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| URL | https://pubmed.ncbi.nlm.nih.gov/35412612/ |
| Last Crawled | 2025-12-20 04:03:37 (3 months ago) |
| First Indexed | 2022-04-13 05:37:37 (3 years ago) |
| HTTP Status Code | 200 |
| Meta Title | Comparative Effectiveness of mRNA and Inactivated Whole-Virus Vaccines Against Coronavirus Disease 2019 Infection and Severe Disease in Singapore |
| Meta Description | Compared with individuals vaccinated with Pfizer-BioNTech/Comirnaty, recipients of Sinovac-CoronaVac and Sinopharm were 2.37 (95% CI, 2.29-2.46) and 1.62 (95% CI, 1.43-1.85) times more likely to be infected with coronavirus disease 19, respectively, while individuals vaccinated with Moderna were 0.4 … |
| Meta Canonical | null |
| Boilerpipe Text | Clin Infect Dis
.
2022 Oct 12;75(8):1442-1445.
doi: 10.1093/cid/ciac288.
Affiliations
1
Ministry of Health, Singapore.
2
National Centre for Infectious Diseases, Singapore.
3
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
4
Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
5
Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.
6
Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
PMID:
35412612
PMCID:
PMC9047219
DOI:
10.1093/cid/ciac288
Abstract
Compared with individuals vaccinated with Pfizer-BioNTech/Comirnaty, recipients of Sinovac-CoronaVac and Sinopharm were 2.37 (95% CI, 2.29-2.46) and 1.62 (95% CI, 1.43-1.85) times more likely to be infected with coronavirus disease 19, respectively, while individuals vaccinated with Moderna were 0.42 (95% CI, 0.25-0.70) times less likely to develop severe disease.
Keywords:
COVID-19; SARS-CoV-2; inactivated vaccine; mRNA vaccine; vaccines.
© The Author(s) 2022. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
MeSH terms
COVID-19 Vaccines
COVID-19* / prevention & control
Humans
RNA, Messenger
Singapore / epidemiology
Vaccines, Inactivated
Substances
COVID-19 Vaccines
RNA, Messenger
Vaccines, Inactivated |
| Markdown | # Comparative Effectiveness of mRNA and Inactivated Whole-Virus Vaccines Against Coronavirus Disease 2019 Infection and Severe Disease in Singapore
Clin Infect Dis. 2022 Oct 12;75(8):1442-1445. doi: 10.1093/cid/ciac288.
### Authors
[M Premikha](https://pubmed.ncbi.nlm.nih.gov/?term=Premikha+M&cauthor_id=35412612) [1](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-1 "Ministry of Health, Singapore.") , [Calvin J Chiew](https://pubmed.ncbi.nlm.nih.gov/?term=Chiew+CJ&cauthor_id=35412612) [1](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-1 "Ministry of Health, Singapore.") , [Wycliffe E Wei](https://pubmed.ncbi.nlm.nih.gov/?term=Wei+WE&cauthor_id=35412612) [1](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-1 "Ministry of Health, Singapore.") , [Yee Sin Leo](https://pubmed.ncbi.nlm.nih.gov/?term=Leo+YS&cauthor_id=35412612) [2](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-2 "National Centre for Infectious Diseases, Singapore.") [3](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-3 "Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.") [4](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-4 "Yong Loo Lin School of Medicine, National University of Singapore, Singapore.") [5](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-5 "Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.") [6](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-6 "Saw Swee Hock School of Public Health, National University of Singapore, Singapore.") , [Benjamin Ong](https://pubmed.ncbi.nlm.nih.gov/?term=Ong+B&cauthor_id=35412612) [1](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-1 "Ministry of Health, Singapore.") [4](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-4 "Yong Loo Lin School of Medicine, National University of Singapore, Singapore.") , [David Chien Lye](https://pubmed.ncbi.nlm.nih.gov/?term=Lye+DC&cauthor_id=35412612) [2](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-2 "National Centre for Infectious Diseases, Singapore.") [3](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-3 "Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.") [4](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-4 "Yong Loo Lin School of Medicine, National University of Singapore, Singapore.") [5](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-5 "Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.") , [Vernon J Lee](https://pubmed.ncbi.nlm.nih.gov/?term=Lee+VJ&cauthor_id=35412612) [1](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-1 "Ministry of Health, Singapore.") [6](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-6 "Saw Swee Hock School of Public Health, National University of Singapore, Singapore.") , [Kelvin Bryan Tan](https://pubmed.ncbi.nlm.nih.gov/?term=Tan+KB&cauthor_id=35412612) [1](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-1 "Ministry of Health, Singapore.") [6](https://pubmed.ncbi.nlm.nih.gov/35412612/#affiliation-6 "Saw Swee Hock School of Public Health, National University of Singapore, Singapore.")
### Affiliations
- 1 Ministry of Health, Singapore.
- 2 National Centre for Infectious Diseases, Singapore.
- 3 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
- 4 Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
- 5 Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.
- 6 Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
- PMID: [35412612](https://pubmed.ncbi.nlm.nih.gov/35412612/)
- PMCID: [PMC9047219](https://pmc.ncbi.nlm.nih.gov/articles/PMC9047219/)
- DOI: [10\.1093/cid/ciac288](https://doi.org/10.1093/cid/ciac288)
## Abstract
Compared with individuals vaccinated with Pfizer-BioNTech/Comirnaty, recipients of Sinovac-CoronaVac and Sinopharm were 2.37 (95% CI, 2.29-2.46) and 1.62 (95% CI, 1.43-1.85) times more likely to be infected with coronavirus disease 19, respectively, while individuals vaccinated with Moderna were 0.42 (95% CI, 0.25-0.70) times less likely to develop severe disease.
**Keywords:** COVID-19; SARS-CoV-2; inactivated vaccine; mRNA vaccine; vaccines.
© The Author(s) 2022. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
## MeSH terms
- COVID-19 Vaccines
- COVID-19\* / prevention & control
- Humans
- RNA, Messenger
- Singapore / epidemiology
- Vaccines, Inactivated
## Substances
- COVID-19 Vaccines
- RNA, Messenger
- Vaccines, Inactivated |
| Readable Markdown | null |
| Shard | 129 (laksa) |
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| Unparsed URL | gov,nih!nlm,ncbi,pubmed,/35412612/ s443 |