🕷️ Crawler Inspector

URL Lookup

Direct Parameter Lookup

Raw Queries and Responses

1. Shard Calculation

Query:

Response:

Calculated Shard: 152 (from laksa178)

2. Crawled Status Check

Query:

curl -X POST \
  'http://laksa152.int.ahrefs:8124/' \
  -H 'Content-Type: text/plain' \
  -H 'X-ClickHouse-Database: crawler3' \
  -H 'Authorization: Basic YXBpOg==' \
  -d 'SELECT getAhrefsURLFromUnparsed(src_unparsed) AS found_url, ifNull(toUnixTimestamp(download_stamp), 0) AS crawl_time, ifNull(toUnixTimestamp(props_url_first_seen), 0) AS first_indexed_time, download_http_code AS http_code, src_unparsed AS src_unparsed, src_root_hash AS src_root_hash, history_drop_reason AS history_drop_reason, meta_title AS meta_title, meta_descriptions AS meta_descriptions, attrs_boilerpipe_text AS attrs_boilerpipe_text, attrs_markdown AS attrs_markdown, attrs_readable_markdown AS attrs_readable_markdown, meta_canonical AS meta_canonical FROM crawler3.page_info_local FINAL PREWHERE (src_root_hash, src_unparsed) IN ((getAhrefsRootHashFromUnparsed(getAhrefsUnparsedNoserviceFromURL(\'https://en.wikipedia.org/wiki/List_of_antidepressants\')), getAhrefsUnparsedNoserviceFromURL(\'https://en.wikipedia.org/wiki/List_of_antidepressants\'))) FORMAT JSONEachRow'

Response:

