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| Meta Title | Long-term neuropsychiatric symptoms of COVID-19 among adults — Canada.ca |
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| Boilerpipe Text | Most people will experience and recover from initial symptoms of COVID-19 illness. Some will develop ongoing symptoms more than 3 months after their COVID-19 infection
Footnote
1
. Long-term symptoms of COVID-19 can be grouped into two major categories
Footnote
2
,
Footnote
3
:
cardiopulmonary - related to the heart and lungs
neuropsychiatric
- related to the nervous system, cognitive function (such as thinking, reasoning, memory, and judgement) and mental health
Neuropsychiatric symptoms are more common. Two-thirds of adults experiencing long-term symptoms of COVID-19 report neuropsychiatric symptoms.
For this survey, data on the following neuropsychiatric symptoms were collected:
difficulty thinking and solving problems (brain fog)
stress or anxiety
sadness, negativity, hopelessness, or depression
headache
loss of taste or smell
There are other long-term neuropsychiatric symptoms of COVID-19 not captured in the survey. These 5 are the most commonly reported symptoms.
Rate of long-term neuropsychiatric symptoms of COVID-19
More than 1 in 10 (11.3%, weighted count of 902,700) adults experienced long-term neuropsychiatric symptoms (Table 1).
Rate by socio-demographic group
We examined the rate of long-term neuropsychiatric symptoms across different socio-demographic groups.
Age
A similar percentage of adults across age groups reported long-term neuropsychiatric symptoms. People aged 50 to 64 had the highest rate (12.5%). Differences between age groups were not statistically significant (Table 1).
Sex
Females (14.5%) were 1.8 times more likely to report long-term neuropsychiatric symptoms than males (8.2%) (Table 1).
Ethnoracial group
The Indigenous identity group had the highest rate of long-term neuropsychiatric symptoms (21.2%) (Table 1). The rate was:
1.8 times higher than the Non-racialized group (11.9%)
2.5 times higher than the Racialized group (8.4%)
Table 1. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by socio-demographic characteristics.
Table 1. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by socio-demographic characteristics.
Characteristic
Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%)
95% Confidence interval (CI)
Weighted count ** (n)
Overall rate
11.3
10.3-12.4
902,700
Age (years)
18-34
11.1
9.1-13.1
326,500
35-49
10.9
9.2-12.7
270,400
50-64
12.5
10.4-14.5
226,500
65+
10.8
8.0-13.6
79,200
Sex
Female
14.5
12.9-16.1
576,800
Male
8.2
6.8-9.6
325,900
Ethnoracial group
Indigenous identity group
21.2
13.7-28.7
57,200
Non-racialized group
§
11.9
10.7-13.2
667,200
Racialized group
ÂĄ
8.4
6.2-10.6
175,900
§
Non-racialized group- all respondents who identified as White, excluding those who identified as Indigenous
ÂĄ
Racialized group- all respondents who did not identify as Indigenous or White
** Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
Among adults with a history of mental health condition or chronic neurological disorder
Adults were more likely to report long-term neuropsychiatric symptoms if they had a history of:
mental health condition (e.g., depression, anxiety)
chronic neurological disorder (e.g., Alzheimer's disease or other dementia, and other neurological conditions)
The percentage reporting long-term neuropsychiatric symptoms was:
2.0 times higher among those with a history of mental health condition (20.3%) than those without a history (10.2%)
2.4 times higher among those with a history of chronic neurological disorder (26.3%
E
) than those without a history (11.1%) (Table 2)
Table 2. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by history of mental health condition or chronic neurological disorder.
Table 2. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by history of mental health condition or chronic neurological disorder.
Having a history of
Response
Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%)
95% Confidence Interval (CI)
Weighted count** (n)
Mental health condition
Yes
20.3
16.4-24.6
183,000
No
10.2
9.1-11.4
719,700
Chronic neurological disorder
Yes
26.3
E
14.7-41.0
E
31,500
No
11.1
10.1-12.2
871,200
** Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
E
Results should be interpreted with caution due to high sampling variability.
Among adults with difficulties accessing healthcare
The survey asked respondents if they had difficulties accessing healthcare services in the last 12 months. Across most categories, adults who experienced difficulties were more likely to report long-term neuropsychiatric symptoms (Table 3).
The percentage reporting long-term neuropsychiatric symptoms was 2.2 times higher among those who had any difficulty accessing healthcare services (17.0%) than those who did not (7.6%) (Table 3).
The most common difficulties were:
lack of availability of culturally appropriate health services (25.3%
E
)
cost issues (23.1%
E
)
transportation issues (23.0%
E
)
unavailability of healthcare services in the residential area (22.4%)
Table 3. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by difficulties accessing healthcare services.
Table 3. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by difficulties accessing healthcare services.
Difficulties accessing healthcare services
Response
Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%)
95% Confidence Interval (CI)
Weighted count** (n)
Any difficulty
Yes
17.0
15.0-19.1
537,800
No
7.6
6.5-8.8
364,900
Lack of availability of culturally appropriate health services
Yes
25.3
E
11.2-44.7
E
18,800
No
11.4
10.3-12.5
863,100
Cost issues
Yes
23.1
E
16.3-31.2
E
89,900
No
10.9
9.8-12.0
792,000
Transportation issues
Yes
23.0
E
13.1-35.6
E
31,300
No
11.3
10.2-12.4
850,600
Not available in my area
Yes
22.4
