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Raw Queries and Responses

1. Shard Calculation

Query:

Response:

Calculated Shard: 79 (from laksa175)

2. Crawled Status Check

Query:

curl -X POST \
  'http://laksa079.int.ahrefs:8124/' \
  -H 'Content-Type: text/plain' \
  -H 'X-ClickHouse-Database: crawler3' \
  -H 'Authorization: Basic YXBpOg==' \
  -d 'SELECT getAhrefsURLFromUnparsed(src_unparsed) AS found_url, ifNull(toUnixTimestamp(download_stamp), 0) AS crawl_time, ifNull(toUnixTimestamp(props_url_first_seen), 0) AS first_indexed_time, download_http_code AS http_code, src_unparsed AS src_unparsed, src_root_hash AS src_root_hash, history_drop_reason AS history_drop_reason, meta_title AS meta_title, meta_descriptions AS meta_descriptions, attrs_boilerpipe_text AS attrs_boilerpipe_text, attrs_markdown AS attrs_markdown, attrs_readable_markdown AS attrs_readable_markdown, meta_canonical AS meta_canonical FROM crawler3.page_info_local FINAL PREWHERE (src_root_hash, src_unparsed) IN ((getAhrefsRootHashFromUnparsed(getAhrefsUnparsedNoserviceFromURL(\'https://www.forhers.com/blog/how-to-get-antidepressants\')), getAhrefsUnparsedNoserviceFromURL(\'https://www.forhers.com/blog/how-to-get-antidepressants\'))) FORMAT JSONEachRow'

Response:

{"found_url":"https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants","crawl_time":1775969588,"first_indexed_time":1621016113,"http_code":200,"src_unparsed":"com,forhers!www,\/blog\/how-to-get-antidepressants s443","src_root_hash":"14475777380408463279","history_drop_reason":null,"meta_title":"How To Get Antidepressants | Take Care by Hers","meta_descriptions":["Feeling overwhelmed by depression? Learn how to get prescribed antidepressants by talking to a provider or navigating telemedicine platforms."],"attrs_boilerpipe_text":"When you’re depressed, seemingly small tasks or activities like brushing your teeth or grabbing after-work drinks can feel like an enormous hurdle. And mustering the strength — and vulnerability — to ask for help can feel nearly impossible. \nWhether you’ve new to these feelings or have been struggling with severe\ndepression\nfor years, you are not alone. Worldwide, nearly\n300 million\nadults suffer from this mental health disorder.\nFortunately, there are coping strategies and treatment plans that can help make living with depression less debilitating. Along with mental health resources like\ntalk therapy\n, antidepressant medication is one of the most\neffective\ntreatments healthcare providers recommend.\nSo if you’re wondering how to get depression medication, how exactly these medications work, or which kind of antidepressant could be right for you, keep reading.\n©\nOlga Moreira \/ Stocksy United. Model portrayal.\nWhile not as quick as adding a pair of shoes to your online shopping cart,\ngetting prescribed antidepressants\nisn’t as difficult as it may seem. You will need to get a prescription from a healthcare provider, though.\nIf you’re wondering where to get antidepressants, here are a few things you can do:\nTalk to your primary care provider.\nBased on your symptoms (and any coexisting medical conditions you might have), a primary care provider (PCP) can direct you to the right kind of medication. In addition to medication, your PCP may also recommend other forms of treatment, like\ngroup therapy\nor psychotherapy.\nGet a referral from a therapist.\nA\ntherapist\ncannot prescribe\ndepression medication\nin most states, but a psychiatrist or a nurse practitioner can. Making an appointment with a therapist is a good starting point because they can provide coping strategies based on your symptoms of depression and connect you with a professional who can write you a prescription.\nUtilize online telehealth platforms.\nIf you don’t feel like making the trip to the doctor’s office, you can also\nget antidepressants online\n.\nLastly,\nover-the-counter\nalternatives\nmight\noffer some benefits while you figure out if prescription medication is the right approach for you. A handful of the most popular ones include: \nSt. John’s wort\nOmega-3 fatty acids\n5-HTP\n(5-hydroxytryptophan)\nSAMe (S-adenosyl-L-methionine)\nWhile some research supports the effectiveness of the above\nsupplements\n, it’s important to note that there is still uncertainty about how effective they are as well as factors like dosage and drug interactions.\nIf you decide to dip your feet into the over-the-counter antidepressant pond, keep in mind: OTC antidepressants aren’t technically antidepressants, and they’re not a replacement for seeking professional help. Also, active ingredients in OTC supplements vary by brand and individual batches, delivering unpredictable results.\nWhen in doubt, always talk to a healthcare provider.\nIt’s totally normal to feel down sometimes, especially when you’re going through a rough patch, like a breakup or a job loss. But when those feelings become more intense and prolonged, you might start to wonder\nif you need antidepressants\n.\nAntidepressants are most\ncommonly\nprescribed for people who have\nmajor depressive disorder\n(MDD). MDD is described as an inability to experience pleasure or feeling depressed, moody, or\nsad\nevery day for at least two weeks accompanied by other symptoms such as low motivation and energy. They can also be used to treat\nanxiety\ndisorders and chronic pain, in some cases.\nFor many, the first step in talking about mental health struggles begins with a primary care provider. While you might associate your PCP as that person who gives you your annual physical or writes you a prescription when you get a sinus infection, they can actually be a great first stop on the train toward treatment. \nTo make a\ndiagnosis\n, a healthcare professional may ask if you’re experiencing symptoms of MDD,\nsuch as\n:\nSleep disruption\nWeight gain or\nweight loss\nTrouble making decisions\nFeelings of worthlessness\nSuicidal thoughts or frequent thoughts about death\nDecreased energy,\nfatigue\n, or feeling “slowed down”\nDepression enters some people’s lives in waves, depending on life circumstances. For others, the mental health condition might feel more like a\npermanent\nfixture — like a bad roommate who just won’t move out.\nYour healthcare provider will likely want to know how long you’ve been experiencing symptoms, their severity, and how your symptoms are presented before making an official diagnosis.\nNot sure how to start the conversation with your healthcare provider? Our guide on\nhow to ask your doctor for antidepressants\nhas some pointers to help you feel more confident in talking about your symptoms.\nDepression Medication\nDepression got you down?\nWhen people talk about antidepressants, it may seem like they’re referring to one kind of pill that magically works for everyone. The reality is there’s no one-size-fits-all treatment.\nThere are multiple types of antidepressants, and each person responds to them differently.\nHow long a person takes an antidepressant also varies. Some people may need antidepressants for a relatively short period (like while\ngrieving\nthe loss of a loved one), while those with chronic depression might need to stay on medication long-term. \nThese\nare the\nmost common antidepressants\nprescribed to patients:\nSelective serotonin reuptake inhibitors (\nSSRIs\n)\nSerotonin and norepinephrine reuptake inhibitors (SNRIs)\nTricyclic antidepressants\n(TCAs)\nBupropion (NDRI)\nLet’s get to know each one better. \nSSRIs\nSelective serotonin reuptake inhibitors target your serotonin levels. Many healthcare professionals\nconsider\nthem a first line of treatment for major depressive disorder as well as anxiety disorders.\nThe most commonly prescribed SSRIs\ninclude\n: \nEscitalopram\n(Lexapro\n®\n)\nFluoxetine\n(Prozac\n®\n)\nSertraline\n(Zoloft\n®\n)\nParoxetine\n(Paxil\n®\n) \nCitalopram\n(Celexa\n®\n)\nRx Available\nFeeling better is possible\nSNRIs\nSerotonin-norepinephrine reuptake inhibitors can also optimize serotonin activity, but they also target another neurotransmitter called norepinephrine.\nNorepinephrine, among other things,\nhelps\nregulate the sleep-wake cycle, stimulates the cardiovascular system, and is involved in the body’s fight-or-flight response.\nLow levels of norepinephrine are linked to symptoms like lethargy and poor concentration. By targeting both serotonin and norepinephrine, SNRI medication can be effective in treating anxiety\nand\ndepression.\nThe most commonly prescribed SNRIs are: \nVenlafaxine\n(Effexor XR\n®\n)\nDesvenlafaxine (Pristiq\n®\n)\nDuloxetine\n(Cymbalta\n®\n)\nMilnacipran (Savella\n®\n)\nLevomilnacipran (Fetzima\n®\n)\nTricyclic Antidepressants (TCAs)\nTricyclic antidepressants (TCAs) are a type of antidepressant developed in the 20th century. They’re among\nsome of the first\nprescription medications to be approved by the FDA.\nLots of people still use TCAs, though generally for issues unrelated to depression, because they’ve largely been replaced with other medications, like SSRIs and SNRIs. However, if you’re experiencing depression and those aforementioned meds aren’t cutting it, your healthcare provider might recommend TCAs as an alternative.\nBupropion\nBupropion is\nanother\nantidepressant used for the treatment of depression as well as\nseasonal affective disorder\n(SAD).\nIt’s an atypical antidepressant and belongs to a group of medications known as aminoketones. It impacts the way your body uses neurotransmitters like dopamine and norepinephrine to help regulate your moods. People with depression may have lower dopamine and norepinephrine levels, and bupropion works by increasing them.\nBupropion is sold under the brand names:\nWellbutrin\n®\nWellbutrin SR\n®\nWellbutrin XL\n®\n \nAplenzin\n®\nForfivo\n®\nXL (for major depressive disorder)\nYou might be surprised to learn that bupropion is also commonly used as a smoking cessation medication (sold under the brand name Zyban\n®\n).\nResearch shows\nit can help reduce tobacco cravings and withdrawal symptoms in ex-smokers. So, if you hear someone say they’re taking Wellbutrin\n®\nto kick their smoking habit, this is probably what they’re referring to.\nUnlike other antidepressants, bupropion is known to cause fewer and less severe\nadverse\nsymptoms, like drowsiness, weight gain, and sexual dysfunction. \nIt’s worth noting that these antidepressants don’t work instantly, and it may take some time for your body to adjust. Our\nfull antidepressant list\ngoes over additional medication options, as well as more in-depth explanations on how they work.\nEveryone’s mental health journey looks different. Your personal road to recovery may include antidepressants, and that’s perfectly normal.\nHere are a few key things to remember about depression medication:\nA healthcare provider can help.\nIn order to get antidepressants, you first need a prescription. A healthcare professional can ask you about your symptoms and determine\nwhich antidepressant is right for you\n.\nThere are many different types of antidepressants.\nThere’s no one-size-fits-all option when it comes to medication. What works for someone else may not work for you, and vice versa. Some common options include SSRIs, SNRIs, atypical antidepressants, and bupropion.\nYou have other support.\nSupport can include leaning on loved ones, connecting with friends, or spending time with a pet. It can also include\npsychiatry services\nor trying psychotherapy, like cognitive behavioral therapy (\nCBT\n). The important thing is finding a system that works for you. \nSeeking help for your depression can be overwhelming, but you’ve already taken the first step towards feeling better.\nReady for the next step? You can use our\nonline psychiatry\nplatform to connect with a licensed psychiatrist who can talk to you about your symptoms and even get you a prescription for antidepressants if you’re a fit.\nRelated Drug Comparisons\nAdderall vs. Lexapro\nCymbalta vs. Prozac\nBuspirone vs. Xanax\nCymbalta vs. Zoloft\nCymbalta vs. Lexapro\nLexapro vs. Prozac\nLexapro vs. Wellbutrin\nLexapro vs. Zoloft\nProzac vs. Zoloft\nSertraline vs. Zoloft\n12 Sources\nChu AN, et al. (2023). Selective Serotonin Reuptake Inhibitors.\nhttps:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554406\/\nFaquih AM, et al. (2019). A Review of Novel Antidepressants: A Guide for Clinicians.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6504013\/\nGelenberg AL, et al. (2006). The state of knowledge of chronic depression.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1470657\/\nHuecker MA, et al. (2023). Bupropion.\nhttps:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470212\/\nHussain LA, et al. (2023). Physiology, Noradrenergic Synapse.\nhttps:\/\/www.ncbi.nlm.nih.gov\/books\/NBK540977\/\nInformed Health. (2023). Depression: learn more – how effective are antidepressants?.\nhttps:\/\/www.ncbi.nlm.nih.gov\/books\/NBK361016\/\nJO Moraczewski, et al. (2023). Tricyclic Antidepressants.\nhttps:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557791\/\nNational Alliance on Mental Illness. (2024). Bupropion (Wellbutrin).\nhttps:\/\/www.nami.org\/about-mental-illness\/treatments\/mental-health-medications\/types-of-medication\/bupropion-wellbutrin\/\nNational Institute of Mental Health. (2024). Depression.\nhttps:\/\/www.nimh.nih.gov\/health\/topics\/depression\nNational Institute of Mental Health. (2023). Major Depression.\nhttps:\/\/www.nimh.nih.gov\/health\/statistics\/major-depression\nSheffler ZA, et al. (2023). Antidepressants.\nhttps:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538182\/\nU.S. Food & Drug Administration. (2014). Selective Serotonin Reuptake Inhibitors (SSRIs) Information.\nhttps:\/\/www.fda.gov\/drugs\/information-drug-class\/selective-serotonin-reuptake-inhibitors-ssris-information\nEditorial Standards\nHims & Hers has\nstrict sourcing guidelines\nto ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at\nblog@forhims.com\n!","attrs_markdown":"- [All](https:\/\/www.forhers.com\/blog)\n- [Weight Loss](https:\/\/www.forhers.com\/blog\/weight-loss)\n- [Menopause](https:\/\/www.forhers.com\/blog\/menopause)\n- [Mental Health](https:\/\/www.forhers.com\/blog\/mental-health)\n- [Hair](https:\/\/www.forhers.com\/blog\/hair)\n- [Skin](https:\/\/www.forhers.com\/blog\/skin)\n- [News](https:\/\/www.forhers.com\/blog\/news)\n\nContent\n\n1. [How to Get Prescribed Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#how-to-get-prescribed-antidepressants)\n2. [How to Ask a Doctor for Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#how-to-ask-a-doctor-for-antidepressants)\n3. [Common Types of Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#common-types-of-antidepressants)\n4. [Getting Antidepressants for Your Mental Health: Final Thoughts](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#getting-antidepressants-for-your-mental-health-final-thoughts)\n\n**Free** Mental Health Assessment\n\n[Start here](https:\/\/www.forhers.com\/c\/mh)\n\n1. [Home](https:\/\/www.forhers.com\/blog)\n2. [Mental Health](https:\/\/www.forhers.com\/blog\/mental-health)\n3. How To Get Antidepressants\n# How To Get Antidepressants\n\n![Daniel Z. Lieberman, MD](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit\/\/v1688592148\/dr-daniel.png)\n\nReviewed by [Daniel Z. Lieberman, MD](https:\/\/www.forhers.com\/medical-experts\/daniel-lieberman-dr)\n\nWritten by [Hadley Mendelsohn](https:\/\/www.forhers.com\/authors\/hadley-mendelsohn)\n\nPublished 05\/12\/2021\n\nUpdated 10\/15\/2024\n\nWhen you’re depressed, seemingly small tasks or activities like brushing your teeth or grabbing after-work drinks can feel like an enormous hurdle. And mustering the strength — and vulnerability — to ask for help can feel nearly impossible.