{"found_url":"https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants","crawl_time":1754489158,"first_indexed_time":0,"http_code":200,"src_unparsed":"org,wikipedia!en,\/wiki\/List_of_antidepressants s443","src_root_hash":"17790707453426894952","history_drop_reason":null,"meta_title":"List of antidepressants - Wikipedia","meta_descriptions":[],"attrs_boilerpipe_text":null,"attrs_markdown":"[Jump to content](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#bodyContent)\n\nMain menu\n\nMain menu\n\nmove to sidebar\n\nhide\n\nNavigation\n\n- [Main page](https:\/\/en.wikipedia.org\/wiki\/Main_Page \"Visit the main page [z]\")\n- [Contents](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:Contents \"Guides to browsing Wikipedia\")\n- [Current events](https:\/\/en.wikipedia.org\/wiki\/Portal:Current_events \"Articles related to current events\")\n- [Random article](https:\/\/en.wikipedia.org\/wiki\/Special:Random \"Visit a randomly selected article [x]\")\n- [About Wikipedia](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:About \"Learn about Wikipedia and how it works\")\n- [Contact us](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:Contact_us \"How to contact Wikipedia\")\n\nContribute\n\n- [Help](https:\/\/en.wikipedia.org\/wiki\/Help:Contents \"Guidance on how to use and edit Wikipedia\")\n- [Learn to edit](https:\/\/en.wikipedia.org\/wiki\/Help:Introduction \"Learn how to edit Wikipedia\")\n- [Community portal](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:Community_portal \"The hub for editors\")\n- [Recent changes](https:\/\/en.wikipedia.org\/wiki\/Special:RecentChanges \"A list of recent changes to Wikipedia [r]\")\n- [Upload file](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:File_upload_wizard \"Add images or other media for use on Wikipedia\")\n- [Special pages](https:\/\/en.wikipedia.org\/wiki\/Special:SpecialPages)\n\n[![](https:\/\/en.wikipedia.org\/static\/images\/icons\/wikipedia.png) ![Wikipedia](https:\/\/en.wikipedia.org\/static\/images\/mobile\/copyright\/wikipedia-wordmark-en.svg) ![The Free Encyclopedia](https:\/\/en.wikipedia.org\/static\/images\/mobile\/copyright\/wikipedia-tagline-en.svg)](https:\/\/en.wikipedia.org\/wiki\/Main_Page)\n\n[Search](https:\/\/en.wikipedia.org\/wiki\/Special:Search \"Search Wikipedia [f]\")\n\nAppearance\n\n- [Donate](https:\/\/donate.wikimedia.org\/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en)\n- [Create account](https:\/\/en.wikipedia.org\/w\/index.php?title=Special:CreateAccount&returnto=List+of+antidepressants \"You are encouraged to create an account and log in; however, it is not mandatory\")\n- [Log in](https:\/\/en.wikipedia.org\/w\/index.php?title=Special:UserLogin&returnto=List+of+antidepressants \"You're encouraged to log in; however, it's not mandatory. [o]\")\n\nPersonal tools\n\n- [Donate](https:\/\/donate.wikimedia.org\/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en)\n- [Create account](https:\/\/en.wikipedia.org\/w\/index.php?title=Special:CreateAccount&returnto=List+of+antidepressants \"You are encouraged to create an account and log in; however, it is not mandatory\")\n- [Log in](https:\/\/en.wikipedia.org\/w\/index.php?title=Special:UserLogin&returnto=List+of+antidepressants \"You're encouraged to log in; however, it's not mandatory. [o]\")\n\nPages for logged out editors [learn more](https:\/\/en.wikipedia.org\/wiki\/Help:Introduction)\n\n- [Contributions](https:\/\/en.wikipedia.org\/wiki\/Special:MyContributions \"A list of edits made from this IP address [y]\")\n- [Talk](https:\/\/en.wikipedia.org\/wiki\/Special:MyTalk \"Discussion about edits from this IP address [n]\")\n\n## Contents\nmove to sidebar\n\nhide\n\n- [(Top)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants)\n- [1 Selective serotonin reuptake inhibitors (SSRIs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Selective_serotonin_reuptake_inhibitors_\\(SSRIs\\))\n  Toggle Selective serotonin reuptake inhibitors (SSRIs) subsection\n  - [1\\.1 Discontinued\/withdrawn](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Discontinued\/withdrawn)\n- [2 Serotonin–norepinephrine reuptake inhibitors (SNRIs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Serotonin%E2%80%93norepinephrine_reuptake_inhibitors_\\(SNRIs\\))\n- [3 Serotonin–dopamine reuptake inhibitor (SDRIs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Serotonin%E2%80%93dopamine_reuptake_inhibitor_\\(SDRIs\\))\n  Toggle Serotonin–dopamine reuptake inhibitor (SDRIs) subsection\n  - [3\\.1 Discontinued\/withdrawn](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Discontinued\/withdrawn_2)\n- [4 Serotonin–norepinephrine–dopamine reuptake inhibitors (SNDRIs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Serotonin%E2%80%93norepinephrine%E2%80%93dopamine_reuptake_inhibitors_\\(SNDRIs\\))\n- [5 Serotonin modulators and stimulators (SMSs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Serotonin_modulators_and_stimulators_\\(SMSs\\))\n- [6 Serotonin antagonist and reuptake inhibitors (SARIs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Serotonin_antagonist_and_reuptake_inhibitors_\\(SARIs\\))\n  Toggle Serotonin antagonist and reuptake inhibitors (SARIs) subsection\n  - [6\\.1 Discontinued\/withdrawn](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Discontinued\/withdrawn_3)\n- [7 Norepinephrine reuptake inhibitors (NRIs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Norepinephrine_reuptake_inhibitors_\\(NRIs\\))\n  Toggle Norepinephrine reuptake inhibitors (NRIs) subsection\n  - [7\\.1 Off-label only](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Off-label_only)\n- [8 Norepinephrine–dopamine reuptake inhibitors (NDRIs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Norepinephrine%E2%80%93dopamine_reuptake_inhibitors_\\(NDRIs\\))\n  Toggle Norepinephrine–dopamine reuptake inhibitors (NDRIs) subsection\n  - [8\\.1 Off-label only](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Off-label_only_2)\n  - [8\\.2 Discontinued\/withdrawn](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Discontinued\/withdrawn_4)\n- [9 Tricyclic antidepressants (TCAs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Tricyclic_antidepressants_\\(TCAs\\))\n  Toggle Tricyclic antidepressants (TCAs) subsection\n  - [9\\.1 Discontinued\/withdrawn](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Discontinued\/withdrawn_5)\n- [10 Tetracyclic antidepressants (TeCAs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Tetracyclic_antidepressants_\\(TeCAs\\))\n- [11 Monoamine oxidase inhibitors (MAOIs)](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Monoamine_oxidase_inhibitors_\\(MAOIs\\))\n  Toggle Monoamine oxidase inhibitors (MAOIs) subsection\n  - [11\\.1 Irreversible](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Irreversible)\n    - [11\\.1.1 Non-selective](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Non-selective)\n    - [11\\.1.2 Selective for MAO-B](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Selective_for_MAO-B)\n  - [11\\.2 Reversible](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Reversible)\n    - [11\\.2.1 Non-selective](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Non-selective_2)\n    - [11\\.2.2 Selective for MAO-A](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Selective_for_MAO-A)\n  - [11\\.3 Mixed](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Mixed)\n    - [11\\.3.1 Non-selective](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Non-selective_3)\n- [12 Atypical antipsychotics](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Atypical_antipsychotics)\n- [13 Others](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Others)\n  Toggle Others subsection\n  - [13\\.1 Marketed](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Marketed)\n  - [13\\.2 Off-label only](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Off-label_only_3)\n  - [13\\.3 Discontinued\/withdrawn](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Discontinued\/withdrawn_6)\n  - [13\\.4 Over-the-counter](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Over-the-counter)\n- [14 Adjunctive treatments](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Adjunctive_treatments)\n  Toggle Adjunctive treatments subsection\n  - [14\\.1 Atypical antipsychotics](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Atypical_antipsychotics_2)\n    - [14\\.1.1 Off-label only](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Off-label_only_4)\n  - [14\\.2 Typical antipsychotics](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Typical_antipsychotics)\n    - [14\\.2.1 Off-label only](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Off-label_only_5)\n  - [14\\.3 Dopamine reuptake inhibitor](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Dopamine_reuptake_inhibitor)\n    - [14\\.3.1 Off-label only](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Off-label_only_6)\n  - [14\\.4 Others](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Others_2)\n    - [14\\.4.1 Off-label only](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Off-label_only_7)\n- [15 Combination products](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#Combination_products)\n- [16 See also](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#See_also)\n- [17 References](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#References)\n\nToggle the table of contents\n\n# List of antidepressants\n2 languages\n\n- [Português](https:\/\/pt.wikipedia.org\/wiki\/Lista_de_antidepressivos \"Lista de antidepressivos – Portuguese\")\n- [سنڌي](https:\/\/sd.wikipedia.org\/wiki\/%D8%A7%D9%8A%D9%86%D9%BD%D9%8A_%DA%8A%D9%BE%D8%B1%D9%8A%D8%B4%D9%86_%D8%AF%D9%88%D8%A7%D8%A6%D9%86_%D8%AC%D9%8A_%D9%81%D9%87%D8%B1%D8%B3%D8%AA \"اينٽي ڊپريشن دوائن جي فهرست – Sindhi\")\n\n[Edit links](https:\/\/www.wikidata.org\/wiki\/Special:EntityPage\/Q6606027#sitelinks-wikipedia \"Edit interlanguage links\")\n\n- [Article](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants \"View the content page [c]\")\n- [Talk](https:\/\/en.wikipedia.org\/wiki\/Talk:List_of_antidepressants \"Discuss improvements to the content page [t]\")\n\nEnglish\n\n- [Read](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants)\n- [Edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit \"Edit this page [e]\")\n- [View history](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=history \"Past revisions of this page [h]\")\n\nTools\n\nTools\n\nmove to sidebar\n\nhide\n\nActions\n\n- [Read](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants)\n- [Edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit \"Edit this page [e]\")\n- [View history](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=history)\n\nGeneral\n\n- [What links here](https:\/\/en.wikipedia.org\/wiki\/Special:WhatLinksHere\/List_of_antidepressants \"List of all English Wikipedia pages containing links to this page [j]\")\n- [Related changes](https:\/\/en.wikipedia.org\/wiki\/Special:RecentChangesLinked\/List_of_antidepressants \"Recent changes in pages linked from this page [k]\")\n- [Upload file](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:File_Upload_Wizard \"Upload files [u]\")\n- [Permanent link](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&oldid=1289313995 \"Permanent link to this revision of this page\")\n- [Page information](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=info \"More information about this page\")\n- [Cite this page](https:\/\/en.wikipedia.org\/w\/index.php?title=Special:CiteThisPage&page=List_of_antidepressants&id=1289313995&wpFormIdentifier=titleform \"Information on how to cite this page\")\n- [Get shortened URL](https:\/\/en.wikipedia.org\/w\/index.php?title=Special:UrlShortener&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FList_of_antidepressants)\n- [Download QR code](https:\/\/en.wikipedia.org\/w\/index.php?title=Special:QrCode&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FList_of_antidepressants)\n\nPrint\/export\n\n- [Download as PDF](https:\/\/en.wikipedia.org\/w\/index.php?title=Special:DownloadAsPdf&page=List_of_antidepressants&action=show-download-screen \"Download this page as a PDF file\")\n- [Printable version](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&printable=yes \"Printable version of this page [p]\")\n\nIn other projects\n\n- [Wikidata item](https:\/\/www.wikidata.org\/wiki\/Special:EntityPage\/Q6606027 \"Structured data on this page hosted by Wikidata [g]\")\n\nAppearance\n\nmove to sidebar\n\nhide\n\nFrom Wikipedia, the free encyclopedia\n\nThis is a complete **list of clinically approved prescription antidepressants** throughout the world, as well as clinically approved prescription drugs used to augment [antidepressants](https:\/\/en.wikipedia.org\/wiki\/Antidepressant \"Antidepressant\") or [mood stabilizers](https:\/\/en.wikipedia.org\/wiki\/Mood_stabilizer \"Mood stabilizer\"), by pharmacological and\/or structural classification. *Chemical\/generic names are listed first, with brand names in parentheses. All drugs listed are approved specifically for [major depressive disorder](https:\/\/en.wikipedia.org\/wiki\/Major_depressive_disorder \"Major depressive disorder\") unless noted otherwise.*\n\n## Selective serotonin reuptake inhibitors (SSRIs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=1 \"Edit section: Selective serotonin reuptake inhibitors (SSRIs)\")\\]\n\n[Selective serotonin reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Selective_serotonin_reuptake_inhibitor \"Selective serotonin reuptake inhibitor\") include:\n\n- [Citalopram](https:\/\/en.wikipedia.org\/wiki\/Citalopram \"Citalopram\") (Celexa, Cipramil)\n- [Escitalopram](https:\/\/en.wikipedia.org\/wiki\/Escitalopram \"Escitalopram\") (Lexapro, Cipralex)\n- [Fluoxetine](https:\/\/en.wikipedia.org\/wiki\/Fluoxetine \"Fluoxetine\") (Prozac, Sarafem)\n- [Fluvoxamine](https:\/\/en.wikipedia.org\/wiki\/Fluvoxamine \"Fluvoxamine\") (Luvox, Faverin)\n- [Paroxetine](https:\/\/en.wikipedia.org\/wiki\/Paroxetine \"Paroxetine\") (Paxil, Seroxat)\n- [Sertraline](https:\/\/en.wikipedia.org\/wiki\/Sertraline \"Sertraline\") (Zoloft, Lustral)\n\n### Discontinued\/withdrawn\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=2 \"Edit section: Discontinued\/withdrawn\")\\]\n\n- [Indalpine](https:\/\/en.wikipedia.org\/wiki\/Indalpine \"Indalpine\") (Upstene)\n- [Zimelidine](https:\/\/en.wikipedia.org\/wiki\/Zimelidine \"Zimelidine\") (Normud, Zelmid)\n\n## Serotonin–norepinephrine reuptake inhibitors (SNRIs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=3 \"Edit section: Serotonin–norepinephrine reuptake inhibitors (SNRIs)\")\\]\n\n[Serotonin–norepinephrine reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Serotonin%E2%80%93norepinephrine_reuptake_inhibitor \"Serotonin–norepinephrine reuptake inhibitor\") include:\n\n- [Desvenlafaxine](https:\/\/en.wikipedia.org\/wiki\/Desvenlafaxine \"Desvenlafaxine\") (Pristiq)\n- [Duloxetine](https:\/\/en.wikipedia.org\/wiki\/Duloxetine \"Duloxetine\") (Cymbalta)\n- [Levomilnacipran](https:\/\/en.wikipedia.org\/wiki\/Levomilnacipran \"Levomilnacipran\") (Fetzima)\n- [Milnacipran](https:\/\/en.wikipedia.org\/wiki\/Milnacipran \"Milnacipran\") (Ixel, Savella, Milnaneurax)\n- [Venlafaxine](https:\/\/en.wikipedia.org\/wiki\/Venlafaxine \"Venlafaxine\") (Effexor, Trevilor)\n\n## Serotonin–dopamine reuptake inhibitor (SDRIs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=4 \"Edit section: Serotonin–dopamine reuptake inhibitor (SDRIs)\")\\]\n\n[Serotonin–dopamine reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Serotonin%E2%80%93dopamine_reuptake_inhibitor \"Serotonin–dopamine reuptake inhibitor\") include:\n\n*None currently marketed*\n\n### Discontinued\/withdrawn\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=5 \"Edit section: Discontinued\/withdrawn\")\\]\n\n- [Medifoxamine](https:\/\/en.wikipedia.org\/wiki\/Medifoxamine \"Medifoxamine\") (Clédial, Gerdaxyl)\n\n## Serotonin–norepinephrine–dopamine reuptake inhibitors (SNDRIs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=6 \"Edit section: Serotonin–norepinephrine–dopamine reuptake inhibitors (SNDRIs)\")\\]\n\n[Serotonin–norepinephrine–dopamine reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Serotonin%E2%80%93norepinephrine%E2%80%93dopamine_reuptake_inhibitor \"Serotonin–norepinephrine–dopamine reuptake inhibitor\") include:\n\n- [Toludesvenlafaxine](https:\/\/en.wikipedia.org\/wiki\/Toludesvenlafaxine \"Toludesvenlafaxine\") (Ruoxinlin)\n- [Nefazodone](https:\/\/en.wikipedia.org\/wiki\/Nefazodone \"Nefazodone\") (Serzone)[\\[1\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-Tatsumi1997-1)\n- [Auvelity](https:\/\/en.wikipedia.org\/wiki\/Dextromethorphan\/bupropion \"Dextromethorphan\/bupropion\") (Dextromethorphan\/bupropion)\n\n## Serotonin modulators and stimulators (SMSs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=7 \"Edit section: Serotonin modulators and stimulators (SMSs)\")\\]\n\n[Serotonin modulators and stimulators](https:\/\/en.wikipedia.org\/wiki\/Serotonin_modulators_and_stimulators \"Serotonin modulators and stimulators\") include:\n\n- [Vilazodone](https:\/\/en.wikipedia.org\/wiki\/Vilazodone \"Vilazodone\") (Viibryd)\n- [Vortioxetine](https:\/\/en.wikipedia.org\/wiki\/Vortioxetine \"Vortioxetine\") (Trintellix, Brintellix)\n\n## Serotonin antagonist and reuptake inhibitors (SARIs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=8 \"Edit section: Serotonin antagonist and reuptake inhibitors (SARIs)\")\\]\n\n[Serotonin antagonist and reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Serotonin_antagonist_and_reuptake_inhibitor \"Serotonin antagonist and reuptake inhibitor\") include:\n\n- [Nefazodone](https:\/\/en.wikipedia.org\/wiki\/Nefazodone \"Nefazodone\") (Dutonin, Nefadar, Serzone) – withdrawn\/discontinued in most countries\n- [Trazodone](https:\/\/en.wikipedia.org\/wiki\/Trazodone \"Trazodone\") (Desyrel)\n\n### Discontinued\/withdrawn\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=9 \"Edit section: Discontinued\/withdrawn\")\\]\n\n- [Etoperidone](https:\/\/en.wikipedia.org\/wiki\/Etoperidone \"Etoperidone\") (Axiomin, Etonin)\n\n## Norepinephrine reuptake inhibitors (NRIs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=10 \"Edit section: Norepinephrine reuptake inhibitors (NRIs)\")\\]\n\n[Norepinephrine reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Norepinephrine_reuptake_inhibitor \"Norepinephrine reuptake