🕷️ Crawler Inspector

URL Lookup

Direct Parameter Lookup

Raw Queries and Responses

1. Shard Calculation

Query:

Response:

Calculated Shard: 98 (from laksa005)

2. Crawled Status Check

Query:

curl -X POST \
  'http://laksa098.int.ahrefs:8124/' \
  -H 'Content-Type: text/plain' \
  -H 'X-ClickHouse-Database: crawler3' \
  -H 'Authorization: Basic YXBpOg==' \
  -d 'SELECT getAhrefsURLFromUnparsed(src_unparsed) AS found_url, ifNull(toUnixTimestamp(download_stamp), 0) AS crawl_time, ifNull(toUnixTimestamp(props_url_first_seen), 0) AS first_indexed_time, download_http_code AS http_code, src_unparsed AS src_unparsed, src_root_hash AS src_root_hash, history_drop_reason AS history_drop_reason, meta_title AS meta_title, meta_descriptions AS meta_descriptions, attrs_boilerpipe_text AS attrs_boilerpipe_text, attrs_markdown AS attrs_markdown, attrs_readable_markdown AS attrs_readable_markdown, meta_canonical AS meta_canonical, ml_categories_json AS ml_categories_json, ml_types_json AS ml_types_json, ml_intent_types_json AS ml_intent_types_json, meta_language AS meta_language, attrs_author AS attrs_author, ifNull(toUnixTimestamp(attrs_publish_time), 0) AS attrs_publish_time, ifNull(toUnixTimestamp(attrs_original_publish_time), 0) AS attrs_original_publish_time, ifNull(attrs_is_republished, 0) AS attrs_is_republished, ifNull(attrs_nr_words, 0) AS attrs_nr_words, ifNull(attrs_boilerpipe_nr_words, 0) AS attrs_boilerpipe_nr_words, ifNull(body_ext_links_number, 0) AS body_ext_links_number, ifNull(body_int_links_number, 0) AS body_int_links_number, ifNull(meta_nofollow, 0) AS meta_nofollow, ifNull(meta_noarchive, 0) AS meta_noarchive, ifNull(props_was_rendered, 0) AS props_was_rendered, ifNull(src_redirect, \'\') AS src_redirect, ifNull(download_time_msec, 0) AS download_time_msec, ifNull(download_ttfb_msec, 0) AS download_ttfb_msec, ifNull(download_size, 0) AS download_size FROM crawler3.page_info_local FINAL PREWHERE (src_root_hash, src_unparsed) IN ((getAhrefsRootHashFromUnparsed(getAhrefsUnparsedNoserviceFromURL(\'https://www.healthline.com/health/depression/antidepressants-pros-and-cons\')), getAhrefsUnparsedNoserviceFromURL(\'https://www.healthline.com/health/depression/antidepressants-pros-and-cons\'))) FORMAT JSONEachRow'

Response:

