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URLhttps://www.cidrap.umn.edu/pfizer-submits-data-fda-covid-vaccine-young-kids
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Meta TitlePfizer submits data to FDA on COVID vaccine in young kids | CIDRAP
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Pfizer and BioNTech submitted initial data from a phase 2/3 trial of their mRNA COVID-19 vaccine for children ages 5 to 11 years to the Food and Drug Administration (FDA), and said an application for emergency use authorization of the vaccine in that age-group will likely follow in the coming weeks. On Sep 20, the company shared promising results in children in that age range of two doses of the mRNA vaccine, which contains 10 micrograms (μg) of active ingredient, compared with 30 μg contained in the currently FDA-approved vaccine. Pfizer said the company will have data on vaccines in children ages 6 months to 2 years, and 2 years to 5 years, as soon as the fourth quarter of 2021. Children under age 5 received a lower 3-μg dose for each injection in the phase 2/3 study, the company said. Children 11 and younger are the only group of Americans not yet eligible for COVID-19 vaccination, and pediatric cases of the virus have increased significantly since the Delta (B1617.2) variant became the dominant strain in the United States this summer. For the fifth consecutive week, more than 200,000 pediatric cases were reported across the country during the week of Sep 16 to the 23. The latest update from the American Academy of Pediatrics (AAP) shows that nearly 207,000 child COVID-19 cases were reported last week. "Since the pandemic began, children represented 16.0% of total cumulated cases. For the week ending September 23, children were 26.7% of reported weekly COVID-19 cases (children, under age 18, make up 22.2% of the US population)," the AAP said. More New York health workers get vaccinated The United States reported 185,088 new COVID-19 cases yesterday and 2,394 deaths, according to the Johns Hopkins COVID-19  tracker . The 7-day average of new daily cases is 117,966, with 2,052 daily deaths, according to the New York Times tracker . The Times reports that thousands of healthcare workers across New York state got inoculated against COVID-19 ahead of yesterday's deadline. The statewide vaccination rate for hospital employees rose to 92% by last night, up from 84% 5 days ago. All eyes will be on New York in the coming days, as its mandatory vaccine requirement for hospital and healthcare employees is one of the largest and strictest in the country. A similar mandate will go into effect Sep 30 in California. But thousands of nurses, aides, and other employees in New York chose to lose their jobs rather than get vaccinated. New York Gov. Kathy Hochul yesterday signed an executive order that will allow healthcare workers from other states and countries to begin practicing in New York, the Washington Post reports. The governor has also said she may use the National Guard to deliver healthcare in the state. Delta a factor in getting vaccinated Thirty-nine percent of adults who got vaccinated since Jun 1 cite the Delta variant as a major reason for doing so, followed by reports of local hospitals filling up (38%) and knowing someone who became seriously ill or died (36%), according to the latest survey from the Kaiser Family Foundation (KFF). Among the unvaccinated, 71% said the news about booster shots is a sign the vaccines aren't working. According to the KFF, "The largest remaining gap is between political partisans, with 90 percent of Democrats reporting they have gotten at least one dose, compared to 58 percent of Republicans." Other US developments An Arizona judge ruled yesterday that the state's law banning public schools from issuing mask mandates is unconstitutional, NPR reports . The law was set to take effect tomorrow. The nation's business economists are expecting slower growth this year due to the Delta variant, CBS News reports . Pfizer yesterday said it has started a phase 2/3 study of an oral prophylactic against COVID that consists of a low dose of the HIV protease inhibitor ritonavir given with an investigational antiviral candidate.