inhibitor\") include:\n\n- [Reboxetine](https:\/\/en.wikipedia.org\/wiki\/Reboxetine \"Reboxetine\") (Edronax)\n- [Teniloxazine](https:\/\/en.wikipedia.org\/wiki\/Teniloxazine \"Teniloxazine\") (Lucelan, Metatone) – also a [5-HT2A receptor](https:\/\/en.wikipedia.org\/wiki\/5-HT2A_receptor \"5-HT2A receptor\") antagonist\n- [Viloxazine](https:\/\/en.wikipedia.org\/wiki\/Viloxazine \"Viloxazine\") (Qelbree, formerly Vivalan) – also a [5-HT2B receptor](https:\/\/en.wikipedia.org\/wiki\/5-HT2B_receptor \"5-HT2B receptor\") antagonist and [5-HT2C receptor](https:\/\/en.wikipedia.org\/wiki\/5-HT2C_receptor \"5-HT2C receptor\") [agonist](https:\/\/en.wikipedia.org\/wiki\/Agonist \"Agonist\")\n\n### Off-label only\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=11 \"Edit section: Off-label only\")\\]\n\n- [Atomoxetine](https:\/\/en.wikipedia.org\/wiki\/Atomoxetine \"Atomoxetine\") (Strattera)[\\[2\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid29630286-2)[\\[3\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid21155988-3)[\\[4\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid19752841-4)[\\[5\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid25295426-5)\n\n## Norepinephrine–dopamine reuptake inhibitors (NDRIs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=12 \"Edit section: Norepinephrine–dopamine reuptake inhibitors (NDRIs)\")\\]\n\n[Norepinephrine–dopamine reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Norepinephrine%E2%80%93dopamine_reuptake_inhibitor \"Norepinephrine–dopamine reuptake inhibitor\") include:\n\n- [Bupropion](https:\/\/en.wikipedia.org\/wiki\/Bupropion \"Bupropion\") (Wellbutrin, Elontril) – also a [non-competitive antagonist](https:\/\/en.wikipedia.org\/wiki\/Non-competitive_antagonist \"Non-competitive antagonist\") of [nicotinic acetylcholine receptors](https:\/\/en.wikipedia.org\/wiki\/Nicotinic_acetylcholine_receptor \"Nicotinic acetylcholine receptor\")[\\[6\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid19897080-6)\n\n### Off-label only\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=13 \"Edit section: Off-label only\")\\]\n\n- [Amphetamines](https:\/\/en.wikipedia.org\/wiki\/Amphetamine \"Amphetamine\") ([Adderall](https:\/\/en.wikipedia.org\/wiki\/Adderall \"Adderall\"), [Vyvanse](https:\/\/en.wikipedia.org\/wiki\/Vyvanse \"Vyvanse\")) – actually [norepinephrine–dopamine releasing agents](https:\/\/en.wikipedia.org\/wiki\/Norepinephrine%E2%80%93dopamine_releasing_agent \"Norepinephrine–dopamine releasing agent\") (NDRAs)[\\[7\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid25813654-7)[\\[5\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid25295426-5)\n- [Methylphenidate](https:\/\/en.wikipedia.org\/wiki\/Methylphenidate \"Methylphenidate\") (Ritalin, Concerta)[\\[8\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid10907387-8)[\\[9\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid22144657-9)\n\n### Discontinued\/withdrawn\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=14 \"Edit section: Discontinued\/withdrawn\")\\]\n\n- [Amineptine](https:\/\/en.wikipedia.org\/wiki\/Amineptine \"Amineptine\") (Survector, Maneon)\n- [Nomifensine](https:\/\/en.wikipedia.org\/wiki\/Nomifensine \"Nomifensine\") (Merital, Alival)\n\n## Tricyclic antidepressants (TCAs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=15 \"Edit section: Tricyclic antidepressants (TCAs)\")\\]\n\n[Tricyclic antidepressants](https:\/\/en.wikipedia.org\/wiki\/Tricyclic_antidepressants \"Tricyclic antidepressants\") include:\n\n- [Amitriptyline](https:\/\/en.wikipedia.org\/wiki\/Amitriptyline \"Amitriptyline\") (Elavil, Endep)\n- [Amitriptylinoxide](https:\/\/en.wikipedia.org\/wiki\/Amitriptylinoxide \"Amitriptylinoxide\") (Amioxid, Ambivalon, Equilibrin)\n- [Amoxapine](https:\/\/en.wikipedia.org\/wiki\/Amoxapine \"Amoxapine\") (Asendin)\n- [Clomipramine](https:\/\/en.wikipedia.org\/wiki\/Clomipramine \"Clomipramine\") (Anafranil)\n- [Desipramine](https:\/\/en.wikipedia.org\/wiki\/Desipramine \"Desipramine\") (Norpramin, Pertofrane)\n- [Dibenzepin](https:\/\/en.wikipedia.org\/wiki\/Dibenzepin \"Dibenzepin\") (Noveril, Victoril)\n- [Dimetacrine](https:\/\/en.wikipedia.org\/wiki\/Dimetacrine \"Dimetacrine\") (Istonil)\n- [Dosulepin](https:\/\/en.wikipedia.org\/wiki\/Dosulepin \"Dosulepin\") (Prothiaden)\n- [Doxepin](https:\/\/en.wikipedia.org\/wiki\/Doxepin \"Doxepin\") (Adapin, Sinequan)\n- [Imipramine](https:\/\/en.wikipedia.org\/wiki\/Imipramine \"Imipramine\") (Tofranil)\n- [Lofepramine](https:\/\/en.wikipedia.org\/wiki\/Lofepramine \"Lofepramine\") (Lomont, Gamanil)\n- [Melitracen](https:\/\/en.wikipedia.org\/wiki\/Melitracen \"Melitracen\") (Dixeran, Melixeran, Trausabun)\n- [Nitroxazepine](https:\/\/en.wikipedia.org\/wiki\/Nitroxazepine \"Nitroxazepine\") (Sintamil)\n- [Nortriptyline](https:\/\/en.wikipedia.org\/wiki\/Nortriptyline \"Nortriptyline\") (Pamelor, Aventyl)\n- [Noxiptiline](https:\/\/en.wikipedia.org\/wiki\/Noxiptiline \"Noxiptiline\") (Agedal, Elronon, Nogedal)\n- [Pipofezine](https:\/\/en.wikipedia.org\/wiki\/Pipofezine \"Pipofezine\") (Azafen\/Azaphen)\n- [Protriptyline](https:\/\/en.wikipedia.org\/wiki\/Protriptyline \"Protriptyline\") (Vivactil)\n- [Trimipramine](https:\/\/en.wikipedia.org\/wiki\/Trimipramine \"Trimipramine\") (Surmontil)\n\n[Opipramol](https:\/\/en.wikipedia.org\/wiki\/Opipramol \"Opipramol\") (Insidon), [tianeptine](https:\/\/en.wikipedia.org\/wiki\/Tianeptine \"Tianeptine\") (Stablon, Coaxil) and [amineptine](https:\/\/en.wikipedia.org\/wiki\/Amineptine \"Amineptine\") (discontinued; formerly Survector, Maneon) are chemically TCAs but are [pharmacodynamically](https:\/\/en.wikipedia.org\/wiki\/Pharmacodynamics \"Pharmacodynamics\") atypical, and are therefore grouped elsewhere.\n\n### Discontinued\/withdrawn\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=16 \"Edit section: Discontinued\/withdrawn\")\\]\n\n- [Butriptyline](https:\/\/en.wikipedia.org\/wiki\/Butriptyline \"Butriptyline\") (Evadyne)\n- [Demexiptiline](https:\/\/en.wikipedia.org\/wiki\/Demexiptiline \"Demexiptiline\") (Deparon, Tinoran)\n- [Fluacizine](https:\/\/en.wikipedia.org\/wiki\/Fluacizine \"Fluacizine\") (Phtorazisin)\n- [Imipraminoxide](https:\/\/en.wikipedia.org\/wiki\/Imipraminoxide \"Imipraminoxide\") (Imiprex, Elepsin)\n- [Iprindole](https:\/\/en.wikipedia.org\/wiki\/Iprindole \"Iprindole\") (Prondol, Galatur, Tetran)\n- [Metapramine](https:\/\/en.wikipedia.org\/wiki\/Metapramine \"Metapramine\") (Timaxel)\n- [Propizepine](https:\/\/en.wikipedia.org\/wiki\/Propizepine \"Propizepine\") (Depressin, Vagran)\n- [Quinupramine](https:\/\/en.wikipedia.org\/wiki\/Quinupramine \"Quinupramine\") (Kinupril, Kevopril)\n- [Tiazesim](https:\/\/en.wikipedia.org\/wiki\/Tiazesim \"Tiazesim\") (Altinil) – actually not a TCA but a [tricyclic-like antidepressant](https:\/\/en.wikipedia.org\/wiki\/Heterocyclic_antidepressant \"Heterocyclic antidepressant\")\n- [Tofenacin](https:\/\/en.wikipedia.org\/wiki\/Tofenacin \"Tofenacin\") (Elamol, Tofacine) – actually not a TCA but a [tricyclic-like antidepressant](https:\/\/en.wikipedia.org\/wiki\/Heterocyclic_antidepressant \"Heterocyclic antidepressant\")\n\n## Tetracyclic antidepressants (TeCAs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=17 \"Edit section: Tetracyclic antidepressants (TeCAs)\")\\]\n\n[Tetracyclic antidepressants](https:\/\/en.wikipedia.org\/wiki\/Tetracyclic_antidepressants \"Tetracyclic antidepressants\") include:\n\n- [Maprotiline](https:\/\/en.wikipedia.org\/wiki\/Maprotiline \"Maprotiline\") (Ludiomil)\n- [Mianserin](https:\/\/en.wikipedia.org\/wiki\/Mianserin \"Mianserin\") (Tolvon)\n- [Mirtazapine](https:\/\/en.wikipedia.org\/wiki\/Mirtazapine \"Mirtazapine\") (Remeron)\n- [Setiptiline](https:\/\/en.wikipedia.org\/wiki\/Setiptiline \"Setiptiline\") (Tecipul)\n\nMianserin, mirtazapine, and setiptiline are also sometimes described as *[noradrenergic and specific serotonergic antidepressants](https:\/\/en.wikipedia.org\/wiki\/Noradrenergic_and_specific_serotonergic_antidepressant \"Noradrenergic and specific serotonergic antidepressant\")* (NaSSAs).\n\n## Monoamine oxidase inhibitors (MAOIs)\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=18 \"Edit section: Monoamine oxidase inhibitors (MAOIs)\")\\]\n\n[Monoamine oxidase inhibitors](https:\/\/en.wikipedia.org\/wiki\/Monoamine_oxidase_inhibitor \"Monoamine oxidase inhibitor\") include\n\n### Irreversible\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=19 \"Edit section: Irreversible\")\\]\n\n#### Non-selective\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=20 \"Edit section: Non-selective\")\\]\n\n- [Isocarboxazid](https:\/\/en.wikipedia.org\/wiki\/Isocarboxazid \"Isocarboxazid\") (Marplan)\n- [Phenelzine](https:\/\/en.wikipedia.org\/wiki\/Phenelzine \"Phenelzine\") (Nardil)\n- [Tranylcypromine](https:\/\/en.wikipedia.org\/wiki\/Tranylcypromine \"Tranylcypromine\") (Parnate)\n\n*Discontinued\/withdrawn*\n\n- [Benmoxin](https:\/\/en.wikipedia.org\/wiki\/Benmoxin \"Benmoxin\") (Neuralex)\n- [Iproclozide](https:\/\/en.wikipedia.org\/wiki\/Iproclozide \"Iproclozide\") (Sursum)\n- [Iproniazid](https:\/\/en.wikipedia.org\/wiki\/Iproniazid \"Iproniazid\") (Marsilid)\n- [Mebanazine](https:\/\/en.wikipedia.org\/wiki\/Mebanazine \"Mebanazine\") (Actomol)\n- [Nialamide](https:\/\/en.wikipedia.org\/wiki\/Nialamide \"Nialamide\") (Niamid)\n- [Octamoxin](https:\/\/en.wikipedia.org\/wiki\/Octamoxin \"Octamoxin\") (Ximaol)\n- [Pheniprazine](https:\/\/en.wikipedia.org\/wiki\/Pheniprazine \"Pheniprazine\") (Catron)\n- [Phenoxypropazine](https:\/\/en.wikipedia.org\/wiki\/Phenoxypropazine \"Phenoxypropazine\") (Drazine)\n- [Pivhydrazine](https:\/\/en.wikipedia.org\/wiki\/Pivhydrazine \"Pivhydrazine\") (Tersavid)\n- [Safrazine](https:\/\/en.wikipedia.org\/wiki\/Safrazine \"Safrazine\") (Safra)\n\n#### Selective for MAO-B\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=21 \"Edit section: Selective for MAO-B\")\\]\n\n- [Selegiline](https:\/\/en.wikipedia.org\/wiki\/Selegiline \"Selegiline\") (Eldepryl, Zelapar, Emsam) – also a [catecholaminergic activity enhancer](https:\/\/en.wikipedia.org\/wiki\/Monoamine_activity_enhancer \"Monoamine activity enhancer\") and weak [norepinephrine releasing agent](https:\/\/en.wikipedia.org\/wiki\/Norepinephrine_releasing_agent \"Norepinephrine releasing agent\") (via [metabolites](https:\/\/en.wikipedia.org\/wiki\/Metabolite \"Metabolite\"))\n\n### Reversible\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=22 \"Edit section: Reversible\")\\]\n\n#### Non-selective\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=23 \"Edit section: Non-selective\")\\]\n\n*Discontinued\/withdrawn*\n\n- [Caroxazone](https:\/\/en.wikipedia.org\/wiki\/Caroxazone \"Caroxazone\") (Surodil, Timostenil)\n\n#### Selective for MAO-A\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=24 \"Edit section: Selective for MAO-A\")\\]\n\n- [Metralindole](https:\/\/en.wikipedia.org\/wiki\/Metralindole \"Metralindole\") (Inkazan)\n- [Moclobemide](https:\/\/en.wikipedia.org\/wiki\/Moclobemide \"Moclobemide\") (Aurorix, Manerix)\n- [Pirlindole](https:\/\/en.wikipedia.org\/wiki\/Pirlindole \"Pirlindole\") (Pirazidol)\n\nThese drugs are sometimes described as *[reversible inhibitors of MAO-A](https:\/\/en.wikipedia.org\/wiki\/Reversible_inhibitor_of_MAO-A \"Reversible inhibitor of MAO-A\")* (RIMAs).\n\n*Discontinued\/withdrawn*\n\n- [Eprobemide](https:\/\/en.wikipedia.org\/wiki\/Eprobemide \"Eprobemide\") (Befol)\n- [Minaprine](https:\/\/en.wikipedia.org\/wiki\/Minaprine \"Minaprine\") (Brantur, Cantor)\n- [Toloxatone](https:\/\/en.wikipedia.org\/wiki\/Toloxatone \"Toloxatone\") (Humoryl)\n\n### Mixed\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=25 \"Edit section: Mixed\")\\]\n\n#### Non-selective\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=26 \"Edit section: Non-selective\")\\]\n\n- [Bifemelane](https:\/\/en.wikipedia.org\/wiki\/Bifemelane \"Bifemelane\") (Alnert, Celeport) – RIMA, irreversible inhibitor of MAO-B, and weak NRI\n\n## Atypical antipsychotics\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=27 \"Edit section: Atypical antipsychotics\")\\]\n\n[Atypical antipsychotics](https:\/\/en.wikipedia.org\/wiki\/Atypical_antipsychotic \"Atypical antipsychotic\") include:\n\n- [Amisulpride](https:\/\/en.wikipedia.org\/wiki\/Amisulpride \"Amisulpride\") (Solian) – approved in low doses as a monotherapy for [persistent depression](https:\/\/en.wikipedia.org\/wiki\/Dysthymia \"Dysthymia\") and major depressive disorder[\\[10\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-AdisInsight-Amisulpride-10)\n- [Levosulpiride](https:\/\/en.wikipedia.org\/wiki\/Levosulpiride \"Levosulpiride\") – approved in low doses for major depressive disorder[\\[11\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-AdisInsight-Levosulpiride-11)\n- [Lumateperone](https:\/\/en.wikipedia.org\/wiki\/Lumateperone \"Lumateperone\") (Caplyta) – approved as a monotherapy for [bipolar depression](https:\/\/en.wikipedia.org\/wiki\/Bipolar_depression \"Bipolar depression\")\n- [Lurasidone](https:\/\/en.wikipedia.org\/wiki\/Lurasidone \"Lurasidone\") (Latuda) – approved as a monotherapy for bipolar depression\n- [Quetiapine](https:\/\/en.wikipedia.org\/wiki\/Quetiapine \"Quetiapine\") (Seroquel) – approved as a monotherapy for bipolar depression\n- [Sulpiride](https:\/\/en.wikipedia.org\/wiki\/Sulpiride \"Sulpiride\") – approved in low doses as a monotherapy for major depressive disorder[\\[12\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-Sulpiride-Japanese-Label-12)\n\n## Others\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=28 \"Edit section: Others\")\\]\n\n### Marketed\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=29 \"Edit section: Marketed\")\\]\n\n- [D-Phenylalanine](https:\/\/en.wikipedia.org\/wiki\/D-Phenylalanine \"D-Phenylalanine\")\n  (DPA,\n  D\n  \\-Phe; Deprenon, Sabiben, Sabiden) – [enkephalinase inhibitor](https:\/\/en.wikipedia.org\/wiki\/Enkephalinase_inhibitor \"Enkephalinase inhibitor\")\n- [Agomelatine](https:\/\/en.wikipedia.org\/wiki\/Agomelatine \"Agomelatine\") (Valdoxan) – [5-HT2C receptor](https:\/\/en.wikipedia.org\/wiki\/5-HT2C_receptor \"5-HT2C receptor\") [antagonist](https:\/\/en.wikipedia.org\/wiki\/Receptor_antagonist \"Receptor antagonist\") and [MT1](https:\/\/en.wikipedia.org\/wiki\/Melatonin_receptor_1A \"Melatonin receptor 1A\") and [MT2 receptor](https:\/\/en.wikipedia.org\/wiki\/Melatonin_receptor_1B \"Melatonin receptor 1B\") agonist\n- [Auvelity](https:\/\/en.wikipedia.org\/wiki\/Dextromethorphan\/bupropion \"Dextromethorphan\/bupropion\") (Dextromethorphan\/bupropion)\n- [Brexanolone](https:\/\/en.wikipedia.org\/wiki\/Brexanolone \"Brexanolone\") (allopregnanolone; Zulresso) – [GABAA receptor positive allosteric modulator](https:\/\/en.wikipedia.org\/wiki\/GABAA_receptor \"GABAA receptor\") – approved for [postpartum depression](https:\/\/en.wikipedia.org\/wiki\/Postpartum_depression \"Postpartum depression\")\n- [Esketamine](https:\/\/en.wikipedia.org\/wiki\/Esketamine \"Esketamine\") (Spravato) – non-competitive NMDA receptor antagonist, other actions[\\[13\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-SpravatoLabel-13)\n- [Gepirone](https:\/\/en.wikipedia.org\/wiki\/Gepirone \"Gepirone\") (Exxua) – [5-HT1A receptor](https:\/\/en.wikipedia.org\/wiki\/5-HT1A_receptor \"5-HT1A receptor\") [partial agonist](https:\/\/en.wikipedia.org\/wiki\/Partial_agonist \"Partial agonist\") and [α2\\-adrenergic receptor](https:\/\/en.wikipedia.org\/wiki\/Alpha-2_adrenergic_receptor \"Alpha-2 adrenergic receptor\") antagonist\n- [Opipramol](https:\/\/en.wikipedia.org\/wiki\/Opipramol \"Opipramol\") (Insidon) — [σ1 receptor](https:\/\/en.wikipedia.org\/wiki\/Sigma-1_receptor \"Sigma-1 receptor\") agonist, other actions\n- [Tianeptine](https:\/\/en.wikipedia.org\/wiki\/Tianeptine \"Tianeptine\") (Stablon, Coaxil, Tianeurax) – weak and atypical [μ-opioid receptor](https:\/\/en.wikipedia.org\/wiki\/%CE%9C-opioid_receptor \"Μ-opioid receptor\") agonist, other actions\n\n### Off-label only\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=30 \"Edit section: Off-label only\")\\]\n\n- [Ketamine](https:\/\/en.wikipedia.org\/wiki\/Ketamine \"Ketamine\") (Ketalar) – non-competitive [NMDA receptor antagonist](https:\/\/en.wikipedia.org\/wiki\/NMDA_receptor_antagonist \"NMDA receptor antagonist\")[\\[14\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid26768892-14)\n\n### Discontinued\/withdrawn\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=31 \"Edit section: Discontinued\/withdrawn\")\\]\n\n- [α-Methyltryptamine](https:\/\/en.wikipedia.org\/wiki\/%CE%91-Methyltryptamine \"Α-Methyltryptamine\") \\[αMT\\] (Indopan) – non-selective [serotonin receptor agonist](https:\/\/en.wikipedia.org\/wiki\/Serotonin_receptor_agonist \"Serotonin receptor agonist\"), [serotonin–norepinephrine–dopamine releasing agent](https:\/\/en.wikipedia.org\/wiki\/Serotonin%E2%80%93norepinephrine%E2%80%93dopamine_releasing_agent \"Serotonin–norepinephrine–dopamine releasing agent\") (SNDRA), and weak RIMA\n- [Etryptamine](https:\/\/en.wikipedia.org\/wiki\/Etryptamine \"Etryptamine\") \\[α-Ethyltryptamine (αET)\\] (Monase) – non-selective serotonin receptor agonist, SNDRA, and weak RIMA\n- [Indeloxazine](https:\/\/en.wikipedia.org\/wiki\/Indeloxazine \"Indeloxazine\") (Elen, Noin) – [serotonin releasing agent](https:\/\/en.wikipedia.org\/wiki\/Serotonin_releasing_agent \"Serotonin releasing agent\") (SRA), NRI, and NMDA receptor antagonist\n- [Oxaflozane](https:\/\/en.wikipedia.org\/wiki\/Oxaflozane \"Oxaflozane\") (Conflictan) – 5-HT1A, 5-HT2A, and 5-HT2C receptor agonist\n- [Pivagabine](https:\/\/en.wikipedia.org\/wiki\/Pivagabine \"Pivagabine\") (Tonerg) – unknown\/unclear [mechanism of action](https:\/\/en.wikipedia.org\/wiki\/Mechanism_of_action \"Mechanism of action\")\n\n### Over-the-counter\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=32 \"Edit section: Over-the-counter\")\\]\n\nThe following antidepressants are available both with a [prescription](https:\/\/en.wikipedia.org\/wiki\/Medical_prescription \"Medical prescription\") and [over-the-counter](https:\/\/en.wikipedia.org\/wiki\/Over-the-counter \"Over-the-counter\"):\n\n- [Ademetionine](https:\/\/en.wikipedia.org\/wiki\/Ademetionine \"Ademetionine\") \\[*S*\\-Adenosyl-\n  L\n  \\-methionine (SAMe)\\] (Heptral, Transmetil, Samyl) – [cofactor](https:\/\/en.wikipedia.org\/wiki\/Cofactor_\\(biochemistry\\) \"Cofactor (biochemistry)\") in [monoamine