🕷️ Crawler Inspector

URL Lookup

Direct Parameter Lookup

Raw Queries and Responses

1. Shard Calculation

Query:
Response:
Calculated Shard: 40 (from laksa016)

2. Crawled Status Check

Query:
Response:

3. Robots.txt Check

Query:
Response:

4. Spam/Ban Check

Query:
Response:

5. Seen Status Check

ℹ️ Skipped - page is already crawled

📄
INDEXABLE
CRAWLED
19 days ago
🤖
ROBOTS ALLOWED

Page Info Filters

FilterStatusConditionDetails
HTTP statusPASSdownload_http_code = 200HTTP 200
Age cutoffPASSdownload_stamp > now() - 6 MONTH0.7 months ago
History dropPASSisNull(history_drop_reason)No drop reason
Spam/banPASSfh_dont_index != 1 AND ml_spam_score = 0ml_spam_score=0
CanonicalPASSmeta_canonical IS NULL OR = '' OR = src_unparsedNot set

Page Details

PropertyValue
URLhttps://www.mayoclinic.org/drugs-supplements-melatonin/art-20363071
Last Crawled2026-04-01 03:49:18 (19 days ago)
First Indexed2017-10-20 12:37:07 (8 years ago)
HTTP Status Code200
Meta TitleMelatonin - Mayo Clinic
Meta DescriptionFind out how melatonin can promote sleep and understand possible side effects of this supplement.
Meta Canonicalnull
Boilerpipe Text
Melatonin taken orally in appropriate amounts is generally safe. Melatonin can cause: Headache Dizziness Nausea Drowsiness Less common melatonin side effects might include short-lasting feelings of depression, mild tremor, mild anxiety, abdominal cramps, irritability, reduced alertness, confusion or disorientation. Because melatonin can cause daytime drowsiness, don't drive or use machinery within five hours of taking the supplement. Don't use melatonin if you have an autoimmune disease.
Markdown
[Skip to content](https://www.mayoclinic.org/drugs-supplements-melatonin/art-20363071#main-content) [![Mayo Clinic Home Page](https://assets.mayoclinic.org/content/dam/mayoclinic/images/logos/mayo-clinic-logo.svg)](https://www.mayoclinic.org/) [![Mayo Clinic Home Page](https://assets.mayoclinic.org/content/dam/mayoclinic/images/logos/mayo-clinic-logo.svg)](https://www.mayoclinic.org/) - [Request appointment](https://www.mayoclinic.org/appointments) - [Log in](https://onlineservices.mayoclinic.org/content/staticpatient/showpage/patientonline) - Search - Menu [Request appointment](https://www.mayoclinic.org/appointments) [Donate](https://give.mayoclinic.org/give/609586/#!/donation/checkout) [Diseases & conditions](https://www.mayoclinic.org/diseases-conditions) [Find a doctor](https://www.mayoclinic.org/appointments/find-a-doctor) - Care at Mayo Clinic [Patient-Centered Care](https://www.mayoclinic.org/patient-centered-care) [About Mayo Clinic](https://www.mayoclinic.org/about-mayo-clinic) [Request Appointment](https://www.mayoclinic.org/appointments) [Find a Doctor](https://www.mayoclinic.org/appointments/find-a-doctor) [Locations](https://www.mayoclinic.org/locations) [Clinical Trials](https://www.mayo.edu/research/clinical-trials) [Connect to Support Groups](https://connect.mayoclinic.org/) [Patient & Visitor Guide](https://www.mayoclinic.org/patient-visitor-guide) [Billing & Insurance](https://www.mayoclinic.org/billing-insurance) [Departments & Centers](https://www.mayoclinic.org/departments-centers) [International Services](https://www.mayoclinic.org/international) [Contact Us](https://www.mayoclinic.org/about-mayo-clinic/contact) [Patient & Visitor Guide](https://www.mayoclinic.org/patient-visitor-guide) ![](https://assets.mayoclinic.org/content/dam/media/global/images/2023/06/26/pt-visitor-Getty-1419492732-415x275.jpg) - Health Library [Diseases & Conditions](https://www.mayoclinic.org/diseases-conditions) [Symptoms](https://www.mayoclinic.org/symptoms) [Tests & Procedures](https://www.mayoclinic.org/tests-procedures) [Drugs & Supplements](https://www.mayoclinic.org/drugs-supplements) [Healthy Lifestyle](https://www.mayoclinic.org/healthy-lifestyle) [Mayo