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They work by increasing the amount of serotonin in the brain to elevate mood.  ### Why are ssris prescribed? 1. [Depression](https://www.goodrx.com/conditions/depression) (25%) 2. [Anxiety](https://www.goodrx.com/anxiety) (16%) 3. [Obsessive-Compulsive Disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder) (16%) 4. [Panic Disorder](https://www.goodrx.com/conditions/panic-disorder) (15%) 5. [PTSD](https://www.goodrx.com/conditions/ptsd) (15%) 6. [Eating Disorders](https://www.goodrx.com/conditions/eating-disorders) (7%) 7. [PMDD](https://www.goodrx.com/conditions/pmdd) (6%) 8. [Menopause](https://www.goodrx.com/conditions/menopause) (0%) How are these percentages calculated? ## Key takeaways Selective serotonin reuptake inhibitors (SSRIs) are used to treat depression, anxiety, and obsessive-compulsive disorder (OCD). They also have other uses, such as treating panic disorder and post-traumatic stress disorder (PTSD). SSRIs work by increasing the levels of serotonin, a chemical in your brain that helps improve mood. These medications are usually taken as oral pills. Examples include fluoxetine (Prozac), escitalopram (Lexapro), sertraline (Zoloft), citalopram (Celexa), paroxetine (Paxil), and vilazodone (Viibryd). You can talk to your healthcare provider to find the one that best fits your needs. Show less Prices for popular SSRIs medications Viewing 11 of 11 medications Popularity  ## [Prozac (fluoxetine)](https://www.goodrx.com/prozac) as low as[\$5](https://www.goodrx.com/prozac) [Fluoxetine](https://www.goodrx.com/fluoxetine) (Prozac) is an inexpensive drug used to treat mood problems such as [depression](https://www.goodrx.com/conditions/depression), [obsessive compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder), and [panic attacks](https://www.goodrx.com/conditions/panic-disorder). It can also treat certain [eating disorders](https://www.goodrx.com/conditions/eating-disorders). It is available in generic and brand versions. Generic fluoxetine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [See prices](https://www.goodrx.com/prozac)[More info](https://www.goodrx.com/prozac/what-is)  ## [Lexapro (escitalopram)](https://www.goodrx.com/lexapro) as low as[\$7](https://www.goodrx.com/lexapro) [Escitalopram](https://www.goodrx.com/escitalopram) (Lexapro) is an inexpensive drug used to treat [depression](https://www.goodrx.com/conditions/depression) and certain types of [anxiety](https://www.goodrx.com/conditions/anxiety). This drug is slightly more popular than comparable drugs. As of 2006, it is available in generic and brand versions. Generic escitalopram is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [See prices](https://www.goodrx.com/lexapro)[More info](https://www.goodrx.com/lexapro/what-is)  ## [Zoloft (sertraline)](https://www.goodrx.com/zoloft) as low as[\$7](https://www.goodrx.com/zoloft) [Sertraline](https://www.goodrx.com/sertraline) (Zoloft) is an inexpensive drug used to treat [depression](https://www.goodrx.com/conditions/depression). It may also be used to treat [obsessive compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder), [panic disorder](https://www.goodrx.com/conditions/panic-disorder), post-trauma stress, [premenstrual dysphoric disorder](https://www.goodrx.com/conditions/pmdd) ([PMDD](https://www.goodrx.com/conditions/pmdd)), or social [anxiety](https://www.goodrx.com/conditions/anxiety). It is more popular than comparable drugs. Generic sertraline is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [See prices](https://www.goodrx.com/zoloft)[More info](https://www.goodrx.com/zoloft/what-is)  ## [Celexa (citalopram)](https://www.goodrx.com/celexa) as low as[\$10](https://www.goodrx.com/celexa) [Citalopram](https://www.goodrx.com/citalopram) (Celexa) is an inexpensive drug used to treat [depression](https://www.goodrx.com/conditions/depression). It is slightly less popular than comparable drugs. This drug is available in generic and brand versions. Generic citalopram is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may lower. [See prices](https://www.goodrx.com/celexa)[More info](https://www.goodrx.com/celexa/what-is)  ## [Brisdelle (paroxetine)](https://www.goodrx.com/brisdelle) as low as[\$12](https://www.goodrx.com/brisdelle) [Paroxetine](https://www.goodrx.com/paroxetine) ([Paxil](https://www.goodrx.com/paxil), Brisdelle) is used to treat [depression](https://www.goodrx.com/conditions/depression). It may also be used to