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If you buy through links on this page, we may earn a small commission. [Here’s our process](https://www.medicalnewstoday.com/about/brand-and-product-vetting) # Melatonin for sleep: What to know  [Medically reviewed]() by [Dena Westphalen, PharmD]() — Written by Zawn Villines on May 15, 2019 - [What is melatonin?](https://www.medicalnewstoday.com/articles/325181#what-is-melatonin) - [How does it work?](https://www.medicalnewstoday.com/articles/325181#how-does-it-work) - [Dosage](https://www.medicalnewstoday.com/articles/325181#dosage) - [Side effects](https://www.medicalnewstoday.com/articles/325181#side-effects) - [Risks](https://www.medicalnewstoday.com/articles/325181#risks) - [For children](https://www.medicalnewstoday.com/articles/325181#for-children) - [Summary](https://www.medicalnewstoday.com/articles/325181#summary) Melatonin is a natural hormone that the brain releases in response to changes in light. It helps regulate the body’s internal clock, signaling that it is time to go to sleep. Melatonin supplements may help people sleep longer and fall asleep more quickly. Melatonin supplements may help with a wide range of sleep issues, including [insomnia](https://www.medicalnewstoday.com/articles/9155.php "Insomnia: Everything you need to know"), shift work sleep disorder, and sleep problems in children. In this article, learn more about melatonin for sleep, including its side effects, the right dosage, and how it works. ## [What is melatonin?]()  [Share on Pinterest](https://www.pinterest.com/pin/create/button/?url=https%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2F325181&media=https%3A%2F%2Fcdn-prod.medicalnewstoday.com%2Fcontent%2Fimages%2Farticles%2F325%2F325181%2Fperson-holding-a-melatonin-pill-for-sleep.jpg&description=Melatonin%20for%20sleep%3A%20Dosage%2C%20side%20effects%2C%20and%20how%20it%20works "Share on Pinterest") Melatonin supplements may improve sleep. Melatonin is a hormone that tells the body that it is time to sleep. In people who do not have problems sleeping, the body follows an internal clock of roughly 24 hours called a circadian rhythm. Changes in light and temperature help tell the body when to feel tired. The brain releases melatonin when it is dark, suggesting that melatonin helps regulate sleepiness in these conditions. Exposure to light may block the production of melatonin, which is why it is important to sleep in a dark room. A [2015 study](https://www.sciencedirect.com/science/article/pii/S0896627315001312) examined zebrafish with a rare mutation that stopped them from producing melatonin. These fish slept very little, even when researchers ensured that they had adequate exposure to darkness. These findings suggest that the body depends on melatonin, not just changes in light, to help it get to sleep. ## [How does it work?]() Melatonin supplements may improve sleep by boosting melatonin levels in people whose bodies do not produce enough of this hormone. These supplements may also improve sleep in people who produce enough melatonin but still struggle to sleep for other reasons. Melatonin changes how the body responds to darkness, helping it enter a rhythm of nighttime drowsiness. Exposure to light at night — including light from computer and television screens — may suppress the body’s natural melatonin production and disrupt sleep. Likewise, people who sleep during the day because they work at night may not produce melatonin when it is time to sleep. Melatonin supplements can help counteract this effect. Research consistently shows that melatonin can help people sleep longer and fall asleep more quickly. A [2013 meta-analysis](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063773%20) that included 1,683 study participants found that melatonin decreased the amount of time that it took the participants to fall asleep compared with a [placebo](https://www.medicalnewstoday.com/articles/306437.php "Is the placebo effect real?"). It also increased the duration of their sleep. [Other research](https://nccih.nih.gov/health/melatonin) has suggested that melatonin can improve sleep in people with: - [jet lag](https://www.medicalnewstoday.com/articles/165339.php "Jet lag: What it is and how to beat it") - shift work sleep disorder - delayed sleep phase disorder - sleep disorders relating to blindness - [sleep issues](https://www.sciencedirect.com/science/article/pii/S0022510X11006551) due to low melatonin in people with [multiple sclerosis](https://www.medicalnewstoday.com/articles/37556.php "Multiple sclerosis: What you need to know") (MS) - [sleep difficulties](https://pediatrics.aappublications.org/content/134/2/e397.abstract) in children with atopic dermatitis ### Resources for healthy sleep To discover more evidence-based information and resources on the science of healthy sleep, visit [our dedicated hub](https://www.medicalnewstoday.com/sleep). ## [Dosage]() The ideal dosage for melatonin varies from person to person. Various factors, such as [body weight](https://www.medicalnewstoday.com/info/obesity/how-much-should-i-weigh.php "How Much Should I Weigh?"), metabolism, and overall health, may also influence the way that the body responds to melatonin. A typical dose of melatonin is between [1 mg and 5 mg](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405617/). It is best to take this about an hour before bed. People can try starting with a low dose and looking for any adverse side effects. They can then gradually increase the dose until their sleep improves, if necessary. It is important not to take more than 5 mg unless a doctor recommends a higher dose. ## [Side effects]() One of the [most common](https://nccih.nih.gov/health/melatonin) side effects of melatonin is drowsiness. Some people may notice that they feel sleepy or groggy the morning after taking melatonin. Taking melatonin earlier in the evening or reducing the dose may help a person wake up feeling refreshed. Other possible side effects include: - [headaches](https://www.medicalnewstoday.com/articles/73936.php "What is causing this headache?") - dizziness - nausea In some people with [dementia](https://www.medicalnewstoday.com/articles/142214.php "Dementia: Symptoms, stages, and types"), melatonin [may trigger a bad mood](https://nccih.nih.gov/health/melatonin). Although melatonin is a natural chemical, it is important to treat it the same as any other medication. It is possible for melatonin to interact harmfully with other drugs by reducing their effectiveness, triggering negative side effects, or changing the way that the body metabolizes the drug. People who take other medications should talk to a doctor before trying melatonin. As with any medication, an allergic reaction is possible. People with a history of allergic reactions to supplements should avoid melatonin. Anyone who notices signs of an allergic reaction, such as itching or [hives](https://www.medicalnewstoday.com/articles/157260.php "What are hives (urticaria)?"), should contact a doctor. If a person has trouble breathing or feels as though they are choking, they should go to the emergency room or call 911. ## [Risks]() [Very limited data](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830653/) suggest that melatonin might increase the risk of seizures, but other studies have found that it may actually lower this risk. People with seizure disorders or a family history of seizures should consult a doctor before trying melatonin. Some research involving children also [suggests](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830653/) that melatonin could alter the function of the hypothalamic-pituitary-gonadal axis. In turn, this could change how the body produces or metabolizes hormones, potentially affecting the child’s growth. However, this research is inconclusive. ## [For children]() [Share on Pinterest](https://www.pinterest.com/pin/create/button/?url=https%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2F325181&media=https%3A%2F%2Fcdn-prod.medicalnewstoday.com%2Fcontent%2Fimages%2Farticles%2F325%2F325181%2Fdoctor-speaking-with-patient-and-child.jpg&description=Melatonin%20for%20sleep%3A%20Dosage%2C%20side%20effects%2C%20and%20how%20it%20works "Share on Pinterest") A person should speak to a doctor before giving melatonin to children. [Short-term studies](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830653/) of melatonin in children show that it is safe, including in [children with autism](https://link.springer.com/article/10.1007/s10803-011-1418-3). Before trying melatonin, parents and caregivers should help a child adopt good sleep practices, such as: - maintaining a regular, predictable sleep routine - scheduling dinner at least 2 hours before bedtime - avoiding caffeine and other stimulant drugs - keeping the sleep environment quiet, dark, and cool - not using screens for at least an hour before bedtime Choosing the right melatonin dosage for children can be challenging as the drug is a supplement with no approved dosing guidelines. When in doubt, it is best to