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URLhttps://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms/fatigue
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Meta TitleFatigue and Multiple Sclerosis | National MS Society
Meta DescriptionFatigue is a common and often debilitating symptom of multiple sclerosis. Learn more about the different types of fatigue with MS, fatigue management, and more.
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MS Fatigue: Often Misunderstood You may find that family members, friends, coworkers or employers don’t understand your fatigue. They may think you are depressed or just not trying hard enough. This is in part because it is hard to measure fatigue. Researchers are looking for a test to identify and measure fatigue. Investigators are recruiting for a new study to determine whether an online program can reduce fatigue by improving self-management. Types of Multiple Sclerosis Fatigue If you live with MS, you may experience different kinds of fatigue. For example, muscle spasms or bladder issues may keep you up at night. You may find that daily tasks such as getting dressed and preparing meals take more effort.  Depression  can also cause fatigue. Finally, you may experience “MS fatigue.” MS Fatigue Versus Regular Fatigue MS fatigue — referred to as “lassitude” — is unique to people with MS. It is different from other types of fatigue in that it: Generally occurs daily May occur in the morning, even after a restful night’s sleep Tends to get worse as the day progresses Tends to increase with heat and humidity Comes on easily and suddenly Is generally more severe than normal fatigue Is more likely to interfere with daily responsibilities Requires more recovery time Lasts longer MS-related fatigue does not appear to be directly related to either depression or your degree of physical impairment. Fatigue alone does not mean that you have MS. Other medical conditions and vitamin deficiencies, for example, can cause fatigue. It takes more than one symptom to diagnose MS . Still, if you are experiencing unusual levels of fatigue, talk to your healthcare provider about possible causes. To learn more about managing fatigue with MS, watch the video below. Find out more in the episode titled Fatigue and MS of Ask an MS Expert. Fatigue affects about 80% of people living with MS. If you are among them, learn strategies to manage it. Managing and Treating Fatigue
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... - [Home](https://www.nationalmssociety.org/ "National MS Society home") - [Understanding MS](https://www.nationalmssociety.org/understanding-ms) - [What Is Multiple Sclerosis?](https://www.nationalmssociety.org/understanding-ms/what-is-ms) - [Multiple Sclerosis Symptoms](https://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms) - Fatigue and Multiple Sclerosis ![A woman who lives with MS rests in a supported yoga pose.](https://cdn.sanity.io/images/y936aps5/production/05b3d20de8db8717301a3a8febf5ceffa1cc19da-1440x960.jpg) Gina Diagnosed in 2015 # Fatigue and Multiple Sclerosis About 80% of people with multiple sclerosis live with fatigue. Fatigue may be the most common symptom in people who otherwise have few activity limitations. Fatigue can interfere with your ability to function at home and work. We don't know what causes MS fatigue, but there are ways you can manage it. About 80% of people with multiple sclerosis live with fatigue. Fatigue may be the most common symptom in people who otherwise have few activity limitations. Fatigue can interfere with your ability to function at home and work. We don't know what causes MS fatigue, but there are ways you can manage it. ## MS Fatigue: Often Misunderstood You may find that family members, friends, coworkers or employers don’t understand your fatigue. They may think you are depressed or just not trying hard enough. This is in part because it is hard to measure fatigue. Researchers are looking for a test to identify and measure fatigue. Investigators are recruiting for [a new study](https://www.nationalmssociety.org/news-and-magazine/news/trial-alert-online-program-fatigue) to determine whether an online program can reduce fatigue by improving self-management. ### Types of Multiple Sclerosis Fatigue If you live with MS, you may experience different kinds of fatigue. For example, muscle spasms or bladder issues may keep you up at night. You may find that daily tasks such as getting dressed and preparing meals take more effort. [Depression](https://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms/depression) can also cause fatigue. Finally, you may experience “MS fatigue.” ### MS Fatigue Versus Regular Fatigue MS fatigue — referred to as “lassitude” — is unique to people with MS. It is different from other types of fatigue in that it: - Generally occurs daily - May occur in the morning, even after a restful night’s sleep - Tends to get worse as the day progresses - Tends to increase with heat and humidity - Comes on easily and suddenly - Is generally more severe than normal fatigue - Is more likely to interfere with daily responsibilities - Requires more recovery time - Lasts longer MS-related fatigue does not appear to be directly related to either depression or your degree of physical impairment.Fatigue alone does not mean that