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URLhttps://www.gavi.org/vaccineswork/new-survey-suggests-reinfection-worsens-long-covid
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Meta TitleNew survey suggests reinfection worsens Long COVID
Meta DescriptionSurvey indicates that getting reinfected worsens symptoms of Long COVID or triggers a recurrence of symptoms in people who have recovered.
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What is the research about? Around one in eight people who get COVID-19 go on to develop Long COVID – post-infection symptoms persisting for at least a month. Reinfections of COVID-19 even in people who have been vaccinated have become increasingly common since the emergence of the Omicron variant. The results also underline the importance of avoiding reinfection even if people are fully vaccinated and have recovered from Long COVID. So what effect does a reinfection have on someone who has already had COVID-19 and is now suffering from Long COVID? The UK charities Long COVID Kids and Long COVID Support conducted an internet survey to understand people’s experiences. What did the researchers do? The survey was sent out to people with Long COVID in 30 countries including the UK, US, France and Canada and was open from 4 April 2022 to 19 June 2022. Responses were received from 484 adults and 112 children and young people who’d had at least two COVID-19 infections. Have you read? Mental health conditions raise risk of Long COVID Long COVID affects one in eight, says Lancet study Long COVID and the workplace: What employers could do better What did they find? The results were similar across adults and young people. As many as 89% of respondents first got Long COVID after their first infection, compared with 10% after the second infection, and just 1% after the third infection. Overwhelmingly, reinfection worsened the symptoms of Long COVID in most people who were still symptomatic. In those who still had Long COVID at the time of reinfection, 80% saw their symptoms worsen vs. 10% who saw their Long COVID symptoms improve. Around 85% saw old symptoms return or new additional symptoms vs. 10% who had a resolution or improvement of symptoms. In 60% of people who were in recovery or remission with Long COVID, reinfection caused a recurrence of Long COVID. What does this mean? The researchers say this is one of the first published studies of the effect of reinfection on Long COVID and their findings indicate the need for more investigations. The findings indicate that, as most people get Long COVID after their first infection, avoiding infection especially in children is critical. The results also underline the importance of avoiding reinfection even if people are fully vaccinated and have recovered from Long COVID.
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[Skip to main content](https://www.gavi.org/vaccineswork/new-survey-suggests-reinfection-worsens-long-covid#main-content) [![Home](https://www.gavi.org/themes/custom/gavi/logo-white-gavi.png) Back to main site](https://www.gavi.org/) - [English](https://www.gavi.org/vaccineswork/new-survey-suggests-reinfection-worsens-long-covid) - [Français](https://www.gavi.org/fr/homepage) [![Home](https://www.gavi.org/sites/default/files/2022-03/vw-logo.svg)](https://www.gavi.org/vaccineswork) ## Main navigation - Vaccineswork - [About](https://www.gavi.org/vaccineswork/about) - [Stories](https://www.gavi.org/vaccineswork/topics/stories) - [News](https://www.gavi.org/vaccineswork/topics/lab) - [History](https://www.gavi.org/vaccineswork/topics/history) - [Emerging Threats](https://www.gavi.org/vaccineswork/topics/emerging-threats) - [Opinions](https://www.gavi.org/vaccineswork/topics/opinions) - [Search](https://www.gavi.org/vaccineswork/search) ## Vaccineswork - Search - [Search](https://www.gavi.org/vaccineswork/search) [![Home](https://www.gavi.org/sites/default/files/2022-03/vw-logo.svg)](https://www.gavi.org/vaccineswork) ## Main navigation - Vaccineswork - [About](https://www.gavi.org/vaccineswork/about) - [Stories](https://www.gavi.org/vaccineswork/topics/stories) - [News](https://www.gavi.org/vaccineswork/topics/lab) - [History](https://www.gavi.org/vaccineswork/topics/history) - [Emerging Threats](https://www.gavi.org/vaccineswork/topics/emerging-threats) - [Opinions](https://www.gavi.org/vaccineswork/topics/opinions) - [Search](https://www.gavi.org/vaccineswork/search) [The science behind COVID-19](https://www.gavi.org/vaccineswork/topics/science) [Research summary](https://www.gavi.org/vaccineswork/tag/research-summary)[COVID-19](https://www.gavi.org/vaccineswork/tag/covid19)[Explainer](https://www.gavi.org/vaccineswork/tag/explainer) # New survey suggests reinfection worsens Long COVID Survey indicates that getting reinfected