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| Meta Title | What Happens When We Lose Our Sense of Smell and Taste? | FoodUnfolded |
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| Boilerpipe Text | In the glowing frame of my phone's screen, I watch a teenager take a shot of Everclear, a U.S. brand of grain alcohol that goes as high as 95% alcohol by volume. She downs it, expressionless, looking into the camera and saying, âNope, nothing. I canât taste it.â At-home experiments like this have become a trend over the past 12 months, a lighthearted way for those experiencing one of the strange symptoms of COVID-19 to prove they have truly lost their sense of taste and smell.
COVID-19 & loss of smell
Losing oneâs sense of smell and taste is now widely recognized as one of the hallmarks of COVID-19
1
, the disease caused by a virus called SARS-CoV-2, but its diagnostic potential was initially brushed off by many experts.
2
âIt took roughly eight weeks from when we first understood this to get Public Health England to recognize loss of smell and taste as a symptom of COVID-19,â says Professor Barry Smith, founding director of the Centre for the Study of the Senses (CenSes).
3
 âBefore that, people reporting this sudden loss of smell were told by the helplines that it wasnât a symptom, so they were still turning up to workâeven in ICU departments.â
Smithâs Centre has brought the combined might of neuroscientists, clinical experts, and psychologists to this issue of anosmiaâthatâs the clinical term for loss of smell.
4
 He and his team successfully campaigned to have this symptom listed as one of the tell-tale signs of COVID-19 infection and have been part of the research effort to understand how the virus produces these symptoms.Â
What happens inside our nose when we lose our sense of smell?
A patch of cells called olfactory sensory neurons sits at the very top of your nasal cavity. The âheadsâ of these neurons are embedded in that patch of tissue in your nose, while their long âtailsâ connect directly to the part of your brain that processes smells. Their heads even have little sticky feelers, called cilia, that poke out from the tissue to bind the tiny odour molecules wafting in through our nostrils. But itâs not just the neurons themselves up there in your noseâtheyâre supported by other non-sensory cells that act as structure, a sort of scaffolding. And when it comes to virally-induced anosmia, these are the issue.
5
The structural cells not only keep everything in place but also keep those ciliaâthe little scent-catching tendrilsâin working order. While the neurons donât have the receptor that SARS-CoV-2 uses to get inside our cells, the structural cells do. And, of course, one of the primary infection sites of a respiratory virus like SARS-CoV-2 is inside your nose.
6
So when the virus gets inside those structural cells, it can damage or destroy them.Â
âIt may be that you can't get odour molecules into the receptors,â explains Smith. The damaged structural cells can no longer do their job of helping odour molecules attach to your olfactory neurons. âAlso, there are a lot of inflammatory responses that the body mounts to the infection of these cells and inflammation may be responsible for preventing odour molecules from accessing the olfactory receptors.â
7
This is quite a different anosmia from the blocked nose you may get from a common cold or allergiesâthatâs just mucus and inflammation blocking the odour molecules from accessing that patch of olfactory tissue in the first place.
8
But itâs not just SARS-CoV-2 that can impact these olfactory neuronsâ ability to send signals to the brain. Other cold and flu viruses can do this too, but until now we haven't known much about how common it is. The pandemic has meant that enough people have experienced virally-induced anosmiaâand all at the same timeâfor the world to pay a little more attention.
9
What about taste?Â
It turns out that much of our perception of taste comes from the way something smells. Our tongueâs receptors are relatively rudimentary, capable of detecting the presence of compounds that register as sweet, sour, bitter, or salty. We donât just receive scent input when inhalingâodour molecules also travel from our mouths up to that patch of olfactory neurons while weâre tasting, chewing, and swallowing.
10
  And as far as we know, COVID-19 does not seem to be affecting our taste buds.
