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URLhttps://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease
Last Crawled2026-04-16 09:51:29 (2 days ago)
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Meta Title10 Signs You May Have Kidney Disease | National Kidney Foundation
Meta DescriptionKidney disease affects more than 35 million Americans. 90% don't know they have it. Learn the symptoms, risk factors, and how to get tested for early detection.
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December 17, 2020 An estimated 35.5 million U.S. adults have kidney disease. Most don’t know they have it. While the only way to know if you have kidney disease is to get tested, there are signs to watch for. Kidney Disease Risk Factors If you’re at risk for kidney disease due to high blood pressure , diabetes , a family history of kidney failure, or if you’re older than age 60, it’s important to get tested annually for kidney disease. “There are a number of physical signs of kidney disease, but sometimes people attribute them to other conditions,” said Dr. Joseph Vassalotti, Chief Medical Officer at the NKF. “Those with kidney disease tend not to experience symptoms until the very late stages, when the kidneys are failing or when there are large amounts of protein in the urine. This is one of the reasons why only 10% of people with chronic kidney disease know that they have it.” Are you at risk of kidney disease? Take this one-minute quiz to find out . Kidney Disease Testing 1. Less Energy or Trouble Concentrating A severe decrease in kidney function can lead to a buildup of toxins and impurities in the blood. This can cause people to feel tired or weak and can make it hard to concentrate. Another complication of kidney disease is anemia, which can cause weakness and fatigue. Learn more about anemia . 2. Trouble sleeping When the kidneys aren't filtering properly, toxins stay in the blood rather than leaving the body through the urine. This can make it difficult to sleep. There is also a link between obesity and chronic kidney disease, and sleep apnea is more common in those with kidney disease, compared with the general population.  3. Dry and itchy skin Healthy kidneys do many important jobs. They remove wastes and extra fluid from your body, help make red blood cells, keep bones strong, and work to maintain the right amount of minerals in your blood. Dry and itchy skin can be a sign of the mineral and bone disease that often accompanies advanced kidney disease, or when the kidneys are no longer able to keep the right balance of minerals and nutrients in your blood. Learn more about itchy skin and kidney disease . Join the NKF Blog Newsletter Get inspirational stories and kidney disease resources delivered to your inbox every month. You'll gain practical insights and expert advice to help you better understand and manage your kidney health no matter where you are on your kidney journey. Subscribe today. 4. Urinating more frequently If you feel the need to urinate more often, especially at night, this can be a sign of kidney disease. When the kidney's filters are damaged, it can cause an increase in the urge to urinate. Sometimes this can also be a sign of a urinary infection or enlarged prostate in men. 5. Blood in urine Healthy kidneys typically keep the blood cells in the body when filtering wastes from the blood to create urine, but when the kidney's filters have been damaged, these blood cells can start to "leak" out into the urine. In addition to signaling kidney disease, blood in the urine can be indicative of tumors, kidney stones, or an infection. Learn more about blood in urine . 6. Foamy urine Excessive bubbles in the urine – especially those that require you to flush several times before they go away—indicate protein in the urine. This foam may look like the foam you see when scrambling eggs, as the common protein found in urine, albumin, is the same protein that is found in eggs. 7. Persistent puffiness around eyes Protein in the urine is an early sign that the kidneys’ filters have been damaged, allowing protein to leak into the urine. This puffiness around your eyes can be due to the fact that your kidneys are leaking a large amount of protein in the urine, rather than keeping it in the body. 8. Swollen ankles and feet Decreased kidney function can lead to sodium (salt) retention, causing swelling in your feet and ankles. Swelling in the lower extremities can also be a sign of heart disease, liver disease and chronic leg vein problems. Learn more about salt and kidney disease .   One day, no one’s life will be lost to kidney disease. Extraordinary progress is made possible by YOU. Your gift today will help revolutionize kidney health and transform lives for the next 75 years and beyond by helping to: Equip patients and families with knowledge, resources, and access to high-quality care. Advocate for policies that address disparities and prioritize kidney health for all. Fund research and technology to advance early detection, improve treatment, and expand transplant access. This content is provided for informational use only and is not intended as medical advice or as a substitute for the medical advice of a healthcare professional. © 2026 National Kidney Foundation, Inc.
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[Skip to main content](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease#main-content) [![Home](https://www.kidney.org/sites/default/files/logo_75.svg)](https://www.kidney.org/) - [Clear All](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) Search - [Member Login](https://nationalkidneyfoundation.wildapricot.org/sys/login) - [Recursos en Español](https://www.kidney.org/es/recursos-en-espanol) Donate *** ## NKF Mega Menu - [Kidney Health](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ![](https://www.kidney.org/themes/custom/nephron/src/images/Chevron.svg) #### ![](https://www.kidney.org/themes/custom/nephron/src/images/cross.svg) - [Kidney Health](https://www.kidney.org/kidney-health) - [Kidney Topics](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [News & Stories](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Assess Your Kidney Health](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Diet & Nutrition](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ## Featured Topics - [Chronic Kidney Disease (CKD)](https://www.kidney.org/kidney-topics/chronic-kidney-disease-ckd) - [Estimated Glomerular Filtration Rate (eGFR)](https://www.kidney.org/kidney-topics/estimated-glomerular-filtration-rate-egfr) - [Stages of Chronic Kidney Disease (CKD)](https://www.kidney.org/kidney-topics/stages-chronic-kidney-disease-ckd) - [Tests to Check Your Kidney Health](https://www.kidney.org/kidney-topics/tests-to-check-your-kidney-health) - [Understanding Your Lab Values and Other CKD Health Numbers](https://www.kidney.org/kidney-topics/understanding-your-lab-values-and-other-ckd-health-numbers) [See All Kidney Topics](https://www.kidney.org/kidney-topics) ## Browse By Category - [Diet and nutrition](https://www.kidney.org/kidney-topics?f%5B0%5D=category%3A52493) - [Diseases and conditions](https://www.kidney.org/kidney-topics?f%5B0%5D=category%3A52545) - [Prevention, daily life, and wellbeing](https://www.kidney.org/kidney-topics?f%5B0%5D=category%3A52433) - [Tests and procedures](https://www.kidney.org/kidney-topics?f%5B0%5D=category%3A52586) - [Treatments and