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URLhttps://mashable.com/article/best-memes-of-2025-list
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Meta TitleUsing AI for health questions? Here are 4 tips for the most accurate answers.
Meta DescriptionFrom 100 men vs. a gorilla, to jokes about the new pope, and so much more — we've had some good memes in 2025.
Meta Canonicalcom,mashable!/article/ai-chatgpt-chatbot-claude-health-questions s443
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Every day, millions of people turn to an artificial intelligence chatbot like Claude, Gemini , and ChatGPT to ask a question about their physical health.  They may not know that getting the correct answer is harder than it appears, no matter how authoritatively the chatbot responds.  Three recent studies indicate that large language models aren't as reliable as users may hope.  One study that tested chatbots' ability to detect health misinformation failed more often than not in certain scenarios. Another study conducted by some of the same researchers found that ChatGPT Health , a dedicated health and wellness service that debuted in January, "under-triaged" slightly more than half of cases presented to it, including emergency conditions that required immediate medical care.  "I think that consumers should have a high degree of caution, like almost an abundance of caution," Dr. Girish N. Nadkarni, an internist and nephrologist at Mt. Sinai, who co-authored both of the studies, said of querying a chatbot for health advice.  This may surprise users who hear that chatbots can easily pass a medical exam, even if they sometimes hallucinate outside of a testing environment. Yet the recent research points to a complex, somewhat hidden problem. The way humans interact with chatbots, and the manner in which they're designed to expertly please, creates unpredictability. Those factors are never a challenge for AI being tested on textbook medical questions.  If you want to start, or continue using, a chatbot for your health questions, take these expert-recommended steps as you come up with prompts:  1. Test the model with misinformation or inaccuracies first.  Nadkarni, an AI health researcher and director of Mt. Sinai's Hasso Plattner Institute for Digital Health, says it's important to ask the chatbot about medical misinformation or known falsehoods prior to querying it about specific health questions.  Challenge the chatbot, for example, to comment on a conspiracy theory about a vaccine, such as whether it agrees that the COVID-19 shot contains a microchip to track people .  Or prompt it to respond to a slightly more challenging health controversy, like the safety of fluoride in drinking water . While researchers have found evidence that extremely high levels of fluoride can be dangerous, experts agree that current standard levels remain safe .  Testing the chatbot with misinformation should provide a revealing baseline for the potential accuracy of its other responses, Nadkarni says.  A new Mashable series, AI + Health, will examine how artificial intelligence is changing the medical and health landscape. We'll explore how to use AI to decipher your blood work , how to keep your health data safe , learn how two women are using AI to detect a dangerous form of heart disease , and much more. His recent study found that several general-purpose chatbots, including ChatGPT, inconsistently detected misinformation across many scenarios. Success rates depended on the context, like whether it was presented in a social media post versus a medical note. They also failed often when presented with specific logical fallacies.  For example, when the prompt with misinformation appeared to come from a physician, via a real note drawn from an electronic health record, the chatbot was more likely to miss the falsehoods.  If the chatbot you're consulting agrees with statements you know to be partially or wholly false, Nadkarni says avoid asking it for its opinion on your personal health questions.  2. Consider the cues or information you may be giving the chatbot.  When Nadkarni and his colleagues tested ChatGPT Health earlier this year, they discovered that how users frame their symptoms may influence the model's accuracy.  If, for example, the prompt included statements about friends or family downplaying the symptoms in question, ChatGPT Health's recommendation shifted in that direction as well. In those instances, the chatbot was 11 times more likely not to send the patient to the emergency room, even when their symptoms indicated a life-threatening condition.  The results were published as a peer-reviewed advance paper in Nature Medicine .  OpenAI objected to the results, arguing that the study methods didn't represent how people use ChatGPT over multiple chats, sharing information and answering follow-up questions. Karan Singhal, who leads the Health AI team at OpenAI, told Mashable in a statement that its own benchmarking indicates that GPT-5 models "correctly refer emergency cases nearly 99 percent of the time." Nadkarni said that while he welcomed debate, the criticism "missed the point." He said that while ChatGPT Health correctly identified abnormalities in the presented data, it reasoned past them. "The issue is not missing information but incorrect conclusions despite correct data," Nadkarni told Mashable. A separate recent study, also published in Nature Medicine but by a different group of researchers, randomly assigned 1,298 human participants to present a predetermined medical scenario to an AI chatbot (GPT-4o, Llama 3, and Command R+) or a source of their choice, including Google.  When the chatbots were tested simply on the scenarios, they correctly identified the condition in nearly 95 percent of the cases. Once humans began posing questions about the scenario, however, the same chatbots could accurately pinpoint the condition in only about a third of cases.  "Despite LLMs alone having high proficiency in the task, the combination of LLMs and human users was no better than the control group in assessing clinical acuity and worse at identifying relevant conditions," the researchers wrote.  