\n\nWhether you’ve new to these feelings or have been struggling with severe [depression](https:\/\/www.forhers.com\/conditions\/depression) for years, you are not alone. Worldwide, nearly [300 million](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6504013\/) adults suffer from this mental health disorder.\n\nFortunately, there are coping strategies and treatment plans that can help make living with depression less debilitating. Along with mental health resources like [talk therapy](https:\/\/www.forhers.com\/blog\/what-is-talk-therapy), antidepressant medication is one of the most [effective](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK361016\/) treatments healthcare providers recommend.\n\nSo if you’re wondering how to get depression medication, how exactly these medications work, or which kind of antidepressant could be right for you, keep reading.\n\n![A woman researching how to get antidepressants on her laptop. ](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit\/v1756936797\/blog\/STOCKSY\/Hers\/Hers%20Mental%20Health\/Hers_Blog_Stocksy_Mentalhealth5160502.jpg)\n\n© Olga Moreira \/ Stocksy United. Model portrayal.\n\nContent\n\n1. [How to Get Prescribed Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#how-to-get-prescribed-antidepressants)\n2. [How to Ask a Doctor for Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#how-to-ask-a-doctor-for-antidepressants)\n3. [Common Types of Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#common-types-of-antidepressants)\n4. [Getting Antidepressants for Your Mental Health: Final Thoughts](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#getting-antidepressants-for-your-mental-health-final-thoughts)\n\n![How to Get Antidepressants](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit,w_0.5\/\/blog\/youtube\/horizontal_video_thumb_new\/B1V06.png)\n\n[How to Get Prescribed Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#how-to-get-prescribed-antidepressants)\n\nCopy Link\n\nWhile not as quick as adding a pair of shoes to your online shopping cart, [getting prescribed antidepressants](https:\/\/www.forhers.com\/blog\/who-can-prescribe-antidepressants) isn’t as difficult as it may seem. You will need to get a prescription from a healthcare provider, though.\n\nIf you’re wondering where to get antidepressants, here are a few things you can do:\n\n- **Talk to your primary care provider.** Based on your symptoms (and any coexisting medical conditions you might have), a primary care provider (PCP) can direct you to the right kind of medication. In addition to medication, your PCP may also recommend other forms of treatment, like [group therapy](https:\/\/www.forhers.com\/blog\/types-of-group-therapy) or psychotherapy.\n- **Get a referral from a therapist.** A [therapist](https:\/\/www.forhers.com\/blog\/finding-a-therapist) cannot prescribe [depression medication](https:\/\/www.forhers.com\/blog\/depression-medications) in most states, but a psychiatrist or a nurse practitioner can. Making an appointment with a therapist is a good starting point because they can provide coping strategies based on your symptoms of depression and connect you with a professional who can write you a prescription.\n- **Utilize online telehealth platforms.** If you don’t feel like making the trip to the doctor’s office, you can also [get antidepressants online](https:\/\/www.forhers.com\/psychiatry).\n\nLastly, [over-the-counter](https:\/\/www.forhers.com\/blog\/over-the-counter-antidepressants) alternatives *might* offer some benefits while you figure out if prescription medication is the right approach for you. A handful of the most popular ones include:\n\n- [St. John’s wort](https:\/\/www.forhers.com\/blog\/st-johns-wort-for-anxiety)\n- Omega-3 fatty acids\n- [5-HTP](https:\/\/www.forhers.com\/blog\/5-htp) (5-hydroxytryptophan)\n- SAMe (S-adenosyl-L-methionine)\n\nWhile some research supports the effectiveness of the above [supplements](https:\/\/www.forhers.com\/blog\/best-mood-boosting-supplements), it’s important to note that there is still uncertainty about how effective they are as well as factors like dosage and drug interactions.\n\nIf you decide to dip your feet into the over-the-counter antidepressant pond, keep in mind: OTC antidepressants aren’t technically antidepressants, and they’re not a replacement for seeking professional help. Also, active ingredients in OTC supplements vary by brand and individual batches, delivering unpredictable results.\n\nWhen in doubt, always talk to a healthcare provider.\n\n[How to Ask a Doctor for Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#how-to-ask-a-doctor-for-antidepressants)\n\nCopy Link\n\nIt’s totally normal to feel down sometimes, especially when you’re going through a rough patch, like a breakup or a job loss. But when those feelings become more intense and prolonged, you might start to wonder [if you need antidepressants](https:\/\/www.forhers.com\/blog\/do-i-need-antidepressants).\n\nAntidepressants are most [commonly](https:\/\/www.nimh.nih.gov\/health\/statistics\/major-depression) prescribed for people who have [major depressive disorder](https:\/\/www.forhers.com\/blog\/types-of-depression) (MDD). MDD is described as an inability to experience pleasure or feeling depressed, moody, or [sad](https:\/\/www.forhers.com\/blog\/why-do-i-get-sad-for-no-reason) every day for at least two weeks accompanied by other symptoms such as low motivation and energy. They can also be used to treat [anxiety](https:\/\/www.forhers.com\/conditions\/anxiety) disorders and chronic pain, in some cases.\n\nFor many, the first step in talking about mental health struggles begins with a primary care provider. While you might associate your PCP as that person who gives you your annual physical or writes you a prescription when you get a sinus infection, they can actually be a great first stop on the train toward treatment.\n\nTo make a [diagnosis](https:\/\/www.forhers.com\/blog\/can-you-self-diagnose-depression), a healthcare professional may ask if you’re experiencing symptoms of MDD, [such as](https:\/\/www.nimh.nih.gov\/health\/topics\/depression):\n\n- Sleep disruption\n- Weight gain or [weight loss](https:\/\/www.forhers.com\/blog\/depression-weight-loss)\n- Trouble making decisions\n- Feelings of worthlessness\n- Suicidal thoughts or frequent thoughts about death\n- Decreased energy, [fatigue](https:\/\/www.forhers.com\/blog\/mentally-exhaustion), or feeling “slowed down”\n\nDepression enters some people’s lives in waves, depending on life circumstances. For others, the mental health condition might feel more like a [permanent](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1470657\/) fixture — like a bad roommate who just won’t move out.\n\nYour healthcare provider will likely want to know how long you’ve been experiencing symptoms, their severity, and how your symptoms are presented before making an official diagnosis.\n\nNot sure how to start the conversation with your healthcare provider? Our guide on [how to ask your doctor for antidepressants](https:\/\/www.forhers.com\/blog\/how-to-ask-your-doctor-for-anxiety-medication) has some pointers to help you feel more confident in talking about your symptoms.\n\n[Depression Medication](https:\/\/www.forhers.com\/psychiatry)\n\n#### Depression got you down?\n\nGet treatment\n\nLearn more\n\n![Woman laying down with hands behind head](https:\/\/cloudinary.forhims.com\/image\/upload\/v1722957751\/2024%20Blog%20CTA%20Updates\/Hers\/Mental%20Health\/Blog-Hers-CVRUpdate-MH-CTA-DepressionGotYouDown.png)\n\n[Common Types of Antidepressants](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#common-types-of-antidepressants)\n\nCopy Link\n\nWhen people talk about antidepressants, it may seem like they’re referring to one kind of pill that magically works for everyone. The reality is there’s no one-size-fits-all treatment.\n\nThere are multiple types of antidepressants, and each person responds to them differently.\n\nHow long a person takes an antidepressant also varies. Some people may need antidepressants for a relatively short period (like while [grieving](https:\/\/www.forhers.com\/blog\/types-of-grief) the loss of a loved one), while those with chronic depression might need to stay on medication long-term.\n\n[These](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538182\/) are the [most common antidepressants](https:\/\/www.forhers.com\/blog\/common-antidepressants) prescribed to patients:\n\n- Selective serotonin reuptake inhibitors ([SSRIs](https:\/\/www.forhers.com\/blog\/ssri-drugs-overview-types))\n- Serotonin and norepinephrine reuptake inhibitors (SNRIs)\n- [Tricyclic antidepressants](https:\/\/www.forhers.com\/blog\/tricyclic-antidepressants-guide) (TCAs)\n- Bupropion (NDRI)\n\nLet’s get to know each one better.\n\n### SSRIs\nSelective serotonin reuptake inhibitors target your serotonin levels. Many healthcare professionals [consider](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554406\/#:~:text=Selective%20serotonin%20reuptake%20inhibitors%20\\(SSRIs,safety%2C%20efficacy%2C%20and%20tolerability.) them a first line of treatment for major depressive disorder as well as anxiety disorders.\n\nThe most commonly prescribed SSRIs [include](https:\/\/www.fda.gov\/drugs\/information-drug-class\/selective-serotonin-reuptake-inhibitors-ssris-information):\n\n- [Escitalopram](https:\/\/www.forhers.com\/psychiatry\/escitalopram) (Lexapro®)\n- [Fluoxetine](https:\/\/www.forhers.com\/psychiatry\/fluoxetine) (Prozac®)\n- [Sertraline](https:\/\/www.forhers.com\/psychiatry\/sertraline) (Zoloft®)\n- [Paroxetine](https:\/\/www.forhers.com\/psychiatry\/paroxetine) (Paxil®)\n- [Citalopram](https:\/\/www.forhers.com\/psychiatry\/citalopram) (Celexa®)\n\n[Rx Available](https:\/\/www.forhers.com\/psychiatry)\n\n#### Feeling better is possible\n\nStart now\n\nLearn more\n\n![Woman with blonde hair smiling](https:\/\/cloudinary.forhims.com\/image\/upload\/v1722957747\/2024%20Blog%20CTA%20Updates\/Hers\/Mental%20Health\/Blog-Hers-CVRUpdate-MH-CTA-FeelingBetterIsPossible.png)\n### SNRIs\nSerotonin-norepinephrine reuptake inhibitors can also optimize serotonin activity, but they also target another neurotransmitter called norepinephrine.\n\nNorepinephrine, among other things, [helps](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK540977\/) regulate the sleep-wake cycle, stimulates the cardiovascular system, and is involved in the body’s fight-or-flight response.\n\nLow levels of norepinephrine are linked to symptoms like lethargy and poor concentration. By targeting both serotonin and norepinephrine, SNRI medication can be effective in treating anxiety *and* depression.\n\nThe most commonly prescribed SNRIs are:\n\n- [Venlafaxine](https:\/\/www.hims.com\/psychiatry\/venlafaxine) (Effexor XR®)\n- Desvenlafaxine (Pristiq®)\n- [Duloxetine](https:\/\/www.hims.com\/psychiatry\/duloxetine) (Cymbalta®)\n- Milnacipran (Savella®)\n- Levomilnacipran (Fetzima®)\n### **Tricyclic Antidepressants (TCAs)**\nTricyclic antidepressants (TCAs) are a type of antidepressant developed in the 20th century. They’re among [some of the first](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557791\/) prescription medications to be approved by the FDA.\n\nLots of people still use TCAs, though generally for issues unrelated to depression, because they’ve largely been replaced with other medications, like SSRIs and SNRIs. However, if you’re experiencing depression and those aforementioned meds aren’t cutting it, your healthcare provider might recommend TCAs as an alternative.\n\n### Bupropion\nBupropion is [another](https:\/\/www.nami.org\/About-Mental-Illness\/Treatments\/Mental-Health-Medications\/Types-of-Medication\/Bupropion-\\(Wellbutrin\\)) antidepressant used for the treatment of depression as well as [seasonal affective disorder](https:\/\/www.forhers.com\/blog\/seasonal-depression-symptoms) (SAD).\n\nIt’s an atypical antidepressant and belongs to a group of medications known as aminoketones. It impacts the way your body uses neurotransmitters like dopamine and norepinephrine to help regulate your moods. People with depression may have lower dopamine and norepinephrine levels, and bupropion works by increasing them.\n\nBupropion is sold under the brand names:\n\n- Wellbutrin®\n- Wellbutrin SR®\n- [Wellbutrin XL®](https:\/\/www.forhers.com\/psychiatry\/bupropion)\n- Aplenzin®\n- Forfivo® XL (for major depressive disorder)\n\nYou might be surprised to learn that bupropion is also commonly used as a smoking cessation medication (sold under the brand name Zyban®). [Research shows](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470212\/#:~:text=Bupropion%20is%20an%20antidepressant%20medication,affective%20disorder%2C%20and%20smoking%20cessation.) it can help reduce tobacco cravings and withdrawal symptoms in ex-smokers. So, if you hear someone say they’re taking Wellbutrin® to kick their smoking habit, this is probably what they’re referring to.\n\nUnlike other antidepressants, bupropion is known to cause fewer and less severe [adverse](https:\/\/www.forhers.com\/blog\/bupropion-side-effects) symptoms, like drowsiness, weight gain, and sexual dysfunction.\n\nIt’s worth noting that these antidepressants don’t work instantly, and it may take some time for your body to adjust. Our [full antidepressant list](https:\/\/www.forhers.com\/blog\/full-list-antidepressants-ssri-snri) goes over additional medication options, as well as more in-depth explanations on how they work.\n\n[Depression Medication](https:\/\/www.forhers.com\/psychiatry)\n\n#### More for your mind\n\nStart now\n\nLearn more\n\n![Hers medication bottle](https:\/\/cloudinary.forhims.com\/image\/upload\/v1722957748\/2024%20Blog%20CTA%20Updates\/Hers\/Mental%20Health\/Blog-Hers-CVRUpdate-MH-CTA-MoreForYourMind.png)\n\n[Getting Antidepressants for Your Mental Health: Final Thoughts](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants#getting-antidepressants-for-your-mental-health-final-thoughts)\n\nCopy Link\n\nEveryone’s mental health journey looks different. Your personal road to recovery may include antidepressants, and that’s perfectly normal.\n\nHere are a few key things to remember about depression medication:\n\n- **A healthcare provider can help.** In order to get antidepressants, you first need a prescription. A healthcare professional can ask you about your symptoms and determine [which antidepressant is right for you](https:\/\/www.forhers.com\/blog\/which-antidepressant-is-best-for-me).\n- **There are many different types of antidepressants.** There’s no one-size-fits-all option when it comes to medication. What works for someone else may not work for you, and vice versa. Some common options include SSRIs, SNRIs, atypical antidepressants, and bupropion.\n- **You have other support.** Support can include leaning on loved ones, connecting with friends, or spending time with a pet. It can also include [psychiatry services](https:\/\/www.forhers.com\/mental-health) or trying psychotherapy, like cognitive behavioral therapy ([CBT](https:\/\/www.forhers.com\/blog\/what-is-cognitive-behavioral-therapy)). The important thing is finding a system that works for you.\n\nSeeking help for your depression can be overwhelming, but you’ve already taken the first step towards feeling better.\n\nReady for the next step? You can use our [online psychiatry](https:\/\/www.forhers.com\/psychiatry) platform to connect with a licensed psychiatrist who can talk to you about your symptoms and even get you a prescription for antidepressants if you’re a fit.