treat [anxiety disorders](https://www.goodrx.com/conditions/anxiety), [obsessive compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder), [panic attacks](https://www.goodrx.com/conditions/panic-disorder), post traumatic stress, and [premenstrual dysphoric disorder](https://www.goodrx.com/conditions/pmdd) ([PMDD](https://www.goodrx.com/conditions/pmdd)). It is slightly more popular than comparable drugs. It is available in generic and brand versions. Generic paroxetine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [See prices](https://www.goodrx.com/brisdelle)[More info](https://www.goodrx.com/brisdelle/what-is)  ## [Paxil (paroxetine)](https://www.goodrx.com/paxil) as low as[\$12](https://www.goodrx.com/paxil) [Paroxetine](https://www.goodrx.com/paroxetine) (Paxil, [Brisdelle](https://www.goodrx.com/brisdelle)) is used to treat [depression](https://www.goodrx.com/conditions/depression). It may also be used to treat [anxiety disorders](https://www.goodrx.com/conditions/anxiety), [obsessive compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder), [panic attacks](https://www.goodrx.com/conditions/panic-disorder), post traumatic stress, and [premenstrual dysphoric disorder](https://www.goodrx.com/conditions/pmdd) ([PMDD](https://www.goodrx.com/conditions/pmdd)). It is slightly more popular than comparable drugs. It is available in generic and brand versions. Generic paroxetine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [See prices](https://www.goodrx.com/paxil)[More info](https://www.goodrx.com/paxil/what-is)  ## [fluvoxamine](https://www.goodrx.com/fluvoxamine) as low as[\$14](https://www.goodrx.com/fluvoxamine) Fluvoxamine is an inexpensive drug used to treat [obsessive-compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder). It is slightly more popular than comparble drugs. Generic is only available as a generic drug; all brands have been discontinued. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [See prices](https://www.goodrx.com/fluvoxamine)[More info](https://www.goodrx.com/fluvoxamine/what-is)  ## [Paxil CR (paroxetine ER)](https://www.goodrx.com/paxil-cr) as low as[\$28](https://www.goodrx.com/paxil-cr) [PAROXETINE](https://www.goodrx.com/paroxetine) treats [depression](https://www.goodrx.com/conditions/depression), [anxiety](https://www.goodrx.com/conditions/anxiety), [obsessive-compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder) ([OCD](https://www.goodrx.com/conditions/obsessive-compulsive-disorder)), [post-traumatic stress disorder](https://www.goodrx.com/conditions/ptsd) ([PTSD](https://www.goodrx.com/conditions/ptsd)), and [premenstrual dysphoric disorder](https://www.goodrx.com/conditions/pmdd) ([PMDD](https://www.goodrx.com/conditions/pmdd)). It increases the amount of serotonin in the brain, a hormone that helps regulate mood. It belongs to a group of medications called [SSRIs](https://www.goodrx.com/classes/ssris). [See prices](https://www.goodrx.com/paxil-cr)[More info](https://www.goodrx.com/paxil-cr/what-is)  ## [Viibryd (vilazodone)](https://www.goodrx.com/viibryd) as low as[\$40](https://www.goodrx.com/viibryd) [Vilazodone](https://www.goodrx.com/vilazodone) (Viibryd) is an expensive drug used to treat [depression](https://www.goodrx.com/conditions/depression). This drug is less popular than comparable drugs. There are currently no generic alternatives to Viibryd. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [See prices](https://www.goodrx.com/viibryd)[More info](https://www.goodrx.com/viibryd/what-is)  ## [fluvoxamine ER](https://www.goodrx.com/fluvoxamine-er) as low as[\$75](https://www.goodrx.com/fluvoxamine-er) [FLUVOXAMINE](https://www.goodrx.com/fluvoxamine) treats [obsessive-compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder) ([OCD](https://www.goodrx.com/conditions/obsessive-compulsive-disorder)). It increases the amount of serotonin in the brain, a substance that helps regulate mood. It belongs to a group of medications called [SSRIs](https://www.goodrx.com/classes/ssris). [See prices](https://www.goodrx.com/fluvoxamine-er)[More info](https://www.goodrx.com/fluvoxamine-er/what-is)  ## [Pexeva](https://www.goodrx.com/pexeva) as low as[\$457](https://www.goodrx.com/pexeva) [PAROXETINE](https://www.goodrx.com/paroxetine) treats [depression](https://www.goodrx.com/conditions/depression), [anxiety](https://www.goodrx.com/conditions/anxiety), [obsessive-compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder) ([OCD](https://www.goodrx.com/conditions/obsessive-compulsive-disorder)), [post-traumatic