Smith conducted an informal experiment to investigate this. He asked people reporting COVID-19-related anosmia and loss of taste to put a drop of lemon juice on their tongue. âThey would say, âOh yeah, I can taste that sour taste, but that's all.â And then they would realize how much of what they were calling âtastingâ was actually due to smell.âÂ
When I ask Smith about the experiments with strong alcohol Iâve witnessed on social media, he points out that thereâs actually a third factor at play.Â
âThat's the contribution of the trigeminal nerve. The trigeminal nerve serves the eyes, the nose and the mouth. It's what rings bells when you have too much wasabi and it tingles and hurts, that's the irritation of your nerve endings.â
Those who canât feel those sensations may report this as a loss of âtasteâ, but it may actually be viral damage to the trigeminal nerveâs ability to receive and send signals, much like whatâs happening to the olfactory neuronsâerasing your ability to perceive the bracing burn of a shot of spirits.Â
That nerve creates sensations like the tingles from mustard, the cooling effect of mint, and some of the fiery feeling from spicy chilis. Itâs separate from the input coming into the brain from the olfactory sensory neurons at the top of your nose, but the trigeminal nerve, the olfactory neurons and the taste buds are all separate systems that come together to create what we generally refer to as âflavourâ.
11
How long does it take to recover our senses? Â
Losing any of this input can be very distressing. We donât notice it consciously, but our sense of smell is constantly providing us with input about our surroundings. Itâs a fundamental part of how we connect to our homes, our partners, and our children. Itâs how we tell if food has gone off or is safe to eat or how we know if something is burning in another room. Those who experience long-term anosmia report depression, anxiety, and a sense of dissociation from the individuals around themâitâs as if everything is muted, and they canât experience their lives as fully.
12
âWhen you no longer have a sense of smell, you can no longer access âcomfort food.â In the beginning, there can be a tendency to gain weight because you keep eating to try and find that satisfaction that never comes. You never quite hit the pleasure button.â
Chrissi Kelly, Founder of
AbScent.org
But thereâs hope. Olfactory neurons do regenerate (as do the structural cells around them), and most people who experience virally induced anosmia recover, even if it takes some longer than others. Some individuals may also pass through a phase called parosmia, where a sense of smell begins to return, but things donât smell the same. CenSus and other research groups are looking into the trends popping up in those reporting parosmia, such as: why do so many report that the smell of coffee, once a tempting incitement to leave bed, now registers instead as the smell of rancid bin juice?
13
âParosmia is completely different to anosmia â they arenât on a sliding continuum of how much you can smell. If you think of it as a radio, anosmia would be having the volume completely off and parosmia would be having the volume on, but only hearing the white noise between radio stations.â
Chrissi Kelly, Founder of
AbScent.org
âWork outâ with your nose
Whether youâre recovering from a virus or not, being more aware of your sense of smell is surprisingly beneficial. âSmell is one of those âuse it or lose itâ senses where, if we are actively paying attentionâsmelling the smell of the woods and the grass, the smell of the city, smelling our foodâthat actually keeps the olfactory brain going longer,â says Smith.
14
He references a study that demonstrated improved cognitive function in older populations participating in daily smell training.
15
This is an activity thatâs designed to help with recovery from anosmia, virally induced or not. But Smith says we can all be doing smell training to protect our sense of smell, especially as we age, or we can simply be proactive about consciously noticing smells throughout our day.
16
 This is not a sentence I ever thought Iâd write in the context of a science piece, but I guess itâs time to break out the essential oils.Â
How you can still appreciate your foodÂ
If you or a loved one is experiencing anosmia, itâs important to be mindful about connecting with your social support network in deliberate ways to keep from feeling isolated. If youâre struggling to enjoy your food without flavourful sensory input, try Smithâs experiment for yourself. What can you still tasteâlemon juice? Sour candy? Spicy food? See if you can have fun with it while you train your way back to full smelling power.Â
âTo help people with anosmia to make their food as pleasurable as possible, we encourage them to maximise contrasts in taste, texture, colours and even temperatures: for instance, sweet/sour, hot/cold, crisp/soft, etc. So perhaps something like creamy goatâs cheese on a bed of crispy greens with sweet pomegranate seeds.â
Chrissi Kelly, Founder of
AbScent.org
If you pass through that strange parosmia phase, Smith says many who experience it find that foods containing sulfur compounds are particularly off-putting. Avoid foods like eggs, meat and fish, nuts, legumes, etc.
