šŸ•·ļø Crawler Inspector

URL Lookup

Direct Parameter Lookup

Raw Queries and Responses

1. Shard Calculation

Query:
Response:
Calculated Shard: 148 (from laksa146)

2. Crawled Status Check

Query:
Response:

3. Robots.txt Check

Query:
Response:

4. Spam/Ban Check

Query:
Response:

5. Seen Status Check

ā„¹ļø Skipped - page is already crawled

šŸ“„
INDEXABLE
āœ…
CRAWLED
1 day ago
šŸ¤–
ROBOTS ALLOWED

Page Info Filters

FilterStatusConditionDetails
HTTP statusPASSdownload_http_code = 200HTTP 200
Age cutoffPASSdownload_stamp > now() - 6 MONTH0 months ago
History dropPASSisNull(history_drop_reason)No drop reason
Spam/banPASSfh_dont_index != 1 AND ml_spam_score = 0ml_spam_score=0
CanonicalPASSmeta_canonical IS NULL OR = '' OR = src_unparsedNot set

Page Details

PropertyValue
URLhttps://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection
Last Crawled2026-04-14 00:05:48 (1 day ago)
First Indexed2020-07-25 13:18:38 (5 years ago)
HTTP Status Code200
Meta TitleCan you catch the coronavirus twice? Here's what research says.
Meta DescriptionRecent media reports have claimed that some recovered Covid-19 patients have been reinfected with the coronavirus, sparking doubts about whether people can ever gain lasting immunity against the virus. But what does the evidence say?
Meta Canonicalnull
Boilerpipe Text
Sporadic reports of Covid-19 patients seeminglyĀ becoming reinfected with the coronavirus have sparked doubts about whether people can ever gain immunity against the pathogen—and although current research suggests reinfection within a short time frame is unlikely, some researchers are hesitant to completely dismiss the idea. Your top resources for Covid-19 response and resilience Doctors' stories, new studies raise concerns about coronavirus immunity Since the coronavirus pandemic began, there have been reports from doctors throughout the world about recovered Covid-19 patients seemingly becoming reinfected with the novel coronavirus, leaving some people doubting whether humans can become immune to the virus. For instance, a physician in New Jersey has claimed that at least two of his Covid-19 patients had recovered from and tested negative for the coronavirus for months, but then started again experiencing symptoms of the disease and tested positive. One of those patients began showing symptoms of Covid-19 again after attending a party. "So that is … reinfection," the doctor said. The physician said the second recovered patient who appeared to be reinfected was a family member of the first patient. According to the doctor, that patient had tested negative for the coronavirus for several weeks, and even had developed enough antibodies to the virus that he was able to donate plasma for experimental Covid-19 treatments before again experiencing symptoms of the disease. Further, some recent studies also have sparked questions about coronavirus immunity. For example, results from a study recently released in preprint that hasn't yet been peer reviewed showed that antibodies developed against the coronavirus in people who'd been infected declined significantly within two to three months post infection. Moreover, Elitza Theel, director of the infectious diseases serology laboratory at the Mayo Clinic who was not involved in the study, said researchers are finding that coronavirus "antibodies will peak at about 20 to 30 days after symptom onset, and then they decline," and "[t]hey seem to decline much more rapidly in individuals that were asymptomatic or had mild forms of the disease." Given that antibodies help to neutralize the coronavirus and are believed to provide people with immunity against the pathogen, those findings have raised alarms among some observers that people may gain natural immunity to the coronavirus for only a few months. Robert Glatter, an assistant professor of emergency medicine at Lenox Hill Hospital and Northwell Health , explained that, if people could become reinfected with the coronavirus within a short period of time, it would mean that people may need to receive multiple vaccinations against the virus throughout the year to control the coronavirus' spread. "It would definitely be a predicament for public health, there's no question about that," especially if there isn't a vaccine against the virus, said Kamran Kadkhoda, medical director of immunopathology at the Cleveland Clinic . "In the absence of a vaccine, the main thing that we'd have against reinfection are these prevention measures" such as physical distancing and face masks, Kadkhoda explained. Research suggests coronavirus reinfection is unlikely But despite the anecdotal reports from doctors about patients becoming reinfected with the coronavirus, researchers say there's no evidence supporting the notion that people can become reinfected with the virus within a short time period. "I haven't heard of a case where it's been truly unambiguously demonstrated," said Marc Lipsitch, an epidemiologist at the Harvard T.H. Chan School of Public Health . For instance, South Korea's Center for Disease Control and Prevention in one study confirmed that, among 285 cases of people who again tested positive for the coronavirus two months after receiving their initial positive test results (including some who were experiencing Covid-19 symptoms two months after their initial diagnoses), none of the patients' new samples contained enough virus particles to allow researchers to grow the virus from the samples in a lab. Researchers said those results indicated that the patients weren't actively infected with the virus, and the diagnostic tests likely had detected dead virus particles that remained in their bodies or generated false-positive positive results. Further, the researchers noted that none of the patients who re-tested positive for the coronavirus transmitted the pathogen to others. "It was pretty solid epidemiological and virological evidence that reinfection was not happening, at least in those people," Angela Rasmussen, a virologist at Columbia University , said. As for studies showing that antibodies for the novel coronavirus decline over time, researchers say