neurotransmitter](https:\/\/en.wikipedia.org\/wiki\/Monoamine_neurotransmitter \"Monoamine neurotransmitter\") [biosynthesis](https:\/\/en.wikipedia.org\/wiki\/Biosynthesis \"Biosynthesis\")\n- *[Hypericum perforatum](https:\/\/en.wikipedia.org\/wiki\/Hypericum_perforatum \"Hypericum perforatum\")* \\[St. John's Wort (SJW)\\] (Jarsin, Kira, Movina) – [TRPC6](https:\/\/en.wikipedia.org\/wiki\/TRPC6 \"TRPC6\") activator, and various other actions\n- [Oxitriptan](https:\/\/en.wikipedia.org\/wiki\/Oxitriptan \"Oxitriptan\") \\[5-Hydroxytryptophan (5-HTP)\\] (Cincofarm, Levothym, Triptum) – [precursor](https:\/\/en.wikipedia.org\/wiki\/Precursor_\\(biochemistry\\) \"Precursor (biochemistry)\") in [serotonin](https:\/\/en.wikipedia.org\/wiki\/Serotonin \"Serotonin\") biosynthesis\n- [Tryptophan](https:\/\/en.wikipedia.org\/wiki\/Tryptophan \"Tryptophan\") (Tryptan, Optimax, Aminomine) – precursor in serotonin biosynthesis\n\n## Adjunctive treatments\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=33 \"Edit section: Adjunctive treatments\")\\]\n\n### Atypical antipsychotics\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=34 \"Edit section: Atypical antipsychotics\")\\]\n\n[Atypical antipsychotics](https:\/\/en.wikipedia.org\/wiki\/Atypical_antipsychotic \"Atypical antipsychotic\") include:\n\n- [Aripiprazole](https:\/\/en.wikipedia.org\/wiki\/Aripiprazole \"Aripiprazole\") (Abilify) – approved as an adjunct to antidepressant for major depression\n- [Brexpiprazole](https:\/\/en.wikipedia.org\/wiki\/Brexpiprazole \"Brexpiprazole\") (Rexulti) – approved as an adjunct to antidepressant for major depression\n- [Lumateperone](https:\/\/en.wikipedia.org\/wiki\/Lumateperone \"Lumateperone\") (Caplyta) – approved as an adjunct to mood stabilizer for bipolar depression\n- [Lurasidone](https:\/\/en.wikipedia.org\/wiki\/Lurasidone \"Lurasidone\") (Latuda) – approved as an adjunct to mood stabilizer for bipolar depression\n- [Olanzapine](https:\/\/en.wikipedia.org\/wiki\/Olanzapine \"Olanzapine\") (Zyprexa) – approved as an adjunct to antidepressant for major depression\n- [Quetiapine](https:\/\/en.wikipedia.org\/wiki\/Quetiapine \"Quetiapine\") (Seroquel) – approved as an adjunct to antidepressant or mood stabilizer for major depression and bipolar depression\n\n#### Off-label only\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=35 \"Edit section: Off-label only\")\\]\n\n- [Risperidone](https:\/\/en.wikipedia.org\/wiki\/Risperidone \"Risperidone\") (Risperdal)\n\n### Typical antipsychotics\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=36 \"Edit section: Typical antipsychotics\")\\]\n\n[Typical antipsychotics](https:\/\/en.wikipedia.org\/wiki\/Typical_antipsychotics \"Typical antipsychotics\") include:\n\n*None currently approved*\n\n#### Off-label only\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=37 \"Edit section: Off-label only\")\\]\n\n- [Trifluoperazine](https:\/\/en.wikipedia.org\/wiki\/Trifluoperazine \"Trifluoperazine\") (Stelazine)[\\[15\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid27514300-15)\n\n### Dopamine reuptake inhibitor\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=38 \"Edit section: Dopamine reuptake inhibitor\")\\]\n\n[Dopamine reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Dopamine_reuptake_inhibitor \"Dopamine reuptake inhibitor\") include:\n\n*None currently approved*\n\n#### Off-label only\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=39 \"Edit section: Off-label only\")\\]\n\n- [Modafinil](https:\/\/en.wikipedia.org\/wiki\/Modafinil \"Modafinil\") (Provigil)[\\[16\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid32447354-16)[\\[17\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid28318897-17)[\\[18\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid31643130-18)[\\[19\\]](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_note-pmid28256707-19)\n- [Armodafinil](https:\/\/en.wikipedia.org\/wiki\/Armodafinil \"Armodafinil\") (Nuvigil)\n\n### Others\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=40 \"Edit section: Others\")\\]\n\n#### Off-label only\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=41 \"Edit section: Off-label only\")\\]\n\n- [Buspirone](https:\/\/en.wikipedia.org\/wiki\/Buspirone \"Buspirone\") (Buspar) – 5-HT1A receptor partial agonist\n- [Lithium](https:\/\/en.wikipedia.org\/wiki\/Lithium_\\(medication\\) \"Lithium (medication)\") (Eskalith, Lithobid) – [mood stabilizer](https:\/\/en.wikipedia.org\/wiki\/Mood_stabilizer \"Mood stabilizer\") (mechanism of action unknown\/unclear)\n- [Thyroxine](https:\/\/en.wikipedia.org\/wiki\/Thyroxine \"Thyroxine\") (T4) – [thyroid hormone](https:\/\/en.wikipedia.org\/wiki\/Thyroid_hormone \"Thyroid hormone\") ([thyroid hormone receptor](https:\/\/en.wikipedia.org\/wiki\/Thyroid_hormone_receptor \"Thyroid hormone receptor\") agonist)\n- [Triiodothyronine](https:\/\/en.wikipedia.org\/wiki\/Triiodothyronine \"Triiodothyronine\") (T3) – thyroid hormone (thyroid hormone receptor agonist)\n\n## Combination products\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=42 \"Edit section: Combination products\")\\]\n\n- [Amitriptyline\/chlordiazepoxide](https:\/\/en.wikipedia.org\/wiki\/Amitriptyline\/chlordiazepoxide \"Amitriptyline\/chlordiazepoxide\") (Limbitrol) – TCA and [benzodiazepine](https:\/\/en.wikipedia.org\/wiki\/Benzodiazepine \"Benzodiazepine\") combination\n- [Amitriptyline\/perphenazine](https:\/\/en.wikipedia.org\/wiki\/Amitriptyline\/perphenazine \"Amitriptyline\/perphenazine\") (Etafron) – TCA and typical antipsychotic combination\n- [Bupropion\/dextromethorphan](https:\/\/en.wikipedia.org\/wiki\/Bupropion\/dextromethorphan \"Bupropion\/dextromethorphan\") (Auvelity) – [non-competitive](https:\/\/en.wikipedia.org\/wiki\/Non-competitive_antagonist \"Non-competitive antagonist\") NMDA receptor antagonist, [σ1 receptor](https:\/\/en.wikipedia.org\/wiki\/Sigma-1_receptor \"Sigma-1 receptor\") agonist, SNRI, NDRI, other actions\n- [Flupentixol\/melitracen](https:\/\/en.wikipedia.org\/wiki\/Flupentixol\/melitracen \"Flupentixol\/melitracen\") (Deanxit) – TCA and typical antipsychotic combination\n- [Olanzapine\/fluoxetine](https:\/\/en.wikipedia.org\/wiki\/Olanzapine\/fluoxetine \"Olanzapine\/fluoxetine\") (Symbyax) – SSRI and atypical antipsychotic combination – approved as a monotherapy for bipolar depression and treatment-resistant depression\n- [Tranylcypromine\/trifluoperazine](https:\/\/en.wikipedia.org\/wiki\/Tranylcypromine\/trifluoperazine \"Tranylcypromine\/trifluoperazine\") (Parstelin, Parmodalin, Jatrosom N, Stelapar) – MAOI and typical antipsychotic combination\n\n## See also\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=43 \"Edit section: See also\")\\]\n\n- [List of investigational antidepressants](https:\/\/en.wikipedia.org\/wiki\/List_of_investigational_antidepressants \"List of investigational antidepressants\")\n\n## References\n\\[[edit](https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&action=edit&section=44 \"Edit section: References\")\\]\n\n1. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-Tatsumi1997_1-0)**\n   Tatsumi M, Groshan K, Blakely RD, Richelson E (December 1997). \"Pharmacological profile of antidepressants and related compounds at human monoamine transporters\". *European Journal of Pharmacology*. **340** (2–3\\): 249–258\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1016\/s0014-2999(97)01393-9](https:\/\/doi.org\/10.1016%2Fs0014-2999%2897%2901393-9). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [9537821](https:\/\/pubmed.ncbi.nlm.nih.gov\/9537821).\n2. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid29630286_2-0)**\n   Fedder D, Patel H, Saadabadi A (March 2023). [\"Atomoxetine\"](https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK493234\/). *StatPearls \\[Internet\\]*. Treasure Island (FL): StatPearls Publishing. [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [29630286](https:\/\/pubmed.ncbi.nlm.nih.gov\/29630286).\n3. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid21155988_3-0)**\n   Dell'Osso B, Palazzo MC, Oldani L, Altamura AC (December 2011). [\"The noradrenergic action in antidepressant treatments: pharmacological and clinical aspects\"](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6493872). *CNS Neurosci Ther*. **17** (6): 723–32\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1111\/j.1755-5949.2010.00217.x](https:\/\/doi.org\/10.1111%2Fj.1755-5949.2010.00217.x). [PMC](https:\/\/en.wikipedia.org\/wiki\/PMC_\\(identifier\\) \"PMC (identifier)\") [6493872](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6493872). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [21155988](https:\/\/pubmed.ncbi.nlm.nih.gov\/21155988).\n4. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid19752841_4-0)**\n   Fleurence R, Williamson R, Jing Y, Kim E, Tran QV, Pikalov AS, et al. (2009). \"A systematic review of augmentation strategies for patients with major depressive disorder\". *Psychopharmacol Bull*. **42** (3): 57–90\\. [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [19752841](https:\/\/pubmed.ncbi.nlm.nih.gov\/19752841).\n5. ^ [***a***](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid25295426_5-0) [***b***](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid25295426_5-1)\n   Corp SA, Gitlin MJ, Altshuler LL (September 2014). \"A review of the use of stimulants and stimulant alternatives in treating bipolar depression and major depressive disorder\". *J Clin Psychiatry*. **75** (9): 1010–8\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.4088\/JCP.13r08851](https:\/\/doi.org\/10.4088%2FJCP.13r08851). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [25295426](https:\/\/pubmed.ncbi.nlm.nih.gov\/25295426).\n6. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid19897080_6-0)**\n   Arias HR, Santamaría A, Ali SF (2009). \"Pharmacological and neurotoxicological actions mediated by bupropion and diethylpropion\". *Int. Rev. Neurobiol*. International Review of Neurobiology. **88**: 223–55\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1016\/S0074-7742(09)88009-4](https:\/\/doi.org\/10.1016%2FS0074-7742%2809%2988009-4). [ISBN](https:\/\/en.wikipedia.org\/wiki\/ISBN_\\(identifier\\) \"ISBN (identifier)\")\n   \n   [9780123745040](https:\/\/en.wikipedia.org\/wiki\/Special:BookSources\/9780123745040 \"Special:BookSources\/9780123745040\")\n   \n   . [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [19897080](https:\/\/pubmed.ncbi.nlm.nih.gov\/19897080).\n7. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid25813654_7-0)**\n   Dale E, Bang-Andersen B, Sánchez C (2015). [\"Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs\"](https:\/\/doi.org\/10.1016%2Fj.bcp.2015.03.011). *Biochem. Pharmacol*. **95** (2): 81–97\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1016\/j.bcp.2015.03.011](https:\/\/doi.org\/10.1016%2Fj.bcp.2015.03.011). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [25813654](https:\/\/pubmed.ncbi.nlm.nih.gov\/25813654).\n8. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid10907387_8-0)**\n   Challman TD, Lipsky JJ (2000). [\"Methylphenidate: its pharmacology and uses\"](https:\/\/doi.org\/10.4065%2F75.7.711). *Mayo Clin. Proc*. **75** (7): 711–21\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.4065\/75.7.711](https:\/\/doi.org\/10.4065%2F75.7.711). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [10907387](https:\/\/pubmed.ncbi.nlm.nih.gov\/10907387).\n9. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid22144657_9-0)**\n   Prommer E (2012). \"Methylphenidate: established and expanding roles in symptom management\". *Am J Hosp Palliat Care*. **29** (6): 483–90\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1177\/1049909111427029](https:\/\/doi.org\/10.1177%2F1049909111427029). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [22144657](https:\/\/pubmed.ncbi.nlm.nih.gov\/22144657). [S2CID](https:\/\/en.wikipedia.org\/wiki\/S2CID_\\(identifier\\) \"S2CID (identifier)\") [21384037](https:\/\/api.semanticscholar.org\/CorpusID:21384037).\n10. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-AdisInsight-Amisulpride_10-0)**\n    [\"Amisulpride\"](https:\/\/adisinsight.springer.com\/drugs\/800005602). *AdisInsight*. 24 October 2021. Retrieved 22 October 2024.\n11. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-AdisInsight-Levosulpiride_11-0)**\n    [\"Levosulpiride\"](https:\/\/adisinsight.springer.com\/drugs\/800003554). *AdisInsight*. 24 October 2021. Retrieved 22 October 2024.\n12. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-Sulpiride-Japanese-Label_12-0)**\n    [\"Kusuri-no-Shiori(Drug Information Sheet)\"](https:\/\/www.rad-ar.or.jp\/siori\/english\/search\/result?n=35833). *くすりの適正使用協議会*. Retrieved 22 October 2024.\n13. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-SpravatoLabel_13-0)**\n    [\"SPRAVATO™ (esketamine) nasal spray FDA label\"](https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2019\/211243lbl.pdf) (PDF). [Food and Drug Administration](https:\/\/en.wikipedia.org\/wiki\/Food_and_Drug_Administration \"Food and Drug Administration\"). 5 March 2019. Retrieved 6 March 2019.\n14. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid26768892_14-0)**\n    Zhang MW, Harris KM, Ho RC (2016). [\"Is off-label repeat prescription of ketamine as a rapid antidepressant safe? Controversies, ethical concerns, and legal implications\"](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4714497). *BMC Med Ethics*. **17**: 4. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1186\/s12910-016-0087-3](https:\/\/doi.org\/10.1186%2Fs12910-016-0087-3). [PMC](https:\/\/en.wikipedia.org\/wiki\/PMC_\\(identifier\\) \"PMC (identifier)\") [4714497](https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4714497). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [26768892](https:\/\/pubmed.ncbi.nlm.nih.gov\/26768892).\n15. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid27514300_15-0)**\n    Thase ME (2016). \"Adverse Effects of Second-Generation Antipsychotics as Adjuncts to Antidepressants: Are the Risks Worth the Benefits?\". *Psychiatr. Clin. North Am*. **39** (3): 477–86\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1016\/j.psc.2016.04.008](https:\/\/doi.org\/10.1016%2Fj.psc.2016.04.008). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [27514300](https:\/\/pubmed.ncbi.nlm.nih.gov\/27514300).\n16. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid32447354_16-0)**\n    Urban AE, Cubała WJ (February 2020). [\"The role of eugeroics in the treatment of affective disorders\"](https:\/\/doi.org\/10.12740%2FPP%2FOnlineFirst%2F90687). *Psychiatr Pol*. **54** (1): 21–33\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.12740\/PP\/OnlineFirst\/90687](https:\/\/doi.org\/10.12740%2FPP%2FOnlineFirst%2F90687). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [32447354](https:\/\/pubmed.ncbi.nlm.nih.gov\/32447354).\n17. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid28318897_17-0)**\n    Kleeblatt J, Betzler F, Kilarski LL, Bschor T, Köhler S (May 2017). \"Efficacy of off-label augmentation in unipolar depression: A systematic review of the evidence\". *Eur Neuropsychopharmacol*. **27** (5): 423–441\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1016\/j.euroneuro.2017.03.003](https:\/\/doi.org\/10.1016%2Fj.euroneuro.2017.03.003). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [28318897](https:\/\/pubmed.ncbi.nlm.nih.gov\/28318897). [S2CID](https:\/\/en.wikipedia.org\/wiki\/S2CID_\\(identifier\\) \"S2CID (identifier)\") [3740987](https:\/\/api.semanticscholar.org\/CorpusID:3740987).\n18. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid31643130_18-0)**\n    Nunez NA, Singh B, Romo-Nava F, Joseph B, Veldic M, Cuellar-Barboza A, et al. (March 2020). [\"Efficacy and tolerability of adjunctive modafinil\/armodafinil in bipolar depression: A meta-analysis of randomized controlled trials\"](https:\/\/doi.org\/10.1111%2Fbdi.12859). *Bipolar Disord*. **22** (2): 109–120\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1111\/bdi.12859](https:\/\/doi.org\/10.1111%2Fbdi.12859). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [31643130](https:\/\/pubmed.ncbi.nlm.nih.gov\/31643130).\n19. **[^](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants#cite_ref-pmid28256707_19-0)**\n    Szmulewicz AG, Angriman F, Samamé C, Ferraris A, Vigo D, Strejilevich SA (June 2017). \"Dopaminergic agents in the treatment of bipolar depression: a systematic review and meta-analysis\". *Acta Psychiatr Scand*. **135** (6): 527–538\\. [doi](https:\/\/en.wikipedia.org\/wiki\/Doi_\\(identifier\\) \"Doi (identifier)\"):[10\\.1111\/acps.12712](https:\/\/doi.org\/10.1111%2Facps.12712). [PMID](https:\/\/en.wikipedia.org\/wiki\/PMID_\\(identifier\\) \"PMID (identifier)\") [28256707](https:\/\/pubmed.ncbi.nlm.nih.gov\/28256707). [S2CID](https:\/\/en.wikipedia.org\/wiki\/S2CID_\\(identifier\\) \"S2CID (identifier)\") [3712257](https:\/\/api.semanticscholar.org\/CorpusID:3712257).