therapies](https://www.kidney.org/kidney-topics?f%5B0%5D=category%3A52589) [Image ![Hot Topics](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-05/%F0%9F%8E%9B%20Fixed%20Aspect%20Ratio%20Spacer%20%28Variants%29.png?h=38c6aecc&itok=oGl8M5sR) Hot topics in kidney health podcast Tune in for the latest research and perspectives on kidney health from NKF.](https://www.kidney.org/podcasts/hot-topics-kidney-health) Related News & Stories [Actor Erròn Jay’s Kidney Transplant and His Mission to Inspire Living Donors](https://www.kidney.org/news-stories/actor-erron-jay-s-kidney-transplant-and-his-mission-to-inspire-living-donors) [Pig Kidney Transplants in Humans: Xenotransplantation Explained by Experts](https://www.kidney.org/news-stories/pig-kidney-transplants-humans-xenotransplantation-explained-experts) [Two Kidney Xenotransplant Recipients Share What It Was Like to Make History](https://www.kidney.org/news-stories/two-kidney-xenotransplant-patient-stories) [Voices Heard: Recapping the 2026 Kidney Patient Summit](https://www.kidney.org/news-stories/voices-heard-recapping-2026-kidney-patient-summit) [See All News & Stories](https://www.kidney.org/news-listing) ## Browse By Type - 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Find a dietitian in your area.](https://sites.google.com/view/ckdrd/home?pli=1) [Image ![Woman taking a bite out of a sandwich in a restaurant](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/AdobeStock_204119487%20%281%29.jpeg?h=624f4a52&itok=aS63uva_) Nutrition Your home for resources on eating with kidney disease or to care for your overall kidney health.](https://www.kidney.org/nutrition) - [Treatment & Support](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ![](https://www.kidney.org/themes/custom/nephron/src/images/Chevron.svg) #### ![](https://www.kidney.org/themes/custom/nephron/src/images/cross.svg) - [Treatment & Support](https://www.kidney.org/treatment-support) - [Dialysis](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Transplant](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Clinical trials](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Healthcare Resources](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Wellness](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Community Connection](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ## Featured Topics - [Dialysis](https://www.kidney.org/kidney-topics/dialysis) - [Hemodialysis](https://www.kidney.org/kidney-topics/hemodialysis) - [Peritoneal Dialysis](https://www.kidney.org/kidney-topics/peritoneal-dialysis) - [Home Dialysis](https://www.kidney.org/treatment-support/dialysis/home-dialysis) - [Coping Effectively](https://www.kidney.org/kidney-topics/coping-effectively-guide-patients-and-their-families) [See all Dialysis Topics](https://www.kidney.org/kidney-topics?search=Dialysis&items_per_page=10&sort_bef_combine=search_api_relevance_DESC) Related News & Stories [Study Sheds Light on Transportation Barriers in Dialysis and Why Patient Voices Matter](https://www.kidney.org/news-stories/study-sheds-light-transportation-barriers-dialysis-and-why-patient-voices-matter) [From World Traveler to Dialysis Chair: Lessons in Not Giving Up](https://www.kidney.org/news-stories/world-traveler-to-dialysis-chair-lessons-not-giving) [How the Ransome Family Is Raising Awareness about Childhood Kidney Disease](https://www.kidney.org/news-stories/how-ransome-family-raising-awareness-about-childhood-kidney-disease) [Strength in Sharing: “There’s Power in Telling Your Kidney Story.”](https://www.kidney.org/news-stories/strength-sharing-there-s-power-telling-your-kidney-story) [See All News & Stories](https://www.kidney.org/news-listing) [Image ![woman speaking on the phone and looking off into the distance](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/beautiful-business-woman-at-the-airport-leaving-on-2023-11-27-05-16-18-utc_0.jpg?h=cb2e5c5a&itok=BaOFry84) Do you need support? NKF PEERS is a program where kidney patients, living donors, or care partners can connect over the phone with a trained mentor.](https://www.kidney.org/treatment-support/peers) ## Featured Topics - [Kidney Transplant](https://www.kidney.org/kidney-topics/kidney-transplant) - [Kidney Xenotransplantation](https://www.kidney.org/kidney-topics/xenotransplantation) - [The Kidney Transplant Waitlist](https://www.kidney.org/kidney-topics/kidney-transplant-waitlist) - [Life with a Kidney Transplant](https://www.kidney.org/kidney-topics/life-kidney-transplant) [See all Transplant Topics](https://www.kidney.org/kidney-topics?search=transplant&items_per_page=10&sort_bef_combine=search_api_relevance_DESC) Related News & Stories [Actor Erròn Jay’s Kidney Transplant and His Mission to Inspire Living Donors](https://www.kidney.org/news-stories/actor-erron-jay-s-kidney-transplant-and-his-mission-to-inspire-living-donors) [Award-Winning Director Turns Kidney Failure Battle into a Mission for Awareness](https://www.kidney.org/news-stories/award-winning-director-turns-kidney-failure-battle-mission-awareness) [He Needed a Kidney. She Answered an Email and Changed His Life Forever](https://www.kidney.org/news-stories/he-needed-kidney-she-answered-email-and-changed-his-life-forever) [Florida Scuba Diver Instructor Donates A Kidney to a Child He’d Never Met](https://www.kidney.org/news-stories/florida-scuba-diver-instructor-donates-kidney-to-child-he-d-never-met) [See All News & Stories](https://www.kidney.org/news-listing) [Image ![Kidney Donor and recipient posing in the hospital together post-transplant](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/129340667_10158967486409106_3652961820004979642_n-%281%29-%282%29.jpg?h=3e4c1220&itok=9NNDc57w) Kidney Transplantation Resources Considering a kidney transplant? We’ll help you get started.](https://www.kidney.org/transplantation) ## Featured Topics - [Clinical Trials](https://www.kidney.org/treatment-support/clinical-trials) - [Are Clinical Trials Safe?](https://www.kidney.org/kidney-topics/are-clinical-trials-safe) - [Finding out More about Clinical Trials](https://www.kidney.org/kidney-topics/finding-more-information-about-clinical-trials) - [Kidney Disease Clinical Trial Directory](https://www.kidney.org/kidney-topics/kidney-diseases-clinical-trial-directory) - [Who Can Participate in a Clinical Trial](https://www.kidney.org/kidney-topics/who-can-participate-clinical-trial) [See all Clinical Trial Topics](https://www.kidney.org/kidney-topics?search=clinical%20trials&items_per_page=10&sort_bef_combine=search_api_relevance_DESC) Related News & Stories [What You Should Know About Complement 3 Glomerulopathy (C3G)](https://www.kidney.org/news-stories/what-you-should-know-about-complement-3-glomerulopathy-c3g) [Clinical Trials for Pig-to-Human Kidney Transplantation Are Here](https://www.kidney.org/news-stories/clinical-trials-pig-to-human-kidney-transplantation-are-here) [Basic Science, Clinical Research, and Kidney Disease Treatments](https://www.kidney.org/news-stories/basic-science-clinical-research-and-kidney-disease-treatments) [Kidney Disease Clinical Trials: Are They Right for You?](https://www.kidney.org/news-stories/kidney-disease-clinical-trials-are-they-right-you) [See All News & Stories](https://www.kidney.org/news-listing) [Image ![Survey icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-41.svg) Join the KidneyCARE Study Advance kidney research by sharing your experience living with kidney disease.](https://www.kidney.org/treatment-support/kidneycare-study) [Image ![Questionnaire icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-40.svg) Impact Patient-Centered Research Kidney Research Connect matches you with research projects based on your connection to kidney disease.](https://research-connect.kidney.org/) [Image ![Man sitting at a table looking something up on his laptop](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/happy-black-male-university-student-studying-at-ho-2023-11-27-05-23-48-utc-%281%29.jpg?h=4ff9487b&itok=EhI-injh) Insurance Insurance doesn’t have to be overwhelming. Learn about insurance options and choosing a plan that is right for you.](https://www.kidney.org/subject/health-insurance) [Image ![Two seniors taking a walk together](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/senior-couple-taking-a-walk-along-the-running-trac-2023-11-27-04-52-01-utc_0.jpg?h=73306683&itok=tG-fJl-W) Coping and Self-care Implementing coping strategies and practicing self-care are essential components in effectively managing illness and promoting overall health and well-being.](https://www.kidney.org/subject/mental-health-and-wellness) [Image ![Nurse putting a bandaid on a woman's arm post-vaccine](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/senior-woman-nurse-and-plaster-for-arm-vaccine-m-2023-11-27-05-06-04-utc-%281%29.jpg?h=def3cf70&itok=7WfTWydh) Vaccine Information As a dialysis patient or transplant recipient you may be wondering — are vaccines safe for me? Do I need them?](https://www.kidney.org/subject/vaccination) [Image ![Woman taking a bite out of a sandwich in a restaurant](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/AdobeStock_204119487-%281%29.jpg?h=def3cf70&itok=dFxNlk96) Nutrition Learn about a kidney-friendly diet, so you can stay healthy with kidney disease whether you are at home or dining out.](https://www.kidney.org/nutrition-old-nov-25) [Image ![Group of women doing tai chi in the park](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/StockPhoto_k-%281%29.jpg?h=def3cf70&itok=XekZBZct) Exercise Exercise is important for everyone, especially for people with kidney disease.](https://www.kidney.org/subject/exercise-and-physical-activity) [Image ![Older couple cuddling outside](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/StockPhoto_b-%281%29.jpg?h=6b305570&itok=JSqu4Cik) Sexual Health Kidney disease can affect your sexuality in many ways — from hormones, nerves, energy levels, even medicine.](https://www.kidney.org/subject/sexual-health-and-intimacy) [Image ![Phone call icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-28.svg) NKF Cares Offering support for people affected by kidney disease, organ donation, or transplantation.](https://www.kidney.org/nkfcares) [Image ![Calendar icon, zooming in on one day](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-29.svg) Local and National Events Attend a National Kidney Foundation event close to you.](https://www.kidney.org/events) [Image ![Two people reaching out to each other icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-30.svg) NKF Peers Where kidney patients are connected with trained mentors who have been there themselves.](https://www.kidney.org/treatment-support/peers) [Image ![Megaphone icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-42.svg) Become a Patient Advocate Add your voice to Voices for Kidney Health.](https://www.kidney.org/take-action/advocate/advocate-resources) [Image ![Laptop showing chat bubbles icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-32.svg) Online Communities Where patients and caregivers can share experiences, ask questions, and get answers.](https://www.kidney.org/treatment-support/communities) [Image ![Chat bubble with a story inside icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-33.svg) Patient Stories Read empowering stories from patients and their loved ones.](https://www.kidney.org/news-stories?f%5B0%5D=type%3A52732) - [Transplantation](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ![](https://www.kidney.org/themes/custom/nephron/src/images/Chevron.svg) #### ![](https://www.kidney.org/themes/custom/nephron/src/images/cross.svg) - [Transplantation](https://www.kidney.org/transplantation) - [Receiving a Kidney Transplant](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Donating a Kidney](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ## Featured Topics - [Kidney Transplant](https://www.kidney.org/kidney-topics/kidney-transplant) - [The Kidney Transplant Waitlist](https://www.kidney.org/kidney-topics/kidney-transplant-waitlist) - [Getting a Kidney Transplant](https://www.kidney.org/kidney-topics/getting-kidney-transplant) - [Getting a Living Donor Kidney Transplant](https://www.kidney.org/kidney-topics/getting-living-donor-kidney-transplant) - [Life with a Kidney Transplant](https://www.kidney.org/kidney-topics/life-kidney-transplant) [See all Transplantation Topics](https://www.kidney.org/kidney-topics?search=transplantation&items_per_page=10&sort_bef_combine=search_api_relevance_DESC) [Image ![kidney transplant icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-36.svg) Find a Transplant Workshop Join us at a live event near you to learn more with The Big Ask, The Big Give.](https://www.kidney.org/transplantation/live-events) [Image ![medical record on a clipboard icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-35.svg) Learn More About Kidney Transplant Dive deep with videos and patient stories in the Kidney Learning Center.](https://kidney.instilled.com/player/medium/3120007902769714975?_gl=1*1xkn3at*_gcl_au*MTAwNzA4ODI4NC4xNzYxNjY5ODY1&embed=true&layout=fullscreen&overlay=false) [Image ![A kidney donor and a kidney recipient posing together at a Kidney Walk](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/clip-gny-group--no-sign-DSC06784-copy-%282%29.jpg?h=6b305570&itok=Z5Zy5d8q) Resources & Get Involved Get connected for support on your transplant journey.](https://www.kidney.org/transplantation#resources) ## Featured Topics - [Becoming a Living Donor](https://www.kidney.org/kidney-topics/becoming-living-donor) - [Making the Decision to Donate](https://www.kidney.org/transplantation/making-decision-to-donate) - [Living Kidney Donor Evaluation](https://www.kidney.org/node/24335) - [Living Donor Finances and Insurance](https://www.kidney.org/transplantation/financial-and-insurance-issues) - [What to Expect After Donation](https://www.kidney.org/transplantation/what-to-expect-after-donation) [See all Kidney Donation Topics](https://www.kidney.org/kidney-topics?search=kidney%20donation&items_per_page=10&sort_bef_combine=search_api_relevance_DESC) [Image ![kidney transplant icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-36.svg) Learn More About Living Donation Dive deep with videos and donor stories in the Kidney Learning Center.](https://learningcenter.kidney.org/spa/courses/resource/becoming-a-living-donor/curriculum/home/default) [Image ![medical center icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-38.svg) Ready to take the next step? Get started with information on how to connect with a transplant center.](https://www.kidney.org/transplantation/how-to-donate) [Image ![Kidney walk participant wearing a Hero badge](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2024-07/walk_nkfnyc2015-307_B-%284%29.jpg?h=2075fdba&itok=LeJn4DaO) Resources & Get Involved Get connected with others who have donated a kidney.](https://www.kidney.org/transplantation#resources) - [For