Markdown
Menu - [News](https://www.cidrap.umn.edu/) - [Topics & ProjectsToggle submenu](https://www.cidrap.umn.edu/pfizer-submits-data-fda-covid-vaccine-young-kids#mm-2) - [Antimicrobial Resistance](https://www.cidrap.umn.edu/antimicrobial-stewardship) - [COVID-19](https://www.cidrap.umn.edu/covid-19) - [Chronic Wasting Disease](https://www.cidrap.umn.edu/chronic-wasting-disease) - [Influenza](https://www.cidrap.umn.edu/influenza-general) - [Resilient Drug Supply](https://www.cidrap.umn.edu/resilient-drug-supply) - [Coronavirus Vaccines Roadmap](https://www.cidrap.umn.edu/coronavirus-vaccines-roadmap) - [Influenza Vaccines Roadmap](https://ivr.cidrap.umn.edu/ "(opens in a new window)") - [Roadmaps for Priority Pathogens](https://www.cidrap.umn.edu/roadmap-development) - [Vaccine Integrity Project](https://www.cidrap.umn.edu/vaccine-integrity-project) - [CIDRAP Leadership Forum](https://www.cidrap.umn.edu/forum "CIDRAP Leadership Forum") - . - . - [All Topics A-Z](https://www.cidrap.umn.edu/infectious-disease-topics) - [PodcastsToggle submenu](https://www.cidrap.umn.edu/pfizer-submits-data-fda-covid-vaccine-young-kids#mm-3) - [Antimicrobial Stewardship](https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you) - [Chronic Wasting Disease](https://www.cidrap.umn.edu/chronic-wasting-disease/cwd-pod) - [Osterholm Update](https://www.cidrap.umn.edu/osterholm-update) - [Newsletters](https://www.cidrap.umn.edu/newsletter) - [AboutToggle submenu](https://www.cidrap.umn.edu/pfizer-submits-data-fda-covid-vaccine-young-kids#mm-4) - [About CIDRAP](https://www.cidrap.umn.edu/about-cidrap) - [CIDRAP in the News](https://www.cidrap.umn.edu/cidrap-news) - [Our Staff](https://www.cidrap.umn.edu/about-us/cidrap-staff) - [Our Director](https://www.cidrap.umn.edu/michael-t-osterholdm-phd-mph) - [Osterholm in the Press](https://www.cidrap.umn.edu/osterholm-quotes) - [Shop Merchandise](https://www.mnalumnimarket.com/collections/cidrap?utm_source=website&utm_medium=website&utm_campaign=CIDRAPdonate&utm_content=CIDRAP "(opens in a new window)") - [Contact Us](https://www.cidrap.umn.edu/contact-us) - [Donate](https://www.cidrap.umn.edu/support) [Skip to main content](https://www.cidrap.umn.edu/pfizer-submits-data-fda-covid-vaccine-young-kids#main-content) [Main navigation](https://www.cidrap.umn.edu/pfizer-submits-data-fda-covid-vaccine-young-kids#main-nav) **University of Minnesota** http://twin-cities.umn.edu/ 612-625-5000 [Go to the U of M home page](http://twin-cities.umn.edu/ "(opens in a new window)") [![Home](https://www.cidrap.umn.edu/themes/custom/cidrap_theme/logo-internal.svg)](https://www.cidrap.umn.edu/ "Home") ## Main navigation - [News](https://www.cidrap.umn.edu/) - - [Antimicrobial Resistance](https://www.cidrap.umn.edu/antimicrobial-stewardship) - [COVID-19](https://www.cidrap.umn.edu/covid-19) - [Chronic Wasting Disease](https://www.cidrap.umn.edu/chronic-wasting-disease) - [Influenza](https://www.cidrap.umn.edu/influenza-general) - [Resilient Drug Supply](https://www.cidrap.umn.edu/resilient-drug-supply) - [All Topics A-Z](https://www.cidrap.umn.edu/infectious-disease-topics) - [Coronavirus Vaccines Roadmap](https://www.cidrap.umn.edu/coronavirus-vaccines-roadmap) - [Influenza Vaccines Roadmap](https://ivr.cidrap.umn.edu/ "(opens in a new window)") - [Roadmaps for Priority Pathogens](https://www.cidrap.umn.edu/roadmap-development) - [Vaccine Integrity Project](https://www.cidrap.umn.edu/vaccine-integrity-project) - [CIDRAP Leadership Forum](https://www.cidrap.umn.edu/forum "CIDRAP Leadership Forum") - . - . Topics & Projects - - [Antimicrobial Stewardship](https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you) - [Chronic Wasting Disease](https://www.cidrap.umn.edu/chronic-wasting-disease/cwd-pod) - [Osterholm