🕷️ Crawler Inspector

URL Lookup

Direct Parameter Lookup

Raw Queries and Responses

1. Shard Calculation

Query:
Response:
Calculated Shard: 79 (from laksa051)

2. Crawled Status Check

Query:
Response:

3. Robots.txt Check

Query:
Response:

4. Spam/Ban Check

Query:
Response:

5. Seen Status Check

ℹ️ Skipped - page is already crawled

đź“„
INDEXABLE
âś…
CRAWLED
15 days ago
🤖
ROBOTS ALLOWED

Page Info Filters

FilterStatusConditionDetails
HTTP statusPASSdownload_http_code = 200HTTP 200
Age cutoffPASSdownload_stamp > now() - 6 MONTH0.5 months ago
History dropPASSisNull(history_drop_reason)No drop reason
Spam/banPASSfh_dont_index != 1 AND ml_spam_score = 0ml_spam_score=0
CanonicalPASSmeta_canonical IS NULL OR = '' OR = src_unparsedNot set

Page Details

PropertyValue
URLhttps://www.forhers.com/blog/best-medication-for-depression
Last Crawled2026-04-12 06:05:02 (15 days ago)
First Indexed2022-02-07 05:09:29 (4 years ago)
HTTP Status Code200
Content
Meta TitleThe Best Medication for Depression | Take Care by Hers
Meta DescriptionIn addition to behavioral therapy, one way to approach to depression is medication. Read on to learn about some of the best medication for depression.
Meta Canonicalnull
Boilerpipe Text
If you are dealing with depression, you should know you are not alone — far from it, in fact. The 2019 National Survey on Drug Use and Health reported that more than 19 million adults in the U.S. experienced at least one major depressive episode during the previous year. In addition to behavioral therapy for depression , one way to approach treatment for depression is through medication.  A mental health professional can best help you figure out if you are depressed and will be able to guide you on treatment options — including possible medications.  Until then, you may be curious about some of the best medications for depression — including moderate depression, major depression or clinical depression.  Keep reading to learn about some of them. But, first, let us arm you with a bit more info about depression. A depressive disorder can be caused by a variety of factors. It’s often connected to low levels of certain neurotransmitters in your brain (like serotonin). Neuro-what? Neurotransmitters relay information between your neurons.  There are more than 100 different neurotransmitters, and a number of them are essential to how your brain and body function. There are a few different neurotransmitters that may be related to depression and its symptoms, including: Serotonin, which regulates things like your mood, hunger and sleep. Plus, it helps inhibit pain. There is research suggesting that some with depression have low levels of serotonin transmission in the brain. Norepinephrine , which boosts your blood pressure and constricts blood vessels. But it may have an effect on mood, too — like influencing your level of motivation. It is thought that norepinephrine has a hand in depression. Dopamine , a neurotransmitter you may have heard about. It has been connected to your perception of reality and also is involved in helping you feel motivated. Dopamine also plays a leading role in your brain’s reward system. Acetylcholine , which can help memory and is related to learning. It also aids in focusing on tasks. Gamma-aminobutyric acid (GABA) , which prevents certain types brain activity. Research points to people with depression possibly having lower levels of GABA. Antidepressant medication works by increasing levels of some neurotransmitters to help with symptoms of depression.  Wondering what the symptoms of depression look like? Common side effects include : Constant feelings of sadness, anxiety or hopelessness Feeling irritable, helpless or worthless Low energy or tiredness Changes in weight Difficulty sleeping Decreased appetite Thoughts of self-harm or suicide If you notice that you have some of the symptoms listed above, you should seek help from a mental health professional.  Whether you are dealing with mild or severe depression, a healthcare professional will be able to help identify the best course of treatment for you.  Therapy and medication are both commonly used to treat depression — often in conjunction with one another,  One thing to know about antidepressants: It can take four to eight weeks before you’ll see any improvement in your symptoms. There are many different types of medications that can treat depression. The four main types are selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors. A prescription drug called bupropion (also sold as the brand name Wellbutrin ® ) is often prescribed for depression, and often also used to treat seasonal affective disorder and depressive episodes associated with bipolar disorder.  Bupropion is considered an atypical antidepressant — which just means it doesn’t fall under the four main classes of antidepressants. In addition to buying bupropion online , the other most common types of antidepressants prescribed for depression are SSRIs and SNRIs.  Selective Serotonin Reuptake Inhibitors Selective serotonin reuptake inhibitors (SSRIs) are by far the most common type of antidepressant prescribed in the United States.  This is partially because they do not have as many drug interactions or side effects as older antidepressants. SSRIs increase serotonin levels in your brain by preventing your brain cells from reabsorbing existing serotonin. Here are some common SSRIs prescribed for varying degrees of depression—including severe depression:  Citalopram . Also sold as the brand name Celexa ® , this commonly prescribed oral antidepressant comes in tablet or liquid form. It’s also sometimes used to treat eating disorders, alcoholism and panic disorder. Escitalopram. Also available under the brand name Lexapro ® , this medication is prescribed to treat depression and generalized anxiety disorder (GAD). Fluoxetine . This popular medication (which is also sold under the brand name Prozac ® ) can be used to treat depression along with conditions like obsessive-compulsive disorder (OCD), panic disorder, and bulimia nervosa. You can buy fluoxetine online and other medications using Hers mental health services. Sertraline online . Also sold under the brand name Zoloft ® , this SSRI is commonly prescribed in the treatment of depression. Like fluoxetine, it is also used to treat OCD and panic disorder.  You can buy escitalopram online and other medications using our online mental health medication services. Serotonin–Norepinephrine Reuptake Inhibitors Serotonin–norepinephrine reuptake inhibitors (SNRIs) are another type of antidepressant.  They are similar to SSRIs in that they prevent the reabsorption of serotonin, but they also block the reabsorption of norepinephrine (another neurotransmitter), as well.  