ℹ️ Skipped - page is already crawled
| Filter | Status | Condition | Details |
|---|---|---|---|
| HTTP status | PASS | download_http_code = 200 | HTTP 200 |
| Age cutoff | PASS | download_stamp > now() - 6 MONTH | 1.4 months ago |
| History drop | PASS | isNull(history_drop_reason) | No drop reason |
| Spam/ban | PASS | fh_dont_index != 1 AND ml_spam_score = 0 | ml_spam_score=0 |
| Canonical | PASS | meta_canonical IS NULL OR = '' OR = src_unparsed | Not set |
| Property | Value |
|---|---|
| URL | https://www.cdc.gov/me-cfs/signs-symptoms/index.html |
| Last Crawled | 2026-03-02 18:49:55 (1 month ago) |
| First Indexed | 2024-05-20 15:38:21 (1 year ago) |
| HTTP Status Code | 200 |
| Meta Title | Symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | ME/CFS | CDC |
| Meta Description | ME/CFS has 5 core symptoms. Diagnosis requires 3 main symptoms and at least 1 other symptom |
| Meta Canonical | null |
| Boilerpipe Text | Myalgic encephalomyelitis/chronic fatigue syndrome symptoms are common in many other illnesses.
There is no test to confirm ME/CFS. This makes it hard to diagnose.
Symptoms are unpredictable and may change or come and go over time.
However, a combination of core symptoms are used to diagnose ME/CFS.
Primary symptoms
ME/CFS has five core symptoms. You must have three main ME/CFS symptoms and at least one of the other two symptoms to be diagnosed with ME/CFS.
Less ability to do activities and fatigue (required)
People with ME/CFS have a much lower ability to do activities they could do before they got sick. This limitation comes with fatigue and lasts six months or longer.
The fatigue:
Can be severe
Isn't caused by an unusually difficult activity
Isn't relieved by sleep or rest
Worse symptoms after activity (required)
People with ME/CFS experience a worsening of their symptoms after any type of activity - physical or mental. These activities wouldn't have been a problem before they became ill. This is called Post-Exertional Malaise (PEM).
PEM can lead to a cycle of "pushing" to do more, followed by "crashing." During a crash, people with ME/CFS may have a variety of symptoms. These can include difficulty thinking, problems sleeping, sore throat, headaches, feeling dizzy, or severe tiredness.
It may take days, weeks, or longer to recover from a crash. Some people may be confined to bed or the house. As examples:
Attending a school event may leave someone house-bound for days.
Grocery shopping may require a nap in the car before driving home.
Doing errands may require getting a ride home.
Showering may leave someone bed-bound for days.
Working may mean spending nights and weekends recovering.
Sleep Problems (Required)
People with ME/CFS may not feel better or less tired, even after a full night's sleep. Some may have problems falling asleep or staying asleep.
Additional symptoms (At least 1 required)
In addition to the three required symptoms above, one of the following two symptoms is needed to be diagnosed with ME/CFS.
Memory and thinking problems
Most people with ME/CFS have trouble thinking quickly, remembering things, and paying attention to details. People with ME/CFS often say they have “brain fog” to describe this problem. This is because they feel “stuck in a fog” and not able to think clearly.
Problems being upright
People with ME/CFS often report their symptoms get worse when they are standing or sitting upright. This is called orthostatic intolerance.
People with ME/CFS may be lightheaded, dizzy, weak, or faint while standing or sitting up. They may have vision changes like blurring or seeing spots.
Other common symptoms
Many but not all people with ME/CFS have other symptoms.