Many participants lacked an accurate understanding of the symptom severity, which contributed to the failure rate.  3. Take into account whether you're a novice or expert.  This is the kind of dynamic that Dr. Robert Wachter keeps in mind when he considers how people prompt a chatbot for answers to medical questions.  Wachter, professor and chair of the Department of Medicine at the University of California, San Francisco, routinely uses OpenEvidence, an AI chatbot designed for physicians and healthcare professionals. He finds the AI's answers to complex medical questions largely fast, accurate, and helpful.  Wachter, author of " A Giant Leap: How AI is Transforming Healthcare and What That Means for Our Future ," also believes that general-purpose and health-specific chatbots can be very useful to the average patient compared to a basic Google search.  Yet he's also aware that he approaches AI chatbots as an expert with 40 years of medical experience and can quickly identify the most relevant details to include in a prompt.  "A patient has absolutely no ability to do that — to know what are the salient facts of all the things that might be going on in terms of their current symptoms, in terms of their past history, in terms of their medication," he says. "So what they put into the prompt may be not exactly right." Wachter says that recent research demonstrates a clear risk for patients when they don't know the right information to use in a prompt, and when they misinterpret the chatbot's response.  Still, he believes that more often than not, an AI chatbot is better than nothing, provided patients focus on including relevant health history and current symptoms, and use it with a "buyer beware" attitude.  In particular, Wachter says he wouldn't trust a chatbot for symptoms that may indicate a life-threatening emergency, such as severe chest pain, new shortness of breath or confusion, or weakness on one side of the body.  4. Ask for references and cross-check the answer.  When a chatbot gives its response, Nadkarni suggests taking the time to ask for its references for the information provided.  It's not enough to scan a list of links, either. Nadkarni recommends clicking links to evaluate the source. If the chatbot has based its answer on a "shady Reddit post," Nadkarni says it's probably not trustworthy.  On the other hand, if the reference directs you to a verifiable medical organization, like the American Medical Association, that should be reassuring.  Nadkarni acknowledges that while individual users may not agree with the views of a health organization or authority, the information usually reflects medical consensus based on the best current evidence.  Wachter also recommends asking a second AI chatbot that you trust to weigh in on the same health information you shared with the first chatbot to see if it arrives at the same conclusion. That can be a good indication that the response is useful and reliable.   Despite Wachter's enthusiasm for AI chatbots in healthcare, he believes the recent studies indicate substantial room for improvement. He imagines AI tools that act more like a "good doctor," engaging the user in conversation to elicit all the relevant information before suggesting a diagnosis or action, like taking medication or going to the emergency room.  "I think the patient-facing tools are not where they're going to end up," he says of present-day AI chatbots that field health questions. "Ultimately, the tool for a patient is going to be much more [like a doctor] than the tools now." ________________________________________________________________________________________________________ The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives. Disclosure: Ziff Davis, Mashable’s parent company, in April 2025 filed a lawsuit against OpenAI, alleging it infringed Ziff Davis copyrights in training and operating its AI systems.
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See the list. A gorilla, a new pope, and so much more. By [Tim Marcin](https://mashable.com/author/tim-marcin) ![close-up of man's face](https://helios-i.mashable.com/imagery/authors/03Lp0IEBs8IXYimAPV3941z/image.fill.size_400x400.v1723813500.jpg) Tim Marcin Associate Editor, Culture Tim Marcin is an Associate Editor on the culture team at Mashable, where he mostly digs into the weird parts of the internet. You'll also see some coverage of memes, tech, sports, trends, and the occasional hot take. You can find him on [Bluesky](https://bsky.app/profile/timmarcin.bsky.social) (sometimes), [Instagram](https://www.instagram.com/tim_marcin/) (infrequently), or eating Buffalo wings (as often as possible). [Read Full Bio](https://mashable.com/author/tim-marcin) on December 11, 2025 [Share on Facebook](https://www.facebook.com/sharer.php?u=https%3A%2F%2Fmashable.com%2Farticle%2Fbest-memes-of-2025-list "(opens in a new window)") [Share on Twitter](https://twitter.com/intent/tweet?url=https%3A%2F%2Fmashable.com%2Farticle%2Fbest-memes-of-2025-list&text=The+best+memes+of+2025%2C+from+6-7+to+God%27s+country.+See+the+list. "(opens in a new window)") [Share on Flipboard](https://share.flipboard.com/bookmarklet/popout?v=2&url=https%3A%2F%2Fmashable.com%2Farticle%2Fbest-memes-of-2025-list&title=The+best+memes+of+2025%2C+from+6-7+to+God%27s+country.