{"found_url":"https:\/\/www.healthline.com\/health\/depression\/antidepressants-pros-and-cons","crawl_time":1770044505,"first_indexed_time":1638307949,"http_code":200,"src_unparsed":"com,healthline!www,\/health\/depression\/antidepressants-pros-and-cons s443","src_root_hash":"11478817528691466898","history_drop_reason":null,"meta_title":"Understanding the Pros and Cons of Antidepressants","meta_descriptions":["Antidepressants are used to treat depression, among other conditions. They can bring relief and are a common treatment option. However, there are pros and cons. We explore both."],"attrs_boilerpipe_text":"Some may be unsure about antidepressants or have concerns about side effects, psychological dependence, or\naddiction\n. Yet, antidepressants may help many people through different phases of\ndepression\n.\nDeciding to use an antidepressant as a treatment option is a personal decision involving a collaborative effort with your doctor. Doing your research, learning more about antidepressants, and talking with your doctor can help you make a choice that’s right for you.\nTaking antidepressants has many benefits. Knowing these can help inform your decision.\nThey’re effective at relieving symptoms\nResearch suggests that antidepressants may be more\neffective\nthan a placebo in treating major depression in adults.\nThey’re well-studied and generally safe\nThe Food and Drug Administration (FDA)\nhas approved all antidepressants\n, which means they’ve undergone rigorous testing and clinical trials.\nThey may help you succeed with other parts of your treatment plan\nYour treatment plan may include other aspects, like lifestyle changes or\ntherapy\n.\nIf your depression makes you\napathetic\nand\nlethargic\n, antidepressants can help restore your energy so you can:\nfulfill everyday activities\nparticipate in therapy\ncomplete other items in your treatment plan\nImproved quality of life\nare less reactive to negative life events\ncan examine things in a more balanced way\nhave improved concentration\nAs with any medication, antidepressants may have cons. These may vary for everyone, but knowing them can help you prepare.\nTalking with your doctor about any drawbacks can help determine whether the pros outweigh the cons.\nYou may need to try several kinds\nNot every antidepressant will work for everyone. You might have to\nswitch\nmore than once to find the best medication for you and your symptoms.\nAntidepressants can also take some time to reach their full effect.\nThey may affect your sex drive\nAntidepressants may reduce your sex drive or sexual functioning. Some antidepressants are more likely than others to do so.\nIf the side effects interfere with your life, ask your doctor about adjusting the dosage or finding other ways to manage them.\nThey can affect sleep\nDisrupted sleep is common among people with depression, but it’s usually not clear whether it’s a side effect of medication or a symptom of depression. If you have a\nsleep disorder\n, this can further affect your sleep.\nfluvoxamine\nmirtazapine\ntrazodone\n(only prescribed for sleep)\nparoxetine\nAntidepressants may also contribute to\ninsomnia\n, depending on:\nthe antidepressant\nthe dosage\nwhen you take it\nIf your antidepressant is interfering with your sleep, talk with your doctor.\nThey may affect your weight\nSome antidepressants list\nweight gain\nas a side effect, but other antidepressants carry a lower risk of weight gain. This doesn’t mean you\nwill\ngain or lose weight on antidepressants. Everyone’s bodies respond to them differently.\nThe potential for weight gain shouldn’t control your decision about antidepressants.\nThey may be costly\nEven with insurance and generic prescriptions, antidepressants might still be\ncostly\n.\nAlthough your insurance provider and plan determine the prescription cost, it may be beneficial to work with your doctor to see if they can:\nprovide an authorization request to your insurance company\nhelp you find a more affordable option\noffer you samples or coupons\nThey may have side effects\nSide effects\ncan be troublesome. They may include:\ndry mouth\nfatigue\nnausea\nheadache\nThese minor side effects tend to pass within a few weeks. If you continue to have side effects or significant ones that don’t go away, talk with your doctor.\nIf you choose to stop, you cannot stop abruptly\nIf you decide to stop taking antidepressants, abrupt stopping is not recommended, as\nwithdrawal symptoms\ncan occur.\nDo not stop taking your medication until you’ve talked with your doctor. They might put you on a\ntapering plan\nor switch you to a new medication. They can also monitor you for any withdrawal symptoms.\nAntidepressants are generally a safe and effective FDA-approved treatment option for depression. They may even help you succeed in other areas of your treatment plan. An improved quality of life may be on the other side of treatment.\nVarious classes of antidepressants are available, and different drugs are available within each class.\nFinding the right antidepressant for you can take time, and you may face sexual side effects or weight loss or gain, among other side effects. You might have to try more than one before you find one that works best for you.","attrs_markdown":"- Health Conditions\n  ### Health Conditions\n  [All](https:\/\/www.healthline.com\/directory\/topics)\n  \n  - [Breast Cancer](https:\/\/www.healthline.com\/breast-cancer)\n  - [Cancer Care](https:\/\/www.healthline.com\/cancer-care)\n  - [Caregiving for Alzheimer's Disease](https:\/\/www.healthline.com\/alzheimers-disease)\n  - [Chronic Kidney Disease](https:\/\/www.healthline.com\/ckd)\n  - [Chronic Obstructive Pulmonary Disease (COPD)](https:\/\/www.healthline.com\/copd)\n  - [Digestive Health](https:\/\/www.healthline.com\/digestive-health)\n  - [Eye Health](https:\/\/www.healthline.com\/eye-health)\n  - [Heart Health](https:\/\/www.healthline.com\/heart-health)\n  - [Menopause](https:\/\/www.healthline.com\/menopause)\n  - [Mental Health](https:\/\/www.healthline.com\/mental-health)\n  - [Migraine](https:\/\/www.healthline.com\/migraine)\n  - [Multiple Sclerosis (MS)](https:\/\/www.healthline.com\/multiple-sclerosis)\n  - 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[![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2024\/12\/navigation-icons_managing-type-2-diabetes-236x236-1.png) Managing Type 2 Diabetes](https:\/\/www.healthline.com\/program\/managing-type-2-diabetes-with-food-and-fitness)\n- Wellness\n  ### Wellness Topics\n  [All](https:\/\/www.healthline.com\/wellness)\n  \n  - [CBD](https:\/\/www.healthline.com\/cbd)\n  - [Fitness](https:\/\/www.healthline.com\/fitness)\n  - [Healthy Aging](https:\/\/www.healthline.com\/healthy-aging)\n  - [Hearing](https:\/\/www.healthline.com\/hearing-health)\n  - [Mental Well-Being](https:\/\/www.healthline.com\/mental-health)\n  - [Nutrition](https:\/\/www.healthline.com\/nutrition)\n  - [Parenthood](https:\/\/www.healthline.com\/parenthood)\n  - [Recipes](https:\/\/www.healthline.com\/recipes)\n  - [Sexual Health](https:\/\/www.healthline.com\/sexual-health)\n  - [Skin Care](https:\/\/www.healthline.com\/skincare)\n  - [Sleep Health](https:\/\/www.healthline.com\/sleep)\n  - [Vitamins and Supplements](https:\/\/www.healthline.com\/vitamins-supplements)\n  - 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[![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2024\/12\/navigation-icons-_understanding-inflammation-and-aging-236x236_360.png) Inflammation and Aging](https:\/\/www.healthline.com\/program\/understanding-inflammation-and-aging)\n  - [![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2024\/12\/navigation-icons-_cold-and-flu-236x236_360.png) Cold & Flu Season Survival Guide](https:\/\/www.healthline.com\/program\/cold-flu-survival-guide)\n  - [![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2024\/12\/navigation-icons_shes-good-for-real-236x236-1.png) She’s Good for Real](https:\/\/www.healthline.com\/program\/shes-good-for-real)\n- Tools\n  ### Featured\n  - [Video Series](https:\/\/www.healthline.com\/video)\n  - [Pill Identifier](https:\/\/www.healthline.com\/pill-identifier)\n  - [FindCare](https:\/\/care.healthline.com\/find-care)\n  - [Drugs A-Z](https:\/\/www.healthline.com\/drugs)\n  - [Medicare Plans by State](https:\/\/www.healthline.com\/about\/health-medicare-state-coverage)\n  \n  ### Lessons\n  [All](https:\/\/learn.healthline.com\/)\n  \n  - [Crohn’s and Ulcerative Colitis Essentials](https:\/\/www.healthline.com\/app\/inflammatory-bowel-disease?utm_source=lessonshome)\n  - [Diabetes Nutrition](https:\/\/www.healthline.com\/app\/type-2-diabetes?utm_source=lessonshome)\n  - [High Cholesterol](https:\/\/www.healthline.com\/app\/high-cholesterol?utm_source=lessonshome)\n  - [Taming Inflammation in Psoriasis](https:\/\/www.healthline.com\/app\/pso-inflammation?utm_source=lessonshome)\n  - [Taming Inflammation in Psoriatic Arthritis](https:\/\/www.healthline.com\/app\/psa-inflammation?utm_source=lessonshome)\n  \n  ### Newsletters\n  [All](https:\/\/www.healthline.com\/newsletter-signup)\n  \n  - [Anxiety and Depression](https:\/\/www.healthline.com\/newsletter-signup\/anxiety-and-depression)\n  - [Digestive Health](https:\/\/www.healthline.com\/newsletter-signup\/ibd)\n  - [Heart Health](https:\/\/www.healthline.com\/newsletter-signup\/heart-health)\n  - [Migraine](https:\/\/www.healthline.com\/newsletter-signup\/migraine)\n  - [Nutrition Edition](https:\/\/www.healthline.com\/newsletter-signup\/nutrition)\n  - [Type 2 Diabetes](https:\/\/www.healthline.com\/newsletter-signup\/type-2-diabetes)\n  - [Wellness Wire](https:\/\/www.healthline.com\/newsletter-signup\/wellness-wire)\n  \n  ### Lifestyle Quizzes\n  - [Find a Diet](https:\/\/activation.healthline.com\/assessment\/assessment\/diets\/prompt\/1?v=1&tc=120226&subid=hl_dietfinder_1_)\n  - [Find Healthy Snacks](https:\/\/activation.healthline.com\/assessment\/assessment\/pregnancy-snacks\/prompt\/1?v=1)\n  - [Weight Management](https:\/\/www.healthline.com\/nutrition\/weight-management-quiz)\n  - [How Well Do You Sleep?](https:\/\/www.healthline.com\/health\/healthy-sleep\/quiz-how-well-do-you-sleep#1)\n  - [Are You a Workaholic?](https:\/\/www.healthline.com\/health\/mental-health\/quiz-are-you-a-workaholic#quiz-are-you-a-workaholic)\n- Featured\n  ### Health News\n  [All](https:\/\/www.healthline.com\/health-news)\n  \n  - [Medicare 2026 Changes](https:\/\/www.healthline.com\/health-news\/medicare-open-enrollment-2026-key-changes)\n  - 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[Future of Health](https:\/\/www.healthline.com\/health\/video\/future-of-health)\n- Connect\n  ### Find Your Bezzy Community\n  Bezzy communities provide meaningful connections with others living with chronic conditions. Join Bezzy on the web or mobile app.