âWhen parosmia hits you badly, your sense of smell is so distorted that you can barely eat at all. Many important food categories smell like sewage or spoiling meat, including fried meat, roasted and toasted foods, anything with onions, garlic or eggs.âÂ
Chrissi Kelly, Founder of
AbScent.org
It may sound daunting to work around limitations like this, but it could be an opportunity to experiment and get creative with ingredients you still find palatable. And if very few tastes are palatable, try getting creative with textures and temperatures, as well as visual presentation, to make mealtimes as enjoyable as possible even while grappling with this difficult condition.Â
Â
*Author's note:
If youâre unsure if youâre experiencing COVID-19-induced anosmia, itâs important to self-isolate as soon as you can and contact your healthcare provider for next steps.Â
Here are Smithâs tips for assessing if what youâre experiencing is connected to COVID-19:
âCan you breathe freely, but odours are not there? And did it happen suddenlyâthe sudden onset seems to be very marked. It's not a sort of gradual turning down of the intensity. It's gone from one day to the next.â |
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# What Happens When We Lose Our Sense of Smell and Taste?
How COVID-19 impacts our senses
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**Published** on 12.05.2021
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In the glowing frame of my phone's screen, I watch a teenager take a shot of Everclear, a U.S. brand of grain alcohol that goes as high as 95% alcohol by volume. She downs it, expressionless, looking into the camera and saying, âNope, nothing. I canât taste it.â At-home experiments like this have become a trend over the past 12 months, a lighthearted way for those experiencing one of the strange symptoms of COVID-19 to prove they have truly lost their sense of taste and smell.

## COVID-19 & loss of smell
Losing oneâs sense of smell and taste is now widely recognized as one of the hallmarks of COVID-19[1](https://www.bmj.com/content/370/bmj.m2808), the disease caused by a virus called SARS-CoV-2, but its diagnostic potential was initially brushed off by many experts.[2](https://pn.bmj.com/content/20/4/343)
âIt took roughly eight weeks from when we first understood this to get Public Health England to recognize loss of smell and taste as a symptom of COVID-19,â says Professor Barry Smith, founding director of the Centre for the Study of the Senses (CenSes).[3](https://philosophy.sas.ac.uk/centres/censes) âBefore that, people reporting this sudden loss of smell were told by the helplines that it wasnât a symptom, so they were still turning up to workâeven in ICU departments.â
Smithâs Centre has brought the combined might of neuroscientists, clinical experts, and psychologists to this issue of anosmiaâthatâs the clinical term for loss of smell.[4](https://www.nhs.uk/conditions/lost-or-changed-sense-smell/) He and his team successfully campaigned to have this symptom listed as one of the tell-tale signs of COVID-19 infection and have been part of the research effort to understand how the virus produces these symptoms.
## What happens inside our nose when we lose our sense of smell?

A patch of cells called olfactory sensory neurons sits at the very top of your nasal cavity. The âheadsâ of these neurons are embedded in that patch of tissue in your nose, while their long âtailsâ connect directly to the part of your brain that processes smells. Their heads even have little sticky feelers, called cilia, that poke out from the tissue to bind the tiny odour molecules wafting in through our nostrils. But itâs not just the neurons themselves up there in your noseâtheyâre supported by other non-sensory cells that act as structure, a sort of scaffolding. And when it comes to virally-induced anosmia, these are the issue.[5](https://doi.org/10.1177/1073858420956905)
The structural cells not only keep everything in place but also keep those ciliaâthe little scent-catching tendrilsâin working order. While the neurons donât have the receptor that SARS-CoV-2 uses to get inside our cells, the structural cells do. And, of course, one of the primary infection sites of a respiratory virus like SARS-CoV-2 is inside your nose.[6](https://www.foodunfolded.com/article/anosmia#ref6) So when the virus gets inside those structural cells, it can damage or destroy them.
âIt may be that you can't get odour molecules into the receptors,â explains Smith. The damaged structural cells can no longer do their job of helping odour molecules attach to your olfactory neurons. âAlso, there are a lot of inflammatory responses that the body mounts to the infection of these cells and inflammation may be responsible for preventing odour molecules from accessing the olfactory receptors.â[7](https://www.sciencedirect.com/science/article/pii/S0304394021000720?casa_token=MKF9JXH2c58AAAAA:Zu5ApyD-NVZd_SKmmU2oba9xJqbOW4HJjWqYvCCswKIgN496ncCSnUtWX2vHyy8CPIWBzS-vhVM)
This is quite a different anosmia from the blocked nose you may get from a common cold or allergiesâthatâs just mucus and inflammation blocking the odour molecules from accessing that patch of olfactory tissue in the first place.[8](https://connect.uclahealth.org/2020/09/21/covid-19-affects-sense-of-smell-differently-than-colds-flu/) But itâs not just SARS-CoV-2 that can impact these olfactory neuronsâ ability to send signals to the brain. Other cold and flu viruses can do this too, but until now we haven't known much about how common it is. The pandemic has meant that enough people have experienced virally-induced anosmiaâand all at the same timeâfor the world to pay a little more attention.[9](https://doi.org/10.1002/alr.22624)