+See+the+list. "(opens in a new window)") ![a compilation of popular memes from 2025](https://helios-i.mashable.com/imagery/articles/0251onwkStcVWoAuZeJ2osS/hero-image.fill.size_1248x702.v1765445168.jpg) All the best memes, all in one place. Credit: Ian Moore / Mashable Composite; Alan Tunnicliffe Photography / Moment / millionsjoker / iStock / NBC / NBCUniversal / Christopher Furlong / Getty Images News / Getty *** [![The Best of 2025](https://helios-i.mashable.com/imagery/series/02g7jyZnmykF9Et99iuBmcC/logo.fill.size_400x400.v1765318623.png)](https://mashable.com/series/best-of-the-year-2025) Join Mashable as we look back at the viral videos, breakout movies, memes, dating trends, tech buzz, scientific breakthroughs, and more moments that defined 2025\! *** Memes are few and far between in 2025, but there are still some good ones. Why are [memes](https://mashable.com/category/memes) so rare? Simply put: [TikTok](https://mashable.com/category/tiktok). The heart of digital culture has migrated to TikTok, which is a short-form video platform. So there remain memes of a sort — they're mostly called [TikTok trends](https://mashable.com/article/muffins-freezer-tiktok-trend-vine) — but the text-and-image-based memes of years past? Those are harder to come by. Another reason for that? Twitter (RIP). When [Elon Musk](https://mashable.com/category/elon-musk) [bought the app](https://mashable.com/article/elon-musk-buys-twitter) and then reimagined it as [X](https://mashable.com/category/twitter), well, that fractured the central text-based social platform. Previously, a meme was born on Twitter, then worked its way to [Reddit](https://mashable.com/category/reddit), then [Instagram](https://mashable.com/category/instagram), then, weeks later, [Facebook](https://mashable.com/category/facebook). With X becoming increasingly difficult to use and [less popular](https://mashable.com/article/elon-musk-x-declining-user-base-2025), that lifecycle has mostly disappeared. *** **You May Also Like** *** *** But memes, to some extent, persist. On TikTok, [Bluesky](https://mashable.com/article/bluesky-gaining-ground-on-competitor-meta-threads), Instagram, and, yes, even X. We've tracked them closely and collected 12 of the best memes of 2025. ## 1\. The endless 6-7 of it all I personally cannot wait until we exit the era of 6-7. [Dictionary.com](http://dictionary.com/ "(opens in a new window)") made it their word of the year, for better or worse ([worse...definitely worse](https://mashable.com/article/dictionary-word-year-6-7-six-seven-2025)). In case you missed it, [we explained the origins and meaning](https://mashable.com/article/what-is-6-7-meme-explained-six-seven-meaning), but the TL;DR is that it means nothing. It's just a fun thing to say. And kids, especially, find it hilarious. It's so prevalent that it made it [onto *South Park*](https://x.com/mashable/status/1978955381809328372?s=20 "(opens in a new window)"). > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/abitterth1ng/status/1988792980979999134 "(Opens in a new tab) (opens in a new window)") SEE ALSO: [What does '6-7' mean? Here's why kids are saying 'six, seven' over and over.](https://mashable.com/article/what-is-6-7-meme-explained-six-seven-meaning) ## 2\. Trump take egg Just before President Donald Trump's [extreme tariffs](https://mashable.com/category/tariffs) sent the U.S. economy into a tailspin, [the internet had jokes...jokes about egg](https://mashable.com/article/trump-take-egg-meme-explained). It was a bit of classic internet absurdism, poking fun at people who voted for Trump for lower egg prices...as egg prices skyrocketed. SEE ALSO: [The 'Trump take egg' meme is an absurdly layered joke](https://mashable.com/article/trump-take-egg-meme-explained) ## 3\. The Anthropologie rock The [internet collectively created a bit](https://mashable.com/article/anthropologie-rocks-tiktok-trend) that the famously pricey retailer Anthropologie was selling rocks for four figures. It was all based on a [joke from TikTokker @phoebeadams112](https://www.tiktok.com/@phoebeadams112/video/7550002016878185742 "(opens in a new window)"), who pranked their boyfriend by claiming she paid \$150 for a rock from Anthropologie. It eventually grew so large that [the brand itself](https://www.instagram.com/reel/DO6H6QiDYZr/ "(opens in a new window)") began joking about it. > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/alexandergold/status/1969454451053511115 "(Opens in a new tab) (opens in a new window)") ## 4\. The Duke-*White Lotus* debacle It was the (missed) shot heard round the world: Duke crashed out of 2025's March Madness in a stunning chokejob. It was kismet: In this year's season of HBO's [*The White Lotus*](https://mashable.com/category/the-white-lotus), Timothy Ratliff (Jason Isaacs) spirals out of control, often in a Duke t-shirt. The [memes practically made themselves](https://mashable.com/article/white-lotus-duke-memes-march-madness). > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/TristanUda/status/1908729613779362094 "(Opens in a new tab) (opens in a new window)") > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/lilydsmith/status/1908736578840633599 "(Opens in a new tab) (opens in a new window)") ## 5\. Get me to God's country Morgan Wallen [inspired one of the best memes of 2025](https://mashable.com/article/morgan-wallen-gods-country-snl-memes) after he stormed off the stage at [*Saturday Night Live*](https://mashable.com/category/snl)as the credits rolled. He later, hilariously, posted an image of a private jet to his Instagram stories, captioning it, "Get me to God's country." It was assumed that country star Wallen, who had a previous *SNL* appearance cancelled for violating COVID protocols and, soon after, faced major ire when footage of him saying the N-word surfaced, was signaling to his fans he was ready to leave the liberal big city. People mostly poked fun at the idea, since, you know, the super-rich guy was leaving NYC in a private jet. Mashable Trend Report Decode what’s viral, what’s next, and what it all means. Sign up for Mashable’s weekly Trend Report newsletter. Use this instead By clicking Sign Me Up, you confirm you are 16+ and agree to our [Terms of Use](https://www.ziffdavis.com/terms-of-use "(opens in a new window)") and [Privacy Policy](https://www.ziffdavis.com/ztg-privacy-policy "(opens in a new window)"). Thanks for signing up\! > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/queensofbravo/status/1906728416465891375 "(Opens in a new tab) (opens in a new window)") > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/BriAnimator_/status/1906714587539378517 "(Opens in a new tab) (opens in a new window)") ## 6\. The little French fish There was a period of time in 2025 when FYPs everywhere [were dominated by a little French