\n\n### Related Drug Comparisons\n|   |   |\n|---|---|\n| [Adderall vs. Lexapro](https:\/\/www.forhers.com\/drugs\/compare\/adderall-vs-lexapro) | [Cymbalta vs. Prozac](https:\/\/www.forhers.com\/drugs\/compare\/cymbalta-vs-prozac) |\n| [Buspirone vs. Xanax](https:\/\/www.forhers.com\/drugs\/compare\/buspirone-vs-xanax) | [Cymbalta vs. Zoloft](https:\/\/www.forhers.com\/drugs\/compare\/cymbalta-vs-zoloft) |\n| [Cymbalta vs. Lexapro](https:\/\/www.forhers.com\/drugs\/compare\/cymbalta-vs-lexapro) | [Lexapro vs. Prozac](https:\/\/www.forhers.com\/drugs\/compare\/lexapro-vs-prozac) |\n| [Lexapro vs. Wellbutrin](https:\/\/www.forhers.com\/drugs\/compare\/lexapro-vs-wellbutrin) | [Lexapro vs. Zoloft](https:\/\/www.forhers.com\/drugs\/compare\/lexapro-vs-zoloft) |\n| [Prozac vs. Zoloft](https:\/\/www.forhers.com\/drugs\/compare\/prozac-vs-zoloft) | [Sertraline vs. Zoloft](https:\/\/www.forhers.com\/drugs\/compare\/sertraline-vs-zoloft) |\n\n### 12 Sources\n1. Chu AN, et al. (2023). Selective Serotonin Reuptake Inhibitors. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554406\/\n2. Faquih AM, et al. (2019). A Review of Novel Antidepressants: A Guide for Clinicians. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6504013\/\n3. Gelenberg AL, et al. (2006). The state of knowledge of chronic depression. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1470657\/\n4. Huecker MA, et al. (2023). Bupropion. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470212\/\n5. Hussain LA, et al. (2023). Physiology, Noradrenergic Synapse. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK540977\/\n6. Informed Health. (2023). Depression: learn more – how effective are antidepressants?. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK361016\/\n7. JO Moraczewski, et al. (2023). Tricyclic Antidepressants. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557791\/\n8. National Alliance on Mental Illness. (2024). Bupropion (Wellbutrin). https:\/\/www.nami.org\/about-mental-illness\/treatments\/mental-health-medications\/types-of-medication\/bupropion-wellbutrin\/\n9. National Institute of Mental Health. (2024). Depression. https:\/\/www.nimh.nih.gov\/health\/topics\/depression\n10. National Institute of Mental Health. (2023). Major Depression. https:\/\/www.nimh.nih.gov\/health\/statistics\/major-depression\n11. Sheffler ZA, et al. (2023). Antidepressants. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538182\/\n12. U.S. Food & Drug Administration. (2014). Selective Serotonin Reuptake Inhibitors (SSRIs) Information. https:\/\/www.fda.gov\/drugs\/information-drug-class\/selective-serotonin-reuptake-inhibitors-ssris-information\n\n###### Editorial Standards\nHims & Hers has [strict sourcing guidelines](https:\/\/www.forhers.com\/editorial-standards) to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [blog@forhims.com](mailto:blog@forhims.com)\\!\n\nThis article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards [here](https:\/\/www.forhers.com\/editorial-standards).\n\n[![Daniel Z. Lieberman, MD](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit\/\/v1688592148\/dr-daniel.png)](https:\/\/www.forhers.com\/medical-experts\/daniel-lieberman-dr)\n\n[Daniel Z. Lieberman, MD](https:\/\/www.forhers.com\/medical-experts\/daniel-lieberman-dr)\n\n## Education\n- Doctor of Medicine - [New York University Grossman School of Medicine](https:\/\/med.nyu.edu\/), 1992\n- Bachelor of Arts - [St. John’s College](https:\/\/www.sjc.edu\/), 1985\n## Training\n- Internship & Residency - [New York University Grossman School of Medicine](https:\/\/med.nyu.edu\/), 1996\n## Medical Licenses\n- District of Columbia, 1996\n- Maryland, 2022\n- Virginia, 2022\n## Board Certifications\n- [American Board of Psychiatry and Neurology](https:\/\/abpn.org\/), Psychiatry, 1997\n- [American Board of Psychiatry and Neurology](https:\/\/abpn.org\/), Addiction Psychiatry, 1998\n## Other Certificates & Certifications\n- [Stanford Online, AI in Healthcare Specialization Certificate](https:\/\/www.coursera.org\/account\/accomplishments\/specialization\/NZTXVOQOOPWX), 2025\n- [Stanford Online, Machine Learning Specialization Certificate](https:\/\/www.coursera.org\/account\/accomplishments\/specialization\/7F3HDP76SDK3), 2024\n## Affiliations & Memberships\n- [American Psychiatric Association](https:\/\/www.psychiatry.org\/)\n## Specialties & Areas of Focus\n- Mental Health\n## Years of Experience\n- 33\n## Previous Work Experience\n- Professor and Vice Chair - Department of Psychiatry and Behavioral Sciences, [George Washington University](https:\/\/www.gwu.edu\/), 1996–2022\n## Publications & Research\n- Title: A neurotransmitter approach to the trolley problem\n  - Published in: OBM Neurobiology\n  - Date: 2019\n  - URL: <https:\/\/www.lidsen.com\/journals\/neurobiology\/neurobiology-03-02-030>\n- Title: An automated internet application to help patients with bipolar disorder track social rhythm stabilization\n  - Published in: Psychiatric Services\n  - Date: 2011\n  - URL: <https:\/\/psychiatryonline.org\/doi\/10.1176\/ps.62.11.pss6211_1267>\n- Title: Enhancing adherence to mood charting with an online version of the NIMH Life Chart\n  - Published in: Annals of General Psychiatry\n  - Date: 2010\n  - URL: <https:\/\/annals-general-psychiatry.biomedcentral.com\/articles\/10.1186\/1744-859X-9-S1-S11>\n- Title: The role of gender in single versus married patients with bipolar disorder\n  - Published in: Comprehensive Psychiatry\n  - Date: 2010\n  - URL: <https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0010440X0900128X>\n- Title: Evaluation of the stability and validity of participant samples recruited over the Internet\n  - Published in: CyberPsychology and Behavior\n  - Date: 2008\n  - URL: <https:\/\/www.liebertpub.com\/doi\/10.1089\/cpb.2007.0254>\n- Title: Pathways to change: The effect of a Web application on treatment interest\n  - Published in: The American Journal on Addictions\n  - Date: 2008\n  - URL: <https:\/\/onlinelibrary.wiley.com\/doi\/10.1080\/10550490802138525>\n## Media Mentions & Features\n- Washington Post, [Why do passengers freak out on airplanes? Science might have the answer.](https:\/\/www.washingtonpost.com\/video\/national\/why-do-passengers-freak-out-on-airplanes-science-might-have-the-answer\/2018\/05\/11\/00592b2e-5531-11e8-a6d4-ca1d035642ce_video.html)\n- CNN, [The dangers of self-radicalization](https:\/\/www.cnn.com\/videos\/us\/2013\/05\/03\/lead-danger-of-self-radicalization-gwu-dan-lieberman.cnn)\n- Associated Press, [MillerCoors Tapping Into Millenials](http:\/\/youtu.be\/Jvv6VNjrgN0)\n- Time, [Hook Me Up: Are IV Clinics for You?](https:\/\/healthland.time.com\/2013\/01\/15\/hook-me-up-are-iv-clinics-for-you\/)\n- The Washington Post, [Holiday drinking can be hard on your health, but you can take precautions](https:\/\/www.washingtonpost.com\/national\/health-science\/holiday-drinking-can-be-hard-on-your-health-but-you-can-take-precautions\/2012\/12\/14\/e3543bae-42d0-11e2-8e70-e1993528222d_story.html)\n- Le Figaro (France), [Daniel Z. Lieberman: «La dopamine nous pousse à acheter en nous promettant le bonheur» (Daniel Z. Lieberman: “Dopamine drives us to buy by promising us happiness”)](https:\/\/www.lefigaro.fr\/sciences\/daniel-z-lieberman-la-dopamine-nous-pousse-a-acheter-en-nous-promettant-le-bonheur-20220211)\n- Men’s Health (Spain), [Cómo la dopamina influye en nuestro cerebro y determina nuestra vida (How dopamine influences our brain and determines our lives).](https:\/\/www.menshealth.com\/es\/salud-bienestar\/a38087703\/dopamina-determina-nuestra-vida\/)\n- El Mundo (Spain), [Dopamina, la sustancia que domina tu vida: a quién votas, con quién te acuestas y cuánto dinero ganas (Dopamine, the substance that dominates your life: who you vote for, who you sleep with and how much money you make)](https:\/\/www.elmundo.es\/papel\/historias\/2021\/10\/20\/6170319121efa04a3c8b4591.html)\n- Vice, [No One Owes You an Explanation About Their Vaccine](https:\/\/www.vice.com\/en\/article\/4ad9gw\/dont-ask-people-why-theyre-eligible-for-the-covid-vaccine)\n- CNBC, [The psychological reason it’s so hard to work today after the riot — and how to cope](https:\/\/www.cnbc.com\/2021\/01\/07\/how-to-cope-with-emotions-like-fear-and-anxiety-after-us-capitol-riot.html)\n- Today, [Are we ever going to shake hands again?](https:\/\/www.today.com\/health\/when-will-it-be-ok-shake-hands-how-should-you-t177562)\n- Business Insider, [The reason why we self-sabotage is because our brains are wired to resist the things we want most in life](https:\/\/www.businessinsider.com\/brain-resist-what-you-want-most-how-to-change-2019-10)\n- Forbes, [The Must-Read Brain Books Of 2018](https:\/\/www.forbes.com\/sites\/daviddisalvo\/2018\/12\/30\/the-must-read-brain-books-of-2018\/)\n- Daily Mail, [Why a day in the office wears you out: Sitting for hours using only our brains 'creates a chemical imbalance' - but these tips may help you feel more energized.](http:\/\/www.dailymail.co.uk\/health\/article-6140683\/Office-jobs-using-brains-tire-creating-chemical-imbalance-expert-explains.html)\n- U.S. News & World Report, [How Your Secrets Can Damage and Maybe Even Kill You](http:\/\/health.usnews.com\/wellness\/mind\/articles\/2017-06-26\/how-your-secrets-can-damage-and-maybe-even-kill-you)\n## Why I Practice Medicine\n- I practice medicine because I believe that mental health is the foundation of a meaningful life. When people suffer psychologically, it touches every part of their existence—from relationships to work to the simple ability to feel joy. Because it can be so difficult for people who are suffering to find good mental health care, my mission has been to expand access through technology, so that no one is left behind.\n## Hobbies & Interests\n- I like to write in my spare time. I’ve written two nonfiction titles, [Spellbound: Modern Science, Ancient Magic, and the Hidden Potential of the Unconscious Mind](https:\/\/www.amazon.com\/Spellbound-Science-Ancient-Potential-Unconscious\/dp\/1637741324) and the international bestseller, [The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity--and Will Determine the Fate of the Human Race](https:\/\/www.amazon.com\/Molecule-More-Chemical-Creativity_and-Determine\/dp\/1948836580)\n## Professional Website or Profile\n- danielzlieberman.com\n## LinkedIn\n- <https:\/\/www.linkedin.com\/in\/danielzlieberman\/>\n\n[Read more](https:\/\/www.forhers.com\/medical-experts\/daniel-lieberman-dr)\n\n#### Related Articles\n[Switching Antidepressants: What to Expect Written by Geoffrey C. Whittaker Published November 16, 2023](https:\/\/www.forhers.com\/blog\/switching-antidepressants-what-to-expect)\n\n[How to Get Antidepressants Without Insurance Written by Rachel Sacks Published April 30, 2025](https:\/\/www.forhers.com\/blog\/how-to-get-antidepressants-without-insurance)\n\n### Related Conditions\n[![Anxiety](https:\/\/cloudinary.forhims.com\/image\/upload\/v1723575819\/cms\/hers\/condition%20guides\/Hers-ConditionGuide-HubCard-MH-Anxiety.png)](https:\/\/www.forhers.com\/conditions\/anxiety)  [Anxiety](https:\/\/www.forhers.com\/conditions\/anxiety)\n\nAnxiety is common, but what is anxiety, really? It’s a feeling of worry, fear, or mental tension. If you have an anxiety disorder, this feeling can be overwhelming and may get worse over time. There are many different types of anxiety disorders and, luckily, many different treatments.\n\n[![Depression](https:\/\/cloudinary.forhims.com\/image\/upload\/v1723575818\/cms\/hers\/condition%20guides\/Hers-ConditionGuide-HubCard-MH-Depression.png)](https:\/\/www.forhers.com\/conditions\/depression)  [Depression](https:\/\/www.forhers.com\/conditions\/depression)\n\nDepression is a common but serious mental health disorder that can cause persistent feelings of sadness, worthlessness, or hopelessness. Its effects can be devastating. Depression can interfere with your ability to fulfill day-to-day responsibilities at home, at work, or in school.\n\n[![OCD](https:\/\/cloudinary.forhims.com\/image\/upload\/v1745787463\/cms\/hers\/condition%20guides\/Hers-ConditionGuide-HubCard-MH-OCD.png)](https:\/\/www.forhers.com\/conditions\/obsessive-compulsive-disorder-ocd)  [OCD](https:\/\/www.forhers.com\/conditions\/obsessive-compulsive-disorder-ocd)\n\nObsessive-compulsive disorder (OCD) is a mental health condition marked by recurring obsessive thoughts and difficult-to-control, compulsive behaviors.\n\n[![PTSD](https:\/\/cloudinary.forhims.com\/image\/upload\/v1733319240\/cms\/hers\/condition%20guides\/Hers-ConditionGuide-HubCard-MH-PTSD.png)](https:\/\/www.forhers.com\/conditions\/post-traumatic-stress-disorder-ptsd)  [PTSD](https:\/\/www.forhers.com\/conditions\/post-traumatic-stress-disorder-ptsd)\n\nBipolar disorder is a mental health condition characterized by unusually large shifts in an individual’s mood, concentration, energy and activity level.\n\n[![Bipolar Disorder](https:\/\/cloudinary.forhims.com\/image\/upload\/v1725452659\/cms\/hers\/condition%20guides\/Hers-ConditionGuide-HubCard-MH-BipolarDisorder_1.png)](https:\/\/www.forhers.com\/conditions\/bipolar-disorder)  [Bipolar Disorder](https:\/\/www.forhers.com\/conditions\/bipolar-disorder)\n\nBipolar disorder is a mental health condition characterized by unusually large shifts in an individual’s mood, concentration, energy and activity level.\n\n[![Premenstrual Dysphoric Disorder](https:\/\/cloudinary.forhims.com\/image\/upload\/v1738607287\/cms\/hers\/condition%20guides\/Hers-ConditionGuide-HubCard-MH-PMDD.png)](https:\/\/www.forhers.com\/conditions\/pmdd-premenstrual-dysphoric-disorder)  [Premenstrual Dysphoric Disorder](https:\/\/www.forhers.com\/conditions\/pmdd-premenstrual-dysphoric-disorder)\n\nObsessive-compulsive disorder (OCD) is a mental health condition marked by recurring obsessive thoughts and difficult-to-control, compulsive behaviors.\n\n###### Find relief for your symptoms\nLearn about your symptom score through clinically-backed assessments\n\n[Get started](https:\/\/www.forhers.com\/c\/mh)[Learn more](https:\/\/www.forhers.com\/mental-health)\n\n##### Explore\n[Mental Health](https:\/\/www.forhers.com\/mental-health \"Mental Health Treatments\")\n\n[Psychiatry](https:\/\/www.forhers.com\/psychiatry \"Anxiety and Depression Medication\")\n\n[Mental Health Content](https:\/\/www.forhers.com\/blog\/mental-health \"Mental Health Content\")\n\n[BMI Calculator](https:\/\/www.forhers.com\/tools\/bmi-calculator \"BMI Calculator\")\n\n[TDEE Calculator](https:\/\/www.forhers.com\/tools\/tdee-calculator \"TDEE Calculator\")\n\n[Calorie Deficit Calculator](https:\/\/www.forhers.com\/tools\/calorie-deficit-calculator \"Calorie Deficit Calculator\")\n\n[Protein Calculator](https:\/\/www.forhers.com\/tools\/protein-calculator \"Protein Calculator\")\n\n[Water Intake 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Tablets\")\n\n[![Image](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit,w_0.5\/Hims\/navigation\/nav-product-images\/MH_Optimized\/Hims-MH-Lexapro)Generic for Lexapro®Rx](https:\/\/www.forhers.com\/psychiatry\/escitalopram \"Escitalopram Tablets\")\n\n[![Image](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit,w_0.5\/Hims\/navigation\/nav-product-images\/Sex_Optimized\/Thumb-HH-MH-Propranolol-Single)PropranololRx](https:\/\/www.forhers.com\/well-being\/propranolol \"Propranolol Tablets\")\n\n[![Image](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit,w_0.5\/Hims\/navigation\/nav-product-images\/Sex_Optimized\/Thumb-HH-MH-FluoxetineSingle)Generic for Prozac®Rx](https:\/\/www.forhers.com\/psychiatry\/fluoxetine \"Fluoxetine Tablets\")\n\n[![Image](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit,w_0.5\/Hims\/navigation\/nav-product-images\/Sex_Optimized\/Thumb-HH-MH-Sertraline-Single)Generic for Zoloft®Rx](https:\/\/www.forhers.com\/psychiatry\/sertraline \"Sertraline Tablets\")\n\n[Explore All Treatments](https:\/\/www.forhers.com\/mental-health \"Mental Health Treatments\")\n\n##### Top blog resources\n[Who Can Prescribe Antidepressants?](https:\/\/www.forhers.com\/blog\/who-can-prescribe-antidepressants \"Who Can Prescribe Antidepressants?