Pain
is very common in people with ME/CFS. The type of pain, where it occurs, and how bad it is varies a lot. The pain people with ME/CFS feel is not caused by an injury. The most common types of pain in ME/CFS are:
Muscle pain and aches
Joint pain without swelling or redness
Headaches, either new or worsening
Some people with ME/CFS may also have:
Tender lymph nodes in the neck or armpits
Frequent sore throat
Digestive issues, like irritable bowel syndrome
Chills and night sweats
Allergies or sensitivities to foods, odors, chemicals, light and noise
Muscle weakness
Shortness of breath
Irregular heartbeat
May 10, 2024
Sources
Disclaimer: This website is for informational purposes only. The information provided on this website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. |
| Markdown | [Skip directly to site content](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#content) [Skip directly to search](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#cdc-search) [Skip directly to On This Page](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#first-on-this-page)
 An official website of the United States government
[Here's how you know](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#gov-notice)

**Official websites use .gov**
A **.gov** website belongs to an official government organization in the United States.

**Secure .gov websites use HTTPS**
A **lock** ( ) or **https://** means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.
[](https://www.cdc.gov/)
[Myalgic Encephalomyelitis/Chronic Fatigue Syndrome](https://www.cdc.gov/me-cfs/about/index.html)
Explore This Topic
[For Everyone](https://www.cdc.gov/me-cfs/site.html#gen)
- [About ME/CFS](https://www.cdc.gov/me-cfs/about/index.html)
- [ME/CFS Symptoms](https://www.cdc.gov/me-cfs/signs-symptoms/index.html)
- [ME/CFS Causes](https://www.cdc.gov/me-cfs/causes/index.html)
- [Diagnosis of ME/CFS](https://www.cdc.gov/me-cfs/diagnosis/index.html)
- [Managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome](https://www.cdc.gov/me-cfs/management/index.html)
- [Living with ME/CFS](https://www.cdc.gov/me-cfs/living-with/index.html)
- [Patient Toolkit](https://www.cdc.gov/me-cfs/toolkit/index.html)
- [Stakeholder Engagement and Communication (SEC) calls](https://www.cdc.gov/me-cfs/events/index.html)
- [ME/CFS in Children](https://www.cdc.gov/me-cfs/children/index.html)
- [Disability and ME/CFS](https://www.cdc.gov/me-cfs/disability/index.html)
- [ME/CFS Awareness Day](https://www.cdc.gov/me-cfs/awareness-day/index.html)
- [Information on CDC's ME/CFS Program](https://www.cdc.gov/me-cfs/programs/index.html)
- [View all](https://www.cdc.gov/me-cfs/site.html#gen)
[Health Care Providers](https://www.cdc.gov/me-cfs/site.html#hcp)
- [Clinical Overview](https://www.cdc.gov/me-cfs/hcp/clinical-overview/index.html)
- [Diagnosing ME/CFS](https://www.cdc.gov/me-cfs/hcp/diagnosis/index.html)
- [Clinical Care and Treatment](https://www.cdc.gov/me-cfs/hcp/clinical-care/index.html)
- [Healthcare Provider Toolkit](https://www.cdc.gov/me-cfs/hcp/toolkit/index.html)
- [Training: Medscape Continuing Medical Education (CME)](https://www.cdc.gov/me-cfs/hcp/training/index.html)
- [View all](https://www.cdc.gov/me-cfs/site.html#hcp)
[Home](https://www.cdc.gov/me-cfs/about/index.html)
[](https://www.cdc.gov/)
[*search*](https://www.cdc.gov/me-cfs/signs-symptoms/index.html)
[ME/CFS](https://www.cdc.gov/me-cfs/about/index.html)
Menu
For Everyone
- [About ME/CFS](https://www.cdc.gov/me-cfs/about/index.html)
- [ME/CFS Symptoms](https://www.cdc.gov/me-cfs/signs-symptoms/index.html)
- [ME/CFS Causes](https://www.cdc.gov/me-cfs/causes/index.html)
- [Diagnosis of ME/CFS](https://www.cdc.gov/me-cfs/diagnosis/index.html)