\n  \n  [All](https:\/\/www.bezzy.com\/?utm_source=healthline&utm_medium=nav-bar-connections)\n  \n  - [![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2022\/01\/Bezzy-Breast-Cancer.png) Breast Cancer](https:\/\/www.bezzybc.com\/lp\/2\/?utm_source=healthline&utm_medium=hl-nav-bar-connections)\n  - [![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2022\/01\/Bezzy-Multiple-Sclerosis.png) Multiple Sclerosis](https:\/\/www.bezzyms.com\/?utm_source=healthline&utm_medium=hl-nav-bar-connections)\n  - [![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2024\/11\/Bezzy-DEP-Icon-Circle.png) Depression](https:\/\/www.bezzydepression.com\/?utm_source=healthline&utm_medium=hl-nav-bar-connections)\n  - [![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2025\/01\/Bezzy-MIG-Icon-Circle.png) Migraine](https:\/\/www.bezzymigraine.com\/?utm_source=healthline&utm_medium=hl-nav-bar-connections)\n  - [![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2024\/12\/Bezzy-T2D-Icon-Circle.png) Type 2 Diabetes](https:\/\/www.bezzyt2d.com\/?utm_source=healthline&utm_medium=hl-nav-bar-connections)\n  - [![](https:\/\/media.post.rvohealth.io\/wp-content\/uploads\/2022\/04\/Bezzy-PsO.png) Psoriasis](https:\/\/www.bezzypsoriasis.com\/?utm_source=healthline&utm_medium=hl-nav-bar-connections)\n  \n  ### Follow us on social media\n  Can't get enough? Connect with us for all things health.\n\nSubscribe\n\n[Anxiety and Depression](https:\/\/www.healthline.com\/anxiety-and-depression)\n\n- [Anxiety Treatment](https:\/\/www.healthline.com\/anxiety-and-depression\/anxiety-treatment)\n- [Depression Treatment](https:\/\/www.healthline.com\/anxiety-and-depression\/depression-treatment)\n- [Crisis Support](https:\/\/www.healthline.com\/anxiety-and-depression\/crisis-support)\n- [Navigating Therapy](https:\/\/www.healthline.com\/anxiety-and-depression\/therapy)\n- [Symptoms](https:\/\/www.healthline.com\/anxiety-and-depression\/symptom-management)\n- [Better Sleep](https:\/\/www.healthline.com\/anxiety-and-depression\/sleep-resources)\n- [Nutrition & Supplements](https:\/\/www.healthline.com\/anxiety-and-depression\/nutrition-supplements)\n- [Relationships](https:\/\/www.healthline.com\/anxiety-and-depression\/relationships)\n- [Emotional Well-Being](https:\/\/www.healthline.com\/anxiety-and-depression\/emotional-well-being)\n- [Physical Activity & Exercises](https:\/\/www.healthline.com\/anxiety-and-depression\/physical-activity-exercises)\n- [Resources for Doctors' Visits](https:\/\/www.healthline.com\/anxiety-and-depression\/doctor-guide)\n- [Comorbidities](https:\/\/www.healthline.com\/anxiety-and-depression\/comorbidities)\n\n# Antidepressants 101: Pros and Cons\n![](https:\/\/i0.wp.com\/post.healthline.com\/wp-content\/uploads\/2022\/05\/Yalda-Safai-500x500-Bio1.png?w=105&h=105)\n\n[Medically reviewed]() by [Yalda Safai, MD, MPH]() — Written by Jaime Herndon, MS, MPH, MFA —  [Updated on November 12, 2024]()\n\n- [What they are](https:\/\/www.healthline.com\/health\/depression\/antidepressants-pros-and-cons#what-they-are)\n- [Advantages](https:\/\/www.healthline.com\/health\/depression\/antidepressants-pros-and-cons#advantages)\n- [Disadvantages](https:\/\/www.healthline.com\/health\/depression\/antidepressants-pros-and-cons#disadvantages)\n- [Takeaway](https:\/\/www.healthline.com\/health\/depression\/antidepressants-pros-and-cons#takeaway)\n\n### Key takeaways\n- Antidepressants are considered a generally safe and effective treatment option for depression and are approved by the FDA.\n- Taking antidepressants may improve your overall quality of life and can help you engage more effectively in other aspects of a comprehensive treatment plan.\n- Finding the right antidepressant can take time and may involve managing side effects, so it’s important to consult with a medical professional to find the best option.\n\nSome may be unsure about antidepressants or have concerns about side effects, psychological dependence, or [addiction](https:\/\/www.healthline.com\/health\/antidepressants-arent-addicting). Yet, antidepressants may help many people through different phases of [depression](https:\/\/www.healthline.com\/health\/depression).\n\nDeciding to use an antidepressant as a treatment option is a personal decision involving a collaborative effort with your doctor. Doing your research, learning more about antidepressants, and talking with your doctor can help you make a choice that’s right for you.\n\n## [What are antidepressants?]()\n[Antidepressants](https:\/\/www.healthline.com\/health\/depression\/medication-list) are medications used to [treat depression](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538182\/), among other conditions. They:\n\n- affect [neurotransmitters](https:\/\/www.healthline.com\/health\/excitatory-neurotransmitters)\n- reduce the biological impact of [stress on the brain](https:\/\/www.healthline.com\/health\/mental-health\/tea-for-stress)\n- increase the brain’s capacity to cope with future [stress](https:\/\/www.healthline.com\/health\/stress)\n\nMany kinds of antidepressants are available. Common classes of antidepressants used to help treat depression include:\n\n- [selective serotonin reuptake inhibitors (SSRIs)](https:\/\/www.healthline.com\/health\/depression\/selective-serotonin-reuptake-inhibitors-ssris)\n- [serotonin and norepinephrine reuptake inhibitors (SNRIs)](https:\/\/www.healthline.com\/health\/depression\/serotonin-norepinephrine-reuptake-inhibitors-snris)\n- [tricyclic antidepressants](https:\/\/www.healthline.com\/health\/depression\/tricyclic-antidepressants-tcas)\n- noradrenergic and dopamine reuptake blocker\n- [monoamine oxidase inhibitors (MAOIs)](https:\/\/www.healthline.com\/health\/depression\/what-are-mao-inhibitors)\n\nLearn more about [antidepressant medications](https:\/\/www.healthline.com\/health\/depression\/medication-list).\n\n## [Advantages of taking antidepressants]()\nTaking antidepressants has many benefits. Knowing these can help inform your decision.\n\n### They’re effective at relieving symptoms\nResearch suggests that antidepressants may be more [effective](https:\/\/www.thelancet.com\/action\/showPdf?pii=S0140-6736%2817%2932802-7) than a placebo in treating major depression in adults.\n\n### They’re well-studied and generally safe\nThe Food and Drug Administration (FDA) [has approved all antidepressants](https:\/\/www.fda.gov\/consumers\/womens-health-topics\/depression-medicines), which means they’ve undergone rigorous testing and clinical trials.\n\n### They may help you succeed with other parts of your treatment plan\nYour treatment plan may include other aspects, like lifestyle changes or [therapy](https:\/\/www.healthline.com\/health\/depression\/types-of-depression-therapy).\n\nIf your depression makes you [apathetic](https:\/\/www.healthline.com\/health\/apathy) and [lethargic](https:\/\/www.healthline.com\/health\/lethargy), antidepressants can help restore your energy so you can:\n\n- fulfill everyday activities\n- participate in therapy\n- complete other items in your treatment plan\n### Improved quality of life\nPeople on antidepressants report an [improved quality of life](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6511371\/). They:\n\n- are less reactive to negative life events\n- can examine things in a more balanced way\n- have improved concentration\n\n### If you think you need antidepressants\nFinding [treatment](https:\/\/www.healthline.com\/health\/depression\/help-for-depression#finding-treatment) for depression is a big step and isn’t always easy. If you think you need antidepressants:\n\n- **Talk with your doctor:** They can screen for depression and talk about your [symptoms](https:\/\/www.healthline.com\/health\/depression\/recognizing-symptoms) to evaluate your situation. Some can prescribe antidepressants. Others may prescribe them and refer you to a counselor for talk therapy.\n- **Ask your doctor for a referral to a psychiatrist:** This is especially important if your depression is [severe](https:\/\/www.healthline.com\/health\/depression\/crippling-depression) or you have other medical or mental health conditions.\n\nThese organizations can help you find a psychiatrist or mental health professional:\n\n- [American Psychiatric Association’s (APA) Find a Psychiatrist search](http:\/\/finder.psychiatry.org\/?_ga=2.11690678.326351641.1619284610-806084773.1619284610)\n- [Substance Abuse and Mental Health Services Administration helpline](https:\/\/www.samhsa.gov\/find-help\/national-helpline)\n- [Anxiety & Depression Association of America Find a Therapist Directory](https:\/\/members.adaa.org\/page\/FATMain)\n- [Black Mental Health Alliance’s Connect with a Therapist search](https:\/\/docs.google.com\/forms\/d\/e\/1FAIpQLSfei-0WUN-rtpM3fNEI_9clGqgiLjDCIWgVwe0hyb2wuZvtVQ\/viewform)\n- [American Society of Hispanic Psychiatry’s Find a Physician search](http:\/\/www.americansocietyhispanicpsychiatry.com\/find-a-physician\/)\n- [World Professional Association for Transgender Health’s (WPATH) provider directory](https:\/\/www.wpath.org\/provider\/search?provider_directory_search_form%5Baddress%5D%5Bcountry%5D=US&provider_directory_search_form%5Baddress%5D%5Bstate%5D=FL&provider_directory_search_form%5Baddress%5D%5Bcity%5D=&provider_directory_search_form%5BfirstName%5D=&provider_directory_search_form%5BlastName%5D=&provider_directory_search_form%5Bspecialty%5D=)\n\n## [Potential disadvantages of antidepressants]()\nAs with any medication, antidepressants may have cons. These may vary for everyone, but knowing them can help you prepare.\n\nTalking with your doctor about any drawbacks can help determine whether the pros outweigh the cons.\n\n### You may need to try several kinds\nNot every antidepressant will work for everyone. You might have to [switch](https:\/\/www.healthline.com\/health\/mdd\/switching-antidepressants) more than once to find the best medication for you and your symptoms.\n\nAntidepressants can also take some time to reach their full effect.\n\n### They may affect your sex drive\nAntidepressants may reduce your sex drive or sexual functioning. Some antidepressants are more likely than others to do so.\n\n[About 1 in 5 adults](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7182464\/) in the United States experiences [sexual side effects](https:\/\/www.healthline.com\/health\/erectile-dysfunction\/antidepressant-sexual-side-effects#Sexual-side-effects-of-antidepressants) due to antidepressants.