consult a doctor. The authors of [a paper](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380753/) on the use of melatonin in Canada noted that typical doses were 0.75 mg to 1 mg in children younger than 6 years, 1.5 mg to 3 mg in older children, and 5 mg to 10 mg in adolescents. It is best for children to take it between 30 and 60 minutes before bedtime. They also stated that there was no evidence to support the use of melatonin in children younger than 2 years. A small [2011 study](https://link.springer.com/article/10.1007/s10803-011-1418-3) of children with [autism](https://www.medicalnewstoday.com/info/autism/ "What is Autism?") found that a lower dose could be effective. Just 1 mg or 3 mg of melatonin was beneficial for most children in the study. Although there is no reason to suspect that melatonin might cause long-term harm, [no research has established](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830653/) that it is safe to use for extended periods. For this reason, parents and caregivers should use melatonin for the shortest possible period and consult a doctor before giving their child melatonin or any other supplement. ## [Summary]() Sleep difficulties are common. While some people only experience occasional sleeplessness, others deal with chronic sleep problems. Melatonin offers a natural solution that mimics the hormone that the brain already produces. For many people, melatonin is an effective alternative to prescription medications for sleep. However, people should treat melatonin the same as any other medication and carefully watch for side effects. Melatonin supplements for sleep are available in pharmacies, some natural health stores, and [online](https://www.amazon.com/s?k=melatonin&tag=healthline-subtag-20&ascsubtag=null&correlationId=null). - [Endocrinology](https://www.medicalnewstoday.com/categories/endocrinology) - [Pharmacy / Pharmacist](https://www.medicalnewstoday.com/categories/pharmacy) - [Sleep / Sleep Disorders / Insomnia](https://www.medicalnewstoday.com/categories/sleep) - [Complementary Medicine / Alternative Medicine](https://www.medicalnewstoday.com/categories/complementary_medicine) - [Cat 1](https://www.medicalnewstoday.com/categories/cat1) - [sleepsupplements](https://www.medicalnewstoday.com/cat1/cat1-sleepsupplements) ### How we reviewed this article: Sources Medical News Today has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our [editorial policy](https://www.medicalnewstoday.com/articles/process). - Chang, Y.-S. *et al.* (2014). Atopic dermatitis, melatonin, and sleep disturbance \[Abstract\]. <https://pediatrics.aappublications.org/content/134/2/e397.abstract> - Cummings, C. (2012). Melatonin for the management of sleep disorders in children and adolescents. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380753/> - Ferracioli-Oda, E., *et al.* (2013). Meta-analysis: Melatonin for the treatment of primary sleep disorders. [https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063773%20](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063773%20) - Gandhi, A. V., *et al.* (2015). Melatonin is required for the circadian regulation of sleep. <https://www.sciencedirect.com/science/article/pii/S0896627315001312> - How much melatonin should you really be taking? (n.d.). <https://www.sleep.org/articles/how-much-melatonin-to-take/> - Janjua, I., & Goldman, R. D. (2016). Sleep-related melatonin use in healthy children. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830653/> - Malow, B., *et al.* (2012). Melatonin for sleep in children with autism: A controlled trial examining dose, tolerability, and outcomes \[Abstract\]. <https://link.springer.com/article/10.1007/s10803-011-1418-3> - Melamud, L., *et al.* (2012). Melatonin dysregulation, sleep disturbances and fatigue in multiple sclerosis. <https://www.sciencedirect.com/science/article/pii/S0022510X11006551> - Melatonin: In depth. (2018). <https://nccih.nih.gov/health/melatonin> - Tordjman. S., et al. (2017, April). Melatonin: Pharmacology, functions and therapeutic benefits. *Current Neuropharmacol.* Retrieved from <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405617/> Share this article  [Medically reviewed]() by [Dena Westphalen, PharmD]() — Written by Zawn Villines on May 15, 2019 ## Latest news - [Two days of oatmeal may help reduce 'bad' cholesterol levels, study finds](https://www.medicalnewstoday.com/articles/two-days-oatmeal-reduce-ldl-cholesterol-levels-study) - [Is sleep the missing piece in mental health?](https://www.medicalnewstoday.com/articles/is-sleep-the-missing-piece-in-mental-health) - [Is this why dementia affects more women? 