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URLhttps://www.mayoclinic.org/symptoms/loss-of-smell/basics/causes/sym-20050804
Last Crawled2026-04-01 05:03:14 (22 days ago)
First Indexed2016-10-03 19:52:13 (9 years ago)
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Meta TitleLoss of smell (anosmia) Causes - Mayo Clinic
Meta DescriptionA stuffy nose is one cause of this symptom. Learn about other causes and when it might be serious.
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A stuffy nose from a cold is a common cause for a partial, brief loss of smell. A polyp or swelling inside the nose can lead to a loss of smell. Aging can cause a loss of smell, especially after age 60. What is smell? The nose and an area in the upper throat have special cells, called receptors, that discern odors. These receptors send a message to the brain about each smell. The brain then figures out what the smell is. Any problem along the way can affect the sense of smell. Problems can include a stuffy nose; something that blocks the nose; swelling, called inflammation; nerve damage; or an issue with how the brain works. Problems with the inner lining of the nose Conditions that cause congestion or other issues inside the nose may include: Acute sinusitis Chronic sinusitis Common cold Coronavirus disease 2019 (COVID-19) Hay fever Influenza (flu) Nonallergic rhinitis Smoking Blockages in the inside of the nose, called the nasal passages Conditions that block the flow of air through the nose can include: Nasal polyps Tumors Damage to your brain or nerves The following can cause damage to the nerves to the area of the brain that picks up smells or to the brain itself to: Aging Alzheimer's disease Being around toxic chemicals, such as those used in solvents Brain aneurysm Brain surgery Brain tumor Diabetes Huntington's disease Hypothyroidism (underactive thyroid) Kallmann's syndrome (a rare genetic condition) Korsakoff's psychosis, a brain condition caused by the lack of vitamin B-1, also called thiamin Lewy body dementia Medicines, such as some for high blood pressure, some antibiotics and antihistamines, and some nasal sprays Multiple sclerosis Parkinson's disease Poor nutrition, such as too little zinc or vitamin B-12 in the diet Pseudotumor cerebri (idiopathic intracranial hypertension) Radiation therapy Rhinoplasty Traumatic brain injury Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis. From Mayo Clinic to your inbox Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview. Email We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices . You may opt out of email communications at any time by clicking on the unsubscribe link in the email. Share Tweet Dec. 24, 2025 Ferri FF. T-differential diagnosis. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 6, 2023. Smell disorders. National Institute on Deafness and Other Communication Disorders. https://www.nidcd.nih.gov/health/smell-disorders. Accessed April 6, 2023. Lalwani AK. Olfactory dysfunction. In: Current Diagnosis & Treatment in Otolaryngology — Head & Neck Surgery. 4th ed. McGraw Hill; 2020. https://accessmedicine.mhmedical.com. Accessed April 6, 2023. Lafreniere D. Taste and olfactory disorders in adults: Anatomy and etiology. https://www.uptodate.com/contents/search. Accessed April 7, 2023. Anosmia. Merck Manual Professional Version. https://www.merckmanuals.com/professional/ear,-nose,-and-throat-disorders/approach-to-the-patient-with-nasal-and-pharyngeal-symptoms/anosmia. Accessed April 6, 2023. See also Bardet-Biedl syndrome (BBS) Chronic sinusitis Coronavirus disease 2019 (COVID-19) Coronavirus infection by race COVID-19 and pets COVID-19 and vitamin D COVID-19 and your mental health COVID-19 drugs: Are there any that work? COVID-19 in babies and children COVID-19 travel advice COVID-19 vaccines for kids: What you need to know COVID-19 vaccines: Get the facts COVID-19 variants COVID-19 vs. flu: Similarities and differences COVID-19, cold, allergies and the flu: What are the differences? COVID-19: How can I protect myself? COVID-19: Who's at higher risk of serious symptoms? Debunking COVID-19 myths Different types of COVID-19 vaccines: How they work Fight coronavirus (COVID-19) transmission at home Herd immunity and COVID-19: What you need to know How do COVID-19 antibody tests differ from diagnostic tests? How well do face masks protect against COVID-19? Is hydroxychloroquine a treatment for COVID-19? Long COVID: Lasting effects of COVID-19 Loss of taste and smell Mayo Clinic Minute: How dirty are common surfaces? Mayo Clinic Minute: You're washing your hands all wrong Nasal polyps Pregnancy and COVID-19: What are the risks? Safe outdoor activities during the COVID-19 pandemic Safety tips for attending school during COVID-19 Sex and COVID-19 Skull base tumors Treating COVID-19 at home: Care tips for you and others Unusual symptoms of coronavirus .