worsens symptoms of Long COVID or triggers a recurrence of symptoms in people who have recovered. - **15 September 2022** - 2 min read - **by** [Priya Joi](https://www.gavi.org/vaccineswork/authors/priya-joi) - Republish this article ###### Republish this article **Disclaimer** If you would like to republish this article, please follow these steps: use the HTML below; do not edit the text; include the author’s byline; credit VaccinesWork as the original source; and include the page view counter script. \<article\> \<h1\> \<span\>New survey suggests reinfection worsens Long COVID\</span\> \</h1\> \<div\> \<div\>\<p\>Survey indicates that getting reinfected worsens symptoms of Long COVID or triggers a recurrence of symptoms in people who have recovered.\</p\> \</div\> \</div\> \<ul\> \<li\> \<b\>15 September 2022\</b\> \</li\> \<li\> \<b class="me-2"\>by\</b\> \<span\> \<a href="https://www.gavi.org/vaccineswork/authors/priya-joi" hreflang="en"\>Priya Joi\</a\> \</span\> \</li\> \</ul\> \<div\> \<div\> \<div\> \<div\> \<div\> \<p\> \</p\> \<h3\>What is the research about?\</h3\> \<p\>Around \<a href="https://www.gavi.org/vaccineswork/long-covid-affects-one-eight-says-lancet-study" title="Long COVID affects one in eight, says Lancet study"\>one in eight people\</a\> who get COVID-19 go on to develop Long COVID – post-infection symptoms persisting for at least a month. Reinfections of COVID-19 even in people who have been vaccinated have become increasingly common since the emergence of the Omicron variant.\</p\> \<blockquote\> \<h2\>The results also underline the importance of avoiding reinfection even if people are fully vaccinated and have recovered from Long COVID.\</h2\> \</blockquote\> \<p\>So what effect does a reinfection have on someone who has already had COVID-19 and is now suffering from Long COVID? The UK charities Long COVID Kids and Long COVID Support conducted an internet survey to understand people’s experiences.\</p\> \<h3\>What did the researchers do?\</h3\> \<p\>The \<a href="https://www.longcovidkids.org/post/a-world-first-effect-of-covid-reinfection-on-people-living-with-long-covid"\>survey\</a\> was sent out to people with Long COVID in 30 countries including the UK, US, France and Canada and was open from 4 April 2022 to 19 June 2022. Responses were received from 484 adults and 112 children and young people who’d had at least two COVID-19 infections.\</p\> \<div\> \<h4\>Have you read?\</h4\> \<ul\> \<li\>\<a href="https://www.gavi.org/vaccineswork/mental-health-conditions-raises-risk-long-covid" title="Mental health conditions raise risk of Long COVID"\>Mental health conditions raise risk of Long COVID\</a\>\</li\> \<li\>\<a href="https://www.gavi.org/vaccineswork/long-covid-affects-one-eight-says-lancet-study" title="Long COVID affects one in eight, says Lancet study"\>Long COVID affects one in eight, says Lancet study\</a\>\</li\> \<li\>\<a href="https://www.gavi.org/vaccineswork/long-covid-and-workplace-what-employers-could-do-better" title="Long COVID and the workplace: What employers could do better"\>Long COVID and the workplace: What employers could do better\</a\>\</li\> \</ul\> \</div\> \<h3\>What did they find?\</h3\> \<p\>The results were similar across adults and young people. As many as 89% of respondents first got Long COVID after their first infection, compared with 10% after the second infection, and just 1% after the third infection. Overwhelmingly, reinfection worsened the symptoms of Long COVID in most people who were still symptomatic.\</p\> \<p\>In those who still had Long COVID at the time of reinfection, 80% saw their symptoms worsen vs. 10% who saw their Long COVID symptoms improve. Around 85% saw old symptoms return or new additional symptoms vs. 10% who had a resolution or improvement of symptoms.\</p\> \<p\>In 60% of people who were in recovery or remission with Long COVID, reinfection caused a recurrence of Long COVID.\</p\> \<h3\>What does this mean?\</h3\> \<p\>The researchers say this is one of the first published studies of the effect of reinfection on Long COVID and their findings indicate the need for more investigations. The findings indicate that, as most people get Long COVID after their first infection, avoiding infection especially in children is critical. The results also underline the importance of avoiding reinfection even if people are fully vaccinated and have recovered from Long COVID.\</p\> \</div\> \</div\> \</div\> \</div\> \</div\> \<p\> \<a target="\_blank" rel="noopener noreferrer" href="https://www.gavi.org/vaccineswork/new-survey-suggests-reinfection-worsens-long-covid"\>Original article\</a\> \</p\>\<p\>This article was originally published on \<a target="\_blank" rel="noopener noreferrer" href="https://www.gavi.org/vaccineswork"\>VaccinesWork\</a\> \</p\>\<script\>(function(w,d,s,l,i){w\[l\]=w\[l\]\|\|\[\];w\[l\].