âšī¸ Skipped - page is already crawled
| Filter | Status | Condition | Details |
|---|---|---|---|
| HTTP status | PASS | download_http_code = 200 | HTTP 200 |
| Age cutoff | PASS | download_stamp > now() - 6 MONTH | 3.4 months ago |
| History drop | PASS | isNull(history_drop_reason) | No drop reason |
| Spam/ban | PASS | fh_dont_index != 1 AND ml_spam_score = 0 | ml_spam_score=0 |
| Canonical | PASS | meta_canonical IS NULL OR = '' OR = src_unparsed | Not set |
| Property | Value |
|---|---|
| URL | https://pubmed.ncbi.nlm.nih.gov/18811240/ |
| Last Crawled | 2026-01-02 18:58:07 (3 months ago) |
| First Indexed | 2020-05-23 20:41:10 (5 years ago) |
| HTTP Status Code | 200 |
| Meta Title | Antibiotic-associated diarrhea: epidemiology, trends and treatment |
| Meta Description | A common complication of antibiotic use is the development of gastrointestinal disease. This complication ranges from mild diarrhea to pseudomembranous colitis. Outbreaks of antibiotic-associated diarrhea (AAD) may also occur in healthcare settings, usually caused by Clostridium difficile. AAD typic âĻ |
| Meta Canonical | null |
| Boilerpipe Text | Future Microbiol
.
2008 Oct;3(5):563-78.
doi: 10.2217/17460913.3.5.563.
Affiliation
1
Department of Health Services Research & Development, Puget Sound Veterans Administration, Healthcare System, Seattle, WA 98101, USA. lynne.mcfarland@va.gov
PMID:
18811240
DOI:
10.2217/17460913.3.5.563
Abstract
A common complication of antibiotic use is the development of gastrointestinal disease. This complication ranges from mild diarrhea to pseudomembranous colitis. Outbreaks of antibiotic-associated diarrhea (AAD) may also occur in healthcare settings, usually caused by Clostridium difficile. AAD typically occurs in 5-35% of patients taking antibiotics and varies depending upon the specific type of antibiotic, the health of the host and exposure to pathogens. The pathogenesis of AAD may be mediated through the disruption of the normal microbiota resulting in pathogen overgrowth or metabolic imbalances. The key to addressing AAD is prompt diagnosis followed by effective treatment and institution of control measures. Areas of active research include the search for other etiologies and more effective treatments.
Publication types
Review
MeSH terms
Anti-Bacterial Agents / adverse effects*
Clostridioides difficile / isolation & purification*
Cross Infection / drug therapy
Cross Infection / epidemiology
Cross Infection / microbiology
Diarrhea / drug therapy
Diarrhea / epidemiology*
Diarrhea / microbiology
Disease Outbreaks
Enterocolitis, Pseudomembranous / drug therapy
Enterocolitis, Pseudomembranous / epidemiology*
Enterocolitis, Pseudomembranous / microbiology
Humans
Substances
Anti-Bacterial Agents |
| Markdown | # Antibiotic-associated diarrhea: epidemiology, trends and treatment
Future Microbiol. 2008 Oct;3(5):563-78. doi: 10.2217/17460913.3.5.563.
### Author
[Lynne V McFarland](https://pubmed.ncbi.nlm.nih.gov/?term=McFarland+LV&cauthor_id=18811240) [1](https://pubmed.ncbi.nlm.nih.gov/18811240/#affiliation-1 "Department of Health Services Research & Development, Puget Sound Veterans Administration, Healthcare System, Seattle, WA 98101, USA. lynne.mcfarland@va.gov")
### Affiliation
- 1 Department of Health Services Research & Development, Puget Sound Veterans Administration, Healthcare System, Seattle, WA 98101, USA. lynne.mcfarland@va.gov
- PMID: [18811240](https://pubmed.ncbi.nlm.nih.gov/18811240/)
- DOI: [10\.2217/17460913.3.5.563](https://doi.org/10.2217/17460913.3.5.563)
## Abstract
A common complication of antibiotic use is the development of gastrointestinal disease. This complication ranges from mild diarrhea to pseudomembranous colitis. Outbreaks of antibiotic-associated diarrhea (AAD) may also occur in healthcare settings, usually caused by Clostridium difficile. AAD typically occurs in 5-35% of patients taking antibiotics and varies depending upon the specific type of antibiotic, the health of the host and exposure to pathogens. The pathogenesis of AAD may be mediated through the disruption of the normal microbiota resulting in pathogen overgrowth or metabolic imbalances. The key to addressing AAD is prompt diagnosis followed by effective treatment and institution of control measures. Areas of active research include the search for other etiologies and more effective treatments.
## Publication types
- Review
## MeSH terms
- Anti-Bacterial Agents / adverse effects\*
- Clostridioides difficile / isolation & purification\*
- Cross Infection / drug therapy
- Cross Infection / epidemiology
- Cross Infection / microbiology
- Diarrhea / drug therapy
- Diarrhea / epidemiology\*
- Diarrhea / microbiology
- Disease Outbreaks
- Enterocolitis, Pseudomembranous / drug therapy
- Enterocolitis, Pseudomembranous / epidemiology\*
- Enterocolitis, Pseudomembranous / microbiology
- Humans
## Substances
- Anti-Bacterial Agents |
| Readable Markdown | null |
| Shard | 129 (laksa) |
| Root Hash | 7295144728021232729 |
| Unparsed URL | gov,nih!nlm,ncbi,pubmed,/18811240/ s443 |