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| URL | https://www.mayoclinic.org/symptoms/loss-of-smell/basics/causes/sym-20050804 | |||||||||
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| Meta Title | Loss of smell (anosmia) Causes - Mayo Clinic | |||||||||
| Meta Description | A stuffy nose is one cause of this symptom. Learn about other causes and when it might be serious. | |||||||||
| Meta Canonical | null | |||||||||
| Boilerpipe Text | A stuffy nose from a cold is a common cause for a partial, brief loss of smell. A polyp or swelling inside the nose can lead to a loss of smell. Aging can cause a loss of smell, especially after age 60.
What is smell?
The nose and an area in the upper throat have special cells, called receptors, that discern odors. These receptors send a message to the brain about each smell. The brain then figures out what the smell is.
Any problem along the way can affect the sense of smell. Problems can include a stuffy nose; something that blocks the nose; swelling, called inflammation; nerve damage; or an issue with how the brain works.
Problems with the inner lining of the nose
Conditions that cause congestion or other issues inside the nose may include:
Acute sinusitis
Chronic sinusitis
Common cold
Coronavirus disease 2019 (COVID-19)
Hay fever
Influenza (flu)
Nonallergic rhinitis
Smoking
Blockages in the inside of the nose, called the nasal passages
Conditions that block the flow of air through the nose can include:
Nasal polyps
Tumors
Damage to your brain or nerves
The following can cause damage to the nerves to the area of the brain that picks up smells or to the brain itself to:
Aging
Alzheimer's disease
Being around toxic chemicals, such as those used in solvents
Brain aneurysm
Brain surgery
Brain tumor
Diabetes
Huntington's disease
Hypothyroidism (underactive thyroid)
Kallmann's syndrome (a rare genetic condition)
Korsakoff's psychosis, a brain condition caused by the lack of vitamin B-1, also called thiamin
Lewy body dementia
Medicines, such as some for high blood pressure, some antibiotics and antihistamines, and some nasal sprays
Multiple sclerosis
Parkinson's disease
Poor nutrition, such as too little zinc or vitamin B-12 in the diet
Pseudotumor cerebri (idiopathic intracranial hypertension)
Radiation therapy
Rhinoplasty
Traumatic brain injury
Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.
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Share
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Dec. 24, 2025
Ferri FF. T-differential diagnosis. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 6, 2023.
Smell disorders. National Institute on Deafness and Other Communication Disorders. https://www.nidcd.nih.gov/health/smell-disorders. Accessed April 6, 2023.
Lalwani AK. Olfactory dysfunction. In: Current Diagnosis & Treatment in Otolaryngology â Head & Neck Surgery. 4th ed. McGraw Hill; 2020. https://accessmedicine.mhmedical.com. Accessed April 6, 2023.
Lafreniere D. Taste and olfactory disorders in adults: Anatomy and etiology. https://www.uptodate.com/contents/search. Accessed April 7, 2023.
Anosmia. Merck Manual Professional Version. https://www.merckmanuals.com/professional/ear,-nose,-and-throat-disorders/approach-to-the-patient-with-nasal-and-pharyngeal-symptoms/anosmia. Accessed April 6, 2023.
See also
Bardet-Biedl syndrome (BBS)
Chronic sinusitis
Coronavirus disease 2019 (COVID-19)
Coronavirus infection by race
COVID-19 and pets
COVID-19 and vitamin D
COVID-19 and your mental health
COVID-19 drugs: Are there any that work?
COVID-19 in babies and children
COVID-19 travel advice
COVID-19 vaccines for kids: What you need to know
COVID-19 vaccines: Get the facts
COVID-19 variants
COVID-19 vs. flu: Similarities and differences
COVID-19, cold, allergies and the flu: What are the differences?
COVID-19: How can I protect myself?
COVID-19: Who's at higher risk of serious symptoms?
Debunking COVID-19 myths
Different types of COVID-19 vaccines: How they work
Fight coronavirus (COVID-19) transmission at home
Herd immunity and COVID-19: What you need to know
How do COVID-19 antibody tests differ from diagnostic tests?
How well do face masks protect against COVID-19?
Is hydroxychloroquine a treatment for COVID-19?
Long COVID: Lasting effects of COVID-19
Loss of taste and smell
Mayo Clinic Minute: How dirty are common surfaces?
Mayo Clinic Minute: You're washing your hands all wrong
Nasal polyps
Pregnancy and COVID-19: What are the risks?
Safe outdoor activities during the COVID-19 pandemic
Safety tips for attending school during COVID-19
Sex and COVID-19
Skull base tumors
Treating COVID-19 at home: Care tips for you and others
Unusual symptoms of coronavirus
. | |||||||||
| Markdown | null | |||||||||
| Readable Markdown | A stuffy nose from a cold is a common cause for a partial, brief loss of smell. A polyp or swelling inside the nose can lead to a loss of smell. Aging can cause a loss of smell, especially after age 60.