## What about taste?
It turns out that much of our perception of taste comes from the way something smells. Our tongueâs receptors are relatively rudimentary, capable of detecting the presence of compounds that register as sweet, sour, bitter, or salty. We donât just receive scent input when inhalingâodour molecules also travel from our mouths up to that patch of olfactory neurons while weâre tasting, chewing, and swallowing.[10](https://www.ncbi.nlm.nih.gov/books/NBK279408/) And as far as we know, COVID-19 does not seem to be affecting our taste buds.
Smith conducted an informal experiment to investigate this. He asked people reporting COVID-19-related anosmia and loss of taste to put a drop of lemon juice on their tongue. âThey would say, âOh yeah, I can taste that sour taste, but that's all.â And then they would realize how much of what they were calling âtastingâ was actually due to smell.â
When I ask Smith about the experiments with strong alcohol Iâve witnessed on social media, he points out that thereâs actually a third factor at play.
âThat's the contribution of the trigeminal nerve. The trigeminal nerve serves the eyes, the nose and the mouth. It's what rings bells when you have too much wasabi and it tingles and hurts, that's the irritation of your nerve endings.â

Those who canât feel those sensations may report this as a loss of âtasteâ, but it may actually be viral damage to the trigeminal nerveâs ability to receive and send signals, much like whatâs happening to the olfactory neuronsâerasing your ability to perceive the bracing burn of a shot of spirits.
That nerve creates sensations like the tingles from mustard, the cooling effect of mint, and some of the fiery feeling from spicy chilis. Itâs separate from the input coming into the brain from the olfactory sensory neurons at the top of your nose, but the trigeminal nerve, the olfactory neurons and the taste buds are all separate systems that come together to create what we generally refer to as âflavourâ.[11](https://pubmed.ncbi.nlm.nih.gov/20386632/)
## How long does it take to recover our senses?
Losing any of this input can be very distressing. We donât notice it consciously, but our sense of smell is constantly providing us with input about our surroundings. Itâs a fundamental part of how we connect to our homes, our partners, and our children. Itâs how we tell if food has gone off or is safe to eat or how we know if something is burning in another room. Those who experience long-term anosmia report depression, anxiety, and a sense of dissociation from the individuals around themâitâs as if everything is muted, and they canât experience their lives as fully. [12](https://www.fifthsense.org.uk/psychology-and-smell/#:~:text=The%20Psychological%20Impact%20of%20Smell%20Loss&text=Anosmia%20sufferers%20often%20talk%20of,and%20can%20lead%20to%20depression)
*âWhen you no longer have a sense of smell, you can no longer access âcomfort food.â In the beginning, there can be a tendency to gain weight because you keep eating to try and find that satisfaction that never comes. You never quite hit the pleasure button.â*
Chrissi Kelly, Founder of [AbScent.org](https://abscent.org/)
But thereâs hope. Olfactory neurons do regenerate (as do the structural cells around them), and most people who experience virally induced anosmia recover, even if it takes some longer than others. Some individuals may also pass through a phase called parosmia, where a sense of smell begins to return, but things donât smell the same. CenSus and other research groups are looking into the trends popping up in those reporting parosmia, such as: why do so many report that the smell of coffee, once a tempting incitement to leave bed, now registers instead as the smell of rancid bin juice?[13](https://doi.org/10.1136/bmj.m4332)

*âParosmia is completely different to anosmia â they arenât on a sliding continuum of how much you can smell. If you think of it as a radio, anosmia would be having the volume completely off and parosmia would be having the volume on, but only hearing the white noise between radio stations.â*
Chrissi Kelly, Founder of [AbScent.org](https://abscent.org/)
## âWork outâ with your nose
Whether youâre recovering from a virus or not, being more aware of your sense of smell is surprisingly beneficial. âSmell is one of those âuse it or lose itâ senses where, if we are actively paying attentionâsmelling the smell of the woods and the grass, the smell of the city, smelling our foodâthat actually keeps the olfactory brain going longer,â says Smith.[14](https://doi.org/10.1093/chemse/bjaa049)
He references a study that demonstrated improved cognitive function in older populations participating in daily smell training.[15](https://abscent.org/learn-us/smell-training) This is an activity thatâs designed to help with recovery from anosmia, virally induced or not. But Smith says we can all be doing smell training to protect our sense of smell, especially as we age, or we can simply be proactive about consciously noticing smells throughout our day.[16](https://pubmed.ncbi.nlm.nih.gov/28429377/) This is not a sentence I ever thought Iâd write in the context of a science piece, but I guess itâs time to break out the essential oils.