that's how antibodies work for a host of viruses. Michael Mina, an immunologist at Harvard University , said although those studies have left some people "scratching their heads saying, 'What an extraordinarily odd virus that it's not leading to robust immunity,' … they're totally wrong." "It doesn't get more textbook than this," he added. And some research has resulted in different findings regarding coronavirus antibody levels over time. For example, results from a separate study that were released preprint and haven't been peer reviewed found that 120 patients who were infected with the coronavirus and experienced mild or moderate symptoms of Covid-19 had stable levels of coronavirus antibodies for at least three months post infection—and in some cases, those levels increased over that time. In addition, even if someone who had been infected with the coronavirus didn't develop antibodies for the pathogen, a person's T-cells and B-cells could fight off reinfection, public health experts say. "Even if you don't have a very high level of antibodies, you may be able to respond very rapidly to a challenge and nip it in the bud," said Michel Nussenzweig, head of the laboratory for molecular immunology at Rockefeller University . "You may be able to produce a better … faster response the second time around." Ultimately, Monica Gandhi, a professor of medicine and associate chief of infectious diseases at the University of California-San Francisco , said, "No one is yet believing in reinfection since there is no good scientific report on it." So why do some people experience Covid-19 symptoms twice? So why, then, do some people seemingly recover from Covid-19 but again experience symptoms later? Clinicians say more research is needed to answer the question of why some patients appear to fall ill with Covid-19 more than once, but some believe that such patients simply relapse because the coronavirus lays dormant in their bodies and reemerges—an occurrence that's been seen with some viruses that often result in lifetime immunity, such as the chickenpox virus, according to Daniel Griffin, an infectious diseases doctor and researcher at Columbia University Medical Center . It also may be possible that some patients experience a long course of infection that ramps up months after they first contract the coronavirus and initially experience symptoms of Covid-19, some experts have said. And others have speculated that some patients may contract a different virus with similar symptoms to Covid-19 and assume they've been reinfected with the coronavirus. But 'no one wants to dismiss the possibility' of reinfection completely However, while most experts say they don't think it's likely people can contract the coronavirus more than once within a short period of time, "no one wants to dismiss the possibility" of reinfection altogether, Gandhi said. And Griffin noted that, if researchers eventually find two different versions of the novel coronavirus' genetic code in one patient's body, it could point to two separate infections. "This is one of those things I really don't want to be true," Griffin said, "[b]ut a lot of us are starting to say, 'I'm willing to entertain it as a possibility. Let's keep our eyes out and start watching'" (Johnson/Cha, Washington Post , 7/22; Resnick/Irfan, Vox , 7/22; Mandavilli, New York Times , 7/22; Craig, Monmouth Daily Voice , 7/9; Sternlicht, Forbes , 5/19).
Markdown
# Your Choice Regarding Extending Session on this Site You may be receiving this error message if you are logged out. Be sure to log into your account to access the resources. Auto logout in seconds. [Continue](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) [Logout](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) ### Today's Updates - Report [12 things CEOs need to know in 2026](https://www.advisory.com/topics/state-of-healthcare-industry/ceo-briefing-2026 "12 things CEOs need to know in 2026") - Podcast [Ep. 293: The state of AMCs in 2026, and what leaders should watch next](https://www.advisory.com/radio-advisory/293 "Ep. 293: The state of AMCs in 2026, and what leaders should watch next") - Daily Briefing [Join 165,000+ healthcare leaders and get the industry’s most important news in your inbox—every day.](https://www.advisory.com/memberships/subscribe-public-daily-briefing "Subscribe to the Daily Briefing") Previous news Next news [![Advisory Board](https://www.advisory.com/content/experience-fragments/advisory/us/en/site/header/master/_jcr_content/root/header/image.coreimg.svg/1678950063715/ab-header-logo.svg)](https://www.advisory.com/home) ![]() - [Account Settings](https://www.advisory.com/account-info/account-settings) - [Logout](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) [Sign In](https://www.advisory.com/account-info/login) [Create Account](https://www.advisory.com/account-info/create-account) [Become a Member](https://www.advisory.com/company/products/digital-subscription) [Manage Account](https://www.advisory.com/account-info/account-settings) [Logout](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) [Manage Account](https://www.advisory.com/account-info/account-settings) [Logout](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) [Become a Member](https://www.advisory.com/company/products/digital-subscription) - # FEATURED INSIGHTS - [Nursing](https://www.advisory.com/featured/nursing) - [Post-election coverage](https://www.advisory.com/healthcare-policy-updates) - [Provider operations](https://www.advisory.com/featured/provider-operations) - [Site-of-care shifts](https://www.advisory.com/featured/site-of-care-shifts) - [Specialty care](https://www.advisory.com/featured/specialty-care) - [State of the healthcare industry](https://www.advisory.com/featured/state-of-the-healthcare-industry) - [Value-based care](https://www.advisory.com/featured/value-based-care) - [View all featured insights](https://www.advisory.com/featured) - # RESOURCES BY SECTOR - [Digital health](https://www.advisory.com/sectors/digital-health) - [Health plans](https://www.advisory.com/sectors/health-plans) - [Hospitals and health