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Learn more about how long it lasts.](https://www.medicalnewstoday.com/articles/how-long-does-melatonin-last?utm_source=ReadNext) [READ MORE](https://www.medicalnewstoday.com/articles/how-long-does-melatonin-last?utm_source=ReadNext) - [What to know about natural melatonin](https://www.medicalnewstoday.com/articles/natural-melatonin?utm_source=ReadNext) Medically reviewed by [Deborah Weatherspoon, Ph.D., MSN](https://www.medicalnewstoday.com/reviewers) [Natural melatonin is a hormone which helps regulate the sleep-wake cycle. 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Melatonin is a natural hormone that the brain releases in response to changes in light. It helps regulate the body’s internal clock, signaling that it is time to go to sleep. Melatonin supplements may help people sleep longer and fall asleep more quickly. Melatonin supplements may help with a wide range of sleep issues, including [insomnia](https://www.medicalnewstoday.com/articles/9155.php "Insomnia: Everything you need to know"), shift work sleep disorder, and sleep problems in children. In this article, learn more about melatonin for sleep, including its side effects, the right dosage, and how it works. Melatonin is a hormone that tells the body that it is time to sleep. In people who do not have problems sleeping, the body follows an internal clock of roughly 24 hours called a circadian rhythm. Changes in light and temperature help tell the body when to feel tired. The brain releases melatonin when it is dark, suggesting that melatonin helps regulate sleepiness in these conditions. Exposure to light may block the production of melatonin, which is why it is important to sleep in a dark room. A [2015 study](https://www.sciencedirect.com/science/article/pii/S0896627315001312) examined zebrafish with a rare mutation that stopped them from producing melatonin. These fish slept very little, even when researchers ensured that they had adequate exposure to darkness. These findings suggest that the body depends on melatonin, not just changes in light, to help it get to sleep. Melatonin supplements may improve sleep by boosting melatonin levels in people whose bodies do not produce enough of this hormone. These supplements may also improve sleep in people who produce enough melatonin but still struggle to sleep for other reasons. Melatonin changes how the body responds to darkness, helping it enter a rhythm of nighttime drowsiness. Exposure to light at night — including light from computer and television screens — may suppress the body’s natural melatonin production and disrupt sleep. Likewise, people who sleep during the day because they work at night may not produce melatonin when it is time to sleep. Melatonin supplements can help counteract this effect. Research consistently shows that melatonin can help people sleep longer and fall asleep more quickly. A [2013 meta-analysis](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063773%20) that included 1,683 study participants found that melatonin decreased the amount of time that it took the participants to fall asleep compared with a [placebo](https://www.medicalnewstoday.com/articles/306437.php "Is the placebo effect real?"). It also increased the duration of their sleep. [Other research](https://nccih.nih.gov/health/melatonin) has suggested that melatonin can improve sleep in people with: - [jet lag](https://www.medicalnewstoday.com/articles/165339.php "Jet lag: What it is and how to beat it") - shift work sleep disorder - delayed sleep phase disorder - sleep disorders relating to blindness - [sleep issues](https://www.sciencedirect.com/science/article/pii/S0022510X11006551) due to low melatonin in people with [multiple sclerosis](https://www.medicalnewstoday.com/articles/37556.php "Multiple sclerosis: What you need to know") (MS) - [sleep difficulties](https://pediatrics.aappublications.org/content/134/2/e397.abstract) in children with atopic dermatitis The ideal dosage for melatonin varies from person to person. Various factors, such as [body weight](https://www.medicalnewstoday.com/info/obesity/how-much-should-i-weigh.php "How Much Should I Weigh?"), metabolism, and overall health, may also influence the way that the body responds to melatonin. A typical dose of melatonin is between [1 mg and 5 mg](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405617/). It is best to take this