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)\[0\], j=d.createElement(s),dl=l!='dataLayer'?'\&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-M7H54VD');\</script\>\<noscript\>\<iframe src="https://www.googletagmanager.com/ns.html?id=GTM-M7H54VD" height="0" width="0" style="display:none;visibility:hidden"\>\</iframe\>\</noscript\>\</article\> Copy html - [Add as preferred Google source](https://www.google.com/preferences/source?q=https://www.gavi.org "Add us as a preferred source for your Google searches") ![Photo by Pavel Danilyuk from Pexels](data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E) Photo by Pavel Danilyuk from Pexels ### What is the research about? Around [one in eight people](https://www.gavi.org/vaccineswork/long-covid-affects-one-eight-says-lancet-study "Long COVID affects one in eight, says Lancet study") who get COVID-19 go on to develop Long COVID – post-infection symptoms persisting for at least a month. Reinfections of COVID-19 even in people who have been vaccinated have become increasingly common since the emergence of the Omicron variant. > ## The results also underline the importance of avoiding reinfection even if people are fully vaccinated and have recovered from Long COVID. So what effect does a reinfection have on someone who has already had COVID-19 and is now suffering from Long COVID? The UK charities Long COVID Kids and Long COVID Support conducted an internet survey to understand people’s experiences. ### What did the researchers do? The [survey](https://www.longcovidkids.org/post/a-world-first-effect-of-covid-reinfection-on-people-living-with-long-covid) was sent out to people with Long COVID in 30 countries including the UK, US, France and Canada and was open from 4 April 2022 to 19 June 2022. Responses were received from 484 adults and 112 children and young people who’d had at least two COVID-19 infections. #### Have you read? - [Mental health conditions raise risk of Long COVID](https://www.gavi.org/vaccineswork/mental-health-conditions-raises-risk-long-covid "Mental health conditions raise risk of Long COVID") - [Long COVID affects one in eight, says Lancet study](https://www.gavi.org/vaccineswork/long-covid-affects-one-eight-says-lancet-study "Long COVID affects one in eight, says Lancet study") - [Long COVID and the workplace: What employers could do better](https://www.gavi.org/vaccineswork/long-covid-and-workplace-what-employers-could-do-better "Long COVID and the workplace: What employers could do better") ### What did they find? The results were similar across adults and young people. As many as 89% of respondents first got Long COVID after their first infection, compared with 10% after the second infection, and just 1% after the third infection. Overwhelmingly, reinfection worsened the symptoms of Long COVID in most people who were still symptomatic. In those who still had Long COVID at the time of reinfection, 80% saw their symptoms worsen vs. 10% who saw their Long COVID symptoms improve. Around 85% saw old symptoms return or new additional symptoms vs. 10% who had a resolution or improvement of symptoms. In 60% of people who were in recovery or remission with Long COVID, reinfection caused a recurrence of Long COVID. ### What does this mean? The researchers say this is one of the first published studies of the effect of reinfection on Long COVID and their findings indicate the need for more investigations. The findings indicate that, as most people get Long COVID after their first infection, avoiding infection especially in children is critical. The results also underline the importance of avoiding reinfection even if people are fully vaccinated and have recovered from Long COVID. *** ## More from Priya Joi [View all](https://www.gavi.org/vaccineswork/authors/priya-joi) [![Health worker prepares vaccine injection. Photo by Nappy on Unsplash](data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E)](https://www.gavi.org/vaccineswork/does-obesity-make-vaccines-less-effective) ## [Does obesity make vaccines less effective?](https://www.gavi.org/vaccineswork/does-obesity-make-vaccines-less-effective) 16 Apr 2026 5 min read [Research summary](https://www.gavi.org/vaccineswork/tag/research-summary) [![Soil. 