Update](https://www.cidrap.umn.edu/osterholm-update) Podcasts - [Newsletters](https://www.cidrap.umn.edu/newsletter) - - [About CIDRAP](https://www.cidrap.umn.edu/about-cidrap) - [CIDRAP in the News](https://www.cidrap.umn.edu/cidrap-news) - [Our Staff](https://www.cidrap.umn.edu/about-us/cidrap-staff) - [Our Director](https://www.cidrap.umn.edu/michael-t-osterholdm-phd-mph) - [Osterholm in the Press](https://www.cidrap.umn.edu/osterholm-quotes) - [Shop Merchandise](https://www.mnalumnimarket.com/collections/cidrap?utm_source=website&utm_medium=website&utm_campaign=CIDRAPdonate&utm_content=CIDRAP "(opens in a new window)") - [Contact Us](https://www.cidrap.umn.edu/contact-us) About Search - [Support](https://www.cidrap.umn.edu/support) [Menu](https://www.cidrap.umn.edu/pfizer-submits-data-fda-covid-vaccine-young-kids#off-canvas "Menu") # Pfizer submits data to FDA on COVID vaccine in young kids Stephanie Soucheray \| News Reporter \| CIDRAP News September 28, 2021 [COVID-19](https://www.cidrap.umn.edu/covid-19) ![Young girl getting vaccine](https://www.cidrap.umn.edu/sites/default/files/styles/article_detail/public/images/news/young_girl_getting_vaccine-crop.jpg?itok=ltM7HNpB) ![Young girl getting vaccine](https://www.cidrap.umn.edu/sites/default/files/styles/thumbnail/public/media/article/young_girl_getting_vaccine.jpg?itok=Ehmwn3x1) > SeventyFour / iStock Share Pfizer and BioNTech [submitted initial data](https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-submit-initial-data-us-fda-pivotal "(opens in a new window)") from a phase 2/3 trial of their mRNA COVID-19 vaccine for children ages 5 to 11 years to the Food and Drug Administration (FDA), and said an application for emergency use authorization of the vaccine in that age-group will likely follow in the coming weeks. On Sep 20, the company shared promising results in children in that age range of two doses of the mRNA vaccine, which contains 10 micrograms (μg) of active ingredient, compared with 30 μg contained in the currently FDA-approved vaccine. Pfizer said the company will have data on vaccines in children ages 6 months to 2 years, and 2 years to 5 years, as soon as the fourth quarter of 2021. Children under age 5 received a lower 3-μg dose for each injection in the phase 2/3 study, the company said. Children 11 and younger are the only group of Americans not yet eligible for COVID-19 vaccination, and pediatric cases of the virus have increased significantly since the Delta (B1617.2) variant became the dominant strain in the United States this summer. For the fifth consecutive week, more than 200,000 pediatric cases were reported across the country during the week of Sep 16 to the 23. The latest [update](https://www.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/children-and-covid-19-state-level-data-report/ "(opens in a new window)") from the American Academy of Pediatrics (AAP) shows that nearly 207,000 child COVID-19 cases were reported last week. "Since the pandemic began, children represented 16.0% of total cumulated cases. For the week ending September 23, children were 26.7% of reported weekly COVID-19 cases (children, under age 18, make up 22.2% of the US population)," the AAP said. ### More New York health workers get vaccinated The United States reported 185,088 new COVID-19 cases yesterday and 2,394 deaths, according to the Johns Hopkins COVID-19 [tracker](https://coronavirus.jhu.edu/data/cumulative-cases "(opens in a new window)"). The 7-day average of new daily cases is 117,966, with 2,052 daily deaths, according to the *New York Times* [tracker](https://www.nytimes.com/interactive/2021/us/covid-cases.html "(opens in a new window)"). The *Times* reports that [thousands of healthcare workers](https://www.nytimes.com/live/2021/09/28/world/covid-coronavirus-vaccine#health-care-workers-in-new-york-rush-to-get-vaccinated-averting-a-staffing-crisis "(opens in a new window)") across New York state got inoculated against COVID-19 ahead of yesterday's deadline. The statewide vaccination rate for hospital employees rose to 92% by last night, up from 84% 5 days ago. All eyes will be on New York in the coming days, as its mandatory vaccine requirement for hospital and healthcare employees is one of the largest and strictest in the country. A similar mandate will go into effect Sep 30 in California. But thousands of nurses, aides, and other employees in New York chose to lose their jobs rather than get vaccinated. New York Gov. Kathy Hochul yesterday signed an executive order that will allow healthcare workers from other states and countries to begin practicing in New York, the *[Washington Post](https://www.washingtonpost.com/business/2021/09/28/new-york-vaccine-mandate-deadline/ "(opens in a new window)")* reports. The governor has also said she may use the National Guard to deliver healthcare in the state. ### Delta a factor in getting vaccinated Thirty-nine percent of adults who got vaccinated since Jun 1 cite the Delta variant as a major reason for doing so, followed by reports of local hospitals filling up (38%) and knowing someone who became seriously ill or died (36%), according to the latest [survey](https://www.kff.org/coronavirus-covid-19/press-release/surging-delta-variant-cases-hospitalizations-and-deaths-are-biggest-drivers-of-recent-uptick-in-u-s-covid-19-vaccination-rates/ "(opens in a new window)") from the Kaiser Family Foundation (KFF). Among the unvaccinated, 71% said the news about booster shots is a sign the vaccines aren't working. According to the KFF, "The largest remaining gap is between political partisans, with 90 percent of Democrats reporting they have gotten at least one dose, compared to 58 percent of Republicans." ### Other US developments - An Arizona judge ruled yesterday that the state's law banning public schools from issuing mask mandates is unconstitutional, [NPR reports](https://www.npr.org/2021/09/27/1041044436/just-before-taking-effect-arizonas-school-mask-mandate-ban-ruled-unconstitutiona "(opens in a new window)"). The law was set to take effect tomorrow. - The nation's business economists are expecting slower growth this year due to the Delta variant, [CBS News reports](https://www.cbsnews.com/news/delta-variant-covid-19-economy/ "(opens in a new window)"). - Pfizer [yesterday](https://www.pfizer.com/news/press-release/press-release-detail/pfizer-starts-global-phase-23-epic-pep-study-novel-covid-19 "(opens in a new window)") said it has started a phase 2/3 study of an oral prophylactic against COVID that consists of a low dose of the HIV protease inhibitor ritonavir given with an investigational antiviral candidate. ## Related news Previous Next [Trial: Paxlovid retreatment after COVID rebound tied to faster drop in viral RNA but no clinical benefit October 2, 2025 Mary Van Beusekom ![Man taking 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vaccinated](https://www.cidrap.umn.edu/sites/default/files/styles/hand_curated_related_teaser/public/article/Viewpoint%20pic.jpg?itok=j4fpk9t6)](https://www.cidrap.umn.edu/childhood-vaccines/viewpoint-what-we-don-t-see-about-vaccines-could-hurt-us) ## This week's top reads 1. [Another Canadian baby dies from measles as South Carolina reports outbreak In other developments, South Carolina suspects community transmission in an outbreak in the Upstate region. Lisa Schnirring October 3, 2025](https://www.cidrap.umn.edu/measles/another-canadian-baby-dies-measles-south-carolina-reports-outbreak) 2. [COVID-19 infection associated with increased risk of new-onset vascular dementia in older adults Prior COVID-19 infection was