- [Managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome](https://www.cdc.gov/me-cfs/management/index.html)
- [Living with ME/CFS](https://www.cdc.gov/me-cfs/living-with/index.html)
- [Patient Toolkit](https://www.cdc.gov/me-cfs/toolkit/index.html)
- [Stakeholder Engagement and Communication (SEC) calls](https://www.cdc.gov/me-cfs/events/index.html)
- [View All](https://www.cdc.gov/me-cfs/site.html#gen)
Health Care Providers
- [Clinical Overview](https://www.cdc.gov/me-cfs/hcp/clinical-overview/index.html)
- [Diagnosing ME/CFS](https://www.cdc.gov/me-cfs/hcp/diagnosis/index.html)
- [Clinical Care and Treatment](https://www.cdc.gov/me-cfs/hcp/clinical-care/index.html)
- [Healthcare Provider Toolkit](https://www.cdc.gov/me-cfs/hcp/toolkit/index.html)
- [Training: Medscape Continuing Medical Education (CME)](https://www.cdc.gov/me-cfs/hcp/training/index.html)
- [View All](https://www.cdc.gov/me-cfs/site.html#hcp)
[ME/CFS](https://www.cdc.gov/me-cfs/about/index.html)
[About ME/CFS](https://www.cdc.gov/me-cfs/about/index.html) [ME/CFS Symptoms](https://www.cdc.gov/me-cfs/signs-symptoms/index.html) [ME/CFS Causes](https://www.cdc.gov/me-cfs/causes/index.html) [Diagnosis of ME/CFS](https://www.cdc.gov/me-cfs/diagnosis/index.html) [Managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome](https://www.cdc.gov/me-cfs/management/index.html) [Living with ME/CFS](https://www.cdc.gov/me-cfs/living-with/index.html) [Patient Toolkit](https://www.cdc.gov/me-cfs/toolkit/index.html) [Stakeholder Engagement and Communication (SEC) calls](https://www.cdc.gov/me-cfs/events/index.html) [View Menu](https://www.cdc.gov/me-cfs/signs-symptoms/index.html)

For Everyone
May 10, 2024
[Español](https://www.cdc.gov/me-cfs/es/signs-symptoms/sintomas-de-la-encefalomielitis-mialgica-sindrome-de-fatiga-cronica.html)
# Symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
## Key points
- Myalgic encephalomyelitis/chronic fatigue syndrome symptoms are common in many other illnesses.
- There is no test to confirm ME/CFS. This makes it hard to diagnose.
- Symptoms are unpredictable and may change or come and go over time.
- However, a combination of core symptoms are used to diagnose ME/CFS.

## Primary symptoms
ME/CFS has five core symptoms. You must have three main ME/CFS symptoms and at least one of the other two symptoms to be diagnosed with ME/CFS.
### Less ability to do activities and fatigue (required)
People with ME/CFS have a much lower ability to do activities they could do before they got sick. This limitation comes with fatigue and lasts six months or longer.
The fatigue:
- Can be severe
- Isn't caused by an unusually difficult activity
- Isn't relieved by sleep or rest
### Worse symptoms after activity (required)
People with ME/CFS experience a worsening of their symptoms after any type of activity - physical or mental. These activities wouldn't have been a problem before they became ill. This is called Post-Exertional Malaise (PEM).
PEM can lead to a cycle of "pushing" to do more, followed by "crashing." During a crash, people with ME/CFS may have a variety of symptoms. These can include difficulty thinking, problems sleeping, sore throat, headaches, feeling dizzy, or severe tiredness.
It may take days, weeks, or longer to recover from a crash. Some people may be confined to bed or the house. As examples:
- Attending a school event may leave someone house-bound for days.
- Grocery shopping may require a nap in the car before driving home.
- Doing errands may require getting a ride home.
- Showering may leave someone bed-bound for days.
- Working may mean spending nights and weekends recovering.
### Sleep Problems (Required)
People with ME/CFS may not feel better or less tired, even after a full night's sleep. Some may have problems falling asleep or staying asleep.