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Drought is making it worse](https://www.gavi.org/vaccineswork/world-running-out-antibiotics-work-drought-making-it-worse) 13 Apr 2026 4 min read [Antimicrobial resistance](https://www.gavi.org/vaccineswork/tag/amr)[Climate change](https://www.gavi.org/vaccineswork/tag/climate-change) [![Photo by Alexander Mass on Unsplash](data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E)](https://www.gavi.org/vaccineswork/six-lessons-human-health-can-learn-animal-vaccination-programmes) ## [Six lessons human health can learn from animal vaccination programmes](https://www.gavi.org/vaccineswork/six-lessons-human-health-can-learn-animal-vaccination-programmes) 7 Apr 2026 6 min read [Rabies](https://www.gavi.org/vaccineswork/tag/rabies)[One health](https://www.gavi.org/vaccineswork/tag/one-health) [![Elderly person sleeping on a train. Photo by Zoë Gayah Jonker on Unsplash](data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E)](https://www.gavi.org/vaccineswork/common-antidepressant-shows-promise-easing-long-covid-fatigue) ## [Common antidepressant shows promise in easing Long COVID fatigue](https://www.gavi.org/vaccineswork/common-antidepressant-shows-promise-easing-long-covid-fatigue) 31 Mar 2026 4 min read [COVID-19](https://www.gavi.org/vaccineswork/tag/covid19)[Research summary](https://www.gavi.org/vaccineswork/tag/research-summary) *** ## Recommended for you ![Health worker prepares vaccine injection. Photo by Nappy on Unsplash](data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E) ## [Does obesity make vaccines less effective?](https://www.gavi.org/vaccineswork/does-obesity-make-vaccines-less-effective) 16 Apr 2026 5 min read ![A DHIS2 user explores a dashboard during refresher training in May 2022. Credit: PSI Laos](data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E) ## [Achieving immunisation impact through strengthened data systems](https://www.gavi.org/vaccineswork/achieving-immunisation-impact-through-strengthened-data-systems) 16 Apr 2026 7 min read ![Impression during the indoor excavation in the music hall of the Stadtcasino. 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Readable Markdown
### What is the research about? Around [one in eight people](https://www.gavi.org/vaccineswork/long-covid-affects-one-eight-says-lancet-study "Long COVID affects one in eight, says Lancet study") who get COVID-19 go on to develop Long COVID – post-infection symptoms persisting for at least a month. Reinfections of COVID-19 even in people who have been vaccinated have become increasingly common since the emergence of the Omicron variant. > ## The results also underline the importance of avoiding reinfection even if people are fully vaccinated and have recovered from Long COVID. So what effect does a reinfection have on someone who has already had COVID-19 and is now suffering from Long COVID? The UK charities Long COVID Kids and Long COVID Support conducted an internet survey to understand people’s experiences. ### What did the researchers do? The [survey](https://www.longcovidkids.org/post/a-world-first-effect-of-covid-reinfection-on-people-living-with-long-covid) was sent out to people with Long COVID in 30 countries including the UK, US, France and Canada and was open from 4 April 2022 to 19 June 2022. Responses were received from 484 adults and 112 children and young people who’d had at least two COVID-19 infections. #### Have you read? - [Mental health conditions raise risk of Long COVID](https://www.gavi.org/vaccineswork/mental-health-conditions-raises-risk-long-covid "Mental health conditions raise risk of Long COVID") - [Long COVID affects one in eight, says Lancet study](https://www.gavi.org/vaccineswork/long-covid-affects-one-eight-says-lancet-study "Long COVID affects one in eight, says Lancet study") - [Long COVID and the workplace: What employers could do better](https://www.gavi.org/vaccineswork/long-covid-and-workplace-what-employers-could-do-better "Long COVID and the workplace: What employers could do better") ### What did they find? The results were similar across adults and young people. As many as 89% of respondents first got Long COVID after their first infection, compared with 10% after the second infection, and just 1% after the third infection. Overwhelmingly, reinfection worsened the symptoms of Long COVID in most people who were still symptomatic. In those who still had Long COVID at the time of reinfection, 80% saw their symptoms worsen vs. 10% who saw their Long COVID symptoms improve. Around 85% saw old symptoms return or new additional symptoms vs. 10% who had a resolution or improvement of symptoms. In 60% of people who were in recovery or remission with Long COVID, reinfection caused a recurrence of Long COVID. ### What does this mean? The researchers say this is one of the first published studies of the effect of reinfection on Long COVID and their findings indicate the need for more investigations. The findings indicate that, as most people get Long COVID after their first infection, avoiding infection especially in children is critical. The results also underline the importance of avoiding reinfection even if people are fully vaccinated and have recovered from Long COVID.
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