Low levels of norepinephrine have been linked to symptoms of depression — like difficulty concentrating and feeling sluggish. SNRIs that may be prescribed for depression include:  Desvenlafaxine, which is sold under the brand name Pristiq ® . This SNRI is not only used in the treatment of depression, it is also prescribed off-label to treat certain symptoms such as hot flashes in menopausal women. Duloxetine , which is sold under the brand name Cymbalta ® , is another SNRI that may help to  treat depression along with generalized anxiety disorder. Venlafaxine , which is sold under the brand name Effexor ® . This medication for depression also comes in an extended release form that may sometimes be prescribed to treat certain anxiety disorders.  You can buy venlafaxine online by using Hers online mental health service. There’s no magic equation when it comes to identifying the best antidepressant for you.  You can get depression medicine online to get diagnosed and determine if medication will be the best course of treatment.  From there, your healthcare provider will take into consideration your depression symptoms, other medical issues you may have and any other prescription drugs you are taking (as well as non-prescription meds). They may then prescribe you medication.  You should feel free to ask any questions you may have — like about common side effects, if there is potential risk involved, alternative treatments for depression, and more.  Research has shown that the different antidepressants work as well as one another. However, people react differently to the various medications.  For this reason, you may have to try a few different medications before landing on one that works best for you.  As previously mentioned, you should give the medication you're taking at least a month to see if it works.  If it doesn’t, it’s important not to stop taking your medication suddenly, as that can cause withdrawal symptoms.  Instead, speak to your healthcare provider to discuss the best approach for coming off one medication and trying another.  You should also call your healthcare provider immediately if you notice any bothersome side effects from taking prescription antidepressants.  There are a number of different medications used to treat depression. Two of the more common types are selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs). This is partially because they tend to have mild potential side effects.  It takes an average of four to six weeks for antidepressants to start working, so you will need to be patient to see if a specific medication works for you.   It’s also important to remember that you may need to try a few different options before settling on one that helps your depression.  Untreated depression is no way to live. To figure out the best medication to treat your depression, you’ll need to work closely with a mental healthcare professional.   Related Drug Comparisons Adderall vs. Lexapro Cymbalta vs. Prozac Buspirone vs. Xanax Cymbalta vs. Zoloft Cymbalta vs. Lexapro Lexapro vs. Prozac Lexapro vs. Wellbutrin Lexapro vs. Zoloft Prozac vs. Zoloft Sertraline vs. Zoloft 23 Sources Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. Major Depression. (2019, February). Retrieved from https://www.nimh.nih.gov/health/statistics/major-depression.shtml Hyman, S.E. (2005, March 8). Neurotransmitters. Current Biology. 15 (5), PR154-R158. Retrieved from https://www.cell.com/current-biology/comments/S0960-9822(05)00208-3 Cooper, J.R., (2001). Neurotransmitters. International Encyclopedia of the Social and Behavioral Sciences. Retrieved from https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/neurotransmitters What causes depression? (2019, June 24). Retrieved from https://www.health.harvard.edu/mind-and-mood/what-causes-depression Higley, M.J. & Picciotto, M.R. (2014, December). Neuromodulation by Acetylcholine: Examples from Schizophrenia and Depression. Current Opinion in Neurobiology. 29, 88–95. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268065/ Luscher, B., Shen, Q. & Sahir, N. (2011, April). The GABAergic Deficit Hypothesis of Major Depressive Disorder. Molecular Psychiatry. 16 (4), 383–406. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412149/ Depression of Women: 5 Things to Know. National Institute of Mental Health. Retrieved from https://www.nimh.nih.gov/health/publications/depression-in-women Depression. (2021). Retrieved from https://www.nimh.nih.gov/health/publications/depression/index.shtml What Meds Treat Depression? Mental Health America. Retrieved from https://screening.mhanational.org/content/what-meds-treat-depression/ Bupropion. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a695033.html Atypical Antidepressants. Mental Health America. Retrieved from https://screening.mhanational.org/content/atypical-antidepressants/ Commonly Prescribed Antidepressants and How They Work. Medline Plus. Retrieved from https://magazine.medlineplus.gov/article/commonly-prescribed-antidepressants-and-how-they-work Chu, A., Wadhwa, R., (2021, May 10). Selective Serotonin Reuptake Inhibitors. Stat Pearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK554406/ Citalopram. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a699001.html Highlights of Prescribing Information, Lexapro. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021323s052,021365s037lbl.pdf Highlights of Prescribing Information, Prozac. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/018936s109lbl.pdf Highlights of Prescribing Information, Zoloft. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019839s091lbl.pdf Sansone, R., Sansone, L., (2014). Serotonin Norepinephrine Reuptake Inhibitors: A Pharmacological Comparison. Innovations in Clinical Neuroscience. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008300/ Morel, C., Briley, M., (2011). The importance of norepinephrine in depression. Neuropsychiatric Disease and Treatment. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131098/ Desvenlafaxine. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a608022.html#:~:text=Desvenlafaxine%20is%20used%20to%20treat,that%20help%20maintain%20mental%20balance . Highlights of Prescribing Information, Cymbalta. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021427s053lbl.pdf Venlafaxine. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a694020.html Gartlehner, G., Hansen, R., Morgan, L., et al. (2007). Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression. Agency for Healthcare Research and Quality. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK83442/
Markdown