\n\nIf the side effects interfere with your life, ask your doctor about adjusting the dosage or finding other ways to manage them.\n\nLearn more about [managing the sexual side effects of antidepressants](https:\/\/www.healthline.com\/health\/erectile-dysfunction\/antidepressant-sexual-side-effects).\n\n### They can affect sleep\nDisrupted sleep is common among people with depression, but it’s usually not clear whether it’s a side effect of medication or a symptom of depression. If you have a [sleep disorder](https:\/\/www.healthline.com\/health\/sleep\/disorders), this can further affect your sleep.\n\nSome antidepressants have [sleep-related (sedating) effects](https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666915322000816), such as:\n\n- [fluvoxamine](https:\/\/www.healthline.com\/health\/drugs\/fluvoxamine-oral-capsule)\n- [mirtazapine](https:\/\/www.healthline.com\/health\/drugs\/mirtazapine-tablet-side-effects)\n- [trazodone](https:\/\/www.healthline.com\/health\/sleep\/trazodone-for-sleep) (only prescribed for sleep)\n- [paroxetine](https:\/\/www.healthline.com\/health\/drugs\/paroxetine-oral-tablet)\n\nAntidepressants may also contribute to [insomnia](https:\/\/www.healthline.com\/health\/insomnia\/treating-insomnia-and-depression), depending on:\n\n- the antidepressant\n- the dosage\n- when you take it\n\nIf your antidepressant is interfering with your sleep, talk with your doctor.\n\n### They may affect your weight\nSome antidepressants list [weight gain](https:\/\/www.healthline.com\/health\/antidepressants-that-cause-weight-gain#less-weight-gain) as a side effect, but other antidepressants carry a lower risk of weight gain. This doesn’t mean you **will** gain or lose weight on antidepressants. Everyone’s bodies respond to them differently.\n\nThe potential for weight gain shouldn’t control your decision about antidepressants.\n\nLearn more about antidepressant-related [weight gain](https:\/\/www.healthline.com\/health\/antidepressants-that-cause-weight-gain) and [weight loss](https:\/\/www.healthline.com\/health\/depression\/antidepressants-weight-loss).\n\n### They may be costly\nEven with insurance and generic prescriptions, antidepressants might still be [costly](https:\/\/www.healthline.com\/health\/depression\/how-much-does-depression-cost#medication-cost).\n\nAlthough your insurance provider and plan determine the prescription cost, it may be beneficial to work with your doctor to see if they can:\n\n- provide an authorization request to your insurance company\n- help you find a more affordable option\n- offer you samples or coupons\n\nLearn about [medicare coverage for antidepressants](https:\/\/www.healthline.com\/health\/medicare\/does-medicare-cover-antidepressants).\n\n### They may have side effects\n[Side effects](https:\/\/www.healthline.com\/health\/antidepressant-side-effects) can be troublesome. They may include:\n\n- dry mouth\n- [fatigue](https:\/\/www.healthline.com\/health\/depression\/fatigue)\n- nausea\n- [headache](https:\/\/www.healthline.com\/health\/headache\/depression-headaches)\n\nThese minor side effects tend to pass within a few weeks. If you continue to have side effects or significant ones that don’t go away, talk with your doctor.\n\nLearn more about the [side effects of antidepressants](https:\/\/www.healthline.com\/health\/depression-medications-and-side-effects).\n\n### If you choose to stop, you cannot stop abruptly\nIf you decide to stop taking antidepressants, abrupt stopping is not recommended, as [withdrawal symptoms](https:\/\/www.healthline.com\/health\/depression\/dangers-of-stopping-antidepressants) can occur.\n\nDo not stop taking your medication until you’ve talked with your doctor. They might put you on a [tapering plan](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK361016\/) or switch you to a new medication. They can also monitor you for any withdrawal symptoms.\n\nLearn more about [tapering off antidepressants](https:\/\/www.healthline.com\/health\/depression\/weaning-off-lexapro).\n\n## [The takeaway]()\nAntidepressants are generally a safe and effective FDA-approved treatment option for depression. They may even help you succeed in other areas of your treatment plan. An improved quality of life may be on the other side of treatment.\n\nVarious classes of antidepressants are available, and different drugs are available within each class.\n\nFinding the right antidepressant for you can take time, and you may face sexual side effects or weight loss or gain, among other side effects. You might have to try more than one before you find one that works best for you.\n\n### How we reviewed this article:\nSources\n\nHistory\n\nHealthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our [editorial policy](https:\/\/www.healthline.com\/about\/process).\n\n- Atmaca M. (2020). Selective serotonin reuptake inhibitor-induced sexual dysfunction: Current management perspectives.  \n  <https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7182464\/>\n- Cipriani A, et al. (2018). Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis.  \n  [https:\/\/www.thelancet.com\/action\/showPdf?pii=S0140-6736%2817%2932802-7](https:\/\/www.thelancet.com\/action\/showPdf?pii=S0140-6736%2817%2932802-7)\n- Depression: How effective are antidepressants? (2020).  \n  <https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK361016\/>\n- Depression medicines. (2019).  \n  <https:\/\/www.fda.gov\/consumers\/womens-health-topics\/depression-medicines>\n- Dzevlan A, et al. (2019). Quality of Life Assessment in antidepressant treatment of patients with depression and\/or anxiety disorder.  \n  <https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6511371\/>\n- Gandotra K, et al. (2022). Sertraline as an adjunctive treatment for insomnia comorbid with other mental health disorders.  \n  <https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666915322000816>\n- Sheffler ZM, et al. (2023). Antidepressants.  \n  <https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538182\/>\n\nShare this article\n\n![](https:\/\/i0.wp.com\/post.healthline.com\/wp-content\/uploads\/2022\/05\/Yalda-Safai-500x500-Bio1.png?w=105&h=105)\n\n[Medically reviewed]() by [Yalda Safai, MD, MPH]() — Written by Jaime Herndon, MS, MPH, MFA —  [Updated on November 12, 2024]()\n\n## related stories\n- [Can Antidepressants Have Potential to Cause Addiction?](https:\/\/www.healthline.com\/health\/antidepressants-arent-addicting?utm_source=ReadNext)\n- [How to Deal with the Sexual Side Effects of Depression Treatments](https:\/\/www.healthline.com\/health\/depression\/sexual-side-effects-depression-treatments?utm_source=ReadNext)\n- [Can You Overdose on Antidepressants?](https:\/\/www.healthline.com\/health\/can-you-overdose-on-antidepressants?utm_source=ReadNext)\n- [Are Antidepressants Safe For My Child To Take?](https:\/\/www.healthline.com\/health\/depression\/should-your-kid-go-on-antidepressants?utm_source=ReadNext)\n- [The Power of Glimmers and Joy Lists](https:\/\/www.healthline.com\/health\/the-power-of-glimmers-and-joy-lists?utm_source=ReadNext)\n\n### Read this next\n- [Can Antidepressants Have Potential to Cause Addiction?](https:\/\/www.healthline.com\/health\/antidepressants-arent-addicting?utm_source=ReadNext)\n  \n  Medically reviewed by [Timothy J. Legg, PhD, PsyD](https:\/\/www.healthline.com\/medical-team)\n  \n  [Addiction or dependence? Words have meaning — and when it comes to something as serious as addiction, getting them right matters.](https:\/\/www.healthline.com\/health\/antidepressants-arent-addicting?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/antidepressants-arent-addicting?utm_source=ReadNext)\n- [How to Deal with the Sexual Side Effects of Depression Treatments](https:\/\/www.healthline.com\/health\/depression\/sexual-side-effects-depression-treatments?utm_source=ReadNext)\n  \n  Medically reviewed by [Jennifer Litner, PhD, LMFT, CST](https:\/\/www.healthline.com\/medical-team)\n  \n  [Treatments for depression can impact your sexual function. Find out which treatments are most and least likely to have these effects and solutions you…](https:\/\/www.healthline.com\/health\/depression\/sexual-side-effects-depression-treatments?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/depression\/sexual-side-effects-depression-treatments?utm_source=ReadNext)\n- [Can You Overdose on Antidepressants?](https:\/\/www.healthline.com\/health\/can-you-overdose-on-antidepressants?utm_source=ReadNext)\n  \n  Medically reviewed by [Dena Westphalen, PharmD](https:\/\/www.healthline.com\/medical-team)\n  \n  [Antidepressants are used to treat symptoms of depression, chronic pain, and other mood disorders. But can you accidentally overdose? Are they safe?](https:\/\/www.healthline.com\/health\/can-you-overdose-on-antidepressants?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/can-you-overdose-on-antidepressants?utm_source=ReadNext)\n- [Are Antidepressants Safe For My Child To Take?](https:\/\/www.healthline.com\/health\/depression\/should-your-kid-go-on-antidepressants?utm_source=ReadNext)\n  \n  Medically reviewed by [Karen Gill, M.D.](https:\/\/www.healthline.com\/medical-team)\n  \n  [Deciding whether to put your child or teen on antidepressants can be a big decision. Read what experts have to say, plus signs to look for and what to…](https:\/\/www.healthline.com\/health\/depression\/should-your-kid-go-on-antidepressants?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/depression\/should-your-kid-go-on-antidepressants?utm_source=ReadNext)\n- [The Power of Glimmers and Joy Lists](https:\/\/www.healthline.com\/health\/the-power-of-glimmers-and-joy-lists?utm_source=ReadNext)\n  \n  Medically reviewed by [Jennifer Litner, PhD, LMFT, CST](https:\/\/www.healthline.com\/medical-team)\n  \n  [Looking for an easy and effective self-care tool? Glimmers and joy lists will make you smile.](https:\/\/www.healthline.com\/health\/the-power-of-glimmers-and-joy-lists?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/the-power-of-glimmers-and-joy-lists?utm_source=ReadNext)\n- [How Long Does Wellbutrin Take to Work? And Other Reddit Questions Answered](https:\/\/www.healthline.com\/health\/drugs\/wellbutrin-reddit?utm_source=ReadNext)\n  \n  [Get answers to common Reddit questions about starting Wellbutrin such as: How long does it take to start working? Can you make it work faster? And…](https:\/\/www.healthline.com\/health\/drugs\/wellbutrin-reddit?