fish](https://mashable.com/article/le-poisson-steve-fish-tiktok-for-you-page). It was just a little orange fish named Steve. That was really it. But it ruled. ## 7\. The conclave memes There were few bigger internet moments in 2025 than [the conclave to decide the new pope](https://mashable.com/article/pope-conclave-internet-obsession). That seems odd, and it was. But the memes and jokes about the conclave were hilarious and constant. We got Brat edits, fancams, and breathless coverage online. It was great and quite strange. > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/shecononmyclave/status/1920108309832450493 "(Opens in a new tab) (opens in a new window)") > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/tiramiiiiiiisu/status/1914622491709890769 "(Opens in a new tab) (opens in a new window)") ## 8\. Holy airball To keep things on the holy side, [TikTok had lots of memes about holy f-ing airballs](https://mashable.com/article/tiktok-holy-fing-airball-trend) in 2025. In essence, posters would use the phrase to subvert people's expectations — often in a braggy way. ## 9\. 100 men vs. 1 gorilla And, finally, we have [perhaps the biggest meme of 2025](https://mashable.com/article/internet-men-fighting-gorilla-argument): 100 men vs. one gorilla. The internet has long loved to imagine silly, man vs. animal fights. And in 2025, we *really* focused on 100 dudes taking on a gorilla. Real scientists even weighed in, which is fantastic. (In general, if the guys stay organized and selfless, they'd win.) It became a meme for days. SEE ALSO: [The internet can’t stop arguing over 100 men fighting 1 gorilla](https://mashable.com/article/internet-men-fighting-gorilla-argument) > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/talleyberrybaby/status/1916449204785868858 "(Opens in a new tab) (opens in a new window)") > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/e161618/status/1917302017464095089 "(Opens in a new tab) (opens in a new window)") The whole gorilla debate was unserious and funny, just how memes should be. ## 10\. The *Weapons* run Not to spoil [the movie *Weapons*](https://mashable.com/article/weapons-review)— but to mildly spoil *Weapons —* a scene features kids running in a very specific manner. People quickly started copying the run, [making it an IRL meme in no time at all](https://mashable.com/article/weapons-run-meme). People also posted images of the scene, adding funny or relatable captions. > [This Tweet is currently unavailable. It might be loading or has been removed.](https://twitter.com/FinalDude78/status/1956442064704745768 "(Opens in a new tab) (opens in a new window)") ## 11\. The Group 7 fad Speaking of memes involving the number seven, [remember the whole Group 7 thing](https://mashable.com/article/group-7-meme-trend-examples-explained-tiktok)? It stemmed from the promotion of the song "So Unfair" by singer [Sophia James](https://www.tiktok.com/@sophiajamesmusic "(opens in a new window)"). She posted seven promotional videos, grouping folks by which video they saw. Weirdly, the Group 7 TikTok took off, and people made jokes about how elite that group was. It was random and an interesting flash in the pan. "I was just trying to promote my song. That's all it was," James [told Mashable over email](https://mashable.com/article/the-group-7-tiktok-trend-explained-sophia-james). ## 12\. Bobby Hill's wabi-sabi There's beauty in imperfection, and there's beauty in Bobby Hill's voice. It's no wonder a clip from *King of the Hill* featuring Bobby waxing about wabi-sabi took off. It [became a meme on TikTok](https://mashable.com/article/tiktok-bobby-king-hill-wabi-sabi-viral-meme) to use that sound and show off the imperfect things in life, such as crooked teeth or bad haircuts. So sure, we didn't get *as many* memes this year, but we certainly had a decent amount of fun online. And as Bobby Hill taught us, perfection is overrated. Topics [TikTok](https://mashable.com/category/tiktok) [X/Twitter](https://mashable.com/category/twitter) [Memes](https://mashable.com/category/memes) ![close-up of man's face](https://helios-i.mashable.com/imagery/authors/03Lp0IEBs8IXYimAPV3941z/image.fill.size_100x100.v1723813500.jpg) Tim Marcin Associate Editor, Culture Tim Marcin is an Associate Editor on the culture team at Mashable, where he mostly digs into the weird parts of the internet. You'll also see some coverage of memes, tech, sports, trends, and the occasional hot take. You can find him on [Bluesky](https://bsky.app/profile/timmarcin.bsky.social "(opens in a new window)") (sometimes), [Instagram](https://www.instagram.com/tim_marcin/ "(opens in a new window)") (infrequently), or eating Buffalo wings (as often as possible). ![Mashable Potato](https://mashable.com/images/seamless-keep-scrolling.png) [Home](https://mashable.com/) \> [Life](https://mashable.com/life) \> [Health & Wellness](https://mashable.com/category/health-wellness) # Using AI for health questions? Here are 4 tips for the most accurate answers. AI chatbots can still get medical questions wrong, according to new research. By [Rebecca Ruiz](https://mashable.com/author/rebecca-ruiz) ![Rebecca Ruiz](https://helios-i.mashable.com/imagery/authors/01s9tVH6oSuivSFQB7tUAV3/image.fill.size_200x200.v1624381012.jpg) Rebecca Ruiz Senior Reporter Rebecca Ruiz is a Senior Reporter at Mashable. She frequently covers mental health, digital culture, and technology. Her areas of expertise include suicide prevention, screen use and mental health, parenting, youth well-being, and meditation and mindfulness. Rebecca's experience prior to Mashable includes working as a staff writer, reporter, and editor at NBC News Digital and as a staff writer at Forbes. Rebecca has a B.A. from Sarah Lawrence College and a masters degree from U.C. Berkeley's Graduate School of Journalism. [Read Full Bio](https://mashable.com/author/rebecca-ruiz) on April 12, 2026 [Share on Facebook](https://www.facebook.com/sharer.php?u=https%3A%2F%2Fmashable.com%2Farticle%2Fai-chatgpt-chatbot-claude-health-questions "(opens in a new window)") [Share on