\")\n\n[Venlafaxine: Uses, Doses, and Potential Side Effects](https:\/\/www.forhers.com\/blog\/venlafaxine \"Venlafaxine: Uses, Doses, and Potential Side Effects\")\n\n[Sertraline Side Effects: Common, Severe & Long-Term](https:\/\/www.forhers.com\/blog\/a-complete-guide-to-sertraline-side-effects \"Sertraline Side Effects: Common, Severe & Long-Term\")\n\nDownload the free Hers app\n\n## Total care.\n## Totally different.\nDownload 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Hers\n[About Us](https:\/\/www.forhers.com\/about)\n\n[Take Care(It's our blog)](https:\/\/www.forhers.com\/blog)\n\n[How It Works](https:\/\/www.forhers.com\/about\/how-it-works)\n\n[Editorial Standards](https:\/\/www.forhers.com\/editorial-standards)\n\n[FAQs](https:\/\/support.hims.com\/hc\/en-us)\n\n[Investors](https:\/\/investors.forhims.com\/)\n\n### Careers\n[Professionals](https:\/\/www.forhers.com\/careers-professionals)\n\n[Providers](https:\/\/www.forhers.com\/careers-providers)\n\n### Connect\n[Customer Help Center](https:\/\/support.forhims.com\/hc\/en-us)\n\n[Press Center](https:\/\/news.hims.com\/)\n\n[visit hims.com](https:\/\/www.hims.com\/)","attrs_readable_markdown":"When you’re depressed, seemingly small tasks or activities like brushing your teeth or grabbing after-work drinks can feel like an enormous hurdle. And mustering the strength — and vulnerability — to ask for help can feel nearly impossible.\n\nWhether you’ve new to these feelings or have been struggling with severe [depression](https:\/\/www.forhers.com\/conditions\/depression) for years, you are not alone. Worldwide, nearly [300 million](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6504013\/) adults suffer from this mental health disorder.\n\nFortunately, there are coping strategies and treatment plans that can help make living with depression less debilitating. Along with mental health resources like [talk therapy](https:\/\/www.forhers.com\/blog\/what-is-talk-therapy), antidepressant medication is one of the most [effective](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK361016\/) treatments healthcare providers recommend.\n\nSo if you’re wondering how to get depression medication, how exactly these medications work, or which kind of antidepressant could be right for you, keep reading.\n\n![A woman researching how to get antidepressants on her laptop. ](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit\/v1756936797\/blog\/STOCKSY\/Hers\/Hers%20Mental%20Health\/Hers_Blog_Stocksy_Mentalhealth5160502.jpg) © Olga Moreira \/ Stocksy United. Model portrayal.\n\n![How to Get Antidepressants](https:\/\/www.forhers.com\/forhims\/image\/upload\/q_auto,f_auto,fl_lossy,c_limit,w_0.5\/\/blog\/youtube\/horizontal_video_thumb_new\/B1V06.png)\n\nWhile not as quick as adding a pair of shoes to your online shopping cart, [getting prescribed antidepressants](https:\/\/www.forhers.com\/blog\/who-can-prescribe-antidepressants) isn’t as difficult as it may seem. You will need to get a prescription from a healthcare provider, though.\n\nIf you’re wondering where to get antidepressants, here are a few things you can do:\n\n- **Talk to your primary care provider.** Based on your symptoms (and any coexisting medical conditions you might have), a primary care provider (PCP) can direct you to the right kind of medication. In addition to medication, your PCP may also recommend other forms of treatment, like [group therapy](https:\/\/www.forhers.com\/blog\/types-of-group-therapy) or psychotherapy.\n- **Get a referral from a therapist.** A [therapist](https:\/\/www.forhers.com\/blog\/finding-a-therapist) cannot prescribe [depression medication](https:\/\/www.forhers.com\/blog\/depression-medications) in most states, but a psychiatrist or a nurse practitioner can. Making an appointment with a therapist is a good starting point because they can provide coping strategies based on your symptoms of depression and connect you with a professional who can write you a prescription.\n- **Utilize online telehealth platforms.** If you don’t feel like making the trip to the doctor’s office, you can also [get antidepressants online](https:\/\/www.forhers.com\/psychiatry).\n\nLastly, [over-the-counter](https:\/\/www.forhers.com\/blog\/over-the-counter-antidepressants) alternatives *might* offer some benefits while you figure out if prescription medication is the right approach for you. A handful of the most popular ones include:\n\n- [St. John’s wort](https:\/\/www.forhers.com\/blog\/st-johns-wort-for-anxiety)\n- Omega-3 fatty acids\n- [5-HTP](https:\/\/www.forhers.com\/blog\/5-htp) (5-hydroxytryptophan)\n- SAMe (S-adenosyl-L-methionine)\n\nWhile some research supports the effectiveness of the above [supplements](https:\/\/www.forhers.com\/blog\/best-mood-boosting-supplements), it’s important to note that there is still uncertainty about how effective they are as well as factors like dosage and drug interactions.\n\nIf you decide to dip your feet into the over-the-counter antidepressant pond, keep in mind: OTC antidepressants aren’t technically antidepressants, and they’re not a replacement for seeking professional help. Also, active ingredients in OTC supplements vary by brand and individual batches, delivering unpredictable results.\n\nWhen in doubt, always talk to a healthcare provider.\n\nIt’s totally normal to feel down sometimes, especially when you’re going through a rough patch, like a breakup or a job loss. But when those feelings become more intense and prolonged, you might start to wonder [if you need antidepressants](https:\/\/www.forhers.com\/blog\/do-i-need-antidepressants).\n\nAntidepressants are most [commonly](https:\/\/www.nimh.nih.gov\/health\/statistics\/major-depression) prescribed for people who have [major depressive disorder](https:\/\/www.forhers.com\/blog\/types-of-depression) (MDD). MDD is described as an inability to experience pleasure or feeling depressed, moody, or [sad](https:\/\/www.forhers.com\/blog\/why-do-i-get-sad-for-no-reason) every day for at least two weeks accompanied by other symptoms such as low motivation and energy. They can also be used to treat [anxiety](https:\/\/www.forhers.com\/conditions\/anxiety) disorders and chronic pain, in some cases.\n\nFor many, the first step in talking about mental health struggles begins with a primary care provider. While you might associate your PCP as that person who gives you your annual physical or writes you a prescription when you get a sinus infection, they can actually be a great first stop on the train toward treatment.\n\nTo make a [diagnosis](https:\/\/www.forhers.com\/blog\/can-you-self-diagnose-depression), a healthcare professional may ask if you’re experiencing symptoms of MDD, [such as](https:\/\/www.nimh.nih.gov\/health\/topics\/depression):\n\n- Sleep disruption\n- Weight gain or [weight loss](https:\/\/www.forhers.com\/blog\/depression-weight-loss)\n- Trouble making decisions\n- Feelings of worthlessness\n- Suicidal thoughts or frequent thoughts about death\n- Decreased energy, [fatigue](https:\/\/www.forhers.com\/blog\/mentally-exhaustion), or feeling “slowed down”\n\nDepression enters some people’s lives in waves, depending on life circumstances. For others, the mental health condition might feel more like a [permanent](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1470657\/) fixture — like a bad roommate who just won’t move out.\n\nYour healthcare provider will likely want to know how long you’ve been experiencing symptoms, their severity, and how your symptoms are presented before making an official diagnosis.\n\nNot sure how to start the conversation with your healthcare provider? Our guide on [how to ask your doctor for antidepressants](https:\/\/www.forhers.com\/blog\/how-to-ask-your-doctor-for-anxiety-medication) has some pointers to help you feel more confident in talking about your symptoms.\n\n[Depression Medication](https:\/\/www.forhers.com\/psychiatry)\n\n#### Depression got you down?\n\n![Woman laying down with hands behind head](https:\/\/cloudinary.forhims.com\/image\/upload\/v1722957751\/2024%20Blog%20CTA%20Updates\/Hers\/Mental%20Health\/Blog-Hers-CVRUpdate-MH-CTA-DepressionGotYouDown.png)\n\nWhen people talk about antidepressants, it may seem like they’re referring to one kind of pill that magically works for everyone. The reality is there’s no one-size-fits-all treatment.\n\nThere are multiple types of antidepressants, and each person responds to them differently.\n\nHow long a person takes an antidepressant also varies. Some people may need antidepressants for a relatively short period (like while [grieving](https:\/\/www.forhers.com\/blog\/types-of-grief) the loss of a loved one), while those with chronic depression might need to stay on medication long-term.\n\n[These](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538182\/) are the [most common antidepressants](https:\/\/www.forhers.com\/blog\/common-antidepressants) prescribed to patients:\n\n- Selective serotonin reuptake inhibitors ([SSRIs](https:\/\/www.forhers.com\/blog\/ssri-drugs-overview-types))\n- Serotonin and norepinephrine reuptake inhibitors (SNRIs)\n- [Tricyclic antidepressants](https:\/\/www.forhers.com\/blog\/tricyclic-antidepressants-guide) (TCAs)\n- Bupropion (NDRI)\n\nLet’s get to know each one better.\n\n### SSRIs\nSelective serotonin reuptake inhibitors target your serotonin levels. Many healthcare professionals [consider](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554406\/#:~:text=Selective%20serotonin%20reuptake%20inhibitors%20\\(SSRIs,safety%2C%20efficacy%2C%20and%20tolerability.) them a first line of treatment for major depressive disorder as well as anxiety disorders.\n\nThe most commonly prescribed SSRIs [include](https:\/\/www.fda.gov\/drugs\/information-drug-class\/selective-serotonin-reuptake-inhibitors-ssris-information):\n\n- [Escitalopram](https:\/\/www.forhers.com\/psychiatry\/escitalopram) (Lexapro®)\n- [Fluoxetine](https:\/\/www.forhers.com\/psychiatry\/fluoxetine) (Prozac®)\n- [Sertraline](https:\/\/www.forhers.com\/psychiatry\/sertraline) (Zoloft®)\n- [Paroxetine](https:\/\/www.forhers.com\/psychiatry\/paroxetine) (Paxil®)\n- [Citalopram](https:\/\/www.forhers.com\/psychiatry\/citalopram) (Celexa®)\n\n[Rx Available](https:\/\/www.forhers.com\/psychiatry)\n\n#### Feeling better is possible\n\n![Woman with blonde hair smiling](https:\/\/cloudinary.forhims.com\/image\/upload\/v1722957747\/2024%20Blog%20CTA%20Updates\/Hers\/Mental%20Health\/Blog-Hers-CVRUpdate-MH-CTA-FeelingBetterIsPossible.png)\n### SNRIs\nSerotonin-norepinephrine reuptake inhibitors can also optimize serotonin activity, but they also target another neurotransmitter called norepinephrine.\n\nNorepinephrine, among other things, [helps](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK540977\/) regulate the sleep-wake cycle, stimulates the cardiovascular system, and is involved in the body’s fight-or-flight response.\n\nLow levels of norepinephrine are linked to symptoms like lethargy and poor concentration. By targeting both serotonin and norepinephrine, SNRI medication can be effective in treating anxiety *and* depression.\n\nThe most commonly prescribed SNRIs are:\n\n- [Venlafaxine](https:\/\/www.hims.com\/psychiatry\/venlafaxine) (Effexor XR®)\n- Desvenlafaxine (Pristiq®)\n- [Duloxetine](https:\/\/www.hims.com\/psychiatry\/duloxetine) (Cymbalta®)\n- Milnacipran (Savella®)\n- Levomilnacipran (Fetzima®)\n### **Tricyclic Antidepressants (TCAs)**\nTricyclic antidepressants (TCAs) are a type of antidepressant developed in the 20th century. They’re among [some of the first](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557791\/) prescription medications to be approved by the FDA.\n\nLots of people still use TCAs, though generally for issues unrelated to depression, because they’ve largely been replaced with other medications, like SSRIs and SNRIs. However, if you’re experiencing depression and those aforementioned meds aren’t cutting it, your healthcare provider might recommend TCAs as an alternative.\n\n### Bupropion\nBupropion is [another](https:\/\/www.nami.org\/About-Mental-Illness\/Treatments\/Mental-Health-Medications\/Types-of-Medication\/Bupropion-\\(Wellbutrin\\)) antidepressant used for the treatment of depression as well as [seasonal affective disorder](https:\/\/www.forhers.com\/blog\/seasonal-depression-symptoms) (SAD).\n\nIt’s an atypical antidepressant and belongs to a group of medications known as aminoketones. It impacts the way your body uses neurotransmitters like dopamine and norepinephrine to help regulate your moods. People with depression may have lower dopamine and norepinephrine levels, and bupropion works by increasing them.\n\nBupropion is sold under the brand names:\n\n- Wellbutrin®\n- Wellbutrin SR®\n- [Wellbutrin XL®](https:\/\/www.forhers.com\/psychiatry\/bupropion)\n- Aplenzin®\n- Forfivo® XL (for major depressive disorder)\n\nYou might be surprised to learn that bupropion is also commonly used as a smoking cessation medication (sold under the brand name Zyban®). [Research shows](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470212\/#:~:text=Bupropion%20is%20an%20antidepressant%20medication,affective%20disorder%2C%20and%20smoking%20cessation.) it can help reduce tobacco cravings and withdrawal symptoms in ex-smokers. So, if you hear someone say they’re taking Wellbutrin® to kick their smoking habit, this is probably what they’re referring to.\n\nUnlike other antidepressants, bupropion is known to cause fewer and less severe [adverse](https:\/\/www.forhers.com\/blog\/bupropion-side-effects) symptoms, like drowsiness, weight gain, and sexual dysfunction.\n\nIt’s worth noting that these antidepressants don’t work instantly, and it may take some time for your body to adjust. Our [full antidepressant list](https:\/\/www.forhers.com\/blog\/full-list-antidepressants-ssri-snri) goes over additional medication options, as well as more in-depth explanations on how they work.\n\n![Hers medication bottle](https:\/\/cloudinary.forhims.com\/image\/upload\/v1722957748\/2024%20Blog%20CTA%20Updates\/Hers\/Mental%20Health\/Blog-Hers-CVRUpdate-MH-CTA-MoreForYourMind.png)\n\nEveryone’s mental health journey looks different. Your personal road to recovery may include antidepressants, and that’s perfectly normal.\n\nHere are a few key things to remember about depression medication:\n\n- **A healthcare provider can help.** In order to get antidepressants, you first need a prescription. A healthcare professional can ask you about your symptoms and determine [which antidepressant is right for you](https:\/\/www.forhers.com\/blog\/which-antidepressant-is-best-for-me).\n- **There are many different types of antidepressants.** There’s no one-size-fits-all option when it comes to medication. What works for someone else may not work for you, and vice versa. Some common options include SSRIs, SNRIs, atypical antidepressants, and bupropion.\n- **You have other support.