16.5-29.3
92,000
No
10.9
9.8-12.0
789,900
Quarantine or office closures
Yes
21.0
16.7-25.9
191,500
No
10.2
9.2-11.3
690,300
Appointment cancellation, delay or rescheduling due to non-COVID-19 pandemic reasons
Yes
20.3
14.8-26.8
117,000
No
10.8
9.7-11.9
764,800
Appointment cancellation, delay or rescheduling due to COVID-19 pandemic
Yes
19.3
16.0-22.9
285,500
No
9.6
8.5-10.8
596,300
Waited too long between booking appointments and services
Yes
18.0
14.9-21.4
252,400
No
10.0
8.9-11.2
629,500
Difficulty getting a referral
Yes
16.3
12.6-20.6
134,500
No
10.9
9.8-12.1
747,400
** Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
E
Results should be interpreted with caution due to high sampling variability.
Severity of COVID-19 symptoms
Adults with more severe initial COVID-19 symptoms were more likely to have long-term neuropsychiatric symptoms (Table 4). The percentage of those who had long-term neuropsychiatric symptoms was:
27.8% among those who reported severe COVID-19 symptoms
11.5% among those who reported moderate COVID-19 symptoms
4.4% among those who reported mild COVID-19 symptoms
Table 4. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by severity of initial COVID-19 symptoms.
Table 4. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by severity of initial COVID-19 symptoms.
Impact of COVID-19
Response
Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%)
95% Confidence Interval (CI)
Weighted count** (n)
Severity of initial COVID-19 symptoms
Mild symptoms- no effect on daily life
4.4
3.3-5.7
114,000
Moderate symptoms- some effect on daily life
11.5
9.8-13.3
391,100
Severe symptoms- significant effect on daily life
27.8
24.3-31.6
386,400
** Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
Subset population with neuropsychiatric symptoms
The data below come from the subset of people who experienced neuropsychiatric symptoms of COVID-19. This is different from other data in this blog, which come from the larger group of people with a COVID-19 infection 3 or more months prior to the survey.
Limitations to daily activities from COVID-19 symptoms
The survey asked about limitations to daily activities from COVID-19 symptoms. 1 in 4 (23.8%) adults with long-term neuropsychiatric symptoms were often or always limited in daily activities by their symptoms (Table 5).
Accessing healthcare for COVID-19 symptoms
Some respondents reported difficulty accessing healthcare (Table 3). These respondents were also asked about accessing healthcare services for COVID-19 symptoms. 4 in 10 (39.8%) adults with long-term neuropsychiatric symptoms reported experiencing difficulties (Table 5).
Table 5. Percentage of adults with long-term neuropsychiatric symptoms of COVID-19 reporting limitations to daily activities due to COVID-19 symptoms and difficulties accessing healthcare for COVID-19 symptoms in the last 12 months.
Table 5. Percentage of adults with long-term neuropsychiatric symptoms of COVID-19 reporting limitations to daily activities due to COVID-19 symptoms and difficulties accessing healthcare for COVID-19 symptoms in the last 12 months.
Impact of COVID-19
Response
Percentage (%)
95% Confidence Interval (CI)
Weighted Count** (n)
Limitations to daily activities due to COVID-19 symptoms
Never
13.2
9.9-17.0
118,800
Rarely or sometimes
6.7
57.7-67.6
566,300
Often or always
23.8
19.8-28.2
215,100
Difficulties accessing healthcare services for COVID-19 symptoms in the last 12 months
Yes
39.8
33.4-46.9
213,700
No
60.2
53.6-66.6
323,600
** Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
On May 5, 2023, the World Health Organization declared that COVID-19 is an established and ongoing health issue that no longer constitutes a global health threat. While it is no longer classified as a public health emergency, many people living in Canada continue to be affected by COVID-19. If you or someone close to you is experiencing long-term symptoms of COVID-19, including neuropsychiatric symptoms, it is important to talk to a health care provider.
For more information on long-term symptoms of COVID-19
Post-COVID-19 condition (long COVID)
COVID-19 longer-term symptoms among Canadian adults
COVID-19 epidemiology update: Summary
About the data
This blog uses national data from the
Canadian COVID-19 Antibody and Health Survey (CCAHS) – Cycle 2
, collected by Statistics Canada. The survey collected information between April and August 2022. Data is from adults 18 years and older living in Canada. Unless otherwise noted, data is from adults who self-reported a COVID-19 infection 3 or more months before the survey. COVID-19 infections could be confirmed by a test or suspected from experienced symptoms or known exposures.
A weight was assigned to each respondent of the survey, so the results accurately represent the Canadian population. A
weighted count
uses these assigned weights and is not the actual number of survey respondents.
Populations excluded from the CCAHS-2 were people:
living in the three territories
less than 18 years old
living on reserves and other Indigenous settlements in the provinces
living in institutions
full-time members of the Canadian Forces living on base
residents in certain remote regions
For more information on the CCAHS-2, visit
Canadian COVID-19 Antibody and Health Survey (CCAHS)-Cycle 2
.
Suggested citation
Long-term neuropsychiatric symptoms of COVID-19 among adults. Data from the Canadian COVID-19 Antibody and Health Survey – Cycle 2 April to August 2022. Public Health Agency of Canada, Centre for Surveillance and Applied Research. 2024.
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2024-10-30 |
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# Long-term neuropsychiatric symptoms of COVID-19 among adults:Data blog
Data from the Canadian COVID-19 Antibody and Health Survey - Cycle 2 April to August 2022.
- Last updated: 2024-10-30