associated with a 41% increased risk of all-cause dementia. Stephanie Soucheray October 2, 2025](https://www.cidrap.umn.edu/covid-19/covid-19-infection-associated-increased-risk-new-onset-vascular-dementia-older-adults) 3. [Nearly 1 in 3 adults with severe long COVID have rare heart-rhythm disorder, data suggest In contrast, the condition affected less than 1% of the Swedish population before the pandemic. Mary Van Beusekom October 6, 2025 ![Woman with dizziness](https://www.cidrap.umn.edu/sites/default/files/styles/article_teaser/public/article/POTS.png?itok=bYWpAo6U)](https://www.cidrap.umn.edu/covid-19/nearly-1-3-adults-severe-long-covid-have-rare-heart-rhythm-disorder-data-suggest) 4. [Past surgeons general warn HHS Secretary Kennedy must go The group warns that under Kennedy more childhood vaccines will be in jeopardy. Stephanie Soucheray October 7, 2025 ![RFK waving at rally](https://www.cidrap.umn.edu/sites/default/files/styles/article_teaser/public/article/53952717706_a61b74db5e_c.jpg?itok=ZcT6DTfZ)](https://www.cidrap.umn.edu/childhood-vaccines/past-surgeons-general-warn-hhs-secretary-kennedy-must-go) 5. [CDC announces changes to COVID, childhood vaccines, touting 'informed consent' The CDC recommends that toddlers receive the varicella (chickenpox) vaccine as a standalone immunization. Stephanie Soucheray October 6, 2025 ![informed patient consent ](https://www.cidrap.umn.edu/sites/default/files/styles/article_teaser/public/article/iStock-2190554549.jpg?itok=MFe9q0tT)](https://www.cidrap.umn.edu/covid-19/cdc-announces-changes-covid-childhood-vaccines-touting-informed-consent) 6. [Two investigations reveal how resistant bacteria may have spread from pets to people Molecular analysis and epidemiologic detective work helped uncover a hidden One Health connection between human and animal clusters of multidrug-resistant bacterial infections. Chris Dall October 2, 2025 ![Dog being treated at animal hospital](https://www.cidrap.umn.edu/sites/default/files/styles/article_teaser/public/article/iStock-1516371036.jpg?itok=JhTE1wjf)](https://www.cidrap.umn.edu/antimicrobial-stewardship/two-investigations-reveal-how-resistant-bacteria-may-have-spread-pets) 7. [CIDRAP Op-Ed: Why the CDC director is wrong about the MMR vaccine A call to develop separate measles, mumps, and rubella vaccines to replace the combined MMR shot is not backed by evidence. Jake Scott, MD October 9, 2025 ![Three syringes](https://www.cidrap.umn.edu/sites/default/files/styles/article_teaser/public/article/Three%20intersecting%20syringes.jpg?itok=qvSMpvmE)](https://www.cidrap.umn.edu/childhood-vaccines/cidrap-op-ed-why-cdc-director-wrong-about-mmr-vaccine) 8. [Locally transmitted US malaria cases highlight increased risk, CDC report suggests The 10 locally transmitted malaria cases identified in 4 states in the summer of 2023 were the first in the US since 2023. Chris Dall October 7, 2025 ![Anopheles mosquito](https://www.cidrap.umn.edu/sites/default/files/styles/article_teaser/public/article/iStock-123135918.jpg?itok=NdxCbNtR)](https://www.cidrap.umn.edu/malaria/locally-transmitted-us-malaria-cases-highlight-increased-risk-cdc-report-suggests) 9. [Flurry of H5N1 activity noted in commercial poultry, wild birds Over the last 30 days, highly pathogenic avian influenza (HPAI) has been confirmed in 38 flocks. Stephanie Soucheray October 9, 2025 ![turkeys in cages](https://www.cidrap.umn.edu/sites/default/files/styles/article_teaser/public/article/iStock-1138217573.jpg?itok=1u7X_D2X)](https://www.cidrap.umn.edu/avian-influenza-bird-flu/flurry-h5n1-activity-noted-commercial-poultry-wild-birds) 10. [More measles cases confirmed in South Carolina, Michigan as US total climbs to 1,563 Michigan has reported 28 cases this year. 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