stress disorder](https://www.goodrx.com/conditions/ptsd) ([PTSD](https://www.goodrx.com/conditions/ptsd)), and [premenstrual dysphoric disorder](https://www.goodrx.com/conditions/pmdd) ([PMDD](https://www.goodrx.com/conditions/pmdd)). It increases the amount of serotonin in the brain, a hormone that helps regulate mood. It belongs to a group of medications called [SSRIs](https://www.goodrx.com/classes/ssris). [See prices](https://www.goodrx.com/pexeva)[More info](https://www.goodrx.com/pexeva/what-is) Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions. #### Subscribe and save Get prescription saving tips and more from GoodRx Health. Enter your email to sign up #### Compare other SSRIs drugs [Abilify vs Lexapro](https://www.goodrx.com/compare/abilify-vs-lexapro)[Anafranil vs Lexapro](https://www.goodrx.com/compare/anafranil-vs-lexapro)[Bupropion vs Lexapro](https://www.goodrx.com/compare/bupropion-vs-lexapro)[Buspar vs Lexapro](https://www.goodrx.com/compare/buspar-vs-lexapro)[Celexa vs Lexapro](https://www.goodrx.com/compare/celexa-vs-lexapro)[Citalopram vs Lexapro](https://www.goodrx.com/compare/citalopram-vs-lexapro)[Clonazepam vs Lexapro](https://www.goodrx.com/compare/clonazepam-vs-lexapro)[Hydroxyzine vs Lexapro](https://www.goodrx.com/compare/hydroxyzine-vs-lexapro)[Lexapro vs Adderall](https://www.goodrx.com/compare/lexapro-vs-adderall)[Lexapro vs Buspar](https://www.goodrx.com/compare/lexapro-vs-buspar)[Lexapro vs Cymbalta](https://www.goodrx.com/compare/lexapro-vs-cymbalta)[Lexapro vs Effexor](https://www.goodrx.com/compare/lexapro-vs-effexor)[Lexapro vs Lyrica](https://www.goodrx.com/compare/lexapro-vs-lyrica)[Lexapro vs Nefazodone](https://www.goodrx.com/compare/lexapro-vs-nefazodone)[Lexapro vs Oleptro](https://www.goodrx.com/compare/lexapro-vs-oleptro)[Lexapro vs Pristiq](https://www.goodrx.com/compare/lexapro-vs-pristiq)[Lexapro vs Prozac](https://www.goodrx.com/compare/lexapro-vs-prozac)[Lexapro vs Xanax](https://www.goodrx.com/compare/lexapro-vs-xanax)[Lexapro vs Zoloft](https://www.goodrx.com/compare/lexapro-vs-zoloft)[Luvox vs Lexapro](https://www.goodrx.com/compare/luvox-vs-lexapro)[Paxil vs Lexapro](https://www.goodrx.com/compare/paxil-vs-lexapro)[Trintellix vs Lexapro](https://www.goodrx.com/compare/trintellix-vs-lexapro)[Viibryd vs Lexapro](https://www.goodrx.com/compare/viibryd-vs-lexapro)[Wellbutrin vs Lexapro](https://www.goodrx.com/compare/wellbutrin-vs-lexapro)[Adderall vs Concerta](https://www.goodrx.com/compare/adderall-vs-concerta)[Adderall vs Strattera](https://www.goodrx.com/compare/adderall-vs-strattera)[Adderall vs Xanax](https://www.goodrx.com/compare/adderall-vs-xanax)[Adderall-xr vs Adderall](https://www.goodrx.com/compare/adderall-xr-vs-adderall)[Armodafinil vs Adderall](https://www.goodrx.com/compare/armodafinil-vs-adderall)[Ativan vs Adderall](https://www.goodrx.com/compare/ativan-vs-adderall) View more ### Latest Articles [ Which Medications Work Best to Treat Postpartum Depression? 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Viewing 11 of 11 medications [Escitalopram](https://www.goodrx.com/escitalopram) (Lexapro) is an inexpensive drug used to treat [depression](https://www.goodrx.com/conditions/depression) and certain types of [anxiety](https://www.goodrx.com/conditions/anxiety). This drug is slightly more popular than comparable drugs. As of 2006, it is available in generic and brand versions. Generic escitalopram is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [Citalopram](https://www.goodrx.com/citalopram) (Celexa) is an inexpensive drug used to treat [depression](https://www.goodrx.com/conditions/depression). It is slightly less popular than comparable drugs. This drug is available in generic and brand versions. Generic citalopram is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may lower. Fluvoxamine is an inexpensive drug used to treat [obsessive-compulsive disorder](https://www.goodrx.com/conditions/obsessive-compulsive-disorder). It is slightly more popular than comparble drugs. Generic is only available as a generic drug; all brands have been discontinued. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. [Vilazodone](https://www.goodrx.com/vilazodone) (Viibryd) is an expensive drug used to treat [depression](https://www.goodrx.com/conditions/depression). This drug is less popular than comparable drugs. There are currently no generic alternatives to Viibryd. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.