** Support can include leaning on loved ones, connecting with friends, or spending time with a pet. It can also include [psychiatry services](https:\/\/www.forhers.com\/mental-health) or trying psychotherapy, like cognitive behavioral therapy ([CBT](https:\/\/www.forhers.com\/blog\/what-is-cognitive-behavioral-therapy)). The important thing is finding a system that works for you.\n\nSeeking help for your depression can be overwhelming, but you’ve already taken the first step towards feeling better.\n\nReady for the next step? You can use our [online psychiatry](https:\/\/www.forhers.com\/psychiatry) platform to connect with a licensed psychiatrist who can talk to you about your symptoms and even get you a prescription for antidepressants if you’re a fit.\n\n### Related Drug Comparisons\n|   |   |\n|---|---|\n| [Adderall vs. Lexapro](https:\/\/www.forhers.com\/drugs\/compare\/adderall-vs-lexapro) | [Cymbalta vs. Prozac](https:\/\/www.forhers.com\/drugs\/compare\/cymbalta-vs-prozac) |\n| [Buspirone vs. Xanax](https:\/\/www.forhers.com\/drugs\/compare\/buspirone-vs-xanax) | [Cymbalta vs. Zoloft](https:\/\/www.forhers.com\/drugs\/compare\/cymbalta-vs-zoloft) |\n| [Cymbalta vs. Lexapro](https:\/\/www.forhers.com\/drugs\/compare\/cymbalta-vs-lexapro) | [Lexapro vs. Prozac](https:\/\/www.forhers.com\/drugs\/compare\/lexapro-vs-prozac) |\n| [Lexapro vs. Wellbutrin](https:\/\/www.forhers.com\/drugs\/compare\/lexapro-vs-wellbutrin) | [Lexapro vs. Zoloft](https:\/\/www.forhers.com\/drugs\/compare\/lexapro-vs-zoloft) |\n| [Prozac vs. Zoloft](https:\/\/www.forhers.com\/drugs\/compare\/prozac-vs-zoloft) | [Sertraline vs. Zoloft](https:\/\/www.forhers.com\/drugs\/compare\/sertraline-vs-zoloft) |\n\n12 Sources\n\n1. Chu AN, et al. (2023). Selective Serotonin Reuptake Inhibitors. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554406\/\n2. Faquih AM, et al. (2019). A Review of Novel Antidepressants: A Guide for Clinicians. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6504013\/\n3. Gelenberg AL, et al. (2006). The state of knowledge of chronic depression. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1470657\/\n4. Huecker MA, et al. (2023). Bupropion. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470212\/\n5. Hussain LA, et al. (2023). Physiology, Noradrenergic Synapse. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK540977\/\n6. Informed Health. (2023). Depression: learn more – how effective are antidepressants?. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK361016\/\n7. JO Moraczewski, et al. (2023). Tricyclic Antidepressants. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557791\/\n8. National Alliance on Mental Illness. (2024). Bupropion (Wellbutrin). https:\/\/www.nami.org\/about-mental-illness\/treatments\/mental-health-medications\/types-of-medication\/bupropion-wellbutrin\/\n9. National Institute of Mental Health. (2024). Depression. https:\/\/www.nimh.nih.gov\/health\/topics\/depression\n10. National Institute of Mental Health. (2023). Major Depression. https:\/\/www.nimh.nih.gov\/health\/statistics\/major-depression\n11. Sheffler ZA, et al. (2023). Antidepressants. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538182\/\n12. U.S. Food & Drug Administration. (2014). Selective Serotonin Reuptake Inhibitors (SSRIs) Information. https:\/\/www.fda.gov\/drugs\/information-drug-class\/selective-serotonin-reuptake-inhibitors-ssris-information\n\n###### Editorial Standards\nHims & Hers has [strict sourcing guidelines](https:\/\/www.forhers.com\/editorial-standards) to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [blog@forhims.com](mailto:blog@forhims.com)\\!","meta_canonical":null}

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Meta Title	How To Get Antidepressants \| Take Care by Hers
Meta Description	Feeling overwhelmed by depression? Learn how to get prescribed antidepressants by talking to a provider or navigating telemedicine platforms.
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Boilerpipe Text	When you’re depressed, seemingly small tasks or activities like brushing your teeth or grabbing after-work drinks can feel like an enormous hurdle. And mustering the strength — and vulnerability — to ask for help can feel nearly impossible. Whether you’ve new to these feelings or have been struggling with severe depression for years, you are not alone. Worldwide, nearly 300 million adults suffer from this mental health disorder. Fortunately, there are coping strategies and treatment plans that can help make living with depression less debilitating. Along with mental health resources like talk therapy , antidepressant medication is one of the most effective treatments healthcare providers recommend. So if you’re wondering how to get depression medication, how exactly these medications work, or which kind of antidepressant could be right for you, keep reading. © Olga Moreira / Stocksy United. Model portrayal. While not as quick as adding a pair of shoes to your online shopping cart, getting prescribed antidepressants isn’t as difficult as it may seem. You will need to get a prescription from a healthcare provider, though. If you’re wondering where to get antidepressants, here are a few things you can do: Talk to your primary care provider. Based on your symptoms (and any coexisting medical conditions you might have), a primary care provider (PCP) can direct you to the right kind of medication. In addition to medication, your PCP may also recommend other forms of treatment, like group therapy or psychotherapy. Get a referral from a therapist. A therapist cannot prescribe depression medication in most states, but a psychiatrist or a nurse practitioner can. Making an appointment with a therapist is a good starting point because they can provide coping strategies based on your symptoms of depression and connect you with a professional who can write you a prescription. Utilize online telehealth platforms. If you don’t feel like making the trip to the doctor’s office, you can also get antidepressants online . Lastly, over-the-counter alternatives might offer some benefits while you figure out if prescription medication is the right approach for you. A handful of the most popular ones include: St. John’s wort Omega-3 fatty acids 5-HTP (5-hydroxytryptophan) SAMe (S-adenosyl-L-methionine) While some research supports the effectiveness of the above supplements , it’s important to note that there is still uncertainty about how effective they are as well as factors like dosage and drug interactions. If you decide to dip your feet into the over-the-counter antidepressant pond, keep in mind: OTC antidepressants aren’t technically antidepressants, and they’re not a replacement for seeking professional help. Also, active ingredients in OTC supplements vary by brand and individual batches, delivering unpredictable results. When in doubt, always talk to a healthcare provider. It’s totally normal to feel down sometimes, especially when you’re going through a rough patch, like a breakup or a job loss. But when those feelings become more intense and prolonged, you might start to wonder if you need antidepressants . Antidepressants are most commonly prescribed for people who have major depressive disorder (MDD). MDD is described as an inability to experience pleasure or feeling depressed, moody, or sad every day for at least two weeks accompanied by other symptoms such as low motivation and energy. They can also be used to treat anxiety disorders and chronic pain, in some cases. For many, the first step in talking about mental health struggles begins with a primary care provider. While you might associate your PCP as that person who gives you your annual physical or writes you a prescription when you get a sinus infection, they can actually be a great first stop on the train toward treatment. To make a diagnosis , a healthcare professional may ask if you’re experiencing symptoms of MDD, such as : Sleep disruption Weight gain or weight loss Trouble making decisions Feelings of worthlessness Suicidal thoughts or frequent thoughts about death Decreased energy, fatigue , or feeling “slowed down” Depression enters some people’s lives in waves, depending on life circumstances. For others, the mental health condition might feel more like a permanent fixture — like a bad roommate who just won’t move out. Your healthcare provider will likely want to know how long you’ve been experiencing symptoms, their severity, and how your symptoms are presented before making an official diagnosis. Not sure how to start the conversation with your healthcare provider? Our guide on how to ask your doctor for antidepressants has some pointers to help you feel more confident in talking about your symptoms. Depression Medication Depression got you down? When people talk about antidepressants, it may seem like they’re referring to one kind of pill that magically works for everyone. The reality is there’s no one-size-fits-all treatment. There are multiple types of antidepressants, and each person responds to them differently. How long a person takes an antidepressant also varies. Some people may need antidepressants for a relatively short period (like while grieving the loss of a loved one), while those with chronic depression might need to stay on medication long-term. These are the most common antidepressants prescribed to patients: Selective serotonin reuptake inhibitors ( SSRIs ) Serotonin and norepinephrine reuptake inhibitors (SNRIs) Tricyclic antidepressants (TCAs) Bupropion (NDRI) Let’s get to know each one better. SSRIs Selective serotonin reuptake inhibitors target your serotonin levels. Many healthcare professionals consider them a first line of treatment for major depressive disorder as well as anxiety disorders. The most commonly prescribed SSRIs include : Escitalopram (Lexapro ® ) Fluoxetine (Prozac ® ) Sertraline (Zoloft ® ) Paroxetine (Paxil ® ) Citalopram (Celexa ® ) Rx Available Feeling better is possible SNRIs Serotonin-norepinephrine reuptake inhibitors can also optimize serotonin activity, but they also target another neurotransmitter called norepinephrine. Norepinephrine, among other things, helps regulate the sleep-wake cycle, stimulates the cardiovascular system, and is involved in the body’s fight-or-flight response. Low levels of norepinephrine are linked to symptoms like lethargy and poor concentration. By targeting both serotonin and norepinephrine, SNRI medication can be effective in treating anxiety and depression. The most commonly prescribed SNRIs are: Venlafaxine (Effexor XR ® ) Desvenlafaxine (Pristiq ® ) Duloxetine (Cymbalta ® ) Milnacipran (Savella ® ) Levomilnacipran (Fetzima ® ) Tricyclic Antidepressants (TCAs) Tricyclic antidepressants (TCAs) are a type of antidepressant developed in the 20th century. They’re among some of the first prescription medications to be approved by the FDA. Lots of people still use TCAs, though generally for issues unrelated to depression, because they’ve largely been replaced with other medications, like SSRIs and SNRIs. However, if you’re experiencing depression and those aforementioned meds aren’t cutting it, your healthcare provider might recommend TCAs as an alternative. Bupropion Bupropion is another antidepressant used for the treatment of depression as well as seasonal affective disorder (SAD). It’s an atypical antidepressant and belongs to a group of medications known as aminoketones. It impacts the way your body uses neurotransmitters like dopamine and norepinephrine to help regulate your moods. People with depression may have lower dopamine and norepinephrine levels, and bupropion works by increasing them. Bupropion is sold under the brand names: Wellbutrin ® Wellbutrin SR ® Wellbutrin XL ® Aplenzin ® Forfivo ® XL (for major depressive disorder) You might be surprised to learn that bupropion is also commonly used as a smoking cessation medication (sold under the brand name Zyban ® ). Research shows it can help reduce tobacco cravings and withdrawal symptoms in ex-smokers. So, if you hear someone say they’re taking Wellbutrin ® to kick their smoking habit, this is probably what they’re referring to. Unlike other antidepressants, bupropion is known to cause fewer and less severe adverse symptoms, like drowsiness, weight gain, and sexual dysfunction. It’s worth noting that these antidepressants don’t work instantly, and it may take some time for your body to adjust. Our full antidepressant list goes over additional medication options, as well as more in-depth explanations on how they work. Everyone’s mental health journey looks different. Your personal road to recovery may include antidepressants, and that’s perfectly normal. Here are a few key things to remember about depression medication: A healthcare provider can help. In order to get antidepressants, you first need a prescription. A healthcare professional can ask you about your symptoms and determine which antidepressant is right for you . There are many different types of antidepressants. There’s no one-size-fits-all option when it comes to medication. What works for someone else may not work for you, and vice versa. Some common options include SSRIs, SNRIs, atypical antidepressants, and bupropion. You have other support. Support can include leaning on loved ones, connecting with friends, or spending time with a pet. It can also include psychiatry services or trying psychotherapy, like cognitive behavioral therapy ( CBT ). The important thing is finding a system that works for you. Seeking help for your depression can be overwhelming, but you’ve already taken the first step towards feeling better. Ready for the next step? You can use our online psychiatry platform to connect with a licensed psychiatrist who can talk to you about your symptoms and even get you a prescription for antidepressants if you’re a fit. Related Drug Comparisons Adderall vs. Lexapro Cymbalta vs. Prozac Buspirone vs. Xanax Cymbalta vs. Zoloft Cymbalta vs. Lexapro Lexapro vs. Prozac Lexapro vs. Wellbutrin Lexapro vs. Zoloft Prozac vs. Zoloft Sertraline vs. Zoloft 12 Sources Chu AN, et al. (2023). Selective Serotonin Reuptake Inhibitors. https://www.ncbi.nlm.nih.gov/books/NBK554406/ Faquih AM, et al. (2019). A Review of Novel Antidepressants: A Guide for Clinicians. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504013/ Gelenberg AL, et al. (2006). The state of knowledge of chronic depression. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470657/ Huecker MA, et al. (2023). Bupropion. https://www.ncbi.nlm.nih.gov/books/NBK470212/ Hussain LA, et al. (2023). Physiology, Noradrenergic Synapse. https://www.ncbi.nlm.nih.gov/books/NBK540977/ Informed Health. (2023). Depression: learn more – how effective are antidepressants?. https://www.ncbi.nlm.nih.gov/books/NBK361016/ JO Moraczewski, et al. (2023). Tricyclic Antidepressants. https://www.ncbi.nlm.nih.gov/books/NBK557791/ National Alliance on Mental Illness. (2024). Bupropion (Wellbutrin). https://www.nami.org/about-mental-illness/treatments/mental-health-medications/types-of-medication/bupropion-wellbutrin/ National Institute of Mental Health. (2024). Depression. https://www.nimh.nih.gov/health/topics/depression National Institute of Mental Health. (2023). Major Depression. https://www.nimh.nih.gov/health/statistics/major-depression Sheffler ZA, et al. (2023). Antidepressants. https://www.ncbi.nlm.nih.gov/books/NBK538182/ U.S. Food & Drug Administration. (2014). Selective Serotonin Reuptake Inhibitors (SSRIs) Information. https://www.fda.gov/drugs/information-drug-class/selective-serotonin-reuptake-inhibitors-ssris-information Editorial Standards Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at blog@forhims.com !