systems](https://www.advisory.com/sectors/hospitals-and-health-systems) - [Medical device](https://www.advisory.com/sectors/medical-device) - [Physicians and medical groups](https://www.advisory.com/sectors/physicians-and-medical-groups) - [Professional services](https://www.advisory.com/sectors/purchased-and-professional-services) - [View all sectors](https://www.advisory.com/sectors) - # NEWS & INSIGHTS - [Daily Briefing](https://www.advisory.com/daily-briefing/2026/04/09) - [Radio Advisory](https://www.advisory.com/radio-advisory) - [Advisory Board tools](https://www.advisory.com/tools-and-analytics) - # PRODUCTS & SERVICES - [Research Membership](https://www.advisory.com/company/products/research-membership) - [Custom Research](https://www.advisory.com/company/products/custom-research) - [Events](https://www.advisory.com/company/products/advisory-board-events) - [Expert Support](https://www.advisory.com/company/products/expert-support) - [Advisory Board Fellowship](https://www.advisory.com/company/products/advisory-board-fellowship) - [On-Demand Courses](https://www.advisory.com/company/products/advisory-board-on-demand-courses) - [Sponsorship](https://www.advisory.com/company/products/sponsorship) - ##### FEATURED CONTENT [Expert Insight Site-of-care shifts: Healthcare’s \$50B opportunity Understand the current state of outpatient shift, how it's likely to change your market, and how to use it for growth.](https://www.advisory.com/topics/strategy-planning-and-growth/2024/07/soc-shifts-50b-opportunity) [AskAdvisory Our direct-to-expert service is here to help you navigate your membership, our research, and your most pressing challenges in healthcare. No question is too big or too small. July 24, 2020](https://ask.advisory.com/) - Our Research - ### Care Delivery - [Ambulatory care](https://www.advisory.com/topics/ambulatory-care) - [Behavioral health](https://www.advisory.com/topics/behavioral-health) - [Cardiovascular](https://www.advisory.com/topics/cardiovascular) - [Oncology](https://www.advisory.com/topics/oncology) - [Pharmacy](https://www.advisory.com/topics/pharmacy) - [Population health](https://www.advisory.com/topics/population-health) - [Post-acute care](https://www.advisory.com/topics/post-acute-care) - [Service lines and specialty care](https://www.advisory.com/topics/service-lines-specialty-care) - [Weight management and obesity care](https://www.advisory.com/topics/weight-management-obesity-care) - [Women's health](https://www.advisory.com/topics/womens) [Learn more](https://www.advisory.com/research) ### Strategy - [Consumer trends](https://www.advisory.com/topics/consumer-trends) - [Finance](https://www.advisory.com/topics/finance) - [Health plan strategy](https://www.advisory.com/topics/health-plan-strategy) - [Healthcare policy updates](https://www.advisory.com/healthcare-policy-updates) - [Hospital and health system trends](https://www.advisory.com/topics/hospital-health-system-trends) - [International](https://www.advisory.com/topics/international) - [Market trends and growth strategy](https://www.advisory.com/topics/market-trends) - [Site-of-care shifts](https://www.advisory.com/topics/site-of-care-shifts) - [State of the healthcare industry](https://www.advisory.com/topics/state-of-healthcare-industry) - [Value-based care](https://www.advisory.com/topics/value-based-care) ### Staffing & Operations - [Facility planning](https://www.advisory.com/topics/facility-planning-trends) - [Leadership](https://www.advisory.com/topics/leadership) - [Nursing](https://www.advisory.com/topics/nursing) - [Philanthropy](https://www.advisory.com/topics/philanthropy) - [Physicians and medical groups](https://www.advisory.com/topics/physicians-medical-groups) - [Provider operations](https://www.advisory.com/topics/provider-operations) - [Sales enablement](https://www.advisory.com/topics/sales-enablement) - [Workforce](https://www.advisory.com/topics/workforce) ### Technology & Innovation - [Artificial intelligence](https://www.advisory.com/topics/artificial-intelligence) - [Digital access and experience](https://www.advisory.com/topics/digital-access-experience) - [Digital health](https://www.advisory.com/topics/digital-health) - [Medical device](https://www.advisory.com/topics/medical-device) - [Pharmaceutical](https://www.advisory.com/topics/pharmaceutical) - [Telehealth](https://www.advisory.com/topics/telehealth) **LATEST RESEARCH** [![](https://www.advisory.com/content/experience-fragments/advisory/us/en/site/header/master/_jcr_content/root/header/subnav/container0/container/icontext.coreimg.jpeg/1775483038080/woman-working-at-desk-office.jpeg) ![]() How AI rewired prior authorization at Renown Health](https://www.advisory.com/topics/artificial-intelligence/ai-rewired-prior-authorization) [![](https://www.advisory.com/content/experience-fragments/advisory/us/en/site/header/master/_jcr_content/root/header/subnav/container0/container/icontext_590813280.coreimg.jpeg/1775483067595/female-patient-in-hospital-with-female-doctor.jpeg) ![]() Updating COVID-19 management protocols may help address long-term impacts](https://www.advisory.com/sponsored/updating-covid-management-protocols) [![](https://www.advisory.com/content/experience-fragments/advisory/us/en/site/header/master/_jcr_content/root/header/subnav/container0/container/icontext_1178914492.coreimg.jpeg/1775483090885/women-leading-the-way-in-healthcare.jpeg) ![]() The hidden cost of denials: How process failures erode provider trust](https://www.advisory.com/topics/health-plan-provider-collaboration/hidden-cost-of-denials) [More recent research](https://www.advisory.com/latest-research) **STAY IN THE KNOW** **Daily Briefing** [A must-read daily newsletter for thousands of healthcare executives across the nation.](https://www.advisory.com/daily-briefing "daily briefing") **Radio Advisory** [A podcast providing your weekly download on how to untangle healthcare's most pressing challenges. New episodes drop every Tuesday.](https://www.advisory.com/radio-advisory "radio advisory") - Tools - ### FORECASTING & DEMAND - [Market Scenario Planner](https://www.advisory.com/topics/market-analytics-and-forecasting/2019/05/market-scenario-planner) - [Demographic Profiler](https://www.advisory.com/topics/market-analytics-and-forecasting/2016/07/demographics-profiler) - [Clinician Supply Profiler](https://www.advisory.com/topics/market-analytics-and-forecasting/2015/06/physician-demand-estimator) - [Cancer Incidence Estimator](https://www.advisory.com/topics/oncology/2020/06/cancer-incidence-estimator) ### COMPETITION & MARKET SHARE - [Medicare Market Explorer](https://www.advisory.com/topics/medicare/2017/06/medicare-market-share-tool) - [Health Care Facility Quickview Map](https://www.advisory.com/topics/facility-planning/2021/04/health-care-facility-quickview-map) - [Health Plan Market Explorer](https://www.advisory.com/topics/health-plan/health-plan-market-explorer) ### PERFORMANCE IMPROVEMENT & BENCHMARKING - [Care Variation Reduction Assessment](https://www.advisory.com/topics/care-variation-reduction/care-variation-reduction-assessment) - [Hospital Benchmark Generator](https://www.advisory.com/topics/market-analytics-and-forecasting/2018/09/benchmark-generator) - [Hospital Performance Profiler](https://www.advisory.com/topics/margin-management/2015/05/hospital-performance-profiler) ### POST-ACUTE CARE & NETWORK DESIGN - [Post-Acute Care Pathways Explorer](https://www.advisory.com/topics/health-plan/2017/04/the-post-acute-pathways-explorer) - [Home Health Performance Profiler](https://www.advisory.com/topics/post-acute-care/2017/08/home-health-performance-profiler) - [Home Health Benchmark Generator](https://www.advisory.com/topics/post-acute-care/2017/08/home-health-benchmark-generator) - [Skilled Nursing Facility Benchmark Generator](https://www.advisory.com/topics/post-acute-care/2014/10/snf-benchmark-generator) - [Skilled Nursing Facility Performance Profiler](https://www.advisory.com/topics/post-acute-care/2016/02/the-skilled-nursing-facility-performance-profiler) [See all tools](https://www.advisory.com/tools-and-analytics "see all tools") - Events & Webinars - Products & Services - [![](https://www.advisory.com/content/experience-fragments/advisory/us/en/site/header/master/_jcr_content/root/header/subnav/container3/static_card.coreimg.png/1730314389485/research-membership.png) ![]() Research Membership Access to insights, resources, and tools designed to address the healthcare industry's most pressing challenges. Research & Insights Data & Analytical Planning Tools Webinars Expert Conversations](https://www.advisory.com/company/products/research-membership) [![](https://www.advisory.com/content/experience-fragments/advisory/us/en/site/header/master/_jcr_content/root/header/subnav/container3/static_card_49307815.coreimg.jpeg/1730177295055/ask-advisory-web-graphics-02-440.jpeg) ![]() ASKADVISORY Our direct-to-expert service is here to help you navigate your membership, our research, and your most pressing challenges in healthcare. No question is too big or too small.](https://ask.advisory.com/) **Custom Research** [Original research into the topics you care about most, conducted the Advisory Board way.](https://www.advisory.com/company/products/custom-research) **Expert Support** [Connections to healthcare experts that help break through challenges and identify the most pressing opportunities.](https://www.advisory.com/company/products/expert-support) **Advisory Board Fellowship** [An immersive leadership practice ground, empowering leaders to make progress on organizational challenges.](https://www.advisory.com/company/products/advisory-board-fellowship) **Events & Roundtables** [In-person and virtual experiences designed to deliver crucial healthcare information and foster meaningful connections with peers and industry experts.](https://www.advisory.com/company/products/advisory-board-events "advisory board events") **Webinars** [Join our expert-led webinars to get the latest insights on topics such as the state of the industry, value-based care, health system strategy, specialty care market trends, and more.](https://www.advisory.com/webinars) **Sponsorship** [Thought leadership opportunities to elevate your brand, showcase your expertise, and engage with key decision-makers.](https://www.advisory.com/company/products/sponsorship) [See all Products & Services](https://www.advisory.com/company/products) - About Us - **ADVISORY BOARD** We help leaders and future leaders in the healthcare industry work smarter and faster by providing provocative insights, actionable strategies, and practical tools to support execution. [Learn more about us](https://www.advisory.com/about-us "about us") **Who We Serve** [We empower our members, and the entire healthcare industry, to confidently reimagine healthcare with breakthrough insights that open minds and inspire action.](https://www.advisory.com/who-we-serve "who we serve") **OUR HISTORY** [Advisory Board has changed a lot over its 40-year history, but what has not changed is our commitment to addressing tough questions with unbiased, disciplined research.](https://www.advisory.com/our-history "our history") **OUR EXPERTS** [Our team of 200+ curious researchers work full time to uncover the insights that you need to know and the solutions that will work.](https://www.advisory.com/expert-directory "expert directory") **CAREERS** [Join us to improve the lives of others while doing your life's best work.](https://www.advisory.com/careers "careers") Questions? [AskAdvisory](https://ask.advisory.com/ "Ask Advisory") Library \| Daily Briefing 5 minute read # Can you catch the coronavirus twice? Here's what research says. *** Sporadic reports of Covid-19 patients seemingly becoming reinfected with the coronavirus have sparked doubts about whether people can ever gain immunity against the pathogen—and although current research suggests reinfection within a short time frame is unlikely, some researchers are hesitant to completely dismiss the idea. [**Your top resources for Covid-19 response and resilience**](https://www.advisory.com/research/covid-19) ### Doctors' stories, new studies raise concerns about coronavirus immunity Since the coronavirus pandemic began, there have been reports from doctors throughout