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| Boilerpipe Text | Erythema migrans rash is a common symptom that occurs in over 70 percent of people with Lyme disease. Erythema migrans rashes have certain characteristics that help differentiate them from other types of skin lesions. Review the images below to learn what erythema migrans rashes look like versus other skin conditions.
Erythema migrans rashes
“Bull's-eye” or target lesion
Circular, expanding rash with target-like appearance.
Expanding rash with central crust
Expanding lesion with central crust on chest. Photo credit: Bernard Cohen
Expanding erythema migrans
Early, expanding erythema migrans with nodule. Photo credit: Reprinted from Bhate C, Schwartz RA. Lyme disease: Part I. Advances and perspectives.
J Am Acad Dermatol
2011;64:619-36, with permission from Elsevier.
Multiple rashes, disseminated infection
Early disseminated Lyme disease; multiple lesions with dusky centers. Photo credit: Bernard Cohen
Red, oval plaque
Red, expanding oval-shaped plaque on trunk. Photo credit: Alison Young
Expanding rash with central clearing
Circular, expanding rash with central clearing. Photo credit: Taryn Holman
Bluish hued rash, no central clearing
Bluish hued without central clearing. Photo credit: Yevgeniy Balagula
Expanding lesion, no central clearing
Expanding lesion without central clearing on back of knee. Photo credit: Gary Wormser
Red blue lesion with central clearing
Red-blue lesion with some central clearing on back of knee. Photo credit: Robin Stevenson
Skin conditions that are NOT erythema migrans
Insect bite hyper-sensitivity
Large itchy rash caused by an allergic reaction to an insect bite. Photo Credit: Chris Ha
Fixed drug reaction
A skin condition that occurs up to two weeks after a person takes a medication. The condition reappears at the same location everytime a person takes that particular medication. Photo credit: Shahbaz A. Janjua
Ringworm (tinea corporis)
Ringworm is a common skin infection that is caused by a fungus. It's called "ringworm" because it can cause a ring-shaped rash that is usually red and itchy with raised edges. Photo credit: Bernard Cohen
Pityriasis rosea rash
A rash without a known cause that can be a round or oval, pink, and scaly with a raised border. It can sometimes itch. Larger patches than the one shown here are also common. Photo credit: Bernard Cohen
Granuloma annulare rash
Reddish bumps on the skin arranged in a circle or ring. Photo credit: Bernard Cohen
Urticaria multiforme
Also known as hives. Often caused by an allergic reaction to food, an infection, or a medicine. May burn or itch. Photo credit: Bernard Cohen
May 15, 2024 |
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May 15, 2024
For Everyone
# Lyme Disease Rashes
## Key points
Erythema migrans rash is a common symptom that occurs in over 70 percent of people with Lyme disease. Erythema migrans rashes have certain characteristics that help differentiate them from other types of skin lesions. Review the images below to learn what erythema migrans rashes look like versus other skin conditions.

## Erythema migrans rashes
### Resources
[The Many Forms of Lyme Disease Rashes (Erythema Migrans) \[PDF – 1 page\]](https://www.cdc.gov/lyme/resources/NCEZID_rash_poster3r1-508.pdf)
[Signs and Symptoms of Lyme Disease - Social Media Graphic](https://www.cdc.gov/lyme/media/images/2024/06/348680-A-TickBitePrevention_Edits_2.jpg)
### “Bull's-eye” or target lesion

Circular, expanding rash with target-like appearance.
### Expanding rash with central crust

Expanding lesion with central crust on chest. Photo credit: Bernard Cohen
### Expanding erythema migrans

Early, expanding erythema migrans with nodule. Photo credit: Reprinted from Bhate C, Schwartz RA. Lyme disease: Part I. Advances and perspectives. *J Am Acad Dermatol* 2011;64:619-36, with permission from Elsevier.
### Multiple rashes, disseminated infection

Early disseminated Lyme disease; multiple lesions with dusky centers. Photo credit: Bernard Cohen
### Red, oval plaque

Red, expanding oval-shaped plaque on trunk. Photo credit: Alison Young
### Expanding rash with central clearing

Circular, expanding rash with central clearing. Photo credit: Taryn Holman
### Bluish hued rash, no central clearing

Bluish hued without central clearing. Photo credit: Yevgeniy Balagula
### Expanding lesion, no central clearing

Expanding lesion without central clearing on back of knee. Photo credit: Gary Wormser
### Red blue lesion with central clearing