Markdown	- [All](https://www.forhers.com/blog) - [Weight Loss](https://www.forhers.com/blog/weight-loss) - [Menopause](https://www.forhers.com/blog/menopause) - [Mental Health](https://www.forhers.com/blog/mental-health) - [Hair](https://www.forhers.com/blog/hair) - [Skin](https://www.forhers.com/blog/skin) - [News](https://www.forhers.com/blog/news) Content 1. [How to Get Prescribed Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#how-to-get-prescribed-antidepressants) 2. [How to Ask a Doctor for Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#how-to-ask-a-doctor-for-antidepressants) 3. [Common Types of Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#common-types-of-antidepressants) 4. [Getting Antidepressants for Your Mental Health: Final Thoughts](https://www.forhers.com/blog/how-to-get-antidepressants#getting-antidepressants-for-your-mental-health-final-thoughts) Free Mental Health Assessment [Start here](https://www.forhers.com/c/mh) 1. [Home](https://www.forhers.com/blog) 2. [Mental Health](https://www.forhers.com/blog/mental-health) 3. How To Get Antidepressants # How To Get Antidepressants ![Daniel Z. Lieberman, MD](https://www.forhers.com/forhims/image/upload/q_auto,f_auto,fl_lossy,c_limit//v1688592148/dr-daniel.png) Reviewed by [Daniel Z. Lieberman, MD](https://www.forhers.com/medical-experts/daniel-lieberman-dr) Written by [Hadley Mendelsohn](https://www.forhers.com/authors/hadley-mendelsohn) Published 05/12/2021 Updated 10/15/2024 When you’re depressed, seemingly small tasks or activities like brushing your teeth or grabbing after-work drinks can feel like an enormous hurdle. And mustering the strength — and vulnerability — to ask for help can feel nearly impossible. Whether you’ve new to these feelings or have been struggling with severe [depression](https://www.forhers.com/conditions/depression) for years, you are not alone. Worldwide, nearly [300 million](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504013/) adults suffer from this mental health disorder. Fortunately, there are coping strategies and treatment plans that can help make living with depression less debilitating. Along with mental health resources like [talk therapy](https://www.forhers.com/blog/what-is-talk-therapy), antidepressant medication is one of the most [effective](https://www.ncbi.nlm.nih.gov/books/NBK361016/) treatments healthcare providers recommend. So if you’re wondering how to get depression medication, how exactly these medications work, or which kind of antidepressant could be right for you, keep reading. ![A woman researching how to get antidepressants on her laptop. ](https://www.forhers.com/forhims/image/upload/q_auto,f_auto,fl_lossy,c_limit/v1756936797/blog/STOCKSY/Hers/Hers%20Mental%20Health/Hers_Blog_Stocksy_Mentalhealth5160502.jpg) © Olga Moreira / Stocksy United. Model portrayal. Content 1. [How to Get Prescribed Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#how-to-get-prescribed-antidepressants) 2. [How to Ask a Doctor for Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#how-to-ask-a-doctor-for-antidepressants) 3. [Common Types of Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#common-types-of-antidepressants) 4. [Getting Antidepressants for Your Mental Health: Final Thoughts](https://www.forhers.com/blog/how-to-get-antidepressants#getting-antidepressants-for-your-mental-health-final-thoughts) ![How to Get Antidepressants](https://www.forhers.com/forhims/image/upload/q_auto,f_auto,fl_lossy,c_limit,w_0.5//blog/youtube/horizontal_video_thumb_new/B1V06.png) [How to Get Prescribed Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#how-to-get-prescribed-antidepressants) Copy Link While not as quick as adding a pair of shoes to your online shopping cart, [getting prescribed antidepressants](https://www.forhers.com/blog/who-can-prescribe-antidepressants) isn’t as difficult as it may seem. You will need to get a prescription from a healthcare provider, though. If you’re wondering where to get antidepressants, here are a few things you can do: - Talk to your primary care provider. Based on your symptoms (and any coexisting medical conditions you might have), a primary care provider (PCP) can direct you to the right kind of medication. In addition to medication, your PCP may also recommend other forms of treatment, like [group therapy](https://www.forhers.com/blog/types-of-group-therapy) or psychotherapy. - Get a referral from a therapist. A [therapist](https://www.forhers.com/blog/finding-a-therapist) cannot prescribe [depression medication](https://www.forhers.com/blog/depression-medications) in most states, but a psychiatrist or a nurse practitioner can. Making an appointment with a therapist is a good starting point because they can provide coping strategies based on your symptoms of depression and connect you with a professional who can write you a prescription. - Utilize online telehealth platforms. If you don’t feel like making the trip to the doctor’s office, you can also [get antidepressants online](https://www.forhers.com/psychiatry). Lastly, [over-the-counter](https://www.forhers.com/blog/over-the-counter-antidepressants) alternatives might offer some benefits while you figure out if prescription medication is the right approach for you. A handful of the most popular ones include: - [St. John’s wort](https://www.forhers.com/blog/st-johns-wort-for-anxiety) - Omega-3 fatty acids - [5-HTP](https://www.forhers.com/blog/5-htp) (5-hydroxytryptophan) - SAMe (S-adenosyl-L-methionine) While some research supports the effectiveness of the above [supplements](https://www.forhers.com/blog/best-mood-boosting-supplements), it’s important to note that there is still uncertainty about how effective they are as well as factors like dosage and drug interactions. If you decide to dip your feet into the over-the-counter antidepressant pond, keep in mind: OTC antidepressants aren’t technically antidepressants, and they’re not a replacement for seeking professional help. Also, active ingredients in OTC supplements vary by brand and individual batches, delivering unpredictable results. When in doubt, always talk to a healthcare provider. [How to Ask a Doctor for Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#how-to-ask-a-doctor-for-antidepressants) Copy Link It’s totally normal to feel down sometimes, especially when you’re going through a rough patch, like a breakup or a job loss. But when those feelings become more intense and prolonged, you might start to wonder [if you need antidepressants](https://www.forhers.com/blog/do-i-need-antidepressants). Antidepressants are most [commonly](https://www.nimh.nih.gov/health/statistics/major-depression) prescribed for people who have [major depressive disorder](https://www.forhers.com/blog/types-of-depression) (MDD). MDD is described as an inability to experience pleasure or feeling depressed, moody, or [sad](https://www.forhers.com/blog/why-do-i-get-sad-for-no-reason) every day for at least two weeks accompanied by other symptoms such as low motivation and energy. They can also be used to treat [anxiety](https://www.forhers.com/conditions/anxiety) disorders and chronic pain, in some cases. For many, the first step in talking about mental health struggles begins with a primary care provider. While you might associate your PCP as that person who gives you your annual physical or writes you a prescription when you get a sinus infection, they can actually be a great first stop on the train toward treatment. To make a [diagnosis](https://www.forhers.com/blog/can-you-self-diagnose-depression), a healthcare professional may ask if you’re experiencing symptoms of MDD, [such as](https://www.nimh.nih.gov/health/topics/depression): - Sleep disruption - Weight gain or [weight loss](https://www.forhers.com/blog/depression-weight-loss) - Trouble making decisions - Feelings of worthlessness - Suicidal thoughts or frequent thoughts about death - Decreased energy, [fatigue](https://www.forhers.com/blog/mentally-exhaustion), or feeling “slowed down” Depression enters some people’s lives in waves, depending on life circumstances. For others, the mental health condition might feel more like a [permanent](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470657/) fixture — like a bad roommate who just won’t move out. Your healthcare provider will likely want to know how long you’ve been experiencing symptoms, their severity, and how your symptoms are presented before making an official diagnosis. Not sure how to start the conversation with your healthcare provider? Our guide on [how to ask your doctor for antidepressants](https://www.forhers.com/blog/how-to-ask-your-doctor-for-anxiety-medication) has some pointers to help you feel more confident in talking about your symptoms. [Depression Medication](https://www.forhers.com/psychiatry) #### Depression got you down? Get treatment Learn more ![Woman laying down with hands behind head](https://cloudinary.forhims.com/image/upload/v1722957751/2024%20Blog%20CTA%20Updates/Hers/Mental%20Health/Blog-Hers-CVRUpdate-MH-CTA-DepressionGotYouDown.png) [Common Types of Antidepressants](https://www.forhers.com/blog/how-to-get-antidepressants#common-types-of-antidepressants) Copy Link When people talk about antidepressants, it may seem like they’re referring to one kind of pill that magically works for everyone. The reality is there’s no one-size-fits-all treatment. There are multiple types of antidepressants, and each person responds to them differently. How long a person takes an antidepressant also varies. Some people may need antidepressants for a relatively short period (like while [grieving](https://www.forhers.com/blog/types-of-grief) the loss of a loved one), while those with chronic depression might need to stay on medication long-term. [These](https://www.ncbi.nlm.nih.gov/books/NBK538182/) are the [most common antidepressants](https://www.forhers.com/blog/common-antidepressants) prescribed to patients: - Selective serotonin reuptake inhibitors ([SSRIs](https://www.forhers.com/blog/ssri-drugs-overview-types)) - Serotonin and norepinephrine reuptake inhibitors (SNRIs) - [Tricyclic antidepressants](https://www.forhers.com/blog/tricyclic-antidepressants-guide) (TCAs) - Bupropion (NDRI) Let’s get to know each one better. ### SSRIs Selective serotonin reuptake inhibitors target your serotonin levels. Many healthcare professionals [consider](https://www.ncbi.nlm.nih.gov/books/NBK554406/#:~:text=Selective%20serotonin%20reuptake%20inhibitors%20\(SSRIs,safety%2C%20efficacy%2C%20and%20tolerability.) them a first line of treatment for major depressive disorder as well as anxiety disorders. The most commonly prescribed SSRIs [include](https://www.fda.gov/drugs/information-drug-class/selective-serotonin-reuptake-inhibitors-ssris-information): - [Escitalopram](https://www.forhers.com/psychiatry/escitalopram) (Lexapro®) - [Fluoxetine](https://www.forhers.com/psychiatry/fluoxetine) (Prozac®) - [Sertraline](https://www.forhers.com/psychiatry/sertraline) (Zoloft®) - [Paroxetine](https://www.forhers.com/psychiatry/paroxetine) (Paxil®) - [Citalopram](https://www.forhers.com/psychiatry/citalopram) (Celexa®) [Rx Available](https://www.forhers.com/psychiatry) #### Feeling better is possible Start now Learn more ![Woman with blonde hair smiling](https://cloudinary.forhims.com/image/upload/v1722957747/2024%20Blog%20CTA%20Updates/Hers/Mental%20Health/Blog-Hers-CVRUpdate-MH-CTA-FeelingBetterIsPossible.png) ### SNRIs Serotonin-norepinephrine reuptake inhibitors can also optimize serotonin activity, but they also target another neurotransmitter called norepinephrine. Norepinephrine, among other things, [helps](https://www.ncbi.nlm.nih.gov/books/NBK540977/) regulate the sleep-wake cycle, stimulates the cardiovascular system, and is involved in the body’s fight-or-flight response. Low levels of norepinephrine are linked to symptoms like lethargy and poor concentration. By targeting both serotonin and norepinephrine, SNRI medication can be effective in treating anxiety and depression. The most commonly prescribed SNRIs are: - [Venlafaxine](https://www.hims.com/psychiatry/venlafaxine) (Effexor XR®) - Desvenlafaxine (Pristiq®) - [Duloxetine](https://www.hims.com/psychiatry/duloxetine) (Cymbalta®) - Milnacipran (Savella®) - Levomilnacipran (Fetzima®) ### Tricyclic Antidepressants (TCAs) Tricyclic antidepressants (TCAs) are a type of antidepressant developed in the 20th century. They’re among [some of the first](https://www.ncbi.nlm.nih.gov/books/NBK557791/) prescription medications to be approved by the FDA. Lots of people still use TCAs, though generally for issues unrelated to depression, because they’ve largely been replaced with other medications, like SSRIs and SNRIs. However, if you’re experiencing depression and those aforementioned meds aren’t cutting it, your healthcare provider might recommend TCAs as an alternative. ### Bupropion Bupropion is [another](https://www.nami.org/About-Mental-Illness/Treatments/Mental-Health-Medications/Types-of-Medication/Bupropion-\(Wellbutrin\)) antidepressant used for the treatment of depression as well as [seasonal affective disorder](https://www.forhers.com/blog/seasonal-depression-symptoms) (SAD). It’s an atypical antidepressant and belongs to a group of medications known as aminoketones. It impacts the way your body uses neurotransmitters like dopamine and norepinephrine to help regulate your moods. People with depression may have lower dopamine and norepinephrine levels, and bupropion works by increasing them. Bupropion is sold under the brand names: - Wellbutrin® - Wellbutrin SR® - [Wellbutrin XL®](https://www.forhers.com/psychiatry/bupropion) - Aplenzin® - Forfivo® XL (for major depressive disorder) You might be surprised to learn that bupropion is also commonly used as a smoking cessation medication (sold under the brand name Zyban®). [Research shows](https://www.ncbi.nlm.nih.gov/books/NBK470212/#:~:text=Bupropion%20is%20an%20antidepressant%20medication,affective%20disorder%2C%20and%20smoking%20cessation.) it can help reduce tobacco cravings and withdrawal symptoms in ex-smokers. So, if you hear someone say they’re taking Wellbutrin® to kick their smoking habit, this is probably what they’re referring to. Unlike other antidepressants, bupropion is known to cause fewer and less severe [adverse](https://www.forhers.com/blog/bupropion-side-effects) symptoms, like drowsiness, weight gain, and sexual dysfunction. It’s worth noting that these antidepressants don’t work instantly, and it may take some time for your body to adjust. Our [full antidepressant list](https://www.forhers.com/blog/full-list-antidepressants-ssri-snri) goes over additional medication options, as well as more in-depth explanations on how they work. [Depression Medication](https://www.forhers.com/psychiatry) #### More for