you have MS. Other medical conditions and vitamin deficiencies, for example, can cause fatigue. It takes more than one symptom to [diagnose MS](https://www.nationalmssociety.org/understanding-ms/what-is-ms/how-ms-is-diagnosed). Still, if you are experiencing unusual levels of fatigue, talk to your healthcare provider about possible causes. To learn more about managing fatigue with MS, watch the video below. Find out more in the episode titled [Fatigue and MS](https://www.youtube.com/watch?v=UiYbHogJmI4) of Ask an MS Expert. Fatigue affects about 80% of people living with MS. If you are among them, learn strategies to manage it. ### Impacts of Chronic Fatigue on Quality of Life Chronic fatigue can have a negative impact on many aspects of your life, including your mood, your ability to advocate for yourself, your relationships, your work and your interests. You may also experience [pain](https://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms/pain-itching) as an overlapping symptom with fatigue. These challenges may also impact your mental health. Talk to your healthcare team about ways to cope with fatigue directly and to maintain your quality of life. ### Impacts of Chronic Fatigue on Quality of Life Chronic fatigue can have a negative impact on many aspects of your life, including your mood, your ability to advocate for yourself, your relationships, your work and your interests. You may also experience [pain](https://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms/pain-itching) as an overlapping symptom with fatigue. These challenges may also impact your mental health. Talk to your healthcare team about ways to cope with fatigue directly and to maintain your quality of life. ## Managing and Treating Fatigue Consult your healthcare provider if fatigue becomes a problem and discuss a treatment plan. They can complete a comprehensive evaluation to identify factors adding to your fatigue and work with you to develop a treatment plan specific to your needs. ### Therapies To Decrease MS-Related Fatigue Different therapies, including [rehabilitation](https://www.nationalmssociety.org/for-professionals/for-healthcare-professionals/managing-and-treating-ms/rehabilitation-therapies/process), can help you plan ahead to prevent and reduce the effects of MS-related fatigue. They can teach you energy-saving strategies and help you avoid activities that trigger your fatigue.To address your fatigue, you might try: - Occupational therapy to simplify tasks at work and home and conserve energy - Physical therapy to learn energy-saving ways of walking (with or without assistive devices) and performing other daily tasks - Physical therapy to develop a regular exercise program to prevent deconditioning (muscle loss that occurs when you are less active) - Sleep regulation, which might involve treating other MS symptoms that interfere with sleep (e.g., spasticity, urinary dysfunction) - Psychological interventions, such as stress management, relaxation training, membership in a support group, cognitive behavioral therapy or psychotherapy - Heat management strategies to avoid overheating and to cool down To find therapists of any kind, use the [Find Doctors & Resources](https://www.nationalmssociety.org/resources/get-support/find-doctors-and-resources) tool. For additional support, contact an [MS Navigator](https://www.nationalmssociety.org/resources/get-support/ms-navigator). Consult your healthcare provider if fatigue becomes a problem and discuss a treatment plan. They can complete a comprehensive evaluation to identify factors adding to your fatigue and work with you to develop a treatment plan specific to your needs. ### Therapies To Decrease MS-Related Fatigue Different therapies, including [rehabilitation](https://www.nationalmssociety.org/for-professionals/for-healthcare-professionals/managing-and-treating-ms/rehabilitation-therapies/process), can help you plan ahead to prevent and reduce the effects of MS-related fatigue. They can teach you energy-saving strategies and help you avoid activities that trigger your fatigue.To address your fatigue, you might try: - Occupational therapy to simplify tasks at work and home and conserve energy - Physical therapy to learn energy-saving ways of walking (with or without assistive devices) and performing other daily tasks - Physical therapy to develop a regular exercise program to prevent deconditioning (muscle loss that occurs when you are less active) - Sleep regulation, which might involve treating other MS symptoms that interfere with sleep (e.g., spasticity, urinary dysfunction) - Psychological interventions, such as stress management, relaxation training, membership in a support group, cognitive behavioral therapy or psychotherapy - Heat management strategies to avoid overheating and to cool down To find therapists of any kind, use the [Find Doctors & Resources](https://www.nationalmssociety.org/resources/get-support/find-doctors-and-resources) tool. For additional support, contact an [MS Navigator](https://www.nationalmssociety.org/resources/get-support/ms-navigator). ### Medication and Nutrition for MS Fatigue No medications are specifically made for MS fatigue. But you and your healthcare provider may consider some for [off-label use](https://www.nationalmssociety.org/managing-ms/treating-ms/disease-modifying-therapies/off-label-use).You