## Additional symptoms (At least 1 required)
In addition to the three required symptoms above, one of the following two symptoms is needed to be diagnosed with ME/CFS.
### Memory and thinking problems
Most people with ME/CFS have trouble thinking quickly, remembering things, and paying attention to details. People with ME/CFS often say they have “brain fog” to describe this problem. This is because they feel “stuck in a fog” and not able to think clearly.
### Problems being upright
People with ME/CFS often report their symptoms get worse when they are standing or sitting upright. This is called orthostatic intolerance.
People with ME/CFS may be lightheaded, dizzy, weak, or faint while standing or sitting up. They may have vision changes like blurring or seeing spots.
## Other common symptoms
Many but not all people with ME/CFS have other symptoms.
**Pain** is very common in people with ME/CFS. The type of pain, where it occurs, and how bad it is varies a lot. The pain people with ME/CFS feel is not caused by an injury. The most common types of pain in ME/CFS are:
- Muscle pain and aches
- Joint pain without swelling or redness
- Headaches, either new or worsening
Some people with ME/CFS may also have:
- Tender lymph nodes in the neck or armpits
- Frequent sore throat
- Digestive issues, like irritable bowel syndrome
- Chills and night sweats
- Allergies or sensitivities to foods, odors, chemicals, light and noise
- Muscle weakness
- Shortness of breath
- Irregular heartbeat
## On This Page
- [Primary symptoms](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#cdc_symptoms_section_1-primary-symptoms)
- [Additional symptoms (At least 1 required)](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#cdc_symptoms_section_2-additional-symptoms-at-least-1-required)
- [Other common symptoms](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#cdc_symptoms_section_3-other-common-symptoms)
## Related Pages
- [About ME/CFS](https://www.cdc.gov/me-cfs/about/index.html)
- [ME/CFS Causes](https://www.cdc.gov/me-cfs/causes/index.html)
- [Diagnosis of ME/CFS](https://www.cdc.gov/me-cfs/diagnosis/index.html)
- [Managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome](https://www.cdc.gov/me-cfs/management/index.html)
- [Living with ME/CFS](https://www.cdc.gov/me-cfs/living-with/index.html)
[View All ME/CFS](https://www.cdc.gov/me-cfs/site.html#gen)
[ME/CFS Causes](https://www.cdc.gov/me-cfs/causes/index.html)
May 10, 2024
[Sources](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#content-sources) [Print](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#print) [Share](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#share)
[Facebook](https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.cdc.gov%2Fme-cfs%2Fsigns-symptoms%2Findex.html "Share to Facebook") [LinkedIn](https://www.linkedin.com/shareArticle?url=https%3A%2F%2Fwww.cdc.gov%2Fme-cfs%2Fsigns-symptoms%2Findex.html&title=Symptoms%20of%20Myalgic%20Encephalomyelitis%2FChronic%20Fatigue%20Syndrome "Share to LinkedIn") [Twitter](http://twitter.com/share?url=https%3A%2F%2Fwww.cdc.gov%2Fme-cfs%2Fsigns-symptoms%2Findex.html&text=Symptoms%20of%20Myalgic%20Encephalomyelitis%2FChronic%20Fatigue%20Syndrome "Share to Twitter") [Syndicate](https://tools.cdc.gov/medialibrary/index.aspx#/sharecontent/https://https://www.cdc.gov/me-cfs/signs-symptoms/index.html "Embed this Page")
Content Source:
[National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)](https://www.cdc.gov/ncezid/index.html)
Sources
- Disclaimer: This website is for informational purposes only. The information provided on this website is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
## Related Pages
- [About ME/CFS](https://www.cdc.gov/me-cfs/about/index.html)
- [ME/CFS Causes](https://www.cdc.gov/me-cfs/causes/index.html)
- [Diagnosis of ME/CFS](https://www.cdc.gov/me-cfs/diagnosis/index.html)
- [Managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome](https://www.cdc.gov/me-cfs/management/index.html)
- [Living with ME/CFS](https://www.cdc.gov/me-cfs/living-with/index.html)
[View All ME/CFS](https://www.cdc.gov/me-cfs/site.html#gen)
Back to Top
## [ME/CFS](https://www.cdc.gov/me-cfs/about/index.html)
ME/CFS is a serious, debilitating illness that makes it hard for people to do activities they could previously do without difficulty.