- [All](https://www.forhers.com/blog) - [Weight Loss](https://www.forhers.com/blog/weight-loss) - [Menopause](https://www.forhers.com/blog/menopause) - [Mental Health](https://www.forhers.com/blog/mental-health) - [Hair](https://www.forhers.com/blog/hair) - [Skin](https://www.forhers.com/blog/skin) - [News](https://www.forhers.com/blog/news) Content 1. [A Word on Depression](https://www.forhers.com/blog/best-medication-for-depression#a-word-on-depression) 2. [The Best Medications for Depression](https://www.forhers.com/blog/best-medication-for-depression#the-best-medications-for-depression) 3. [Finding the Best Depression Medicine](https://www.forhers.com/blog/best-medication-for-depression#finding-the-best-depression-medicine) 4. [The Best Medication for Your Depression](https://www.forhers.com/blog/best-medication-for-depression#the-best-medication-for-your-depression) **Free** Mental Health Assessment [Start here](https://www.forhers.com/c/mh) 1. [Home](https://www.forhers.com/blog) 2. [Mental Health](https://www.forhers.com/blog/mental-health) 3. The Best Medication for Depression # The Best Medication for Depression ![Katelyn Hagerty](https://www.forhers.com/forhims/image/upload/q_auto,f_auto,fl_lossy,c_limit//blog/authors/katelynheadshot.png) Reviewed by [Katelyn Hagerty, FNP](https://www.forhers.com/medical-experts/katelyn-hagerty-fnp) Written by Our Editorial Team Published 11/06/2021 Updated 11/07/2021 If you are dealing with depression, you should know you are not alone — far from it, in fact. The 2019 National Survey on Drug Use and Health [reported](https://www.nimh.nih.gov/health/statistics/major-depression.shtml) that more than 19 million adults in the U.S. experienced at least one major depressive episode during the previous year. In addition to [behavioral therapy for depression](https://www.forhers.com/blog/therapy-for-depression), one way to approach treatment for [depression](https://www.forhers.com/blog/dealing-with-depression) is through medication. A mental health professional can best help you figure out if you are depressed and will be able to guide you on treatment options — including possible medications. Until then, you may be curious about some of the best medications for depression — including moderate depression, major depression or clinical depression. Keep reading to learn about some of them. But, first, let us arm you with a bit more info about depression. Content 1. [A Word on Depression](https://www.forhers.com/blog/best-medication-for-depression#a-word-on-depression) 2. [The Best Medications for Depression](https://www.forhers.com/blog/best-medication-for-depression#the-best-medications-for-depression) 3. [Finding the Best Depression Medicine](https://www.forhers.com/blog/best-medication-for-depression#finding-the-best-depression-medicine) 4. [The Best Medication for Your Depression](https://www.forhers.com/blog/best-medication-for-depression#the-best-medication-for-your-depression) [**A Word on Depression**](https://www.forhers.com/blog/best-medication-for-depression#a-word-on-depression) Copy Link A depressive disorder can be caused by a variety of factors. It’s often connected to low levels of certain neurotransmitters in your brain (like serotonin). Neuro-what? Neurotransmitters [relay](https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/neurotransmitters) information between your neurons. There are more than 100 different neurotransmitters, and a number of them are [essential](https://www.ncbi.nlm.nih.gov/books/NBK10795/) to how your brain and body function. There are a few different neurotransmitters that may be related to depression and its symptoms, [including:](https://www.health.harvard.edu/mind-and-mood/what-causes-depression) - **Serotonin,** which regulates things like your mood, hunger and sleep. Plus, it helps inhibit pain. There is research suggesting that some with depression have low levels of serotonin transmission in the brain. - **Norepinephrine**, which boosts your blood pressure and constricts blood vessels. But it may have an effect on mood, too — like influencing your level of motivation. It is thought that norepinephrine has a hand in depression. - **Dopamine**, a neurotransmitter you may have heard about. It has been connected to your perception of reality and also is involved in helping you feel motivated. Dopamine also plays a leading role in your brain’s reward system. - **Acetylcholine**, which [can help memory](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268065/) and is related to learning. It also aids in [focusing](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268065/) on tasks. - **Gamma-aminobutyric acid (GABA)**, which prevents certain types brain activity.[Research](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412149/) points to people with depression possibly having lower levels of GABA. [Antidepressant medication](https://www.forhers.com/blog/depression-medications) works by increasing levels of some neurotransmitters to help with symptoms of depression. Wondering what the symptoms of depression look like? Common side effects [include](https://www.nimh.nih.gov/health/publications/depression): - Constant feelings of sadness, anxiety or hopelessness - Feeling irritable, helpless or worthless - Low energy or tiredness - Changes in weight - Difficulty sleeping - Decreased appetite - Thoughts of self-harm or suicide [**The Best Medications for Depression**](https://www.forhers.com/blog/best-medication-for-depression#the-best-medications-for-depression) Copy Link If you notice that you have some of the symptoms listed above, you should seek help from a mental health professional. Whether you are dealing with mild or severe depression, a healthcare professional will be able to help identify the best course of treatment for you. Therapy and medication are both commonly used to treat depression — often in conjunction with one another, One thing to know about antidepressants: It can take [four to eight weeks](https://www.nimh.nih.gov/health/publications/depression/index.shtml) before you’ll see any improvement in your symptoms. There are many different types of medications that can [treat](https://screening.mhanational.org/content/what-meds-treat-depression/) depression. The four main types are selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors. A prescription drug called [bupropion](https://www.forhers.com/drugs/info/buproprion) (also sold as the brand name Wellbutrin®) is often prescribed for depression, and often also used to treat seasonal affective disorder and depressive episodes [associated](https://medlineplus.gov/druginfo/meds/a695033.html) with bipolar disorder. Bupropion is considered an atypical antidepressant — which just means it doesn’t fall under the four main classes of antidepressants. In addition to [buying bupropion online](https://www.forhers.com/psychiatry/bupropion), the other most common types of antidepressants prescribed for depression are SSRIs and SNRIs. ### **Selective Serotonin Reuptake Inhibitors** [Selective serotonin reuptake inhibitors (SSRIs)](https://www.forhers.com/blog/ssri-drugs-overview-types) are by far the most common type of antidepressant [prescribed](https://magazine.medlineplus.gov/article/commonly-prescribed-antidepressants-and-how-they-work) in the United States. This is partially because they do not have as many drug interactions or side effects as older antidepressants. SSRIs increase serotonin levels in your brain by [preventing your brain cells](https://www.ncbi.nlm.nih.gov/books/NBK554406/) from