Clinic Health Letter & Books](https://mcpress.mayoclinic.org/product/healthletter/?utm_source=MC-DotOrg-PC-Top&utm_medium=PromoCard&utm_campaign=HealthLetter&utm_content=HL_1) [Mayo Clinic Health Letter & Books](https://mcpress.mayoclinic.org/product/healthletter/?utm_source=MC-DotOrg-PC-Top&utm_medium=PromoCard&utm_campaign=HealthLetter&utm_content=HL_1) ![](https://assets.mayoclinic.org/content/dam/media/global/images/2025/03/19/1710753_3980687_0060.png) - For Medical Professionals [Medical Professional Resources](https://www.mayoclinic.org/medical-professionals) [Refer a Patient](https://www.mayoclinic.org/medical-professionals/provider-relations/refer-patient) [Continuing Medical Education](https://ce.mayo.edu/) [Mayo Clinic Laboratories](https://www.mayocliniclabs.com/) [Video Center](https://medprofvideos.mayoclinic.org/) [Journals & Publications](https://www.mayoclinic.org/medical-professionals/publications) [Mayo Clinic Alumni Association](https://alumniassociation.mayo.edu/) [Continuing Medical Education](https://ce.mayo.edu/) ![](https://assets.mayoclinic.org/content/dam/media/global/images/2023/06/26/cont-ed-1676659-3734290-0048-C-415x275.jpg) - Research & Education at Mayo Clinic ## Research [Research at Mayo Clinic](https://www.mayo.edu/research) [Research Faculty](https://www.mayo.edu/research/faculty) [Laboratories](https://www.mayo.edu/research/labs) [Core Facilities](https://www.mayo.edu/research/core-facilities/overview) [Centers & Programs](https://www.mayo.edu/research/centers-programs) [Departments & Divisions](https://www.mayo.edu/research/departments-divisions) [Clinical Trials](https://www.mayo.edu/research/clinical-trials) [Institutional Review Board](https://www.mayo.edu/research/institutional-review-board/overview) [Postdoctoral Fellowships](https://jobs.mayoclinic.org/search-jobs/postdoctoral%20fellowships/33647/1) [Training Grant Programs](https://www.mayo.edu/research/training-grant-programs) ## Education [Mayo Clinic College of Medicine and Science](https://college.mayo.edu/) [Mayo Clinic Graduate School of Biomedical Sciences](https://college.mayo.edu/academics/biomedical-research-training/) [Mayo Clinic Alix School of Medicine](https://college.mayo.edu/academics/mayo-clinic-alix-school-of-medicine/) [Mayo Clinic School of Graduate Medical Education](https://college.mayo.edu/academics/residencies-and-fellowships/) [Mayo Clinic School of Health Sciences](https://college.mayo.edu/academics/health-sciences-education/) [Mayo Clinic School of Continuous Professional Development](https://ce.mayo.edu/) [Mayo Clinic College of Medicine and Science](https://college.mayo.edu/) ![](https://assets.mayoclinic.org/content/dam/media/global/images/2023/06/26/mccms-Getty-1082003662-415x275.jpg) - Giving to Mayo Clinic [Give Now](https://give.mayoclinic.org/campaign/740556/donate) [Giving to Mayo Clinic](https://www.mayoclinic.org/giving-to-mayo-clinic) [Frequently Asked Questions](https://www.mayoclinic.org/giving-to-mayo-clinic/contact-us/frequently-asked-questions) [Contact Us to Give](https://www.mayoclinic.org/giving-to-mayo-clinic/contact-us) [Make a Donation](https://give.mayoclinic.org/campaign/740556/donate) ![](https://assets.mayoclinic.org/content/dam/media/global/images/2023/10/23/giving-to-mayo-em100063715-p-195580295-415x275.png) Search for a disease or condition . Type 3 or more letters to display suggested search options. When results are available, use up and down arrow keys to navigate. Press space key to fill the input with the suggestion or enter key to search with the suggestion.Search by keyword or phrase Search [Home](https://www.mayoclinic.org/) 1. [Home](https://www.mayoclinic.org/) 2. [Drugs and Supplements](https://www.mayoclinic.org/drugs-supplements) 3. Melatonin # Melatonin [By Mayo Clinic Staff](https://www.mayoclinic.org/about-this-site/meet-our-medical-editors) Aug. 