[View All](https://www.cdc.gov/me-cfs/site.html)
### [For Everyone](https://www.cdc.gov/me-cfs/site.html#gen)
- [About ME/CFS](https://www.cdc.gov/me-cfs/about/index.html)
- [ME/CFS Symptoms](https://www.cdc.gov/me-cfs/signs-symptoms/index.html)
- [ME/CFS Causes](https://www.cdc.gov/me-cfs/causes/index.html)
- [Diagnosis of ME/CFS](https://www.cdc.gov/me-cfs/diagnosis/index.html)
- [Managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome](https://www.cdc.gov/me-cfs/management/index.html)
- [Living with ME/CFS](https://www.cdc.gov/me-cfs/living-with/index.html)
- [Patient Toolkit](https://www.cdc.gov/me-cfs/toolkit/index.html)
- [Stakeholder Engagement and Communication (SEC) calls](https://www.cdc.gov/me-cfs/events/index.html)
- [View all](https://www.cdc.gov/me-cfs/site.html#gen)
### [Health Care Providers](https://www.cdc.gov/me-cfs/site.html#hcp)
- [Clinical Overview](https://www.cdc.gov/me-cfs/hcp/clinical-overview/index.html)
- [Diagnosing ME/CFS](https://www.cdc.gov/me-cfs/hcp/diagnosis/index.html)
- [Clinical Care and Treatment](https://www.cdc.gov/me-cfs/hcp/clinical-care/index.html)
- [View All](https://www.cdc.gov/me-cfs/site.html#hcp)
[Sign up for Email Updates](https://tools.cdc.gov/campaignproxyservice/subscriptions.aspx#featured)
[Contact Us](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#contactUs)
[Contact Us](https://www.cdc.gov/cdc-info/index.html)
- [Call 800-232-4636](tel:800-232-4636)
- [Contact CDC](https://www.cdc.gov/cdc-info/index.html)
[About CDC](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#aboutCDC)
[About CDC](https://www.cdc.gov/about/)
- [Pressroom](https://www.cdc.gov/media/)
- [Organization](https://www.cdc.gov/about/organization/)
- [Budget & Funding](https://www.cdc.gov/budget/)
- [Careers & Jobs](https://jobs.cdc.gov/index.html)
[Policies](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#policies)
- [Accessibility](https://www.cdc.gov/other/accessibility.html)
- [External Links](https://www.cdc.gov/Other/disclaimer.html#exit-notification)
- [Privacy](https://www.cdc.gov/other/privacy.html)
- [Web Policies](https://www.cdc.gov/Other/policies.html)
- [FOIA](https://www.cdc.gov/foia/)
- [OIG](https://oig.hhs.gov/)
- [No Fear Act](https://www.cdc.gov/oeeowe/no-fear-act/)
- [Nondiscrimination](https://www.cdc.gov/other/nondiscrimination.html)
- [Vulnerability Disclosure Policy](https://www.hhs.gov/vulnerability-disclosure-policy/index.html)
[Languages](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#languages)
[Languages](https://www.cdc.gov/other/other-languages/index.html)
- [Español](https://www.cdc.gov/spanish/)
[Language Assistance](https://www.cdc.gov/other/language-assistance.html)
- [Español](https://www.cdc.gov/other/language-assistance.html#Spanish)
- [繁體中文](https://www.cdc.gov/other/language-assistance.html#Chinese)
- [Tiếng Việt](https://www.cdc.gov/other/language-assistance.html#Vietnamese)
- [한국어](https://www.cdc.gov/other/language-assistance.html#Korean)
- [Tagalog](https://www.cdc.gov/other/language-assistance.html#Tagalog)
- [Русский](https://www.cdc.gov/other/language-assistance.html#Russian)
- [العربية](https://www.cdc.gov/other/language-assistance.html#Arabic)
- [Kreyòl Ayisyen](https://www.cdc.gov/other/language-assistance.html#Haitian)
- [Français](https://www.cdc.gov/other/language-assistance.html#French)
- [Polski](https://www.cdc.gov/other/language-assistance.html#Polish)
- [Português](https://www.cdc.gov/other/language-assistance.html#Portuguese)