your mind Start now Learn more ![Hers medication bottle](https://cloudinary.forhims.com/image/upload/v1722957748/2024%20Blog%20CTA%20Updates/Hers/Mental%20Health/Blog-Hers-CVRUpdate-MH-CTA-MoreForYourMind.png) [Getting Antidepressants for Your Mental Health: Final Thoughts](https://www.forhers.com/blog/how-to-get-antidepressants#getting-antidepressants-for-your-mental-health-final-thoughts) Copy Link Everyone’s mental health journey looks different. Your personal road to recovery may include antidepressants, and that’s perfectly normal. Here are a few key things to remember about depression medication: - A healthcare provider can help. In order to get antidepressants, you first need a prescription. A healthcare professional can ask you about your symptoms and determine [which antidepressant is right for you](https://www.forhers.com/blog/which-antidepressant-is-best-for-me). - There are many different types of antidepressants. There’s no one-size-fits-all option when it comes to medication. What works for someone else may not work for you, and vice versa. Some common options include SSRIs, SNRIs, atypical antidepressants, and bupropion. - You have other support. Support can include leaning on loved ones, connecting with friends, or spending time with a pet. It can also include [psychiatry services](https://www.forhers.com/mental-health) or trying psychotherapy, like cognitive behavioral therapy ([CBT](https://www.forhers.com/blog/what-is-cognitive-behavioral-therapy)). The important thing is finding a system that works for you. Seeking help for your depression can be overwhelming, but you’ve already taken the first step towards feeling better. Ready for the next step? You can use our [online psychiatry](https://www.forhers.com/psychiatry) platform to connect with a licensed psychiatrist who can talk to you about your symptoms and even get you a prescription for antidepressants if you’re a fit. ### Related Drug Comparisons \| \| \| \|---\|---\| \| [Adderall vs. Lexapro](https://www.forhers.com/drugs/compare/adderall-vs-lexapro) \| [Cymbalta vs. Prozac](https://www.forhers.com/drugs/compare/cymbalta-vs-prozac) \| \| [Buspirone vs. Xanax](https://www.forhers.com/drugs/compare/buspirone-vs-xanax) \| [Cymbalta vs. Zoloft](https://www.forhers.com/drugs/compare/cymbalta-vs-zoloft) \| \| [Cymbalta vs. Lexapro](https://www.forhers.com/drugs/compare/cymbalta-vs-lexapro) \| [Lexapro vs. Prozac](https://www.forhers.com/drugs/compare/lexapro-vs-prozac) \| \| [Lexapro vs. Wellbutrin](https://www.forhers.com/drugs/compare/lexapro-vs-wellbutrin) \| [Lexapro vs. Zoloft](https://www.forhers.com/drugs/compare/lexapro-vs-zoloft) \| \| [Prozac vs. Zoloft](https://www.forhers.com/drugs/compare/prozac-vs-zoloft) \| [Sertraline vs. Zoloft](https://www.forhers.com/drugs/compare/sertraline-vs-zoloft) \| ### 12 Sources 1. Chu AN, et al. (2023). Selective Serotonin Reuptake Inhibitors. https://www.ncbi.nlm.nih.gov/books/NBK554406/ 2. Faquih AM, et al. (2019). A Review of Novel Antidepressants: A Guide for Clinicians. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504013/ 3. Gelenberg AL, et al. (2006). The state of knowledge of chronic depression. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470657/ 4. Huecker MA, et al. (2023). Bupropion. https://www.ncbi.nlm.nih.gov/books/NBK470212/ 5. Hussain LA, et al. (2023). Physiology, Noradrenergic Synapse. https://www.ncbi.nlm.nih.gov/books/NBK540977/ 6. Informed Health. (2023). Depression: learn more – how effective are antidepressants?. https://www.ncbi.nlm.nih.gov/books/NBK361016/ 7. JO Moraczewski, et al. (2023). Tricyclic Antidepressants. https://www.ncbi.nlm.nih.gov/books/NBK557791/ 8. National Alliance on Mental Illness. (2024). Bupropion (Wellbutrin). https://www.nami.org/about-mental-illness/treatments/mental-health-medications/types-of-medication/bupropion-wellbutrin/ 9. National Institute of Mental Health. (2024). Depression. https://www.nimh.nih.gov/health/topics/depression 10. National Institute of Mental Health. (2023). Major Depression. https://www.nimh.nih.gov/health/statistics/major-depression 11. Sheffler ZA, et al. (2023). Antidepressants. https://www.ncbi.nlm.nih.gov/books/NBK538182/ 12. U.S. Food & Drug Administration. (2014). Selective Serotonin Reuptake Inhibitors (SSRIs) Information. https://www.fda.gov/drugs/information-drug-class/selective-serotonin-reuptake-inhibitors-ssris-information ###### Editorial Standards Hims & Hers has [strict sourcing guidelines](https://www.forhers.com/editorial-standards) to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [blog@forhims.com](mailto:blog@forhims.com)\! This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards [here](https://www.forhers.com/editorial-standards). [![Daniel Z. Lieberman, MD](https://www.forhers.com/forhims/image/upload/q_auto,f_auto,fl_lossy,c_limit//v1688592148/dr-daniel.png)](https://www.forhers.com/medical-experts/daniel-lieberman-dr) [Daniel Z. Lieberman, MD](https://www.forhers.com/medical-experts/daniel-lieberman-dr) ## Education - Doctor of Medicine - [New York University Grossman School of Medicine](https://med.nyu.edu/), 1992 - Bachelor of Arts - [St. John’s College](https://www.sjc.edu/), 1985 ## Training - Internship & Residency - [New York University Grossman School of Medicine](https://med.nyu.edu/), 1996 ## Medical Licenses - District of Columbia, 1996 - Maryland, 2022 - Virginia, 2022 ## Board Certifications - [American Board of Psychiatry and Neurology](https://abpn.org/), Psychiatry, 1997 - [American Board of Psychiatry and Neurology](https://abpn.org/), Addiction Psychiatry, 1998 ## Other Certificates & Certifications - [Stanford Online, AI in Healthcare Specialization Certificate](https://www.coursera.org/account/accomplishments/specialization/NZTXVOQOOPWX), 2025 - [Stanford Online, Machine Learning Specialization Certificate](https://www.coursera.org/account/accomplishments/specialization/7F3HDP76SDK3), 2024 ## Affiliations & Memberships - [American Psychiatric Association](https://www.psychiatry.org/) ## Specialties & Areas of Focus - Mental Health ## Years of Experience - 33 ## Previous Work Experience - Professor and Vice Chair - Department of Psychiatry and Behavioral Sciences, [George Washington University](https://www.gwu.edu/), 1996–2022 ## Publications & Research - Title: A neurotransmitter approach to the trolley problem - Published in: OBM Neurobiology - Date: 2019 - URL: <https://www.lidsen.com/journals/neurobiology/neurobiology-03-02-030> - Title: An automated internet application to help patients with bipolar disorder track social rhythm stabilization - Published in: Psychiatric Services - Date: 2011 - URL: <https://psychiatryonline.org/doi/10.1176/ps.62.11.pss6211_1267> - Title: Enhancing adherence to mood charting with an online version of the NIMH Life Chart - Published in: Annals of General Psychiatry - Date: 2010 - URL: <https://annals-general-psychiatry.biomedcentral.com/articles/10.1186/1744-859X-9-S1-S11> - Title: The role of gender in single versus married patients with bipolar disorder - Published in: Comprehensive Psychiatry - Date: 2010 - URL: <https://www.sciencedirect.com/science/article/abs/pii/S0010440X0900128X> - Title: Evaluation of the stability and validity of participant samples recruited over the Internet - Published in: CyberPsychology and Behavior - Date: 2008 - URL: <https://www.liebertpub.com/doi/10.1089/cpb.2007.0254> - Title: Pathways to change: The effect of a Web application on treatment interest - Published in: The American Journal on Addictions - Date: 2008 - URL: <https://onlinelibrary.wiley.com/doi/10.1080/10550490802138525> ## Media Mentions & Features - Washington Post, [Why do passengers freak out on airplanes? Science might have the answer.](https://www.washingtonpost.com/video/national/why-do-passengers-freak-out-on-airplanes-science-might-have-the-answer/2018/05/11/00592b2e-5531-11e8-a6d4-ca1d035642ce_video.html) - CNN, [The dangers of self-radicalization](https://www.cnn.com/videos/us/2013/05/03/lead-danger-of-self-radicalization-gwu-dan-lieberman.cnn) - Associated Press, [MillerCoors Tapping Into Millenials](http://youtu.be/Jvv6VNjrgN0) - Time, [Hook Me Up: Are IV Clinics for You?](https://healthland.time.com/2013/01/15/hook-me-up-are-iv-clinics-for-you/) - The Washington Post, [Holiday drinking can be hard on your health, but you can take precautions](https://www.washingtonpost.com/national/health-science/holiday-drinking-can-be-hard-on-your-health-but-you-can-take-precautions/2012/12/14/e3543bae-42d0-11e2-8e70-e1993528222d_story.html) - Le Figaro (France), [Daniel Z. Lieberman: «La dopamine nous pousse à acheter en nous promettant le bonheur» (Daniel Z. Lieberman: “Dopamine drives us to buy by promising us happiness”)](https://www.lefigaro.fr/sciences/daniel-z-lieberman-la-dopamine-nous-pousse-a-acheter-en-nous-promettant-le-bonheur-20220211) - Men’s Health (Spain), [Cómo la dopamina influye en nuestro cerebro y determina nuestra vida (How dopamine influences our brain and determines our lives).](https://www.menshealth.com/es/salud-bienestar/a38087703/dopamina-determina-nuestra-vida/) - El Mundo (Spain), [Dopamina, la sustancia que domina tu vida: a quién votas, con quién te acuestas y cuánto dinero ganas (Dopamine, the substance that dominates your life: who you vote for, who you sleep with and how much money you make)](https://www.elmundo.es/papel/historias/2021/10/20/6170319121efa04a3c8b4591.html) - Vice, [No One Owes You an Explanation About Their Vaccine](https://www.vice.com/en/article/4ad9gw/dont-ask-people-why-theyre-eligible-for-the-covid-vaccine) - CNBC, [The psychological reason it’s so hard to work today after the riot — and how to cope](https://www.cnbc.com/2021/01/07/how-to-cope-with-emotions-like-fear-and-anxiety-after-us-capitol-riot.html) - Today, [Are we ever going to shake hands again?](https://www.today.com/health/when-will-it-be-ok-shake-hands-how-should-you-t177562) - Business Insider, [The reason why we self-sabotage is because our brains are wired to resist the things we want most in life](https://www.businessinsider.com/brain-resist-what-you-want-most-how-to-change-2019-10) - Forbes, [The Must-Read Brain Books Of 2018](https://www.forbes.com/sites/daviddisalvo/2018/12/30/the-must-read-brain-books-of-2018/) - Daily Mail, [Why a day in the office wears you out: Sitting for hours using only our brains 'creates a chemical imbalance' - but these tips may help you feel more energized.](http://www.dailymail.co.uk/health/article-6140683/Office-jobs-using-brains-tire-creating-chemical-imbalance-expert-explains.html) - U.S. News & World Report, [How Your Secrets Can Damage and Maybe Even Kill You](http://health.usnews.com/wellness/mind/articles/2017-06-26/how-your-secrets-can-damage-and-maybe-even-kill-you) ## Why I Practice Medicine - I practice medicine because I believe that mental health is the foundation of a meaningful life. When people suffer psychologically, it touches every part of their existence—from relationships to work to the simple ability to feel joy. Because it can be so difficult for people who are suffering to find good mental health care, my mission has been to expand access through technology, so that no one is left behind. ## Hobbies & Interests - I like to write in my spare time. I’ve written two nonfiction titles, [Spellbound: Modern Science, Ancient Magic, and the Hidden Potential of the Unconscious Mind](https://www.amazon.com/Spellbound-Science-Ancient-Potential-Unconscious/dp/1637741324) and the international bestseller, [The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity--and Will Determine the Fate of the Human Race](https://www.amazon.com/Molecule-More-Chemical-Creativity_and-Determine/dp/1948836580) ## Professional Website or Profile - danielzlieberman.com ## LinkedIn - <https://www.linkedin.com/in/danielzlieberman/> [Read more](https://www.forhers.com/medical-experts/daniel-lieberman-dr) #### Related Articles [Switching Antidepressants: What to Expect Written by Geoffrey C. Whittaker Published November 16, 2023](https://www.forhers.com/blog/switching-antidepressants-what-to-expect) [How to Get Antidepressants Without Insurance Written by Rachel Sacks Published April 30, 2025](https://www.forhers.com/blog/how-to-get-antidepressants-without-insurance) ### Related Conditions [![Anxiety](https://cloudinary.forhims.com/image/upload/v1723575819/cms/hers/condition%20guides/Hers-ConditionGuide-HubCard-MH-Anxiety.png)](https://www.forhers.com/conditions/anxiety) [Anxiety](https://www.forhers.com/conditions/anxiety) Anxiety is common, but what is anxiety, really? It’s a feeling of worry, fear, or mental tension. If you have an anxiety disorder, this feeling can be overwhelming and may get worse over time. There are many different types of anxiety disorders and, luckily, many different treatments. 