13, 2025 ## Overview Melatonin is a hormone in your body that plays a role in sleep. The production and release of melatonin in the brain is connected to time of day, increasing when it's dark and decreasing when it's light. Melatonin production declines with age. Melatonin is also available as a supplement, typically as an oral tablet or capsule. Most melatonin supplements are made in a lab. People commonly use melatonin for sleep disorders, such as insomnia and jet lag. ## What the research says Research on melatonin use for specific conditions shows: - **Circadian rhythm sleep disorders in the blind.** Melatonin can help improve these disorders in adults and children. - **Delayed sleep phase (delayed sleep-wake phase sleep disorder).** In this disorder, your sleep pattern is delayed two hours or more from a conventional sleep pattern, causing you to go to sleep later and wake up later. Research shows that melatonin reduces the length of time needed to fall asleep and advances the start of sleep in adults and children with this condition. Talk to your child's doctor before giving melatonin to a child. - **Insomnia.** Research suggests that melatonin might slightly reduce the time it takes to fall asleep, but its effects on sleep quality and total sleep time aren't clear. Melatonin might be more beneficial for older adults who could be melatonin deficient. - **Jet lag.** Evidence shows that melatonin can improve jet lag symptoms, such as alertness and daytime sleepiness. - **Shift work disorder.** It's not clear whether melatonin can improve daytime sleep quality and duration in people whose jobs require them to work outside the traditional morning to evening schedule. - **Sleep disorders in children.** Small studies have suggested melatonin might help treat sleep disturbances in children with a number of disabilities. However, good bedtime habits are usually recommended as an initial treatment. Talk to your child's doctor before giving melatonin to a child. Research suggests that melatonin might reduce evening confusion and restlessness in people with Alzheimer's disease, but it doesn't seem to improve cognition. ## Our take Generally safe Your body likely produces enough melatonin for its general needs. However, evidence suggests that melatonin supplements promote sleep and are safe for short-term use. Melatonin can be used to treat delayed sleep phase and circadian rhythm sleep disorders in the blind and provide some insomnia relief. Treat melatonin as you would any sleeping pill and use it under your doctor's supervision. ## Safety and side effects Melatonin taken orally in appropriate amounts is generally safe. Melatonin can cause: - Headache - Dizziness - Nausea - Drowsiness Less common melatonin side effects might include short-lasting feelings of depression, mild tremor, mild anxiety, abdominal cramps, irritability, reduced alertness, confusion or disorientation. Because melatonin can cause daytime drowsiness, don't drive or use machinery within five hours of taking the supplement. Don't use melatonin if you have an autoimmune disease. ## Interactions Possible drug interactions include: - **Anticoagulants and anti-platelet drugs, herbs and supplements.** These types of drugs, herbs and supplements reduce blood clotting. Combining use of melatonin with them might increase the risk of bleeding. - **Anticonvulsants.** Melatonin might inhibit the effects of anticonvulsants and increase the frequency of seizures particularly in children with neurological disabilities. - **Blood pressure drugs.** Melatonin might worsen blood pressure in people taking blood pressure medications. - **Central nervous system (CNS) depressants.** Melatonin use with these medications might cause an additive sedative effect. - **Diabetes medications.