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/drugs\/wellbutrin-reddit?utm_source=ReadNext)\n- [Antidepressant Side Effects Like Weight, Blood Pressure Changes Vary by Drug](https:\/\/www.healthline.com\/health-news\/antidepressant-side-effects-vary-widely-by-drug?utm_source=ReadNext)\n  \n  [A large new study found that the side effects of antidepressants vary significantly by drug. Some medications resulted in weight loss, while others…](https:\/\/www.healthline.com\/health-news\/antidepressant-side-effects-vary-widely-by-drug?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health-news\/antidepressant-side-effects-vary-widely-by-drug?utm_source=ReadNext)\n- [Depression vs. Seasonal Affective Disorder (SAD): Comparison and When to Contact a Doctor](https:\/\/www.healthline.com\/health\/depression-vs-seasonal?utm_source=ReadNext)\n  \n  [Depression causes persistent feelings of sadness. Seasonal affective disorder (SAD) is when depression symptoms occur in winter months. Learn more…](https:\/\/www.healthline.com\/health\/depression-vs-seasonal?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/depression-vs-seasonal?utm_source=ReadNext)\n- [What Is the Geriatric Depression Scale?](https:\/\/www.healthline.com\/health\/geriatric-depression-scale?utm_source=ReadNext)\n  \n  [The geriatric depression scale is a screening tool that can help identify depression in older adults. Learn about the different versions, their uses…](https:\/\/www.healthline.com\/health\/geriatric-depression-scale?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/geriatric-depression-scale?utm_source=ReadNext)\n- [Postpartum Depression in Non-Birthing Partners and Parents](https:\/\/www.healthline.com\/health\/male-postpartum-depression?utm_source=ReadNext)\n  \n  Medically reviewed by [Matthew Boland, PhD](https:\/\/www.healthline.com\/medical-team)\n  \n  [Postpartum depression can affect any type of parent or caregiver. This includes fathers, cisgender men, and people with male reproductive organs…](https:\/\/www.healthline.com\/health\/male-postpartum-depression?utm_source=ReadNext)\n  \n  [READ MORE](https:\/\/www.healthline.com\/health\/male-postpartum-depression?utm_source=ReadNext)\n\n© 2026 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. [See additional information](https:\/\/www.healthline.com\/additional-information).\n\n- [About Us](https:\/\/www.healthline.com\/about)\n- [Contact Us](https:\/\/www.healthline.com\/about\/contact-us)\n- [Privacy Policy](https:\/\/www.healthline.com\/privacy-policy)\n- [Privacy Settings](https:\/\/www.healthline.com\/privacy-settings)\n- [Advertising Policy](https:\/\/www.healthline.com\/advertising-policy)\n- [Health Topics](https:\/\/www.healthline.com\/directory\/topics)\n\n- [Sitemap](https:\/\/www.healthline.com\/sitemap)\n- [Medical Affairs](https:\/\/www.healthline.com\/medical-team)\n- [Content Integrity](https:\/\/www.healthline.com\/about\/content-integrity)\n- [Newsletters](https:\/\/www.healthline.com\/newsletter-signup)\n- © 2026 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. [See additional information](https:\/\/www.healthline.com\/additional-information).\n\n© 2026 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. [See additional information](https:\/\/www.healthline.com\/additional-information).\n\n[About](https:\/\/www.healthlinemedia.com\/?utm_source=healthline.com&utm_medium=site&utm_campaign=footer&utm_content=about)[Careers](https:\/\/rvohealth.com\/careers)[Advertise with us](https:\/\/www.healthlinemedia.com\/advertise?utm_source=healthline.com&utm_medium=site&utm_campaign=footer&utm_content=advertise)\n\nOUR BRANDS\n\n[Healthline](https:\/\/www.healthline.com\/)[Medical News Today](https:\/\/www.medicalnewstoday.com\/)[Greatist](https:\/\/greatist.com\/)[Psych Central](https:\/\/psychcentral.com\/)[Bezzy](https:\/\/bezzy.com\/)\n\n![](http:\/\/b.scorecardresearch.com\/p?c1=2&c2=38584006&cv=3.9&cj=1&comscorekw=main)","attrs_readable_markdown":"Some may be unsure about antidepressants or have concerns about side effects, psychological dependence, or [addiction](https:\/\/www.healthline.com\/health\/antidepressants-arent-addicting). Yet, antidepressants may help many people through different phases of [depression](https:\/\/www.healthline.com\/health\/depression).\n\nDeciding to use an antidepressant as a treatment option is a personal decision involving a collaborative effort with your doctor. Doing your research, learning more about antidepressants, and talking with your doctor can help you make a choice that’s right for you.\n\nTaking antidepressants has many benefits. Knowing these can help inform your decision.\n\nThey’re effective at relieving symptoms\n\nResearch suggests that antidepressants may be more [effective](https:\/\/www.thelancet.com\/action\/showPdf?pii=S0140-6736%2817%2932802-7) than a placebo in treating major depression in adults.\n\nThey’re well-studied and generally safe\n\nThe Food and Drug Administration (FDA) [has approved all antidepressants](https:\/\/www.fda.gov\/consumers\/womens-health-topics\/depression-medicines), which means they’ve undergone rigorous testing and clinical trials.\n\nThey may help you succeed with other parts of your treatment plan\n\nYour treatment plan may include other aspects, like lifestyle changes or [therapy](https:\/\/www.healthline.com\/health\/depression\/types-of-depression-therapy).\n\nIf your depression makes you [apathetic](https:\/\/www.healthline.com\/health\/apathy) and [lethargic](https:\/\/www.healthline.com\/health\/lethargy), antidepressants can help restore your energy so you can:\n\n- fulfill everyday activities\n- participate in therapy\n- complete other items in your treatment plan\n\nImproved quality of life\n\n- are less reactive to negative life events\n- can examine things in a more balanced way\n- have improved concentration\n\nAs with any medication, antidepressants may have cons. These may vary for everyone, but knowing them can help you prepare.\n\nTalking with your doctor about any drawbacks can help determine whether the pros outweigh the cons.\n\nYou may need to try several kinds\n\nNot every antidepressant will work for everyone. You might have to [switch](https:\/\/www.healthline.com\/health\/mdd\/switching-antidepressants) more than once to find the best medication for you and your symptoms.\n\nAntidepressants can also take some time to reach their full effect.\n\nThey may affect your sex drive\n\nAntidepressants may reduce your sex drive or sexual functioning. Some antidepressants are more likely than others to do so.\n\nIf the side effects interfere with your life, ask your doctor about adjusting the dosage or finding other ways to manage them.\n\nThey can affect sleep\n\nDisrupted sleep is common among people with depression, but it’s usually not clear whether it’s a side effect of medication or a symptom of depression. If you have a [sleep disorder](https:\/\/www.healthline.com\/health\/sleep\/disorders), this can further affect your sleep.\n\n- [fluvoxamine](https:\/\/www.healthline.com\/health\/drugs\/fluvoxamine-oral-capsule)\n- [mirtazapine](https:\/\/www.healthline.com\/health\/drugs\/mirtazapine-tablet-side-effects)\n- [trazodone](https:\/\/www.healthline.com\/health\/sleep\/trazodone-for-sleep) (only prescribed for sleep)\n- [paroxetine](https:\/\/www.healthline.com\/health\/drugs\/paroxetine-oral-tablet)\n\nAntidepressants may also contribute to [insomnia](https:\/\/www.healthline.com\/health\/insomnia\/treating-insomnia-and-depression), depending on:\n\n- the antidepressant\n- the dosage\n- when you take it\n\nIf your antidepressant is interfering with your sleep, talk with your doctor.\n\nThey may affect your weight\n\nSome antidepressants list [weight gain](https:\/\/www.healthline.com\/health\/antidepressants-that-cause-weight-gain#less-weight-gain) as a side effect, but other antidepressants carry a lower risk of weight gain. This doesn’t mean you **will** gain or lose weight on antidepressants. Everyone’s bodies respond to them differently.\n\nThe potential for weight gain shouldn’t control your decision about antidepressants.\n\nThey may be costly\n\nEven with insurance and generic prescriptions, antidepressants might still be [costly](https:\/\/www.healthline.com\/health\/depression\/how-much-does-depression-cost#medication-cost).\n\nAlthough your insurance provider and plan determine the prescription cost, it may be beneficial to work with your doctor to see if they can:\n\n- provide an authorization request to your insurance company\n- help you find a more affordable option\n- offer you samples or coupons\n\nThey may have side effects\n\n[Side effects](https:\/\/www.healthline.com\/health\/antidepressant-side-effects) can be troublesome. They may include:\n\n- dry mouth\n- [fatigue](https:\/\/www.healthline.com\/health\/depression\/fatigue)\n- nausea\n- [headache](https:\/\/www.healthline.com\/health\/headache\/depression-headaches)\n\nThese minor side effects tend to pass within a few weeks. If you continue to have side effects or significant ones that don’t go away, talk with your doctor.\n\nIf you choose to stop, you cannot stop abruptly\n\nIf you decide to stop taking antidepressants, abrupt stopping is not recommended, as [withdrawal symptoms](https:\/\/www.healthline.com\/health\/depression\/dangers-of-stopping-antidepressants) can occur.\n\nDo not stop taking your medication until you’ve talked with your doctor. They might put you on a [tapering plan](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK361016\/) or switch you to a new medication. They can also monitor you for any withdrawal symptoms.\n\nAntidepressants are generally a safe and effective FDA-approved treatment option for depression. They may even help you succeed in other areas of your treatment plan. An improved quality of life may be on the other side of treatment.\n\nVarious classes of antidepressants are available, and different drugs are available within each class.\n\nFinding the right antidepressant for you can take time, and you may face sexual side effects or weight loss or gain, among other side effects. You might have to try more than one before you find one that works best for you.","meta_canonical":null,"ml_categories_json":"{\"\/Health\":995,\"\/Health\/Mental_Health\":962,\"\/Health\/Mental_Health\/Depression\":959}","ml_types_json":"{\"\/Article\":999,\"\/Article\/Comparisons\":797}","ml_intent_types_json":"{\"Informational\":999}","meta_language":"en","attrs_author":"Jaime Herndon","attrs_publish_time":0,"attrs_original_publish_time":1638307949,"attrs_is_republished":0,"attrs_nr_words":"2297","attrs_boilerpipe_nr_words":"728","body_ext_links_number":40,"body_int_links_number":168,"meta_nofollow":0,"meta_noarchive":0,"props_was_rendered":0,"src_redirect":"","download_time_msec":583,"download_ttfb_msec":575,"download_size":82750}