### What is smell?
The nose and an area in the upper throat have special cells, called receptors, that discern odors. These receptors send a message to the brain about each smell. The brain then figures out what the smell is.
Any problem along the way can affect the sense of smell. Problems can include a stuffy nose; something that blocks the nose; swelling, called inflammation; nerve damage; or an issue with how the brain works.
### Problems with the inner lining of the nose
Conditions that cause congestion or other issues inside the nose may include:
1. [Acute sinusitis](https://www.mayoclinic.org/diseases-conditions/acute-sinusitis/symptoms-causes/syc-20351671)
2. [Chronic sinusitis](https://www.mayoclinic.org/diseases-conditions/chronic-sinusitis/symptoms-causes/syc-20351661)
3. [Common cold](https://www.mayoclinic.org/diseases-conditions/common-cold/symptoms-causes/syc-20351605)
4. [Coronavirus disease 2019 (COVID-19)](https://www.mayoclinic.org/diseases-conditions/coronavirus/symptoms-causes/syc-20479963)
5. [Hay fever](https://www.mayoclinic.org/diseases-conditions/hay-fever/symptoms-causes/syc-20373039)
6. [Influenza (flu)](https://www.mayoclinic.org/diseases-conditions/flu/symptoms-causes/syc-20351719)
7. [Nonallergic rhinitis](https://www.mayoclinic.org/diseases-conditions/nonallergic-rhinitis/symptoms-causes/syc-20351229)
8. Smoking
### Blockages in the inside of the nose, called the nasal passages
Conditions that block the flow of air through the nose can include:
1. [Nasal polyps](https://www.mayoclinic.org/diseases-conditions/nasal-polyps/symptoms-causes/syc-20351888)
2. Tumors
### Damage to your brain or nerves
The following can cause damage to the nerves to the area of the brain that picks up smells or to the brain itself to:
1. Aging
2. [Alzheimer's disease](https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/symptoms-causes/syc-20350447)
3. Being around toxic chemicals, such as those used in solvents
4. [Brain aneurysm](https://www.mayoclinic.org/diseases-conditions/brain-aneurysm/symptoms-causes/syc-20361483)
5. Brain surgery
6. [Brain tumor](https://www.mayoclinic.org/diseases-conditions/brain-tumor/symptoms-causes/syc-20350084)
7. [Diabetes](https://www.mayoclinic.org/diseases-conditions/diabetes/symptoms-causes/syc-20371444)
8. [Huntington's disease](https://www.mayoclinic.org/diseases-conditions/huntingtons-disease/symptoms-causes/syc-20356117)
9. [Hypothyroidism (underactive thyroid)](https://www.mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-20350284)
10. Kallmann's syndrome (a rare genetic condition)
11. Korsakoff's psychosis, a brain condition caused by the lack of vitamin B-1, also called thiamin
12. [Lewy body dementia](https://www.mayoclinic.org/diseases-conditions/lewy-body-dementia/symptoms-causes/syc-20352025)
13. Medicines, such as some for high blood pressure, some antibiotics and antihistamines, and some nasal sprays
14. [Multiple sclerosis](https://www.mayoclinic.org/diseases-conditions/multiple-sclerosis/symptoms-causes/syc-20350269)
15. [Parkinson's disease](https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055)
16. Poor nutrition, such as too little zinc or vitamin B-12 in the diet
17. [Pseudotumor cerebri (idiopathic intracranial hypertension)](https://www.mayoclinic.org/diseases-conditions/pseudotumor-cerebri/symptoms-causes/syc-20354031)
18. [Radiation therapy](https://www.mayoclinic.org/tests-procedures/radiation-therapy/about/pac-20385162)
19. [Rhinoplasty](https://www.mayoclinic.org/tests-procedures/rhinoplasty/about/pac-20384532)
20. [Traumatic brain injury](https://www.mayoclinic.org/diseases-conditions/traumatic-brain-injury/symptoms-causes/syc-20378557)
Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.
## From Mayo Clinic to your inbox
Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. [Click here for an email preview.](https://links.e.response.mayoclinic.org/EmailPreview-GeneralHealth)
Email
We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our [Notice of Privacy Practices](https://mcforms.mayo.edu/mc5200-mc5299/mc5256-01.pdf). You may opt out of email communications at any time by clicking on the unsubscribe link in the email.
- [Share](https://www.facebook.com/sharer.php?u=https://www.mayoclinic.org/symptoms/loss-of-smell/basics/causes/sym-20050804)
- [Tweet](http://twitter.com/intent/tweet?url=https://www.mayoclinic.org/symptoms/loss-of-smell/basics/causes/sym-20050804&text=Loss+of+smell+\(anosmia\)+Causes)
Dec. 24, 2025
1. Ferri FF. T-differential diagnosis. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 6, 2023.
2. Smell disorders. National Institute on Deafness and Other Communication Disorders. https://www.nidcd.nih.gov/health/smell-disorders. Accessed April 6, 2023.