** Melatonin might affect sugar levels. If you take diabetes medications, talk to your doctor before using melatonin. - **Contraceptive drugs.** Use of contraceptive drugs with melatonin might cause an additive sedative effect and increase possible side effects of melatonin. - **Cytochrome P450 1A2 (CYP1A2) and cytochrome P450 2C19 (CPY2C19) substrates.** Use melatonin cautiously if you take drugs such as diazepam (Valium, Valtoco, others) and others that are affected by these enzymes. - **Fluvoxamine (Luvox).** This medication used to treat obsessive-compulsive disorder can increase melatonin levels, causing unwanted excessive drowsiness. - **Immunosuppressants.** Melatonin can stimulate immune function and interfere with immunosuppressive therapy. - **Seizure threshold lowering drugs.** Taking melatonin with these drugs might increase the risk of seizures. ## More information [About 'Our take'](https://www.mayoclinic.org/about-our-take/art-20380878) Show references 1. Melatonin: What you need to know. National Center for Complementary and Integrative Health. https://www.nccih.nih.gov/health/melatonin-what-you-need-to-know. Accessed Jan. 24, 2021. 2. Melatonin. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Jan. 24, 2021. 3. Melatonin. Facts & Comparisons eAnswers. https://www.wolterskluwercdi.com/facts-comparisons-online/. Accessed Jan. 24, 2021. 4. Melatonin. IBM Micromedex. https://www.microdemexsolutions.com. Accessed Jan. 24, 2021. 5. Pizzorono JE, et al., eds. Melatonin. In: Textbook of Natural Medicine. 5th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed Jan. 24, 2021. 6. Kellerman RD, et al. Popular herbs and nutritional supplements. In: Conn's Current Therapy 2021. Elsevier; 2021. https://www.clinicalkey.com. Accessed Jan. 24, 2021. 7. Wurtman R. Physiology and available preparations of melatonin. https://www.uptodate.com/contents/search. Accessed Jan. 24, 2021. [Print](https://www.mayoclinic.org/drugs-supplements-melatonin/art-20363071?p=1) ## From Mayo Clinic to your inbox Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. [Click here for an email preview.](https://links.e.response.mayoclinic.org/EmailPreview-GeneralHealth) Learn more about Mayo Clinic’s use of data. We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our [Notice of Privacy Practices](https://mcforms.mayo.edu/mc5200-mc5299/mc5256-01.pdf). You may opt out of email communications at any time by clicking on the unsubscribe link in the email. [Skip Advertisement](https://www.mayoclinic.org/drugs-supplements-melatonin/art-20363071#advertising-disclaimer) ## Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. ### Advertising & Sponsorship - [Policy](https://www.mayoclinic.org/about-this-site/advertising-sponsorship-policy.html) - [Opportunities](https://www.mayoclinic.org/about-this-site/advertising-sponsorship.html) - [Ad Choices](https://optout.aboutads.info/) *** ## Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from [Mayo Clinic Press](https://mcpress.mayoclinic.org/?utm_source=MC-DotOrg-Text&utm_medium=Link&utm_campaign=MC-Press&utm_content=MCPRESS). - [Mayo Clinic on Incontinence](https://order.store.mayoclinic.com/flex/mmv/incon01/?utm_source=MC-DotOrg-Text&utm_medium=Link&utm_campaign=Incontinence-Book&utm_content=INC) - [The Essential Diabetes Book](https://order.store.mayoclinic.com/flex/mmv/ESDIAB1/?altkey=ESMCPRC&utm_source=MC-DotOrg-Text&utm_medium=Link&utm_campaign=Diabetes-Book&utm_content=EDIAB) - [Mayo Clinic on Hearing and Balance](https://order.store.mayoclinic.com/flex/mmv/HRBAL02/?altkey=HRMCPRC&utm_source=MC-DotOrg-Text&utm_medium=Link&utm_campaign=Hearing-Book&utm_content=HEAR) - [FREE Mayo Clinic Diet Assessment](https://diet.mayoclinic.org/us/diet-assessment/diet-assessment/?profile=true&promo=65-qtr&utm_source=Mayo&utm_medium=Display&utm_campaign=text_link) - [Mayo