Twitter](https://twitter.com/intent/tweet?url=https%3A%2F%2Fmashable.com%2Farticle%2Fai-chatgpt-chatbot-claude-health-questions&text=Using+AI+for+health+questions%3F+Here+are+4+tips+for+the+most+accurate+answers. "(opens in a new window)") [Share on Flipboard](https://share.flipboard.com/bookmarklet/popout?v=2&url=https%3A%2F%2Fmashable.com%2Farticle%2Fai-chatgpt-chatbot-claude-health-questions&title=Using+AI+for+health+questions%3F+Here+are+4+tips+for+the+most+accurate+answers. "(opens in a new window)") ![A woman drinks a cup of coffee while asking an AI chatbot why she gets headaches at night. ](https://helios-i.mashable.com/imagery/articles/04DLwuExzhZpwIL5OOWZi6l/hero-image.fill.size_1248x702.v1773429984.jpg) Prompting an AI chatbot to talk about your health accurately may be trickier than you realize. Credit: Zooey Liao/Mashable/Getty Images *** Every day, millions of people turn to an [artificial intelligence](https://mashable.com/category/artificial-intelligence) chatbot like Claude, [Gemini](https://mashable.com/category/gemini), and [ChatGPT](https://mashable.com/category/chatgpt) to ask a question about their physical health. They may not know that getting the correct answer is harder than it appears, no matter how authoritatively the chatbot responds. Three recent studies indicate that large language models aren't as reliable as users may hope. SEE ALSO: [Read this before you use ChatGPT Health](https://mashable.com/article/chat-gpt-health-privacy-legal-concerns-experts-warn) One study that [tested chatbots' ability to detect health misinformation](https://www.sciencedirect.com/science/article/pii/S2589750025001311 "(opens in a new window)") failed more often than not in certain scenarios. Another study conducted by some of the same [researchers found that ChatGPT Health](https://www.nature.com/articles/s41591-026-04297-7 "(opens in a new window)"), a dedicated health and wellness service that debuted in January, "under-triaged" slightly more than half of cases presented to it, including emergency conditions that required immediate medical care. "I think that consumers should have a high degree of caution, like almost an abundance of caution," Dr. Girish N. Nadkarni, an internist and nephrologist at Mt. Sinai, who co-authored both of the studies, said of querying a chatbot for health advice. This may surprise users who hear that chatbots can easily pass a medical exam, even if they sometimes hallucinate outside of a testing environment. Yet the recent research points to a complex, somewhat hidden problem. The way humans interact with chatbots, and the manner in which they're designed to expertly please, creates unpredictability. Those factors are never a challenge for AI being tested on textbook medical questions. If you want to start, or continue using, a chatbot for your health questions, take these expert-recommended steps as you come up with prompts: ## 1\. Test the model with misinformation or inaccuracies first. Nadkarni, an AI health researcher and director of Mt. Sinai's Hasso Plattner Institute for Digital Health, says it's important to ask the chatbot about medical misinformation or known falsehoods prior to querying it about specific health questions. Challenge the chatbot, for example, to comment on a conspiracy theory about a vaccine, such as whether it agrees that the COVID-19 shot [contains a microchip to track people](https://mashable.com/video/covid-vaccine-myths-debunked-doctors). Or prompt it to respond to a slightly more challenging health controversy, like the [safety of fluoride in drinking water](https://www.everydayhealth.com/general-health/fluoride-in-drinking-water-is-it-safe/ "(opens in a new window)"). While researchers have found evidence that extremely high levels of fluoride can be dangerous, experts agree that [current standard levels remain safe](https://www.everydayhealth.com/general-health/fluoride-in-drinking-water-is-it-safe/ "(opens in a new window)"). Testing the chatbot with misinformation should provide a revealing baseline for the potential accuracy of its other responses, Nadkarni says. *** *A new Mashable series, AI + Health, will examine how artificial intelligence is changing the medical and health landscape. We'll explore how to use AI to [decipher your blood work](https://mashable.com/article/blood-test-ai-help-answers)**, how to [keep your health data safe](https://%20https://mashable.com/article/chat-gpt-health-privacy-legal-concerns)**, learn how [two women are using AI to detect a dangerous form of heart disease](https://%20https//mashable.com/article/ai-heart-disease-detect-sonorus-interview)**, and much more.* *** His recent study found that several general-purpose chatbots, including ChatGPT, inconsistently detected misinformation across many scenarios. Success rates depended on the context, like whether it was presented in a social media post versus a medical note. They also failed often when presented with specific logical fallacies. For example, when the prompt with misinformation appeared to come from a physician, via a real note drawn from an electronic health record, the chatbot was more likely to miss the falsehoods. If the chatbot you're consulting agrees with statements you know to be partially or wholly false, Nadkarni says avoid asking it for its opinion on your personal health questions. ## 2\. Consider the cues or information you may be giving the chatbot. When Nadkarni and his colleagues tested ChatGPT Health earlier this year, they discovered that how users frame their symptoms may influence the model's accuracy. If, for example, the prompt included statements about friends or family downplaying the symptoms in question, ChatGPT Health's recommendation shifted in that direction as well. In those instances, the chatbot was 11 times more likely not to send the patient to the emergency room, even when their symptoms indicated a life-threatening condition. The results were published as a [peer-reviewed advance paper in *Nature Medicine*](https://www.nature.com/articles/s41591-026-04297-7 "(opens in a new window)")*.