\n\n| [v](https:\/\/en.wikipedia.org\/wiki\/Template:Antidepressants \"Template:Antidepressants\") [t](https:\/\/en.wikipedia.org\/wiki\/Template_talk:Antidepressants \"Template talk:Antidepressants\") [e](https:\/\/en.wikipedia.org\/wiki\/Special:EditPage\/Template:Antidepressants \"Special:EditPage\/Template:Antidepressants\")[Antidepressants](https:\/\/en.wikipedia.org\/wiki\/Antidepressant \"Antidepressant\") ([N06A](https:\/\/en.wikipedia.org\/wiki\/ATC_code_N06#N06A \"ATC code N06\")) |   |\n|---|---|\n| Specific [reuptake inhibitors](https:\/\/en.wikipedia.org\/wiki\/Reuptake_inhibitor \"Reuptake inhibitor\") or [receptor modulators](https:\/\/en.wikipedia.org\/wiki\/Receptor_modulator \"Receptor modulator\") |   |\n|   |   |\n| [SSRIs](https:\/\/en.wikipedia.org\/wiki\/Selective_serotonin_reuptake_inhibitors \"Selective serotonin reuptake inhibitors\")Tooltip Selective serotonin reuptake inhibitors | [Citalopram](https:\/\/en.wikipedia.org\/wiki\/Citalopram \"Citalopram\") [Escitalopram](https:\/\/en.wikipedia.org\/wiki\/Escitalopram \"Escitalopram\") [Fluoxetine](https:\/\/en.wikipedia.org\/wiki\/Fluoxetine \"Fluoxetine\")\\# [Fluvoxamine](https:\/\/en.wikipedia.org\/wiki\/Fluvoxamine \"Fluvoxamine\") [Indalpine](https:\/\/en.wikipedia.org\/wiki\/Indalpine \"Indalpine\")‡ [Paroxetine](https:\/\/en.wikipedia.org\/wiki\/Paroxetine \"Paroxetine\") [Sertraline](https:\/\/en.wikipedia.org\/wiki\/Sertraline \"Sertraline\") [Zimelidine](https:\/\/en.wikipedia.org\/wiki\/Zimelidine \"Zimelidine\")‡ |\n| [SNRIs](https:\/\/en.wikipedia.org\/wiki\/Serotonin%E2%80%93norepinephrine_reuptake_inhibitors \"Serotonin–norepinephrine reuptake inhibitors\")Tooltip Serotonin–norepinephrine reuptake inhibitors | [Desvenlafaxine](https:\/\/en.wikipedia.org\/wiki\/Desvenlafaxine \"Desvenlafaxine\") [Duloxetine](https:\/\/en.wikipedia.org\/wiki\/Duloxetine \"Duloxetine\") [Levomilnacipran](https:\/\/en.wikipedia.org\/wiki\/Levomilnacipran \"Levomilnacipran\") [Milnacipran](https:\/\/en.wikipedia.org\/wiki\/Milnacipran \"Milnacipran\") [Tofenacin](https:\/\/en.wikipedia.org\/wiki\/Tofenacin \"Tofenacin\") [Venlafaxine](https:\/\/en.wikipedia.org\/wiki\/Venlafaxine \"Venlafaxine\") |\n| [NRIs](https:\/\/en.wikipedia.org\/wiki\/Norepinephrine_reuptake_inhibitors \"Norepinephrine reuptake inhibitors\")Tooltip Norepinephrine reuptake inhibitors | [Atomoxetine](https:\/\/en.wikipedia.org\/wiki\/Atomoxetine \"Atomoxetine\") [Reboxetine](https:\/\/en.wikipedia.org\/wiki\/Reboxetine \"Reboxetine\") [Viloxazine](https:\/\/en.wikipedia.org\/wiki\/Viloxazine \"Viloxazine\") |\n| [NDRIs](https:\/\/en.wikipedia.org\/wiki\/Norepinephrine%E2%80%93dopamine_reuptake_inhibitors \"Norepinephrine–dopamine reuptake inhibitors\")Tooltip Norepinephrine–dopamine reuptake inhibitors | [Amineptine](https:\/\/en.wikipedia.org\/wiki\/Amineptine \"Amineptine\")‡ [Bupropion](https:\/\/en.wikipedia.org\/wiki\/Bupropion \"Bupropion\") [Nomifensine](https:\/\/en.wikipedia.org\/wiki\/Nomifensine \"Nomifensine\")‡ |\n| [NaSSAs](https:\/\/en.wikipedia.org\/wiki\/Noradrenergic_and_specific_serotonergic_antidepressants \"Noradrenergic and specific serotonergic antidepressants\")Tooltip Noradrenergic and specific serotonergic antidepressants | [Mianserin](https:\/\/en.wikipedia.org\/wiki\/Mianserin \"Mianserin\") [Mirtazapine](https:\/\/en.wikipedia.org\/wiki\/Mirtazapine \"Mirtazapine\") [Setiptiline](https:\/\/en.wikipedia.org\/wiki\/Setiptiline \"Setiptiline\") |\n| [SARIs](https:\/\/en.wikipedia.org\/wiki\/Serotonin_antagonist_and_reuptake_inhibitors \"Serotonin antagonist and reuptake inhibitors\")Tooltip Serotonin antagonist and reuptake inhibitors | [Etoperidone](https:\/\/en.wikipedia.org\/wiki\/Etoperidone \"Etoperidone\") [Nefazodone](https:\/\/en.wikipedia.org\/wiki\/Nefazodone \"Nefazodone\") [Trazodone](https:\/\/en.wikipedia.org\/wiki\/Trazodone \"Trazodone\") |\n| [SMS](https:\/\/en.wikipedia.org\/wiki\/Serotonin_modulator_and_stimulators \"Serotonin modulator and stimulators\")Tooltip Serotonin modulator and stimulators | [Vilazodone](https:\/\/en.wikipedia.org\/wiki\/Vilazodone \"Vilazodone\") [Vortioxetine](https:\/\/en.wikipedia.org\/wiki\/Vortioxetine \"Vortioxetine\") |\n| Others | [Agomelatine](https:\/\/en.wikipedia.org\/wiki\/Agomelatine \"Agomelatine\") [Amisulpride](https:\/\/en.wikipedia.org\/wiki\/Amisulpride \"Amisulpride\") [Dextromethorphan\/bupropion](https:\/\/en.wikipedia.org\/wiki\/Dextromethorphan\/bupropion \"Dextromethorphan\/bupropion\") [Esketamine](https:\/\/en.wikipedia.org\/wiki\/Esketamine \"Esketamine\") [Etryptamine](https:\/\/en.wikipedia.org\/wiki\/Alpha-Ethyltryptamine \"Alpha-Ethyltryptamine\")‡ [Gepirone](https:\/\/en.wikipedia.org\/wiki\/Gepirone \"Gepirone\") [Indeloxazine](https:\/\/en.wikipedia.org\/wiki\/Indeloxazine \"Indeloxazine\") [Flupentixol](https:\/\/en.wikipedia.org\/wiki\/Flupentixol \"Flupentixol\") [Ketamine](https:\/\/en.wikipedia.org\/wiki\/Ketamine \"Ketamine\")§ [Medifoxamine](https:\/\/en.wikipedia.org\/wiki\/Medifoxamine \"Medifoxamine\")‡ [Metryptamine](https:\/\/en.wikipedia.org\/wiki\/Alpha-Methyltryptamine \"Alpha-Methyltryptamine\")‡ [Oxaflozane](https:\/\/en.wikipedia.org\/wiki\/Oxaflozane \"Oxaflozane\")‡ [Pivagabine](https:\/\/en.wikipedia.org\/wiki\/Pivagabine \"Pivagabine\")‡ [Tandospirone](https:\/\/en.wikipedia.org\/wiki\/Tandospirone \"Tandospirone\") [Teniloxazine](https:\/\/en.wikipedia.org\/wiki\/Teniloxazine \"Teniloxazine\") [Tianeptine](https:\/\/en.wikipedia.org\/wiki\/Tianeptine \"Tianeptine\") |\n| [Tricyclic](https:\/\/en.wikipedia.org\/wiki\/Tricyclic \"Tricyclic\") and [tetracyclic antidepressants](https:\/\/en.wikipedia.org\/wiki\/Tetracyclic_antidepressant \"Tetracyclic antidepressant\") |   |\n|   |   |\n| [TCAs](https:\/\/en.wikipedia.org\/wiki\/Tricyclic_antidepressants \"Tricyclic antidepressants\")Tooltip Tricyclic antidepressants | [Amineptine](https:\/\/en.wikipedia.org\/wiki\/Amineptine \"Amineptine\")‡ [Amitriptyline](https:\/\/en.wikipedia.org\/wiki\/Amitriptyline \"Amitriptyline\")\\# [Amitriptylinoxide](https:\/\/en.wikipedia.org\/wiki\/Amitriptylinoxide \"Amitriptylinoxide\") [Amoxapine](https:\/\/en.wikipedia.org\/wiki\/Amoxapine \"Amoxapine\") [Butriptyline](https:\/\/en.wikipedia.org\/wiki\/Butriptyline \"Butriptyline\")‡ [Clomipramine](https:\/\/en.wikipedia.org\/wiki\/Clomipramine \"Clomipramine\")\\# [Demexiptiline](https:\/\/en.wikipedia.org\/wiki\/Demexiptiline \"Demexiptiline\")‡ [Desipramine](https:\/\/en.wikipedia.org\/wiki\/Desipramine \"Desipramine\") [Dibenzepin](https:\/\/en.wikipedia.org\/wiki\/Dibenzepin \"Dibenzepin\") [Dimetacrine](https:\/\/en.wikipedia.org\/wiki\/Dimetacrine \"Dimetacrine\")‡ [Dosulepin](https:\/\/en.wikipedia.org\/wiki\/Dosulepin \"Dosulepin\") [Doxepin](https:\/\/en.wikipedia.org\/wiki\/Doxepin \"Doxepin\") [Imipramine](https:\/\/en.wikipedia.org\/wiki\/Imipramine \"Imipramine\") [Imipraminoxide](https:\/\/en.wikipedia.org\/wiki\/Imipraminoxide \"Imipraminoxide\")‡ [Iprindole](https:\/\/en.wikipedia.org\/wiki\/Iprindole \"Iprindole\")‡ [Lofepramine](https:\/\/en.wikipedia.org\/wiki\/Lofepramine \"Lofepramine\") [Melitracen](https:\/\/en.wikipedia.org\/wiki\/Melitracen \"Melitracen\") [Metapramine](https:\/\/en.wikipedia.org\/wiki\/Metapramine \"Metapramine\")‡ [Nitroxazepine](https:\/\/en.wikipedia.org\/wiki\/Nitroxazepine \"Nitroxazepine\") [Nortriptyline](https:\/\/en.wikipedia.org\/wiki\/Nortriptyline \"Nortriptyline\") [Noxiptiline](https:\/\/en.wikipedia.org\/wiki\/Noxiptiline \"Noxiptiline\") [Opipramol](https:\/\/en.wikipedia.org\/wiki\/Opipramol \"Opipramol\") [Pipofezine](https:\/\/en.wikipedia.org\/wiki\/Pipofezine \"Pipofezine\") [Propizepine](https:\/\/en.wikipedia.org\/wiki\/Propizepine \"Propizepine\")‡ [Protriptyline](https:\/\/en.wikipedia.org\/wiki\/Protriptyline \"Protriptyline\") [Quinupramine](https:\/\/en.wikipedia.org\/wiki\/Quinupramine \"Quinupramine\")‡ [Tianeptine](https:\/\/en.wikipedia.org\/wiki\/Tianeptine \"Tianeptine\") [Trimipramine](https:\/\/en.wikipedia.org\/wiki\/Trimipramine \"Trimipramine\") |\n| [TeCAs](https:\/\/en.wikipedia.org\/wiki\/Tetracyclic_antidepressants \"Tetracyclic antidepressants\")Tooltip Tetracyclic antidepressants | [Maprotiline](https:\/\/en.wikipedia.org\/wiki\/Maprotiline \"Maprotiline\") [Mianserin](https:\/\/en.wikipedia.org\/wiki\/Mianserin \"Mianserin\") [Mirtazapine](https:\/\/en.wikipedia.org\/wiki\/Mirtazapine \"Mirtazapine\") [Setiptiline](https:\/\/en.wikipedia.org\/wiki\/Setiptiline \"Setiptiline\") |\n| Others | [Tiazesim](https:\/\/en.wikipedia.org\/wiki\/Tiazesim \"Tiazesim\") |\n| [Monoamine oxidase inhibitors](https:\/\/en.wikipedia.org\/wiki\/Monoamine_oxidase_inhibitor \"Monoamine oxidase inhibitor\") |   |\n|   |   |\n| Non-selective | *Irreversible:* [Benmoxin](https:\/\/en.wikipedia.org\/wiki\/Benmoxin \"Benmoxin\")‡ [Iproclozide](https:\/\/en.wikipedia.org\/wiki\/Iproclozide \"Iproclozide\")‡ [Iproniazid](https:\/\/en.wikipedia.org\/wiki\/Iproniazid \"Iproniazid\")‡ [Isocarboxazid](https:\/\/en.wikipedia.org\/wiki\/Isocarboxazid \"Isocarboxazid\") [Isoniazid](https:\/\/en.wikipedia.org\/wiki\/Isoniazid \"Isoniazid\")\\# [Linezolid](https:\/\/en.wikipedia.org\/wiki\/Linezolid \"Linezolid\")\\# [Mebanazine](https:\/\/en.wikipedia.org\/wiki\/Mebanazine \"Mebanazine\")‡ [Nialamide](https:\/\/en.wikipedia.org\/wiki\/Nialamide \"Nialamide\")‡ [Octamoxin](https:\/\/en.wikipedia.org\/wiki\/Octamoxin \"Octamoxin\")‡ [Phenelzine](https:\/\/en.wikipedia.org\/wiki\/Phenelzine \"Phenelzine\") [Pheniprazine](https:\/\/en.wikipedia.org\/wiki\/Pheniprazine \"Pheniprazine\")‡ [Phenoxypropazine](https:\/\/en.wikipedia.org\/wiki\/Phenoxypropazine \"Phenoxypropazine\")‡ [Pivhydrazine](https:\/\/en.wikipedia.org\/wiki\/Pivhydrazine \"Pivhydrazine\")‡ [Safrazine](https:\/\/en.wikipedia.org\/wiki\/Safrazine \"Safrazine\")‡ [Tedizolid](https:\/\/en.wikipedia.org\/wiki\/Tedizolid \"Tedizolid\") [Tranylcypromine](https:\/\/en.wikipedia.org\/wiki\/Tranylcypromine \"Tranylcypromine\") *Reversible:* [Caroxazone](https:\/\/en.wikipedia.org\/wiki\/Caroxazone \"Caroxazone\")‡ *Mixed:* [Bifemelane](https:\/\/en.wikipedia.org\/wiki\/Bifemelane \"Bifemelane\") |\n| [MAOA](https:\/\/en.wikipedia.org\/wiki\/Monoamine_oxidase_A \"Monoamine oxidase A\")Tooltip Monoamine oxidase A\\-selective | *Reversible:* [Eprobemide](https:\/\/en.wikipedia.org\/wiki\/Eprobemide \"Eprobemide\") [Metralindole](https:\/\/en.wikipedia.org\/wiki\/Metralindole \"Metralindole\") [Minaprine](https:\/\/en.wikipedia.org\/wiki\/Minaprine \"Minaprine\")‡ [Moclobemide](https:\/\/en.wikipedia.org\/wiki\/Moclobemide \"Moclobemide\") [Pirlindole](https:\/\/en.wikipedia.org\/wiki\/Pirlindole \"Pirlindole\") [Tetrindole](https:\/\/en.wikipedia.org\/wiki\/Tetrindole \"Tetrindole\") [Toloxatone](https:\/\/en.wikipedia.org\/wiki\/Toloxatone \"Toloxatone\") |\n| [MAOB](https:\/\/en.wikipedia.org\/wiki\/Monoamine_oxidase_B \"Monoamine oxidase B\")Tooltip Monoamine oxidase B\\-selective | *Irreversible:* [Selegiline](https:\/\/en.wikipedia.org\/wiki\/Selegiline \"Selegiline\") |\n| [Adjunctive therapies](https:\/\/en.wikipedia.org\/wiki\/Adjuvant_therapy \"Adjuvant therapy\") |   |\n| [Atypical antipsychotics](https:\/\/en.wikipedia.org\/wiki\/Atypical_antipsychotic \"Atypical antipsychotic\") ([aripiprazole](https:\/\/en.wikipedia.org\/wiki\/Aripiprazole \"Aripiprazole\"), [brexpiprazole](https:\/\/en.wikipedia.org\/wiki\/Brexpiprazole \"Brexpiprazole\"), [lurasidone](https:\/\/en.wikipedia.org\/wiki\/Lurasidone \"Lurasidone\"), [olanzapine](https:\/\/en.wikipedia.org\/wiki\/Olanzapine \"Olanzapine\"), [quetiapine](https:\/\/en.wikipedia.org\/wiki\/Quetiapine \"Quetiapine\"), [risperidone](https:\/\/en.wikipedia.org\/wiki\/Risperidone \"Risperidone\")) [Buspirone](https:\/\/en.wikipedia.org\/wiki\/Buspirone \"Buspirone\") [Lithium](https:\/\/en.wikipedia.org\/wiki\/Lithium_\\(medication\\) \"Lithium (medication)\") ([lithium carbonate](https:\/\/en.wikipedia.org\/wiki\/Lithium_carbonate \"Lithium carbonate\"), [lithium citrate](https:\/\/en.wikipedia.org\/wiki\/Lithium_citrate \"Lithium citrate\")) [Thyroid hormones](https:\/\/en.wikipedia.org\/wiki\/Thyroid_hormone \"Thyroid hormone\") ([triiodothyronine](https:\/\/en.wikipedia.org\/wiki\/Triiodothyronine \"Triiodothyronine\") (T3), [levothyroxine](https:\/\/en.wikipedia.org\/wiki\/Levothyroxine \"Levothyroxine\") (T4)) |   |\n| Miscellaneous |   |\n| [Ademetionine (SAMe)](https:\/\/en.wikipedia.org\/wiki\/Ademetionine \"Ademetionine\") [GABAkine](https:\/\/en.wikipedia.org\/wiki\/GABAA_receptor_positive_allosteric_modulator \"GABAA receptor positive allosteric modulator\") [neurosteroids](https:\/\/en.wikipedia.org\/wiki\/Neurosteroid \"Neurosteroid\") ([brexanolone](https:\/\/en.wikipedia.org\/wiki\/Allopregnanolone \"Allopregnanolone\"), [zuranolone](https:\/\/en.wikipedia.org\/wiki\/Zuranolone \"Zuranolone\")) [*Hypericum perforatum* (St. John's Wort)](https:\/\/en.wikipedia.org\/wiki\/Hypericum_perforatum \"Hypericum perforatum\") [Oxitriptan (5-HTP)](https:\/\/en.wikipedia.org\/wiki\/Oxitriptan \"Oxitriptan\") [Rubidium chloride (RbCl)](https:\/\/en.wikipedia.org\/wiki\/Rubidium_chloride \"Rubidium chloride\") [Tryptophan](https:\/\/en.wikipedia.org\/wiki\/Tryptophan \"Tryptophan\") |   |\n| \\#[WHO-EM](https:\/\/en.wikipedia.org\/wiki\/WHO_Model_List_of_Essential_Medicines \"WHO Model List of Essential Medicines\") ‡[Withdrawn](https:\/\/en.wikipedia.org\/wiki\/List_of_withdrawn_drugs \"List of withdrawn drugs\") from market [Clinical trials](https:\/\/en.wikipedia.org\/wiki\/Clinical_trial \"Clinical trial\"): †[Phase III](https:\/\/en.wikipedia.org\/wiki\/Phases_of_clinical_research#Phase_III \"Phases of clinical research\") §Never to phase III |   |\n\n| [v](https:\/\/en.wikipedia.org\/wiki\/Template:Mood_stabilizers \"Template:Mood stabilizers\") [t](https:\/\/en.wikipedia.org\/wiki\/Template_talk:Mood_stabilizers \"Template talk:Mood stabilizers\") [e](https:\/\/en.wikipedia.org\/wiki\/Special:EditPage\/Template:Mood_stabilizers \"Special:EditPage\/Template:Mood stabilizers\")[Mood stabilizers](https:\/\/en.wikipedia.org\/wiki\/Mood_stabilizer \"Mood stabilizer\") |   |\n|---|---|\n| [Anticonvulsants](https:\/\/en.wikipedia.org\/wiki\/Anticonvulsant \"Anticonvulsant\") | [Carbamazepine](https:\/\/en.wikipedia.org\/wiki\/Carbamazepine \"Carbamazepine\") [Lamotrigine](https:\/\/en.wikipedia.org\/wiki\/Lamotrigine \"Lamotrigine\") [Oxcarbazepine](https:\/\/en.wikipedia.org\/wiki\/Oxcarbazepine \"Oxcarbazepine\") [Valproate](https:\/\/en.wikipedia.org\/wiki\/Valproate \"Valproate\") [Valnoctamide](https:\/\/en.wikipedia.org\/wiki\/Valnoctamide \"Valnoctamide\") [Valproate pivoxil](https:\/\/en.wikipedia.org\/wiki\/Valproate_pivoxil \"Valproate pivoxil\") [Valpromide](https:\/\/en.wikipedia.org\/wiki\/Valpromide \"Valpromide\") |\n| [Atypical antipsychotics](https:\/\/en.wikipedia.org\/wiki\/Atypical_antipsychotic \"Atypical antipsychotic\") | [Aripiprazole](https:\/\/en.wikipedia.org\/wiki\/Aripiprazole \"Aripiprazole\") [Asenapine](https:\/\/en.wikipedia.org\/wiki\/Asenapine \"Asenapine\") [Cariprazine](https:\/\/en.wikipedia.org\/wiki\/Cariprazine \"Cariprazine\") [Clozapine](https:\/\/en.wikipedia.org\/wiki\/Clozapine \"Clozapine\") [Lurasidone](https:\/\/en.wikipedia.org\/wiki\/Lurasidone \"Lurasidone\") [Olanzapine](https:\/\/en.wikipedia.org\/wiki\/Olanzapine \"Olanzapine\") ([\\+fluoxetine](https:\/\/en.wikipedia.org\/wiki\/Olanzapine\/fluoxetine \"Olanzapine\/fluoxetine\")) [Paliperidone](https:\/\/en.wikipedia.org\/wiki\/Paliperidone \"Paliperidone\") [Quetiapine](https:\/\/en.wikipedia.org\/wiki\/Quetiapine \"Quetiapine\") [Risperidone](https:\/\/en.wikipedia.org\/wiki\/Risperidone \"Risperidone\") [Ziprasidone](https:\/\/en.wikipedia.org\/wiki\/Ziprasidone \"Ziprasidone\") |\n| Others | [Ketamine](https:\/\/en.wikipedia.org\/wiki\/Ketamine \"Ketamine\") [Lithium](https:\/\/en.wikipedia.org\/wiki\/Lithium_\\(medication\\) \"Lithium (medication)\") ([lithium acetate](https:\/\/en.wikipedia.org\/wiki\/Lithium_acetate \"Lithium acetate\"), [lithium carbonate](https:\/\/en.wikipedia.org\/wiki\/Lithium_carbonate \"Lithium carbonate\"), [lithium chloride](https:\/\/en.wikipedia.org\/wiki\/Lithium_chloride \"Lithium chloride\"), [lithium citrate](https:\/\/en.wikipedia.org\/wiki\/Lithium_citrate \"Lithium citrate\"), [lithium hydroxide](https:\/\/en.wikipedia.org\/wiki\/Lithium_hydroxide \"Lithium hydroxide\"), [lithium orotate](https:\/\/en.wikipedia.org\/wiki\/Lithium_orotate \"Lithium orotate\")) [Omega-3 fatty acids](https:\/\/en.wikipedia.org\/wiki\/Omega-3_fatty_acid \"Omega-3 fatty acid\") ([docosahexaenoic acid](https:\/\/en.wikipedia.org\/wiki\/Docosahexaenoic_acid \"Docosahexaenoic acid\"), [eicosapentaenoic acid](https:\/\/en.wikipedia.org\/wiki\/Eicosapentaenoic_acid \"Eicosapentaenoic acid\")) |\n\n![](https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1&usesul3=1)\n\nRetrieved from \"<https:\/\/en.wikipedia.org\/w\/index.php?title=List_of_antidepressants&oldid=1289313995>\"\n\n[Categories](https:\/\/en.wikipedia.org\/wiki\/Help:Category \"Help:Category\"):\n\n- [Antidepressants](https:\/\/en.wikipedia.org\/wiki\/Category:Antidepressants \"Category:Antidepressants\")\n- [Drug-related lists](https:\/\/en.wikipedia.org\/wiki\/Category:Drug-related_lists \"Category:Drug-related lists\")\n- [Mood stabilizers](https:\/\/en.wikipedia.org\/wiki\/Category:Mood_stabilizers \"Category:Mood stabilizers\")\n\nHidden categories:\n\n- [Articles with short description](https:\/\/en.wikipedia.org\/wiki\/Category:Articles_with_short_description \"Category:Articles with short description\")\n- [Short description is different from Wikidata](https:\/\/en.wikipedia.org\/wiki\/Category:Short_description_is_different_from_Wikidata \"Category:Short description is different from Wikidata\")\n\n- This page was last edited on 7 May 2025, at 20:49 (UTC).\n- Text is available under the [Creative Commons Attribution-ShareAlike 4.0 License](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:Text_of_the_Creative_Commons_Attribution-ShareAlike_4.0_International_License \"Wikipedia:Text of the Creative Commons Attribution-ShareAlike 4.0 International License\"); additional terms may apply. By using this site, you agree to the [Terms of Use](https:\/\/foundation.wikimedia.org\/wiki\/Special:MyLanguage\/Policy:Terms_of_Use \"foundation:Special:MyLanguage\/Policy:Terms of Use\") and [Privacy Policy](https:\/\/foundation.wikimedia.org\/wiki\/Special:MyLanguage\/Policy:Privacy_policy \"foundation:Special:MyLanguage\/Policy:Privacy policy\"). Wikipedia® is a registered trademark of the [Wikimedia Foundation, Inc.](https:\/\/wikimediafoundation.org\/), a non-profit organization.\n\n- [Privacy policy](https:\/\/foundation.wikimedia.org\/wiki\/Special:MyLanguage\/Policy:Privacy_policy)\n- [About Wikipedia](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:About)\n- [Disclaimers](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:General_disclaimer)\n- [Contact Wikipedia](https:\/\/en.wikipedia.org\/wiki\/Wikipedia:Contact_us)\n- [Code of Conduct](https:\/\/foundation.wikimedia.org\/wiki\/Special:MyLanguage\/Policy:Universal_Code_of_Conduct)\n- [Developers](https:\/\/developer.wikimedia.org\/)\n- [Statistics](https:\/\/stats.wikimedia.org\/#\/en.wikipedia.org)\n- [Cookie statement](https:\/\/foundation.wikimedia.org\/wiki\/Special:MyLanguage\/Policy:Cookie_statement)\n- [Mobile view](https:\/\/en.m.wikipedia.org\/w\/index.php?title=List_of_antidepressants&mobileaction=toggle_view_mobile)\n\n- [![Wikimedia Foundation](https:\/\/en.wikipedia.org\/static\/images\/footer\/wikimedia.svg)](https:\/\/www.wikimedia.org\/)\n- [![Powered by MediaWiki](https:\/\/en.wikipedia.org\/w\/resources\/assets\/mediawiki_compact.svg)](https:\/\/www.mediawiki.org\/)\n\nSearch\n\nToggle the table of contents\n\nList of antidepressants\n\n2 languages\n\n[Add topic](https:\/\/en.wikipedia.org\/wiki\/List_of_antidepressants)","attrs_readable_markdown":null,"meta_canonical":null}