Most people will experience and recover from initial symptoms of COVID-19 illness. Some will develop ongoing symptoms more than 3 months after their COVID-19 infection[Footnote 1](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn1 "Post-COVID-19 condition. Annual Review of Medicine."). Long-term symptoms of COVID-19 can be grouped into two major categories[Footnote2](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn2 "Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients. The Lancet Psychiatry. 2022 Oct 1;9(10):815-27."),[Footnote 3](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn3 "Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness. The Lancet Respiratory Medicine. 2023 Aug 1;11(8):726-38."):
- cardiopulmonary - related to the heart and lungs
- **neuropsychiatric** - related to the nervous system, cognitive function (such as thinking, reasoning, memory, and judgement) and mental health
Neuropsychiatric symptoms are more common. Two-thirds of adults experiencing long-term symptoms of COVID-19 report neuropsychiatric symptoms.
***

## About long-term neuropsychiatric symptoms of COVID-19
For this survey, data on the following neuropsychiatric symptoms were collected:
- difficulty thinking and solving problems (brain fog)
- stress or anxiety
- sadness, negativity, hopelessness, or depression
- headache
- loss of taste or smell
There are other long-term neuropsychiatric symptoms of COVID-19 not captured in the survey. These 5 are the most commonly reported symptoms.
***

## Rate of long-term neuropsychiatric symptoms of COVID-19
More than 1 in 10 (11.3%, weighted count of 902,700) adults experienced long-term neuropsychiatric symptoms (Table 1).
### Rate by socio-demographic group
We examined the rate of long-term neuropsychiatric symptoms across different socio-demographic groups.
#### Age
A similar percentage of adults across age groups reported long-term neuropsychiatric symptoms. People aged 50 to 64 had the highest rate (12.5%). Differences between age groups were not statistically significant (Table 1).
#### Sex
Females (14.5%) were 1.8 times more likely to report long-term neuropsychiatric symptoms than males (8.2%) (Table 1).
#### Ethnoracial group
The Indigenous identity group had the highest rate of long-term neuropsychiatric symptoms (21.2%) (Table 1). The rate was:
- 1\.8 times higher than the Non-racialized group (11.9%)
- 2\.5 times higher than the Racialized group (8.4%)
Table 1. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by socio-demographic characteristics.
| Characteristic | Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%) | 95% Confidence interval (CI) | Weighted count \*\* (n) | |
|---|---|---|---|---|
| **Overall rate** | 11\.3 | 10\.3-12.4 | 902,700 | |
| Age (years) | 18-34 | 11\.1 | 9\.1-13.1 | 326,500 |
| 35-49 | 10\.9 | 9\.2-12.7 | 270,400 | |
| 50-64 | 12\.5 | 10\.4-14.5 | 226,500 | |
| 65+ | 10\.8 | 8\.0-13.6 | 79,200 | |
| Sex | Female | 14\.5 | 12\.9-16.1 | 576,800 |
| Male | 8\.2 | 6\.8-9.6 | 325,900 | |
| Ethnoracial group | Indigenous identity group | 21\.2 | 13\.7-28.7 | 57,200 |
| Non-racialized group§ | 11\.9 | 10\.7-13.2 | 667,200 | |
| Racialized groupÂĄ | 8\.4 | 6\.2-10.6 | 175,900 | |
§ Non-racialized group- all respondents who identified as White, excluding those who identified as Indigenous
ÂĄ Racialized group- all respondents who did not identify as Indigenous or White
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
***