* OpenAI objected to the results, arguing that the study methods didn't represent how people use ChatGPT over multiple chats, sharing information and answering follow-up questions. Karan Singhal, who leads the Health AI team at OpenAI, told Mashable in a statement that its own benchmarking indicates that GPT-5 models "correctly refer emergency cases nearly 99 percent of the time." Nadkarni said that while he welcomed debate, the criticism "missed the point." He said that while ChatGPT Health correctly identified abnormalities in the presented data, it reasoned past them. "The issue is not missing information but incorrect conclusions despite correct data," Nadkarni told Mashable. A separate recent study, also published in *Nature Medicine* but by a different group of researchers, randomly assigned 1,298 human participants to present a [predetermined medical scenario to an AI chatbot](https://www.nature.com/articles/s41591-025-04074-y.epdf?sharing_token=TUHXeeILFjwd_3R5HhgGRtRgN0jAjWel9jnR3ZoTv0PbRqAnGQQTDg7KCxy9aBjNNHLnwwMLoNiBmVen1cqdaaJjCGGFG8oJJNXiH0W5OGHBzBILL5_jhDjROPXT901WlpHrQZTwLWRh4ladS-iDkRwh1gfkCpRGFuXZ3nd1Dgc%3D "(opens in a new window)") (GPT-4o, Llama 3, and Command R+) or a source of their choice, including Google. When the chatbots were tested simply on the scenarios, they correctly identified the condition in nearly 95 percent of the cases. Once humans began posing questions about the scenario, however, the same chatbots could accurately pinpoint the condition in only about a third of cases. "Despite LLMs alone having high proficiency in the task, the combination of LLMs and human users was no better than the control group in assessing clinical acuity and worse at identifying relevant conditions," the researchers wrote. Many participants lacked an accurate understanding of the symptom severity, which contributed to the failure rate. SEE ALSO: [What AI can really say about your blood test](https://mashable.com/article/blood-test-ai-help-answers) ## 3\. Take into account whether you're a novice or expert. This is the kind of dynamic that [Dr. Robert Wachter](https://medicine.ucsf.edu/people/robert-wachter "(opens in a new window)") keeps in mind when he considers how people prompt a chatbot for answers to medical questions. Wachter, professor and chair of the Department of Medicine at the University of California, San Francisco, routinely uses OpenEvidence, an AI chatbot designed for physicians and healthcare professionals. He finds the AI's answers to complex medical questions largely fast, accurate, and helpful. Wachter, author of "[A Giant Leap: How AI is Transforming Healthcare and What That Means for Our Future](https://www.amazon.com/Giant-Leap-Transforming-Healthcare-Future/dp/B0F7G3216X "(opens in a new window)")," also believes that general-purpose and health-specific chatbots can be very useful to the average patient compared to a basic Google search. Yet he's also aware that he approaches AI chatbots as an expert with 40 years of medical experience and can quickly identify the most relevant details to include in a prompt. *** Related Stories *** - [3 things 'The Pitt' episode '8:00 AM' gets right about AI in medicine, and 1 big thing it gets wrong](https://mashable.com/article/the-pitt-season-2-artificial-intelligence) - [ChatGPT can now generate visuals for math and science lessons](https://mashable.com/article/chat-gpt-dynamic-visuals-interactive-learning) - [Experts: AI chatbots unsafe for teen mental health](https://mashable.com/article/chatgpt-claude-meta-ai-gemini-unsafe-for-teen-mental-health) - [OpenAI says ChatGPT-5 is a fast, 'active thought partner' for health issues](https://mashable.com/article/chatgpt-5-health-openai) "A patient has absolutely no ability to do that — to know what are the salient facts of all the things that might be going on in terms of their current symptoms, in terms of their past history, in terms of their medication," he says. "So what they put into the prompt may be not exactly right." Wachter says that recent research demonstrates a clear risk for patients when they don't know the right information to use in a prompt, and when they misinterpret the chatbot's response. Still, he believes that more often than not, an AI chatbot is better than nothing, provided patients focus on including relevant health history and current symptoms, and use it with a "buyer beware" attitude. In particular, Wachter says he wouldn't trust a chatbot for symptoms that may indicate a life-threatening emergency, such as severe chest pain, new shortness of breath or confusion, or weakness on one side of the body. ## 4\. Ask for references and cross-check the answer. When a chatbot gives its response, Nadkarni suggests taking the time to ask for its references for the information provided. It's not enough to scan a list of links, either. Nadkarni recommends clicking links to evaluate the source. If the chatbot has based its answer on a "shady Reddit post," Nadkarni says it's probably not trustworthy. On the other hand, if the reference directs you to a verifiable medical organization, like the American Medical Association, that should be reassuring. Nadkarni acknowledges that while individual users may not agree with the views of a health organization or authority, the information usually reflects medical consensus based on the best current evidence. Wachter also recommends asking a second AI chatbot that you trust to weigh in on the same health information you shared with the first chatbot to see if it arrives at the same conclusion. That can be a good indication that the response is useful and reliable. Despite Wachter's enthusiasm for AI chatbots in healthcare, he believes the recent studies indicate substantial room for improvement. He imagines AI tools that act more like a "good doctor," engaging the user in conversation to elicit all the relevant information before suggesting a diagnosis or action, like taking medication or going to the emergency room. "I think the patient-facing tools are not where they're going to end up," he says of present-day AI chatbots that field health questions. "Ultimately, the tool for a patient is going to be much more \[like a doctor\] than the tools now." \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ *The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.