## How you can still appreciate your food
If you or a loved one is experiencing anosmia, itâs important to be mindful about connecting with your social support network in deliberate ways to keep from feeling isolated. If youâre struggling to enjoy your food without flavourful sensory input, try Smithâs experiment for yourself. What can you still tasteâlemon juice? Sour candy? Spicy food? See if you can have fun with it while you train your way back to full smelling power.

*âTo help people with anosmia to make their food as pleasurable as possible, we encourage them to maximise contrasts in taste, texture, colours and even temperatures: for instance, sweet/sour, hot/cold, crisp/soft, etc. So perhaps something like creamy goatâs cheese on a bed of crispy greens with sweet pomegranate seeds.â*
Chrissi Kelly, Founder of [AbScent.org](https://abscent.org/)
If you pass through that strange parosmia phase, Smith says many who experience it find that foods containing sulfur compounds are particularly off-putting. Avoid foods like eggs, meat and fish, nuts, legumes, etc.
*âWhen parosmia hits you badly, your sense of smell is so distorted that you can barely eat at all. Many important food categories smell like sewage or spoiling meat, including fried meat, roasted and toasted foods, anything with onions, garlic or eggs.â*
Chrissi Kelly, Founder of [AbScent.org](https://abscent.org/)
It may sound daunting to work around limitations like this, but it could be an opportunity to experiment and get creative with ingredients you still find palatable. And if very few tastes are palatable, try getting creative with textures and temperatures, as well as visual presentation, to make mealtimes as enjoyable as possible even while grappling with this difficult condition.
\*Author's note:
If youâre unsure if youâre experiencing COVID-19-induced anosmia, itâs important to self-isolate as soon as you can and contact your healthcare provider for next steps.
Here are Smithâs tips for assessing if what youâre experiencing is connected to COVID-19:
*âCan you breathe freely, but odours are not there? And did it happen suddenlyâthe sudden onset seems to be very marked. It's not a sort of gradual turning down of the intensity. It's gone from one day to the next.â*
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## References
1. [Walker, A., Pottinger, G., Scott, A., Hopkins, C. (2020). âAnosmia and loss of smell in the era of Covid-19.â British Medical Journal. Accessed 08 March 2021.](https://www.bmj.com/content/370/bmj.m2808%20)
2. [Mermelstein, S. (2020). âAcute anosmia from COVID-19 infectionâ. Practical Neurology. Accessed 09 March 2021](https://pn.bmj.com/content/20/4/343%20)
3. [CenSes, The Centre for the Study of the Senses. Accessed 08 March 2021.](https://philosophy.sas.ac.uk/centres/censes%20)
1. [NHS, Lost or changed sense of smell. Accessed 08 March 2021.](https://www.nhs.uk/conditions/lost-or-changed-sense-smell/%20)
2. [Butowt, R., & von Bartheld, C. S. (2020). âAnosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infectionâ. The Neuroscientist. Accessed 08 March 2021.](https://doi.org/10.1177/1073858420956905%20)
3. [Meng, X., Deng, Y., Dai, Z., & Meng, Z. (2020). âCOVID-19 and anosmia: A review based on up-to-date knowledgeâ. American Journal of Otolaryngology. Accessed March 08 2021.](https://doi.org/10.1016/j.amjoto.2020.102581%20)
4. [Mastrangelo, A., Bonato, M., Cinque, P. (2021). âSmell and taste disorders in COVID-19: From pathogenesis to clinical features and outcomes.â Neuroscience Letters. Accessed May 05 2021.](https://www.sciencedirect.com/science/article/pii/S0304394021000720?casa_token=MKF9JXH2c58AAAAA:Zu5ApyD-NVZd_SKmmU2oba9xJqbOW4HJjWqYvCCswKIgN496ncCSnUtWX2vHyy8CPIWBzS-vhVM)
