - NHS
Meta DescriptionNHS medicines information on duloxetine – what it's used for and key facts.
Meta Canonicalnull
Boilerpipe Text
Duloxetine is a type of antidepressant medicine known as a serotonin-noradrenaline reuptake inhibitor (SNRI). SNRIs are thought to work by increasing the amount of mood-enhancing chemicals, serotonin and noradrenaline, in your brain. It's used to treat depression and anxiety . It's also used to treat nerve pain, such as fibromyalgia , and can be used to treat stress urinary incontinence in women. Duloxetine comes as capsules. It is only available on prescription. Key facts Duloxetine usually takes 2 to 4 weeks to work. It may take longer if you're taking it for nerve pain. Common side effects include feeling sick, a dry mouth, headache, constipation and feeling sleepy. These side effects are usually mild and go away after a couple of weeks. If you and your doctor decide to take you off duloxetine, your doctor may recommend reducing your dose gradually to help prevent withdrawal symptoms. You may find you cannot concentrate properly while taking duloxetine. When you first start taking it, it's a good idea to stop driving and cycling, and avoid using machinery or tools, for the first few days until you know how this medicine makes you feel. Page last reviewed: 14 February 2022 Next review due: 14 February 2025
Markdown
 [Skip to main content](https://www.nhs.uk/medicines/duloxetine/about-duloxetine/#maincontent) - [Health A to Z](https://www.nhs.uk/health-a-to-z/) - [NHS services](https://www.nhs.uk/nhs-services/) - [Healthy living](https://www.nhs.uk/live-well/) - [Mental health](https://www.nhs.uk/mental-health/) - [Care and support](https://www.nhs.uk/social-care-and-support/) - [Home](https://www.nhs.uk/) - Browse More 1. [Home](https://www.nhs.uk/) 2. [Health A to Z](https://www.nhs.uk/health-a-to-z/) 3. [Medicines A to Z](https://www.nhs.uk/medicines/) 4. [Duloxetine](https://www.nhs.uk/medicines/duloxetine/) [Back to Duloxetine](https://www.nhs.uk/medicines/duloxetine/) # About duloxetine Duloxetine is a type of antidepressant medicine known as a serotonin-noradrenaline reuptake inhibitor (SNRI). SNRIs are thought to work by increasing the amount of mood-enhancing chemicals, serotonin and noradrenaline, in your brain. It's used to treat [depression](https://www.nhs.uk/mental-health/conditions/depression-in-adults/overview/) and [anxiety](https://www.nhs.uk/mental-health/conditions/generalised-anxiety-disorder/overview/). It's also used to treat nerve pain, such as [fibromyalgia](https://www.nhs.uk/conditions/fibromyalgia/), and can be used to treat stress [urinary incontinence](https://www.nhs.uk/conditions/urinary-incontinence/) in women. Duloxetine comes as capsules. It is only available on prescription. ## Key facts - Duloxetine usually takes 2 to 4 weeks to work. It may take longer if you're taking it for nerve pain. - Common side effects include feeling sick, a dry mouth, headache, constipation and feeling sleepy. These side effects are usually mild and go away after a couple of weeks. - If you and your doctor decide to take you off duloxetine, your doctor may recommend reducing your dose gradually to help prevent withdrawal symptoms. - You may find you cannot concentrate properly while taking duloxetine. When you first start taking it, it's a good idea to stop driving and cycling, and avoid using machinery or tools, for the first few days until you know how this medicine makes you feel. ## More in [Duloxetine](https://www.nhs.uk/medicines/duloxetine/) - About duloxetine - [Who can and cannot take it](https://www.nhs.uk/medicines/duloxetine/who-can-and-cannot-take-duloxetine/) - [How and when to take it](https://www.nhs.uk/medicines/duloxetine/how-and-when-to-take-duloxetine/) - [Side effects](https://www.nhs.uk/medicines/duloxetine/side-effects-of-duloxetine/) - [Pregnancy, breastfeeding and fertility](https://www.nhs.uk/medicines/duloxetine/pregnancy-breastfeeding-and-fertility-while-taking-duloxetine/) - [Taking duloxetine with other medicines and herbal supplements](https://www.nhs.uk/medicines/duloxetine/taking-duloxetine-with-other-medicines-and-herbal-supplements/) - [Common questions](https://www.nhs.uk/medicines/duloxetine/common-questions-about-duloxetine/) Page last reviewed: 14 February 2022 Next review due: 14 February 2025 ## Support links - [Home](https://www.nhs.uk/) - [Health A to Z](https://www.nhs.uk/health-a-to-z/) - [NHS services](https://www.nhs.uk/nhs-services/) - [Healthy living](https://www.nhs.uk/live-well/) - [Mental health](https://www.nhs.uk/mental-health/) - [Care and support](https://www.nhs.uk/social-care-and-support/) - [COVID-19](https://www.nhs.uk/conditions/covid-19/) - [NHS App](https://www.nhs.uk/nhs-app/) - [Find my NHS number](https://www.nhs.uk/nhs-services/online-services/find-nhs-number/) - [View your GP health record](https://www.nhs.uk/nhs-services/gps/view-your-gp-health-record/) - [View your test results](https://www.nhs.uk/nhs-services/online-services/view-your-test-results/) - [About the NHS](https://www.nhs.uk/using-the-nhs/about-the-nhs/) - [Healthcare abroad](https://www.nhs.uk/using-the-nhs/healthcare-abroad/) - [Other NHS websites](https://www.nhs.uk/nhs-sites/) - [Profile editor login](https://www.nhs.uk/our-policies/profile-editor-login/) - [About us](https://www.nhs.uk/about-us/) - [Report an issue with the NHS website](https://www.nhs.uk/report-an-issue-with-the-nhs-website) - [Accessibility statement](https://www.nhs.uk/accessibility-statement/) - [Our policies](https://www.nhs.uk/our-policies/) - [Cookies](https://www.nhs.uk/our-policies/choose-your-cookie-settings/) © Crown copyright
Readable Markdown
Duloxetine is a type of antidepressant medicine known as a serotonin-noradrenaline reuptake inhibitor (SNRI). SNRIs are thought to work by increasing the amount of mood-enhancing chemicals, serotonin and noradrenaline, in your brain. It's used to treat [depression](https://www.nhs.uk/mental-health/conditions/depression-in-adults/overview/) and [anxiety](https://www.nhs.uk/mental-health/conditions/generalised-anxiety-disorder/overview/). It's also used to treat nerve pain, such as [fibromyalgia](https://www.nhs.uk/conditions/fibromyalgia/), and can be used to treat stress [urinary incontinence](https://www.nhs.uk/conditions/urinary-incontinence/) in women. Duloxetine comes as capsules. It is only available on prescription. ## Key facts - Duloxetine usually takes 2 to 4 weeks to work. It may take longer if you're taking it for nerve pain. - Common side effects include feeling sick, a dry mouth, headache, constipation and feeling sleepy. These side effects are usually mild and go away after a couple of weeks. - If you and your doctor decide to take you off duloxetine, your doctor may recommend reducing your dose gradually to help prevent withdrawal symptoms. - You may find you cannot concentrate properly while taking duloxetine. When you first start taking it, it's a good idea to stop driving and cycling, and avoid using machinery or tools, for the first few days until you know how this medicine makes you feel. Page last reviewed: 14 February 2022 Next review due: 14 February 2025
Shard75 (laksa)
Root Hash11359509702434384875
Unparsed URLuk,nhs,www!/medicines/duloxetine/about-duloxetine/ s443