## Among adults with a history of mental health condition or chronic neurological disorder
Adults were more likely to report long-term neuropsychiatric symptoms if they had a history of:
- mental health condition (e.g., depression, anxiety)
- chronic neurological disorder (e.g., Alzheimer's disease or other dementia, and other neurological conditions)
The percentage reporting long-term neuropsychiatric symptoms was:
- 2\.0 times higher among those with a history of mental health condition (20.3%) than those without a history (10.2%)
- 2\.4 times higher among those with a history of chronic neurological disorder (26.3%E) than those without a history (11.1%) (Table 2)
Table 2. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by history of mental health condition or chronic neurological disorder.
| Having a history of | Response | Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%) | 95% Confidence Interval (CI) | Weighted count\*\* (n) |
|---|---|---|---|---|
| Mental health condition | Yes | 20\.3 | 16\.4-24.6 | 183,000 |
| No | 10\.2 | 9\.1-11.4 | 719,700 | |
| Chronic neurological disorder | Yes | 26\.3E | 14\.7-41.0E | 31,500 |
| No | 11\.1 | 10\.1-12.2 | 871,200 | |
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
E Results should be interpreted with caution due to high sampling variability.
***

## Among adults with difficulties accessing healthcare
The survey asked respondents if they had difficulties accessing healthcare services in the last 12 months. Across most categories, adults who experienced difficulties were more likely to report long-term neuropsychiatric symptoms (Table 3).
The percentage reporting long-term neuropsychiatric symptoms was 2.2 times higher among those who had any difficulty accessing healthcare services (17.0%) than those who did not (7.6%) (Table 3).
The most common difficulties were:
- lack of availability of culturally appropriate health services (25.3%E)
- cost issues (23.1%E)
- transportation issues (23.0%E)
- unavailability of healthcare services in the residential area (22.4%)
Table 3. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by difficulties accessing healthcare services.
| Difficulties accessing healthcare services | Response | Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%) | 95% Confidence Interval (CI) | Weighted count\*\* (n) |
|---|---|---|---|---|
| Any difficulty | Yes | 17\.0 | 15\.0-19.1 | 537,800 |
| No | 7\.6 | 6\.5-8.8 | 364,900 | |
| Lack of availability of culturally appropriate health services | Yes | 25\.3E | 11\.2-44.7E | 18,800 |
| No | 11\.4 | 10\.3-12.5 | 863,100 | |
| Cost issues | Yes | 23\.1E | 16\.3-31.2E | 89,900 |
| No | 10\.9 | 9\.8-12.0 | 792,000 | |
| Transportation issues | Yes | 23\.0E | 13\.1-35.6E | 31,300 |
| No | 11\.3 | 10\.2-12.4 | 850,600 | |
| Not available in my area | Yes | 22\.4 | 16\.5-29.3 | 92,000 |
| No | 10\.9 | 9\.8-12.0 | 789,900 | |
| Quarantine or office closures | Yes | 21\.0 | 16\.7-25.9 | 191,500 |
| No | 10\.2 | 9\.2-11.3 | 690,300 | |
| Appointment cancellation, delay or rescheduling due to non-COVID-19 pandemic reasons | Yes | 20\.3 | 14\.8-26.8 | 117,000 |
| No | 10\.8 | 9\.7-11.9 | 764,800 | |
| Appointment cancellation, delay or rescheduling due to COVID-19 pandemic | Yes | 19\.3 | 16\.0-22.9 | 285,500 |
| No | 9\.6 | 8\.5-10.8 | 596,300 | |
| Waited too long between booking appointments and services | Yes | 18\.0 | 14\.9-21.4 | 252,400 |
| No | 10\.0 | 8\.9-11.2 | 629,500 | |
| Difficulty getting a referral | Yes | 16\.3 | 12\.6-20.6 | 134,500 |
| No | 10\.9 | 9\.8-12.1 | 747,400 | |
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
E Results should be interpreted with caution due to high sampling variability.
***