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Understanding the Pros and Cons of Antidepressants

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Antidepressants are used to treat depression, among other conditions. They can bring relief and are a common treatment option. However, there are pros and cons. We explore both.

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Some may be unsure about antidepressants or have concerns about side effects, psychological dependence, or addiction . Yet, antidepressants may help many people through different phases of depression . Deciding to use an antidepressant as a treatment option is a personal decision involving a collaborative effort with your doctor. Doing your research, learning more about antidepressants, and talking with your doctor can help you make a choice that’s right for you. Taking antidepressants has many benefits. Knowing these can help inform your decision. They’re effective at relieving symptoms Research suggests that antidepressants may be more effective than a placebo in treating major depression in adults. They’re well-studied and generally safe The Food and Drug Administration (FDA) has approved all antidepressants , which means they’ve undergone rigorous testing and clinical trials. They may help you succeed with other parts of your treatment plan Your treatment plan may include other aspects, like lifestyle changes or therapy . If your depression makes you apathetic and lethargic , antidepressants can help restore your energy so you can: fulfill everyday activities participate in therapy complete other items in your treatment plan Improved quality of life are less reactive to negative life events can examine things in a more balanced way have improved concentration As with any medication, antidepressants may have cons. These may vary for everyone, but knowing them can help you prepare. Talking with your doctor about any drawbacks can help determine whether the pros outweigh the cons. You may need to try several kinds Not every antidepressant will work for everyone. You might have to switch more than once to find the best medication for you and your symptoms. Antidepressants can also take some time to reach their full effect. They may affect your sex drive Antidepressants may reduce your sex drive or sexual functioning. Some antidepressants are more likely than others to do so. If the side effects interfere with your life, ask your doctor about adjusting the dosage or finding other ways to manage them. They can affect sleep Disrupted sleep is common among people with depression, but it’s usually not clear whether it’s a side effect of medication or a symptom of depression. If you have a sleep disorder , this can further affect your sleep. fluvoxamine mirtazapine trazodone (only prescribed for sleep) paroxetine Antidepressants may also contribute to insomnia , depending on: the antidepressant the dosage when you take it If your antidepressant is interfering with your sleep, talk with your doctor. They may affect your weight Some antidepressants list weight gain as a side effect, but other antidepressants carry a lower risk of weight gain. This doesn’t mean you will gain or lose weight on antidepressants. Everyone’s bodies respond to them differently. The potential for weight gain shouldn’t control your decision about antidepressants. They may be costly Even with insurance and generic prescriptions, antidepressants might still be costly . Although your insurance provider and plan determine the prescription cost, it may be beneficial to work with your doctor to see if they can: provide an authorization request to your insurance company help you find a more affordable option offer you samples or coupons They may have side effects Side effects can be troublesome. They may include: dry mouth fatigue nausea headache These minor side effects tend to pass within a few weeks. If you continue to have side effects or significant ones that don’t go away, talk with your doctor. If you choose to stop, you cannot stop abruptly If you decide to stop taking antidepressants, abrupt stopping is not recommended, as withdrawal symptoms can occur. Do not stop taking your medication until you’ve talked with your doctor. They might put you on a tapering plan or switch you to a new medication. They can also monitor you for any withdrawal symptoms. Antidepressants are generally a safe and effective FDA-approved treatment option for depression. They may even help you succeed in other areas of your treatment plan. An improved quality of life may be on the other side of treatment. Various classes of antidepressants are available, and different drugs are available within each class. Finding the right antidepressant for you can take time, and you may face sexual side effects or weight loss or gain, among other side effects. You might have to try more than one before you find one that works best for you.