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A stuffy nose from a cold is a common cause for a partial, brief loss of smell. A polyp or swelling inside the nose can lead to a loss of smell. Aging can cause a loss of smell, especially after age 60. ### What is smell? The nose and an area in the upper throat have special cells, called receptors, that discern odors. These receptors send a message to the brain about each smell. The brain then figures out what the smell is. Any problem along the way can affect the sense of smell. Problems can include a stuffy nose; something that blocks the nose; swelling, called inflammation; nerve damage; or an issue with how the brain works. ### Problems with the inner lining of the nose Conditions that cause congestion or other issues inside the nose may include: 1. [Acute sinusitis](https://www.mayoclinic.org/diseases-conditions/acute-sinusitis/symptoms-causes/syc-20351671) 2. [Chronic sinusitis](https://www.mayoclinic.org/diseases-conditions/chronic-sinusitis/symptoms-causes/syc-20351661) 3. [Common cold](https://www.mayoclinic.org/diseases-conditions/common-cold/symptoms-causes/syc-20351605) 4. [Coronavirus disease 2019 (COVID-19)](https://www.mayoclinic.org/diseases-conditions/coronavirus/symptoms-causes/syc-20479963) 5. [Hay fever](https://www.mayoclinic.org/diseases-conditions/hay-fever/symptoms-causes/syc-20373039) 6. [Influenza (flu)](https://www.mayoclinic.org/diseases-conditions/flu/symptoms-causes/syc-20351719) 7. [Nonallergic rhinitis](https://www.mayoclinic.org/diseases-conditions/nonallergic-rhinitis/symptoms-causes/syc-20351229) 8. Smoking ### Blockages in the inside of the nose, called the nasal passages Conditions that block the flow of air through the nose can include: 1. [Nasal polyps](https://www.mayoclinic.org/diseases-conditions/nasal-polyps/symptoms-causes/syc-20351888) 2. Tumors ### Damage to your brain or nerves The following can cause damage to the nerves to the area of the brain that picks up smells or to the brain itself to: 1. Aging 2. [Alzheimer's disease](https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/symptoms-causes/syc-20350447) 3. Being around toxic chemicals, such as those used in solvents 4. [Brain aneurysm](https://www.mayoclinic.org/diseases-conditions/brain-aneurysm/symptoms-causes/syc-20361483) 5. Brain surgery 6. [Brain tumor](https://www.mayoclinic.org/diseases-conditions/brain-tumor/symptoms-causes/syc-20350084) 7. [Diabetes](https://www.mayoclinic.org/diseases-conditions/diabetes/symptoms-causes/syc-20371444) 8. [Huntington's disease](https://www.mayoclinic.org/diseases-conditions/huntingtons-disease/symptoms-causes/syc-20356117) 9. [Hypothyroidism (underactive thyroid)](https://www.mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-20350284) 10. Kallmann's syndrome (a rare genetic condition) 11. Korsakoff's psychosis, a brain condition caused by the lack of vitamin B-1, also called thiamin 12. [Lewy body dementia](https://www.mayoclinic.org/diseases-conditions/lewy-body-dementia/symptoms-causes/syc-20352025) 13. Medicines, such as some for high blood pressure, some antibiotics and antihistamines, and some nasal sprays 14. [Multiple sclerosis](https://www.mayoclinic.org/diseases-conditions/multiple-sclerosis/symptoms-causes/syc-20350269) 15. [Parkinson's disease](https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055) 16. Poor nutrition, such as too little zinc or vitamin B-12 in the diet 17. [Pseudotumor cerebri (idiopathic intracranial hypertension)](https://www.mayoclinic.org/diseases-conditions/pseudotumor-cerebri/symptoms-causes/syc-20354031) 18. [Radiation therapy](https://www.mayoclinic.org/tests-procedures/radiation-therapy/about/pac-20385162) 19. [Rhinoplasty](https://www.mayoclinic.org/tests-procedures/rhinoplasty/about/pac-20384532) 20. [Traumatic brain injury](https://www.mayoclinic.org/diseases-conditions/traumatic-brain-injury/symptoms-causes/syc-20378557) Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis. ## From Mayo Clinic to your inbox Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. [Click here for an email preview.](https://links.e.response.mayoclinic.org/EmailPreview-GeneralHealth) Email We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our [Notice of Privacy Practices](https://mcforms.mayo.edu/mc5200-mc5299/mc5256-01.pdf). You may opt out of email communications at any time by clicking on the unsubscribe link in the email. - [Share](https://www.facebook.com/sharer.php?u=https://www.mayoclinic.org/symptoms/loss-of-smell/basics/causes/sym-20050804) - [Tweet](http://twitter.com/intent/tweet?url=https://www.mayoclinic.org/symptoms/loss-of-smell/basics/causes/sym-20050804&text=Loss+of+smell+\(anosmia\)+Causes) Dec. 24, 2025 1. Ferri FF. T-differential diagnosis. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 6, 2023. 2. Smell disorders. National Institute on Deafness and Other Communication Disorders. https://www.nidcd.nih.gov/health/smell-disorders. Accessed April 6, 2023. 3. Lalwani AK. Olfactory dysfunction. In: Current Diagnosis & Treatment in Otolaryngology — Head & Neck Surgery. 4th ed. McGraw Hill; 2020. https://accessmedicine.mhmedical.com. Accessed April 6, 2023. 