3. Lalwani AK. Olfactory dysfunction. In: Current Diagnosis & Treatment in Otolaryngology â Head & Neck Surgery. 4th ed. McGraw Hill; 2020. https://accessmedicine.mhmedical.com. Accessed April 6, 2023.
4. Lafreniere D. Taste and olfactory disorders in adults: Anatomy and etiology. https://www.uptodate.com/contents/search. Accessed April 7, 2023.
5. Anosmia. Merck Manual Professional Version. https://www.merckmanuals.com/professional/ear,-nose,-and-throat-disorders/approach-to-the-patient-with-nasal-and-pharyngeal-symptoms/anosmia. Accessed April 6, 2023.
## See also
1. [Bardet-Biedl syndrome (BBS)](https://www.mayoclinic.org/diseases-conditions/bardet-biedl-syndrome/symptoms-causes/syc-20586227)
2. [Chronic sinusitis](https://www.mayoclinic.org/diseases-conditions/chronic-sinusitis/symptoms-causes/syc-20351661)
3. [Coronavirus disease 2019 (COVID-19)](https://www.mayoclinic.org/diseases-conditions/coronavirus/symptoms-causes/syc-20479963)
4. [Coronavirus infection by race](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-infection-by-race/faq-20488802)
5. [COVID-19 and pets](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/can-pets-get-coronavirus/faq-20486391)
6. [COVID-19 and vitamin D](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-and-vitamin-d/faq-20493088)
7. [COVID-19 and your mental health](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/mental-health-covid-19/art-20482731)
8. [COVID-19 drugs: Are there any that work?](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-drugs/faq-20485627)
9. [COVID-19 in babies and children](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-in-babies-and-children/art-20484405)
10. [COVID-19 travel advice](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-safe-travel-advice/art-20486965)
11. [COVID-19 vaccines for kids: What you need to know](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/covid-19-vaccines-for-kids/art-20513332)
12. [COVID-19 vaccines: Get the facts](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vaccine/art-20484859)
13. [COVID-19 variants](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/covid-variant/faq-20505779)
14. [COVID-19 vs. flu: Similarities and differences](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vs-flu/art-20490339)
15. [COVID-19, cold, allergies and the flu: What are the differences?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/covid-19-cold-flu-and-allergies-differences/art-20503981)
16. [COVID-19: How can I protect myself?](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/novel-coronavirus/faq-20478727)
17. [COVID-19: Who's at higher risk of serious symptoms?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-who-is-at-risk/art-20483301)
18. [Debunking COVID-19 myths](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-myths/art-20485720)
19. [Different types of COVID-19 vaccines: How they work](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/different-types-of-covid-19-vaccines/art-20506465)
20. [Fight coronavirus (COVID-19) transmission at home](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-transmission/art-20482397)
21. [Herd immunity and COVID-19: What you need to know](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/herd-immunity-and-coronavirus/art-20486808)
22. [How do COVID-19 antibody tests differ from diagnostic tests?](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/covid-antibody-tests/faq-20484429)
23. [How well do face masks protect against COVID-19?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-mask/art-20485449)
24. [Is hydroxychloroquine a treatment for COVID-19?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/hydroxychloroquine-treatment-covid-19/art-20555331)
25. [Long COVID: Lasting effects of COVID-19](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-long-term-effects/art-20490351)
26. [Loss of taste and smell](https://www.mayoclinic.org/healthy-lifestyle/healthy-aging/expert-answers/loss-of-taste-and-smell/faq-20058455)
27. [Mayo Clinic Minute: How dirty are common surfaces?](https://www.mayoclinic.org/diseases-conditions/coronavirus/multimedia/how-dirty-are-common-surfaces/vid-20483428)
28. [Mayo Clinic Minute: You're washing your hands all wrong](https://www.mayoclinic.org/diseases-conditions/coronavirus/multimedia/youre-washing-your-hands-all-wrong/vid-20483435)
29. [Nasal polyps](https://www.mayoclinic.org/diseases-conditions/nasal-polyps/symptoms-causes/syc-20351888)
30. [Pregnancy and COVID-19: What are the risks?](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/pregnancy-and-covid-19/art-20482639)
31. [Safe outdoor activities during the COVID-19 pandemic](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/safe-activities-during-covid19/art-20489385)
32. [Safety tips for attending school during COVID-19](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/returning-safely-to-school-covid-19/art-20490441)
33. [Sex and COVID-19](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/sex-and-coronavirus/faq-20486572)
34. [Skull base tumors](https://www.mayoclinic.org/diseases-conditions/skull-base-tumors/symptoms-causes/syc-20581941)
35. [Treating COVID-19 at home: Care tips for you and others](https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/treating-covid-19-at-home/art-20483273)
36. [Unusual symptoms of coronavirus](https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/coronavirus-unusual-symptoms/faq-20487367)
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