5. [Glazier, E., & Ko, E. (2020). âCOVID-19 affects sense of smell differently than colds, fluâ. UCLA Health. Accessed 09 March 2021.](https://connect.uclahealth.org/2020/09/21/covid-19-affects-sense-of-smell-differently-than-colds-flu/%20)
6. [Hura, N., Xie, D. X., Choby, et al. (2020). âTreatment of post-viral olfactory dysfunction: an evidence-based review with recommendationsâ. International Forum of Allergy & Rhinology. Accessed 08 March 2021.](https://doi.org/10.1002/alr.22624%20)
7. [InformedHealth.org (2016). âHow does our sense of taste work?â. Institute for Quality and Efficiency in Health Care. Accessed 10 March 2021.](https://www.ncbi.nlm.nih.gov/books/NBK279408/%20)
8. [Sanders R. D. (2010). âThe Trigeminal (V) and Facial (VII) Cranial Nerves: Head and Face Sensation and Movementâ. Psychiatry. Accessed 08 March 2021.](https://pubmed.ncbi.nlm.nih.gov/20386632/%20)
9. [Psychology and Smell (2020). The Fifth Sense. Accessed 08 March 2021.](https://www.fifthsense.org.uk/psychology-and-smell/#:~:text=The%20Psychological%20Impact%20of%20Smell%20Loss&text=Anosmia%20sufferers%20often%20talk%20of,and%20can%20lead%20to%20depression)
10. [Rimmer, A. (2020) âSixty seconds on...parosmiaâ British Medical Journal. Accessed 08 March 2021.](https://doi.org/10.1136/bmj.m4332%20)
11. [Olofsson, J.K., Ekström, I., Lindström, J., et al. (2020) âSmell-Based Memory Training: Evidence of Olfactory Learning and Transfer to the Visual Domainâ. Chemical Senses. Accessed 09 March 2021.](https://doi.org/10.1093/chemse/bjaa049%20)
12. [âWelcome to smell trainingâ. (2021) Abscent. Accessed 07 March 2021.](https://abscent.org/learn-us/smell-training%20)
13. [Birte-Antina, W., Ilona, C., Antje, H., Thomas, H. (2018). âOlfactory training with older peopleâ. International Journal of Geriatric Psychiatry. Accessed March 08 2021.](https://pubmed.ncbi.nlm.nih.gov/28429377/%20)
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| Readable Markdown | In the glowing frame of my phone's screen, I watch a teenager take a shot of Everclear, a U.S. brand of grain alcohol that goes as high as 95% alcohol by volume. She downs it, expressionless, looking into the camera and saying, âNope, nothing. I canât taste it.â At-home experiments like this have become a trend over the past 12 months, a lighthearted way for those experiencing one of the strange symptoms of COVID-19 to prove they have truly lost their sense of taste and smell.

## COVID-19 & loss of smell
Losing oneâs sense of smell and taste is now widely recognized as one of the hallmarks of COVID-19[1](https://www.bmj.com/content/370/bmj.m2808), the disease caused by a virus called SARS-CoV-2, but its diagnostic potential was initially brushed off by many experts.[2](https://pn.bmj.com/content/20/4/343)
âIt took roughly eight weeks from when we first understood this to get Public Health England to recognize loss of smell and taste as a symptom of COVID-19,â says Professor Barry Smith, founding director of the Centre for the Study of the Senses (CenSes).[3](https://philosophy.sas.ac.uk/centres/censes) âBefore that, people reporting this sudden loss of smell were told by the helplines that it wasnât a symptom, so they were still turning up to workâeven in ICU departments.â
Smithâs Centre has brought the combined might of neuroscientists, clinical experts, and psychologists to this issue of anosmiaâthatâs the clinical term for loss of smell.[4](https://www.nhs.uk/conditions/lost-or-changed-sense-smell/) He and his team successfully campaigned to have this symptom listed as one of the tell-tale signs of COVID-19 infection and have been part of the research effort to understand how the virus produces these symptoms.