reabsorbing existing serotonin. Here are some common SSRIs prescribed for varying degrees of depression—including severe depression: - [Citalopram](https://www.forhers.com/psychiatry/citalopram). Also sold as the brand name Celexa®, this commonly prescribed oral antidepressant comes in tablet or liquid form. It’s also sometimes used to treat eating disorders, alcoholism and panic disorder. - Escitalopram. Also available under the brand name Lexapro®, this medication is [prescribed](https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021323s052,021365s037lbl.pdf) to treat depression and generalized anxiety disorder (GAD). - Fluoxetine. This popular medication (which is also sold under the brand name Prozac®) can be [used](https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/018936s109lbl.pdf) to treat depression along with conditions like obsessive-compulsive disorder (OCD), panic disorder, and bulimia nervosa. You can [buy fluoxetine online](https://www.forhers.com/psychiatry/fluoxetine) and other medications using Hers mental health services. - [Sertraline online](https://www.forhers.com/psychiatry/sertraline). Also sold under the brand name Zoloft®, this SSRI is commonly [prescribed](https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019839s091lbl.pdf) in the treatment of depression. Like fluoxetine, it is also used to treat OCD and panic disorder. You can [buy escitalopram online](https://www.forhers.com/psychiatry/escitalopram) and other medications using our online [mental health medication](https://www.forhers.com/blog/mental-health-medication) services. ### **Serotonin–Norepinephrine Reuptake Inhibitors** Serotonin–norepinephrine reuptake inhibitors (SNRIs) are another type of antidepressant. They are similar to SSRIs in that they prevent the reabsorption of serotonin, but they also block the reabsorption of [norepinephrine](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008300/) (another neurotransmitter), as well. Low levels of norepinephrine have been linked to [symptoms](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131098/) of depression — like difficulty concentrating and feeling sluggish. SNRIs that may be prescribed for depression include: - Desvenlafaxine, which is sold under the brand name Pristiq®. This SNRI is not only [used](https://medlineplus.gov/druginfo/meds/a608022.html#:~:text=Desvenlafaxine%20is%20used%20to%20treat,that%20help%20maintain%20mental%20balance.) in the treatment of depression, it is also prescribed off-label to treat certain symptoms such as hot flashes in menopausal women. - [Duloxetine](https://www.forhers.com/psychiatry/duloxetine), which is sold under the brand name Cymbalta®, is another SNRI [that may help](https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021427s053lbl.pdf) to treat depression along with generalized anxiety disorder. - Venlafaxine, which is sold under the brand name Effexor®. This [medication](https://medlineplus.gov/druginfo/meds/a694020.html) for depression also comes in an extended release form that may sometimes be prescribed to treat certain anxiety disorders. You can [buy venlafaxine online](https://www.forhers.com/psychiatry/venlafaxine) by using Hers online mental health service. [**Finding the Best Depression Medicine**](https://www.forhers.com/blog/best-medication-for-depression#finding-the-best-depression-medicine) Copy Link There’s no magic equation when it comes to identifying the best antidepressant for you. You can [get depression medicine online](https://www.forhers.com/psychiatry) to get diagnosed and determine if medication will be the best course of treatment. From there, your healthcare provider will take into consideration your depression symptoms, other medical issues you may have and any other prescription drugs you are taking (as well as non-prescription meds). They may then prescribe you medication. You should feel free to ask any questions you may have — like about common side effects, if there is potential risk involved, alternative treatments for depression, and more. [Research](https://www.ncbi.nlm.nih.gov/books/NBK83442/) has shown that the different antidepressants work as well as one another. However, people react differently to the various medications. For this reason, you may have to try a few different medications before landing on one that works best for you. As previously mentioned, you should give the medication you're taking at least a month to see if it works. If it doesn’t, it’s important not to stop taking your medication suddenly, as that can cause withdrawal symptoms. Instead, speak to your healthcare provider to discuss the best approach for coming off one medication and trying another. You should also call your healthcare provider immediately if you notice any bothersome side effects from taking prescription antidepressants. [**The Best Medication for Your Depression**](https://www.forhers.com/blog/best-medication-for-depression#the-best-medication-for-your-depression) Copy Link There are a number of different medications used to treat depression. Two of the more common types are selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs). This is partially because they tend to have mild potential side effects. It takes an average of four to six weeks for antidepressants to start working, so you will need to be patient to see if a specific medication works for you. It’s also important to remember that you may need to try a few different options before settling on one that helps your depression. Untreated depression is no way to live. To figure out the best medication to treat your depression, you’ll need to work closely with a mental healthcare professional. ### Related Drug Comparisons | | | |---|---| | [Adderall vs. Lexapro](https://www.forhers.com/drugs/compare/adderall-vs-lexapro) | [Cymbalta vs. Prozac](https://www.forhers.com/drugs/compare/cymbalta-vs-prozac) | | [Buspirone vs. Xanax](https://www.forhers.com/drugs/compare/buspirone-vs-xanax) | [Cymbalta vs. Zoloft](https://www.forhers.com/drugs/compare/cymbalta-vs-zoloft) | | [Cymbalta vs. Lexapro](https://www.forhers.com/drugs/compare/cymbalta-vs-lexapro) | [Lexapro vs. Prozac](https://www.forhers.com/drugs/compare/lexapro-vs-prozac) | | [Lexapro vs. Wellbutrin](https://www.forhers.com/drugs/compare/lexapro-vs-wellbutrin) | [Lexapro vs. Zoloft](https://www.forhers.com/drugs/compare/lexapro-vs-zoloft) | | [Prozac vs. Zoloft](https://www.forhers.com/drugs/compare/prozac-vs-zoloft) | [Sertraline vs. Zoloft](https://www.forhers.com/drugs/compare/sertraline-vs-zoloft) | ### 23 Sources Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. 1. Major Depression. (2019, February). Retrieved from https://www.nimh.nih.gov/health/statistics/major-depression.shtml 2. Hyman, S.E. (2005, March 8). Neurotransmitters. Current Biology. 