the world about recovered Covid-19 patients seemingly becoming reinfected with the novel coronavirus, leaving some people doubting whether humans can become immune to the virus. For instance, a physician in New Jersey has [claimed](https://www.youtube.com/watch?v=Qjh4WuV94VQ&feature=youtu.be) that at least two of his Covid-19 patients had recovered from and tested negative for the coronavirus for months, but then started again experiencing symptoms of the disease and tested positive. One of those patients began showing symptoms of Covid-19 again after attending a party. "So that is … reinfection," the doctor said. The physician said the second recovered patient who appeared to be reinfected was a family member of the first patient. According to the doctor, that patient had tested negative for the coronavirus for several weeks, and even had developed enough antibodies to the virus that he was able to donate plasma for experimental Covid-19 treatments before again experiencing symptoms of the disease. Further, some recent studies also have sparked questions about coronavirus immunity. For example, results from a [study](https://www.medrxiv.org/content/10.1101/2020.07.09.20148429v1) recently released in preprint that hasn't yet been peer reviewed showed that antibodies developed against the coronavirus in people who'd been infected declined significantly within two to three months post infection. Moreover, Elitza Theel, director of the infectious diseases serology laboratory at the **Mayo Clinic** who was not involved in the study, said researchers are finding that coronavirus "antibodies will peak at about 20 to 30 days after symptom onset, and then they decline," and "\[t\]hey seem to decline much more rapidly in individuals that were asymptomatic or had mild forms of the disease." Given that antibodies help to neutralize the coronavirus and are believed to provide people with immunity against the pathogen, those findings have raised alarms among some observers that people may gain natural immunity to the coronavirus for only a few months. Robert Glatter, an assistant professor of emergency medicine at **Lenox Hill Hospital** and **Northwell Health**, explained that, if people could become reinfected with the coronavirus within a short period of time, it would mean that people may need to receive multiple vaccinations against the virus throughout the year to control the coronavirus' spread. "It would definitely be a predicament for public health, there's no question about that," especially if there isn't a vaccine against the virus, said Kamran Kadkhoda, medical director of immunopathology at the **Cleveland Clinic**. "In the absence of a vaccine, the main thing that we'd have against reinfection are these prevention measures" such as physical distancing and face masks, Kadkhoda explained. ### Research suggests coronavirus reinfection is unlikely But despite the anecdotal reports from doctors about patients becoming reinfected with the coronavirus, researchers say there's no evidence supporting the notion that people can become reinfected with the virus within a short time period. "I haven't heard of a case where it's been truly unambiguously demonstrated," said Marc Lipsitch, an epidemiologist at the **Harvard T.H. Chan School of Public Health**. For instance, South Korea's **Center for Disease Control and Prevention** in one [study](https://www.cdc.go.kr/board/board.es?mid=a30402000000&bid=0030&act=view&list_no=367267) confirmed that, among 285 cases of people who again tested positive for the coronavirus two months after receiving their initial positive test results (including some who were experiencing Covid-19 symptoms two months after their initial diagnoses), none of the patients' new samples contained enough virus particles to allow researchers to grow the virus from the samples in a lab. Researchers said those results indicated that the patients weren't actively infected with the virus, and the diagnostic tests likely had detected dead virus particles that remained in their bodies or generated false-positive positive results. Further, the researchers noted that none of the patients who re-tested positive for the coronavirus transmitted the pathogen to others. "It was pretty solid epidemiological and virological evidence that reinfection was not happening, at least in those people," Angela Rasmussen, a virologist at **Columbia University**, said. As for studies showing that antibodies for the novel coronavirus decline over time, researchers say that's how antibodies work for a host of viruses. Michael Mina, an immunologist at **Harvard University**, said although those studies have left some people "scratching their heads saying, 'What an extraordinarily odd virus that it's not leading to robust immunity,' … they're totally wrong." "It doesn't get more textbook than this," he added. And some research has resulted in different findings regarding coronavirus antibody levels over time. For example, results from a separate [study](https://www.medrxiv.org/content/10.1101/2020.07.14.20151126v1.full.pdf) that were released preprint and haven't been peer reviewed found that 120 patients who were infected with the coronavirus and experienced mild or moderate symptoms of Covid-19 had stable levels of coronavirus antibodies for at least three months post infection—and in some cases, those levels increased over that time. In addition, even if someone who had been infected with the coronavirus didn't develop antibodies for the pathogen, a person's T-cells and B-cells could fight off reinfection, public health experts say. "Even if you don't have a very high level of antibodies, you may be able to respond very rapidly to a challenge and nip it in the bud," said Michel Nussenzweig, head of the laboratory for molecular immunology at **Rockefeller University**. "You may be able to produce a better … faster response the second time around." Ultimately, Monica Gandhi, a professor of medicine and associate chief of infectious diseases at the **University of California-San Francisco**, said, "No one is yet believing in reinfection since there is no good scientific report on it." **So why do some people experience Covid-19 symptoms twice?