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Readable Markdown	When you’re depressed, seemingly small tasks or activities like brushing your teeth or grabbing after-work drinks can feel like an enormous hurdle. And mustering the strength — and vulnerability — to ask for help can feel nearly impossible. Whether you’ve new to these feelings or have been struggling with severe [depression](https://www.forhers.com/conditions/depression) for years, you are not alone. Worldwide, nearly [300 million](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504013/) adults suffer from this mental health disorder. Fortunately, there are coping strategies and treatment plans that can help make living with depression less debilitating. Along with mental health resources like [talk therapy](https://www.forhers.com/blog/what-is-talk-therapy), antidepressant medication is one of the most [effective](https://www.ncbi.nlm.nih.gov/books/NBK361016/) treatments healthcare providers recommend. So if you’re wondering how to get depression medication, how exactly these medications work, or which kind of antidepressant could be right for you, keep reading. ![A woman researching how to get antidepressants on her laptop. ](https://www.forhers.com/forhims/image/upload/q_auto,f_auto,fl_lossy,c_limit/v1756936797/blog/STOCKSY/Hers/Hers%20Mental%20Health/Hers_Blog_Stocksy_Mentalhealth5160502.jpg) © Olga Moreira / Stocksy United. Model portrayal. ![How to Get Antidepressants](https://www.forhers.com/forhims/image/upload/q_auto,f_auto,fl_lossy,c_limit,w_0.5//blog/youtube/horizontal_video_thumb_new/B1V06.png) While not as quick as adding a pair of shoes to your online shopping cart, [getting prescribed antidepressants](https://www.forhers.com/blog/who-can-prescribe-antidepressants) isn’t as difficult as it may seem. You will need to get a prescription from a healthcare provider, though. If you’re wondering where to get antidepressants, here are a few things you can do: - Talk to your primary care provider. Based on your symptoms (and any coexisting medical conditions you might have), a primary care provider (PCP) can direct you to the right kind of medication. In addition to medication, your PCP may also recommend other forms of treatment, like [group therapy](https://www.forhers.com/blog/types-of-group-therapy) or psychotherapy. - Get a referral from a therapist. A [therapist](https://www.forhers.com/blog/finding-a-therapist) cannot prescribe [depression medication](https://www.forhers.com/blog/depression-medications) in most states, but a psychiatrist or a nurse practitioner can. Making an appointment with a therapist is a good starting point because they can provide coping strategies based on your symptoms of depression and connect you with a professional who can write you a prescription. - Utilize online telehealth platforms. If you don’t feel like making the trip to the doctor’s office, you can also [get antidepressants online](https://www.forhers.com/psychiatry). Lastly, [over-the-counter](https://www.forhers.com/blog/over-the-counter-antidepressants) alternatives might offer some benefits while you figure out if prescription medication is the right approach for you. A handful of the most popular ones include: - [St. John’s wort](https://www.forhers.com/blog/st-johns-wort-for-anxiety) - Omega-3 fatty acids - [5-HTP](https://www.forhers.com/blog/5-htp) (5-hydroxytryptophan) - SAMe (S-adenosyl-L-methionine) While some research supports the effectiveness of the above [supplements](https://www.forhers.com/blog/best-mood-boosting-supplements), it’s important to note that there is still uncertainty about how effective they are as well as factors like dosage and drug interactions. If you decide to dip your feet into the over-the-counter antidepressant pond, keep in mind: OTC antidepressants aren’t technically antidepressants, and they’re not a replacement for seeking professional help. Also, active ingredients in OTC supplements vary by brand and individual batches, delivering unpredictable results. When in doubt, always talk to a healthcare provider. It’s totally normal to feel down sometimes, especially when you’re going through a rough patch, like a breakup or a job loss. But when those feelings become more intense and prolonged, you might start to wonder [if you need antidepressants](https://www.forhers.com/blog/do-i-need-antidepressants). Antidepressants are most [commonly](https://www.nimh.nih.gov/health/statistics/major-depression) prescribed for people who have [major depressive disorder](https://www.forhers.com/blog/types-of-depression) (MDD). MDD is described as an inability to experience pleasure or feeling depressed, moody, or [sad](https://www.forhers.com/blog/why-do-i-get-sad-for-no-reason) every day for at least two weeks accompanied by other symptoms such as low motivation and energy. They can also be used to treat [anxiety](https://www.forhers.com/conditions/anxiety) disorders and chronic pain, in some cases. For many, the first step in talking about mental health struggles begins with a primary care provider. While you might associate your PCP as that person who gives you your annual physical or writes you a prescription when you get a sinus infection, they can actually be a great first stop on the train toward treatment. To make a [diagnosis](https://www.forhers.com/blog/can-you-self-diagnose-depression), a healthcare professional may ask if you’re experiencing symptoms of MDD, [such as](https://www.nimh.nih.gov/health/topics/depression): - Sleep disruption - Weight gain or [weight loss](https://www.forhers.com/blog/depression-weight-loss) - Trouble making decisions - Feelings of worthlessness - Suicidal thoughts or frequent thoughts about death - Decreased energy, [fatigue](https://www.forhers.com/blog/mentally-exhaustion), or feeling “slowed down” Depression enters some people’s lives in waves, depending on life circumstances. For others, the mental health condition might feel more like a [permanent](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470657/) fixture — like a bad roommate who just won’t move out. Your healthcare provider will likely want to know how long you’ve been experiencing symptoms, their severity, and how your symptoms are presented before making an official diagnosis. Not sure how to start the conversation with your healthcare provider? Our guide on [how to ask your doctor for antidepressants](https://www.forhers.com/blog/how-to-ask-your-doctor-for-anxiety-medication) has some pointers to help you feel more confident in talking about your symptoms. [Depression Medication](https://www.forhers.com/psychiatry) #### Depression got you down? ![Woman laying down with hands behind head](https://cloudinary.forhims.com/image/upload/v1722957751/2024%20Blog%20CTA%20Updates/Hers/Mental%20Health/Blog-Hers-CVRUpdate-MH-CTA-DepressionGotYouDown.png) When people talk about antidepressants, it may seem like they’re referring to one kind of pill that magically works for everyone. The reality is there’s no one-size-fits-all treatment. There are multiple types of antidepressants, and each person responds to them differently. How long a person takes an antidepressant also varies. Some people may need antidepressants for a relatively short period (like while [grieving](https://www.forhers.com/blog/types-of-grief) the loss of a loved one), while those with chronic depression might need to stay on medication long-term. [These](https://www.ncbi.nlm.nih.gov/books/NBK538182/) are the [most common antidepressants](https://www.forhers.com/blog/common-antidepressants) prescribed to patients: - Selective serotonin reuptake inhibitors ([SSRIs](https://www.forhers.com/blog/ssri-drugs-overview-types)) - Serotonin and norepinephrine reuptake inhibitors (SNRIs) - [Tricyclic antidepressants](https://www.forhers.com/blog/tricyclic-antidepressants-guide) (TCAs) - Bupropion (NDRI) Let’s get to know each one better. ### SSRIs Selective serotonin reuptake inhibitors target your serotonin levels. Many healthcare professionals [consider](https://www.ncbi.nlm.nih.gov/books/NBK554406/#:~:text=Selective%20serotonin%20reuptake%20inhibitors%20\(SSRIs,safety%2C%20efficacy%2C%20and%20tolerability.) them a first line of treatment for major depressive disorder as well as anxiety disorders. The most commonly prescribed SSRIs [include](https://www.fda.gov/drugs/information-drug-class/selective-serotonin-reuptake-inhibitors-ssris-information): - [Escitalopram](https://www.forhers.com/psychiatry/escitalopram) (Lexapro®) - [Fluoxetine](https://www.forhers.com/psychiatry/fluoxetine) (Prozac®) - [Sertraline](https://www.forhers.com/psychiatry/sertraline) (Zoloft®) - [Paroxetine](https://www.forhers.com/psychiatry/paroxetine) (Paxil®) - [Citalopram](https://www.forhers.com/psychiatry/citalopram) (Celexa®) [Rx Available](https://www.forhers.com/psychiatry) #### Feeling better is possible ![Woman with blonde hair smiling](https://cloudinary.forhims.com/image/upload/v1722957747/2024%20Blog%20CTA%20Updates/Hers/Mental%20Health/Blog-Hers-CVRUpdate-MH-CTA-FeelingBetterIsPossible.png) ### SNRIs Serotonin-norepinephrine reuptake inhibitors can also optimize serotonin activity, but they also target another neurotransmitter called norepinephrine. Norepinephrine, among other things, [helps](https://www.ncbi.nlm.nih.gov/books/NBK540977/) regulate the sleep-wake cycle, stimulates the cardiovascular system, and is involved in the body’s fight-or-flight response. Low levels of norepinephrine are linked to symptoms like lethargy and poor concentration. By targeting both serotonin and norepinephrine, SNRI medication can be effective in treating anxiety and depression. The most commonly prescribed SNRIs are: - [Venlafaxine](https://www.hims.com/psychiatry/venlafaxine) (Effexor XR®) - Desvenlafaxine (Pristiq®) - [Duloxetine](https://www.hims.com/psychiatry/duloxetine) (Cymbalta®) - Milnacipran (Savella®) - Levomilnacipran (Fetzima®) ### Tricyclic Antidepressants (TCAs) Tricyclic antidepressants (TCAs) are a type of antidepressant developed in the 20th century. They’re among [some of the first](https://www.ncbi.nlm.nih.gov/books/NBK557791/) prescription medications to be approved by the FDA. Lots of people still use TCAs, though generally for issues unrelated to depression, because they’ve largely been replaced with other medications, like SSRIs and SNRIs. However, if you’re experiencing depression and those aforementioned meds aren’t cutting it, your healthcare provider might recommend TCAs as an alternative. ### Bupropion Bupropion is [another](https://www.nami.org/About-Mental-Illness/Treatments/Mental-Health-Medications/Types-of-Medication/Bupropion-\(Wellbutrin\)) antidepressant used for the treatment of depression as well as [seasonal affective disorder](https://www.forhers.com/blog/seasonal-depression-symptoms) (SAD). It’s an atypical antidepressant and belongs to a group of medications known as aminoketones. It impacts the way your body uses neurotransmitters like dopamine and norepinephrine to help regulate your moods. People with depression may have lower dopamine and norepinephrine levels, and bupropion works by increasing them. Bupropion is sold under the brand names: - Wellbutrin® - Wellbutrin SR® - [Wellbutrin XL®](https://www.forhers.com/psychiatry/bupropion) - Aplenzin® - Forfivo® XL (for major depressive disorder) You might be surprised to learn that bupropion is also commonly used as a smoking cessation medication (sold under the brand name Zyban®). [Research shows](https://www.ncbi.nlm.nih.gov/books/NBK470212/#:~:text=Bupropion%20is%20an%20antidepressant%20medication,affective%20disorder%2C%20and%20smoking%20cessation.) it can help reduce tobacco cravings and withdrawal symptoms in ex-smokers. So, if you hear someone say they’re taking Wellbutrin® to kick their smoking habit, this is probably what they’re referring to. Unlike other antidepressants, bupropion is known to cause fewer and less severe [adverse](https://www.forhers.com/blog/bupropion-side-effects) symptoms, like drowsiness, weight gain, and sexual dysfunction. It’s worth noting that these antidepressants don’t work instantly, and it may take some time for your body to adjust. Our [full antidepressant list](https://www.forhers.com/blog/full-list-antidepressants-ssri-snri) goes over additional medication options, as well as more in-depth explanations on how they work. ![Hers medication bottle](https://cloudinary.forhims.com/image/upload/v1722957748/2024%20Blog%20CTA%20Updates/Hers/Mental%20Health/Blog-Hers-CVRUpdate-MH-CTA-MoreForYourMind.png) Everyone’s mental health journey looks different. Your personal road to recovery may include antidepressants, and that’s perfectly normal. Here are a few key things to remember about depression medication: - A healthcare provider can help. In order to get antidepressants, you first need a prescription. A healthcare professional can ask you about your symptoms and determine [which antidepressant is right for you](https://www.forhers.com/blog/which-antidepressant-is-best-for-me). - There are many different types of antidepressants. There’s no one-size-fits-all option when it comes to medication. What works for someone else may not work for you, and vice versa. Some common options include SSRIs, SNRIs, atypical antidepressants, and bupropion. - You have other support. Support can include leaning on loved ones, connecting with friends, or spending time with a pet. It can also include [psychiatry services](https://www.forhers.com/mental-health) or trying psychotherapy, like cognitive behavioral therapy ([CBT](https://www.forhers.com/blog/what-is-cognitive-behavioral-therapy)). The important thing is finding a system that works for you. Seeking help for your depression can be overwhelming, but you’ve already taken the first step towards feeling better. Ready for the next step? You can use our [online psychiatry](https://www.forhers.com/psychiatry) platform to connect with a licensed psychiatrist who can talk to you about your symptoms and even get you a prescription for antidepressants if you’re a fit. ### Related Drug Comparisons \| \| \| \|---\|---\| \| [Adderall vs. Lexapro](https://www.forhers.com/drugs/compare/adderall-vs-lexapro) \| [Cymbalta vs. Prozac](https://www.forhers.com/drugs/compare/cymbalta-vs-prozac) \| \| [Buspirone vs. Xanax](https://www.forhers.com/drugs/compare/buspirone-vs-xanax) \| [Cymbalta vs. Zoloft](https://www.forhers.com/drugs/compare/cymbalta-vs-zoloft) \| \| [Cymbalta vs. Lexapro](https://www.forhers.com/drugs/compare/cymbalta-vs-lexapro) \| [Lexapro vs. Prozac](https://www.forhers.com/drugs/compare/lexapro-vs-prozac) \| \| [Lexapro vs. Wellbutrin](https://www.forhers.com/drugs/compare/lexapro-vs-wellbutrin) \| [Lexapro vs. Zoloft](https://www.forhers.com/drugs/compare/lexapro-vs-zoloft) \| \| [Prozac vs. Zoloft](https://www.forhers.com/drugs/compare/prozac-vs-zoloft) \| [Sertraline vs. Zoloft](https://www.forhers.com/drugs/compare/sertraline-vs-zoloft) \| 12 Sources 1. Chu AN, et al. (2023). Selective Serotonin Reuptake Inhibitors. https://www.ncbi.nlm.nih.gov/books/NBK554406/ 2. Faquih AM, et al. (2019). A Review of Novel Antidepressants: A Guide for Clinicians. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504013/ 3. Gelenberg AL, et al. (2006). The state of knowledge of chronic depression. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470657/ 4. Huecker MA, et al. (2023). Bupropion. https://www.ncbi.nlm.nih.gov/books/NBK470212/ 5. Hussain LA, et al. (2023). Physiology, Noradrenergic Synapse. https://www.ncbi.nlm.nih.gov/books/NBK540977/ 6. Informed Health. (2023). Depression: learn more – how effective are antidepressants?. https://www.ncbi.nlm.nih.gov/books/NBK361016/ 7. JO Moraczewski, et al. (2023). Tricyclic Antidepressants. https://www.ncbi.nlm.nih.gov/books/NBK557791/ 8. National Alliance on Mental Illness. (2024). Bupropion (Wellbutrin). https://www.nami.org/about-mental-illness/treatments/mental-health-medications/types-of-medication/bupropion-wellbutrin/ 9. National Institute of Mental Health. (2024). Depression. https://www.nimh.nih.gov/health/topics/depression 10. National Institute of Mental Health. (2023). Major Depression. https://www.nimh.nih.gov/health/statistics/major-depression 11. Sheffler ZA, et al. (2023). Antidepressants. https://www.ncbi.nlm.nih.gov/books/NBK538182/ 12. U.S. Food & Drug Administration. (2014). Selective Serotonin Reuptake Inhibitors (SSRIs) Information. https://www.fda.gov/drugs/information-drug-class/selective-serotonin-reuptake-inhibitors-ssris-information ###### Editorial Standards Hims & Hers has [strict sourcing guidelines](https://www.forhers.com/editorial-standards) to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [blog@forhims.com](mailto:blog@forhims.com)\!
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