Professionals](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ![](https://www.kidney.org/themes/custom/nephron/src/images/Chevron.svg) #### ![](https://www.kidney.org/themes/custom/nephron/src/images/cross.svg) - [For Professionals](https://www.kidney.org/professionals) - [Professional Membership](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Continuing Education](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Research](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [CKDintercept](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Kidney Disease Outcomes Quality Initiative (KDOQI)](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Clinical Tools](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) [Image ![membership id card icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-16.svg) Become a Member Learn more about all the benefits a NKF membership can provide.](https://www.kidney.org/professionals/membership) [Image ![Star badge icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-20.svg) Fellowship of the National Kidney Foundation FNKF recognizes professionals for service to NKF.](https://www.kidney.org/professionals/membership/fellowship) [Image ![Lock and key icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-18.svg) Member Login We are multidisciplinary. We are clinicians and researchers. We are advocates.](https://nationalkidneyfoundation.wildapricot.org/sys/login) [Image ![award badge icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-19.svg) NSW-C The first national credentialed classification for nephrology social work.](https://www.kidney.org/professionals/membership/nsw-c) [Image ![medical journals on a shelf](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-17.svg) Access to NKF Journals NKF's journals feature the latest research in clinical nephology.](https://www.kidney.org/professionals/journals) [Image ![People sitting at a meeting table together](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-21.svg) NKF Professional Councils Representative bodies of NKF's professional membership.](https://www.kidney.org/professionals#exec-councils) [Image ![Square academic cap icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-12_0.svg) Professional Education Resource Center CME/CE courses designed for professionals committed to improving patient outcomes.](https://cme.kidney.org/spa/courses/catalog/nkf/home?_gl=1*1sv6jjj*_gcl_aw*R0NMLjE3NDQ0MDM2OTAuQ2p3S0NBanctLUtfQmhCNUVpd0F1d1lveXI2RWNFNmJQcG1EblRpNmJ4aHd4TlJQcm9Qd09ZeFVxN0U5TzY2OXZnR2V6VlY0cGtpWklCb0NieGtRQXZEX0J3RQ..*_gcl_au*MjEwMjkxODMxNi4xNzQxNzkyMjM1LjE3MzYwMDg1NTUuMTc0OTE1MDg1MS4xNzQ5MTUxMTIx) [Image ![headphones icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-13.svg) Kidney Commute Podcast Providing connection through education and serving as an innovative opportunity to fulfill CE requirements.](https://www.kidney.org/podcasts/kidney-commute) [Image ![projector screen with kidney bean icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-14.svg) Spring Clinical Meetings NKF’s premiere educational event for the interprofessional kidney health team.](https://www.kidney.org/spring-clinical) ## Funding [Image ![hand offering money icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-01.svg) Grants Access information on available grants and open applications.](https://www.kidney.org/professionals/grants) [Image ![lightbulb icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-02.svg) NKF Innovation Fund Learn about our game changing impact investment initiative.](https://www.kidney.org/professionals/innovation-fund) ## Latest Research [Image ![connections icon](https://www.kidney.org/sites/default/files/2025-07/megamenu_icons_v3-50.svg) Research Connect Find resources to connect you with patients and data for your research.](https://research-connect.kidney.org/?_gl=1*pwjsm6*_gcl_au*MjQzOTU0MDA5LjE3NTMxOTgzNTguMTM4MjAxMTYxLjE3NTM4MTM1NDEuMTc1MzgxMzYxNg..) [Image ![shelf of medical journals icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-04.svg) NKF’s Family of Journals NKF's journals feature the latest research in clinical nephrology.](https://www.kidney.org/professionals/journals) [Image ![researcher with clipboard](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-07/megamenu_istock-1350942341.jpg?h=38c6aecc&itok=DYsMd4PI) Research Access grant opportunities, KDOQI Clinical Practice Guidelines, and clinical trial information.](https://www.kidney.org/professionals/research) What is CKDintercept? A groundbreaking initiative from the National Kidney Foundation to improve chronic kidney disease (CKD) testing, recognition, and management in primary care. [Image ![medical information icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-05.svg) Learn More About CKDintercept Only 10% of people living with CKD are aware that they have CKD.](https://www.kidney.org/professionals/ckdintercept) [Image ![Medical textbook icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-06.svg) CKDintercept National Overview NKF and partners will develop local road maps to drive a cultural shift in primary care.](https://www.kidney.org/professionals/ckdintercept/overview) [Image ![Laptop with medical symbol icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-39.svg) CKD Change Package A systematic approach to transform CKD care, advance health equity, and improve health care quality.](https://www.kidney.org/professionals/ckdintercept/ckd-change-package) What is KDOQI? KDOQI (Kidney Disease Outcomes Quality Initiative) is world renowned for improving the diagnosis and treatment of kidney disease, these guidelines have changed the practices of healthcare professionals and improved thousands of lives. ## Tools & Resources - [Guidelines and Commentaries](https://www.ajkd.org/content/kdoqiguidelines) - [Guideline Development Process](https://www.kidney.org/professionals/kdoqi/guideline-development-process) - [Patient Centered Quality Measures](https://www.kidney.org/professionals/kdoqi/patient-centered-quality-measures-kidney-care) [Learn more about KDOQI](https://www.kidney.org/professionals/kdoqi) [Image ![Zoom in on checklist icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-07_0.svg) Vascular Access Guidelines And Implementation Tools Comprehensive slide decks created by interdisciplinary experts.](https://www.kidney.org/professionals/kdoqi/guidelines-and-commentaries/vascular-access) [Image ![kidney icon on a smartphone](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-08.svg) KDOQI App Download now to access guidelines and commentaries at your fingertips.](https://www.kidney.org/apps/kdoqi-app) ## Featured Tools - [CKD Heat Map](https://www.kidney.org/sites/default/files/heat_map_card.pdf) - [Kidney Disease Stages](https://www.kidney.org/sites/default/files/01-10-7278_HBG_CKD_Stages_Flyer3.pdf) - [Medium Cut-Off Dialyzers for Expanded Hemodialysis](https://www.kidney.org/sites/default/files/2025-04/742-0015_2503_medcutoffdialyzers_bulletin4.pdf) - [Phosphorus for Dialysis Patients](https://www.kidney.org/sites/default/files/01-10-7073_FBF_Phosphorus_Card2.pdf) - [CKD Change Package](https://www.kidney.org/sites/default/files/11.30.2023_622-9567_2310_ckd_changepackv10.pdf) - [The Interconnectedness of CKD, Systemic Inflammation, and ASCVD](https://www.kidney.org/professionals/tools/interconnectedness-ckd-systemic-inflammation-ascvd_old) [See all Clinician Tools](https://www.kidney.org/professionals/tools) [Image ![Calculator icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-09.svg) eGFR Calculator Use our GFR calculators to estimate GFR for adults or children.](https://www.kidney.org/professionals/kdoqi/gfr_calculator) [Image ![Toolkit icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v3_0.svg) Living Donation Business Case Toolkit Learn more about how to grow your living kidney donation program.](https://www.kidney.org/professionals/living-donation-business-case-toolkit) [Image ![kidney icon on a smartphone](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-08.svg) KDOQI App Download now to access guidelines and commentaries at your fingertips.](https://www.kidney.org/apps/kdoqi-app) [Image ![Zoom in on checklist icon](https://www.kidney.org/sites/default/files/2024-07/Megamenu_Icons_V1-07_0.svg) Vascular Access Guidelines And Implementation Tools Comprehensive slide decks created by interdisciplinary experts.](https://www.kidney.org/professionals/kdoqi/guidelines-and-commentaries/vascular-access) - [Take Action](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ![](https://www.kidney.org/themes/custom/nephron/src/images/Chevron.svg) #### ![](https://www.kidney.org/themes/custom/nephron/src/images/cross.svg) - [Take Action](https://www.kidney.org/take-action) - [Fundraising Events](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Fundraise Your Way](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Corporate Support](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Volunteer](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) [Image ![Kidney Walk participants happily walking together](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/denver14-1.jpg?h=b3660f0d&itok=VSNxGjBm) Kidney Walk Participate in NKF's Kidney Walk and fundraise to make a lasting impact for patients, families, and people at risk. Find a Walk near you.](https://www.kidneywalk.org/) [Image ![A group of four golfers walking on a golf course](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/scottcampbellphoto-650-1.jpg?h=82f92a78&itok=mLH7GXkD) NKF Golf Classic Join thousands of professionals at the Premier Amateur Golf Event for Charity — held at some of the nation's most exclusive courses. Find a tournament near you.](https://www.kidney.org/take-action/nkf-golf-classic) [Image ![A room full of people at the NKF Jazz Gala](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/nkf_jazz_gala_2018-58-1.jpg?h=82f92a78&itok=O0BUv8Nt) Social Events Attend a premier culinary event, meet the most recognizable names in literature, or honor those who help drive life-changing breakthroughs. Find an event near you.](https://www.kidney.org/get-involved/signature-events) [Image ![Three cyclists posing before a group NKF fundraising ride](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/tk-moves-get-involved-1.jpg?h=57024e64&itok=xi0ZNWDU) Create a Fundraiser Celebrate milestones or use your passions and hobbies to bring hope to the 37 million Americans battling kidney disease.](https://teamkidney.rallybound.org/) [Image ![Group of family and friends doing a community Kidney Walk in a residential neighborhood](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/attachment_cropped.jpg?h=94a5678e&itok=0HOFjeyK) Kidney Walk Your Way Kidney Walk your way is your chance to be a part of our Kidney Walk community on a date and location of your choice by doing an activity you love\!](https://www.kidneywalk.org/yourway) [Image ![Person playing a video game in their living room](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/streams-get-involved.jpg?h=82f92a78&itok=BsMKvww9) Stream for Kidney Health Join the Team Kidney Streams community to help raise important funds and awareness while livestreaming what you love.](https://tiltify.com/national-kidney-foundation) [Image ![Two professionals at an NKF event discussing business opportunities](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/crf_6407_2.jpg?h=82f92a78&itok=6c8wG4n6) Become a Corporate Partner Learn more about how your company can influence the future of kidney disease.](https://www.kidney.org/get-involved/become-a-partner) [Image ![Person signing someone up for a program with a tablet](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/join_circle_members.jpeg?h=0da486ab&itok=ZMt5toKN) Circle of Excellence An employer recognition program dedicated to eliminating barriers to living donation.](https://www.kidney.org/get-involved/circle-excellence) [Image ![Two employees brainstorming and working together happily](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-06/female-businesswoman-lady-black-white-skin-color-d-2025-03-07-02-23-41-utc_web.jpg?h=38c6aecc&itok=tPCZRsRP) Corporate Wellness Solutions A suite of tools to support organizations in advancing kidney health and overall wellbeing among their employees.](https://www.kidney.org/take-action/corporate-wellness-employers) [Image ![megaphone icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-34.svg) Be an Advocate Take action and use your voice on behalf of kidney patients with local and national government.](https://www.kidney.org/advocacy) [Image ![Hands in teamwork icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-35.svg) Volunteer Opportunities Your skills and interests can help build healthier communities, spread the word, and create real change. Find an opportunity near you.](https://www.kidney.org/get-involved/volunteer#search) - [Ways to Give](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ![](https://www.kidney.org/themes/custom/nephron/src/images/Chevron.svg) #### ![](https://www.kidney.org/themes/custom/nephron/src/images/cross.svg) - [Ways to Give](https://www.kidney.org/ways-to-give) - [Donate Online](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [Philanthropy](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) - [More Ways to Give](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) [Image ![Grandmother and granddaughter hugging and smiling](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/istock-1265315806.jpg?h=82f92a78&itok=EhREI3Hs) Become a Monthly Donor Become a Change Maker—give monthly to support critical programs in the fight against kidney disease.](https://support.kidney.org/campaign/580848/donate?utm_source=kidney.org&utm_medium=Website&utm_content=Landing&utm_campaign=Evergreen_Donation_Campaign&amount=&c_src=GetInvolvedMonthly) [Image ![woman looking happy in a hospital bed](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/stocksy_txpe437f581opt200_originaldelivery_3087613-1.jpg?h=82f92a78&itok=LIIjxc75) Donate Now Your gift today will help revolutionize kidney health and transform lives.](https://support.kidney.org/campaign/612763/donate?utm_source=kidney.org&utm_medium=Website&utm_content=GetInvolved&utm_campaign=Evergreen_Donation_Campaign&amount=&c_src=GetInvolvedDonate) [Image ![orange flower](https://www.kidney.org/sites/default/files/styles/mega_menu_image_/public/2025-05/celebrate_loved_one-3.jpeg?h=ef2d6e95&itok=TAYW7_vo) Memorial Giving Create a fundraiser in honor of your loved one.](https://kidneytribute.rallybound.org/) [Image ![living will with pen icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-26.svg) Wills, Trusts and Legacy Giving Build your legacy to support families facing kidney disease.](https://www.kidney.org/content/planned-giving) [Image ![hand holding out money with a plant coming out icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-27.svg) Donor