can also maximize your energy by eating healthfully. Experts agree on the following tips for a healthy diet: - Prepare meals at home as much as possible. - Incorporate colorful fresh fruits and vegetables daily. - If you choose to eat grains, choose whole grains over refined grains. - Avoid or limit processed foods and added sugars as much as possible. ### Medication and Nutrition for MS Fatigue No medications are specifically made for MS fatigue. But you and your healthcare provider may consider some for [off-label use](https://www.nationalmssociety.org/managing-ms/treating-ms/disease-modifying-therapies/off-label-use).You can also maximize your energy by eating healthfully. Experts agree on the following tips for a healthy diet: - Prepare meals at home as much as possible. - Incorporate colorful fresh fruits and vegetables daily. - If you choose to eat grains, choose whole grains over refined grains. - Avoid or limit processed foods and added sugars as much as possible. ![National Multiple Sclerosis Society Logo](https://www.nationalmssociety.org/webruntime/org-asset/7395f143c6/resource/081Pd0000000AHO/Ms-logo-Vertical.png) Quick Links - [Donate Now](https://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms/fatigue#open-donate-modal) - [Ways To Give](https://www.nationalmssociety.org/how-you-can-help/ways-to-give) - [Fundraising Events](https://www.nationalmssociety.org/how-you-can-help/get-involved/fundraising-events) - [Get Involved](https://www.nationalmssociety.org/how-you-can-help/get-involved) - [Contact Us](https://www.nationalmssociety.org/contact-us) - [Charitable Ratings](https://www.nationalmssociety.org/about-the-society/who-we-are/our-impact/charitable-ratings) - [Cookie Preferences]() ![Nmss Allyant Logo](https://www.nationalmssociety.org/webruntime/org-asset/7395f143c6/resource/081Pd0000003I5H) By using this website, you agree to our [Terms of Use](https://www.nationalmssociety.org/terms-of-use) (updated August 2025) and to our [Legal Notice and Privacy Policy](https://www.nationalmssociety.org/legal-notice-and-privacy-policy). You also agree that any donation complies with Florida SB 700. This bill prohibits donations from “foreign countries of concern.” See our [Donor Attestation Statement](https://www.nationalmssociety.org/donor-attestation-statement) for more details. © 2026 The National Multiple Sclerosis Society is a tax exempt 501(c)3 nonprofit organization. Its Identification Number (EIN) is 13-5661935. The National Multiple Sclerosis Society is proud to be a source of information on multiple sclerosis related topics. Unless otherwise indicated, the information provided is based on professional advice, published experience and expert opinion. However, the information does not constitute medical or legal advice. For specific medical advice, consult a qualified physician. For specific legal advice, consult a qualified attorney.
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MS Fatigue: Often Misunderstood You may find that family members, friends, coworkers or employers don’t understand your fatigue. They may think you are depressed or just not trying hard enough. This is in part because it is hard to measure fatigue. Researchers are looking for a test to identify and measure fatigue. Investigators are recruiting for [a new study](https://www.nationalmssociety.org/news-and-magazine/news/trial-alert-online-program-fatigue) to determine whether an online program can reduce fatigue by improving self-management. ### Types of Multiple Sclerosis Fatigue If you live with MS, you may experience different kinds of fatigue. For example, muscle spasms or bladder issues may keep you up at night. You may find that daily tasks such as getting dressed and preparing meals take more effort. [Depression](https://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms/depression) can also cause fatigue. Finally, you may experience “MS fatigue.” ### MS Fatigue Versus Regular Fatigue MS fatigue — referred to as “lassitude” — is unique to people with MS. It is different from other types of fatigue in that it: - Generally occurs daily - May occur in the morning, even after a restful night’s sleep - Tends to get worse as the day progresses - Tends to increase with heat and humidity - Comes on easily and suddenly - Is generally more severe than normal fatigue - Is more likely to interfere with daily responsibilities - Requires more recovery time - Lasts longer MS-related fatigue does not appear to be directly related to either depression or your degree of physical impairment.Fatigue alone does not mean that you have MS. Other medical conditions and vitamin deficiencies, for example, can cause fatigue. It takes more than one symptom to [diagnose MS](https://www.nationalmssociety.org/understanding-ms/what-is-ms/how-ms-is-diagnosed). Still, if you are experiencing unusual levels of fatigue, talk to your healthcare provider about possible causes.To learn more about managing fatigue with MS, watch the video below. Find out more in the episode titled [Fatigue and MS](https://www.youtube.com/watch?v=UiYbHogJmI4) of Ask an MS Expert. Fatigue affects about 80% of people living with MS. If you are among them, learn strategies to manage it. Managing and Treating Fatigue
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