## Severity of COVID-19 symptoms
Adults with more severe initial COVID-19 symptoms were more likely to have long-term neuropsychiatric symptoms (Table 4). The percentage of those who had long-term neuropsychiatric symptoms was:
- 27\.8% among those who reported severe COVID-19 symptoms
- 11\.5% among those who reported moderate COVID-19 symptoms
- 4\.4% among those who reported mild COVID-19 symptoms
Table 4. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by severity of initial COVID-19 symptoms.
| Impact of COVID-19 | Response | Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%) | 95% Confidence Interval (CI) | Weighted count\*\* (n) |
|---|---|---|---|---|
| Severity of initial COVID-19 symptoms | Mild symptoms- no effect on daily life | 4\.4 | 3\.3-5.7 | 114,000 |
| Moderate symptoms- some effect on daily life | 11\.5 | 9\.8-13.3 | 391,100 | |
| Severe symptoms- significant effect on daily life | 27\.8 | 24\.3-31.6 | 386,400 | |
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
***

## Subset population with neuropsychiatric symptoms
The data below come from the subset of people who experienced neuropsychiatric symptoms of COVID-19. This is different from other data in this blog, which come from the larger group of people with a COVID-19 infection 3 or more months prior to the survey.
### Limitations to daily activities from COVID-19 symptoms
The survey asked about limitations to daily activities from COVID-19 symptoms. 1 in 4 (23.8%) adults with long-term neuropsychiatric symptoms were often or always limited in daily activities by their symptoms (Table 5).
### Accessing healthcare for COVID-19 symptoms
Some respondents reported difficulty accessing healthcare (Table 3). These respondents were also asked about accessing healthcare services for COVID-19 symptoms. 4 in 10 (39.8%) adults with long-term neuropsychiatric symptoms reported experiencing difficulties (Table 5).
Table 5. Percentage of adults with long-term neuropsychiatric symptoms of COVID-19 reporting limitations to daily activities due to COVID-19 symptoms and difficulties accessing healthcare for COVID-19 symptoms in the last 12 months.
| Impact of COVID-19 | Response | Percentage (%) | 95% Confidence Interval (CI) | Weighted Count\*\* (n) |
|---|---|---|---|---|
| Limitations to daily activities due to COVID-19 symptoms | Never | 13\.2 | 9\.9-17.0 | 118,800 |
| Rarely or sometimes | 6\.7 | 57\.7-67.6 | 566,300 | |
| Often or always | 23\.8 | 19\.8-28.2 | 215,100 | |
| Difficulties accessing healthcare services for COVID-19 symptoms in the last 12 months | Yes | 39\.8 | 33\.4-46.9 | 213,700 |
| No | 60\.2 | 53\.6-66.6 | 323,600 | |
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
***

On May 5, 2023, the World Health Organization declared that COVID-19 is an established and ongoing health issue that no longer constitutes a global health threat. While it is no longer classified as a public health emergency, many people living in Canada continue to be affected by COVID-19. If you or someone close to you is experiencing long-term symptoms of COVID-19, including neuropsychiatric symptoms, it is important to talk to a health care provider.
## For more information on long-term symptoms of COVID-19
- [Post-COVID-19 condition (long COVID)](https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/symptoms/post-covid-19-condition.html)
- [COVID-19 longer-term symptoms among Canadian adults](https://health-infobase.canada.ca/covid-19/post-covid-condition/)
- [COVID-19 epidemiology update: Summary](https://health-infobase.canada.ca/covid-19/)
## About the data
This blog uses national data from the [Canadian COVID-19 Antibody and Health Survey (CCAHS) – Cycle 2](https://www.statcan.gc.ca/en/survey/household/5339), collected by Statistics Canada. The survey collected information between April and August 2022. Data is from adults 18 years and older living in Canada. Unless otherwise noted, data is from adults who self-reported a COVID-19 infection 3 or more months before the survey. COVID-19 infections could be confirmed by a test or suspected from experienced symptoms or known exposures.
A weight was assigned to each respondent of the survey, so the results accurately represent the Canadian population. A **weighted count** uses these assigned weights and is not the actual number of survey respondents.
Populations excluded from the CCAHS-2 were people:
- living in the three territories
- less than 18 years old
- living on reserves and other Indigenous settlements in the provinces
- living in institutions
- full-time members of the Canadian Forces living on base
- residents in certain remote regions
For more information on the CCAHS-2, visit [Canadian COVID-19 Antibody and Health Survey (CCAHS)-Cycle 2](https://www.statcan.gc.ca/en/survey/household/5339).
### Suggested citation
Long-term neuropsychiatric symptoms of COVID-19 among adults. Data from the Canadian COVID-19 Antibody and Health Survey – Cycle 2 April to August 2022. Public Health Agency of Canada, Centre for Surveillance and Applied Research. 2024.
## References
Reference 1
Nalbandian A, Desai AD, Wan EY. Post-COVID-19 condition. Annual Review of Medicine. 2023 Jan 27; 74: 55-64.
[Return to footnote 1 referrer](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn1-rf)
Reference 2
Taquet M, Sillett R, Zhu L, Mendel J, Camplisson I, Dercon Q, Harrison PJ. Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients. The Lancet Psychiatry. 2022 Oct 1;9(10):815-27.
[Return to first footnote 2 referrer](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn2-rf)
Reference 3
Pandharipande P, Roberson SW, Harrison FE, Wilson JE, Bastarache JA, Ely EW. Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness. The Lancet Respiratory Medicine. 2023 Aug 1;11(8):726-38.
[Return to first footnote 3 referrer](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn3-rf)
***
## You might also be interested in