Advised Funds (DAF) Make a flexible, tax-efficient gift through your Donor-Advised Fund (DAF).](https://www.freewill.com/daf/nkf) [Image ![taxes pie chart icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-28.svg) IRA Charitable Rollover The savviest way for you to use your IRA to maximize your impact.](https://www.freewill.com/qcd/nkf) [Image ![stocks line chart icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-29.svg) Stock Gifts Make a gift of stock.](https://www.freewill.com/smartgiving/nkf?utm_source=partner&utm_medium=website&utm_campaign=nkf_waystogivepg&product=STOCK_GIFT) [Image ![phone icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v1-28.svg) Donate by Mail or Phone Use our mail-in donation form to send your offline donation to NKF.](https://www.kidney.org/sites/default/files/023-9761_2404_donationform_final.pdf) [Image ![car icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-30.svg) Donate Your Car Donate your old car, boat or tractor to help improve the lives of the millions,](https://www.kidney.org/support/kidneycars/) [Image ![house icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-31.svg) Donate Real Estate Fight kidney disease with a gift of property.](https://kidney.careasy.org/real-estate-donation) [Image ![Hand holding out cryptocurrency](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-32.svg) Donate Crypto More ways to fund our work while providing you with extra tax benefits.](https://www.freewill.com/smartgiving/nkf?utm_source=partner&utm_medium=website&utm_campaign=nkf_waystogivepg&product=CRYPTO) [Image ![puzzle pieces fitting together icon](https://www.kidney.org/sites/default/files/2025-05/megamenu_icons_v2-33.svg) Match Your Donation Double, or even triple, your donation with a matching gift from your employer.](https://www.kidney.org/matchinggifts) - [About NKF](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease) ![](https://www.kidney.org/themes/custom/nephron/src/images/Chevron.svg) #### ![](https://www.kidney.org/themes/custom/nephron/src/images/cross.svg) - [About NKF](https://www.kidney.org/about) - [Diversity, Equity, Inclusion](https://www.kidney.org/about/diversity-equity-inclusion) - [Press Room](https://www.kidney.org/pressroom) - [Kidney Equity for All](https://www.kidney.org/about/kidney-equity-for-all) - [Careers](https://www.kidney.org/about/careers) - [NKF Leadership](https://www.kidney.org/about/leadership) - [Contact Us](https://www.kidney.org/about/contact-us) - [Local Offices](https://www.kidney.org/offices) - [Kidney Disease: Fact Sheet](https://www.kidney.org/about/kidney-disease-fact-sheet) ## Breadcrumb 1. [Home](https://www.kidney.org/) 2. [News and Stories](https://www.kidney.org/news-stories) 3. 10 Signs You May Have Kidney Disease # 10 Signs You May Have Kidney Disease Back to Top [Diseases and conditions](https://www.kidney.org/subject/diseases-and-conditions) [Signs and symptoms](https://www.kidney.org/subject/signs-and-symptoms) December 17, 2020 ![signs\_of\_kidney\_disease.png](https://www.kidney.org/sites/default/files/signs_of_kidney_disease.png) An estimated 35.5 million U.S. adults have kidney disease. Most don’t know they have it. While the only way to know if you have kidney disease is to get tested, there are signs to watch for. ### Table of Contents - [Kidney Disease Risk Factors](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease#kidney-disease-risk-factors "Kidney Disease Risk Factors") - [Kidney Disease Testing](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease#kidney-disease-testing "Kidney Disease Testing") - [10 Signs of Kidney Disease](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease#10-signs-kidney-disease "10 Signs of Kidney Disease") ## Kidney Disease Risk Factors If you’re at risk for kidney disease due to [high blood pressure](https://www.kidney.org/kidney-health/high-blood-pressure?utm_source=organic&utm_medium=blog&utm_campaign=10-signs), [diabetes](https://www.kidney.org/kidney-health/diabetes?utm_source=organic&utm_medium=blog&utm_campaign=10-signs), a family history of kidney failure, or if you’re older than age 60, it’s important to get tested annually for kidney disease. “There are a number of physical signs of kidney disease, but sometimes people attribute them to other conditions,” said Dr. Joseph Vassalotti, Chief Medical Officer at the NKF. “Those with kidney disease tend not to experience symptoms until the very late stages, when the kidneys are failing or when there are large amounts of protein in the urine. This is one of the reasons why only 10% of people with chronic kidney disease know that they have it.” Are you at risk of kidney disease? [Take this one-minute quiz to find out](https://www.kidney.org/kidney-quiz/?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ## Kidney Disease Testing Two easy tests help determine if you have kidney disease or not; - [Estimated glomerular filtration rate (eGFR)](https://www.kidney.org/kidney-topics/estimated-glomerular-filtration-rate-egfr?utm_source=organic&utm_medium=blog&utm_campaign=10-signs): Blood test that estimates how well the kidneys function. - [Urine albumin-creatinine ratio (uACR)](https://www.kidney.org/kidney-topics/urine-albumin-creatinine-ratio-uacr?utm_source=organic&utm_medium=blog&utm_campaign=10-signs): Urine test that measures albumin (a protein) and creatinine, a waste product. [Learn more about kidney disease testing](https://www.kidney.org/news-stories/kidney-health-101-making-sense-kidney-tests-and-lab-results?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ![](https://www.kidney.org/sites/default/files/2024-08/441-9819_2407_PatientJourney_Social6.jpg) ## Your kidney health is unique. Your path should be too. [Get Started](https://kidney.org/ckd-journey) ## 10 Signs of Kidney Disease ### 1\. Less Energy or Trouble Concentrating A severe decrease in kidney function can lead to a buildup of toxins and impurities in the blood. This can cause people to feel tired or weak and can make it hard to concentrate. Another complication of kidney disease is anemia, which can cause weakness and fatigue. [Learn more about anemia](https://www.kidney.org/kidney-topics/anemia-and-chronic-kidney-disease?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ### **2\. Trouble sleeping** When the kidneys aren't filtering properly, toxins stay in the blood rather than leaving the body through the urine. This can make it difficult to sleep. There is also a link between [obesity](https://www.kidney.org/kidney-topics/overweight-obesity?utm_source=organic&utm_medium=blog&utm_campaign=10-signs) and chronic kidney disease, and sleep apnea is more common in those with kidney disease, compared with the general population. ### **3\. Dry and itchy skin** Healthy kidneys do many important jobs. They remove wastes and extra fluid from your body, help make red blood cells, keep bones strong, and work to maintain the right amount of minerals in your blood. Dry and itchy skin can be a sign of the mineral and bone disease that often accompanies advanced kidney disease, or when the kidneys are no longer able to keep the right balance of minerals and nutrients in your blood. [Learn more about itchy skin and kidney disease](https://www.kidney.org/news-stories/itching-and-kidney-disease?