3. Robots.txt Check

Query:

Response:

4. Spam/Ban Check

Query:

Response:

5. Seen Status Check

ℹ️ Skipped - page is already crawled

📄

INDEXABLE

✅

CRAWLED

8 months ago

🤖

ROBOTS ALLOWED

Page Info Filters

Filter	Status	Condition	Details
HTTP status	PASS	`download_http_code = 200`	HTTP 200
Age cutoff	PASS	`download_stamp > now() - 6 MONTH`	8.1 months ago (distributed domain, exempt)
History drop	PASS	`isNull(history_drop_reason)`	No drop reason
Spam/ban	PASS	`fh_dont_index != 1 AND ml_spam_score = 0`	ml_spam_score=0
Canonical	PASS	`meta_canonical IS NULL OR = '' OR = src_unparsed`	Not set

Page Details

Property	Value
URL	https://en.wikipedia.org/wiki/List_of_antidepressants
Last Crawled	2025-08-06 14:05:58 (8 months ago)
First Indexed	not set
HTTP Status Code	200
Meta Title	List of antidepressants - Wikipedia
Meta Description	null
Meta Canonical	null
Boilerpipe Text	null
Markdown	[Jump to content](https://en.wikipedia.org/wiki/List_of_antidepressants#bodyContent) Main menu Main menu move to sidebar hide Navigation - [Main page](https://en.wikipedia.org/wiki/Main_Page "Visit the main page [z]") - [Contents](https://en.wikipedia.org/wiki/Wikipedia:Contents "Guides to browsing Wikipedia") - [Current events](https://en.wikipedia.org/wiki/Portal:Current_events "Articles related to current events") - [Random article](https://en.wikipedia.org/wiki/Special:Random "Visit a randomly selected article [x]") - [About Wikipedia](https://en.wikipedia.org/wiki/Wikipedia:About "Learn about Wikipedia and how it works") - [Contact us](https://en.wikipedia.org/wiki/Wikipedia:Contact_us "How to contact Wikipedia") Contribute - [Help](https://en.wikipedia.org/wiki/Help:Contents "Guidance on how to use and edit Wikipedia") - [Learn to edit](https://en.wikipedia.org/wiki/Help:Introduction "Learn how to edit Wikipedia") - [Community portal](https://en.wikipedia.org/wiki/Wikipedia:Community_portal "The hub for editors") - [Recent changes](https://en.wikipedia.org/wiki/Special:RecentChanges "A list of recent changes to Wikipedia [r]") - [Upload file](https://en.wikipedia.org/wiki/Wikipedia:File_upload_wizard "Add images or other media for use on Wikipedia") - [Special pages](https://en.wikipedia.org/wiki/Special:SpecialPages) [![](https://en.wikipedia.org/static/images/icons/wikipedia.png) ![Wikipedia](https://en.wikipedia.org/static/images/mobile/copyright/wikipedia-wordmark-en.svg) ![The Free Encyclopedia](https://en.wikipedia.org/static/images/mobile/copyright/wikipedia-tagline-en.svg)](https://en.wikipedia.org/wiki/Main_Page) [Search](https://en.wikipedia.org/wiki/Special:Search "Search Wikipedia [f]") Appearance - [Donate](https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en) - [Create account](https://en.wikipedia.org/w/index.php?title=Special:CreateAccount&returnto=List+of+antidepressants "You are encouraged to create an account and log in; however, it is not mandatory") - [Log in](https://en.wikipedia.org/w/index.php?title=Special:UserLogin&returnto=List+of+antidepressants "You're encouraged to log in; however, it's not mandatory. [o]") Personal tools - [Donate](https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=en.wikipedia.org&uselang=en) - [Create account](https://en.wikipedia.org/w/index.php?title=Special:CreateAccount&returnto=List+of+antidepressants "You are encouraged to create an account and log in; however, it is not mandatory") - [Log in](https://en.wikipedia.org/w/index.php?title=Special:UserLogin&returnto=List+of+antidepressants "You're encouraged to log in; however, it's not mandatory. [o]") Pages for logged out editors [learn more](https://en.wikipedia.org/wiki/Help:Introduction) - [Contributions](https://en.wikipedia.org/wiki/Special:MyContributions "A list of edits made from this IP address [y]") - [Talk](https://en.wikipedia.org/wiki/Special:MyTalk "Discussion about edits from this IP address [n]") ## Contents move to sidebar hide - [(Top)](https://en.wikipedia.org/wiki/List_of_antidepressants) - [1 Selective serotonin reuptake inhibitors (SSRIs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Selective_serotonin_reuptake_inhibitors_\(SSRIs\)) Toggle Selective serotonin reuptake inhibitors (SSRIs) subsection - [1\.1 Discontinued/withdrawn](https://en.wikipedia.org/wiki/List_of_antidepressants#Discontinued/withdrawn) - [2 Serotonin–norepinephrine reuptake inhibitors (SNRIs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Serotonin%E2%80%93norepinephrine_reuptake_inhibitors_\(SNRIs\)) - [3 Serotonin–dopamine reuptake inhibitor (SDRIs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Serotonin%E2%80%93dopamine_reuptake_inhibitor_\(SDRIs\)) Toggle Serotonin–dopamine reuptake inhibitor (SDRIs) subsection - [3\.1 Discontinued/withdrawn](https://en.wikipedia.org/wiki/List_of_antidepressants#Discontinued/withdrawn_2) - [4 Serotonin–norepinephrine–dopamine reuptake inhibitors (SNDRIs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Serotonin%E2%80%93norepinephrine%E2%80%93dopamine_reuptake_inhibitors_\(SNDRIs\)) - [5 Serotonin modulators and stimulators (SMSs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Serotonin_modulators_and_stimulators_\(SMSs\)) - [6 Serotonin antagonist and reuptake inhibitors (SARIs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Serotonin_antagonist_and_reuptake_inhibitors_\(SARIs\)) Toggle Serotonin antagonist and reuptake inhibitors (SARIs) subsection - [6\.1 Discontinued/withdrawn](https://en.wikipedia.org/wiki/List_of_antidepressants#Discontinued/withdrawn_3) - [7 Norepinephrine reuptake inhibitors (NRIs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Norepinephrine_reuptake_inhibitors_\(NRIs\)) Toggle Norepinephrine reuptake inhibitors (NRIs) subsection - [7\.1 Off-label only](https://en.wikipedia.org/wiki/List_of_antidepressants#Off-label_only) - [8 Norepinephrine–dopamine reuptake inhibitors (NDRIs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Norepinephrine%E2%80%93dopamine_reuptake_inhibitors_\(NDRIs\)) Toggle Norepinephrine–dopamine reuptake inhibitors (NDRIs) subsection - [8\.1 Off-label only](https://en.wikipedia.org/wiki/List_of_antidepressants#Off-label_only_2) - [8\.2 Discontinued/withdrawn](https://en.wikipedia.org/wiki/List_of_antidepressants#Discontinued/withdrawn_4) - [9 Tricyclic antidepressants (TCAs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Tricyclic_antidepressants_\(TCAs\)) Toggle Tricyclic antidepressants (TCAs) subsection - [9\.1 Discontinued/withdrawn](https://en.wikipedia.org/wiki/List_of_antidepressants#Discontinued/withdrawn_5) - [10 Tetracyclic antidepressants (TeCAs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Tetracyclic_antidepressants_\(TeCAs\)) - [11 Monoamine oxidase inhibitors (MAOIs)](https://en.wikipedia.org/wiki/List_of_antidepressants#Monoamine_oxidase_inhibitors_\(MAOIs\)) Toggle Monoamine oxidase inhibitors (MAOIs) subsection - [11\.1 Irreversible](https://en.wikipedia.org/wiki/List_of_antidepressants#Irreversible) - [11\.1.1 Non-selective](https://en.wikipedia.org/wiki/List_of_antidepressants#Non-selective) - [11\.1.2 Selective for MAO-B](https://en.wikipedia.org/wiki/List_of_antidepressants#Selective_for_MAO-B) - [11\.2 Reversible](https://en.wikipedia.org/wiki/List_of_antidepressants#Reversible) - [11\.2.1 Non-selective](https://en.wikipedia.org/wiki/List_of_antidepressants#Non-selective_2) - [11\.2.2 Selective for MAO-A](https://en.wikipedia.org/wiki/List_of_antidepressants#Selective_for_MAO-A) - [11\.3 Mixed](https://en.wikipedia.org/wiki/List_of_antidepressants#Mixed) - [11\.3.1 Non-selective](https://en.wikipedia.org/wiki/List_of_antidepressants#Non-selective_3) - [12 Atypical antipsychotics](https://en.wikipedia.org/wiki/List_of_antidepressants#Atypical_antipsychotics) - [13 Others](https://en.wikipedia.org/wiki/List_of_antidepressants#Others) Toggle Others subsection - [13\.1 Marketed](https://en.wikipedia.org/wiki/List_of_antidepressants#Marketed) - [13\.2 Off-label only](https://en.wikipedia.org/wiki/List_of_antidepressants#Off-label_only_3) - [13\.3 Discontinued/withdrawn](https://en.wikipedia.org/wiki/List_of_antidepressants#Discontinued/withdrawn_6) - [13\.4 Over-the-counter](https://en.wikipedia.org/wiki/List_of_antidepressants#Over-the-counter) - [14 Adjunctive treatments](https://en.wikipedia.org/wiki/List_of_antidepressants#Adjunctive_treatments) Toggle Adjunctive treatments subsection - [14\.1 Atypical antipsychotics](https://en.wikipedia.org/wiki/List_of_antidepressants#Atypical_antipsychotics_2) - [14\.1.1 Off-label only](https://en.wikipedia.org/wiki/List_of_antidepressants#Off-label_only_4) - [14\.2 Typical antipsychotics](https://en.wikipedia.org/wiki/List_of_antidepressants#Typical_antipsychotics) - [14\.2.1 Off-label only](https://en.wikipedia.org/wiki/List_of_antidepressants#Off-label_only_5) - [14\.3 Dopamine reuptake inhibitor](https://en.wikipedia.org/wiki/List_of_antidepressants#Dopamine_reuptake_inhibitor) - [14\.3.1 Off-label only](https://en.wikipedia.org/wiki/List_of_antidepressants#Off-label_only_6) - [14\.4 Others](https://en.wikipedia.org/wiki/List_of_antidepressants#Others_2) - [14\.4.1 Off-label only](https://en.wikipedia.org/wiki/List_of_antidepressants#Off-label_only_7) - [15 Combination products](https://en.wikipedia.org/wiki/List_of_antidepressants#Combination_products) - [16 See also](https://en.wikipedia.org/wiki/List_of_antidepressants#See_also) - [17 References](https://en.wikipedia.org/wiki/List_of_antidepressants#References) Toggle the table of contents # List of antidepressants 2 languages - [Português](https://pt.wikipedia.org/wiki/Lista_de_antidepressivos "Lista de antidepressivos – Portuguese") - [سنڌي](https://sd.wikipedia.org/wiki/%D8%A7%D9%8A%D9%86%D9%BD%D9%8A_%DA%8A%D9%BE%D8%B1%D9%8A%D8%B4%D9%86_%D8%AF%D9%88%D8%A7%D8%A6%D9%86_%D8%AC%D9%8A_%D9%81%D9%87%D8%B1%D8%B3%D8%AA "اينٽي ڊپريشن دوائن جي فهرست – Sindhi") [Edit links](https://www.wikidata.org/wiki/Special:EntityPage/Q6606027#sitelinks-wikipedia "Edit interlanguage links") - [Article](https://en.wikipedia.org/wiki/List_of_antidepressants "View the content page [c]") - [Talk](https://en.wikipedia.org/wiki/Talk:List_of_antidepressants "Discuss improvements to the content page [t]") English - [Read](https://en.wikipedia.org/wiki/List_of_antidepressants) - [Edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit "Edit this page [e]") - [View history](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=history "Past revisions of this page [h]") Tools Tools move to sidebar hide Actions - [Read](https://en.wikipedia.org/wiki/List_of_antidepressants) - [Edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit "Edit this page [e]") - [View history](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=history) General - [What links here](https://en.wikipedia.org/wiki/Special:WhatLinksHere/List_of_antidepressants "List of all English Wikipedia pages containing links to this page [j]") - [Related changes](https://en.wikipedia.org/wiki/Special:RecentChangesLinked/List_of_antidepressants "Recent changes in pages linked from this page [k]") - [Upload file](https://en.wikipedia.org/wiki/Wikipedia:File_Upload_Wizard "Upload files [u]") - [Permanent link](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&oldid=1289313995 "Permanent link to this revision of this page") - [Page information](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=info "More information about this page") - [Cite this page](https://en.wikipedia.org/w/index.php?title=Special:CiteThisPage&page=List_of_antidepressants&id=1289313995&wpFormIdentifier=titleform "Information on how to cite this page") - [Get shortened URL](https://en.wikipedia.org/w/index.php?title=Special:UrlShortener&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FList_of_antidepressants) - [Download QR code](https://en.wikipedia.org/w/index.php?title=Special:QrCode&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FList_of_antidepressants) Print/export - [Download as PDF](https://en.wikipedia.org/w/index.php?title=Special:DownloadAsPdf&page=List_of_antidepressants&action=show-download-screen "Download this page as a PDF file") - [Printable version](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&printable=yes "Printable version of this page [p]") In other projects - [Wikidata item](https://www.wikidata.org/wiki/Special:EntityPage/Q6606027 "Structured data on this page hosted by Wikidata [g]") Appearance move to sidebar hide From Wikipedia, the free encyclopedia This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment [antidepressants](https://en.wikipedia.org/wiki/Antidepressant "Antidepressant") or [mood stabilizers](https://en.wikipedia.org/wiki/Mood_stabilizer "Mood stabilizer"), by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses. All drugs listed are approved specifically for [major depressive disorder](https://en.wikipedia.org/wiki/Major_depressive_disorder "Major depressive disorder") unless noted otherwise. ## Selective serotonin reuptake inhibitors (SSRIs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=1 "Edit section: Selective serotonin reuptake inhibitors (SSRIs)")\] [Selective serotonin reuptake inhibitors](https://en.wikipedia.org/wiki/Selective_serotonin_reuptake_inhibitor "Selective serotonin reuptake inhibitor") include: - [Citalopram](https://en.wikipedia.org/wiki/Citalopram "Citalopram") (Celexa, Cipramil) - [Escitalopram](https://en.wikipedia.org/wiki/Escitalopram "Escitalopram") (Lexapro, Cipralex) - [Fluoxetine](https://en.wikipedia.org/wiki/Fluoxetine "Fluoxetine") (Prozac, Sarafem) - [Fluvoxamine](https://en.wikipedia.org/wiki/Fluvoxamine "Fluvoxamine") (Luvox, Faverin) - [Paroxetine](https://en.wikipedia.org/wiki/Paroxetine "Paroxetine") (Paxil, Seroxat) - [Sertraline](https://en.wikipedia.org/wiki/Sertraline "Sertraline") (Zoloft, Lustral) ### Discontinued/withdrawn \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=2 "Edit section: Discontinued/withdrawn")\] - [Indalpine](https://en.wikipedia.org/wiki/Indalpine "Indalpine") (Upstene) - [Zimelidine](https://en.wikipedia.org/wiki/Zimelidine "Zimelidine") (Normud, Zelmid) ## Serotonin–norepinephrine reuptake inhibitors (SNRIs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=3 "Edit section: Serotonin–norepinephrine reuptake inhibitors (SNRIs)")\] [Serotonin–norepinephrine reuptake inhibitors](https://en.wikipedia.org/wiki/Serotonin%E2%80%93norepinephrine_reuptake_inhibitor "Serotonin–norepinephrine reuptake inhibitor") include: - [Desvenlafaxine](https://en.wikipedia.org/wiki/Desvenlafaxine "Desvenlafaxine") (Pristiq) - [Duloxetine](https://en.wikipedia.org/wiki/Duloxetine "Duloxetine") (Cymbalta) - [Levomilnacipran](https://en.wikipedia.org/wiki/Levomilnacipran "Levomilnacipran") (Fetzima) - [Milnacipran](https://en.wikipedia.org/wiki/Milnacipran "Milnacipran") (Ixel, Savella, Milnaneurax) - [Venlafaxine](https://en.wikipedia.org/wiki/Venlafaxine "Venlafaxine") (Effexor, Trevilor) ## Serotonin–dopamine reuptake inhibitor (SDRIs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=4 "Edit section: Serotonin–dopamine reuptake inhibitor (SDRIs)")\] [Serotonin–dopamine reuptake inhibitors](https://en.wikipedia.org/wiki/Serotonin%E2%80%93dopamine_reuptake_inhibitor "Serotonin–dopamine reuptake inhibitor") include: None currently marketed ### Discontinued/withdrawn \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=5 "Edit section: Discontinued/withdrawn")\] - [Medifoxamine](https://en.wikipedia.org/wiki/Medifoxamine "Medifoxamine") (Clédial, Gerdaxyl) ## Serotonin–norepinephrine–dopamine reuptake inhibitors (SNDRIs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=6 "Edit section: Serotonin–norepinephrine–dopamine reuptake inhibitors (SNDRIs)")\] [Serotonin–norepinephrine–dopamine reuptake inhibitors](https://en.wikipedia.org/wiki/Serotonin%E2%80%93norepinephrine%E2%80%93dopamine_reuptake_inhibitor "Serotonin–norepinephrine–dopamine reuptake inhibitor") include: - [Toludesvenlafaxine](https://en.wikipedia.org/wiki/Toludesvenlafaxine "Toludesvenlafaxine") (Ruoxinlin) - [Nefazodone](https://en.wikipedia.org/wiki/Nefazodone "Nefazodone") (Serzone)[\[1\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-Tatsumi1997-1) - [Auvelity](https://en.wikipedia.org/wiki/Dextromethorphan/bupropion "Dextromethorphan/bupropion") (Dextromethorphan/bupropion) ## Serotonin modulators and stimulators (SMSs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=7 "Edit section: Serotonin modulators and stimulators (SMSs)")\] [Serotonin modulators and stimulators](https://en.wikipedia.org/wiki/Serotonin_modulators_and_stimulators "Serotonin modulators and stimulators") include: - [Vilazodone](https://en.wikipedia.org/wiki/Vilazodone "Vilazodone") (Viibryd) - [Vortioxetine](https://en.wikipedia.org/wiki/Vortioxetine "Vortioxetine") (Trintellix, Brintellix) ## Serotonin antagonist and reuptake inhibitors (SARIs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=8 "Edit section: Serotonin antagonist and reuptake inhibitors (SARIs)")\] [Serotonin antagonist and reuptake inhibitors](https://en.wikipedia.org/wiki/Serotonin_antagonist_and_reuptake_inhibitor "Serotonin antagonist and reuptake inhibitor") include: - [Nefazodone](https://en.wikipedia.org/wiki/Nefazodone "Nefazodone") (Dutonin, Nefadar, Serzone) – withdrawn/discontinued in most countries - [Trazodone](https://en.wikipedia.org/wiki/Trazodone "Trazodone") (Desyrel) ### Discontinued/withdrawn \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=9 "Edit section: Discontinued/withdrawn")\] - [Etoperidone](https://en.wikipedia.org/wiki/Etoperidone "Etoperidone") (Axiomin, Etonin) ## Norepinephrine reuptake inhibitors (NRIs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=10 "Edit section: Norepinephrine reuptake inhibitors (NRIs)")\] [Norepinephrine reuptake inhibitors](https://en.wikipedia.org/wiki/Norepinephrine_reuptake_inhibitor "Norepinephrine reuptake inhibitor") include: - [Reboxetine](https://en.wikipedia.org/wiki/Reboxetine "Reboxetine") (Edronax) - [Teniloxazine](https://en.wikipedia.org/wiki/Teniloxazine "Teniloxazine") (Lucelan, Metatone) – also a [5-HT2A receptor](https://en.wikipedia.org/wiki/5-HT2A_receptor "5-HT2A receptor") antagonist - [Viloxazine](https://en.wikipedia.org/wiki/Viloxazine "Viloxazine") (Qelbree, formerly Vivalan) – also a [5-HT2B receptor](https://en.wikipedia.org/wiki/5-HT2B_receptor "5-HT2B receptor") antagonist and [5-HT2C receptor](https://en.wikipedia.org/wiki/5-HT2C_receptor "5-HT2C receptor") [agonist](https://en.wikipedia.org/wiki/Agonist "Agonist") ### Off-label only \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=11 "Edit section: Off-label only")\] - [Atomoxetine](https://en.wikipedia.org/wiki/Atomoxetine "Atomoxetine") (Strattera)[\[2\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid29630286-2)[\[3\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid21155988-3)[\[4\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid19752841-4)[\[5\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid25295426-5) ## Norepinephrine–dopamine reuptake inhibitors (NDRIs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=12 "Edit section: Norepinephrine–dopamine reuptake inhibitors (NDRIs)")\] [Norepinephrine–dopamine reuptake inhibitors](https://en.wikipedia.org/wiki/Norepinephrine%E2%80%93dopamine_reuptake_inhibitor "Norepinephrine–dopamine reuptake inhibitor") include: - [Bupropion](https://en.wikipedia.org/wiki/Bupropion "Bupropion") (Wellbutrin, Elontril) – also a [non-competitive antagonist](https://en.wikipedia.org/wiki/Non-competitive_antagonist "Non-competitive antagonist") of [nicotinic acetylcholine receptors](https://en.wikipedia.org/wiki/Nicotinic_acetylcholine_receptor "Nicotinic acetylcholine receptor")[\[6\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid19897080-6) ### Off-label only \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=13 "Edit section: Off-label only")\] - [Amphetamines](https://en.wikipedia.org/wiki/Amphetamine "Amphetamine") ([Adderall](https://en.wikipedia.org/wiki/Adderall "Adderall"), [Vyvanse](https://en.wikipedia.org/wiki/Vyvanse "Vyvanse")) – actually [norepinephrine–dopamine releasing agents](https://en.wikipedia.org/wiki/Norepinephrine%E2%80%93dopamine_releasing_agent "Norepinephrine–dopamine releasing agent") (NDRAs)[\[7\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid25813654-7)[\[5\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid25295426-5) - [Methylphenidate](https://en.wikipedia.org/wiki/Methylphenidate "Methylphenidate") (Ritalin, Concerta)[\[8\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid10907387-8)[\[9\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid22144657-9) ### Discontinued/withdrawn \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=14 "Edit section: Discontinued/withdrawn")\] - [Amineptine](https://en.wikipedia.org/wiki/Amineptine "Amineptine") (Survector, Maneon) - [Nomifensine](https://en.wikipedia.org/wiki/Nomifensine "Nomifensine") (Merital, Alival) ## Tricyclic antidepressants (TCAs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=15 "Edit section: Tricyclic antidepressants (TCAs)")\] [Tricyclic antidepressants](https://en.wikipedia.org/wiki/Tricyclic_antidepressants "Tricyclic antidepressants") include: - [Amitriptyline](https://en.wikipedia.org/wiki/Amitriptyline "Amitriptyline") (Elavil, Endep) - [Amitriptylinoxide](https://en.wikipedia.org/wiki/Amitriptylinoxide "Amitriptylinoxide") (Amioxid, Ambivalon, Equilibrin) - [Amoxapine](https://en.wikipedia.org/wiki/Amoxapine "Amoxapine") (Asendin) - [Clomipramine](https://en.wikipedia.org/wiki/Clomipramine "Clomipramine") (Anafranil) - [Desipramine](https://en.wikipedia.org/wiki/Desipramine "Desipramine") (Norpramin, Pertofrane) - [Dibenzepin](https://en.wikipedia.org/wiki/Dibenzepin "Dibenzepin") (Noveril, Victoril) - [Dimetacrine](https://en.wikipedia.org/wiki/Dimetacrine "Dimetacrine") (Istonil) - [Dosulepin](https://en.wikipedia.org/wiki/Dosulepin "Dosulepin") (Prothiaden) - [Doxepin](https://en.wikipedia.org/wiki/Doxepin "Doxepin") (Adapin, Sinequan) - [Imipramine](https://en.wikipedia.org/wiki/Imipramine "Imipramine") (Tofranil) - [Lofepramine](https://en.wikipedia.org/wiki/Lofepramine "Lofepramine") (Lomont, Gamanil) - [Melitracen](https://en.wikipedia.org/wiki/Melitracen "Melitracen") (Dixeran, Melixeran, Trausabun) - [Nitroxazepine](https://en.wikipedia.org/wiki/Nitroxazepine "Nitroxazepine") (Sintamil) - [Nortriptyline](https://en.wikipedia.org/wiki/Nortriptyline "Nortriptyline") (Pamelor, Aventyl) - [Noxiptiline](https://en.wikipedia.org/wiki/Noxiptiline "Noxiptiline") (Agedal, Elronon, Nogedal) - [Pipofezine](https://en.wikipedia.org/wiki/Pipofezine "Pipofezine") (Azafen/Azaphen) - [Protriptyline](https://en.wikipedia.org/wiki/Protriptyline "Protriptyline") (Vivactil) - [Trimipramine](https://en.wikipedia.org/wiki/Trimipramine "Trimipramine") (Surmontil) [Opipramol](https://en.wikipedia.org/wiki/Opipramol "Opipramol") (Insidon), [tianeptine](https://en.wikipedia.org/wiki/Tianeptine "Tianeptine") (Stablon, Coaxil) and [amineptine](https://en.wikipedia.org/wiki/Amineptine "Amineptine") (discontinued; formerly Survector, Maneon) are chemically TCAs but are [pharmacodynamically](https://en.wikipedia.org/wiki/Pharmacodynamics "Pharmacodynamics") atypical, and are therefore grouped elsewhere. ### Discontinued/withdrawn \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=16 "Edit section: Discontinued/withdrawn")\] - [Butriptyline](https://en.wikipedia.org/wiki/Butriptyline "Butriptyline") (Evadyne) - [Demexiptiline](https://en.wikipedia.org/wiki/Demexiptiline "Demexiptiline") (Deparon, Tinoran) - [Fluacizine](https://en.wikipedia.org/wiki/Fluacizine "Fluacizine") (Phtorazisin) - [Imipraminoxide](https://en.wikipedia.org/wiki/Imipraminoxide "Imipraminoxide") (Imiprex, Elepsin) - [Iprindole](https://en.wikipedia.org/wiki/Iprindole "Iprindole") (Prondol, Galatur, Tetran) - [Metapramine](https://en.wikipedia.org/wiki/Metapramine "Metapramine") (Timaxel) - [Propizepine](https://en.wikipedia.org/wiki/Propizepine "Propizepine") (Depressin, Vagran) - [Quinupramine](https://en.wikipedia.org/wiki/Quinupramine "Quinupramine") (Kinupril, Kevopril) - [Tiazesim](https://en.wikipedia.org/wiki/Tiazesim "Tiazesim") (Altinil) – actually not a TCA but a [tricyclic-like antidepressant](https://en.wikipedia.org/wiki/Heterocyclic_antidepressant "Heterocyclic antidepressant") - [Tofenacin](https://en.wikipedia.org/wiki/Tofenacin "Tofenacin") (Elamol, Tofacine) – actually not a TCA but a [tricyclic-like antidepressant](https://en.wikipedia.org/wiki/Heterocyclic_antidepressant "Heterocyclic antidepressant") ## Tetracyclic antidepressants (TeCAs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=17 "Edit section: Tetracyclic antidepressants (TeCAs)")\] [Tetracyclic antidepressants](https://en.wikipedia.org/wiki/Tetracyclic_antidepressants "Tetracyclic antidepressants") include: - [Maprotiline](https://en.wikipedia.org/wiki/Maprotiline "Maprotiline") (Ludiomil) - [Mianserin](https://en.wikipedia.org/wiki/Mianserin "Mianserin") (Tolvon) - [Mirtazapine](https://en.wikipedia.org/wiki/Mirtazapine "Mirtazapine") (Remeron) - [Setiptiline](https://en.wikipedia.org/wiki/Setiptiline "Setiptiline") (Tecipul) Mianserin, mirtazapine, and setiptiline are also sometimes described as [noradrenergic and specific serotonergic antidepressants](https://en.wikipedia.org/wiki/Noradrenergic_and_specific_serotonergic_antidepressant "Noradrenergic and specific serotonergic antidepressant") (NaSSAs). ## Monoamine oxidase inhibitors (MAOIs) \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=18 "Edit section: Monoamine oxidase inhibitors (MAOIs)")\] [Monoamine oxidase inhibitors](https://en.wikipedia.org/wiki/Monoamine_oxidase_inhibitor "Monoamine oxidase inhibitor") include ### Irreversible \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=19 "Edit section: Irreversible")\] #### Non-selective \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=20 "Edit section: Non-selective")\] - [Isocarboxazid](https://en.wikipedia.org/wiki/Isocarboxazid "Isocarboxazid") (Marplan) - [Phenelzine](https://en.wikipedia.org/wiki/Phenelzine "Phenelzine") (Nardil) - [Tranylcypromine](https://en.wikipedia.org/wiki/Tranylcypromine "Tranylcypromine") (Parnate) Discontinued/withdrawn - [Benmoxin](https://en.wikipedia.org/wiki/Benmoxin "Benmoxin") (Neuralex) - [Iproclozide](https://en.wikipedia.org/wiki/Iproclozide "Iproclozide") (Sursum) - [Iproniazid](https://en.wikipedia.org/wiki/Iproniazid "Iproniazid") (Marsilid) - [Mebanazine](https://en.wikipedia.org/wiki/Mebanazine "Mebanazine") (Actomol) - [Nialamide](https://en.wikipedia.org/wiki/Nialamide "Nialamide") (Niamid) - [Octamoxin](https://en.wikipedia.org/wiki/Octamoxin "Octamoxin") (Ximaol) - [Pheniprazine](https://en.wikipedia.org/wiki/Pheniprazine "Pheniprazine") (Catron) - [Phenoxypropazine](https://en.wikipedia.org/wiki/Phenoxypropazine "Phenoxypropazine") (Drazine) - [Pivhydrazine](https://en.wikipedia.org/wiki/Pivhydrazine "Pivhydrazine") (Tersavid) - [Safrazine](https://en.wikipedia.org/wiki/Safrazine "Safrazine") (Safra) #### Selective for MAO-B \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=21 "Edit section: Selective for MAO-B")\] - [Selegiline](https://en.wikipedia.org/wiki/Selegiline "Selegiline") (Eldepryl, Zelapar, Emsam) – also a [catecholaminergic activity enhancer](https://en.wikipedia.org/wiki/Monoamine_activity_enhancer "Monoamine activity enhancer") and weak [norepinephrine releasing agent](https://en.wikipedia.org/wiki/Norepinephrine_releasing_agent "Norepinephrine releasing agent") (via [metabolites](https://en.wikipedia.org/wiki/Metabolite "Metabolite")) ### Reversible \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=22 "Edit section: Reversible")\] #### Non-selective \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=23 "Edit section: Non-selective")\] Discontinued/withdrawn - [Caroxazone](https://en.wikipedia.org/wiki/Caroxazone "Caroxazone") (Surodil, Timostenil) #### Selective for MAO-A \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=24 "Edit section: Selective for MAO-A")\] - [Metralindole](https://en.wikipedia.org/wiki/Metralindole "Metralindole") (Inkazan) - [Moclobemide](https://en.wikipedia.org/wiki/Moclobemide "Moclobemide") (Aurorix, Manerix) - [Pirlindole](https://en.wikipedia.org/wiki/Pirlindole "Pirlindole") (Pirazidol) These drugs are sometimes described as [reversible inhibitors of MAO-A](https://en.wikipedia.org/wiki/Reversible_inhibitor_of_MAO-A "Reversible inhibitor of MAO-A") (RIMAs). Discontinued/withdrawn - [Eprobemide](https://en.wikipedia.org/wiki/Eprobemide "Eprobemide") (Befol) - [Minaprine](https://en.wikipedia.org/wiki/Minaprine "Minaprine") (Brantur, Cantor) - [Toloxatone](https://en.wikipedia.org/wiki/Toloxatone "Toloxatone") (Humoryl) ### Mixed \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=25 "Edit section: Mixed")\] #### Non-selective \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=26 "Edit section: Non-selective")\] - [Bifemelane](https://en.wikipedia.org/wiki/Bifemelane "Bifemelane") (Alnert, Celeport) – RIMA, irreversible inhibitor of MAO-B, and weak NRI ## Atypical antipsychotics \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=27 "Edit section: Atypical antipsychotics")\] [Atypical antipsychotics](https://en.wikipedia.org/wiki/Atypical_antipsychotic "Atypical antipsychotic") include: - [Amisulpride](https://en.wikipedia.org/wiki/Amisulpride "Amisulpride") (Solian) – approved in low doses as a monotherapy for [persistent depression](https://en.wikipedia.org/wiki/Dysthymia "Dysthymia") and major depressive disorder[\[10\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-AdisInsight-Amisulpride-10) - [Levosulpiride](https://en.wikipedia.org/wiki/Levosulpiride "Levosulpiride") – approved in low doses for major depressive disorder[\[11\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-AdisInsight-Levosulpiride-11) - [Lumateperone](https://en.wikipedia.org/wiki/Lumateperone "Lumateperone") (Caplyta) – approved as a monotherapy for [bipolar depression](https://en.wikipedia.org/wiki/Bipolar_depression "Bipolar depression") - [Lurasidone](https://en.wikipedia.org/wiki/Lurasidone "Lurasidone") (Latuda) – approved as a monotherapy for bipolar depression - [Quetiapine](https://en.wikipedia.org/wiki/Quetiapine "Quetiapine") (Seroquel) – approved as a monotherapy for bipolar depression - [Sulpiride](https://en.wikipedia.org/wiki/Sulpiride "Sulpiride") – approved in low doses as a monotherapy for major depressive disorder[\[12\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-Sulpiride-Japanese-Label-12) ## Others \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=28 "Edit section: Others")\] ### Marketed \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=29 "Edit section: Marketed")\] - [D-Phenylalanine](https://en.wikipedia.org/wiki/D-Phenylalanine "D-Phenylalanine") (DPA, D \-Phe; Deprenon, Sabiben, Sabiden) – [enkephalinase inhibitor](https://en.wikipedia.org/wiki/Enkephalinase_inhibitor "Enkephalinase inhibitor") - [Agomelatine](https://en.wikipedia.org/wiki/Agomelatine "Agomelatine") (Valdoxan) – [5-HT2C receptor](https://en.wikipedia.org/wiki/5-HT2C_receptor "5-HT2C receptor") [antagonist](https://en.wikipedia.org/wiki/Receptor_antagonist "Receptor antagonist") and [MT1](https://en.wikipedia.org/wiki/Melatonin_receptor_1A "Melatonin receptor 1A") and [MT2 receptor](https://en.wikipedia.org/wiki/Melatonin_receptor_1B "Melatonin receptor 1B") agonist - [Auvelity](https://en.wikipedia.org/wiki/Dextromethorphan/bupropion "Dextromethorphan/bupropion") (Dextromethorphan/bupropion) - [Brexanolone](https://en.wikipedia.org/wiki/Brexanolone "Brexanolone") (allopregnanolone; Zulresso) – [GABAA receptor positive allosteric modulator](https://en.wikipedia.org/wiki/GABAA_receptor "GABAA receptor") – approved for [postpartum depression](https://en.wikipedia.org/wiki/Postpartum_depression "Postpartum depression") - [Esketamine](https://en.wikipedia.org/wiki/Esketamine "Esketamine") (Spravato) – non-competitive NMDA receptor antagonist, other actions[\[13\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-SpravatoLabel-13) - [Gepirone](https://en.wikipedia.org/wiki/Gepirone "Gepirone") (Exxua) – [5-HT1A receptor](https://en.wikipedia.org/wiki/5-HT1A_receptor "5-HT1A receptor") [partial agonist](https://en.wikipedia.org/wiki/Partial_agonist "Partial agonist") and [α2\-adrenergic receptor](https://en.wikipedia.org/wiki/Alpha-2_adrenergic_receptor "Alpha-2 adrenergic receptor") antagonist - [Opipramol](https://en.wikipedia.org/wiki/Opipramol "Opipramol") (Insidon) — [σ1 receptor](https://en.wikipedia.org/wiki/Sigma-1_receptor "Sigma-1 receptor") agonist, other actions - [Tianeptine](https://en.wikipedia.org/wiki/Tianeptine "Tianeptine") (Stablon, Coaxil, Tianeurax) – weak and atypical [μ-opioid receptor](https://en.wikipedia.org/wiki/%CE%9C-opioid_receptor "Μ-opioid receptor") agonist, other actions ### Off-label only \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=30 "Edit section: Off-label only")\] - [Ketamine](https://en.wikipedia.org/wiki/Ketamine "Ketamine") (Ketalar) – non-competitive [NMDA receptor antagonist](https://en.wikipedia.org/wiki/NMDA_receptor_antagonist "NMDA receptor antagonist")[\[14\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid26768892-14) ### Discontinued/withdrawn \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=31 "Edit section: Discontinued/withdrawn")\] - [α-Methyltryptamine](https://en.wikipedia.org/wiki/%CE%91-Methyltryptamine "Α-Methyltryptamine") \[αMT\] (Indopan) – non-selective [serotonin receptor agonist](https://en.wikipedia.org/wiki/Serotonin_receptor_agonist "Serotonin receptor agonist"), [serotonin–norepinephrine–dopamine releasing agent](https://en.wikipedia.org/wiki/Serotonin%E2%80%93norepinephrine%E2%80%93dopamine_releasing_agent "Serotonin–norepinephrine–dopamine releasing agent") (SNDRA), and weak RIMA - [Etryptamine](https://en.wikipedia.org/wiki/Etryptamine "Etryptamine") \[α-Ethyltryptamine (αET)\] (Monase) – non-selective serotonin receptor agonist, SNDRA, and weak RIMA - [Indeloxazine](https://en.wikipedia.org/wiki/Indeloxazine "Indeloxazine") (Elen, Noin) – [serotonin releasing agent](https://en.wikipedia.org/wiki/Serotonin_releasing_agent "Serotonin releasing agent") (SRA), NRI, and NMDA receptor antagonist - [Oxaflozane](https://en.wikipedia.org/wiki/Oxaflozane "Oxaflozane") (Conflictan) – 5-HT1A, 5-HT2A, and 5-HT2C receptor agonist - [Pivagabine](https://en.wikipedia.org/wiki/Pivagabine "Pivagabine") (Tonerg) – unknown/unclear [mechanism of action](https://en.wikipedia.org/wiki/Mechanism_of_action "Mechanism of action") ### Over-the-counter \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=32 "Edit section: Over-the-counter")\] The following antidepressants are available both with a [prescription](https://en.wikipedia.org/wiki/Medical_prescription "Medical prescription") and [over-the-counter](https://en.wikipedia.org/wiki/Over-the-counter "Over-the-counter"): - [Ademetionine](https://en.wikipedia.org/wiki/Ademetionine "Ademetionine") \[S\-Adenosyl- L \-methionine (SAMe)\] (Heptral, Transmetil, Samyl) – [cofactor](https://en.wikipedia.org/wiki/Cofactor_\(biochemistry\) "Cofactor (biochemistry)") in [monoamine neurotransmitter](https://en.wikipedia.org/wiki/Monoamine_neurotransmitter "Monoamine neurotransmitter") [biosynthesis](https://en.wikipedia.org/wiki/Biosynthesis "Biosynthesis") - [Hypericum perforatum](https://en.wikipedia.org/wiki/Hypericum_perforatum "Hypericum perforatum") \[St. John's Wort (SJW)\] (Jarsin, Kira, Movina) – [TRPC6](https://en.wikipedia.org/wiki/TRPC6 "TRPC6") activator, and various other actions - [Oxitriptan](https://en.wikipedia.org/wiki/Oxitriptan "Oxitriptan") \[5-Hydroxytryptophan (5-HTP)\] (Cincofarm, Levothym, Triptum) – [precursor](https://en.wikipedia.org/wiki/Precursor_\(biochemistry\) "Precursor (biochemistry)") in [serotonin](https://en.wikipedia.org/wiki/Serotonin "Serotonin") biosynthesis - [Tryptophan](https://en.wikipedia.org/wiki/Tryptophan "Tryptophan") (Tryptan, Optimax, Aminomine) – precursor in serotonin biosynthesis ## Adjunctive treatments \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=33 "Edit section: Adjunctive treatments")\] ### Atypical antipsychotics \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=34 "Edit section: Atypical antipsychotics")\] [Atypical antipsychotics](https://en.wikipedia.org/wiki/Atypical_antipsychotic "Atypical antipsychotic") include: - [Aripiprazole](https://en.wikipedia.org/wiki/Aripiprazole "Aripiprazole") (Abilify) – approved as an adjunct to antidepressant for major depression - [Brexpiprazole](https://en.wikipedia.org/wiki/Brexpiprazole "Brexpiprazole") (Rexulti) – approved as an adjunct to antidepressant for major depression - [Lumateperone](https://en.wikipedia.org/wiki/Lumateperone "Lumateperone") (Caplyta) – approved as an adjunct to mood stabilizer for bipolar depression - [Lurasidone](https://en.wikipedia.org/wiki/Lurasidone "Lurasidone") (Latuda) – approved as an adjunct to mood stabilizer for bipolar depression - [Olanzapine](https://en.wikipedia.org/wiki/Olanzapine "Olanzapine") (Zyprexa) – approved as an adjunct to antidepressant for major depression - [Quetiapine](https://en.wikipedia.org/wiki/Quetiapine "Quetiapine") (Seroquel) – approved as an adjunct to antidepressant or mood stabilizer for major depression and bipolar depression #### Off-label only \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=35 "Edit section: Off-label only")\] - [Risperidone](https://en.wikipedia.org/wiki/Risperidone "Risperidone") (Risperdal) ### Typical antipsychotics \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=36 "Edit section: Typical antipsychotics")\] [Typical antipsychotics](https://en.wikipedia.org/wiki/Typical_antipsychotics "Typical antipsychotics") include: None currently approved #### Off-label only \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=37 "Edit section: Off-label only")\] - [Trifluoperazine](https://en.wikipedia.org/wiki/Trifluoperazine "Trifluoperazine") (Stelazine)[\[15\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid27514300-15) ### Dopamine reuptake inhibitor \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=38 "Edit section: Dopamine reuptake inhibitor")\] [Dopamine reuptake inhibitors](https://en.wikipedia.org/wiki/Dopamine_reuptake_inhibitor "Dopamine reuptake inhibitor") include: None currently approved #### Off-label only \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=39 "Edit section: Off-label only")\] - [Modafinil](https://en.wikipedia.org/wiki/Modafinil "Modafinil") (Provigil)[\[16\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid32447354-16)[\[17\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid28318897-17)[\[18\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid31643130-18)[\[19\]](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_note-pmid28256707-19) - [Armodafinil](https://en.wikipedia.org/wiki/Armodafinil "Armodafinil") (Nuvigil) ### Others \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=40 "Edit section: Others")\] #### Off-label only \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=41 "Edit section: Off-label only")\] - [Buspirone](https://en.wikipedia.org/wiki/Buspirone "Buspirone") (Buspar) – 5-HT1A receptor partial agonist - [Lithium](https://en.wikipedia.org/wiki/Lithium_\(medication\) "Lithium (medication)") (Eskalith, Lithobid) – [mood stabilizer](https://en.wikipedia.org/wiki/Mood_stabilizer "Mood stabilizer") (mechanism of action unknown/unclear) - [Thyroxine](https://en.wikipedia.org/wiki/Thyroxine "Thyroxine") (T4) – [thyroid hormone](https://en.wikipedia.org/wiki/Thyroid_hormone "Thyroid hormone") ([thyroid hormone receptor](https://en.wikipedia.org/wiki/Thyroid_hormone_receptor "Thyroid hormone receptor") agonist) - [Triiodothyronine](https://en.wikipedia.org/wiki/Triiodothyronine "Triiodothyronine") (T3) – thyroid hormone (thyroid hormone receptor agonist) ## Combination products \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=42 "Edit section: Combination products")\] - [Amitriptyline/chlordiazepoxide](https://en.wikipedia.org/wiki/Amitriptyline/chlordiazepoxide "Amitriptyline/chlordiazepoxide") (Limbitrol) – TCA and [benzodiazepine](https://en.wikipedia.org/wiki/Benzodiazepine "Benzodiazepine") combination - [Amitriptyline/perphenazine](https://en.wikipedia.org/wiki/Amitriptyline/perphenazine "Amitriptyline/perphenazine") (Etafron) – TCA and typical antipsychotic combination - [Bupropion/dextromethorphan](https://en.wikipedia.org/wiki/Bupropion/dextromethorphan "Bupropion/dextromethorphan") (Auvelity) – [non-competitive](https://en.wikipedia.org/wiki/Non-competitive_antagonist "Non-competitive antagonist") NMDA receptor antagonist, [σ1 receptor](https://en.wikipedia.org/wiki/Sigma-1_receptor "Sigma-1 receptor") agonist, SNRI, NDRI, other actions - [Flupentixol/melitracen](https://en.wikipedia.org/wiki/Flupentixol/melitracen "Flupentixol/melitracen") (Deanxit) – TCA and typical antipsychotic combination - [Olanzapine/fluoxetine](https://en.wikipedia.org/wiki/Olanzapine/fluoxetine "Olanzapine/fluoxetine") (Symbyax) – SSRI and atypical antipsychotic combination – approved as a monotherapy for bipolar depression and treatment-resistant depression - [Tranylcypromine/trifluoperazine](https://en.wikipedia.org/wiki/Tranylcypromine/trifluoperazine "Tranylcypromine/trifluoperazine") (Parstelin, Parmodalin, Jatrosom N, Stelapar) – MAOI and typical antipsychotic combination ## See also \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=43 "Edit section: See also")\] - [List of investigational antidepressants](https://en.wikipedia.org/wiki/List_of_investigational_antidepressants "List of investigational antidepressants") ## References \[[edit](https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&action=edit&section=44 "Edit section: References")\] 1. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-Tatsumi1997_1-0) Tatsumi M, Groshan K, Blakely RD, Richelson E (December 1997). "Pharmacological profile of antidepressants and related compounds at human monoamine transporters". European Journal of Pharmacology. 340 (2–3\): 249–258\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1016/s0014-2999(97)01393-9](https://doi.org/10.1016%2Fs0014-2999%2897%2901393-9). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [9537821](https://pubmed.ncbi.nlm.nih.gov/9537821). 2. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid29630286_2-0) Fedder D, Patel H, Saadabadi A (March 2023). ["Atomoxetine"](https://www.ncbi.nlm.nih.gov/books/NBK493234/). StatPearls \[Internet\]. Treasure Island (FL): StatPearls Publishing. [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [29630286](https://pubmed.ncbi.nlm.nih.gov/29630286). 3. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid21155988_3-0) Dell'Osso B, Palazzo MC, Oldani L, Altamura AC (December 2011). ["The noradrenergic action in antidepressant treatments: pharmacological and clinical aspects"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493872). CNS Neurosci Ther. 17 (6): 723–32\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1111/j.1755-5949.2010.00217.x](https://doi.org/10.1111%2Fj.1755-5949.2010.00217.x). [PMC](https://en.wikipedia.org/wiki/PMC_\(identifier\) "PMC (identifier)") [6493872](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493872). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [21155988](https://pubmed.ncbi.nlm.nih.gov/21155988). 4. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid19752841_4-0) Fleurence R, Williamson R, Jing Y, Kim E, Tran QV, Pikalov AS, et al. (2009). "A systematic review of augmentation strategies for patients with major depressive disorder". Psychopharmacol Bull. 42 (3): 57–90\. [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [19752841](https://pubmed.ncbi.nlm.nih.gov/19752841). 5. ^ [*a](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid25295426_5-0) [b](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid25295426_5-1) Corp SA, Gitlin MJ, Altshuler LL (September 2014). "A review of the use of stimulants and stimulant alternatives in treating bipolar depression and major depressive disorder". J Clin Psychiatry. 75* (9): 1010–8\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.4088/JCP.13r08851](https://doi.org/10.4088%2FJCP.13r08851). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [25295426](https://pubmed.ncbi.nlm.nih.gov/25295426). 6. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid19897080_6-0) Arias HR, Santamaría A, Ali SF (2009). "Pharmacological and neurotoxicological actions mediated by bupropion and diethylpropion". Int. Rev. Neurobiol. International Review of Neurobiology. 88: 223–55\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1016/S0074-7742(09)88009-4](https://doi.org/10.1016%2FS0074-7742%2809%2988009-4). [ISBN](https://en.wikipedia.org/wiki/ISBN_\(identifier\) "ISBN (identifier)") [9780123745040](https://en.wikipedia.org/wiki/Special:BookSources/9780123745040 "Special:BookSources/9780123745040") . [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [19897080](https://pubmed.ncbi.nlm.nih.gov/19897080). 7. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid25813654_7-0) Dale E, Bang-Andersen B, Sánchez C (2015). ["Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs"](https://doi.org/10.1016%2Fj.bcp.2015.03.011). Biochem. Pharmacol. 95 (2): 81–97\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1016/j.bcp.2015.03.011](https://doi.org/10.1016%2Fj.bcp.2015.03.011). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [25813654](https://pubmed.ncbi.nlm.nih.gov/25813654). 8. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid10907387_8-0) Challman TD, Lipsky JJ (2000). ["Methylphenidate: its pharmacology and uses"](https://doi.org/10.4065%2F75.7.711). Mayo Clin. Proc. 75 (7): 711–21\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.4065/75.7.711](https://doi.org/10.4065%2F75.7.711). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [10907387](https://pubmed.ncbi.nlm.nih.gov/10907387). 9. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid22144657_9-0) Prommer E (2012). "Methylphenidate: established and expanding roles in symptom management". Am J Hosp Palliat Care. 29 (6): 483–90\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1177/1049909111427029](https://doi.org/10.1177%2F1049909111427029). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [22144657](https://pubmed.ncbi.nlm.nih.gov/22144657). [S2CID](https://en.wikipedia.org/wiki/S2CID_\(identifier\) "S2CID (identifier)") [21384037](https://api.semanticscholar.org/CorpusID:21384037). 10. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-AdisInsight-Amisulpride_10-0) ["Amisulpride"](https://adisinsight.springer.com/drugs/800005602). AdisInsight. 24 October 2021. Retrieved 22 October 2024. 11. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-AdisInsight-Levosulpiride_11-0) ["Levosulpiride"](https://adisinsight.springer.com/drugs/800003554). AdisInsight. 24 October 2021. Retrieved 22 October 2024. 12. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-Sulpiride-Japanese-Label_12-0) ["Kusuri-no-Shiori(Drug Information Sheet)"](https://www.rad-ar.or.jp/siori/english/search/result?n=35833). くすりの適正使用協議会. Retrieved 22 October 2024. 13. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-SpravatoLabel_13-0) ["SPRAVATO™ (esketamine) nasal spray FDA label"](https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/211243lbl.pdf) (PDF). [Food and Drug Administration](https://en.wikipedia.org/wiki/Food_and_Drug_Administration "Food and Drug Administration"). 5 March 2019. Retrieved 6 March 2019. 14. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid26768892_14-0) Zhang MW, Harris KM, Ho RC (2016). ["Is off-label repeat prescription of ketamine as a rapid antidepressant safe? Controversies, ethical concerns, and legal implications"](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714497). BMC Med Ethics. 17: 4. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1186/s12910-016-0087-3](https://doi.org/10.1186%2Fs12910-016-0087-3). [PMC](https://en.wikipedia.org/wiki/PMC_\(identifier\) "PMC (identifier)") [4714497](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714497). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [26768892](https://pubmed.ncbi.nlm.nih.gov/26768892). 15. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid27514300_15-0) Thase ME (2016). "Adverse Effects of Second-Generation Antipsychotics as Adjuncts to Antidepressants: Are the Risks Worth the Benefits?". Psychiatr. Clin. North Am. 39 (3): 477–86\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1016/j.psc.2016.04.008](https://doi.org/10.1016%2Fj.psc.2016.04.008). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [27514300](https://pubmed.ncbi.nlm.nih.gov/27514300). 16. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid32447354_16-0) Urban AE, Cubała WJ (February 2020). ["The role of eugeroics in the treatment of affective disorders"](https://doi.org/10.12740%2FPP%2FOnlineFirst%2F90687). Psychiatr Pol. 54 (1): 21–33\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.12740/PP/OnlineFirst/90687](https://doi.org/10.12740%2FPP%2FOnlineFirst%2F90687). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [32447354](https://pubmed.ncbi.nlm.nih.gov/32447354). 17. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid28318897_17-0) Kleeblatt J, Betzler F, Kilarski LL, Bschor T, Köhler S (May 2017). "Efficacy of off-label augmentation in unipolar depression: A systematic review of the evidence". Eur Neuropsychopharmacol. 27 (5): 423–441\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1016/j.euroneuro.2017.03.003](https://doi.org/10.1016%2Fj.euroneuro.2017.03.003). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [28318897](https://pubmed.ncbi.nlm.nih.gov/28318897). [S2CID](https://en.wikipedia.org/wiki/S2CID_\(identifier\) "S2CID (identifier)") [3740987](https://api.semanticscholar.org/CorpusID:3740987). 18. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid31643130_18-0) Nunez NA, Singh B, Romo-Nava F, Joseph B, Veldic M, Cuellar-Barboza A, et al. (March 2020). ["Efficacy and tolerability of adjunctive modafinil/armodafinil in bipolar depression: A meta-analysis of randomized controlled trials"](https://doi.org/10.1111%2Fbdi.12859). Bipolar Disord. 22 (2): 109–120\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1111/bdi.12859](https://doi.org/10.1111%2Fbdi.12859). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [31643130](https://pubmed.ncbi.nlm.nih.gov/31643130). 19. [^](https://en.wikipedia.org/wiki/List_of_antidepressants#cite_ref-pmid28256707_19-0) Szmulewicz AG, Angriman F, Samamé C, Ferraris A, Vigo D, Strejilevich SA (June 2017). "Dopaminergic agents in the treatment of bipolar depression: a systematic review and meta-analysis". Acta Psychiatr Scand. 135 (6): 527–538\. [doi](https://en.wikipedia.org/wiki/Doi_\(identifier\) "Doi (identifier)"):[10\.1111/acps.12712](https://doi.org/10.1111%2Facps.12712). [PMID](https://en.wikipedia.org/wiki/PMID_\(identifier\) "PMID (identifier)") [28256707](https://pubmed.ncbi.nlm.nih.gov/28256707). [S2CID](https://en.wikipedia.org/wiki/S2CID_\(identifier\) "S2CID (identifier)") [3712257](https://api.semanticscholar.org/CorpusID:3712257). \| [v](https://en.wikipedia.org/wiki/Template:Antidepressants "Template:Antidepressants") [t](https://en.wikipedia.org/wiki/Template_talk:Antidepressants "Template talk:Antidepressants") [e](https://en.wikipedia.org/wiki/Special:EditPage/Template:Antidepressants "Special:EditPage/Template:Antidepressants")[Antidepressants](https://en.wikipedia.org/wiki/Antidepressant "Antidepressant") ([N06A](https://en.wikipedia.org/wiki/ATC_code_N06#N06A "ATC code N06")) \| \| \|---\|---\| \| Specific [reuptake inhibitors](https://en.wikipedia.org/wiki/Reuptake_inhibitor "Reuptake inhibitor") or [receptor modulators](https://en.wikipedia.org/wiki/Receptor_modulator "Receptor modulator") \| \| \| \| \| \| [SSRIs](https://en.wikipedia.org/wiki/Selective_serotonin_reuptake_inhibitors "Selective serotonin reuptake inhibitors")Tooltip Selective serotonin reuptake inhibitors \| [Citalopram](https://en.wikipedia.org/wiki/Citalopram "Citalopram") [Escitalopram](https://en.wikipedia.org/wiki/Escitalopram "Escitalopram") [Fluoxetine](https://en.wikipedia.org/wiki/Fluoxetine "Fluoxetine")\# [Fluvoxamine](https://en.wikipedia.org/wiki/Fluvoxamine "Fluvoxamine") [Indalpine](https://en.wikipedia.org/wiki/Indalpine "Indalpine")‡ [Paroxetine](https://en.wikipedia.org/wiki/Paroxetine "Paroxetine") [Sertraline](https://en.wikipedia.org/wiki/Sertraline "Sertraline") [Zimelidine](https://en.wikipedia.org/wiki/Zimelidine "Zimelidine")‡ \| \| [SNRIs](https://en.wikipedia.org/wiki/Serotonin%E2%80%93norepinephrine_reuptake_inhibitors "Serotonin–norepinephrine reuptake inhibitors")Tooltip Serotonin–norepinephrine reuptake inhibitors \| [Desvenlafaxine](https://en.wikipedia.org/wiki/Desvenlafaxine "Desvenlafaxine") [Duloxetine](https://en.wikipedia.org/wiki/Duloxetine "Duloxetine") [Levomilnacipran](https://en.wikipedia.org/wiki/Levomilnacipran "Levomilnacipran") [Milnacipran](https://en.wikipedia.org/wiki/Milnacipran "Milnacipran") [Tofenacin](https://en.wikipedia.org/wiki/Tofenacin "Tofenacin") [Venlafaxine](https://en.wikipedia.org/wiki/Venlafaxine "Venlafaxine") \| \| [NRIs](https://en.wikipedia.org/wiki/Norepinephrine_reuptake_inhibitors "Norepinephrine reuptake inhibitors")Tooltip Norepinephrine reuptake inhibitors \| [Atomoxetine](https://en.wikipedia.org/wiki/Atomoxetine "Atomoxetine") [Reboxetine](https://en.wikipedia.org/wiki/Reboxetine "Reboxetine") [Viloxazine](https://en.wikipedia.org/wiki/Viloxazine "Viloxazine") \| \| [NDRIs](https://en.wikipedia.org/wiki/Norepinephrine%E2%80%93dopamine_reuptake_inhibitors "Norepinephrine–dopamine reuptake inhibitors")Tooltip Norepinephrine–dopamine reuptake inhibitors \| [Amineptine](https://en.wikipedia.org/wiki/Amineptine "Amineptine")‡ [Bupropion](https://en.wikipedia.org/wiki/Bupropion "Bupropion") [Nomifensine](https://en.wikipedia.org/wiki/Nomifensine "Nomifensine")‡ \| \| [NaSSAs](https://en.wikipedia.org/wiki/Noradrenergic_and_specific_serotonergic_antidepressants "Noradrenergic and specific serotonergic antidepressants")Tooltip Noradrenergic and specific serotonergic antidepressants \| [Mianserin](https://en.wikipedia.org/wiki/Mianserin "Mianserin") [Mirtazapine](https://en.wikipedia.org/wiki/Mirtazapine "Mirtazapine") [Setiptiline](https://en.wikipedia.org/wiki/Setiptiline "Setiptiline") \| \| [SARIs](https://en.wikipedia.org/wiki/Serotonin_antagonist_and_reuptake_inhibitors "Serotonin antagonist and reuptake inhibitors")Tooltip Serotonin antagonist and reuptake inhibitors \| [Etoperidone](https://en.wikipedia.org/wiki/Etoperidone "Etoperidone") [Nefazodone](https://en.wikipedia.org/wiki/Nefazodone "Nefazodone") [Trazodone](https://en.wikipedia.org/wiki/Trazodone "Trazodone") \| \| [SMS](https://en.wikipedia.org/wiki/Serotonin_modulator_and_stimulators "Serotonin modulator and stimulators")Tooltip Serotonin modulator and stimulators \| [Vilazodone](https://en.wikipedia.org/wiki/Vilazodone "Vilazodone") [Vortioxetine](https://en.wikipedia.org/wiki/Vortioxetine "Vortioxetine") \| \| Others \| [Agomelatine](https://en.wikipedia.org/wiki/Agomelatine "Agomelatine") [Amisulpride](https://en.wikipedia.org/wiki/Amisulpride "Amisulpride") [Dextromethorphan/bupropion](https://en.wikipedia.org/wiki/Dextromethorphan/bupropion "Dextromethorphan/bupropion") [Esketamine](https://en.wikipedia.org/wiki/Esketamine "Esketamine") [Etryptamine](https://en.wikipedia.org/wiki/Alpha-Ethyltryptamine "Alpha-Ethyltryptamine")‡ [Gepirone](https://en.wikipedia.org/wiki/Gepirone "Gepirone") [Indeloxazine](https://en.wikipedia.org/wiki/Indeloxazine "Indeloxazine") [Flupentixol](https://en.wikipedia.org/wiki/Flupentixol "Flupentixol") [Ketamine](https://en.wikipedia.org/wiki/Ketamine "Ketamine")§ [Medifoxamine](https://en.wikipedia.org/wiki/Medifoxamine "Medifoxamine")‡ [Metryptamine](https://en.wikipedia.org/wiki/Alpha-Methyltryptamine "Alpha-Methyltryptamine")‡ [Oxaflozane](https://en.wikipedia.org/wiki/Oxaflozane "Oxaflozane")‡ [Pivagabine](https://en.wikipedia.org/wiki/Pivagabine "Pivagabine")‡ [Tandospirone](https://en.wikipedia.org/wiki/Tandospirone "Tandospirone") [Teniloxazine](https://en.wikipedia.org/wiki/Teniloxazine "Teniloxazine") [Tianeptine](https://en.wikipedia.org/wiki/Tianeptine "Tianeptine") \| \| [Tricyclic](https://en.wikipedia.org/wiki/Tricyclic "Tricyclic") and [tetracyclic antidepressants](https://en.wikipedia.org/wiki/Tetracyclic_antidepressant "Tetracyclic antidepressant") \| \| \| \| \| \| [TCAs](https://en.wikipedia.org/wiki/Tricyclic_antidepressants "Tricyclic antidepressants")Tooltip Tricyclic antidepressants \| [Amineptine](https://en.wikipedia.org/wiki/Amineptine "Amineptine")‡ [Amitriptyline](https://en.wikipedia.org/wiki/Amitriptyline "Amitriptyline")\# [Amitriptylinoxide](https://en.wikipedia.org/wiki/Amitriptylinoxide "Amitriptylinoxide") [Amoxapine](https://en.wikipedia.org/wiki/Amoxapine "Amoxapine") [Butriptyline](https://en.wikipedia.org/wiki/Butriptyline "Butriptyline")‡ [Clomipramine](https://en.wikipedia.org/wiki/Clomipramine "Clomipramine")\# [Demexiptiline](https://en.wikipedia.org/wiki/Demexiptiline "Demexiptiline")‡ [Desipramine](https://en.wikipedia.org/wiki/Desipramine "Desipramine") [Dibenzepin](https://en.wikipedia.org/wiki/Dibenzepin "Dibenzepin") [Dimetacrine](https://en.wikipedia.org/wiki/Dimetacrine "Dimetacrine")‡ [Dosulepin](https://en.wikipedia.org/wiki/Dosulepin "Dosulepin") [Doxepin](https://en.wikipedia.org/wiki/Doxepin "Doxepin") [Imipramine](https://en.wikipedia.org/wiki/Imipramine "Imipramine") [Imipraminoxide](https://en.wikipedia.org/wiki/Imipraminoxide "Imipraminoxide")‡ [Iprindole](https://en.wikipedia.org/wiki/Iprindole "Iprindole")‡ [Lofepramine](https://en.wikipedia.org/wiki/Lofepramine "Lofepramine") [Melitracen](https://en.wikipedia.org/wiki/Melitracen "Melitracen") [Metapramine](https://en.wikipedia.org/wiki/Metapramine "Metapramine")‡ [Nitroxazepine](https://en.wikipedia.org/wiki/Nitroxazepine "Nitroxazepine") [Nortriptyline](https://en.wikipedia.org/wiki/Nortriptyline "Nortriptyline") [Noxiptiline](https://en.wikipedia.org/wiki/Noxiptiline "Noxiptiline") [Opipramol](https://en.wikipedia.org/wiki/Opipramol "Opipramol") [Pipofezine](https://en.wikipedia.org/wiki/Pipofezine "Pipofezine") [Propizepine](https://en.wikipedia.org/wiki/Propizepine "Propizepine")‡ [Protriptyline](https://en.wikipedia.org/wiki/Protriptyline "Protriptyline") [Quinupramine](https://en.wikipedia.org/wiki/Quinupramine "Quinupramine")‡ [Tianeptine](https://en.wikipedia.org/wiki/Tianeptine "Tianeptine") [Trimipramine](https://en.wikipedia.org/wiki/Trimipramine "Trimipramine") \| \| [TeCAs](https://en.wikipedia.org/wiki/Tetracyclic_antidepressants "Tetracyclic antidepressants")Tooltip Tetracyclic antidepressants \| [Maprotiline](https://en.wikipedia.org/wiki/Maprotiline "Maprotiline") [Mianserin](https://en.wikipedia.org/wiki/Mianserin "Mianserin") [Mirtazapine](https://en.wikipedia.org/wiki/Mirtazapine "Mirtazapine") [Setiptiline](https://en.wikipedia.org/wiki/Setiptiline "Setiptiline") \| \| Others \| [Tiazesim](https://en.wikipedia.org/wiki/Tiazesim "Tiazesim") \| \| [Monoamine oxidase inhibitors](https://en.wikipedia.org/wiki/Monoamine_oxidase_inhibitor "Monoamine oxidase inhibitor") \| \| \| \| \| \| Non-selective \| Irreversible: [Benmoxin](https://en.wikipedia.org/wiki/Benmoxin "Benmoxin")‡ [Iproclozide](https://en.wikipedia.org/wiki/Iproclozide "Iproclozide")‡ [Iproniazid](https://en.wikipedia.org/wiki/Iproniazid "Iproniazid")‡ [Isocarboxazid](https://en.wikipedia.org/wiki/Isocarboxazid "Isocarboxazid") [Isoniazid](https://en.wikipedia.org/wiki/Isoniazid "Isoniazid")\# [Linezolid](https://en.wikipedia.org/wiki/Linezolid "Linezolid")\# [Mebanazine](https://en.wikipedia.org/wiki/Mebanazine "Mebanazine")‡ [Nialamide](https://en.wikipedia.org/wiki/Nialamide "Nialamide")‡ [Octamoxin](https://en.wikipedia.org/wiki/Octamoxin "Octamoxin")‡ [Phenelzine](https://en.wikipedia.org/wiki/Phenelzine "Phenelzine") [Pheniprazine](https://en.wikipedia.org/wiki/Pheniprazine "Pheniprazine")‡ [Phenoxypropazine](https://en.wikipedia.org/wiki/Phenoxypropazine "Phenoxypropazine")‡ [Pivhydrazine](https://en.wikipedia.org/wiki/Pivhydrazine "Pivhydrazine")‡ [Safrazine](https://en.wikipedia.org/wiki/Safrazine "Safrazine")‡ [Tedizolid](https://en.wikipedia.org/wiki/Tedizolid "Tedizolid") [Tranylcypromine](https://en.wikipedia.org/wiki/Tranylcypromine "Tranylcypromine") Reversible: [Caroxazone](https://en.wikipedia.org/wiki/Caroxazone "Caroxazone")‡ Mixed: [Bifemelane](https://en.wikipedia.org/wiki/Bifemelane "Bifemelane") \| \| [MAOA](https://en.wikipedia.org/wiki/Monoamine_oxidase_A "Monoamine oxidase A")Tooltip Monoamine oxidase A\-selective \| Reversible: [Eprobemide](https://en.wikipedia.org/wiki/Eprobemide "Eprobemide") [Metralindole](https://en.wikipedia.org/wiki/Metralindole "Metralindole") [Minaprine](https://en.wikipedia.org/wiki/Minaprine "Minaprine")‡ [Moclobemide](https://en.wikipedia.org/wiki/Moclobemide "Moclobemide") [Pirlindole](https://en.wikipedia.org/wiki/Pirlindole "Pirlindole") [Tetrindole](https://en.wikipedia.org/wiki/Tetrindole "Tetrindole") [Toloxatone](https://en.wikipedia.org/wiki/Toloxatone "Toloxatone") \| \| [MAOB](https://en.wikipedia.org/wiki/Monoamine_oxidase_B "Monoamine oxidase B")Tooltip Monoamine oxidase B\-selective \| Irreversible: [Selegiline](https://en.wikipedia.org/wiki/Selegiline "Selegiline") \| \| [Adjunctive therapies](https://en.wikipedia.org/wiki/Adjuvant_therapy "Adjuvant therapy") \| \| \| [Atypical antipsychotics](https://en.wikipedia.org/wiki/Atypical_antipsychotic "Atypical antipsychotic") ([aripiprazole](https://en.wikipedia.org/wiki/Aripiprazole "Aripiprazole"), [brexpiprazole](https://en.wikipedia.org/wiki/Brexpiprazole "Brexpiprazole"), [lurasidone](https://en.wikipedia.org/wiki/Lurasidone "Lurasidone"), [olanzapine](https://en.wikipedia.org/wiki/Olanzapine "Olanzapine"), [quetiapine](https://en.wikipedia.org/wiki/Quetiapine "Quetiapine"), [risperidone](https://en.wikipedia.org/wiki/Risperidone "Risperidone")) [Buspirone](https://en.wikipedia.org/wiki/Buspirone "Buspirone") [Lithium](https://en.wikipedia.org/wiki/Lithium_\(medication\) "Lithium (medication)") ([lithium carbonate](https://en.wikipedia.org/wiki/Lithium_carbonate "Lithium carbonate"), [lithium citrate](https://en.wikipedia.org/wiki/Lithium_citrate "Lithium citrate")) [Thyroid hormones](https://en.wikipedia.org/wiki/Thyroid_hormone "Thyroid hormone") ([triiodothyronine](https://en.wikipedia.org/wiki/Triiodothyronine "Triiodothyronine") (T3), [levothyroxine](https://en.wikipedia.org/wiki/Levothyroxine "Levothyroxine") (T4)) \| \| \| Miscellaneous \| \| \| [Ademetionine (SAMe)](https://en.wikipedia.org/wiki/Ademetionine "Ademetionine") [GABAkine](https://en.wikipedia.org/wiki/GABAA_receptor_positive_allosteric_modulator "GABAA receptor positive allosteric modulator") [neurosteroids](https://en.wikipedia.org/wiki/Neurosteroid "Neurosteroid") ([brexanolone](https://en.wikipedia.org/wiki/Allopregnanolone "Allopregnanolone"), [zuranolone](https://en.wikipedia.org/wiki/Zuranolone "Zuranolone")) [Hypericum perforatum (St. John's Wort)](https://en.wikipedia.org/wiki/Hypericum_perforatum "Hypericum perforatum") [Oxitriptan (5-HTP)](https://en.wikipedia.org/wiki/Oxitriptan "Oxitriptan") [Rubidium chloride (RbCl)](https://en.wikipedia.org/wiki/Rubidium_chloride "Rubidium chloride") [Tryptophan](https://en.wikipedia.org/wiki/Tryptophan "Tryptophan") \| \| \| \#[WHO-EM](https://en.wikipedia.org/wiki/WHO_Model_List_of_Essential_Medicines "WHO Model List of Essential Medicines") ‡[Withdrawn](https://en.wikipedia.org/wiki/List_of_withdrawn_drugs "List of withdrawn drugs") from market [Clinical trials](https://en.wikipedia.org/wiki/Clinical_trial "Clinical trial"): †[Phase III](https://en.wikipedia.org/wiki/Phases_of_clinical_research#Phase_III "Phases of clinical research") §Never to phase III \| \| \| [v](https://en.wikipedia.org/wiki/Template:Mood_stabilizers "Template:Mood stabilizers") [t](https://en.wikipedia.org/wiki/Template_talk:Mood_stabilizers "Template talk:Mood stabilizers") [e](https://en.wikipedia.org/wiki/Special:EditPage/Template:Mood_stabilizers "Special:EditPage/Template:Mood stabilizers")[Mood stabilizers](https://en.wikipedia.org/wiki/Mood_stabilizer "Mood stabilizer") \| \| \|---\|---\| \| [Anticonvulsants](https://en.wikipedia.org/wiki/Anticonvulsant "Anticonvulsant") \| [Carbamazepine](https://en.wikipedia.org/wiki/Carbamazepine "Carbamazepine") [Lamotrigine](https://en.wikipedia.org/wiki/Lamotrigine "Lamotrigine") [Oxcarbazepine](https://en.wikipedia.org/wiki/Oxcarbazepine "Oxcarbazepine") [Valproate](https://en.wikipedia.org/wiki/Valproate "Valproate") [Valnoctamide](https://en.wikipedia.org/wiki/Valnoctamide "Valnoctamide") [Valproate pivoxil](https://en.wikipedia.org/wiki/Valproate_pivoxil "Valproate pivoxil") [Valpromide](https://en.wikipedia.org/wiki/Valpromide "Valpromide") \| \| [Atypical antipsychotics](https://en.wikipedia.org/wiki/Atypical_antipsychotic "Atypical antipsychotic") \| [Aripiprazole](https://en.wikipedia.org/wiki/Aripiprazole "Aripiprazole") [Asenapine](https://en.wikipedia.org/wiki/Asenapine "Asenapine") [Cariprazine](https://en.wikipedia.org/wiki/Cariprazine "Cariprazine") [Clozapine](https://en.wikipedia.org/wiki/Clozapine "Clozapine") [Lurasidone](https://en.wikipedia.org/wiki/Lurasidone "Lurasidone") [Olanzapine](https://en.wikipedia.org/wiki/Olanzapine "Olanzapine") ([\+fluoxetine](https://en.wikipedia.org/wiki/Olanzapine/fluoxetine "Olanzapine/fluoxetine")) [Paliperidone](https://en.wikipedia.org/wiki/Paliperidone "Paliperidone") [Quetiapine](https://en.wikipedia.org/wiki/Quetiapine "Quetiapine") [Risperidone](https://en.wikipedia.org/wiki/Risperidone "Risperidone") [Ziprasidone](https://en.wikipedia.org/wiki/Ziprasidone "Ziprasidone") \| \| Others \| [Ketamine](https://en.wikipedia.org/wiki/Ketamine "Ketamine") [Lithium](https://en.wikipedia.org/wiki/Lithium_\(medication\) "Lithium (medication)") ([lithium acetate](https://en.wikipedia.org/wiki/Lithium_acetate "Lithium acetate"), [lithium carbonate](https://en.wikipedia.org/wiki/Lithium_carbonate "Lithium carbonate"), [lithium chloride](https://en.wikipedia.org/wiki/Lithium_chloride "Lithium chloride"), [lithium citrate](https://en.wikipedia.org/wiki/Lithium_citrate "Lithium citrate"), [lithium hydroxide](https://en.wikipedia.org/wiki/Lithium_hydroxide "Lithium hydroxide"), [lithium orotate](https://en.wikipedia.org/wiki/Lithium_orotate "Lithium orotate")) [Omega-3 fatty acids](https://en.wikipedia.org/wiki/Omega-3_fatty_acid "Omega-3 fatty acid") ([docosahexaenoic acid](https://en.wikipedia.org/wiki/Docosahexaenoic_acid "Docosahexaenoic acid"), [eicosapentaenoic acid](https://en.wikipedia.org/wiki/Eicosapentaenoic_acid "Eicosapentaenoic acid")) \| ![](https://en.wikipedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&usesul3=1) Retrieved from "<https://en.wikipedia.org/w/index.php?title=List_of_antidepressants&oldid=1289313995>" [Categories](https://en.wikipedia.org/wiki/Help:Category "Help:Category"): - [Antidepressants](https://en.wikipedia.org/wiki/Category:Antidepressants "Category:Antidepressants") - [Drug-related lists](https://en.wikipedia.org/wiki/Category:Drug-related_lists "Category:Drug-related lists") - [Mood stabilizers](https://en.wikipedia.org/wiki/Category:Mood_stabilizers "Category:Mood stabilizers") Hidden categories: - [Articles with short description](https://en.wikipedia.org/wiki/Category:Articles_with_short_description "Category:Articles with short description") - [Short description is different from Wikidata](https://en.wikipedia.org/wiki/Category:Short_description_is_different_from_Wikidata "Category:Short description is different from Wikidata") - This page was last edited on 7 May 2025, at 20:49 (UTC). - Text is available under the [Creative Commons Attribution-ShareAlike 4.0 License](https://en.wikipedia.org/wiki/Wikipedia:Text_of_the_Creative_Commons_Attribution-ShareAlike_4.0_International_License "Wikipedia:Text of the Creative Commons Attribution-ShareAlike 4.0 International License"); additional terms may apply. By using this site, you agree to the [Terms of Use](https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Terms_of_Use "foundation:Special:MyLanguage/Policy:Terms of Use") and [Privacy Policy](https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy "foundation:Special:MyLanguage/Policy:Privacy policy"). Wikipedia® is a registered trademark of the [Wikimedia Foundation, Inc.](https://wikimediafoundation.org/), a non-profit organization. - [Privacy policy](https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy) - [About Wikipedia](https://en.wikipedia.org/wiki/Wikipedia:About) - [Disclaimers](https://en.wikipedia.org/wiki/Wikipedia:General_disclaimer) - [Contact Wikipedia](https://en.wikipedia.org/wiki/Wikipedia:Contact_us) - [Code of Conduct](https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Universal_Code_of_Conduct) - [Developers](https://developer.wikimedia.org/) - [Statistics](https://stats.wikimedia.org/#/en.wikipedia.org) - [Cookie statement](https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Cookie_statement) - [Mobile view](https://en.m.wikipedia.org/w/index.php?title=List_of_antidepressants&mobileaction=toggle_view_mobile) - [![Wikimedia Foundation](https://en.wikipedia.org/static/images/footer/wikimedia.svg)](https://www.wikimedia.org/) - [![Powered by MediaWiki](https://en.wikipedia.org/w/resources/assets/mediawiki_compact.svg)](https://www.mediawiki.org/) Search Toggle the table of contents List of antidepressants 2 languages [Add topic](https://en.wikipedia.org/wiki/List_of_antidepressants)
Readable Markdown	null
Shard	152 (laksa)
Root Hash	17790707453426894952
Unparsed URL	org,wikipedia!en,/wiki/List_of_antidepressants s443