## What happens inside our nose when we lose our sense of smell?

A patch of cells called olfactory sensory neurons sits at the very top of your nasal cavity. The âheadsâ of these neurons are embedded in that patch of tissue in your nose, while their long âtailsâ connect directly to the part of your brain that processes smells. Their heads even have little sticky feelers, called cilia, that poke out from the tissue to bind the tiny odour molecules wafting in through our nostrils. But itâs not just the neurons themselves up there in your noseâtheyâre supported by other non-sensory cells that act as structure, a sort of scaffolding. And when it comes to virally-induced anosmia, these are the issue.[5](https://doi.org/10.1177/1073858420956905)
The structural cells not only keep everything in place but also keep those ciliaâthe little scent-catching tendrilsâin working order. While the neurons donât have the receptor that SARS-CoV-2 uses to get inside our cells, the structural cells do. And, of course, one of the primary infection sites of a respiratory virus like SARS-CoV-2 is inside your nose.[6](https://www.foodunfolded.com/article/anosmia#ref6) So when the virus gets inside those structural cells, it can damage or destroy them.
âIt may be that you can't get odour molecules into the receptors,â explains Smith. The damaged structural cells can no longer do their job of helping odour molecules attach to your olfactory neurons. âAlso, there are a lot of inflammatory responses that the body mounts to the infection of these cells and inflammation may be responsible for preventing odour molecules from accessing the olfactory receptors.â[7](https://www.sciencedirect.com/science/article/pii/S0304394021000720?casa_token=MKF9JXH2c58AAAAA:Zu5ApyD-NVZd_SKmmU2oba9xJqbOW4HJjWqYvCCswKIgN496ncCSnUtWX2vHyy8CPIWBzS-vhVM)
This is quite a different anosmia from the blocked nose you may get from a common cold or allergiesâthatâs just mucus and inflammation blocking the odour molecules from accessing that patch of olfactory tissue in the first place.[8](https://connect.uclahealth.org/2020/09/21/covid-19-affects-sense-of-smell-differently-than-colds-flu/) But itâs not just SARS-CoV-2 that can impact these olfactory neuronsâ ability to send signals to the brain. Other cold and flu viruses can do this too, but until now we haven't known much about how common it is. The pandemic has meant that enough people have experienced virally-induced anosmiaâand all at the same timeâfor the world to pay a little more attention.[9](https://doi.org/10.1002/alr.22624)
## What about taste?
It turns out that much of our perception of taste comes from the way something smells. Our tongueâs receptors are relatively rudimentary, capable of detecting the presence of compounds that register as sweet, sour, bitter, or salty. We donât just receive scent input when inhalingâodour molecules also travel from our mouths up to that patch of olfactory neurons while weâre tasting, chewing, and swallowing.[10](https://www.ncbi.nlm.nih.gov/books/NBK279408/) And as far as we know, COVID-19 does not seem to be affecting our taste buds.
Smith conducted an informal experiment to investigate this. He asked people reporting COVID-19-related anosmia and loss of taste to put a drop of lemon juice on their tongue. âThey would say, âOh yeah, I can taste that sour taste, but that's all.â And then they would realize how much of what they were calling âtastingâ was actually due to smell.â
When I ask Smith about the experiments with strong alcohol Iâve witnessed on social media, he points out that thereâs actually a third factor at play.
âThat's the contribution of the trigeminal nerve. The trigeminal nerve serves the eyes, the nose and the mouth. It's what rings bells when you have too much wasabi and it tingles and hurts, that's the irritation of your nerve endings.â

Those who canât feel those sensations may report this as a loss of âtasteâ, but it may actually be viral damage to the trigeminal nerveâs ability to receive and send signals, much like whatâs happening to the olfactory neuronsâerasing your ability to perceive the bracing burn of a shot of spirits.
That nerve creates sensations like the tingles from mustard, the cooling effect of mint, and some of the fiery feeling from spicy chilis. Itâs separate from the input coming into the brain from the olfactory sensory neurons at the top of your nose, but the trigeminal nerve, the olfactory neurons and the taste buds are all separate systems that come together to create what we generally refer to as âflavourâ.[11](https://pubmed.ncbi.nlm.nih.gov/20386632/)