15 (5), PR154-R158. Retrieved from https://www.cell.com/current-biology/comments/S0960-9822(05)00208-3 3. Cooper, J.R., (2001). Neurotransmitters. International Encyclopedia of the Social and Behavioral Sciences. Retrieved from https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/neurotransmitters 4. What causes depression? (2019, June 24). Retrieved from https://www.health.harvard.edu/mind-and-mood/what-causes-depression 5. Higley, M.J. & Picciotto, M.R. (2014, December). Neuromodulation by Acetylcholine: Examples from Schizophrenia and Depression. Current Opinion in Neurobiology. 29, 88–95. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268065/ 6. Luscher, B., Shen, Q. & Sahir, N. (2011, April). The GABAergic Deficit Hypothesis of Major Depressive Disorder. Molecular Psychiatry. 16 (4), 383–406. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412149/ 7. Depression of Women: 5 Things to Know. National Institute of Mental Health. Retrieved from https://www.nimh.nih.gov/health/publications/depression-in-women 8. Depression. (2021). Retrieved from https://www.nimh.nih.gov/health/publications/depression/index.shtml 9. What Meds Treat Depression? Mental Health America. Retrieved from https://screening.mhanational.org/content/what-meds-treat-depression/ 10. Bupropion. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a695033.html 11. Atypical Antidepressants. Mental Health America. Retrieved from https://screening.mhanational.org/content/atypical-antidepressants/ 12. Commonly Prescribed Antidepressants and How They Work. Medline Plus. Retrieved from https://magazine.medlineplus.gov/article/commonly-prescribed-antidepressants-and-how-they-work 13. Chu, A., Wadhwa, R., (2021, May 10). Selective Serotonin Reuptake Inhibitors. Stat Pearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK554406/ 14. Citalopram. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a699001.html 15. Highlights of Prescribing Information, Lexapro. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda\_docs/label/2020/021323s052,021365s037lbl.pdf 16. Highlights of Prescribing Information, Prozac. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda\_docs/label/2020/018936s109lbl.pdf 17. Highlights of Prescribing Information, Zoloft. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda\_docs/label/2017/019839s091lbl.pdf 18. Sansone, R., Sansone, L., (2014). Serotonin Norepinephrine Reuptake Inhibitors: A Pharmacological Comparison. Innovations in Clinical Neuroscience. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008300/ 19. Morel, C., Briley, M., (2011). The importance of norepinephrine in depression. Neuropsychiatric Disease and Treatment. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131098/ 20. Desvenlafaxine. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a608022.html\#:~:text=Desvenlafaxine%20is%20used%20to%20treat,that%20help%20maintain%20mental%20balance. 21. Highlights of Prescribing Information, Cymbalta. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda\_docs/label/2020/021427s053lbl.pdf 22. Venlafaxine. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a694020.html 23. Gartlehner, G., Hansen, R., Morgan, L., et al. (2007). Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression. Agency for Healthcare Research and Quality. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK83442/ This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards [here](https://www.forhers.com/editorial-standards). #### Related Articles ### Related Conditions [![Anxiety](https://cloudinary.forhims.com/image/upload/v1723575819/cms/hers/condition%20guides/Hers-ConditionGuide-HubCard-MH-Anxiety.png)](https://www.forhers.com/conditions/anxiety) [Anxiety](https://www.forhers.com/conditions/anxiety) Anxiety is common, but what is anxiety, really? It’s a feeling of worry, fear, or mental tension. If you have an anxiety disorder, this feeling can be overwhelming and may get worse over time. There are many different types of anxiety disorders and, luckily, many different treatments. [![Depression](https://cloudinary.forhims.com/image/upload/v1723575818/cms/hers/condition%20guides/Hers-ConditionGuide-HubCard-MH-Depression.png)](https://www.forhers.com/conditions/depression) [Depression](https://www.forhers.com/conditions/depression) Depression is a common but serious mental health disorder that can cause persistent feelings of sadness, worthlessness, or hopelessness. Its effects can be devastating. Depression can interfere with your ability to fulfill day-to-day responsibilities at home, at work, or in school. [![OCD](https://cloudinary.forhims.com/image/upload/v1745787463/cms/hers/condition%20guides/Hers-ConditionGuide-HubCard-MH-OCD.png)](https://www.forhers.com/conditions/obsessive-compulsive-disorder-ocd) [OCD](https://www.forhers.com/conditions/obsessive-compulsive-disorder-ocd) Obsessive-compulsive disorder (OCD) is a mental health condition marked by recurring obsessive thoughts and difficult-to-control, compulsive behaviors. [![PTSD](https://cloudinary.forhims.com/image/upload/v1733319240/cms/hers/condition%20guides/Hers-ConditionGuide-HubCard-MH-PTSD.png)](https://www.forhers.com/conditions/post-traumatic-stress-disorder-ptsd) [PTSD](https://www.forhers.com/conditions/post-traumatic-stress-disorder-ptsd) Bipolar disorder is a mental health condition characterized by unusually large shifts in an individual’s mood, concentration, energy and activity level. [![Bipolar Disorder](https://cloudinary.forhims.com/image/upload/v1725452659/cms/hers/condition%20guides/Hers-ConditionGuide-HubCard-MH-BipolarDisorder_1.png)](https://www.forhers.com/conditions/bipolar-disorder) [Bipolar Disorder](https://www.forhers.com/conditions/bipolar-disorder) Bipolar disorder is a mental health condition characterized by unusually large shifts in an individual’s mood, concentration, energy and activity level. [![Premenstrual Dysphoric Disorder](https://cloudinary.forhims.com/image/upload/v1738607287/cms/hers/condition%20guides/Hers-ConditionGuide-HubCard-MH-PMDD.png)](https://www.forhers.com/conditions/pmdd-premenstrual-dysphoric-disorder) [Premenstrual Dysphoric Disorder](https://www.forhers.com/conditions/pmdd-premenstrual-dysphoric-disorder) Obsessive-compulsive disorder (OCD) is a mental health condition marked by recurring obsessive thoughts and difficult-to-control, compulsive behaviors. ###### Find relief for your symptoms Learn about your symptom score through clinically-backed assessments [Get started](https://www.forhers.com/c/mh)[Learn more](https://www.forhers.com/mental-health) ##### Explore [Mental Health](https://www.forhers.com/mental-health "Mental Health Treatments") [Psychiatry](https://www.forhers.com/psychiatry "Anxiety and Depression Medication") [Mental Health Content](https://www.forhers.com/blog/mental-health "Mental Health Content") [BMI Calculator](https://www.forhers.com/tools/bmi-calculator "BMI Calculator") [TDEE Calculator](https://www.forhers.com/tools/tdee-calculator "TDEE Calculator") [Calorie Deficit Calculator](https://www.forhers.com/tools/calorie-deficit-calculator "Calorie