** So why, then, do some people seemingly recover from Covid-19 but again experience symptoms later? Clinicians say more research is needed to answer the question of why some patients appear to fall ill with Covid-19 more than once, but some believe that such patients simply relapse because the coronavirus lays dormant in their bodies and reemerges—an occurrence that's been seen with some viruses that often result in lifetime immunity, such as the chickenpox virus, according to Daniel Griffin, an infectious diseases doctor and researcher at **Columbia University Medical Center**. It also may be possible that some patients experience a long course of infection that ramps up months after they first contract the coronavirus and initially experience symptoms of Covid-19, some experts have said. And others have speculated that some patients may contract a different virus with similar symptoms to Covid-19 and assume they've been reinfected with the coronavirus. ### But 'no one wants to dismiss the possibility' of reinfection completely However, while most experts say they don't think it's likely people can contract the coronavirus more than once within a short period of time, "no one wants to dismiss the possibility" of reinfection altogether, Gandhi said. And Griffin noted that, if researchers eventually find two different versions of the novel coronavirus' genetic code in one patient's body, it could point to two separate infections. "This is one of those things I really don't want to be true," Griffin said, "\[b\]ut a lot of us are starting to say, 'I'm willing to entertain it as a possibility. Let's keep our eyes out and start watching'" (Johnson/Cha, [*Washington Post*](https://www.washingtonpost.com/health/2020/07/22/can-you-get-coronavirus-twice/?utm_source=rss&utm_medium=referral&utm_campaign=wp_health), 7/22; Resnick/Irfan, [*Vox*](https://www.vox.com/2020/7/22/21324729/getting-covid-19-twice-immunity-antibodies-vaccine-herd-immunity), 7/22; Mandavilli, [*New York Times*](https://www.nytimes.com/2020/07/22/health/covid-antibodies-herd-immunity.html?campaign_id=9&emc=edit_nn_20200723&instance_id=20544&nl=the-morning&regi_id=79817166&segment_id=34125&te=1&user_id=c57f9051ed41ab7de15bac33092fda41), 7/22; Craig, [Monmouth *Daily Voice*](https://dailyvoice.com/new-jersey/monmouth/news/central-jersey-doctor-reports-patients-reinfected-with-coronavirus/790555/), 7/9; Sternlicht, [*Forbes*](https://www.forbes.com/sites/alexandrasternlicht/2020/05/18/south-korea-says-patients-who-re-tested-positive-after-recovering-were-no-longer-infectious/#3167cd8b70a6), 5/19). ##### Is this content helpful? *** SPONSORED BY *** INTENDED AUDIENCE *** AFTER YOU READ THIS *** AUTHORS Posted on July 24, 2020 Updated on March 20, 2023 *** TOPICS *** INDUSTRY SECTORS *** MORE FROM TODAY'S DAILY BRIEFING [Daily Briefing Flu in the Southern Hemisphere has 'practically disappeared.' What does that mean for America's flu season? Many countries in the Southern Hemisphere are reporting far fewer flu cases than in previous years—and health officials are attributing the decline to restrictions put into place to control the new coronavirus. Here's what that could mean for America's upcoming flu season.](https://www.advisory.com/daily-briefing/2020/07/24/coronavirus-restrictions) [![Advisory Board](https://www.advisory.com/content/experience-fragments/advisory/us/en/site/footer/master/_jcr_content/root/footer/Image.coreimg.svg/1764943164292/footer-logo.svg)](https://www.advisory.com/home) ![]() We help leaders and future leaders in the healthcare industry work smarter and faster by providing provocative insights, actionable strategies, and practical tools to support execution. # Research & Events - [Latest research](https://www.advisory.com/latest-research) - [Daily Briefing](https://www.advisory.com/daily-briefing/2026/04/09) - [Radio Advisory](https://www.advisory.com/radio-advisory) - [Events](https://www.advisory.com/search#t=Latest&sort=relevancy&f:@abcontenttype=%5BMeeting,Webinar%5D) - [Search](https://www.advisory.com/search) # Company - [About us](https://www.advisory.com/about-us) - [Our history](https://www.advisory.com/our-history) - [Products](https://www.advisory.com/company/products) - [Sponsorship](https://www.advisory.com/company/products/sponsorship) - [Careers](https://www.advisory.com/careers) # Support - [AskAdvisory](https://ask.advisory.com/) - [Contact us](https://www.advisory.com/support/contact-us) # Social - [Facebook](https://www.facebook.com/pages/The-Advisory-Board-Company/181400411909303) - [Instagram](https://www.instagram.com/advisory_bd) - [LinkedIn](https://www.linkedin.com/company/the-advisory-board-company) # - [Legal Disclaimer](https://www.advisory.com/legal-disclaimer) - [Privacy Policy](https://www.advisory.com/privacy-policy) - [Terms of Use](https://www.advisory.com/terms-of-use) ## Don't miss out on the latest Advisory Board insights Create your free account to access 1 resource, including the latest research and webinars. [Create Account](https://www.advisory.com/account-info/create-account) [Sign in to your account](https://www.advisory.com/account-info/login) #### Want access without creating an account? [Get Limited Access](https://www.advisory.com/account-info/trial-access) You have 1 free members-only resource remaining this month. [View this resource](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) [1](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) free members-only resources remaining [Become a Member](https://www.advisory.com/company/products/digital-subscription) [1](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) free members-only resources remaining [Create Account](https://www.advisory.com/account-info/create-account) You've reached your limit of free insights ### Become a member to access all of Advisory Board's resources, events, and experts Never miss out on the latest innovative health care content tailored to you. [Become a Member](https://www.advisory.com/company/products/digital-subscription) #### Benefits include: Unlimited access to research and resources Member-only access to events and trainings Expert-led consultation and facilitation The latest content delivered to your inbox [Become a Member](https://www.advisory.com/company/products/digital-subscription) You've reached your limit of free insights ## Become a member to access all of Advisory Board's resources, events, and experts Never miss out on the latest innovative health care content tailored to you. [Create Account](https://www.advisory.com/account-info/create-account) [Become a Member](https://www.advisory.com/company/products/digital-subscription) #### Benefits include: Unlimited access to research and resources Member-only access to events and trainings Expert-led consultation and facilitation The latest content delivered to your inbox This content is available through your Curated Research partnership with Advisory Board. Click on ā€˜view this resource’ to read the full piece [View this resource](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) Email [ask@advisory.com](mailto:ask@advisory.com) to learn more ### Click on ā€˜Become a Member’ to learn about the benefits of a Full-Access partnership with Advisory Board Never miss out on the latest innovative health care content tailored to you. [Become a Member](https://www.advisory.com/company/products/digital-subscription) #### Benefits Include: Unlimited access to research and resources Member-only access to events and trainings Expert-led consultation and facilitation The latest content delivered to your inbox [Become a Member](https://www.advisory.com/company/products/digital-subscription) This is for members only. Learn more. ### Click on ā€˜Become a Member’ to learn about the benefits of a Full-Access partnership with Advisory Board Never miss out on the latest innovative health care content tailored to you. [Become a Member](https://www.advisory.com/company/products/digital-subscription) #### Benefits Include: Unlimited access to research and resources Member-only access to events and trainings Expert-led consultation and facilitation The latest content delivered to your inbox [Become a Member](https://www.advisory.com/company/products/digital-subscription) # You Session Is Expiring Your session is about to expire. Click continue to stay logged in. Auto logout in seconds. [Continue](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) [Logout](https://www.advisory.com/daily-briefing/2020/07/24/covid-reinfection) ![AB](https://www.advisory.com/etc.clientlibs/advisory/clientlibs/clientlib-site/resources/images/ab-logo-loader.png) Thank you! Your updates have been made successfully. Oh no! There was a problem with your request. Error in form submission. Please try again.
Readable Markdown
Sporadic reports of Covid-19 patients seemingly becoming reinfected with the coronavirus have sparked doubts about whether people can ever gain immunity against the pathogen—and although current research suggests reinfection within a short time frame is unlikely, some researchers are hesitant to completely dismiss the idea. [**Your top resources for Covid-19 response and resilience**](https://www.advisory.com/research/covid-19) ### Doctors' stories, new studies raise concerns about coronavirus immunity Since the coronavirus pandemic began, there have been reports from doctors throughout the world about recovered Covid-19 patients seemingly becoming reinfected with the novel coronavirus, leaving some people doubting whether humans can become immune to the virus. For instance, a physician in New Jersey has [claimed](https://www.youtube.com/watch?v=Qjh4WuV94VQ&feature=youtu.be) that at least two of his Covid-19 patients had recovered from and tested negative for the coronavirus for months, but then started again experiencing symptoms of the disease and tested positive. One of those patients began showing symptoms of Covid-19 again after attending a party. "So that is … reinfection," the doctor said. The physician said the second recovered patient who appeared to be reinfected was a family member of the first patient. According to the doctor, that patient had tested negative for the coronavirus for several weeks, and even had developed enough antibodies to the virus that he was able to donate plasma for experimental Covid-19 treatments before again experiencing symptoms of the disease. Further, some recent studies also have sparked questions about coronavirus immunity. For example, results from a [study](https://www.medrxiv.org/content/10.1101/2020.07.09.20148429v1) recently released in preprint that hasn't yet been peer reviewed showed that antibodies developed against the coronavirus in people who'd been infected declined significantly within two to three months post infection. Moreover, Elitza Theel, director of the infectious diseases serology laboratory at the **Mayo Clinic** who was not involved in the study, said researchers are finding that coronavirus "antibodies will peak at about 20 to 30 days after symptom onset, and then they decline," and "\[t\]hey seem to decline much more rapidly in individuals that were asymptomatic or had mild forms of the disease." Given that antibodies help to neutralize the coronavirus and are believed to provide people with immunity against the pathogen, those findings have raised alarms among some observers that people may gain natural immunity to the coronavirus for only a few months. Robert Glatter, an assistant professor of emergency medicine at **Lenox Hill Hospital** and **Northwell Health**, explained that, if people could become reinfected with the coronavirus within a short period of time, it would mean that people may need to receive multiple vaccinations against the virus throughout the year to control the coronavirus' spread. "It would definitely be a predicament for public health, there's no question about that," especially if there isn't a vaccine against the virus, said Kamran Kadkhoda, medical director of immunopathology at the **Cleveland Clinic**. "In the absence of a vaccine, the main thing that we'd have against reinfection are these prevention measures" such as physical distancing and face