### [COVID-19: Longer-term symptoms among Canadian adults](https://health-infobase.canada.ca/covid-19/post-covid-condition/)
Data on longer-term symptoms of COVID-19 in Canada.

### [COVID-19 epidemiology update: Summary](https://health-infobase.canada.ca/covid-19/)
Summary of COVID-19 cases, hospitalizations and deaths, testing and variants of concern, and outbreaks across Canada.
[All Health Infobase data products](https://health-infobase.canada.ca/)
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Date modified:
2024-10-30
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| Readable Markdown | 
Most people will experience and recover from initial symptoms of COVID-19 illness. Some will develop ongoing symptoms more than 3 months after their COVID-19 infection[Footnote 1](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn1 "Post-COVID-19 condition. Annual Review of Medicine."). Long-term symptoms of COVID-19 can be grouped into two major categories[Footnote2](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn2 "Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients. The Lancet Psychiatry. 2022 Oct 1;9(10):815-27."),[Footnote 3](https://health-infobase.canada.ca/datalab/post-covid-condition-neuropsychiatric-symptoms.html#fn3 "Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness. The Lancet Respiratory Medicine. 2023 Aug 1;11(8):726-38."):
- cardiopulmonary - related to the heart and lungs
- **neuropsychiatric** - related to the nervous system, cognitive function (such as thinking, reasoning, memory, and judgement) and mental health
Neuropsychiatric symptoms are more common. Two-thirds of adults experiencing long-term symptoms of COVID-19 report neuropsychiatric symptoms.
***

For this survey, data on the following neuropsychiatric symptoms were collected:
- difficulty thinking and solving problems (brain fog)
- stress or anxiety
- sadness, negativity, hopelessness, or depression
- headache
- loss of taste or smell
There are other long-term neuropsychiatric symptoms of COVID-19 not captured in the survey. These 5 are the most commonly reported symptoms.
***

## Rate of long-term neuropsychiatric symptoms of COVID-19
More than 1 in 10 (11.3%, weighted count of 902,700) adults experienced long-term neuropsychiatric symptoms (Table 1).
### Rate by socio-demographic group
We examined the rate of long-term neuropsychiatric symptoms across different socio-demographic groups.
#### Age
A similar percentage of adults across age groups reported long-term neuropsychiatric symptoms. People aged 50 to 64 had the highest rate (12.5%). Differences between age groups were not statistically significant (Table 1).
#### Sex
Females (14.5%) were 1.8 times more likely to report long-term neuropsychiatric symptoms than males (8.2%) (Table 1).
#### Ethnoracial group
The Indigenous identity group had the highest rate of long-term neuropsychiatric symptoms (21.2%) (Table 1). The rate was:
- 1\.8 times higher than the Non-racialized group (11.9%)
- 2\.5 times higher than the Racialized group (8.4%)
Table 1. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by socio-demographic characteristics.
| Characteristic | Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%) | 95% Confidence interval (CI) | Weighted count \*\* (n) | |
|---|---|---|---|---|
| **Overall rate** | 11\.3 | 10\.3-12.4 | 902,700 | |
| Age (years) | 18-34 | 11\.1 | 9\.1-13.1 | 326,500 |
| 35-49 | 10\.9 | 9\.2-12.7 | 270,400 | |
| 50-64 | 12\.5 | 10\.4-14.5 | 226,500 | |
| 65+ | 10\.8 | 8\.0-13.6 | 79,200 | |
| Sex | Female | 14\.5 | 12\.9-16.1 | 576,800 |
| Male | 8\.2 | 6\.8-9.6 | 325,900 | |
| Ethnoracial group | Indigenous identity group | 21\.2 | 13\.7-28.7 | 57,200 |
| Non-racialized group§ | 11\.9 | 10\.7-13.2 | 667,200 | |
| Racialized groupÂĄ | 8\.4 | 6\.2-10.6 | 175,900 | |
§ Non-racialized group- all respondents who identified as White, excluding those who identified as Indigenous
ÂĄ Racialized group- all respondents who did not identify as Indigenous or White
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
***