Clinic Health Letter - FREE book](https://order.store.mayoclinic.com/flex/mmv/HLFBOOK/?altkey=HLFBORG&utm_source=MC-DotOrg-Text&utm_medium=Link&utm_campaign=HealthLetter-Digital&utm_content=HL_FREEBOOK) [Skip Advertisement](https://www.mayoclinic.org/drugs-supplements-melatonin/art-20363071#promo) ## Advertisement Close Advertisement ART-20363071 *** [Home](https://www.mayoclinic.org/) 1. [Home](https://www.mayoclinic.org/) 2. [Drugs and Supplements](https://www.mayoclinic.org/drugs-supplements) 3. Melatonin ![](https://assets.mayoclinic.org/content/dam/mayoclinic/images/icons/person-physician.svg) ## National Doctors’ Day is March 30\! [Give Now\!](https://give.mayoclinic.org/campaign/769678/donate?utm_source=devappeal&utm_medium=devweb&utm_campaign=devdoctorsday&preset1=50&preset2=100&preset3=250&preset4=1000&amount=100&currency=USD&c_src=26R031WG1MWV90Z11B) Your gift to celebrate this day advances our doctors’ lifesaving work. [Give Now\!](https://give.mayoclinic.org/campaign/769678/donate?utm_source=devappeal&utm_medium=devweb&utm_campaign=devdoctorsday&preset1=50&preset2=100&preset3=250&preset4=1000&amount=100&currency=USD&c_src=26R031WG1MWV90Z11B) - [Find a doctor](https://www.mayoclinic.org/appointments/find-a-doctor) - [Explore careers](https://jobs.mayoclinic.org/) - [Sign up for free e-newsletters](https://links.e.response.mayoclinic.org/preferencecenter) ## [About Mayo Clinic](https://www.mayoclinic.org/about-mayo-clinic) - [About this Site](https://www.mayoclinic.org/about-this-site) - [Contact Us](https://www.mayoclinic.org/about-mayo-clinic/contact) - [Locations](https://www.mayoclinic.org/locations) - [Health Information Policy](https://www.mayoclinic.org/about-this-site/health-information-policy) - [Medicare Accountable Care Organization (ACO)](https://www.mayoclinic.org/about-mayo-clinic/aco) - [Media Requests](https://newsnetwork.mayoclinic.org/newsroom/) - [News Network](https://newsnetwork.mayoclinic.org/) - [Price Transparency](https://www.mayoclinic.org/billing-insurance/price-estimates/chargemaster) ## [Medical Professionals](https://www.mayoclinic.org/medical-professionals) - [AskMayoExpert](https://askmayoexpert.mayoclinic.org/) - [Clinical Trials](https://www.mayo.edu/research/clinical-trials) - [Mayo Clinic Alumni Association](https://alumniassociation.mayo.edu/) - [Refer a Patient](https://www.mayoclinic.org/medical-professionals/provider-relations/refer-patient) ## [Businesses](https://businessdevelopment.mayoclinic.org/) - [Executive Health Program](https://www.mayoclinic.org/executive-health) - [International Business Collaborations](https://www.mayoclinic.org/about-mayo-clinic/international-business-collaborations) - [Facilities & Real Estate](https://www.mayoclinic.org/about-mayo-clinic/facilities-and-real-estate) - [Supplier Information](https://www.mayoclinic.org/about-mayo-clinic/supplier-information) ## [Students](https://college.mayo.edu/) - [Admissions Requirements](https://college.mayo.edu/admissions-and-tuition/) - [Degree Programs](https://college.mayo.edu/academics/) - [Student & Faculty Portal](https://edlinkplus.mayo.edu/) ## [Researchers](https://www.mayo.edu/research) - [Research Faculty](https://www.mayo.edu/research/faculty) - [Laboratories](https://www.mayo.edu/research/labs) ## [International Patients](https://www.mayoclinic.org/international) - [Appointments](https://www.mayoclinic.org/international/contact) - [Financial Services](https://www.mayoclinic.org/international/costs-and-insurance) - [Representative Offices](https://www.mayoclinic.org/international/support/representative-offices) ## [Charitable Care & Financial Assistance](https://www.mayoclinic.org/billing-insurance/financial-assistance) [Community Health Needs Assessment](https://www.communityengagement.mayoclinic.org/community-health-needs-assessment) - [Financial