Deficit Calculator") [Protein Calculator](https://www.forhers.com/tools/protein-calculator "Protein Calculator") [Water Intake Calculator](https://www.forhers.com/tools/water-intake-calculator "Water Intake Calculator") [Drug Comparisons](https://www.forhers.com/drugs/compare "Drug Comparisons") [Quiz: Why Can't I Lose Weight?](https://www.forhers.com/tools/why-cant-i-lose-weight "Quiz: Why Can't I Lose Weight?") [Drugs & Medications](https://www.forhers.com/drugs/info "Drugs & Medications") ##### Condition Guides [Depression](https://www.forhers.com/conditions/depression "Depression") [Anxiety](https://www.forhers.com/conditions/anxiety "Anxiety") [See All Conditions](https://www.forhers.com/conditions "See All Conditions") ##### Popular [Generic for Wellbutrin XL®Rx](https://www.forhers.com/psychiatry/bupropion "Bupropion XL Tablets") [Generic for Lexapro®Rx](https://www.forhers.com/psychiatry/escitalopram "Escitalopram Tablets") [PropranololRx](https://www.forhers.com/well-being/propranolol "Propranolol Tablets") [Generic for Prozac®Rx](https://www.forhers.com/psychiatry/fluoxetine "Fluoxetine Tablets") [Generic for Zoloft®Rx](https://www.forhers.com/psychiatry/sertraline "Sertraline Tablets") [Explore All Treatments](https://www.forhers.com/mental-health "Mental Health Treatments") ##### Top blog resources [Who Can Prescribe Antidepressants?](https://www.forhers.com/blog/who-can-prescribe-antidepressants "Who Can Prescribe Antidepressants?") [Venlafaxine: Uses, Doses, and Potential Side Effects](https://www.forhers.com/blog/venlafaxine "Venlafaxine: Uses, Doses, and Potential Side Effects") [Sertraline Side Effects: Common, Severe & Long-Term](https://www.forhers.com/blog/a-complete-guide-to-sertraline-side-effects "Sertraline Side Effects: Common, Severe & Long-Term") [Switching Antidepressants: What to Expect Written by Geoffrey C. Whittaker Published November 16, 2023](https://www.forhers.com/blog/switching-antidepressants-what-to-expect) [How to Get Antidepressants Without Insurance Written by Rachel Sacks Published April 30, 2025](https://www.forhers.com/blog/how-to-get-antidepressants-without-insurance) Download the free Hers app ## Total care. ## Totally different. Download the app For iOS and Android ![Download the free Hers app](https://www.forhers.com/forhims/image/upload/hers/global/footer-app_static-hers) ### Learn [Labs](https://www.forhers.com/labs) [Weight Loss](https://www.forhers.com/weight-loss) [Menopause](https://www.forhers.com/learn/menopause) [Hair Loss](https://www.forhers.com/blog/hair) [Mental Health](https://www.forhers.com/blog/mental-health%20) [Skincare](https://www.forhers.com/blog/skin) [Drug Comparisons](https://www.forhers.com/drugs/compare) [Drugs & Medications](https://www.forhers.com/drugs/info) [Resource Hub](https://www.forhers.com/resources) ### Tools [BMI Calculator](https://www.forhers.com/tools/bmi-calculator) [TDEE Calculator](https://www.forhers.com/tools/tdee-calculator) [Calorie Deficit Calculator](https://www.forhers.com/tools/calorie-deficit-calculator) [Protein Calculator](https://www.forhers.com/tools/protein-calculator) [Quiz: Why Can't I Lose Weight?](https://www.forhers.com/tools/why-cant-i-lose-weight) [Daily Water Intake Calculator](https://www.forhers.com/tools/water-intake-calculator) ### Popular [Wegovy®](https://www.forhers.com/weight-loss/wegovy) [Birth Control](https://www.forhers.com/birth-control) [Latisse](https://www.forhers.com/hair-loss/latisse) [Propranolol](https://www.forhers.com/well-being/propranolol) [Oral Minoxidil](https://www.forhers.com/hair-loss/oral-minoxidil) [Minoxidil + Biotin Chew](https://www.forhers.com/hair-loss/minoxidil-biotin-chew) [Valacyclovir](https://www.forhers.com/drug/valacyclovir-herpes) [Bupropion](https://www.forhers.com/psychiatry/bupropion) [EscitalopramGeneric for Lexapro®](https://www.forhers.com/psychiatry/escitalopram) [Anti-Aging Rx Cream](https://www.forhers.com/skin-care/anti-aging) ### Hers [About Us](https://www.forhers.com/about) [Take Care(It's our blog)](https://www.forhers.com/blog) [How It Works](https://www.forhers.com/about/how-it-works) [Editorial Standards](https://www.forhers.com/editorial-standards) [FAQs](https://support.hims.com/hc/en-us) [Investors](https://investors.forhims.com/) ### Careers [Professionals](https://www.forhers.com/careers-professionals) [Providers](https://www.forhers.com/careers-providers) ### Connect [Customer Help Center](https://support.forhims.com/hc/en-us) [Press Center](https://news.hims.com/) [visit hims.com](https://www.hims.com/) [How To Get Antidepressants Written by Hadley Mendelsohn Published October 15, 2024](https://www.forhers.com/blog/how-to-get-antidepressants)
Readable Markdown
If you are dealing with depression, you should know you are not alone — far from it, in fact. The 2019 National Survey on Drug Use and Health [reported](https://www.nimh.nih.gov/health/statistics/major-depression.shtml) that more than 19 million adults in the U.S. experienced at least one major depressive episode during the previous year. In addition to [behavioral therapy for depression](https://www.forhers.com/blog/therapy-for-depression), one way to approach treatment for [depression](https://www.forhers.com/blog/dealing-with-depression) is through medication. A mental health professional can best help you figure out if you are depressed and will be able to guide you on treatment options — including possible medications. Until then, you may be curious about some of the best medications for depression — including moderate depression, major depression or clinical depression. Keep reading to learn about some of them. But, first, let us arm you with a bit more info about depression. A depressive disorder can be caused by a variety of factors. It’s often connected to low levels of certain neurotransmitters in your brain (like serotonin). Neuro-what? Neurotransmitters [relay](https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/neurotransmitters) information between your neurons. There are more than 100 different neurotransmitters, and a number of them are [essential](https://www.ncbi.nlm.nih.gov/books/NBK10795/) to how your brain and body function. There are a few different neurotransmitters that may be related to depression and its symptoms, [including:](https://www.health.harvard.edu/mind-and-mood/what-causes-depression) - **Serotonin,** which regulates things like your mood, hunger and sleep. Plus, it helps inhibit pain. There is research suggesting that some with depression have low levels of serotonin transmission in the brain. - **Norepinephrine**, which boosts your blood pressure and constricts blood vessels. But it may have an effect on mood, too — like influencing your level of motivation. It is thought that norepinephrine has a hand in depression. - **Dopamine**, a neurotransmitter you may have heard about. It has been connected to your perception of reality and also is involved in helping you feel motivated. Dopamine also plays a leading role in your brain’s reward system. - **Acetylcholine**, which [can help memory](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268065/) and is related to learning. It also aids in [focusing](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268065/) on tasks. - **Gamma-aminobutyric acid (GABA)**, which prevents certain types brain activity.