* *Disclosure: Ziff Davis, Mashable’s parent company, in April 2025 filed a lawsuit against OpenAI, alleging it infringed Ziff Davis copyrights in training and operating its AI systems.* Topics [Artificial Intelligence](https://mashable.com/category/artificial-intelligence) [Health](https://mashable.com/category/health) [Social Good](https://mashable.com/category/social-good) [ChatGPT](https://mashable.com/category/chatgpt) ![Rebecca Ruiz](https://helios-i.mashable.com/imagery/authors/01s9tVH6oSuivSFQB7tUAV3/image.fill.size_100x100.v1624381012.jpg) Rebecca Ruiz Senior Reporter Rebecca Ruiz is a Senior Reporter at Mashable. She frequently covers mental health, digital culture, and technology. Her areas of expertise include suicide prevention, screen use and mental health, parenting, youth well-being, and meditation and mindfulness. Rebecca's experience prior to Mashable includes working as a staff writer, reporter, and editor at NBC News Digital and as a staff writer at Forbes. Rebecca has a B.A. from Sarah Lawrence College and a masters degree from U.C. 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Every day, millions of people turn to an [artificial intelligence](https://mashable.com/category/artificial-intelligence) chatbot like Claude, [Gemini](https://mashable.com/category/gemini), and [ChatGPT](https://mashable.com/category/chatgpt) to ask a question about their physical health. They may not know that getting the correct answer is harder than it appears, no matter how authoritatively the chatbot responds. Three recent studies indicate that large language models aren't as reliable as users may hope. One study that [tested chatbots' ability to detect health misinformation](https://www.sciencedirect.com/science/article/pii/S2589750025001311 "(opens in a new window)") failed more often than not in certain scenarios. Another study conducted by some of the same [researchers found that ChatGPT Health](https://www.nature.com/articles/s41591-026-04297-7 "(opens in a new window)"), a dedicated health and wellness service that debuted in January, "under-triaged" slightly more than half of cases presented to it, including emergency conditions that required immediate medical care. "I think that consumers should have a high degree of caution, like almost an abundance of caution," Dr. Girish N. Nadkarni, an internist and nephrologist at Mt. Sinai, who co-authored both of the studies, said of querying a chatbot for health advice. This may surprise users who hear that chatbots can easily pass a medical exam, even if they sometimes hallucinate outside of a testing environment. Yet the recent research points to a complex, somewhat hidden problem. The way humans interact with chatbots, and the manner in which they're designed to expertly please, creates unpredictability. Those factors are never a challenge for AI being tested on textbook medical questions. If you want to start, or continue using, a chatbot for your health questions, take these expert-recommended steps as you come up with prompts: ## 1\. Test the model with misinformation or inaccuracies first. Nadkarni, an AI health researcher and director of Mt. Sinai's Hasso Plattner Institute for Digital Health, says it's important to ask the chatbot about medical misinformation or known falsehoods prior to querying it about specific health questions. Challenge the chatbot, for example, to comment on a conspiracy theory about a vaccine, such as whether it agrees that the COVID-19 shot [contains a microchip to track people](https://mashable.com/video/covid-vaccine-myths-debunked-doctors). Or prompt it to respond to a slightly more challenging health controversy, like the [safety of fluoride in drinking water](https://www.everydayhealth.com/general-health/fluoride-in-drinking-water-is-it-safe/ "(opens in a new window)"). While researchers have found evidence that extremely high levels of fluoride can be dangerous, experts agree that [current standard levels remain safe](https://www.everydayhealth.com/general-health/fluoride-in-drinking-water-is-it-safe/ "(opens in a new window)"). Testing the chatbot with misinformation should provide a revealing baseline for the potential accuracy of its other responses, Nadkarni says. *** *A new Mashable series, AI + Health, will examine how artificial intelligence is changing the medical and health landscape. We'll explore how to use AI to [decipher your blood work](https://mashable.com/article/blood-test-ai-help-answers)**, how to [keep your health data safe](https://%20https://mashable.com/article/chat-gpt-health-privacy-legal-concerns)**, learn how [two women are using AI to detect a dangerous form of heart disease](https://%20https//mashable.com/article/ai-heart-disease-detect-sonorus-interview)**, and much more.* *** His recent study found that several general-purpose chatbots, including ChatGPT, inconsistently detected misinformation across many scenarios. Success rates depended on the context, like whether it was presented in a social media post versus a medical note. They also failed often when presented with specific logical fallacies. For example, when the prompt with misinformation appeared to come from a physician, via a real note drawn from an electronic health record, the chatbot was more likely to miss the falsehoods. If the chatbot you're consulting agrees with statements you know to be partially or wholly false, Nadkarni says avoid asking it for its opinion on your personal health questions. ## 2\. Consider the cues or information you may be giving the chatbot. When Nadkarni and his colleagues tested ChatGPT Health earlier this year, they discovered that how users frame their symptoms may influence the model's accuracy. If, for example, the prompt included statements about friends or family downplaying the symptoms in question, ChatGPT Health's recommendation shifted in that direction as well. In those instances, the chatbot was 11 times more likely not to send the patient to the emergency room, even when their symptoms indicated a life-threatening condition. The results were published as a [peer-reviewed advance paper in *Nature Medicine*](https://www.nature.com/articles/s41591-026-04297-7 "(opens in a new window)")*.