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ## Join the NKF Blog Newsletter Get inspirational stories and kidney disease resources delivered to your inbox every month. You'll gain practical insights and expert advice to help you better understand and manage your kidney health no matter where you are on your kidney journey. Subscribe today. ### 4\. Urinating more frequently If you feel the need to urinate more often, especially at night, this can be a sign of kidney disease. When the kidney's filters are damaged, it can cause an increase in the urge to urinate. Sometimes this can also be a sign of a urinary infection or enlarged prostate in men. ### 5\. Blood in urine Healthy kidneys typically keep the blood cells in the body when filtering wastes from the blood to create urine, but when the kidney's filters have been damaged, these blood cells can start to "leak" out into the urine. In addition to signaling kidney disease, blood in the urine can be indicative of tumors, kidney stones, or an infection. [Learn more about blood in urine](https://www.kidney.org/kidney-topics/hematuria-adults?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ### 6\. Foamy urine Excessive bubbles in the urine – especially those that require you to flush several times before they go away—indicate protein in the urine. This foam may look like the foam you see when scrambling eggs, as the common protein found in urine, albumin, is the same protein that is found in eggs. ### 7\. Persistent puffiness around eyes Protein in the urine is an early sign that the kidneys’ filters have been damaged, allowing protein to leak into the urine. This puffiness around your eyes can be due to the fact that your kidneys are leaking a large amount of protein in the urine, rather than keeping it in the body. ### 8\. Swollen ankles and feet Decreased kidney function can lead to sodium (salt) retention, causing swelling in your feet and ankles. Swelling in the lower extremities can also be a sign of heart disease, liver disease and chronic leg vein problems. [Learn more about salt and kidney disease](https://www.kidney.org/kidney-topics/sodium-and-your-ckd-diet-how-to-spice-your-cooking?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ## One day, no one’s life will be lost to kidney disease. Extraordinary progress is made possible by YOU. Your gift today will help revolutionize kidney health and transform lives for the next 75 years and beyond by helping to: - Equip patients and families with knowledge, resources, and access to high-quality care. - Advocate for policies that address disparities and prioritize kidney health for all. - Fund research and technology to advance early detection, improve treatment, and expand transplant access. ### **9\. Poor appetite** This is a very general symptom, but a buildup of toxins resulting from reduced kidney function can be one of the causes. [Find kidney-friendly nutrition tips and recipes](https://www.kidney.org/nutrition?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ### **10\. Muscle cramping** Electrolyte imbalances can result from impaired kidney function. For example, low calcium levels and poorly controlled phosphorus may contribute to muscle cramping. [Learn more about balancing the body's pH](https://www.kidney.org/news-stories/balancing-body-s-ph-what-you-need-to-know-about-metabolic-acidosis?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). This content is provided for informational use only and is not intended as medical advice or as a substitute for the medical advice of a healthcare professional. © 2026 National Kidney Foundation, Inc. ## Kidney Topics [Hyponatremia (low sodium level in the blood) Diseases and conditions, Hyponatremia](https://www.kidney.org/kidney-topics/hyponatremia-low-sodium-level-blood) [Diabetes and Kidney Disease (Stages 1-4) Diseases and conditions, Kidney diseases and conditions, Diabetes, Early stage kidney disease](https://www.kidney.org/kidney-topics/diabetes-and-kidney-disease-stages-1-4) [What Is Dry Weight? Treatments and therapies, Diseases and conditions, Dialysis, Signs and symptoms, Hemodialysis, Fluid overload and edema](https://www.kidney.org/kidney-topics/what-dry-weight) [Stage 3a Chronic Kidney Disease (CKD) Diseases and conditions, Kidney diseases and conditions, Early stage kidney disease](https://www.kidney.org/kidney-topics/stage-3a-chronic-kidney-disease-ckd) [Kidney Stones Diseases and conditions, Kidney diseases and conditions, Kidney stones](https://www.kidney.org/kidney-topics/kidney-stones) [6-Step Guide to Protecting Kidney Health Diseases and conditions, Kidney diseases and conditions, Chronic kidney disease](https://www.kidney.org/kidney-topics/6-step-guide-to-protecting-kidney-health) #### Pagination - [next](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease?page=1 "next") [See More Kidney Topics](https://www.kidney.org/kidney-topics) ## News and Stories [![2006 Kidney Walk with Banner NKF "Walk Starts" ](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/2025-07/kidney-walk-2000s.png?itok=Bk4ROYeH) July 31, 2025 News Events & Fundraising How NKF Got Here: Kidney Care in the 2000s](https://www.kidney.org/news-stories/how-nkf-got-here-kidney-care-2000s) [![Winner of Transplant Games holding their trophy ](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/2025-06/1990s-milestones.png?itok=sBUMfbI7) June 05, 2025 News Events & Fundraising How NKF Got Here: Kidney Care in the 1990s](https://www.kidney.org/news-stories/how-nkf-got-here-kidney-care-1990s) [![](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/ada_and_harry_debold_660_0.jpg?itok=3FUmpk2A) May 03, 2017 Patient Stories Ada DeBold: How One Mother’s Love Saved Thousands of Lives](https://www.kidney.org/news-stories/ada-debold-how-one-mother-s-love-saved-thousands-lives) [![Patient with a doctor - checking the body's pH](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/2024-08/Balancing%20the%20Body%27s%20pH.png?itok=4WRGhNgf) August 29, 2024 Patient Education Balancing the Body's pH: What You Need to Know About Metabolic Acidosis](https://www.kidney.org/news-stories/balancing-body-s-ph-what-you-need-to-know-about-metabolic-acidosis) [![melissa.png](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/melissa.png?itok=WQ9OU5Ix) February 16, 2023 Advocacy Patient Stories A Shocking Kidney Disease Diagnosis Leads to a Lifetime of Advocacy](https://www.kidney.org/news-stories/shocking-kidney-disease-diagnosis-leads-to-lifetime-advocacy) [![Two seniors taking a walk together](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/2024-07/senior-couple-taking-a-walk-along-the-running-trac-2023-11-27-04-52-01-utc_0.jpg?itok=MWy7kG5G) January 27, 2016 Prevention & Awareness 7 Tips to Protect Your Kidney & Heart Health](https://www.kidney.org/news-stories/7-tips-to-protect-your-kidney-heart-health) #### Pagination - [next](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease?page=1 "next") [See More News and Stories](https://www.kidney.org/news-stories) ## Recipes [![Creamy Curry Rice and Apple Salad](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/images/curry.jpg?itok=fE7RZfUo) Creamy Curry Rice & Apple Salad 1 hour](https://www.kidney.org/nutrition/recipes/creamy-curry-rice-apple-salad) [![Chicken Pad Thai](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/images/pad-thai_320px.jpg?itok=G45QaJBr) Chicken Pad Thai 1 hour 25 minutes](https://www.kidney.org/nutrition/recipes/chicken-pad-thai) [![Avocado Salad, Have a Plant logo](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/2025-12/avocado-garden-salad_istock-512687520_logo_v2.jpg?itok=8Kfx19xZ) Avocado