## How long does it take to recover our senses?
Losing any of this input can be very distressing. We donât notice it consciously, but our sense of smell is constantly providing us with input about our surroundings. Itâs a fundamental part of how we connect to our homes, our partners, and our children. Itâs how we tell if food has gone off or is safe to eat or how we know if something is burning in another room. Those who experience long-term anosmia report depression, anxiety, and a sense of dissociation from the individuals around themâitâs as if everything is muted, and they canât experience their lives as fully. [12](https://www.fifthsense.org.uk/psychology-and-smell/#:~:text=The%20Psychological%20Impact%20of%20Smell%20Loss&text=Anosmia%20sufferers%20often%20talk%20of,and%20can%20lead%20to%20depression)
*âWhen you no longer have a sense of smell, you can no longer access âcomfort food.â In the beginning, there can be a tendency to gain weight because you keep eating to try and find that satisfaction that never comes. You never quite hit the pleasure button.â*
Chrissi Kelly, Founder of [AbScent.org](https://abscent.org/)
But thereâs hope. Olfactory neurons do regenerate (as do the structural cells around them), and most people who experience virally induced anosmia recover, even if it takes some longer than others. Some individuals may also pass through a phase called parosmia, where a sense of smell begins to return, but things donât smell the same. CenSus and other research groups are looking into the trends popping up in those reporting parosmia, such as: why do so many report that the smell of coffee, once a tempting incitement to leave bed, now registers instead as the smell of rancid bin juice?[13](https://doi.org/10.1136/bmj.m4332)

*âParosmia is completely different to anosmia â they arenât on a sliding continuum of how much you can smell. If you think of it as a radio, anosmia would be having the volume completely off and parosmia would be having the volume on, but only hearing the white noise between radio stations.â*
Chrissi Kelly, Founder of [AbScent.org](https://abscent.org/)
## âWork outâ with your nose
Whether youâre recovering from a virus or not, being more aware of your sense of smell is surprisingly beneficial. âSmell is one of those âuse it or lose itâ senses where, if we are actively paying attentionâsmelling the smell of the woods and the grass, the smell of the city, smelling our foodâthat actually keeps the olfactory brain going longer,â says Smith.[14](https://doi.org/10.1093/chemse/bjaa049)
He references a study that demonstrated improved cognitive function in older populations participating in daily smell training.[15](https://abscent.org/learn-us/smell-training) This is an activity thatâs designed to help with recovery from anosmia, virally induced or not. But Smith says we can all be doing smell training to protect our sense of smell, especially as we age, or we can simply be proactive about consciously noticing smells throughout our day.[16](https://pubmed.ncbi.nlm.nih.gov/28429377/) This is not a sentence I ever thought Iâd write in the context of a science piece, but I guess itâs time to break out the essential oils.
## How you can still appreciate your food
If you or a loved one is experiencing anosmia, itâs important to be mindful about connecting with your social support network in deliberate ways to keep from feeling isolated. If youâre struggling to enjoy your food without flavourful sensory input, try Smithâs experiment for yourself. What can you still tasteâlemon juice? Sour candy? Spicy food? See if you can have fun with it while you train your way back to full smelling power.

*âTo help people with anosmia to make their food as pleasurable as possible, we encourage them to maximise contrasts in taste, texture, colours and even temperatures: for instance, sweet/sour, hot/cold, crisp/soft, etc. So perhaps something like creamy goatâs cheese on a bed of crispy greens with sweet pomegranate seeds.â*
Chrissi Kelly, Founder of [AbScent.org](https://abscent.org/)
If you pass through that strange parosmia phase, Smith says many who experience it find that foods containing sulfur compounds are particularly off-putting. Avoid foods like eggs, meat and fish, nuts, legumes, etc.
*âWhen parosmia hits you badly, your sense of smell is so distorted that you can barely eat at all. Many important food categories smell like sewage or spoiling meat, including fried meat, roasted and toasted foods, anything with onions, garlic or eggs.â*
Chrissi Kelly, Founder of [AbScent.org](https://abscent.org/)
It may sound daunting to work around limitations like this, but it could be an opportunity to experiment and get creative with ingredients you still find palatable. And if very few tastes are palatable, try getting creative with textures and temperatures, as well as visual presentation, to make mealtimes as enjoyable as possible even while grappling with this difficult condition.
\*Author's note:
If youâre unsure if youâre experiencing COVID-19-induced anosmia, itâs important to self-isolate as soon as you can and contact your healthcare provider for next steps.
Here are Smithâs tips for assessing if what youâre experiencing is connected to COVID-19:
*âCan you breathe freely, but odours are not there? And did it happen suddenlyâthe sudden onset seems to be very marked. It's not a sort of gradual turning down of the intensity. It's gone from one day to the next.â* |
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