[Research](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412149/) points to people with depression possibly having lower levels of GABA. [Antidepressant medication](https://www.forhers.com/blog/depression-medications) works by increasing levels of some neurotransmitters to help with symptoms of depression. Wondering what the symptoms of depression look like? Common side effects [include](https://www.nimh.nih.gov/health/publications/depression): - Constant feelings of sadness, anxiety or hopelessness - Feeling irritable, helpless or worthless - Low energy or tiredness - Changes in weight - Difficulty sleeping - Decreased appetite - Thoughts of self-harm or suicide If you notice that you have some of the symptoms listed above, you should seek help from a mental health professional. Whether you are dealing with mild or severe depression, a healthcare professional will be able to help identify the best course of treatment for you. Therapy and medication are both commonly used to treat depression — often in conjunction with one another, One thing to know about antidepressants: It can take [four to eight weeks](https://www.nimh.nih.gov/health/publications/depression/index.shtml) before you’ll see any improvement in your symptoms. There are many different types of medications that can [treat](https://screening.mhanational.org/content/what-meds-treat-depression/) depression. The four main types are selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors. A prescription drug called [bupropion](https://www.forhers.com/drugs/info/buproprion) (also sold as the brand name Wellbutrin®) is often prescribed for depression, and often also used to treat seasonal affective disorder and depressive episodes [associated](https://medlineplus.gov/druginfo/meds/a695033.html) with bipolar disorder. Bupropion is considered an atypical antidepressant — which just means it doesn’t fall under the four main classes of antidepressants. In addition to [buying bupropion online](https://www.forhers.com/psychiatry/bupropion), the other most common types of antidepressants prescribed for depression are SSRIs and SNRIs. ### **Selective Serotonin Reuptake Inhibitors** [Selective serotonin reuptake inhibitors (SSRIs)](https://www.forhers.com/blog/ssri-drugs-overview-types) are by far the most common type of antidepressant [prescribed](https://magazine.medlineplus.gov/article/commonly-prescribed-antidepressants-and-how-they-work) in the United States. This is partially because they do not have as many drug interactions or side effects as older antidepressants. SSRIs increase serotonin levels in your brain by [preventing your brain cells](https://www.ncbi.nlm.nih.gov/books/NBK554406/) from reabsorbing existing serotonin. Here are some common SSRIs prescribed for varying degrees of depression—including severe depression: - [Citalopram](https://www.forhers.com/psychiatry/citalopram). Also sold as the brand name Celexa®, this commonly prescribed oral antidepressant comes in tablet or liquid form. It’s also sometimes used to treat eating disorders, alcoholism and panic disorder. - Escitalopram. Also available under the brand name Lexapro®, this medication is [prescribed](https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021323s052,021365s037lbl.pdf) to treat depression and generalized anxiety disorder (GAD). - Fluoxetine. This popular medication (which is also sold under the brand name Prozac®) can be [used](https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/018936s109lbl.pdf) to treat depression along with conditions like obsessive-compulsive disorder (OCD), panic disorder, and bulimia nervosa. You can [buy fluoxetine online](https://www.forhers.com/psychiatry/fluoxetine) and other medications using Hers mental health services. - [Sertraline online](https://www.forhers.com/psychiatry/sertraline). Also sold under the brand name Zoloft®, this SSRI is commonly [prescribed](https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019839s091lbl.pdf) in the treatment of depression. Like fluoxetine, it is also used to treat OCD and panic disorder. You can [buy escitalopram online](https://www.forhers.com/psychiatry/escitalopram) and other medications using our online [mental health medication](https://www.forhers.com/blog/mental-health-medication) services. ### **Serotonin–Norepinephrine Reuptake Inhibitors** Serotonin–norepinephrine reuptake inhibitors (SNRIs) are another type of antidepressant. They are similar to SSRIs in that they prevent the reabsorption of serotonin, but they also block the reabsorption of [norepinephrine](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008300/) (another neurotransmitter), as well. Low levels of norepinephrine have been linked to [symptoms](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131098/) of depression — like difficulty concentrating and feeling sluggish. SNRIs that may be prescribed for depression include: - Desvenlafaxine, which is sold under the brand name Pristiq®. This SNRI is not only [used](https://medlineplus.gov/druginfo/meds/a608022.html#:~:text=Desvenlafaxine%20is%20used%20to%20treat,that%20help%20maintain%20mental%20balance.) in the treatment of depression, it is also prescribed off-label to treat certain symptoms such as hot flashes in menopausal women. - [Duloxetine](https://www.forhers.com/psychiatry/duloxetine), which is sold under the brand name Cymbalta®, is another SNRI [that may help](https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021427s053lbl.pdf) to treat depression along with generalized anxiety disorder. - Venlafaxine, which is sold under the brand name Effexor®. This [medication](https://medlineplus.gov/druginfo/meds/a694020.html) for depression also comes in an extended release form that may sometimes be prescribed to treat certain anxiety disorders. You can [buy venlafaxine online](https://www.forhers.com/psychiatry/venlafaxine) by using Hers online mental health service. There’s no magic equation when it comes to identifying the best antidepressant for you. You can [get depression medicine online](https://www.forhers.com/psychiatry) to get diagnosed and determine if medication will be the best course of treatment. From there, your healthcare provider will take into consideration your depression symptoms, other medical issues you may have and any other prescription drugs you are taking (as well as non-prescription meds). They may then prescribe you medication. You should feel free to ask any questions you may have — like about common side effects, if there is potential risk involved, alternative treatments for