## Among adults with a history of mental health condition or chronic neurological disorder
Adults were more likely to report long-term neuropsychiatric symptoms if they had a history of:
- mental health condition (e.g., depression, anxiety)
- chronic neurological disorder (e.g., Alzheimer's disease or other dementia, and other neurological conditions)
The percentage reporting long-term neuropsychiatric symptoms was:
- 2\.0 times higher among those with a history of mental health condition (20.3%) than those without a history (10.2%)
- 2\.4 times higher among those with a history of chronic neurological disorder (26.3%E) than those without a history (11.1%) (Table 2)
Table 2. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by history of mental health condition or chronic neurological disorder.
| Having a history of | Response | Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%) | 95% Confidence Interval (CI) | Weighted count\*\* (n) |
|---|---|---|---|---|
| Mental health condition | Yes | 20\.3 | 16\.4-24.6 | 183,000 |
| No | 10\.2 | 9\.1-11.4 | 719,700 | |
| Chronic neurological disorder | Yes | 26\.3E | 14\.7-41.0E | 31,500 |
| No | 11\.1 | 10\.1-12.2 | 871,200 | |
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
E Results should be interpreted with caution due to high sampling variability.
***

## Among adults with difficulties accessing healthcare
The survey asked respondents if they had difficulties accessing healthcare services in the last 12 months. Across most categories, adults who experienced difficulties were more likely to report long-term neuropsychiatric symptoms (Table 3).
The percentage reporting long-term neuropsychiatric symptoms was 2.2 times higher among those who had any difficulty accessing healthcare services (17.0%) than those who did not (7.6%) (Table 3).
The most common difficulties were:
- lack of availability of culturally appropriate health services (25.3%E)
- cost issues (23.1%E)
- transportation issues (23.0%E)
- unavailability of healthcare services in the residential area (22.4%)
Table 3. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by difficulties accessing healthcare services.
| Difficulties accessing healthcare services | Response | Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%) | 95% Confidence Interval (CI) | Weighted count\*\* (n) |
|---|---|---|---|---|
| Any difficulty | Yes | 17\.0 | 15\.0-19.1 | 537,800 |
| No | 7\.6 | 6\.5-8.8 | 364,900 | |
| Lack of availability of culturally appropriate health services | Yes | 25\.3E | 11\.2-44.7E | 18,800 |
| No | 11\.4 | 10\.3-12.5 | 863,100 | |
| Cost issues | Yes | 23\.1E | 16\.3-31.2E | 89,900 |
| No | 10\.9 | 9\.8-12.0 | 792,000 | |
| Transportation issues | Yes | 23\.0E | 13\.1-35.6E | 31,300 |
| No | 11\.3 | 10\.2-12.4 | 850,600 | |
| Not available in my area | Yes | 22\.4 | 16\.5-29.3 | 92,000 |
| No | 10\.9 | 9\.8-12.0 | 789,900 | |
| Quarantine or office closures | Yes | 21\.0 | 16\.7-25.9 | 191,500 |
| No | 10\.2 | 9\.2-11.3 | 690,300 | |
| Appointment cancellation, delay or rescheduling due to non-COVID-19 pandemic reasons | Yes | 20\.3 | 14\.8-26.8 | 117,000 |
| No | 10\.8 | 9\.7-11.9 | 764,800 | |
| Appointment cancellation, delay or rescheduling due to COVID-19 pandemic | Yes | 19\.3 | 16\.0-22.9 | 285,500 |
| No | 9\.6 | 8\.5-10.8 | 596,300 | |
| Waited too long between booking appointments and services | Yes | 18\.0 | 14\.9-21.4 | 252,400 |
| No | 10\.0 | 8\.9-11.2 | 629,500 | |
| Difficulty getting a referral | Yes | 16\.3 | 12\.6-20.6 | 134,500 |
| No | 10\.9 | 9\.8-12.1 | 747,400 | |
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
E Results should be interpreted with caution due to high sampling variability.
***