* OpenAI objected to the results, arguing that the study methods didn't represent how people use ChatGPT over multiple chats, sharing information and answering follow-up questions. Karan Singhal, who leads the Health AI team at OpenAI, told Mashable in a statement that its own benchmarking indicates that GPT-5 models "correctly refer emergency cases nearly 99 percent of the time." Nadkarni said that while he welcomed debate, the criticism "missed the point." He said that while ChatGPT Health correctly identified abnormalities in the presented data, it reasoned past them. "The issue is not missing information but incorrect conclusions despite correct data," Nadkarni told Mashable. A separate recent study, also published in *Nature Medicine* but by a different group of researchers, randomly assigned 1,298 human participants to present a [predetermined medical scenario to an AI chatbot](https://www.nature.com/articles/s41591-025-04074-y.epdf?sharing_token=TUHXeeILFjwd_3R5HhgGRtRgN0jAjWel9jnR3ZoTv0PbRqAnGQQTDg7KCxy9aBjNNHLnwwMLoNiBmVen1cqdaaJjCGGFG8oJJNXiH0W5OGHBzBILL5_jhDjROPXT901WlpHrQZTwLWRh4ladS-iDkRwh1gfkCpRGFuXZ3nd1Dgc%3D "(opens in a new window)") (GPT-4o, Llama 3, and Command R+) or a source of their choice, including Google. When the chatbots were tested simply on the scenarios, they correctly identified the condition in nearly 95 percent of the cases. Once humans began posing questions about the scenario, however, the same chatbots could accurately pinpoint the condition in only about a third of cases. "Despite LLMs alone having high proficiency in the task, the combination of LLMs and human users was no better than the control group in assessing clinical acuity and worse at identifying relevant conditions," the researchers wrote. Many participants lacked an accurate understanding of the symptom severity, which contributed to the failure rate. ## 3\. Take into account whether you're a novice or expert. This is the kind of dynamic that [Dr. Robert Wachter](https://medicine.ucsf.edu/people/robert-wachter "(opens in a new window)") keeps in mind when he considers how people prompt a chatbot for answers to medical questions. Wachter, professor and chair of the Department of Medicine at the University of California, San Francisco, routinely uses OpenEvidence, an AI chatbot designed for physicians and healthcare professionals. He finds the AI's answers to complex medical questions largely fast, accurate, and helpful. Wachter, author of "[A Giant Leap: How AI is Transforming Healthcare and What That Means for Our Future](https://www.amazon.com/Giant-Leap-Transforming-Healthcare-Future/dp/B0F7G3216X "(opens in a new window)")," also believes that general-purpose and health-specific chatbots can be very useful to the average patient compared to a basic Google search. Yet he's also aware that he approaches AI chatbots as an expert with 40 years of medical experience and can quickly identify the most relevant details to include in a prompt. "A patient has absolutely no ability to do that — to know what are the salient facts of all the things that might be going on in terms of their current symptoms, in terms of their past history, in terms of their medication," he says. "So what they put into the prompt may be not exactly right." Wachter says that recent research demonstrates a clear risk for patients when they don't know the right information to use in a prompt, and when they misinterpret the chatbot's response. Still, he believes that more often than not, an AI chatbot is better than nothing, provided patients focus on including relevant health history and current symptoms, and use it with a "buyer beware" attitude. In particular, Wachter says he wouldn't trust a chatbot for symptoms that may indicate a life-threatening emergency, such as severe chest pain, new shortness of breath or confusion, or weakness on one side of the body. ## 4\. Ask for references and cross-check the answer. When a chatbot gives its response, Nadkarni suggests taking the time to ask for its references for the information provided. It's not enough to scan a list of links, either. Nadkarni recommends clicking links to evaluate the source. If the chatbot has based its answer on a "shady Reddit post," Nadkarni says it's probably not trustworthy. On the other hand, if the reference directs you to a verifiable medical organization, like the American Medical Association, that should be reassuring. Nadkarni acknowledges that while individual users may not agree with the views of a health organization or authority, the information usually reflects medical consensus based on the best current evidence. Wachter also recommends asking a second AI chatbot that you trust to weigh in on the same health information you shared with the first chatbot to see if it arrives at the same conclusion. That can be a good indication that the response is useful and reliable. Despite Wachter's enthusiasm for AI chatbots in healthcare, he believes the recent studies indicate substantial room for improvement. He imagines AI tools that act more like a "good doctor," engaging the user in conversation to elicit all the relevant information before suggesting a diagnosis or action, like taking medication or going to the emergency room. "I think the patient-facing tools are not where they're going to end up," he says of present-day AI chatbots that field health questions. "Ultimately, the tool for a patient is going to be much more \[like a doctor\] than the tools now." \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ *The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.* *Disclosure: Ziff Davis, Mashable’s parent company, in April 2025 filed a lawsuit against OpenAI, alleging it infringed Ziff Davis copyrights in training and operating its AI systems.*
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