depression, and more. [Research](https://www.ncbi.nlm.nih.gov/books/NBK83442/) has shown that the different antidepressants work as well as one another. However, people react differently to the various medications. For this reason, you may have to try a few different medications before landing on one that works best for you. As previously mentioned, you should give the medication you're taking at least a month to see if it works. If it doesn’t, it’s important not to stop taking your medication suddenly, as that can cause withdrawal symptoms. Instead, speak to your healthcare provider to discuss the best approach for coming off one medication and trying another. You should also call your healthcare provider immediately if you notice any bothersome side effects from taking prescription antidepressants. There are a number of different medications used to treat depression. Two of the more common types are selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs). This is partially because they tend to have mild potential side effects. It takes an average of four to six weeks for antidepressants to start working, so you will need to be patient to see if a specific medication works for you. It’s also important to remember that you may need to try a few different options before settling on one that helps your depression. Untreated depression is no way to live. To figure out the best medication to treat your depression, you’ll need to work closely with a mental healthcare professional. ### Related Drug Comparisons | | | |---|---| | [Adderall vs. Lexapro](https://www.forhers.com/drugs/compare/adderall-vs-lexapro) | [Cymbalta vs. Prozac](https://www.forhers.com/drugs/compare/cymbalta-vs-prozac) | | [Buspirone vs. Xanax](https://www.forhers.com/drugs/compare/buspirone-vs-xanax) | [Cymbalta vs. Zoloft](https://www.forhers.com/drugs/compare/cymbalta-vs-zoloft) | | [Cymbalta vs. Lexapro](https://www.forhers.com/drugs/compare/cymbalta-vs-lexapro) | [Lexapro vs. Prozac](https://www.forhers.com/drugs/compare/lexapro-vs-prozac) | | [Lexapro vs. Wellbutrin](https://www.forhers.com/drugs/compare/lexapro-vs-wellbutrin) | [Lexapro vs. Zoloft](https://www.forhers.com/drugs/compare/lexapro-vs-zoloft) | | [Prozac vs. Zoloft](https://www.forhers.com/drugs/compare/prozac-vs-zoloft) | [Sertraline vs. Zoloft](https://www.forhers.com/drugs/compare/sertraline-vs-zoloft) | 23 Sources Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. 1. Major Depression. (2019, February). Retrieved from https://www.nimh.nih.gov/health/statistics/major-depression.shtml 2. Hyman, S.E. (2005, March 8). Neurotransmitters. Current Biology. 15 (5), PR154-R158. Retrieved from https://www.cell.com/current-biology/comments/S0960-9822(05)00208-3 3. Cooper, J.R., (2001). Neurotransmitters. International Encyclopedia of the Social and Behavioral Sciences. Retrieved from https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/neurotransmitters 4. What causes depression? (2019, June 24). Retrieved from https://www.health.harvard.edu/mind-and-mood/what-causes-depression 5. Higley, M.J. & Picciotto, M.R. (2014, December). Neuromodulation by Acetylcholine: Examples from Schizophrenia and Depression. Current Opinion in Neurobiology. 29, 88–95. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268065/ 6. Luscher, B., Shen, Q. & Sahir, N. (2011, April). The GABAergic Deficit Hypothesis of Major Depressive Disorder. Molecular Psychiatry. 16 (4), 383–406. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412149/ 7. Depression of Women: 5 Things to Know. National Institute of Mental Health. Retrieved from https://www.nimh.nih.gov/health/publications/depression-in-women 8. Depression. (2021). Retrieved from https://www.nimh.nih.gov/health/publications/depression/index.shtml 9. What Meds Treat Depression? Mental Health America. Retrieved from https://screening.mhanational.org/content/what-meds-treat-depression/ 10. Bupropion. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a695033.html 11. Atypical Antidepressants. Mental Health America. Retrieved from https://screening.mhanational.org/content/atypical-antidepressants/ 12. Commonly Prescribed Antidepressants and How They Work. Medline Plus. Retrieved from https://magazine.medlineplus.gov/article/commonly-prescribed-antidepressants-and-how-they-work 13. Chu, A., Wadhwa, R., (2021, May 10). Selective Serotonin Reuptake Inhibitors. Stat Pearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK554406/ 14. Citalopram. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a699001.html 15. Highlights of Prescribing Information, Lexapro. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda\_docs/label/2020/021323s052,021365s037lbl.pdf 16. Highlights of Prescribing Information, Prozac. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda\_docs/label/2020/018936s109lbl.pdf 17. Highlights of Prescribing Information, Zoloft. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda\_docs/label/2017/019839s091lbl.pdf 18. Sansone, R., Sansone, L., (2014). Serotonin Norepinephrine Reuptake Inhibitors: A Pharmacological Comparison. Innovations in Clinical Neuroscience. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008300/ 19. Morel, C., Briley, M., (2011). The importance of norepinephrine in depression. Neuropsychiatric Disease and Treatment. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131098/ 20. Desvenlafaxine. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a608022.html\#:~:text=Desvenlafaxine%20is%20used%20to%20treat,that%20help%20maintain%20mental%20balance. 21. Highlights of Prescribing Information, Cymbalta. FDA. Retrieved from https://www.accessdata.fda.gov/drugsatfda\_docs/label/2020/021427s053lbl.pdf 22. Venlafaxine. Medline Plus. Retrieved from https://medlineplus.gov/druginfo/meds/a694020.html 23. Gartlehner, G., Hansen, R., Morgan, L., et al. (2007). Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression. Agency for Healthcare Research and Quality. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK83442/
ML Classification
ML Categories
/Health
99.8%
/Health/Mental_Health
95.4%
/Health/Mental_Health/Depression
95.3%
Raw JSON
{
    "/Health": 998,
    "/Health/Mental_Health": 954,
    "/Health/Mental_Health/Depression": 953
}
ML Page Types
/Article
99.8%
/Article/Tutorial_or_Guide
51.3%
Raw JSON
{
    "/Article": 998,
    "/Article/Tutorial_or_Guide": 513
}
ML Intent Types
Informational
97.3%
Commercial
15.5%
Raw JSON
{
    "Informational": 973,
    "Commercial": 155
}
Content Metadata
Languageen
Authornull
Publish Timenot set
Original Publish Time2022-02-07 05:09:29 (4 years ago)
RepublishedNo
Word Count (Total)2,604
Word Count (Content)1,692
Links
External Links36
Internal Links76
Technical SEO
Meta NofollowNo
Meta NoarchiveNo
JS RenderedNo
Redirect Targetnull
Performance
Download Time (ms)2,777
TTFB (ms)2,002
Download Size (bytes)411,370
Shard79 (laksa)
Root Hash14475777380408463279
Unparsed URLcom,forhers!www,/blog/best-medication-for-depression s443