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Connect with us for all things health. Subscribe [Anxiety and Depression](https://www.healthline.com/anxiety-and-depression) - [Anxiety Treatment](https://www.healthline.com/anxiety-and-depression/anxiety-treatment) - [Depression Treatment](https://www.healthline.com/anxiety-and-depression/depression-treatment) - [Crisis Support](https://www.healthline.com/anxiety-and-depression/crisis-support) - [Navigating Therapy](https://www.healthline.com/anxiety-and-depression/therapy) - [Symptoms](https://www.healthline.com/anxiety-and-depression/symptom-management) - [Better Sleep](https://www.healthline.com/anxiety-and-depression/sleep-resources) - [Nutrition & Supplements](https://www.healthline.com/anxiety-and-depression/nutrition-supplements) - [Relationships](https://www.healthline.com/anxiety-and-depression/relationships) - [Emotional Well-Being](https://www.healthline.com/anxiety-and-depression/emotional-well-being) - [Physical Activity & Exercises](https://www.healthline.com/anxiety-and-depression/physical-activity-exercises) - [Resources for Doctors' Visits](https://www.healthline.com/anxiety-and-depression/doctor-guide) - [Comorbidities](https://www.healthline.com/anxiety-and-depression/comorbidities) # Antidepressants 101: Pros and Cons ![](https://i0.wp.com/post.healthline.com/wp-content/uploads/2022/05/Yalda-Safai-500x500-Bio1.png?w=105&h=105) [Medically reviewed]() by [Yalda Safai, MD, MPH]() — Written by Jaime Herndon, MS, MPH, MFA — [Updated on November 12, 2024]() - [What they are](https://www.healthline.com/health/depression/antidepressants-pros-and-cons#what-they-are) - [Advantages](https://www.healthline.com/health/depression/antidepressants-pros-and-cons#advantages) - [Disadvantages](https://www.healthline.com/health/depression/antidepressants-pros-and-cons#disadvantages) - [Takeaway](https://www.healthline.com/health/depression/antidepressants-pros-and-cons#takeaway) ### Key takeaways - Antidepressants are considered a generally safe and effective treatment option for depression and are approved by the FDA. - Taking antidepressants may improve your overall quality of life and can help you engage more effectively in other aspects of a comprehensive treatment plan. - Finding the right antidepressant can take time and may involve managing side effects, so it’s important to consult with a medical professional to find the best option. Some may be unsure about antidepressants or have concerns about side effects, psychological dependence, or [addiction](https://www.healthline.com/health/antidepressants-arent-addicting). Yet, antidepressants may help many people through different phases of [depression](https://www.healthline.com/health/depression). Deciding to use an antidepressant as a treatment option is a personal decision involving a collaborative effort with your doctor. Doing your research, learning more about antidepressants, and talking with your doctor can help you make a choice that’s right for you. ## [What are antidepressants?]() [Antidepressants](https://www.healthline.com/health/depression/medication-list) are medications used to [treat depression](https://www.ncbi.nlm.nih.gov/books/NBK538182/), among other conditions. They: - affect [neurotransmitters](https://www.healthline.com/health/excitatory-neurotransmitters) - reduce the biological impact of [stress on the brain](https://www.healthline.com/health/mental-health/tea-for-stress) - increase the brain’s capacity to cope with future [stress](https://www.healthline.com/health/stress) Many kinds of antidepressants are available. Common classes of antidepressants used to help treat depression include: - [selective serotonin reuptake inhibitors (SSRIs)](https://www.healthline.com/health/depression/selective-serotonin-reuptake-inhibitors-ssris) - [serotonin and norepinephrine reuptake inhibitors (SNRIs)](https://www.healthline.com/health/depression/serotonin-norepinephrine-reuptake-inhibitors-snris) - [tricyclic antidepressants](https://www.healthline.com/health/depression/tricyclic-antidepressants-tcas) - noradrenergic and dopamine reuptake blocker - [monoamine oxidase inhibitors (MAOIs)](https://www.healthline.com/health/depression/what-are-mao-inhibitors) Learn more about [antidepressant medications](https://www.healthline.com/health/depression/medication-list). ## [Advantages of taking antidepressants]() Taking antidepressants has many benefits. Knowing these can help inform your decision. ### They’re effective at relieving symptoms Research suggests that antidepressants may be more [effective](https://www.thelancet.com/action/showPdf?pii=S0140-6736%2817%2932802-7) than a placebo in treating major depression in adults. ### They’re well-studied and generally safe The Food and Drug Administration (FDA) [has approved all antidepressants](https://www.fda.gov/consumers/womens-health-topics/depression-medicines), which means they’ve undergone rigorous testing and clinical trials. ### They may help you succeed with other parts of your treatment plan Your treatment plan may include other aspects, like lifestyle changes or [therapy](https://www.healthline.com/health/depression/types-of-depression-therapy). If your depression makes you [apathetic](https://www.healthline.com/health/apathy) and [lethargic](https://www.healthline.com/health/lethargy), antidepressants can help restore your energy so you can: - fulfill everyday activities - participate in therapy - complete other items in your treatment plan ### Improved quality of life People on antidepressants report an [improved quality of life](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511371/). They: - are less reactive to negative life events - can examine things in a more balanced way - have improved concentration ### If you think you need antidepressants Finding [treatment](https://www.healthline.com/health/depression/help-for-depression#finding-treatment) for depression is a big step and isn’t always easy. If you think you need antidepressants: - **Talk with your doctor:** They can screen for depression and talk about your [symptoms](https://www.healthline.com/health/depression/recognizing-symptoms) to evaluate your situation. Some can prescribe antidepressants. Others may prescribe them and refer you to a counselor for talk therapy. - **Ask your doctor for a referral to a psychiatrist:** This is especially important if your depression is [severe](https://www.healthline.com/health/depression/crippling-depression) or you have other medical or mental health conditions. These organizations can help you find a psychiatrist or mental health professional: - [American Psychiatric Association’s (APA) Find a Psychiatrist search](http://finder.psychiatry.org/?_ga=2.11690678.326351641.1619284610-806084773.1619284610) - [Substance Abuse and Mental Health Services Administration helpline](https://www.samhsa.gov/find-help/national-helpline) - [Anxiety & Depression Association of America Find a Therapist Directory](https://members.adaa.org/page/FATMain) - [Black Mental Health Alliance’s Connect with a Therapist search](https://docs.google.com/forms/d/e/1FAIpQLSfei-0WUN-rtpM3fNEI_9clGqgiLjDCIWgVwe0hyb2wuZvtVQ/viewform) - [American Society of Hispanic Psychiatry’s Find a Physician search](http://www.americansocietyhispanicpsychiatry.com/find-a-physician/) - [World Professional Association for Transgender Health’s (WPATH) provider directory](https://www.wpath.org/provider/search?provider_directory_search_form%5Baddress%5D%5Bcountry%5D=US&provider_directory_search_form%5Baddress%5D%5Bstate%5D=FL&provider_directory_search_form%5Baddress%5D%5Bcity%5D=&provider_directory_search_form%5BfirstName%5D=&provider_directory_search_form%5BlastName%5D=&provider_directory_search_form%5Bspecialty%5D=) ## [Potential disadvantages of antidepressants]() As with any medication, antidepressants may have cons. These may vary for everyone, but knowing them can help you prepare. Talking with your doctor about any drawbacks can help determine whether the pros outweigh the cons. ### You may need to try several kinds Not every antidepressant will work for everyone. You might have to [switch](https://www.healthline.com/health/mdd/switching-antidepressants) more than once to find the best medication for you and your symptoms. Antidepressants can also take some time to reach their full effect. ### They may affect your sex drive Antidepressants may reduce your sex drive or sexual functioning. Some antidepressants are more likely than others to do so. [About 1 in 5 adults](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182464/) in the United States experiences [sexual side effects](https://www.healthline.com/health/erectile-dysfunction/antidepressant-sexual-side-effects#Sexual-side-effects-of-antidepressants) due to antidepressants. If the side effects interfere with your life, ask your doctor about adjusting the dosage or finding other ways to manage them. Learn more about [managing the sexual side effects of antidepressants](https://www.healthline.com/health/erectile-dysfunction/antidepressant-sexual-side-effects). ### They can affect sleep Disrupted sleep is common among people with depression, but it’s usually not clear whether it’s a side effect of medication or a symptom of depression. If you have a [sleep disorder](https://www.healthline.com/health/sleep/disorders), this can further affect your sleep. Some antidepressants have [sleep-related (sedating) effects](https://www.sciencedirect.com/science/article/pii/S2666915322000816), such as: - [fluvoxamine](https://www.healthline.com/health/drugs/fluvoxamine-oral-capsule) - [mirtazapine](https://www.healthline.com/health/drugs/mirtazapine-tablet-side-effects) - [trazodone](https://www.healthline.com/health/sleep/trazodone-for-sleep) (only prescribed for sleep) - [paroxetine](https://www.healthline.com/health/drugs/paroxetine-oral-tablet) Antidepressants may also contribute to [insomnia](https://www.healthline.com/health/insomnia/treating-insomnia-and-depression), depending on: - the antidepressant - the dosage - when you take it If your antidepressant is interfering with your sleep, talk with your doctor. ### They may affect your weight Some antidepressants list [weight gain](https://www.healthline.com/health/antidepressants-that-cause-weight-gain#less-weight-gain) as a side effect, but other antidepressants carry a lower risk of weight gain. This doesn’t mean you **will** gain or lose weight on antidepressants. Everyone’s bodies respond to them differently. The potential for weight gain shouldn’t control your decision about antidepressants. Learn more about antidepressant-related [weight gain](https://www.healthline.com/health/antidepressants-that-cause-weight-gain) and [weight loss](https://www.healthline.com/health/depression/antidepressants-weight-loss). ### They may be costly Even with insurance and generic prescriptions, antidepressants might still be [costly](https://www.healthline.com/health/depression/how-much-does-depression-cost#medication-cost). Although your insurance provider and plan determine the prescription cost, it may be beneficial to work with your doctor to see if they can: - provide an authorization request to your insurance company - help you find a more affordable option - offer you samples or coupons Learn about [medicare coverage for antidepressants](https://www.healthline.com/health/medicare/does-medicare-cover-antidepressants). ### They may have side effects [Side effects](https://www.healthline.com/health/antidepressant-side-effects) can be troublesome. They may include: - dry mouth - [fatigue](https://www.healthline.com/health/depression/fatigue) - nausea - [headache](https://www.healthline.com/health/headache/depression-headaches) These minor side effects tend to pass within a few weeks. If you continue to have side effects or significant ones that don’t go away, talk with your doctor. Learn more about the [side effects of antidepressants](https://www.healthline.com/health/depression-medications-and-side-effects). ### If you choose to stop, you cannot stop abruptly If you decide to stop taking antidepressants, abrupt stopping is not recommended, as [withdrawal symptoms](https://www.healthline.com/health/depression/dangers-of-stopping-antidepressants) can occur. Do not stop taking your medication until you’ve talked with your doctor. They might put you on a [tapering plan](https://www.ncbi.nlm.nih.gov/books/NBK361016/) or switch you to a new medication. They can also monitor you for any withdrawal symptoms. Learn more about [tapering off antidepressants](https://www.healthline.com/health/depression/weaning-off-lexapro). ## [The takeaway]() Antidepressants are generally a safe and effective FDA-approved treatment option for depression. They may even help you succeed in other areas of your treatment plan. An improved quality of life may be on the other side of treatment. Various classes of antidepressants are available, and different drugs are available within each class. Finding the right antidepressant for you can take time, and you may face sexual side effects or weight loss or gain, among other side effects. You might have to try more than one before you find one that works best for you. ### How we reviewed this article: Sources History Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our [editorial policy](https://www.healthline.com/about/process). - Atmaca M. (2020). Selective serotonin reuptake inhibitor-induced sexual dysfunction: Current management perspectives. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182464/> - Cipriani A, et al. (2018). Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis. [https://www.thelancet.com/action/showPdf?pii=S0140-6736%2817%2932802-7](https://www.thelancet.com/action/showPdf?pii=S0140-6736%2817%2932802-7) - Depression: How effective are antidepressants? (2020). <https://www.ncbi.nlm.nih.gov/books/NBK361016/> - Depression medicines. (2019). <https://www.fda.gov/consumers/womens-health-topics/depression-medicines> - Dzevlan A, et al. (2019). Quality of Life Assessment in antidepressant treatment of patients with depression and/or anxiety disorder. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511371/> - Gandotra K, et al. (2022). Sertraline as an adjunctive treatment for insomnia comorbid with other mental health disorders. <https://www.sciencedirect.com/science/article/pii/S2666915322000816> - Sheffler ZM, et al. (2023). Antidepressants. <https://www.ncbi.nlm.nih.gov/books/NBK538182/> Share this article ![](https://i0.wp.com/post.healthline.com/wp-content/uploads/2022/05/Yalda-Safai-500x500-Bio1.png?w=105&h=105) [Medically reviewed]() by [Yalda Safai, MD, MPH]() — Written by Jaime Herndon, MS, MPH, MFA — [Updated on November 12, 2024]() ## related stories - [Can Antidepressants Have Potential to Cause Addiction?](https://www.healthline.com/health/antidepressants-arent-addicting?utm_source=ReadNext) - [How to Deal with the Sexual Side Effects of Depression Treatments](https://www.healthline.com/health/depression/sexual-side-effects-depression-treatments?utm_source=ReadNext) - [Can You Overdose on Antidepressants?](https://www.healthline.com/health/can-you-overdose-on-antidepressants?utm_source=ReadNext) - [Are Antidepressants Safe For My Child To Take?](https://www.healthline.com/health/depression/should-your-kid-go-on-antidepressants?utm_source=ReadNext) - [The Power of Glimmers and Joy Lists](https://www.healthline.com/health/the-power-of-glimmers-and-joy-lists?utm_source=ReadNext) ### Read this next - [Can Antidepressants Have Potential to Cause Addiction?](https://www.healthline.com/health/antidepressants-arent-addicting?utm_source=ReadNext) Medically reviewed by [Timothy J. Legg, PhD, PsyD](https://www.healthline.com/medical-team) [Addiction or dependence? Words have meaning — and when it comes to something as serious as addiction, getting them right matters.](https://www.healthline.com/health/antidepressants-arent-addicting?utm_source=ReadNext) [READ MORE](https://www.healthline.com/health/antidepressants-arent-addicting?utm_source=ReadNext) - [How to Deal with the Sexual Side Effects of Depression Treatments](https://www.healthline.com/health/depression/sexual-side-effects-depression-treatments?utm_source=ReadNext) Medically reviewed by [Jennifer Litner, PhD, LMFT, CST](https://www.healthline.com/medical-team) [Treatments for depression can impact your sexual function. Find out which treatments are most and least likely to have these effects and solutions you…](https://www.healthline.com/health/depression/sexual-side-effects-depression-treatments?utm_source=ReadNext) [READ MORE](https://www.healthline.com/health/depression/sexual-side-effects-depression-treatments?utm_source=ReadNext) - [Can You Overdose on Antidepressants?](https://www.healthline.com/health/can-you-overdose-on-antidepressants?utm_source=ReadNext) Medically reviewed by [Dena Westphalen, PharmD](https://www.healthline.com/medical-team) [Antidepressants are used to treat symptoms of depression, chronic pain, and other mood disorders. But can you accidentally overdose? Are they safe?](https://www.healthline.com/health/can-you-overdose-on-antidepressants?utm_source=ReadNext) [READ MORE](https://www.healthline.com/health/can-you-overdose-on-antidepressants?utm_source=ReadNext) - [Are Antidepressants Safe For My Child To Take?](https://www.healthline.com/health/depression/should-your-kid-go-on-antidepressants?utm_source=ReadNext) Medically reviewed by [Karen Gill, M.D.](https://www.healthline.com/medical-team) [Deciding whether to put your child or teen on antidepressants can be a big decision. Read what experts have to say, plus signs to look for and what to…](https://www.healthline.com/health/depression/should-your-kid-go-on-antidepressants?utm_source=ReadNext) [READ MORE](https://www.healthline.com/health/depression/should-your-kid-go-on-antidepressants?utm_source=ReadNext) - [The Power of Glimmers and Joy Lists](https://www.healthline.com/health/the-power-of-glimmers-and-joy-lists?utm_source=ReadNext) Medically reviewed by [Jennifer Litner, PhD, LMFT, CST](https://www.healthline.com/medical-team) [Looking for an easy and effective self-care tool? Glimmers and joy lists will make you smile.](https://www.healthline.com/health/the-power-of-glimmers-and-joy-lists?utm_source=ReadNext) [READ MORE](https://www.healthline.com/health/the-power-of-glimmers-and-joy-lists?utm_source=ReadNext) - [How Long Does Wellbutrin Take to Work? And Other Reddit Questions Answered](https://www.healthline.com/health/drugs/wellbutrin-reddit?utm_source=ReadNext) [Get answers to common Reddit questions about starting Wellbutrin such as: How long does it take to start working? Can you make it work faster? And…](https://www.healthline.com/health/drugs/wellbutrin-reddit?utm_source=ReadNext) [READ MORE](https://www.healthline.com/health/drugs/wellbutrin-reddit?utm_source=ReadNext) - [Antidepressant Side Effects Like Weight, Blood Pressure Changes Vary by Drug](https://www.healthline.com/health-news/antidepressant-side-effects-vary-widely-by-drug?utm_source=ReadNext) [A large new study found that the side effects of antidepressants vary significantly by drug. 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This includes fathers, cisgender men, and people with male reproductive organs…](https://www.healthline.com/health/male-postpartum-depression?utm_source=ReadNext) [READ MORE](https://www.healthline.com/health/male-postpartum-depression?utm_source=ReadNext) © 2026 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. 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Readable Markdown