Red-blue lesion with some central clearing on back of knee. Photo credit: Robin Stevenson
## Skin conditions that are NOT erythema migrans
### Insect bite hyper-sensitivity

Large itchy rash caused by an allergic reaction to an insect bite. Photo Credit: Chris Ha
### Fixed drug reaction

A skin condition that occurs up to two weeks after a person takes a medication. The condition reappears at the same location everytime a person takes that particular medication. Photo credit: Shahbaz A. Janjua
### Ringworm (tinea corporis)

Ringworm is a common skin infection that is caused by a fungus. It's called "ringworm" because it can cause a ring-shaped rash that is usually red and itchy with raised edges. Photo credit: Bernard Cohen
### Pityriasis rosea rash

A rash without a known cause that can be a round or oval, pink, and scaly with a raised border. It can sometimes itch. Larger patches than the one shown here are also common. Photo credit: Bernard Cohen
### Granuloma annulare rash

Reddish bumps on the skin arranged in a circle or ring. Photo credit: Bernard Cohen
### Urticaria multiforme

Also known as hives. Often caused by an allergic reaction to food, an infection, or a medicine. May burn or itch. Photo credit: Bernard Cohen
## Related Pages
- [Signs and Symptoms](https://www.cdc.gov/lyme/signs-symptoms/index.html)
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[View All Lyme Disease](https://www.cdc.gov/lyme/site.html#gen)
[Chronic symptoms and Lyme disease](https://www.cdc.gov/lyme/signs-symptoms/chronic-symptoms-and-lyme-disease.html)
May 15, 2024
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| Readable Markdown | Erythema migrans rash is a common symptom that occurs in over 70 percent of people with Lyme disease. Erythema migrans rashes have certain characteristics that help differentiate them from other types of skin lesions. Review the images below to learn what erythema migrans rashes look like versus other skin conditions.

## Erythema migrans rashes
### “Bull's-eye” or target lesion

Circular, expanding rash with target-like appearance.
### Expanding rash with central crust

Expanding lesion with central crust on chest. Photo credit: Bernard Cohen
### Expanding erythema migrans

Early, expanding erythema migrans with nodule. Photo credit: Reprinted from Bhate C, Schwartz RA. Lyme disease: Part I. Advances and perspectives. *J Am Acad Dermatol* 2011;64:619-36, with permission from Elsevier.
### Multiple rashes, disseminated infection

Early disseminated Lyme disease; multiple lesions with dusky centers. Photo credit: Bernard Cohen
### Red, oval plaque

Red, expanding oval-shaped plaque on trunk. Photo credit: Alison Young
### Expanding rash with central clearing

Circular, expanding rash with central clearing. Photo credit: Taryn Holman
### Bluish hued rash, no central clearing

Bluish hued without central clearing. Photo credit: Yevgeniy Balagula
### Expanding lesion, no central clearing

Expanding lesion without central clearing on back of knee. Photo credit: Gary Wormser
### Red blue lesion with central clearing

Red-blue lesion with some central clearing on back of knee. Photo credit: Robin Stevenson
## Skin conditions that are NOT erythema migrans
### Insect bite hyper-sensitivity

Large itchy rash caused by an allergic reaction to an insect bite. Photo Credit: Chris Ha
### Fixed drug reaction

A skin condition that occurs up to two weeks after a person takes a medication. The condition reappears at the same location everytime a person takes that particular medication. Photo credit: Shahbaz A. Janjua
### Ringworm (tinea corporis)

Ringworm is a common skin infection that is caused by a fungus. It's called "ringworm" because it can cause a ring-shaped rash that is usually red and itchy with raised edges. Photo credit: Bernard Cohen
### Pityriasis rosea rash

A rash without a known cause that can be a round or oval, pink, and scaly with a raised border. It can sometimes itch. Larger patches than the one shown here are also common. Photo credit: Bernard Cohen
### Granuloma annulare rash

Reddish bumps on the skin arranged in a circle or ring. Photo credit: Bernard Cohen
### Urticaria multiforme

Also known as hives. Often caused by an allergic reaction to food, an infection, or a medicine. May burn or itch. Photo credit: Bernard Cohen
May 15, 2024 |
| Shard | 5 (laksa) |
| Root Hash | 17308952984333333205 |
| Unparsed URL | gov,cdc!www,/lyme/signs-symptoms/lyme-disease-rashes.html s443 |