## Severity of COVID-19 symptoms
Adults with more severe initial COVID-19 symptoms were more likely to have long-term neuropsychiatric symptoms (Table 4). The percentage of those who had long-term neuropsychiatric symptoms was:
- 27\.8% among those who reported severe COVID-19 symptoms
- 11\.5% among those who reported moderate COVID-19 symptoms
- 4\.4% among those who reported mild COVID-19 symptoms
Table 4. Percentage reporting long-term neuropsychiatric symptoms of COVID-19 among adults who self-reported a suspected or confirmed COVID-19 infection 3 or more months prior to the survey, by severity of initial COVID-19 symptoms.
| Impact of COVID-19 | Response | Percentage reporting long-term neuropsychiatric symptoms of COVID-19 (%) | 95% Confidence Interval (CI) | Weighted count\*\* (n) |
|---|---|---|---|---|
| Severity of initial COVID-19 symptoms | Mild symptoms- no effect on daily life | 4\.4 | 3\.3-5.7 | 114,000 |
| Moderate symptoms- some effect on daily life | 11\.5 | 9\.8-13.3 | 391,100 | |
| Severe symptoms- significant effect on daily life | 27\.8 | 24\.3-31.6 | 386,400 | |
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
***

## Subset population with neuropsychiatric symptoms
The data below come from the subset of people who experienced neuropsychiatric symptoms of COVID-19. This is different from other data in this blog, which come from the larger group of people with a COVID-19 infection 3 or more months prior to the survey.
### Limitations to daily activities from COVID-19 symptoms
The survey asked about limitations to daily activities from COVID-19 symptoms. 1 in 4 (23.8%) adults with long-term neuropsychiatric symptoms were often or always limited in daily activities by their symptoms (Table 5).
### Accessing healthcare for COVID-19 symptoms
Some respondents reported difficulty accessing healthcare (Table 3). These respondents were also asked about accessing healthcare services for COVID-19 symptoms. 4 in 10 (39.8%) adults with long-term neuropsychiatric symptoms reported experiencing difficulties (Table 5).
Table 5. Percentage of adults with long-term neuropsychiatric symptoms of COVID-19 reporting limitations to daily activities due to COVID-19 symptoms and difficulties accessing healthcare for COVID-19 symptoms in the last 12 months.
| Impact of COVID-19 | Response | Percentage (%) | 95% Confidence Interval (CI) | Weighted Count\*\* (n) |
|---|---|---|---|---|
| Limitations to daily activities due to COVID-19 symptoms | Never | 13\.2 | 9\.9-17.0 | 118,800 |
| Rarely or sometimes | 6\.7 | 57\.7-67.6 | 566,300 | |
| Often or always | 23\.8 | 19\.8-28.2 | 215,100 | |
| Difficulties accessing healthcare services for COVID-19 symptoms in the last 12 months | Yes | 39\.8 | 33\.4-46.9 | 213,700 |
| No | 60\.2 | 53\.6-66.6 | 323,600 | |
\*\* Each respondent of the survey was assigned a weight to ensure that results accurately represent the overall population.
***

On May 5, 2023, the World Health Organization declared that COVID-19 is an established and ongoing health issue that no longer constitutes a global health threat. While it is no longer classified as a public health emergency, many people living in Canada continue to be affected by COVID-19. If you or someone close to you is experiencing long-term symptoms of COVID-19, including neuropsychiatric symptoms, it is important to talk to a health care provider.
## For more information on long-term symptoms of COVID-19
- [Post-COVID-19 condition (long COVID)](https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/symptoms/post-covid-19-condition.html)
- [COVID-19 longer-term symptoms among Canadian adults](https://health-infobase.canada.ca/covid-19/post-covid-condition/)
- [COVID-19 epidemiology update: Summary](https://health-infobase.canada.ca/covid-19/)
## About the data
This blog uses national data from the [Canadian COVID-19 Antibody and Health Survey (CCAHS) – Cycle 2](https://www.statcan.gc.ca/en/survey/household/5339), collected by Statistics Canada. The survey collected information between April and August 2022. Data is from adults 18 years and older living in Canada. Unless otherwise noted, data is from adults who self-reported a COVID-19 infection 3 or more months before the survey. COVID-19 infections could be confirmed by a test or suspected from experienced symptoms or known exposures.
A weight was assigned to each respondent of the survey, so the results accurately represent the Canadian population. A **weighted count** uses these assigned weights and is not the actual number of survey respondents.
Populations excluded from the CCAHS-2 were people:
- living in the three territories
- less than 18 years old
- living on reserves and other Indigenous settlements in the provinces
- living in institutions
- full-time members of the Canadian Forces living on base
- residents in certain remote regions
For more information on the CCAHS-2, visit [Canadian COVID-19 Antibody and Health Survey (CCAHS)-Cycle 2](https://www.statcan.gc.ca/en/survey/household/5339).
### Suggested citation
Long-term neuropsychiatric symptoms of COVID-19 among adults. Data from the Canadian COVID-19 Antibody and Health Survey – Cycle 2 April to August 2022. Public Health Agency of Canada, Centre for Surveillance and Applied Research. 2024.
***
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2024-10-30 |
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