Some may be unsure about antidepressants or have concerns about side effects, psychological dependence, or [addiction](https://www.healthline.com/health/antidepressants-arent-addicting). Yet, antidepressants may help many people through different phases of [depression](https://www.healthline.com/health/depression). Deciding to use an antidepressant as a treatment option is a personal decision involving a collaborative effort with your doctor. Doing your research, learning more about antidepressants, and talking with your doctor can help you make a choice that’s right for you. Taking antidepressants has many benefits. Knowing these can help inform your decision. They’re effective at relieving symptoms Research suggests that antidepressants may be more [effective](https://www.thelancet.com/action/showPdf?pii=S0140-6736%2817%2932802-7) than a placebo in treating major depression in adults. They’re well-studied and generally safe The Food and Drug Administration (FDA) [has approved all antidepressants](https://www.fda.gov/consumers/womens-health-topics/depression-medicines), which means they’ve undergone rigorous testing and clinical trials. They may help you succeed with other parts of your treatment plan Your treatment plan may include other aspects, like lifestyle changes or [therapy](https://www.healthline.com/health/depression/types-of-depression-therapy). If your depression makes you [apathetic](https://www.healthline.com/health/apathy) and [lethargic](https://www.healthline.com/health/lethargy), antidepressants can help restore your energy so you can: - fulfill everyday activities - participate in therapy - complete other items in your treatment plan Improved quality of life - are less reactive to negative life events - can examine things in a more balanced way - have improved concentration As with any medication, antidepressants may have cons. These may vary for everyone, but knowing them can help you prepare. Talking with your doctor about any drawbacks can help determine whether the pros outweigh the cons. You may need to try several kinds Not every antidepressant will work for everyone. You might have to [switch](https://www.healthline.com/health/mdd/switching-antidepressants) more than once to find the best medication for you and your symptoms. Antidepressants can also take some time to reach their full effect. They may affect your sex drive Antidepressants may reduce your sex drive or sexual functioning. Some antidepressants are more likely than others to do so. If the side effects interfere with your life, ask your doctor about adjusting the dosage or finding other ways to manage them. They can affect sleep Disrupted sleep is common among people with depression, but it’s usually not clear whether it’s a side effect of medication or a symptom of depression. If you have a [sleep disorder](https://www.healthline.com/health/sleep/disorders), this can further affect your sleep. - [fluvoxamine](https://www.healthline.com/health/drugs/fluvoxamine-oral-capsule) - [mirtazapine](https://www.healthline.com/health/drugs/mirtazapine-tablet-side-effects) - [trazodone](https://www.healthline.com/health/sleep/trazodone-for-sleep) (only prescribed for sleep) - [paroxetine](https://www.healthline.com/health/drugs/paroxetine-oral-tablet) Antidepressants may also contribute to [insomnia](https://www.healthline.com/health/insomnia/treating-insomnia-and-depression), depending on: - the antidepressant - the dosage - when you take it If your antidepressant is interfering with your sleep, talk with your doctor. They may affect your weight Some antidepressants list [weight gain](https://www.healthline.com/health/antidepressants-that-cause-weight-gain#less-weight-gain) as a side effect, but other antidepressants carry a lower risk of weight gain. This doesn’t mean you **will** gain or lose weight on antidepressants. Everyone’s bodies respond to them differently. The potential for weight gain shouldn’t control your decision about antidepressants. They may be costly Even with insurance and generic prescriptions, antidepressants might still be [costly](https://www.healthline.com/health/depression/how-much-does-depression-cost#medication-cost). Although your insurance provider and plan determine the prescription cost, it may be beneficial to work with your doctor to see if they can: - provide an authorization request to your insurance company - help you find a more affordable option - offer you samples or coupons They may have side effects [Side effects](https://www.healthline.com/health/antidepressant-side-effects) can be troublesome. They may include: - dry mouth - [fatigue](https://www.healthline.com/health/depression/fatigue) - nausea - [headache](https://www.healthline.com/health/headache/depression-headaches) These minor side effects tend to pass within a few weeks. If you continue to have side effects or significant ones that don’t go away, talk with your doctor. If you choose to stop, you cannot stop abruptly If you decide to stop taking antidepressants, abrupt stopping is not recommended, as [withdrawal symptoms](https://www.healthline.com/health/depression/dangers-of-stopping-antidepressants) can occur. Do not stop taking your medication until you’ve talked with your doctor. They might put you on a [tapering plan](https://www.ncbi.nlm.nih.gov/books/NBK361016/) or switch you to a new medication. They can also monitor you for any withdrawal symptoms. Antidepressants are generally a safe and effective FDA-approved treatment option for depression. They may even help you succeed in other areas of your treatment plan. An improved quality of life may be on the other side of treatment. Various classes of antidepressants are available, and different drugs are available within each class. Finding the right antidepressant for you can take time, and you may face sexual side effects or weight loss or gain, among other side effects. You might have to try more than one before you find one that works best for you.

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