Garden Salad 20 minutes](https://www.kidney.org/nutrition/recipes/avocado-garden-salad) [![Fruit Crisp](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/fruit_crisp.jpg?itok=ziVu5tbp) Fruit Crisp 1 hour](https://www.kidney.org/nutrition/recipes/fruit-crisp) [![Greek salad with orzo, tomatoes, cucumbers, feta, chickpeas, and olives](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/2025-12/greek_orzo_salad_web.jpg?itok=Pk0OpAZ8) Greek Orzo Salad 20 minutes](https://www.kidney.org/nutrition/recipes/greek-orzo-salad) [![Italian Basil Chicken Sliders](https://www.kidney.org/sites/default/files/styles/news_listing_card_image_style/public/italian_basil_chicken_sliders.jpg?itok=aspDpxsR) Italian Basil Chicken Sliders 1 hour](https://www.kidney.org/nutrition/recipes/italian-basil-chicken-sliders) #### Pagination - [next](https://www.kidney.org/news-stories/10-signs-you-may-have-kidney-disease?page=1 "next") [See More Recipes](https://www.kidney.org/nutrition/recipes) ## Quick Links - [About Us](https://www.kidney.org/about) - [Careers](https://www.kidney.org/about/careers) - [Contact Us](https://www.kidney.org/about/contact) - [National Partners](https://www.kidney.org/partners) - [Our Store](https://nkf.worksmartsuite.com/UserContentStart.aspx) - [Press Room](https://www.kidney.org/press-room) - [Recursos en Español](https://www.kidney.org/es/spanish-resources) ## Connect with Us ## Get emails from NKF #### Give to NKF Contribute to our mission with a general, memorial, or honor donation. 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Readable Markdown
December 17, 2020 ![signs\_of\_kidney\_disease.png](https://www.kidney.org/sites/default/files/signs_of_kidney_disease.png) An estimated 35.5 million U.S. adults have kidney disease. Most don’t know they have it. While the only way to know if you have kidney disease is to get tested, there are signs to watch for. ## Kidney Disease Risk Factors If you’re at risk for kidney disease due to [high blood pressure](https://www.kidney.org/kidney-health/high-blood-pressure?utm_source=organic&utm_medium=blog&utm_campaign=10-signs), [diabetes](https://www.kidney.org/kidney-health/diabetes?utm_source=organic&utm_medium=blog&utm_campaign=10-signs), a family history of kidney failure, or if you’re older than age 60, it’s important to get tested annually for kidney disease. “There are a number of physical signs of kidney disease, but sometimes people attribute them to other conditions,” said Dr. Joseph Vassalotti, Chief Medical Officer at the NKF. “Those with kidney disease tend not to experience symptoms until the very late stages, when the kidneys are failing or when there are large amounts of protein in the urine. This is one of the reasons why only 10% of people with chronic kidney disease know that they have it.” Are you at risk of kidney disease? [Take this one-minute quiz to find out](https://www.kidney.org/kidney-quiz/?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ## Kidney Disease Testing ### 1\. Less Energy or Trouble Concentrating A severe decrease in kidney function can lead to a buildup of toxins and impurities in the blood. This can cause people to feel tired or weak and can make it hard to concentrate. Another complication of kidney disease is anemia, which can cause weakness and fatigue. [Learn more about anemia](https://www.kidney.org/kidney-topics/anemia-and-chronic-kidney-disease?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ### **2\. Trouble sleeping** When the kidneys aren't filtering properly, toxins stay in the blood rather than leaving the body through the urine. This can make it difficult to sleep. There is also a link between [obesity](https://www.kidney.org/kidney-topics/overweight-obesity?utm_source=organic&utm_medium=blog&utm_campaign=10-signs) and chronic kidney disease, and sleep apnea is more common in those with kidney disease, compared with the general population. ### **3\. Dry and itchy skin** Healthy kidneys do many important jobs. They remove wastes and extra fluid from your body, help make red blood cells, keep bones strong, and work to maintain the right amount of minerals in your blood. Dry and itchy skin can be a sign of the mineral and bone disease that often accompanies advanced kidney disease, or when the kidneys are no longer able to keep the right balance of minerals and nutrients in your blood. [Learn more about itchy skin and kidney disease](https://www.kidney.org/news-stories/itching-and-kidney-disease?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ## Join the NKF Blog Newsletter Get inspirational stories and kidney disease resources delivered to your inbox every month. You'll gain practical insights and expert advice to help you better understand and manage your kidney health no matter where you are on your kidney journey. Subscribe today. ### 4\. Urinating more frequently If you feel the need to urinate more often, especially at night, this can be a sign of kidney disease. When the kidney's filters are damaged, it can cause an increase in the urge to urinate. Sometimes this can also be a sign of a urinary infection or enlarged prostate in men. ### 5\. Blood in urine Healthy kidneys typically keep the blood cells in the body when filtering wastes from the blood to create urine, but when the kidney's filters have been damaged, these blood cells can start to "leak" out into the urine. In addition to signaling kidney disease, blood in the urine can be indicative of tumors, kidney stones, or an infection. [Learn more about blood in urine](https://www.kidney.org/kidney-topics/hematuria-adults?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ### 6\. Foamy urine Excessive bubbles in the urine – especially those that require you to flush several times before they go away—indicate protein in the urine. This foam may look like the foam you see when scrambling eggs, as the common protein found in urine, albumin, is the same protein that is found in eggs. ### 7\. Persistent puffiness around eyes Protein in the urine is an early sign that the kidneys’ filters have been damaged, allowing protein to leak into the urine. This puffiness around your eyes can be due to the fact that your kidneys are leaking a large amount of protein in the urine, rather than keeping it in the body. ### 8\. Swollen ankles and feet Decreased kidney function can lead to sodium (salt) retention, causing swelling in your feet and ankles. Swelling in the lower extremities can also be a sign of heart disease, liver disease and chronic leg vein problems. [Learn more about salt and kidney disease](https://www.kidney.org/kidney-topics/sodium-and-your-ckd-diet-how-to-spice-your-cooking?utm_source=organic&utm_medium=blog&utm_campaign=10-signs). ## One day, no one’s life will be lost to kidney disease. Extraordinary progress is made possible by YOU. Your gift today will help revolutionize kidney health and transform lives for the next 75 years and beyond by helping to: - Equip patients and families with knowledge, resources, and access to high-quality care. - Advocate for policies that address disparities and prioritize kidney health for all. - Fund research and technology to advance early detection, improve treatment, and expand transplant access. This content is provided for informational use only and is not intended as medical advice or as a substitute for the medical advice of a healthcare professional. © 2026 National Kidney Foundation, Inc.
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