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URLhttps://pubmed.ncbi.nlm.nih.gov/18811240/
Last Crawled2026-01-02 18:58:07 (3 months ago)
First Indexed2020-05-23 20:41:10 (5 years ago)
HTTP Status Code200
Meta TitleAntibiotic-associated diarrhea: epidemiology, trends and treatment
Meta DescriptionA common complication of antibiotic use is the development of gastrointestinal disease. This complication ranges from mild diarrhea to pseudomembranous colitis. Outbreaks of antibiotic-associated diarrhea (AAD) may also occur in healthcare settings, usually caused by Clostridium difficile. AAD typic â€Ļ
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Future Microbiol . 2008 Oct;3(5):563-78. doi: 10.2217/17460913.3.5.563. Affiliation 1 Department of Health Services Research & Development, Puget Sound Veterans Administration, Healthcare System, Seattle, WA 98101, USA. lynne.mcfarland@va.gov PMID: 18811240 DOI: 10.2217/17460913.3.5.563 Abstract A common complication of antibiotic use is the development of gastrointestinal disease. This complication ranges from mild diarrhea to pseudomembranous colitis. Outbreaks of antibiotic-associated diarrhea (AAD) may also occur in healthcare settings, usually caused by Clostridium difficile. AAD typically occurs in 5-35% of patients taking antibiotics and varies depending upon the specific type of antibiotic, the health of the host and exposure to pathogens. The pathogenesis of AAD may be mediated through the disruption of the normal microbiota resulting in pathogen overgrowth or metabolic imbalances. The key to addressing AAD is prompt diagnosis followed by effective treatment and institution of control measures. Areas of active research include the search for other etiologies and more effective treatments. Publication types Review MeSH terms Anti-Bacterial Agents / adverse effects* Clostridioides difficile / isolation & purification* Cross Infection / drug therapy Cross Infection / epidemiology Cross Infection / microbiology Diarrhea / drug therapy Diarrhea / epidemiology* Diarrhea / microbiology Disease Outbreaks Enterocolitis, Pseudomembranous / drug therapy Enterocolitis, Pseudomembranous / epidemiology* Enterocolitis, Pseudomembranous / microbiology Humans Substances Anti-Bacterial Agents
Markdown
# Antibiotic-associated diarrhea: epidemiology, trends and treatment Future Microbiol. 2008 Oct;3(5):563-78. doi: 10.2217/17460913.3.5.563. ### Author [Lynne V McFarland](https://pubmed.ncbi.nlm.nih.gov/?term=McFarland+LV&cauthor_id=18811240) [1](https://pubmed.ncbi.nlm.nih.gov/18811240/#affiliation-1 "Department of Health Services Research & Development, Puget Sound Veterans Administration, Healthcare System, Seattle, WA 98101, USA. lynne.mcfarland@va.gov") ### Affiliation - 1 Department of Health Services Research & Development, Puget Sound Veterans Administration, Healthcare System, Seattle, WA 98101, USA. lynne.mcfarland@va.gov - PMID: [18811240](https://pubmed.ncbi.nlm.nih.gov/18811240/) - DOI: [10\.2217/17460913.3.5.563](https://doi.org/10.2217/17460913.3.5.563) ## Abstract A common complication of antibiotic use is the development of gastrointestinal disease. This complication ranges from mild diarrhea to pseudomembranous colitis. Outbreaks of antibiotic-associated diarrhea (AAD) may also occur in healthcare settings, usually caused by Clostridium difficile. AAD typically occurs in 5-35% of patients taking antibiotics and varies depending upon the specific type of antibiotic, the health of the host and exposure to pathogens. The pathogenesis of AAD may be mediated through the disruption of the normal microbiota resulting in pathogen overgrowth or metabolic imbalances. The key to addressing AAD is prompt diagnosis followed by effective treatment and institution of control measures. Areas of active research include the search for other etiologies and more effective treatments. ## Publication types - Review ## MeSH terms - Anti-Bacterial Agents / adverse effects\* - Clostridioides difficile / isolation & purification\* - Cross Infection / drug therapy - Cross Infection / epidemiology - Cross Infection / microbiology - Diarrhea / drug therapy - Diarrhea / epidemiology\* - Diarrhea / microbiology - Disease Outbreaks - Enterocolitis, Pseudomembranous / drug therapy - Enterocolitis, Pseudomembranous / epidemiology\* - Enterocolitis, Pseudomembranous / microbiology - Humans ## Substances - Anti-Bacterial Agents
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Shard129 (laksa)
Root Hash7295144728021232729
Unparsed URLgov,nih!nlm,ncbi,pubmed,/18811240/ s443