- [Italiano](https://www.cdc.gov/other/language-assistance.html#Italian)
- [Deutsch](https://www.cdc.gov/other/language-assistance.html#German)
- [日本語](https://www.cdc.gov/other/language-assistance.html#Japanese)
- [فارسی](https://www.cdc.gov/other/language-assistance.html#Farsi)
- [English](https://www.cdc.gov/other/language-assistance.html#English)
[Archive](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#archive)
- [CDC Archive](https://archive.cdc.gov/)
- [Public Health Publications](https://stacks.cdc.gov/)
[Contact Us](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#mobile-footer-contactUs)
[Contact Us](https://www.cdc.gov/cdc-info/index.html)
- [Call 800-232-4636](tel:800-232-4636)
- [Contact CDC](https://www.cdc.gov/cdc-info/index.html)
[About CDC](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#mobile-footer-aboutCDC)
- [Pressroom](https://www.cdc.gov/media/)
- [Organization](https://www.cdc.gov/about/organization/)
- [Budget & Funding](https://www.cdc.gov/budget/)
- [Careers & Jobs](https://jobs.cdc.gov/index.html)
- [About CDC](https://www.cdc.gov/about/)
[Policies](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#mobile-footer-policies)
- [Accessibility](https://www.cdc.gov/other/accessibility.html)
- [External Links](https://www.cdc.gov/Other/disclaimer.html#exit-notification)
- [Privacy](https://www.cdc.gov/other/privacy.html)
- [Web Policies](https://www.cdc.gov/Other/policies.html)
- [FOIA](https://www.cdc.gov/foia/)
- [OIG](https://oig.hhs.gov/)
- [No Fear Act](https://www.cdc.gov/oeeowe/no-fear-act/)
- [Nondiscrimination](https://www.cdc.gov/other/nondiscrimination.html)
- [Vulnerability Disclosure Policy](https://www.hhs.gov/vulnerability-disclosure-policy/index.html)
[Languages](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#mobile-footer-languages)
Languages
- [Español](https://www.cdc.gov/spanish/)
Language Assistance
- [Español](https://www.cdc.gov/other/language-assistance.html#Spanish)
- [繁體中文](https://www.cdc.gov/other/language-assistance.html#Chinese)
- [Tiếng Việt](https://www.cdc.gov/other/language-assistance.html#Vietnamese)
- [한국어](https://www.cdc.gov/other/language-assistance.html#Korean)
- [Tagalog](https://www.cdc.gov/other/language-assistance.html#Tagalog)
- [Русский](https://www.cdc.gov/other/language-assistance.html#Russian)
- [العربية](https://www.cdc.gov/other/language-assistance.html#Arabic)
- [Kreyòl Ayisyen](https://www.cdc.gov/other/language-assistance.html#Haitian)
- [Français](https://www.cdc.gov/other/language-assistance.html#French)
- [Polski](https://www.cdc.gov/other/language-assistance.html#Polish)
- [Português](https://www.cdc.gov/other/language-assistance.html#Portuguese)
- [Italiano](https://www.cdc.gov/other/language-assistance.html#Italian)
- [Deutsch](https://www.cdc.gov/other/language-assistance.html#German)
- [日本語](https://www.cdc.gov/other/language-assistance.html#Japanese)
- [فارسی](https://www.cdc.gov/other/language-assistance.html#Farsi)
- [English](https://www.cdc.gov/other/language-assistance.html#English)
[Archive](https://www.cdc.gov/me-cfs/signs-symptoms/index.html#mobile-footer-archive)
- [CDC Archive](https://archive.cdc.gov/)
- [Public Health Publications](https://stacks.cdc.gov/)
[](https://www.cdc.gov/)
[HHS.gov](https://hhs.gov/) [USA.gov](https://usa.gov/) |
| Readable Markdown | - Myalgic encephalomyelitis/chronic fatigue syndrome symptoms are common in many other illnesses.