about an hour before bed. People can try starting with a low dose and looking for any adverse side effects. They can then gradually increase the dose until their sleep improves, if necessary. It is important not to take more than 5 mg unless a doctor recommends a higher dose. One of the [most common](https://nccih.nih.gov/health/melatonin) side effects of melatonin is drowsiness. Some people may notice that they feel sleepy or groggy the morning after taking melatonin. Taking melatonin earlier in the evening or reducing the dose may help a person wake up feeling refreshed. Other possible side effects include: - [headaches](https://www.medicalnewstoday.com/articles/73936.php "What is causing this headache?") - dizziness - nausea Although melatonin is a natural chemical, it is important to treat it the same as any other medication. It is possible for melatonin to interact harmfully with other drugs by reducing their effectiveness, triggering negative side effects, or changing the way that the body metabolizes the drug. People who take other medications should talk to a doctor before trying melatonin. As with any medication, an allergic reaction is possible. People with a history of allergic reactions to supplements should avoid melatonin. Anyone who notices signs of an allergic reaction, such as itching or [hives](https://www.medicalnewstoday.com/articles/157260.php "What are hives (urticaria)?"), should contact a doctor. If a person has trouble breathing or feels as though they are choking, they should go to the emergency room or call 911. [Very limited data](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830653/) suggest that melatonin might increase the risk of seizures, but other studies have found that it may actually lower this risk. People with seizure disorders or a family history of seizures should consult a doctor before trying melatonin. Some research involving children also [suggests](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830653/) that melatonin could alter the function of the hypothalamic-pituitary-gonadal axis. In turn, this could change how the body produces or metabolizes hormones, potentially affecting the child’s growth. However, this research is inconclusive. Before trying melatonin, parents and caregivers should help a child adopt good sleep practices, such as: - maintaining a regular, predictable sleep routine - scheduling dinner at least 2 hours before bedtime - avoiding caffeine and other stimulant drugs - keeping the sleep environment quiet, dark, and cool - not using screens for at least an hour before bedtime Choosing the right melatonin dosage for children can be challenging as the drug is a supplement with no approved dosing guidelines. When in doubt, it is best to consult a doctor. The authors of [a paper](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380753/) on the use of melatonin in Canada noted that typical doses were 0.75 mg to 1 mg in children younger than 6 years, 1.5 mg to 3 mg in older children, and 5 mg to 10 mg in adolescents. It is best for children to take it between 30 and 60 minutes before bedtime. They also stated that there was no evidence to support the use of melatonin in children younger than 2 years. A small [2011 study](https://link.springer.com/article/10.1007/s10803-011-1418-3) of children with [autism](https://www.medicalnewstoday.com/info/autism/ "What is Autism?") found that a lower dose could be effective. Just 1 mg or 3 mg of melatonin was beneficial for most children in the study. Although there is no reason to suspect that melatonin might cause long-term harm, [no research has established](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830653/) that it is safe to use for extended periods. For this reason, parents and caregivers should use melatonin for the shortest possible period and consult a doctor before giving their child melatonin or any other supplement. Sleep difficulties are common. While some people only experience occasional sleeplessness, others deal with chronic sleep problems. Melatonin offers a natural solution that mimics the hormone that the brain already produces. For many people, melatonin is an effective alternative to prescription medications for sleep. However, people should treat melatonin the same as any other medication and carefully watch for side effects. Melatonin supplements for sleep are available in pharmacies, some natural health stores, and [online](https://www.amazon.com/s?k=melatonin&tag=healthline-subtag-20&ascsubtag=null&correlationId=null).