Assistance Documents – Arizona](https://www.mayoclinic.org/billing-insurance/financial-assistance/arizona-documents) - [Financial Assistance Documents – Florida](https://www.mayoclinic.org/billing-insurance/financial-assistance/florida-documents) - [Financial Assistance Documents – Minnesota](https://www.mayoclinic.org/billing-insurance/financial-assistance/minnesota-documents) *** ## Follow Mayo Clinic - [X](https://x.com/mayoclinic) - [YouTube](https://www.youtube.com/user/mayoclinic) - [Facebook](https://www.facebook.com/MayoClinic) - [LinkedIn](https://www.linkedin.com/company/mayo-clinic) - [Instagram](https://www.instagram.com/mayoclinic/) ## Get the Mayo Clinic app - [![Android App on Google Play](https://assets.mayoclinic.org/content/dam/mayoclinic/images/badges/Google_Play_Store_badge_EN.svg)](https://play.google.com/store/apps/details?id=com.mayoclinic.patient&hl=en%27) - [![Apple Download on the App Store](https://assets.mayoclinic.org/content/dam/mayoclinic/images/badges/App_Store_Badge_EN.svg)](https://apps.apple.com/us/app/mayo-clinic/id523220194) - [Terms & Conditions](https://www.mayoclinic.org/about-this-site/terms-conditions-use-policy) - [Privacy Policy](https://www.mayoclinic.org/about-this-site/privacy-policy) - [Notice of Privacy Practices](https://mcforms.mayo.edu/mc5200-mc5299/mc5256-01.pdf) - [Notice of Nondiscrimination](https://mcforms.mayo.edu/mc2500-mc2599/mc2570-61.pdf) - [Digital Accessibility Statement](https://www.mayoclinic.org/about-this-site/accessibility-statement) - [Advertising & Sponsorship Policy](https://www.mayoclinic.org/about-this-site/advertising-sponsorship-policy) - [Site Map](https://www.mayoclinic.org/site-help/site-map) - [Manage Cookies](https://www.mayoclinic.org/) - [Terms and Conditions](https://www.mayoclinic.org/about-this-site/terms-conditions-use-policy) - [Privacy Policy](https://www.mayoclinic.org/about-this-site/privacy-policy) - [Notice of Privacy Practices](https://mcforms.mayo.edu/mc5200-mc5299/mc5256-01.pdf) - [Notice of Nondiscrimination](https://mcforms.mayo.edu/mc2500-mc2599/mc2570-61.pdf) - [Digital Accessibility Statement](https://www.mayoclinic.org/about-this-site/accessibility-statement) - [Advertising and Sponsorship Policy](https://www.mayoclinic.org/about-this-site/advertising-sponsorship-policy) - [Site Map](https://www.mayoclinic.org/site-help/site-map) - [Manage Cookies](https://www.mayoclinic.org/) *** Language: English - [English](https://www.mayoclinic.org/drugs-supplements-melatonin/art-20363071) - [Español](https://www.mayoclinic.org/es/drugs-supplements-melatonin/art-20363071) - [العربية](https://www.mayoclinic.org/ar/drugs-supplements-melatonin/art-20363071) - [简体中文](https://www.mayoclinic.org/zh-hans/drugs-supplements-melatonin/art-20363071) © 1998-2026 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Language: English - [English](https://www.mayoclinic.org/drugs-supplements-melatonin/art-20363071) - [Español](https://www.mayoclinic.org/es/drugs-supplements-melatonin/art-20363071) - [العربية](https://www.mayoclinic.org/ar/drugs-supplements-melatonin/art-20363071) - [简体中文](https://www.mayoclinic.org/zh-hans/drugs-supplements-melatonin/art-20363071)
Readable Markdown
Melatonin taken orally in appropriate amounts is generally safe. Melatonin can cause: - Headache - Dizziness - Nausea - Drowsiness Less common melatonin side effects might include short-lasting feelings of depression, mild tremor, mild anxiety, abdominal cramps, irritability, reduced alertness, confusion or disorientation. Because melatonin can cause daytime drowsiness, don't drive or use machinery within five hours of taking the supplement. Don't use melatonin if you have an autoimmune disease.
Shard40 (laksa)
Root Hash1608882045018104440
Unparsed URLorg,mayoclinic!www,/drugs-supplements-melatonin/art-20363071 s443