- There is no test to confirm ME/CFS. This makes it hard to diagnose.
- Symptoms are unpredictable and may change or come and go over time.
- However, a combination of core symptoms are used to diagnose ME/CFS.

## Primary symptoms
ME/CFS has five core symptoms. You must have three main ME/CFS symptoms and at least one of the other two symptoms to be diagnosed with ME/CFS.
### Less ability to do activities and fatigue (required)
People with ME/CFS have a much lower ability to do activities they could do before they got sick. This limitation comes with fatigue and lasts six months or longer.
The fatigue:
- Can be severe
- Isn't caused by an unusually difficult activity
- Isn't relieved by sleep or rest
### Worse symptoms after activity (required)
People with ME/CFS experience a worsening of their symptoms after any type of activity - physical or mental. These activities wouldn't have been a problem before they became ill. This is called Post-Exertional Malaise (PEM).
PEM can lead to a cycle of "pushing" to do more, followed by "crashing." During a crash, people with ME/CFS may have a variety of symptoms. These can include difficulty thinking, problems sleeping, sore throat, headaches, feeling dizzy, or severe tiredness.
It may take days, weeks, or longer to recover from a crash. Some people may be confined to bed or the house. As examples:
- Attending a school event may leave someone house-bound for days.
- Grocery shopping may require a nap in the car before driving home.
- Doing errands may require getting a ride home.
- Showering may leave someone bed-bound for days.
- Working may mean spending nights and weekends recovering.
### Sleep Problems (Required)
People with ME/CFS may not feel better or less tired, even after a full night's sleep. Some may have problems falling asleep or staying asleep.
## Additional symptoms (At least 1 required)
In addition to the three required symptoms above, one of the following two symptoms is needed to be diagnosed with ME/CFS.
### Memory and thinking problems
Most people with ME/CFS have trouble thinking quickly, remembering things, and paying attention to details. People with ME/CFS often say they have “brain fog” to describe this problem. This is because they feel “stuck in a fog” and not able to think clearly.
### Problems being upright
People with ME/CFS often report their symptoms get worse when they are standing or sitting upright. This is called orthostatic intolerance.
People with ME/CFS may be lightheaded, dizzy, weak, or faint while standing or sitting up. They may have vision changes like blurring or seeing spots.
## Other common symptoms
Many but not all people with ME/CFS have other symptoms.
**Pain** is very common in people with ME/CFS. The type of pain, where it occurs, and how bad it is varies a lot. The pain people with ME/CFS feel is not caused by an injury. The most common types of pain in ME/CFS are:
- Muscle pain and aches
- Joint pain without swelling or redness
- Headaches, either new or worsening
Some people with ME/CFS may also have:
- Tender lymph nodes in the neck or armpits
- Frequent sore throat
- Digestive issues, like irritable bowel syndrome
- Chills and night sweats
- Allergies or sensitivities to foods, odors, chemicals, light and noise
- Muscle weakness
- Shortness of breath
- Irregular heartbeat
May 10, 2024
Sources
- Disclaimer: This website is for informational purposes only. The information provided on this website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. |
| Shard | 5 (laksa) |
| Root Hash | 17308952984333333205 |
| Unparsed URL | gov,cdc!www,/me-cfs/signs-symptoms/index.html s443 |