masks, Kadkhoda explained. ### Research suggests coronavirus reinfection is unlikely But despite the anecdotal reports from doctors about patients becoming reinfected with the coronavirus, researchers say there's no evidence supporting the notion that people can become reinfected with the virus within a short time period. "I haven't heard of a case where it's been truly unambiguously demonstrated," said Marc Lipsitch, an epidemiologist at the **Harvard T.H. Chan School of Public Health**. For instance, South Korea's **Center for Disease Control and Prevention** in one [study](https://www.cdc.go.kr/board/board.es?mid=a30402000000&bid=0030&act=view&list_no=367267) confirmed that, among 285 cases of people who again tested positive for the coronavirus two months after receiving their initial positive test results (including some who were experiencing Covid-19 symptoms two months after their initial diagnoses), none of the patients' new samples contained enough virus particles to allow researchers to grow the virus from the samples in a lab. Researchers said those results indicated that the patients weren't actively infected with the virus, and the diagnostic tests likely had detected dead virus particles that remained in their bodies or generated false-positive positive results. Further, the researchers noted that none of the patients who re-tested positive for the coronavirus transmitted the pathogen to others. "It was pretty solid epidemiological and virological evidence that reinfection was not happening, at least in those people," Angela Rasmussen, a virologist at **Columbia University**, said. As for studies showing that antibodies for the novel coronavirus decline over time, researchers say that's how antibodies work for a host of viruses. Michael Mina, an immunologist at **Harvard University**, said although those studies have left some people "scratching their heads saying, 'What an extraordinarily odd virus that it's not leading to robust immunity,' … they're totally wrong." "It doesn't get more textbook than this," he added. And some research has resulted in different findings regarding coronavirus antibody levels over time. For example, results from a separate [study](https://www.medrxiv.org/content/10.1101/2020.07.14.20151126v1.full.pdf) that were released preprint and haven't been peer reviewed found that 120 patients who were infected with the coronavirus and experienced mild or moderate symptoms of Covid-19 had stable levels of coronavirus antibodies for at least three months post infection—and in some cases, those levels increased over that time. In addition, even if someone who had been infected with the coronavirus didn't develop antibodies for the pathogen, a person's T-cells and B-cells could fight off reinfection, public health experts say. "Even if you don't have a very high level of antibodies, you may be able to respond very rapidly to a challenge and nip it in the bud," said Michel Nussenzweig, head of the laboratory for molecular immunology at **Rockefeller University**. "You may be able to produce a better … faster response the second time around." Ultimately, Monica Gandhi, a professor of medicine and associate chief of infectious diseases at the **University of California-San Francisco**, said, "No one is yet believing in reinfection since there is no good scientific report on it." **So why do some people experience Covid-19 symptoms twice?** So why, then, do some people seemingly recover from Covid-19 but again experience symptoms later? Clinicians say more research is needed to answer the question of why some patients appear to fall ill with Covid-19 more than once, but some believe that such patients simply relapse because the coronavirus lays dormant in their bodies and reemerges—an occurrence that's been seen with some viruses that often result in lifetime immunity, such as the chickenpox virus, according to Daniel Griffin, an infectious diseases doctor and researcher at **Columbia University Medical Center**. It also may be possible that some patients experience a long course of infection that ramps up months after they first contract the coronavirus and initially experience symptoms of Covid-19, some experts have said. And others have speculated that some patients may contract a different virus with similar symptoms to Covid-19 and assume they've been reinfected with the coronavirus. ### But 'no one wants to dismiss the possibility' of reinfection completely However, while most experts say they don't think it's likely people can contract the coronavirus more than once within a short period of time, "no one wants to dismiss the possibility" of reinfection altogether, Gandhi said. And Griffin noted that, if researchers eventually find two different versions of the novel coronavirus' genetic code in one patient's body, it could point to two separate infections. "This is one of those things I really don't want to be true," Griffin said, "\[b\]ut a lot of us are starting to say, 'I'm willing to entertain it as a possibility. Let's keep our eyes out and start watching'" (Johnson/Cha, [*Washington Post*](https://www.washingtonpost.com/health/2020/07/22/can-you-get-coronavirus-twice/?utm_source=rss&utm_medium=referral&utm_campaign=wp_health), 7/22; Resnick/Irfan, [*Vox*](https://www.vox.com/2020/7/22/21324729/getting-covid-19-twice-immunity-antibodies-vaccine-herd-immunity), 7/22; Mandavilli, [*New York Times*](https://www.nytimes.com/2020/07/22/health/covid-antibodies-herd-immunity.html?campaign_id=9&emc=edit_nn_20200723&instance_id=20544&nl=the-morning&regi_id=79817166&segment_id=34125&te=1&user_id=c57f9051ed41ab7de15bac33092fda41), 7/22; Craig, [Monmouth *Daily Voice*](https://dailyvoice.com/new-jersey/monmouth/news/central-jersey-doctor-reports-patients-reinfected-with-coronavirus/790555/), 7/9; Sternlicht, [*Forbes*](https://www.forbes.com/sites/alexandrasternlicht/2020/05/18/south-korea-says-patients-who-re-tested-positive-after-recovering-were-no-longer-infectious/#3167cd8b70a6), 5/19).
Shard148 (laksa)
Root Hash12271137716583932748
Unparsed URLcom,advisory!www,/daily-briefing/2020/07/24/covid-reinfection s443