4. Lafreniere D. Taste and olfactory disorders in adults: Anatomy and etiology. https://www.uptodate.com/contents/search. Accessed April 7, 2023. 5. Anosmia. Merck Manual Professional Version. https://www.merckmanuals.com/professional/ear,-nose,-and-throat-disorders/approach-to-the-patient-with-nasal-and-pharyngeal-symptoms/anosmia. Accessed April 6, 2023. ## See also 1. [Bardet-Biedl syndrome (BBS)](https://www.mayoclinic.org/diseases-conditions/bardet-biedl-syndrome/symptoms-causes/syc-20586227) 2. [Chronic sinusitis](https://www.mayoclinic.org/diseases-conditions/chronic-sinusitis/symptoms-causes/syc-20351661) 3. [Coronavirus disease 2019 (COVID-19)](https://www.mayoclinic.org/diseases-conditions/coronavirus/symptoms-causes/syc-20479963) 4. [Coronavirus infection by race](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-infection-by-race/faq-20488802) 5. [COVID-19 and pets](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/can-pets-get-coronavirus/faq-20486391) 6. [COVID-19 and vitamin D](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-and-vitamin-d/faq-20493088) 7. [COVID-19 and your mental health](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/mental-health-covid-19/art-20482731) 8. [COVID-19 drugs: Are there any that work?](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-drugs/faq-20485627) 9. [COVID-19 in babies and children](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-in-babies-and-children/art-20484405) 10. [COVID-19 travel advice](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-safe-travel-advice/art-20486965) 11. [COVID-19 vaccines for kids: What you need to know](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/covid-19-vaccines-for-kids/art-20513332) 12. [COVID-19 vaccines: Get the facts](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vaccine/art-20484859) 13. [COVID-19 variants](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/covid-variant/faq-20505779) 14. [COVID-19 vs. flu: Similarities and differences](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vs-flu/art-20490339) 15. [COVID-19, cold, allergies and the flu: What are the differences?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/covid-19-cold-flu-and-allergies-differences/art-20503981) 16. [COVID-19: How can I protect myself?](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/novel-coronavirus/faq-20478727) 17. [COVID-19: Who's at higher risk of serious symptoms?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-who-is-at-risk/art-20483301) 18. [Debunking COVID-19 myths](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-myths/art-20485720) 19. [Different types of COVID-19 vaccines: How they work](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/different-types-of-covid-19-vaccines/art-20506465) 20. [Fight coronavirus (COVID-19) transmission at home](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-transmission/art-20482397) 21. [Herd immunity and COVID-19: What you need to know](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/herd-immunity-and-coronavirus/art-20486808) 22. [How do COVID-19 antibody tests differ from diagnostic tests?](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/covid-antibody-tests/faq-20484429) 23. [How well do face masks protect against COVID-19?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-mask/art-20485449) 24. [Is hydroxychloroquine a treatment for COVID-19?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/hydroxychloroquine-treatment-covid-19/art-20555331) 25. [Long COVID: Lasting effects of COVID-19](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-long-term-effects/art-20490351) 26. [Loss of taste and smell](https://www.mayoclinic.org/healthy-lifestyle/healthy-aging/expert-answers/loss-of-taste-and-smell/faq-20058455) 27. [Mayo Clinic Minute: How dirty are common surfaces?](https://www.mayoclinic.org/diseases-conditions/coronavirus/multimedia/how-dirty-are-common-surfaces/vid-20483428) 28. [Mayo Clinic Minute: You're washing your hands all wrong](https://www.mayoclinic.org/diseases-conditions/coronavirus/multimedia/youre-washing-your-hands-all-wrong/vid-20483435) 29. [Nasal polyps](https://www.mayoclinic.org/diseases-conditions/nasal-polyps/symptoms-causes/syc-20351888) 30. [Pregnancy and COVID-19: What are the risks?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/pregnancy-and-covid-19/art-20482639) 31. [Safe outdoor activities during the COVID-19 pandemic](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/safe-activities-during-covid19/art-20489385) 32. [Safety tips for attending school during COVID-19](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/returning-safely-to-school-covid-19/art-20490441) 33. [Sex and COVID-19](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/sex-and-coronavirus/faq-20486572) 34. [Skull base tumors](https://www.mayoclinic.org/diseases-conditions/skull-base-tumors/symptoms-causes/syc-20581941) 35. [Treating COVID-19 at home: Care tips for you and others](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/treating-covid-19-at-home/art-20483273) 36. [Unusual symptoms of coronavirus](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-unusual-symptoms/faq-20487367) .
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