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Discover what is Stannous Fluoride Toothpaste and its importance to prevent cavities and other oral health problems. [Read More](https://www.colgate.com/en-us/oral-health/fluoride/what-is-stannous-fluoride-toothpaste)  TEETH WHITENING Whitening toothpaste - hydrogen peroxide vs. carbamide peroxide If you lose one or more of your front teeth due to injury or decay, you may feel ... 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[Oral Health and Dental Care \| Colgate®](https://www.colgate.com/en-us) 2. [Mission](https://www.colgate.com/en-us/mission) 3. Science and Innovation  # Changing the world, one breakthrough at a time # Changing the world, one breakthrough at a time With over 200 years of experience, we are the most trusted oral care products company across the globe. We’ve earned that trust because we invest more in research and development than any other oral healthcare company. Our experts use cutting-edge technology to create the scientific-led products you need for your best, healthiest smile. Our Colgate technology campus Our team of over 900, who work at our state-of-the-art research and development facility in New Jersey, conducts over 200 clinical trials and files around 100 patents each year. Using science to innovate lets us understand the true health benefits of our products and it helps us to develop new products to address emerging conditions. Watch the video to learn more about the Volpe Clinical Research Center.  ## Emerging ingredient innovation through clinical studies Our oral health clinical investigations have studied the benefit of products designed to improve teeth whitening, gingival health, tooth sensitivity, and plaque removal. The studies also help us to understand the biological processes that lead to oral disease so that we can create better therapies to prevent and treat them. As a result, we can develop groundbreaking products using advanced scientific technologies which deliver remarkable results. [See Our Ingredients](https://www.colgate.com/en-us/mission/science-and-innovation/ingredients)   ## Pushing the limits of research and development into space Driven by innovation, we partnered with the International Space Station (ISS), under the sponsorship of the ISS U.S. National Laboratory to conduct the first-ever oral care experiment in space. As we are constantly looking for new ways to create more effective therapies, we developed an experiment to study how plaque grows in microgravity. The results of testing in space could benefit more than half of the world’s population in the next five to ten years. This is the first of several research projects that we have planned in partnership with the ISS National Lab. Recently, we signed a Space Act Agreement with NASA to continue to explore solutions to the health and sustainability challenges we have here on Earth. [Read The Story](https://www.colgatepalmolive.com/en-us/who-we-are/stories/nasa-space-act-agreement)    ## Meet our team of oral health care experts Taking the best care of your oral health, not to mention the planet, means we rely on the expertise and future-focused thinking of some of the best scientific minds in the business. [Meet Our Experts](https://www.colgate.com/en-us/mission/science-and-innovation/dental-experts)  ## Partnering with dental professionals Your dentist is your best source of information and oral health care. We are proud to have the largest network of partnerships with Dental Professionals and Public Health Organizations.  Groundbreaking science creates groundbreaking products Our scientific research and development has led to more patented innovations than any other oral care company. Here are some of the latest: Optic White® LED Whitening Device and Pen Fueled by purple wavelength technology, the lightweight, flexible LED device amplifies the enamel-safe hydrogen peroxide serum for exceptional, quicker and less peroxide-dependent whitening results. The Pen allows you to apply the enamel-safe serum that removes stains. [Learn More About Whitening](https://www.colgate.com/en-us/optic-white) Optic White® LED Whitening Device and Pen Fueled by purple wavelength technology, the lightweight, flexible LED device amplifies the enamel-safe hydrogen peroxide serum for exceptional, quicker and less peroxide-dependent whitening results. The Pen allows you to apply the enamel-safe serum that removes stains. [Learn More About Whitening](https://www.colgate.com/en-us/optic-white) ### Colgate® MaxFresh® Cooling Crystals Cooling crystals in our MaxFresh toothpaste are uniquely formulated with an innovative odor-neutralizing technology that helps destroy odor and fight lingering food aftertaste. The crystals dissolve completely when you brush providing the cooling effect. [Learn More About MaxFresh](https://www.colgate.com/en-us/optic-white) ### Colgate® MaxFresh® Cooling Crystals Cooling crystals in our MaxFresh toothpaste are uniquely formulated with an innovative odor-neutralizing technology that helps destroy odor and fight lingering food aftertaste. The crystals dissolve completely when you brush providing the cooling effect. [Learn More About MaxFresh](https://www.colgate.com/en-us/optic-white) ### Colgate® MaxFresh® Cooling Crystals Cooling crystals in our MaxFresh toothpaste are uniquely formulated with an innovative odor-neutralizing technology that helps destroy odor and fight lingering food aftertaste. The crystals dissolve completely when you brush providing the cooling effect. [Learn More About MaxFresh](https://www.colgate.com/en-us/max-fresh) ### Colgate® MaxFresh® Cooling Crystals Cooling crystals in our MaxFresh toothpaste are uniquely formulated with an innovative odor-neutralizing technology that helps destroy odor and fight lingering food aftertaste. The crystals dissolve completely when you brush providing the cooling effect. [Learn More About MaxFresh](https://www.colgate.com/en-us/max-fresh) [ History & Purpose Creating a healthier and brighter future, one smile at a time](https://www.colgate.com/en-us/mission/history-and-purpose) [ Oral Health Commitment Leading the way for healthy smiles across the world](https://www.colgate.com/en-us/mission/oral-health-commitment) [ Environmental Impact We’re committed to reduce our environmental impact](https://www.colgate.com/en-us/mission/environmental-impact) - [Products](https://www.colgate.com/en-us/products) - [Oral Health](https://www.colgate.com/en-us/oral-health) - [Mission](https://www.colgate.com/en-us/mission/history-and-purpose) - [Oral Health Check](https://www.colgate.com/en-us/oral-health-quiz) - [Product Match](https://www.colgate.com/en-us/product-match-tool) - [Sign Up](https://www.colgate.com/en-us/mission/science-and-innovation#lightbox) - [Contact Us](https://www.colgatepalmolive.com/en-us/contact-us) - [US (EN)](https://www.colgate.com/en-us/locations) - [ColgateProfessional.com](https://www.colgateprofessional.com/) - [Shop.Colgate.com](https://shop.colgate.com/) [ © 2024 Colgate-Palmolive Company. 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1. [Oral Health and Dental Care \| Colgate®](https://www.colgate.com/en-us) 2. [Mission](https://www.colgate.com/en-us/mission) 3. Science and Innovation  ## Changing the world, one breakthrough at a time ## Changing the world, one breakthrough at a time With over 200 years of experience, we are the most trusted oral care products company across the globe. We’ve earned that trust because we invest more in research and development than any other oral healthcare company. Our experts use cutting-edge technology to create the scientific-led products you need for your best, healthiest smile. Our Colgate technology campus Our team of over 900, who work at our state-of-the-art research and development facility in New Jersey, conducts over 200 clinical trials and files around 100 patents each year. Using science to innovate lets us understand the true health benefits of our products and it helps us to develop new products to address emerging conditions. Watch the video to learn more about the Volpe Clinical Research Center. Groundbreaking science creates groundbreaking products Our scientific research and development has led to more patented innovations than any other oral care company. Here are some of the latest: